Cell type atlas - SNX17 - The Human Protein Atlas

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SNX17

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	SNX17
Gene descriptionⁱ Full gene name according to HGNC.	Sorting nexin 17
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	15 NX
Lung	15 NX

Alveolar cells type 2	43 NX
Lung	43 NX

B-cells	74 NX
Kidney	89 NX
Liver	74 NX
Colon	60 NX

Basal glandular cells	35 NX
Prostate	35 NX

Basal keratinocytes	29 NX
Skin	29 NX

Bipolar cells	29 NX
Eye	29 NX

Cardiomyocytes	29 NX
Heart muscle	29 NX

Cholangiocytes	38 NX
Liver	38 NX

Ciliated cells	34 NX
Lung	34 NX

Club cells	23 NX
Lung	23 NX

Collecting duct cells	28 NX
Kidney	28 NX

Cone photoreceptor cells	14 NX
Eye	14 NX

Cytotrophoblasts	142 NX
Placenta	142 NX

Distal tubular cells	70 NX
Kidney	70 NX

Ductal cells	74 NX
Pancreas	74 NX

Early spermatids	7 NX
Testis	7 NX

Endothelial cells	38 NX
Pancreas	82 NX
Placenta	73 NX
Testis	59 NX
Eye	53 NX
Skin	45 NX
Prostate	33 NX
Lung	32 NX
Liver	32 NX
Heart muscle	24 NX

Enterocytes	56 NX
Small intestine	62 NX
Rectum	59 NX
Colon	43 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	56 NX
Pancreas	56 NX

Extravillous trophoblasts	114 NX
Placenta	114 NX

Fibroblasts	59 NX
Placenta	97 NX
Skin	56 NX
Prostate	37 NX
Lung	32 NX
Heart muscle	24 NX

Glandular cells	36 NX
Prostate	36 NX

Granulocytes	43 NX
Colon	55 NX
Lung	30 NX

Hepatocytes	51 NX
Liver	51 NX

Hofbauer cells	122 NX
Placenta	122 NX

Horizontal cells	43 NX
Eye	43 NX

Intestinal endocrine cells	53 NX
Colon	54 NX
Rectum	52 NX

Ito cells	38 NX
Liver	38 NX

Kupffer cells	114 NX
Liver	114 NX

Late spermatids	8 NX
Testis	8 NX

Leydig cells	54 NX
Testis	54 NX

Macrophages	76 NX
Pancreas	164 NX
Kidney	108 NX
Testis	80 NX
Prostate	73 NX
Skin	57 NX
Lung	56 NX

Melanocytes	66 NX
Skin	66 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	150 NX
Pancreas	150 NX

Mucus-secreting cells	43 NX
Small intestine	49 NX
Rectum	45 NX
Colon	36 NX

Muller glia cells	77 NX
Eye	77 NX

Pancreatic endocrine cells	55 NX
Pancreas	55 NX

Paneth cells	63 NX
Rectum	65 NX
Small intestine	63 NX
Colon	20 NX

Peritubular cells	80 NX
Testis	80 NX

Proximal tubular cells	75 NX
Kidney	75 NX

Rod photoreceptor cells	20 NX
Eye	20 NX

Sertoli cells	32 NX
Testis	32 NX

Smooth muscle cells	51 NX
Pancreas	117 NX
Skin	54 NX
Heart muscle	48 NX
Prostate	36 NX

Spermatocytes	59 NX
Testis	59 NX

Spermatogonia	50 NX
Testis	50 NX

Suprabasal keratinocytes	30 NX
Skin	30 NX

Syncytiotrophoblasts	83 NX
Placenta	83 NX

T-cells	86 NX
Kidney	104 NX
Liver	103 NX
Colon	62 NX
Skin	53 NX
Lung	40 NX
Prostate	31 NX

Undifferentiated cells	52 NX
Small intestine	59 NX
Rectum	51 NX
Colon	48 NX

Urothelial cells	27 NX
Prostate	27 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.