Cell type atlas - GOLM1 - The Human Protein Atlas

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GOLM1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	GOLM1
Gene descriptionⁱ Full gene name according to HGNC.	Golgi membrane protein 1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Early spermatids, Paneth cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (U-266/70)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Early spermatids, Paneth cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	9 NX
Lung	9 NX

Alveolar cells type 2	12 NX
Lung	12 NX

B-cells	0 NX
Colon	7 NX
Kidney	0 NX
Liver	0 NX

Basal glandular cells	10 NX
Prostate	10 NX

Basal keratinocytes	2 NX
Skin	2 NX

Bipolar cells	17 NX
Eye	17 NX

Cardiomyocytes	4 NX
Heart muscle	4 NX

Cholangiocytes	71 NX
Liver	71 NX

Ciliated cells	70 NX
Lung	70 NX

Club cells	61 NX
Lung	61 NX

Collecting duct cells	33 NX
Kidney	33 NX

Cone photoreceptor cells	8 NX
Eye	8 NX

Cytotrophoblasts	5 NX
Placenta	5 NX

Distal tubular cells	22 NX
Kidney	22 NX

Ductal cells	148 NX
Pancreas	148 NX

Early spermatids	320 NX
Testis	320 NX

Endothelial cells	22 NX
Eye	37 NX
Prostate	31 NX
Liver	27 NX
Placenta	24 NX
Heart muscle	22 NX
Pancreas	22 NX
Lung	9 NX
Testis	7 NX
Skin	5 NX

Enterocytes	193 NX
Rectum	383 NX
Colon	280 NX
Small intestine	65 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	197 NX
Pancreas	197 NX

Extravillous trophoblasts	30 NX
Placenta	30 NX

Fibroblasts	21 NX
Placenta	42 NX
Lung	21 NX
Skin	17 NX
Prostate	17 NX
Heart muscle	7 NX

Glandular cells	131 NX
Prostate	131 NX

Granulocytes	1 NX
Lung	2 NX
Colon	0 NX

Hepatocytes	13 NX
Liver	13 NX

Hofbauer cells	10 NX
Placenta	10 NX

Horizontal cells	64 NX
Eye	64 NX

Intestinal endocrine cells	70 NX
Rectum	73 NX
Colon	68 NX

Ito cells	10 NX
Liver	10 NX

Kupffer cells	8 NX
Liver	8 NX

Late spermatids	197 NX
Testis	196 NX

Leydig cells	17 NX
Testis	17 NX

Macrophages	3 NX
Kidney	9 NX
Lung	8 NX
Prostate	4 NX
Pancreas	2 NX
Testis	2 NX
Skin	1 NX

Melanocytes	22 NX
Skin	22 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	1 NX
Pancreas	1 NX

Mucus-secreting cells	77 NX
Rectum	174 NX
Small intestine	58 NX
Colon	47 NX

Muller glia cells	16 NX
Eye	16 NX

Pancreatic endocrine cells	204 NX
Pancreas	204 NX

Paneth cells	285 NX
Rectum	310 NX
Colon	285 NX
Small intestine	119 NX

Peritubular cells	12 NX
Testis	12 NX

Proximal tubular cells	12 NX
Kidney	12 NX

Rod photoreceptor cells	6 NX
Eye	6 NX

Sertoli cells	0 NX
Testis	0 NX

Smooth muscle cells	10 NX
Pancreas	33 NX
Prostate	11 NX
Heart muscle	10 NX
Skin	6 NX

Spermatocytes	9 NX
Testis	9 NX

Spermatogonia	34 NX
Testis	34 NX

Suprabasal keratinocytes	1 NX
Skin	1 NX

Syncytiotrophoblasts	5 NX
Placenta	5 NX

T-cells	4 NX
Kidney	10 NX
Colon	7 NX
Lung	4 NX
Prostate	4 NX
Skin	3 NX
Liver	2 NX

Undifferentiated cells	129 NX
Colon	279 NX
Rectum	249 NX
Small intestine	104 NX

Urothelial cells	18 NX
Prostate	18 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.