Cell type atlas - CHST12 - The Human Protein Atlas

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CHST12

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CHST12
Gene descriptionⁱ Full gene name according to HGNC.	Carbohydrate sulfotransferase 12
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Ito cells, T-cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (HMC-1, NB-4, U-266/70)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Ito cells, T-cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	15 NX
Lung	15 NX

Alveolar cells type 2	45 NX
Lung	44 NX

B-cells	41 NX
Liver	71 NX
Kidney	27 NX
Colon	15 NX

Basal glandular cells	35 NX
Prostate	35 NX

Basal keratinocytes	16 NX
Skin	16 NX

Bipolar cells	44 NX
Eye	44 NX

Cardiomyocytes	7 NX
Heart muscle	7 NX

Cholangiocytes	10 NX
Liver	10 NX

Ciliated cells	17 NX
Lung	17 NX

Club cells	31 NX
Lung	31 NX

Collecting duct cells	17 NX
Kidney	17 NX

Cone photoreceptor cells	63 NX
Eye	63 NX

Cytotrophoblasts	84 NX
Placenta	84 NX

Distal tubular cells	2 NX
Kidney	2 NX

Ductal cells	18 NX
Pancreas	18 NX

Early spermatids	4 NX
Testis	4 NX

Endothelial cells	45 NX
Placenta	81 NX
Testis	77 NX
Eye	65 NX
Liver	65 NX
Pancreas	61 NX
Skin	43 NX
Lung	35 NX
Prostate	34 NX
Heart muscle	18 NX

Enterocytes	7 NX
Small intestine	13 NX
Rectum	8 NX
Colon	2 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	14 NX
Pancreas	14 NX

Extravillous trophoblasts	9 NX
Placenta	9 NX

Fibroblasts	49 NX
Skin	51 NX
Placenta	50 NX
Prostate	32 NX
Lung	26 NX
Heart muscle	11 NX

Glandular cells	15 NX
Prostate	15 NX

Granulocytes	37 NX
Colon	37 NX
Lung	37 NX

Hepatocytes	6 NX
Liver	6 NX

Hofbauer cells	22 NX
Placenta	22 NX

Horizontal cells	45 NX
Eye	45 NX

Intestinal endocrine cells	12 NX
Rectum	21 NX
Colon	3 NX

Ito cells	159 NX
Liver	159 NX

Kupffer cells	22 NX
Liver	22 NX

Late spermatids	3 NX
Testis	3 NX

Leydig cells	89 NX
Testis	89 NX

Macrophages	20 NX
Lung	32 NX
Testis	22 NX
Pancreas	19 NX
Skin	17 NX
Prostate	13 NX
Kidney	12 NX

Melanocytes	20 NX
Skin	20 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	17 NX
Pancreas	17 NX

Mucus-secreting cells	9 NX
Small intestine	11 NX
Rectum	9 NX
Colon	4 NX

Muller glia cells	16 NX
Eye	16 NX

Pancreatic endocrine cells	13 NX
Pancreas	13 NX

Paneth cells	7 NX
Rectum	11 NX
Small intestine	7 NX
Colon	0 NX

Peritubular cells	64 NX
Testis	64 NX

Proximal tubular cells	10 NX
Kidney	10 NX

Rod photoreceptor cells	46 NX
Eye	46 NX

Sertoli cells	19 NX
Testis	19 NX

Smooth muscle cells	20 NX
Pancreas	31 NX
Prostate	22 NX
Skin	19 NX
Heart muscle	3 NX

Spermatocytes	28 NX
Testis	28 NX

Spermatogonia	19 NX
Testis	19 NX

Suprabasal keratinocytes	13 NX
Skin	13 NX

Syncytiotrophoblasts	112 NX
Placenta	112 NX

T-cells	129 NX
Liver	211 NX
Kidney	155 NX
Colon	129 NX
Skin	73 NX
Prostate	70 NX
Lung	48 NX

Undifferentiated cells	13 NX
Rectum	15 NX
Small intestine	12 NX
Colon	6 NX

Urothelial cells	9 NX
Prostate	9 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.