Cell type atlas - CCNG1 - The Human Protein Atlas

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CCNG1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CCNG1
Gene descriptionⁱ Full gene name according to HGNC.	Cyclin G1
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Cancer-related genes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	7

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	24 NX
Lung	24 NX

Alveolar cells type 2	18 NX
Lung	18 NX

B-cells	59 NX
Colon	85 NX
Kidney	80 NX
Liver	33 NX

Basal glandular cells	79 NX
Prostate	79 NX

Basal keratinocytes	51 NX
Skin	51 NX

Bipolar cells	12 NX
Eye	12 NX

Cardiomyocytes	41 NX
Heart muscle	41 NX

Cholangiocytes	31 NX
Liver	31 NX

Ciliated cells	3 NX
Lung	3 NX

Club cells	17 NX
Lung	17 NX

Collecting duct cells	35 NX
Kidney	35 NX

Cone photoreceptor cells	0 NX
Eye	0 NX

Cytotrophoblasts	122 NX
Placenta	122 NX

Distal tubular cells	138 NX
Kidney	138 NX

Ductal cells	62 NX
Pancreas	62 NX

Early spermatids	4 NX
Testis	4 NX

Endothelial cells	46 NX
Prostate	67 NX
Testis	61 NX
Placenta	53 NX
Liver	52 NX
Skin	52 NX
Lung	26 NX
Heart muscle	23 NX
Eye	23 NX
Pancreas	18 NX

Enterocytes	56 NX
Small intestine	150 NX
Rectum	53 NX
Colon	23 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	103 NX
Pancreas	103 NX

Extravillous trophoblasts	86 NX
Placenta	86 NX

Fibroblasts	67 NX
Placenta	80 NX
Skin	76 NX
Prostate	54 NX
Heart muscle	43 NX
Lung	39 NX

Glandular cells	99 NX
Prostate	99 NX

Granulocytes	43 NX
Colon	46 NX
Lung	40 NX

Hepatocytes	41 NX
Liver	41 NX

Hofbauer cells	51 NX
Placenta	51 NX

Horizontal cells	14 NX
Eye	14 NX

Intestinal endocrine cells	68 NX
Colon	92 NX
Rectum	45 NX

Ito cells	60 NX
Liver	60 NX

Kupffer cells	65 NX
Liver	65 NX

Late spermatids	3 NX
Testis	3 NX

Leydig cells	70 NX
Testis	70 NX

Macrophages	48 NX
Prostate	77 NX
Skin	59 NX
Testis	48 NX
Kidney	48 NX
Lung	19 NX
Pancreas	16 NX

Melanocytes	35 NX
Skin	35 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	51 NX
Pancreas	51 NX

Mucus-secreting cells	100 NX
Rectum	152 NX
Small intestine	92 NX
Colon	64 NX

Muller glia cells	23 NX
Eye	23 NX

Pancreatic endocrine cells	103 NX
Pancreas	102 NX

Paneth cells	63 NX
Rectum	139 NX
Small intestine	63 NX
Colon	17 NX

Peritubular cells	68 NX
Testis	68 NX

Proximal tubular cells	185 NX
Kidney	185 NX

Rod photoreceptor cells	9 NX
Eye	9 NX

Sertoli cells	39 NX
Testis	39 NX

Smooth muscle cells	60 NX
Prostate	78 NX
Skin	72 NX
Pancreas	48 NX
Heart muscle	46 NX

Spermatocytes	7 NX
Testis	7 NX

Spermatogonia	13 NX
Testis	13 NX

Suprabasal keratinocytes	39 NX
Skin	39 NX

Syncytiotrophoblasts	81 NX
Placenta	81 NX

T-cells	89 NX
Prostate	135 NX
Colon	106 NX
Kidney	106 NX
Skin	89 NX
Liver	76 NX
Lung	20 NX

Undifferentiated cells	180 NX
Small intestine	199 NX
Rectum	164 NX
Colon	124 NX

Urothelial cells	82 NX
Prostate	82 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.