Cell type atlas - UBE2G1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

UBE2G1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	UBE2G1
Gene descriptionⁱ Full gene name according to HGNC.	Ubiquitin conjugating enzyme E2 G1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Basal keratinocytes, Suprabasal keratinocytes)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Basal keratinocytes, Suprabasal keratinocytes)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	21 NX
Lung	21 NX

Alveolar cells type 2	12 NX
Lung	12 NX

B-cells	64 NX
Liver	108 NX
Kidney	71 NX
Colon	51 NX

Basal glandular cells	34 NX
Prostate	34 NX

Basal keratinocytes	254 NX
Skin	254 NX

Bipolar cells	17 NX
Eye	16 NX

Cardiomyocytes	63 NX
Heart muscle	63 NX

Cholangiocytes	31 NX
Liver	31 NX

Ciliated cells	13 NX
Lung	13 NX

Club cells	14 NX
Lung	14 NX

Collecting duct cells	24 NX
Kidney	24 NX

Cone photoreceptor cells	6 NX
Eye	6 NX

Cytotrophoblasts	37 NX
Placenta	37 NX

Distal tubular cells	70 NX
Kidney	70 NX

Ductal cells	28 NX
Pancreas	28 NX

Early spermatids	106 NX
Testis	106 NX

Endothelial cells	29 NX
Skin	75 NX
Prostate	43 NX
Placenta	34 NX
Testis	32 NX
Pancreas	29 NX
Liver	27 NX
Heart muscle	25 NX
Eye	16 NX
Lung	12 NX

Enterocytes	35 NX
Rectum	39 NX
Small intestine	36 NX
Colon	29 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	23 NX
Pancreas	23 NX

Extravillous trophoblasts	46 NX
Placenta	46 NX

Fibroblasts	34 NX
Skin	66 NX
Prostate	37 NX
Placenta	30 NX
Heart muscle	28 NX
Lung	18 NX

Glandular cells	47 NX
Prostate	47 NX

Granulocytes	21 NX
Colon	28 NX
Lung	14 NX

Hepatocytes	53 NX
Liver	53 NX

Hofbauer cells	41 NX
Placenta	41 NX

Horizontal cells	14 NX
Eye	14 NX

Intestinal endocrine cells	37 NX
Rectum	40 NX
Colon	34 NX

Ito cells	33 NX
Liver	33 NX

Kupffer cells	36 NX
Liver	36 NX

Late spermatids	173 NX
Testis	173 NX

Leydig cells	18 NX
Testis	18 NX

Macrophages	34 NX
Skin	62 NX
Testis	40 NX
Kidney	35 NX
Pancreas	33 NX
Prostate	31 NX
Lung	17 NX

Melanocytes	64 NX
Skin	64 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	33 NX
Pancreas	33 NX

Mucus-secreting cells	33 NX
Rectum	39 NX
Colon	35 NX
Small intestine	28 NX

Muller glia cells	23 NX
Eye	23 NX

Pancreatic endocrine cells	33 NX
Pancreas	33 NX

Paneth cells	28 NX
Small intestine	35 NX
Rectum	28 NX
Colon	20 NX

Peritubular cells	20 NX
Testis	20 NX

Proximal tubular cells	61 NX
Kidney	61 NX

Rod photoreceptor cells	14 NX
Eye	14 NX

Sertoli cells	7 NX
Testis	7 NX

Smooth muscle cells	48 NX
Skin	78 NX
Prostate	48 NX
Pancreas	35 NX
Heart muscle	27 NX

Spermatocytes	64 NX
Testis	64 NX

Spermatogonia	48 NX
Testis	48 NX

Suprabasal keratinocytes	210 NX
Skin	210 NX

Syncytiotrophoblasts	56 NX
Placenta	56 NX

T-cells	43 NX
Skin	123 NX
Prostate	61 NX
Colon	53 NX
Kidney	43 NX
Liver	36 NX
Lung	25 NX

Undifferentiated cells	27 NX
Small intestine	28 NX
Rectum	27 NX
Colon	26 NX

Urothelial cells	53 NX
Prostate	53 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.