Cell type atlas - MRPL37 - The Human Protein Atlas

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MRPL37

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MRPL37
Gene descriptionⁱ Full gene name according to HGNC.	Mitochondrial ribosomal protein L37
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	21 NX
Lung	21 NX

Alveolar cells type 2	19 NX
Lung	19 NX

B-cells	21 NX
Liver	64 NX
Colon	24 NX
Kidney	18 NX

Basal glandular cells	37 NX
Prostate	37 NX

Basal keratinocytes	31 NX
Skin	31 NX

Bipolar cells	8 NX
Eye	8 NX

Cardiomyocytes	69 NX
Heart muscle	69 NX

Cholangiocytes	48 NX
Liver	48 NX

Ciliated cells	19 NX
Lung	19 NX

Club cells	17 NX
Lung	17 NX

Collecting duct cells	17 NX
Kidney	17 NX

Cone photoreceptor cells	2 NX
Eye	2 NX

Cytotrophoblasts	103 NX
Placenta	103 NX

Distal tubular cells	68 NX
Kidney	68 NX

Ductal cells	71 NX
Pancreas	71 NX

Early spermatids	26 NX
Testis	26 NX

Endothelial cells	28 NX
Pancreas	61 NX
Placenta	42 NX
Liver	34 NX
Skin	31 NX
Prostate	29 NX
Testis	28 NX
Heart muscle	22 NX
Eye	13 NX
Lung	12 NX

Enterocytes	48 NX
Small intestine	65 NX
Rectum	35 NX
Colon	26 NX

Erythroid cells	47 NX
Liver	47 NX

Exocrine glandular cells	84 NX
Pancreas	84 NX

Extravillous trophoblasts	119 NX
Placenta	119 NX

Fibroblasts	37 NX
Placenta	69 NX
Heart muscle	43 NX
Skin	27 NX
Lung	23 NX
Prostate	22 NX

Glandular cells	38 NX
Prostate	38 NX

Granulocytes	14 NX
Lung	19 NX
Colon	9 NX

Hepatocytes	149 NX
Liver	149 NX

Hofbauer cells	77 NX
Placenta	77 NX

Horizontal cells	6 NX
Eye	6 NX

Intestinal endocrine cells	32 NX
Rectum	47 NX
Colon	17 NX

Ito cells	38 NX
Liver	38 NX

Kupffer cells	36 NX
Liver	36 NX

Late spermatids	44 NX
Testis	44 NX

Leydig cells	24 NX
Testis	24 NX

Macrophages	28 NX
Pancreas	59 NX
Kidney	43 NX
Prostate	31 NX
Testis	26 NX
Lung	23 NX
Skin	20 NX

Melanocytes	22 NX
Skin	22 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	59 NX
Pancreas	59 NX

Mucus-secreting cells	48 NX
Rectum	62 NX
Small intestine	43 NX
Colon	35 NX

Muller glia cells	9 NX
Eye	9 NX

Pancreatic endocrine cells	62 NX
Pancreas	62 NX

Paneth cells	32 NX
Rectum	66 NX
Small intestine	32 NX
Colon	14 NX

Peritubular cells	27 NX
Testis	27 NX

Proximal tubular cells	83 NX
Kidney	83 NX

Rod photoreceptor cells	7 NX
Eye	7 NX

Sertoli cells	13 NX
Testis	13 NX

Smooth muscle cells	26 NX
Pancreas	102 NX
Prostate	30 NX
Heart muscle	26 NX
Skin	22 NX

Spermatocytes	22 NX
Testis	22 NX

Spermatogonia	38 NX
Testis	38 NX

Suprabasal keratinocytes	33 NX
Skin	33 NX

Syncytiotrophoblasts	62 NX
Placenta	62 NX

T-cells	26 NX
Liver	40 NX
Lung	26 NX
Kidney	26 NX
Colon	24 NX
Skin	21 NX
Prostate	18 NX

Undifferentiated cells	81 NX
Small intestine	92 NX
Rectum	77 NX
Colon	59 NX

Urothelial cells	44 NX
Prostate	44 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.