Cell type atlas - ATG101 - The Human Protein Atlas

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ATG101

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	ATG101
Gene descriptionⁱ Full gene name according to HGNC.	Autophagy related 101
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Transporters
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enriched (plasmacytoid DC)
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	18 NX
Lung	18 NX

Alveolar cells type 2	22 NX
Lung	22 NX

B-cells	44 NX
Colon	57 NX
Liver	44 NX
Kidney	36 NX

Basal glandular cells	90 NX
Prostate	90 NX

Basal keratinocytes	0 NX
Skin	0 NX

Bipolar cells	15 NX
Eye	15 NX

Cardiomyocytes	3 NX
Heart muscle	3 NX

Cholangiocytes	41 NX
Liver	41 NX

Ciliated cells	17 NX
Lung	17 NX

Club cells	18 NX
Lung	18 NX

Collecting duct cells	28 NX
Kidney	28 NX

Cone photoreceptor cells	12 NX
Eye	12 NX

Cytotrophoblasts	45 NX
Placenta	45 NX

Distal tubular cells	60 NX
Kidney	60 NX

Ductal cells	57 NX
Pancreas	57 NX

Early spermatids	11 NX
Testis	10 NX

Endothelial cells	24 NX
Prostate	84 NX
Pancreas	39 NX
Eye	38 NX
Placenta	37 NX
Liver	25 NX
Testis	24 NX
Lung	9 NX
Heart muscle	2 NX
Skin	0 NX

Enterocytes	42 NX
Small intestine	46 NX
Colon	42 NX
Rectum	36 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	57 NX
Pancreas	57 NX

Extravillous trophoblasts	43 NX
Placenta	43 NX

Fibroblasts	23 NX
Prostate	109 NX
Placenta	38 NX
Lung	23 NX
Heart muscle	5 NX
Skin	0 NX

Glandular cells	89 NX
Prostate	89 NX

Granulocytes	45 NX
Colon	64 NX
Lung	26 NX

Hepatocytes	43 NX
Liver	43 NX

Hofbauer cells	41 NX
Placenta	41 NX

Horizontal cells	5 NX
Eye	5 NX

Intestinal endocrine cells	29 NX
Colon	31 NX
Rectum	28 NX

Ito cells	43 NX
Liver	43 NX

Kupffer cells	30 NX
Liver	30 NX

Late spermatids	22 NX
Testis	22 NX

Leydig cells	25 NX
Testis	25 NX

Macrophages	27 NX
Pancreas	61 NX
Kidney	50 NX
Prostate	36 NX
Testis	28 NX
Lung	24 NX
Skin	0 NX

Melanocytes	0 NX
Skin	0 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	72 NX
Pancreas	72 NX

Mucus-secreting cells	37 NX
Colon	69 NX
Small intestine	41 NX
Rectum	34 NX

Muller glia cells	20 NX
Eye	20 NX

Pancreatic endocrine cells	52 NX
Pancreas	52 NX

Paneth cells	43 NX
Small intestine	56 NX
Colon	43 NX
Rectum	35 NX

Peritubular cells	34 NX
Testis	34 NX

Proximal tubular cells	47 NX
Kidney	47 NX

Rod photoreceptor cells	16 NX
Eye	16 NX

Sertoli cells	26 NX
Testis	26 NX

Smooth muscle cells	1 NX
Pancreas	101 NX
Prostate	82 NX
Heart muscle	1 NX
Skin	0 NX

Spermatocytes	64 NX
Testis	64 NX

Spermatogonia	71 NX
Testis	71 NX

Suprabasal keratinocytes	0 NX
Skin	0 NX

Syncytiotrophoblasts	55 NX
Placenta	55 NX

T-cells	21 NX
Colon	52 NX
Prostate	35 NX
Kidney	31 NX
Liver	21 NX
Lung	20 NX
Skin	0 NX

Undifferentiated cells	35 NX
Colon	52 NX
Small intestine	38 NX
Rectum	32 NX

Urothelial cells	118 NX
Prostate	118 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.