Cell type atlas - MRPS12 - The Human Protein Atlas

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MRPS12

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MRPS12
Gene descriptionⁱ Full gene name according to HGNC.	Mitochondrial ribosomal protein S12
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (A549)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	21 NX
Lung	21 NX

Alveolar cells type 2	22 NX
Lung	22 NX

B-cells	72 NX
Liver	84 NX
Kidney	76 NX
Colon	67 NX

Basal glandular cells	48 NX
Prostate	48 NX

Basal keratinocytes	82 NX
Skin	82 NX

Bipolar cells	18 NX
Eye	18 NX

Cardiomyocytes	52 NX
Heart muscle	52 NX

Cholangiocytes	82 NX
Liver	82 NX

Ciliated cells	24 NX
Lung	24 NX

Club cells	25 NX
Lung	25 NX

Collecting duct cells	63 NX
Kidney	63 NX

Cone photoreceptor cells	22 NX
Eye	22 NX

Cytotrophoblasts	107 NX
Placenta	107 NX

Distal tubular cells	244 NX
Kidney	244 NX

Ductal cells	108 NX
Pancreas	108 NX

Early spermatids	27 NX
Testis	27 NX

Endothelial cells	42 NX
Placenta	62 NX
Skin	60 NX
Prostate	57 NX
Pancreas	57 NX
Testis	42 NX
Liver	27 NX
Heart muscle	25 NX
Eye	24 NX
Lung	15 NX

Enterocytes	115 NX
Small intestine	118 NX
Colon	106 NX
Rectum	50 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	99 NX
Pancreas	99 NX

Extravillous trophoblasts	127 NX
Placenta	127 NX

Fibroblasts	50 NX
Placenta	57 NX
Heart muscle	56 NX
Skin	46 NX
Prostate	41 NX
Lung	28 NX

Glandular cells	59 NX
Prostate	59 NX

Granulocytes	27 NX
Lung	35 NX
Colon	18 NX

Hepatocytes	137 NX
Liver	137 NX

Hofbauer cells	92 NX
Placenta	92 NX

Horizontal cells	22 NX
Eye	22 NX

Intestinal endocrine cells	50 NX
Rectum	73 NX
Colon	27 NX

Ito cells	27 NX
Liver	27 NX

Kupffer cells	53 NX
Liver	53 NX

Late spermatids	54 NX
Testis	54 NX

Leydig cells	35 NX
Testis	35 NX

Macrophages	45 NX
Pancreas	117 NX
Kidney	97 NX
Prostate	45 NX
Testis	44 NX
Skin	44 NX
Lung	28 NX

Melanocytes	51 NX
Skin	51 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	123 NX
Pancreas	123 NX

Mucus-secreting cells	92 NX
Colon	149 NX
Rectum	89 NX
Small intestine	69 NX

Muller glia cells	17 NX
Eye	17 NX

Pancreatic endocrine cells	104 NX
Pancreas	104 NX

Paneth cells	56 NX
Rectum	91 NX
Small intestine	56 NX
Colon	14 NX

Peritubular cells	31 NX
Testis	31 NX

Proximal tubular cells	164 NX
Kidney	164 NX

Rod photoreceptor cells	20 NX
Eye	20 NX

Sertoli cells	32 NX
Testis	32 NX

Smooth muscle cells	39 NX
Pancreas	140 NX
Prostate	39 NX
Skin	37 NX
Heart muscle	32 NX

Spermatocytes	19 NX
Testis	19 NX

Spermatogonia	31 NX
Testis	31 NX

Suprabasal keratinocytes	94 NX
Skin	94 NX

Syncytiotrophoblasts	86 NX
Placenta	86 NX

T-cells	58 NX
Kidney	81 NX
Liver	63 NX
Colon	60 NX
Skin	57 NX
Lung	32 NX
Prostate	0 NX

Undifferentiated cells	125 NX
Colon	169 NX
Rectum	122 NX
Small intestine	119 NX

Urothelial cells	80 NX
Prostate	80 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.