Cell type atlas - TES - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

TES

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	TES
Gene descriptionⁱ Full gene name according to HGNC.	Testin LIM domain protein
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Early spermatids, Alveolar cells type 1)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (EFO-21, hTCEpi, SK-BR-3)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Early spermatids, Alveolar cells type 1)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	226 NX
Lung	226 NX

Alveolar cells type 2	36 NX
Lung	36 NX

B-cells	52 NX
Colon	64 NX
Liver	52 NX
Kidney	27 NX

Basal glandular cells	147 NX
Prostate	147 NX

Basal keratinocytes	178 NX
Skin	178 NX

Bipolar cells	2 NX
Eye	2 NX

Cardiomyocytes	15 NX
Heart muscle	15 NX

Cholangiocytes	38 NX
Liver	38 NX

Ciliated cells	84 NX
Lung	84 NX

Club cells	98 NX
Lung	98 NX

Collecting duct cells	35 NX
Kidney	35 NX

Cone photoreceptor cells	12 NX
Eye	12 NX

Cytotrophoblasts	17 NX
Placenta	17 NX

Distal tubular cells	18 NX
Kidney	18 NX

Ductal cells	105 NX
Pancreas	105 NX

Early spermatids	327 NX
Testis	327 NX

Endothelial cells	24 NX
Pancreas	61 NX
Skin	55 NX
Prostate	50 NX
Heart muscle	48 NX
Testis	24 NX
Eye	23 NX
Placenta	23 NX
Liver	22 NX
Lung	18 NX

Enterocytes	102 NX
Colon	172 NX
Rectum	82 NX
Small intestine	58 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	98 NX
Pancreas	98 NX

Extravillous trophoblasts	69 NX
Placenta	69 NX

Fibroblasts	27 NX
Heart muscle	31 NX
Lung	28 NX
Skin	27 NX
Placenta	23 NX
Prostate	12 NX

Glandular cells	83 NX
Prostate	83 NX

Granulocytes	17 NX
Lung	35 NX
Colon	0 NX

Hepatocytes	10 NX
Liver	10 NX

Hofbauer cells	15 NX
Placenta	15 NX

Horizontal cells	2 NX
Eye	2 NX

Intestinal endocrine cells	48 NX
Colon	78 NX
Rectum	19 NX

Ito cells	15 NX
Liver	15 NX

Kupffer cells	53 NX
Liver	53 NX

Late spermatids	82 NX
Testis	82 NX

Leydig cells	2 NX
Testis	2 NX

Macrophages	62 NX
Lung	79 NX
Prostate	74 NX
Skin	72 NX
Testis	64 NX
Kidney	60 NX
Pancreas	9 NX

Melanocytes	27 NX
Skin	27 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	36 NX
Pancreas	36 NX

Mucus-secreting cells	58 NX
Colon	155 NX
Small intestine	56 NX
Rectum	53 NX

Muller glia cells	23 NX
Eye	23 NX

Pancreatic endocrine cells	142 NX
Pancreas	142 NX

Paneth cells	59 NX
Colon	204 NX
Rectum	59 NX
Small intestine	35 NX

Peritubular cells	0 NX
Testis	0 NX

Proximal tubular cells	10 NX
Kidney	10 NX

Rod photoreceptor cells	13 NX
Eye	13 NX

Sertoli cells	7 NX
Testis	7 NX

Smooth muscle cells	21 NX
Heart muscle	32 NX
Pancreas	32 NX
Prostate	21 NX
Skin	13 NX

Spermatocytes	18 NX
Testis	18 NX

Spermatogonia	10 NX
Testis	10 NX

Suprabasal keratinocytes	107 NX
Skin	107 NX

Syncytiotrophoblasts	24 NX
Placenta	24 NX

T-cells	57 NX
Lung	129 NX
Prostate	118 NX
Liver	60 NX
Kidney	57 NX
Colon	46 NX
Skin	27 NX

Undifferentiated cells	44 NX
Colon	104 NX
Small intestine	46 NX
Rectum	43 NX

Urothelial cells	125 NX
Prostate	125 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.