Cell type atlas - NDUFA10 - The Human Protein Atlas

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NDUFA10

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	NDUFA10
Gene descriptionⁱ Full gene name according to HGNC.	NADH:ubiquinone oxidoreductase subunit A10
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	9

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	72 NX
Lung	72 NX

Alveolar cells type 2	72 NX
Lung	72 NX

B-cells	71 NX
Kidney	80 NX
Colon	69 NX
Liver	37 NX

Basal glandular cells	82 NX
Prostate	82 NX

Basal keratinocytes	93 NX
Skin	93 NX

Bipolar cells	72 NX
Eye	72 NX

Cardiomyocytes	305 NX
Heart muscle	305 NX

Cholangiocytes	79 NX
Liver	79 NX

Ciliated cells	78 NX
Lung	78 NX

Club cells	81 NX
Lung	81 NX

Collecting duct cells	73 NX
Kidney	73 NX

Cone photoreceptor cells	59 NX
Eye	59 NX

Cytotrophoblasts	176 NX
Placenta	176 NX

Distal tubular cells	264 NX
Kidney	264 NX

Ductal cells	96 NX
Pancreas	96 NX

Early spermatids	40 NX
Testis	40 NX

Endothelial cells	66 NX
Placenta	86 NX
Skin	81 NX
Heart muscle	75 NX
Eye	66 NX
Pancreas	57 NX
Testis	56 NX
Lung	55 NX
Prostate	51 NX
Liver	38 NX

Enterocytes	150 NX
Colon	156 NX
Small intestine	150 NX
Rectum	115 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	68 NX
Pancreas	68 NX

Extravillous trophoblasts	98 NX
Placenta	98 NX

Fibroblasts	68 NX
Heart muscle	131 NX
Placenta	85 NX
Skin	66 NX
Lung	44 NX
Prostate	37 NX

Glandular cells	54 NX
Prostate	54 NX

Granulocytes	65 NX
Colon	74 NX
Lung	56 NX

Hepatocytes	119 NX
Liver	119 NX

Hofbauer cells	111 NX
Placenta	111 NX

Horizontal cells	48 NX
Eye	48 NX

Intestinal endocrine cells	89 NX
Rectum	94 NX
Colon	85 NX

Ito cells	63 NX
Liver	63 NX

Kupffer cells	84 NX
Liver	84 NX

Late spermatids	49 NX
Testis	49 NX

Leydig cells	46 NX
Testis	46 NX

Macrophages	74 NX
Lung	85 NX
Kidney	82 NX
Skin	79 NX
Prostate	72 NX
Testis	69 NX
Pancreas	68 NX

Melanocytes	106 NX
Skin	106 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	115 NX
Pancreas	115 NX

Mucus-secreting cells	135 NX
Colon	159 NX
Rectum	145 NX
Small intestine	89 NX

Muller glia cells	70 NX
Eye	70 NX

Pancreatic endocrine cells	75 NX
Pancreas	75 NX

Paneth cells	107 NX
Rectum	142 NX
Colon	107 NX
Small intestine	91 NX

Peritubular cells	46 NX
Testis	46 NX

Proximal tubular cells	181 NX
Kidney	181 NX

Rod photoreceptor cells	103 NX
Eye	103 NX

Sertoli cells	65 NX
Testis	65 NX

Smooth muscle cells	75 NX
Pancreas	101 NX
Skin	81 NX
Prostate	75 NX
Heart muscle	73 NX

Spermatocytes	53 NX
Testis	53 NX

Spermatogonia	69 NX
Testis	69 NX

Suprabasal keratinocytes	104 NX
Skin	104 NX

Syncytiotrophoblasts	182 NX
Placenta	182 NX

T-cells	62 NX
Kidney	80 NX
Skin	68 NX
Lung	68 NX
Prostate	61 NX
Colon	59 NX
Liver	57 NX

Undifferentiated cells	201 NX
Colon	226 NX
Rectum	201 NX
Small intestine	167 NX

Urothelial cells	84 NX
Prostate	84 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.