Cell type atlas - PRMT1 - The Human Protein Atlas

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PRMT1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	PRMT1
Gene descriptionⁱ Full gene name according to HGNC.	Protein arginine methyltransferase 1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	11

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	3 NX
Lung	3 NX

Alveolar cells type 2	16 NX
Lung	16 NX

B-cells	80 NX
Liver	126 NX
Kidney	85 NX
Colon	76 NX

Basal glandular cells	188 NX
Prostate	188 NX

Basal keratinocytes	184 NX
Skin	184 NX

Bipolar cells	239 NX
Eye	239 NX

Cardiomyocytes	13 NX
Heart muscle	13 NX

Cholangiocytes	28 NX
Liver	28 NX

Ciliated cells	1 NX
Lung	1 NX

Club cells	8 NX
Lung	8 NX

Collecting duct cells	42 NX
Kidney	42 NX

Cone photoreceptor cells	100 NX
Eye	100 NX

Cytotrophoblasts	171 NX
Placenta	171 NX

Distal tubular cells	108 NX
Kidney	108 NX

Ductal cells	159 NX
Pancreas	159 NX

Early spermatids	4 NX
Testis	3 NX

Endothelial cells	104 NX
Testis	359 NX
Placenta	216 NX
Pancreas	215 NX
Prostate	176 NX
Skin	158 NX
Eye	104 NX
Liver	54 NX
Heart muscle	8 NX
Lung	6 NX

Enterocytes	28 NX
Colon	28 NX
Small intestine	27 NX
Rectum	23 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	117 NX
Pancreas	117 NX

Extravillous trophoblasts	137 NX
Placenta	137 NX

Fibroblasts	110 NX
Prostate	193 NX
Placenta	144 NX
Skin	86 NX
Heart muscle	12 NX
Lung	6 NX

Glandular cells	82 NX
Prostate	82 NX

Granulocytes	55 NX
Colon	92 NX
Lung	19 NX

Hepatocytes	18 NX
Liver	18 NX

Hofbauer cells	92 NX
Placenta	92 NX

Horizontal cells	122 NX
Eye	122 NX

Intestinal endocrine cells	111 NX
Colon	146 NX
Rectum	75 NX

Ito cells	96 NX
Liver	96 NX

Kupffer cells	31 NX
Liver	31 NX

Late spermatids	13 NX
Testis	13 NX

Leydig cells	96 NX
Testis	96 NX

Macrophages	66 NX
Skin	111 NX
Pancreas	94 NX
Prostate	68 NX
Testis	64 NX
Kidney	57 NX
Lung	7 NX

Melanocytes	106 NX
Skin	106 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	237 NX
Pancreas	237 NX

Mucus-secreting cells	62 NX
Colon	96 NX
Rectum	62 NX
Small intestine	39 NX

Muller glia cells	106 NX
Eye	106 NX

Pancreatic endocrine cells	105 NX
Pancreas	105 NX

Paneth cells	52 NX
Small intestine	53 NX
Rectum	52 NX
Colon	20 NX

Peritubular cells	84 NX
Testis	84 NX

Proximal tubular cells	64 NX
Kidney	64 NX

Rod photoreceptor cells	131 NX
Eye	131 NX

Sertoli cells	91 NX
Testis	91 NX

Smooth muscle cells	133 NX
Pancreas	214 NX
Skin	135 NX
Prostate	117 NX
Heart muscle	9 NX

Spermatocytes	70 NX
Testis	70 NX

Spermatogonia	132 NX
Testis	132 NX

Suprabasal keratinocytes	139 NX
Skin	139 NX

Syncytiotrophoblasts	197 NX
Placenta	197 NX

T-cells	52 NX
Skin	113 NX
Kidney	112 NX
Prostate	70 NX
Colon	70 NX
Liver	46 NX
Lung	13 NX

Undifferentiated cells	84 NX
Colon	140 NX
Small intestine	86 NX
Rectum	80 NX

Urothelial cells	157 NX
Prostate	157 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.