Cell type atlas - RPL27 - The Human Protein Atlas

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RPL27

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPL27
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein L27
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Cancer-related genes Disease related genes Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	682 NX
Lung	682 NX

Alveolar cells type 2	960 NX
Lung	960 NX

B-cells	2745 NX
Liver	3056 NX
Kidney	2580 NX
Colon	1181 NX

Basal glandular cells	1731 NX
Prostate	1731 NX

Basal keratinocytes	2248 NX
Skin	2248 NX

Bipolar cells	124 NX
Eye	124 NX

Cardiomyocytes	671 NX
Heart muscle	671 NX

Cholangiocytes	1246 NX
Liver	1246 NX

Ciliated cells	628 NX
Lung	628 NX

Club cells	1104 NX
Lung	1104 NX

Collecting duct cells	492 NX
Kidney	492 NX

Cone photoreceptor cells	84 NX
Eye	84 NX

Cytotrophoblasts	1812 NX
Placenta	1812 NX

Distal tubular cells	1268 NX
Kidney	1268 NX

Ductal cells	1382 NX
Pancreas	1382 NX

Early spermatids	340 NX
Testis	340 NX

Endothelial cells	1526 NX
Testis	1997 NX
Prostate	1888 NX
Skin	1820 NX
Placenta	1591 NX
Liver	1526 NX
Pancreas	1067 NX
Lung	750 NX
Eye	499 NX
Heart muscle	410 NX

Enterocytes	906 NX
Small intestine	1027 NX
Colon	898 NX
Rectum	748 NX

Erythroid cells	701 NX
Liver	701 NX

Exocrine glandular cells	2627 NX
Pancreas	2627 NX

Extravillous trophoblasts	2978 NX
Placenta	2978 NX

Fibroblasts	1477 NX
Placenta	1599 NX
Lung	1513 NX
Skin	1428 NX
Prostate	1070 NX
Heart muscle	431 NX

Glandular cells	1639 NX
Prostate	1639 NX

Granulocytes	948 NX
Lung	1244 NX
Colon	652 NX

Hepatocytes	1517 NX
Liver	1517 NX

Hofbauer cells	1848 NX
Placenta	1848 NX

Horizontal cells	62 NX
Eye	62 NX

Intestinal endocrine cells	877 NX
Rectum	1053 NX
Colon	700 NX

Ito cells	1299 NX
Liver	1299 NX

Kupffer cells	2145 NX
Liver	2145 NX

Late spermatids	659 NX
Testis	659 NX

Leydig cells	2254 NX
Testis	2254 NX

Macrophages	2398 NX
Testis	3752 NX
Prostate	2656 NX
Skin	2610 NX
Kidney	2271 NX
Lung	1439 NX
Pancreas	882 NX

Melanocytes	1353 NX
Skin	1353 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	2461 NX
Pancreas	2461 NX

Mucus-secreting cells	1687 NX
Rectum	2746 NX
Colon	1623 NX
Small intestine	1185 NX

Muller glia cells	281 NX
Eye	281 NX

Pancreatic endocrine cells	2398 NX
Pancreas	2398 NX

Paneth cells	1157 NX
Rectum	2048 NX
Small intestine	1157 NX
Colon	1097 NX

Peritubular cells	1203 NX
Testis	1203 NX

Proximal tubular cells	1661 NX
Kidney	1661 NX

Rod photoreceptor cells	157 NX
Eye	157 NX

Sertoli cells	854 NX
Testis	854 NX

Smooth muscle cells	1593 NX
Pancreas	1936 NX
Skin	1850 NX
Prostate	1370 NX
Heart muscle	573 NX

Spermatocytes	458 NX
Testis	458 NX

Spermatogonia	394 NX
Testis	394 NX

Suprabasal keratinocytes	2947 NX
Skin	2947 NX

Syncytiotrophoblasts	1827 NX
Placenta	1827 NX

T-cells	1797 NX
Skin	2765 NX
Kidney	2400 NX
Liver	2008 NX
Prostate	1743 NX
Lung	1317 NX
Colon	1011 NX

Undifferentiated cells	2038 NX
Rectum	2379 NX
Small intestine	2038 NX
Colon	1236 NX

Urothelial cells	2133 NX
Prostate	2133 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.