Cell type atlas - COX7A2L - The Human Protein Atlas

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COX7A2L

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	COX7A2L
Gene descriptionⁱ Full gene name according to HGNC.	Cytochrome c oxidase subunit 7A2 like
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	30 NX
Lung	30 NX

Alveolar cells type 2	61 NX
Lung	61 NX

B-cells	171 NX
Liver	187 NX
Kidney	160 NX
Colon	160 NX

Basal glandular cells	166 NX
Prostate	166 NX

Basal keratinocytes	236 NX
Skin	236 NX

Bipolar cells	116 NX
Eye	116 NX

Cardiomyocytes	141 NX
Heart muscle	141 NX

Cholangiocytes	133 NX
Liver	133 NX

Ciliated cells	96 NX
Lung	96 NX

Club cells	51 NX
Lung	51 NX

Collecting duct cells	141 NX
Kidney	141 NX

Cone photoreceptor cells	35 NX
Eye	35 NX

Cytotrophoblasts	190 NX
Placenta	190 NX

Distal tubular cells	547 NX
Kidney	547 NX

Ductal cells	206 NX
Pancreas	206 NX

Early spermatids	16 NX
Testis	16 NX

Endothelial cells	158 NX
Skin	212 NX
Placenta	172 NX
Prostate	171 NX
Testis	168 NX
Pancreas	158 NX
Heart muscle	106 NX
Liver	101 NX
Eye	98 NX
Lung	41 NX

Enterocytes	104 NX
Small intestine	201 NX
Rectum	100 NX
Colon	85 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	200 NX
Pancreas	200 NX

Extravillous trophoblasts	264 NX
Placenta	264 NX

Fibroblasts	167 NX
Skin	177 NX
Placenta	173 NX
Prostate	155 NX
Heart muscle	104 NX
Lung	51 NX

Glandular cells	185 NX
Prostate	185 NX

Granulocytes	86 NX
Colon	119 NX
Lung	54 NX

Hepatocytes	193 NX
Liver	193 NX

Hofbauer cells	205 NX
Placenta	205 NX

Horizontal cells	124 NX
Eye	124 NX

Intestinal endocrine cells	277 NX
Colon	292 NX
Rectum	262 NX

Ito cells	114 NX
Liver	114 NX

Kupffer cells	244 NX
Liver	244 NX

Late spermatids	18 NX
Testis	18 NX

Leydig cells	150 NX
Testis	150 NX

Macrophages	178 NX
Kidney	227 NX
Prostate	203 NX
Skin	190 NX
Testis	183 NX
Pancreas	157 NX
Lung	65 NX

Melanocytes	209 NX
Skin	209 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	288 NX
Pancreas	288 NX

Mucus-secreting cells	202 NX
Colon	351 NX
Rectum	196 NX
Small intestine	176 NX

Muller glia cells	183 NX
Eye	183 NX

Pancreatic endocrine cells	198 NX
Pancreas	198 NX

Paneth cells	161 NX
Rectum	197 NX
Small intestine	161 NX
Colon	112 NX

Peritubular cells	149 NX
Testis	149 NX

Proximal tubular cells	386 NX
Kidney	386 NX

Rod photoreceptor cells	96 NX
Eye	96 NX

Sertoli cells	110 NX
Testis	110 NX

Smooth muscle cells	206 NX
Pancreas	292 NX
Skin	222 NX
Prostate	179 NX
Heart muscle	108 NX

Spermatocytes	196 NX
Testis	196 NX

Spermatogonia	268 NX
Testis	268 NX

Suprabasal keratinocytes	215 NX
Skin	215 NX

Syncytiotrophoblasts	276 NX
Placenta	276 NX

T-cells	186 NX
Kidney	245 NX
Liver	197 NX
Skin	193 NX
Colon	148 NX
Prostate	118 NX
Lung	65 NX

Undifferentiated cells	235 NX
Colon	253 NX
Small intestine	203 NX
Rectum	195 NX

Urothelial cells	168 NX
Prostate	168 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.