Cell type atlas - NINJ1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

NINJ1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	NINJ1
Gene descriptionⁱ Full gene name according to HGNC.	Ninjurin 1
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Hofbauer cells, monocytes)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (neutrophil)
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (Hep G2, HHSteC, MCF7)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Hofbauer cells, monocytes)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	27 NX
Lung	27 NX

Alveolar cells type 2	38 NX
Lung	38 NX

B-cells	14 NX
Colon	100 NX
Kidney	18 NX
Liver	5 NX

Basal glandular cells	84 NX
Prostate	84 NX

Basal keratinocytes	102 NX
Skin	102 NX

Bipolar cells	2 NX
Eye	2 NX

Cardiomyocytes	27 NX
Heart muscle	27 NX

Cholangiocytes	59 NX
Liver	59 NX

Ciliated cells	3 NX
Lung	3 NX

Club cells	32 NX
Lung	32 NX

Collecting duct cells	38 NX
Kidney	38 NX

Cone photoreceptor cells	0 NX
Eye	0 NX

Cytotrophoblasts	110 NX
Placenta	110 NX

Distal tubular cells	110 NX
Kidney	110 NX

Ductal cells	87 NX
Pancreas	87 NX

Early spermatids	2 NX
Testis	2 NX

Endothelial cells	47 NX
Skin	151 NX
Prostate	74 NX
Placenta	67 NX
Eye	61 NX
Lung	47 NX
Testis	19 NX
Pancreas	18 NX
Heart muscle	17 NX
Liver	5 NX

Enterocytes	23 NX
Small intestine	65 NX
Rectum	17 NX
Colon	13 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	90 NX
Pancreas	90 NX

Extravillous trophoblasts	67 NX
Placenta	67 NX

Fibroblasts	79 NX
Prostate	250 NX
Skin	118 NX
Lung	49 NX
Placenta	43 NX
Heart muscle	19 NX

Glandular cells	64 NX
Prostate	64 NX

Granulocytes	47 NX
Colon	74 NX
Lung	21 NX

Hepatocytes	36 NX
Liver	36 NX

Hofbauer cells	430 NX
Placenta	430 NX

Horizontal cells	2 NX
Eye	2 NX

Intestinal endocrine cells	17 NX
Rectum	21 NX
Colon	14 NX

Ito cells	23 NX
Liver	23 NX

Kupffer cells	132 NX
Liver	132 NX

Late spermatids	11 NX
Testis	11 NX

Leydig cells	39 NX
Testis	39 NX

Macrophages	172 NX
Prostate	837 NX
Pancreas	473 NX
Skin	432 NX
Kidney	213 NX
Testis	70 NX
Lung	51 NX

Melanocytes	140 NX
Skin	140 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	299 NX
Pancreas	299 NX

Mucus-secreting cells	19 NX
Small intestine	24 NX
Colon	21 NX
Rectum	14 NX

Muller glia cells	49 NX
Eye	49 NX

Pancreatic endocrine cells	57 NX
Pancreas	57 NX

Paneth cells	25 NX
Colon	26 NX
Small intestine	25 NX
Rectum	14 NX

Peritubular cells	68 NX
Testis	68 NX

Proximal tubular cells	195 NX
Kidney	195 NX

Rod photoreceptor cells	3 NX
Eye	3 NX

Sertoli cells	13 NX
Testis	13 NX

Smooth muscle cells	89 NX
Skin	140 NX
Prostate	97 NX
Pancreas	55 NX
Heart muscle	48 NX

Spermatocytes	1 NX
Testis	1 NX

Spermatogonia	7 NX
Testis	7 NX

Suprabasal keratinocytes	119 NX
Skin	119 NX

Syncytiotrophoblasts	61 NX
Placenta	61 NX

T-cells	42 NX
Prostate	109 NX
Colon	107 NX
Skin	103 NX
Kidney	50 NX
Lung	35 NX
Liver	27 NX

Undifferentiated cells	18 NX
Small intestine	22 NX
Rectum	18 NX
Colon	14 NX

Urothelial cells	50 NX
Prostate	50 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.