Cell type atlas - UQCR11 - The Human Protein Atlas

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UQCR11

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	UQCR11
Gene descriptionⁱ Full gene name according to HGNC.	Ubiquinol-cytochrome c reductase, complex III subunit XI
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	250 NX
Lung	250 NX

Alveolar cells type 2	365 NX
Lung	365 NX

B-cells	312 NX
Liver	438 NX
Kidney	401 NX
Colon	0 NX

Basal glandular cells	148 NX
Prostate	148 NX

Basal keratinocytes	0 NX
Skin	0 NX

Bipolar cells	117 NX
Eye	117 NX

Cardiomyocytes	1546 NX
Heart muscle	1546 NX

Cholangiocytes	581 NX
Liver	581 NX

Ciliated cells	491 NX
Lung	491 NX

Club cells	294 NX
Lung	294 NX

Collecting duct cells	602 NX
Kidney	602 NX

Cone photoreceptor cells	37 NX
Eye	37 NX

Cytotrophoblasts	422 NX
Placenta	422 NX

Distal tubular cells	1519 NX
Kidney	1519 NX

Ductal cells	594 NX
Pancreas	594 NX

Early spermatids	134 NX
Testis	134 NX

Endothelial cells	281 NX
Placenta	467 NX
Liver	409 NX
Pancreas	362 NX
Heart muscle	321 NX
Lung	306 NX
Testis	264 NX
Eye	201 NX
Prostate	148 NX
Skin	0 NX

Enterocytes	1268 NX
Small intestine	1692 NX
Rectum	1569 NX
Colon	0 NX

Erythroid cells	350 NX
Liver	350 NX

Exocrine glandular cells	708 NX
Pancreas	708 NX

Extravillous trophoblasts	511 NX
Placenta	511 NX

Fibroblasts	325 NX
Heart muscle	609 NX
Placenta	382 NX
Lung	328 NX
Prostate	102 NX
Skin	0 NX

Glandular cells	312 NX
Prostate	312 NX

Granulocytes	184 NX
Lung	367 NX
Colon	0 NX

Hepatocytes	1781 NX
Liver	1781 NX

Hofbauer cells	835 NX
Placenta	835 NX

Horizontal cells	84 NX
Eye	84 NX

Intestinal endocrine cells	437 NX
Rectum	873 NX
Colon	0 NX

Ito cells	444 NX
Liver	444 NX

Kupffer cells	741 NX
Liver	741 NX

Late spermatids	307 NX
Testis	307 NX

Leydig cells	234 NX
Testis	234 NX

Macrophages	457 NX
Pancreas	891 NX
Kidney	849 NX
Lung	544 NX
Testis	383 NX
Prostate	209 NX
Skin	0 NX

Melanocytes	0 NX
Skin	0 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	926 NX
Pancreas	926 NX

Mucus-secreting cells	941 NX
Rectum	1040 NX
Small intestine	874 NX
Colon	0 NX

Muller glia cells	194 NX
Eye	194 NX

Pancreatic endocrine cells	713 NX
Pancreas	713 NX

Paneth cells	958 NX
Small intestine	1049 NX
Rectum	958 NX
Colon	0 NX

Peritubular cells	244 NX
Testis	244 NX

Proximal tubular cells	854 NX
Kidney	854 NX

Rod photoreceptor cells	119 NX
Eye	119 NX

Sertoli cells	220 NX
Testis	220 NX

Smooth muscle cells	180 NX
Pancreas	569 NX
Heart muscle	513 NX
Prostate	180 NX
Skin	0 NX

Spermatocytes	157 NX
Testis	157 NX

Spermatogonia	128 NX
Testis	128 NX

Suprabasal keratinocytes	0 NX
Skin	0 NX

Syncytiotrophoblasts	429 NX
Placenta	429 NX

T-cells	332 NX
Kidney	504 NX
Lung	417 NX
Liver	339 NX
Prostate	140 NX
Colon	0 NX
Skin	0 NX

Undifferentiated cells	797 NX
Rectum	1210 NX
Small intestine	797 NX
Colon	0 NX

Urothelial cells	248 NX
Prostate	248 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.