Cell type atlas - GORASP2 - The Human Protein Atlas

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GORASP2

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	GORASP2
Gene descriptionⁱ Full gene name according to HGNC.	Golgi reassembly stacking protein 2
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	1

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Late spermatids)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Late spermatids)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	39 NX
Lung	39 NX

Alveolar cells type 2	30 NX
Lung	30 NX

B-cells	27 NX
Liver	63 NX
Kidney	27 NX
Colon	24 NX

Basal glandular cells	29 NX
Prostate	29 NX

Basal keratinocytes	33 NX
Skin	33 NX

Bipolar cells	32 NX
Eye	32 NX

Cardiomyocytes	35 NX
Heart muscle	35 NX

Cholangiocytes	23 NX
Liver	23 NX

Ciliated cells	15 NX
Lung	15 NX

Club cells	41 NX
Lung	41 NX

Collecting duct cells	19 NX
Kidney	19 NX

Cone photoreceptor cells	30 NX
Eye	30 NX

Cytotrophoblasts	97 NX
Placenta	97 NX

Distal tubular cells	48 NX
Kidney	48 NX

Ductal cells	54 NX
Pancreas	54 NX

Early spermatids	187 NX
Testis	187 NX

Endothelial cells	27 NX
Prostate	41 NX
Pancreas	39 NX
Testis	32 NX
Placenta	31 NX
Liver	27 NX
Skin	26 NX
Lung	23 NX
Heart muscle	20 NX
Eye	15 NX

Enterocytes	31 NX
Rectum	43 NX
Small intestine	29 NX
Colon	24 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	69 NX
Pancreas	69 NX

Extravillous trophoblasts	90 NX
Placenta	90 NX

Fibroblasts	49 NX
Placenta	73 NX
Prostate	52 NX
Heart muscle	45 NX
Skin	37 NX
Lung	18 NX

Glandular cells	42 NX
Prostate	42 NX

Granulocytes	20 NX
Lung	21 NX
Colon	18 NX

Hepatocytes	43 NX
Liver	43 NX

Hofbauer cells	42 NX
Placenta	42 NX

Horizontal cells	40 NX
Eye	40 NX

Intestinal endocrine cells	30 NX
Rectum	40 NX
Colon	20 NX

Ito cells	47 NX
Liver	47 NX

Kupffer cells	20 NX
Liver	20 NX

Late spermatids	276 NX
Testis	276 NX

Leydig cells	54 NX
Testis	54 NX

Macrophages	28 NX
Pancreas	35 NX
Lung	32 NX
Skin	28 NX
Testis	25 NX
Kidney	22 NX
Prostate	21 NX

Melanocytes	46 NX
Skin	46 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	59 NX
Pancreas	59 NX

Mucus-secreting cells	50 NX
Colon	75 NX
Rectum	51 NX
Small intestine	44 NX

Muller glia cells	31 NX
Eye	31 NX

Pancreatic endocrine cells	60 NX
Pancreas	60 NX

Paneth cells	39 NX
Rectum	47 NX
Small intestine	39 NX
Colon	29 NX

Peritubular cells	47 NX
Testis	47 NX

Proximal tubular cells	35 NX
Kidney	35 NX

Rod photoreceptor cells	30 NX
Eye	30 NX

Sertoli cells	58 NX
Testis	58 NX

Smooth muscle cells	34 NX
Pancreas	86 NX
Prostate	34 NX
Heart muscle	28 NX
Skin	28 NX

Spermatocytes	32 NX
Testis	32 NX

Spermatogonia	40 NX
Testis	40 NX

Suprabasal keratinocytes	32 NX
Skin	32 NX

Syncytiotrophoblasts	192 NX
Placenta	192 NX

T-cells	36 NX
Skin	44 NX
Kidney	43 NX
Liver	40 NX
Colon	36 NX
Prostate	35 NX
Lung	22 NX

Undifferentiated cells	43 NX
Colon	48 NX
Rectum	46 NX
Small intestine	39 NX

Urothelial cells	67 NX
Prostate	67 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.