Cell type atlas - DPM2 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

DPM2

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	DPM2
Gene descriptionⁱ Full gene name according to HGNC.	Dolichyl-phosphate mannosyltransferase subunit 2, regulatory
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Erythroid cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Erythroid cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	27 NX
Lung	27 NX

Alveolar cells type 2	32 NX
Lung	32 NX

B-cells	25 NX
Liver	35 NX
Kidney	27 NX
Colon	24 NX

Basal glandular cells	31 NX
Prostate	31 NX

Basal keratinocytes	24 NX
Skin	24 NX

Bipolar cells	24 NX
Eye	24 NX

Cardiomyocytes	11 NX
Heart muscle	11 NX

Cholangiocytes	41 NX
Liver	41 NX

Ciliated cells	25 NX
Lung	25 NX

Club cells	31 NX
Lung	31 NX

Collecting duct cells	38 NX
Kidney	38 NX

Cone photoreceptor cells	16 NX
Eye	16 NX

Cytotrophoblasts	73 NX
Placenta	73 NX

Distal tubular cells	38 NX
Kidney	38 NX

Ductal cells	51 NX
Pancreas	51 NX

Early spermatids	6 NX
Testis	6 NX

Endothelial cells	29 NX
Placenta	63 NX
Pancreas	61 NX
Skin	38 NX
Prostate	36 NX
Testis	29 NX
Heart muscle	23 NX
Liver	22 NX
Lung	15 NX
Eye	14 NX

Enterocytes	36 NX
Colon	39 NX
Small intestine	35 NX
Rectum	29 NX

Erythroid cells	164 NX
Liver	164 NX

Exocrine glandular cells	51 NX
Pancreas	51 NX

Extravillous trophoblasts	89 NX
Placenta	89 NX

Fibroblasts	39 NX
Placenta	63 NX
Heart muscle	46 NX
Skin	30 NX
Prostate	29 NX
Lung	18 NX

Glandular cells	52 NX
Prostate	52 NX

Granulocytes	29 NX
Colon	37 NX
Lung	21 NX

Hepatocytes	27 NX
Liver	27 NX

Hofbauer cells	72 NX
Placenta	72 NX

Horizontal cells	37 NX
Eye	37 NX

Intestinal endocrine cells	31 NX
Rectum	35 NX
Colon	27 NX

Ito cells	35 NX
Liver	35 NX

Kupffer cells	23 NX
Liver	23 NX

Late spermatids	9 NX
Testis	9 NX

Leydig cells	25 NX
Testis	25 NX

Macrophages	26 NX
Pancreas	77 NX
Kidney	43 NX
Skin	28 NX
Testis	25 NX
Prostate	23 NX
Lung	19 NX

Melanocytes	30 NX
Skin	30 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	61 NX
Pancreas	61 NX

Mucus-secreting cells	42 NX
Colon	62 NX
Small intestine	47 NX
Rectum	35 NX

Muller glia cells	25 NX
Eye	25 NX

Pancreatic endocrine cells	50 NX
Pancreas	50 NX

Paneth cells	35 NX
Rectum	39 NX
Colon	35 NX
Small intestine	25 NX

Peritubular cells	19 NX
Testis	19 NX

Proximal tubular cells	39 NX
Kidney	39 NX

Rod photoreceptor cells	19 NX
Eye	19 NX

Sertoli cells	7 NX
Testis	7 NX

Smooth muscle cells	29 NX
Pancreas	92 NX
Prostate	32 NX
Heart muscle	29 NX
Skin	17 NX

Spermatocytes	15 NX
Testis	15 NX

Spermatogonia	21 NX
Testis	21 NX

Suprabasal keratinocytes	30 NX
Skin	30 NX

Syncytiotrophoblasts	54 NX
Placenta	54 NX

T-cells	31 NX
Kidney	45 NX
Liver	38 NX
Prostate	31 NX
Lung	29 NX
Colon	26 NX
Skin	25 NX

Undifferentiated cells	40 NX
Colon	54 NX
Small intestine	41 NX
Rectum	27 NX

Urothelial cells	33 NX
Prostate	33 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.