Cell type atlas - PANK3 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

PANK3

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	PANK3
Gene descriptionⁱ Full gene name according to HGNC.	Pantothenate kinase 3
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Enterocytes)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Enterocytes)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	24 NX
Lung	24 NX

Alveolar cells type 2	17 NX
Lung	17 NX

B-cells	17 NX
Colon	22 NX
Liver	20 NX
Kidney	9 NX

Basal glandular cells	19 NX
Prostate	19 NX

Basal keratinocytes	31 NX
Skin	31 NX

Bipolar cells	27 NX
Eye	27 NX

Cardiomyocytes	14 NX
Heart muscle	14 NX

Cholangiocytes	23 NX
Liver	23 NX

Ciliated cells	19 NX
Lung	19 NX

Club cells	17 NX
Lung	17 NX

Collecting duct cells	24 NX
Kidney	24 NX

Cone photoreceptor cells	26 NX
Eye	26 NX

Cytotrophoblasts	14 NX
Placenta	14 NX

Distal tubular cells	8 NX
Kidney	8 NX

Ductal cells	15 NX
Pancreas	15 NX

Early spermatids	10 NX
Testis	10 NX

Endothelial cells	23 NX
Prostate	43 NX
Skin	28 NX
Heart muscle	27 NX
Eye	26 NX
Placenta	23 NX
Liver	20 NX
Lung	18 NX
Testis	11 NX
Pancreas	7 NX

Enterocytes	101 NX
Rectum	118 NX
Small intestine	87 NX
Colon	85 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	18 NX
Pancreas	18 NX

Extravillous trophoblasts	12 NX
Placenta	12 NX

Fibroblasts	20 NX
Prostate	29 NX
Heart muscle	21 NX
Placenta	20 NX
Lung	20 NX
Skin	20 NX

Glandular cells	30 NX
Prostate	30 NX

Granulocytes	15 NX
Colon	18 NX
Lung	12 NX

Hepatocytes	79 NX
Liver	79 NX

Hofbauer cells	20 NX
Placenta	20 NX

Horizontal cells	27 NX
Eye	27 NX

Intestinal endocrine cells	33 NX
Rectum	35 NX
Colon	31 NX

Ito cells	18 NX
Liver	18 NX

Kupffer cells	27 NX
Liver	27 NX

Late spermatids	13 NX
Testis	13 NX

Leydig cells	16 NX
Testis	16 NX

Macrophages	19 NX
Testis	28 NX
Prostate	26 NX
Skin	23 NX
Kidney	20 NX
Lung	14 NX
Pancreas	9 NX

Melanocytes	22 NX
Skin	22 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	11 NX
Pancreas	11 NX

Mucus-secreting cells	33 NX
Rectum	43 NX
Small intestine	29 NX
Colon	26 NX

Muller glia cells	12 NX
Eye	12 NX

Pancreatic endocrine cells	19 NX
Pancreas	19 NX

Paneth cells	32 NX
Rectum	53 NX
Colon	32 NX
Small intestine	25 NX

Peritubular cells	17 NX
Testis	17 NX

Proximal tubular cells	20 NX
Kidney	20 NX

Rod photoreceptor cells	26 NX
Eye	26 NX

Sertoli cells	26 NX
Testis	26 NX

Smooth muscle cells	32 NX
Heart muscle	35 NX
Prostate	33 NX
Skin	21 NX
Pancreas	16 NX

Spermatocytes	26 NX
Testis	26 NX

Spermatogonia	27 NX
Testis	27 NX

Suprabasal keratinocytes	49 NX
Skin	49 NX

Syncytiotrophoblasts	35 NX
Placenta	35 NX

T-cells	10 NX
Prostate	31 NX
Colon	21 NX
Skin	13 NX
Lung	10 NX
Kidney	10 NX
Liver	8 NX

Undifferentiated cells	35 NX
Colon	54 NX
Rectum	45 NX
Small intestine	24 NX

Urothelial cells	45 NX
Prostate	45 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.