Cell type atlas - LMO7 - The Human Protein Atlas

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LMO7

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	LMO7
Gene descriptionⁱ Full gene name according to HGNC.	LIM domain 7
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	18

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Alveolar cells type 1, Club cells, Urothelial cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (naive CD4 T-cell)
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (BJ, fHDF/TERT166, LHCN-M2)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Alveolar cells type 1, Club cells, Urothelial cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	1563 NX
Lung	1563 NX

Alveolar cells type 2	242 NX
Lung	242 NX

B-cells	3 NX
Liver	8 NX
Colon	5 NX
Kidney	0 NX

Basal glandular cells	51 NX
Prostate	51 NX

Basal keratinocytes	21 NX
Skin	21 NX

Bipolar cells	5 NX
Eye	5 NX

Cardiomyocytes	309 NX
Heart muscle	309 NX

Cholangiocytes	48 NX
Liver	48 NX

Ciliated cells	234 NX
Lung	234 NX

Club cells	397 NX
Lung	397 NX

Collecting duct cells	59 NX
Kidney	59 NX

Cone photoreceptor cells	2 NX
Eye	2 NX

Cytotrophoblasts	39 NX
Placenta	39 NX

Distal tubular cells	13 NX
Kidney	13 NX

Ductal cells	57 NX
Pancreas	57 NX

Early spermatids	5 NX
Testis	5 NX

Endothelial cells	11 NX
Heart muscle	31 NX
Lung	20 NX
Prostate	14 NX
Testis	12 NX
Eye	11 NX
Placenta	4 NX
Skin	3 NX
Liver	0 NX
Pancreas	0 NX

Enterocytes	219 NX
Colon	450 NX
Rectum	196 NX
Small intestine	156 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	33 NX
Pancreas	33 NX

Extravillous trophoblasts	6 NX
Placenta	6 NX

Fibroblasts	67 NX
Lung	102 NX
Heart muscle	91 NX
Placenta	89 NX
Prostate	21 NX
Skin	9 NX

Glandular cells	251 NX
Prostate	251 NX

Granulocytes	20 NX
Lung	21 NX
Colon	18 NX

Hepatocytes	62 NX
Liver	62 NX

Hofbauer cells	5 NX
Placenta	5 NX

Horizontal cells	6 NX
Eye	6 NX

Intestinal endocrine cells	68 NX
Colon	78 NX
Rectum	59 NX

Ito cells	7 NX
Liver	7 NX

Kupffer cells	4 NX
Liver	4 NX

Late spermatids	6 NX
Testis	6 NX

Leydig cells	39 NX
Testis	39 NX

Macrophages	5 NX
Lung	27 NX
Prostate	12 NX
Testis	5 NX
Skin	2 NX
Kidney	1 NX
Pancreas	0 NX

Melanocytes	15 NX
Skin	15 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	2 NX
Pancreas	2 NX

Mucus-secreting cells	69 NX
Colon	145 NX
Small intestine	70 NX
Rectum	43 NX

Muller glia cells	2 NX
Eye	2 NX

Pancreatic endocrine cells	146 NX
Pancreas	146 NX

Paneth cells	65 NX
Colon	809 NX
Rectum	65 NX
Small intestine	53 NX

Peritubular cells	40 NX
Testis	40 NX

Proximal tubular cells	14 NX
Kidney	14 NX

Rod photoreceptor cells	11 NX
Eye	11 NX

Sertoli cells	13 NX
Testis	13 NX

Smooth muscle cells	19 NX
Pancreas	51 NX
Heart muscle	23 NX
Prostate	19 NX
Skin	5 NX

Spermatocytes	8 NX
Testis	8 NX

Spermatogonia	3 NX
Testis	3 NX

Suprabasal keratinocytes	40 NX
Skin	40 NX

Syncytiotrophoblasts	14 NX
Placenta	14 NX

T-cells	7 NX
Lung	39 NX
Prostate	9 NX
Colon	9 NX
Kidney	7 NX
Liver	6 NX
Skin	5 NX

Undifferentiated cells	44 NX
Colon	109 NX
Small intestine	53 NX
Rectum	37 NX

Urothelial cells	377 NX
Prostate	377 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.