Cell type atlas - RPL35 - The Human Protein Atlas

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RPL35

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPL35
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein L35
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	593 NX
Lung	593 NX

Alveolar cells type 2	1127 NX
Lung	1127 NX

B-cells	4054 NX
Liver	4355 NX
Kidney	4206 NX
Colon	1232 NX

Basal glandular cells	3643 NX
Prostate	3643 NX

Basal keratinocytes	4892 NX
Skin	4892 NX

Bipolar cells	210 NX
Eye	210 NX

Cardiomyocytes	655 NX
Heart muscle	655 NX

Cholangiocytes	1603 NX
Liver	1603 NX

Ciliated cells	593 NX
Lung	593 NX

Club cells	1178 NX
Lung	1178 NX

Collecting duct cells	1077 NX
Kidney	1077 NX

Cone photoreceptor cells	81 NX
Eye	81 NX

Cytotrophoblasts	2511 NX
Placenta	2511 NX

Distal tubular cells	2290 NX
Kidney	2290 NX

Ductal cells	1953 NX
Pancreas	1953 NX

Early spermatids	1189 NX
Testis	1189 NX

Endothelial cells	2070 NX
Skin	3265 NX
Prostate	2654 NX
Liver	2396 NX
Testis	2168 NX
Placenta	2070 NX
Pancreas	1451 NX
Lung	843 NX
Eye	688 NX
Heart muscle	386 NX

Enterocytes	1495 NX
Small intestine	1767 NX
Colon	1440 NX
Rectum	879 NX

Erythroid cells	1448 NX
Liver	1448 NX

Exocrine glandular cells	5315 NX
Pancreas	5315 NX

Extravillous trophoblasts	3981 NX
Placenta	3981 NX

Fibroblasts	2376 NX
Skin	2506 NX
Placenta	2466 NX
Prostate	1410 NX
Lung	983 NX
Heart muscle	552 NX

Glandular cells	2324 NX
Prostate	2324 NX

Granulocytes	1249 NX
Lung	1672 NX
Colon	826 NX

Hepatocytes	2646 NX
Liver	2646 NX

Hofbauer cells	2485 NX
Placenta	2485 NX

Horizontal cells	103 NX
Eye	103 NX

Intestinal endocrine cells	1248 NX
Rectum	1627 NX
Colon	870 NX

Ito cells	1951 NX
Liver	1951 NX

Kupffer cells	2954 NX
Liver	2954 NX

Late spermatids	3494 NX
Testis	3494 NX

Leydig cells	2572 NX
Testis	2572 NX

Macrophages	3157 NX
Skin	4205 NX
Testis	3374 NX
Kidney	3289 NX
Prostate	3025 NX
Pancreas	1175 NX
Lung	1128 NX

Melanocytes	2676 NX
Skin	2676 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	2877 NX
Pancreas	2877 NX

Mucus-secreting cells	2738 NX
Rectum	3823 NX
Small intestine	2320 NX
Colon	2143 NX

Muller glia cells	358 NX
Eye	358 NX

Pancreatic endocrine cells	3375 NX
Pancreas	3375 NX

Paneth cells	1946 NX
Rectum	2892 NX
Small intestine	1946 NX
Colon	1540 NX

Peritubular cells	1208 NX
Testis	1208 NX

Proximal tubular cells	2551 NX
Kidney	2551 NX

Rod photoreceptor cells	285 NX
Eye	285 NX

Sertoli cells	977 NX
Testis	977 NX

Smooth muscle cells	2382 NX
Skin	3094 NX
Pancreas	2382 NX
Prostate	1889 NX
Heart muscle	632 NX

Spermatocytes	762 NX
Testis	762 NX

Spermatogonia	853 NX
Testis	853 NX

Suprabasal keratinocytes	6349 NX
Skin	6349 NX

Syncytiotrophoblasts	2061 NX
Placenta	2061 NX

T-cells	2554 NX
Skin	4691 NX
Kidney	3716 NX
Liver	2573 NX
Prostate	2554 NX
Lung	1472 NX
Colon	1047 NX

Undifferentiated cells	3546 NX
Small intestine	3749 NX
Rectum	3547 NX
Colon	1503 NX

Urothelial cells	3372 NX
Prostate	3372 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.