Cell type atlas - RPL5 - The Human Protein Atlas

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RPL5

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPL5
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein L5
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Cancer-related genes Disease related genes Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	607 NX
Lung	607 NX

Alveolar cells type 2	849 NX
Lung	849 NX

B-cells	2690 NX
Liver	2922 NX
Kidney	2598 NX
Colon	1124 NX

Basal glandular cells	3541 NX
Prostate	3541 NX

Basal keratinocytes	2525 NX
Skin	2525 NX

Bipolar cells	317 NX
Eye	317 NX

Cardiomyocytes	352 NX
Heart muscle	352 NX

Cholangiocytes	1200 NX
Liver	1200 NX

Ciliated cells	675 NX
Lung	675 NX

Club cells	1190 NX
Lung	1190 NX

Collecting duct cells	391 NX
Kidney	391 NX

Cone photoreceptor cells	84 NX
Eye	84 NX

Cytotrophoblasts	2238 NX
Placenta	2238 NX

Distal tubular cells	1689 NX
Kidney	1689 NX

Ductal cells	1279 NX
Pancreas	1279 NX

Early spermatids	1160 NX
Testis	1160 NX

Endothelial cells	1644 NX
Prostate	2812 NX
Testis	2394 NX
Skin	1910 NX
Liver	1758 NX
Placenta	1644 NX
Pancreas	1046 NX
Eye	802 NX
Lung	595 NX
Heart muscle	201 NX

Enterocytes	564 NX
Small intestine	1056 NX
Colon	489 NX
Rectum	481 NX

Erythroid cells	537 NX
Liver	537 NX

Exocrine glandular cells	2339 NX
Pancreas	2339 NX

Extravillous trophoblasts	3531 NX
Placenta	3531 NX

Fibroblasts	1573 NX
Prostate	2048 NX
Placenta	1709 NX
Skin	1549 NX
Lung	1206 NX
Heart muscle	251 NX

Glandular cells	2536 NX
Prostate	2536 NX

Granulocytes	1003 NX
Lung	1197 NX
Colon	808 NX

Hepatocytes	856 NX
Liver	856 NX

Hofbauer cells	1298 NX
Placenta	1298 NX

Horizontal cells	138 NX
Eye	138 NX

Intestinal endocrine cells	1189 NX
Rectum	1535 NX
Colon	843 NX

Ito cells	1198 NX
Liver	1198 NX

Kupffer cells	1468 NX
Liver	1468 NX

Late spermatids	889 NX
Testis	889 NX

Leydig cells	2620 NX
Testis	2620 NX

Macrophages	1566 NX
Prostate	2732 NX
Testis	2690 NX
Skin	1851 NX
Kidney	1445 NX
Lung	861 NX
Pancreas	583 NX

Melanocytes	1335 NX
Skin	1335 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	1647 NX
Pancreas	1647 NX

Mucus-secreting cells	1586 NX
Rectum	2985 NX
Colon	1402 NX
Small intestine	1073 NX

Muller glia cells	343 NX
Eye	343 NX

Pancreatic endocrine cells	1936 NX
Pancreas	1936 NX

Paneth cells	1164 NX
Rectum	2557 NX
Small intestine	1164 NX
Colon	553 NX

Peritubular cells	2027 NX
Testis	2027 NX

Proximal tubular cells	1766 NX
Kidney	1766 NX

Rod photoreceptor cells	227 NX
Eye	227 NX

Sertoli cells	1035 NX
Testis	1035 NX

Smooth muscle cells	1886 NX
Prostate	2719 NX
Skin	2319 NX
Pancreas	1419 NX
Heart muscle	265 NX

Spermatocytes	532 NX
Testis	532 NX

Spermatogonia	457 NX
Testis	457 NX

Suprabasal keratinocytes	2529 NX
Skin	2529 NX

Syncytiotrophoblasts	2185 NX
Placenta	2185 NX

T-cells	1966 NX
Prostate	2493 NX
Kidney	2172 NX
Skin	1966 NX
Liver	1670 NX
Lung	1025 NX
Colon	959 NX

Undifferentiated cells	2488 NX
Rectum	2915 NX
Small intestine	2488 NX
Colon	1233 NX

Urothelial cells	3231 NX
Prostate	3231 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.