Cell type atlas - USP9X - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

USP9X

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	USP9X
Gene descriptionⁱ Full gene name according to HGNC.	Ubiquitin specific peptidase 9, X-linked
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes Enzymes Potential drug targets
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	39 NX
Lung	39 NX

Alveolar cells type 2	32 NX
Lung	32 NX

B-cells	24 NX
Colon	36 NX
Liver	22 NX
Kidney	18 NX

Basal glandular cells	27 NX
Prostate	27 NX

Basal keratinocytes	43 NX
Skin	43 NX

Bipolar cells	35 NX
Eye	35 NX

Cardiomyocytes	74 NX
Heart muscle	74 NX

Cholangiocytes	43 NX
Liver	43 NX

Ciliated cells	31 NX
Lung	31 NX

Club cells	36 NX
Lung	36 NX

Collecting duct cells	26 NX
Kidney	26 NX

Cone photoreceptor cells	35 NX
Eye	35 NX

Cytotrophoblasts	31 NX
Placenta	31 NX

Distal tubular cells	7 NX
Kidney	7 NX

Ductal cells	27 NX
Pancreas	27 NX

Early spermatids	13 NX
Testis	13 NX

Endothelial cells	40 NX
Heart muscle	59 NX
Eye	41 NX
Skin	41 NX
Liver	41 NX
Testis	40 NX
Prostate	39 NX
Lung	35 NX
Placenta	24 NX
Pancreas	22 NX

Enterocytes	39 NX
Rectum	70 NX
Small intestine	42 NX
Colon	29 NX

Erythroid cells	70 NX
Liver	70 NX

Exocrine glandular cells	23 NX
Pancreas	23 NX

Extravillous trophoblasts	22 NX
Placenta	22 NX

Fibroblasts	35 NX
Heart muscle	67 NX
Lung	41 NX
Skin	37 NX
Placenta	30 NX
Prostate	28 NX

Glandular cells	30 NX
Prostate	30 NX

Granulocytes	24 NX
Lung	40 NX
Colon	9 NX

Hepatocytes	56 NX
Liver	56 NX

Hofbauer cells	29 NX
Placenta	29 NX

Horizontal cells	35 NX
Eye	35 NX

Intestinal endocrine cells	26 NX
Colon	31 NX
Rectum	21 NX

Ito cells	53 NX
Liver	53 NX

Kupffer cells	43 NX
Liver	43 NX

Late spermatids	13 NX
Testis	13 NX

Leydig cells	31 NX
Testis	31 NX

Macrophages	38 NX
Prostate	53 NX
Testis	49 NX
Skin	39 NX
Lung	37 NX
Kidney	21 NX
Pancreas	9 NX

Melanocytes	32 NX
Skin	32 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	33 NX
Pancreas	33 NX

Mucus-secreting cells	43 NX
Small intestine	56 NX
Rectum	44 NX
Colon	12 NX

Muller glia cells	32 NX
Eye	32 NX

Pancreatic endocrine cells	27 NX
Pancreas	27 NX

Paneth cells	36 NX
Small intestine	39 NX
Rectum	36 NX
Colon	35 NX

Peritubular cells	46 NX
Testis	46 NX

Proximal tubular cells	20 NX
Kidney	20 NX

Rod photoreceptor cells	29 NX
Eye	29 NX

Sertoli cells	32 NX
Testis	32 NX

Smooth muscle cells	40 NX
Heart muscle	62 NX
Skin	40 NX
Prostate	36 NX
Pancreas	31 NX

Spermatocytes	31 NX
Testis	31 NX

Spermatogonia	69 NX
Testis	69 NX

Suprabasal keratinocytes	48 NX
Skin	48 NX

Syncytiotrophoblasts	39 NX
Placenta	39 NX

T-cells	26 NX
Colon	35 NX
Skin	30 NX
Prostate	26 NX
Lung	26 NX
Liver	25 NX
Kidney	16 NX

Undifferentiated cells	37 NX
Rectum	40 NX
Small intestine	38 NX
Colon	22 NX

Urothelial cells	34 NX
Prostate	34 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.