Cell type atlas - SDF2 - The Human Protein Atlas

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SDF2

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	SDF2
Gene descriptionⁱ Full gene name according to HGNC.	Stromal cell derived factor 2
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	24 NX
Lung	24 NX

Alveolar cells type 2	20 NX
Lung	20 NX

B-cells	36 NX
Colon	61 NX
Kidney	31 NX
Liver	21 NX

Basal glandular cells	51 NX
Prostate	51 NX

Basal keratinocytes	30 NX
Skin	30 NX

Bipolar cells	25 NX
Eye	25 NX

Cardiomyocytes	10 NX
Heart muscle	10 NX

Cholangiocytes	28 NX
Liver	28 NX

Ciliated cells	20 NX
Lung	20 NX

Club cells	26 NX
Lung	26 NX

Collecting duct cells	40 NX
Kidney	40 NX

Cone photoreceptor cells	24 NX
Eye	24 NX

Cytotrophoblasts	110 NX
Placenta	110 NX

Distal tubular cells	25 NX
Kidney	25 NX

Ductal cells	68 NX
Pancreas	68 NX

Early spermatids	4 NX
Testis	4 NX

Endothelial cells	43 NX
Prostate	83 NX
Liver	74 NX
Placenta	72 NX
Testis	57 NX
Pancreas	43 NX
Skin	40 NX
Eye	38 NX
Heart muscle	26 NX
Lung	20 NX

Enterocytes	69 NX
Rectum	74 NX
Small intestine	69 NX
Colon	60 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	42 NX
Pancreas	42 NX

Extravillous trophoblasts	93 NX
Placenta	93 NX

Fibroblasts	54 NX
Placenta	78 NX
Prostate	61 NX
Skin	48 NX
Heart muscle	26 NX
Lung	20 NX

Glandular cells	50 NX
Prostate	50 NX

Granulocytes	21 NX
Colon	28 NX
Lung	14 NX

Hepatocytes	42 NX
Liver	42 NX

Hofbauer cells	50 NX
Placenta	50 NX

Horizontal cells	13 NX
Eye	13 NX

Intestinal endocrine cells	55 NX
Rectum	66 NX
Colon	44 NX

Ito cells	41 NX
Liver	41 NX

Kupffer cells	39 NX
Liver	39 NX

Late spermatids	2 NX
Testis	2 NX

Leydig cells	71 NX
Testis	71 NX

Macrophages	41 NX
Kidney	57 NX
Skin	46 NX
Testis	42 NX
Pancreas	40 NX
Prostate	36 NX
Lung	27 NX

Melanocytes	35 NX
Skin	35 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	47 NX
Pancreas	47 NX

Mucus-secreting cells	45 NX
Small intestine	71 NX
Colon	46 NX
Rectum	44 NX

Muller glia cells	48 NX
Eye	48 NX

Pancreatic endocrine cells	62 NX
Pancreas	62 NX

Paneth cells	84 NX
Colon	109 NX
Small intestine	84 NX
Rectum	50 NX

Peritubular cells	63 NX
Testis	63 NX

Proximal tubular cells	45 NX
Kidney	45 NX

Rod photoreceptor cells	26 NX
Eye	26 NX

Sertoli cells	71 NX
Testis	71 NX

Smooth muscle cells	33 NX
Pancreas	69 NX
Prostate	34 NX
Skin	30 NX
Heart muscle	22 NX

Spermatocytes	26 NX
Testis	26 NX

Spermatogonia	30 NX
Testis	30 NX

Suprabasal keratinocytes	33 NX
Skin	33 NX

Syncytiotrophoblasts	176 NX
Placenta	176 NX

T-cells	61 NX
Colon	74 NX
Liver	67 NX
Skin	60 NX
Kidney	55 NX
Prostate	31 NX
Lung	29 NX

Undifferentiated cells	41 NX
Small intestine	43 NX
Rectum	41 NX
Colon	37 NX

Urothelial cells	71 NX
Prostate	71 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.