Cell type atlas - COL4A3BP - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

COL4A3BP

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	COL4A3BP
Gene descriptionⁱ Full gene name according to HGNC.	Collagen type IV alpha 3 binding protein
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	21

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (ASC diff, WM-115)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	57 NX
Lung	57 NX

Alveolar cells type 2	59 NX
Lung	58 NX

B-cells	6 NX
Colon	22 NX
Kidney	9 NX
Liver	2 NX

Basal glandular cells	28 NX
Prostate	28 NX

Basal keratinocytes	17 NX
Skin	17 NX

Bipolar cells	31 NX
Eye	31 NX

Cardiomyocytes	33 NX
Heart muscle	33 NX

Cholangiocytes	23 NX
Liver	23 NX

Ciliated cells	71 NX
Lung	71 NX

Club cells	75 NX
Lung	75 NX

Collecting duct cells	17 NX
Kidney	17 NX

Cone photoreceptor cells	22 NX
Eye	22 NX

Cytotrophoblasts	14 NX
Placenta	14 NX

Distal tubular cells	18 NX
Kidney	18 NX

Ductal cells	20 NX
Pancreas	20 NX

Early spermatids	83 NX
Testis	83 NX

Endothelial cells	28 NX
Lung	61 NX
Heart muscle	55 NX
Eye	35 NX
Testis	31 NX
Prostate	24 NX
Skin	24 NX
Liver	20 NX
Pancreas	18 NX
Placenta	17 NX

Enterocytes	19 NX
Rectum	25 NX
Small intestine	23 NX
Colon	14 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	19 NX
Pancreas	19 NX

Extravillous trophoblasts	14 NX
Placenta	14 NX

Fibroblasts	21 NX
Heart muscle	41 NX
Lung	40 NX
Prostate	29 NX
Skin	24 NX
Placenta	16 NX

Glandular cells	36 NX
Prostate	36 NX

Granulocytes	48 NX
Lung	67 NX
Colon	28 NX

Hepatocytes	18 NX
Liver	18 NX

Hofbauer cells	32 NX
Placenta	32 NX

Horizontal cells	41 NX
Eye	41 NX

Intestinal endocrine cells	26 NX
Colon	34 NX
Rectum	19 NX

Ito cells	56 NX
Liver	56 NX

Kupffer cells	33 NX
Liver	33 NX

Late spermatids	73 NX
Testis	73 NX

Leydig cells	32 NX
Testis	32 NX

Macrophages	37 NX
Lung	94 NX
Kidney	56 NX
Prostate	44 NX
Pancreas	30 NX
Skin	26 NX
Testis	23 NX

Melanocytes	49 NX
Skin	49 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	20 NX
Pancreas	20 NX

Mucus-secreting cells	16 NX
Small intestine	17 NX
Rectum	16 NX
Colon	12 NX

Muller glia cells	31 NX
Eye	31 NX

Pancreatic endocrine cells	22 NX
Pancreas	21 NX

Paneth cells	13 NX
Colon	23 NX
Rectum	13 NX
Small intestine	11 NX

Peritubular cells	39 NX
Testis	39 NX

Proximal tubular cells	22 NX
Kidney	22 NX

Rod photoreceptor cells	33 NX
Eye	33 NX

Sertoli cells	19 NX
Testis	19 NX

Smooth muscle cells	20 NX
Heart muscle	55 NX
Prostate	22 NX
Skin	19 NX
Pancreas	12 NX

Spermatocytes	42 NX
Testis	42 NX

Spermatogonia	32 NX
Testis	32 NX

Suprabasal keratinocytes	23 NX
Skin	23 NX

Syncytiotrophoblasts	23 NX
Placenta	23 NX

T-cells	21 NX
Lung	30 NX
Colon	27 NX
Prostate	22 NX
Skin	22 NX
Kidney	17 NX
Liver	16 NX

Undifferentiated cells	14 NX
Rectum	15 NX
Small intestine	14 NX
Colon	6 NX

Urothelial cells	38 NX
Prostate	38 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.