Cell type atlas - SLC39A7 - The Human Protein Atlas

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SLC39A7

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	SLC39A7
Gene descriptionⁱ Full gene name according to HGNC.	Solute carrier family 39 member 7
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Transporters
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	24 NX
Lung	24 NX

Alveolar cells type 2	33 NX
Lung	33 NX

B-cells	15 NX
Liver	35 NX
Colon	15 NX
Kidney	13 NX

Basal glandular cells	26 NX
Prostate	26 NX

Basal keratinocytes	32 NX
Skin	32 NX

Bipolar cells	27 NX
Eye	27 NX

Cardiomyocytes	30 NX
Heart muscle	30 NX

Cholangiocytes	28 NX
Liver	28 NX

Ciliated cells	23 NX
Lung	23 NX

Club cells	33 NX
Lung	33 NX

Collecting duct cells	24 NX
Kidney	24 NX

Cone photoreceptor cells	28 NX
Eye	28 NX

Cytotrophoblasts	88 NX
Placenta	88 NX

Distal tubular cells	5 NX
Kidney	5 NX

Ductal cells	61 NX
Pancreas	61 NX

Early spermatids	1 NX
Testis	1 NX

Endothelial cells	34 NX
Pancreas	82 NX
Prostate	47 NX
Placenta	40 NX
Eye	39 NX
Skin	34 NX
Liver	34 NX
Lung	32 NX
Testis	28 NX
Heart muscle	25 NX

Enterocytes	63 NX
Colon	74 NX
Rectum	68 NX
Small intestine	44 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	75 NX
Pancreas	75 NX

Extravillous trophoblasts	114 NX
Placenta	114 NX

Fibroblasts	62 NX
Placenta	83 NX
Skin	72 NX
Prostate	63 NX
Lung	43 NX
Heart muscle	32 NX

Glandular cells	56 NX
Prostate	56 NX

Granulocytes	20 NX
Lung	30 NX
Colon	9 NX

Hepatocytes	31 NX
Liver	31 NX

Hofbauer cells	39 NX
Placenta	39 NX

Horizontal cells	11 NX
Eye	11 NX

Intestinal endocrine cells	24 NX
Rectum	35 NX
Colon	14 NX

Ito cells	29 NX
Liver	29 NX

Kupffer cells	17 NX
Liver	17 NX

Late spermatids	2 NX
Testis	2 NX

Leydig cells	43 NX
Testis	43 NX

Macrophages	24 NX
Pancreas	56 NX
Skin	31 NX
Lung	21 NX
Kidney	18 NX
Testis	14 NX
Prostate	13 NX

Melanocytes	39 NX
Skin	39 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	28 NX
Pancreas	28 NX

Mucus-secreting cells	109 NX
Colon	184 NX
Small intestine	96 NX
Rectum	91 NX

Muller glia cells	41 NX
Eye	41 NX

Pancreatic endocrine cells	56 NX
Pancreas	56 NX

Paneth cells	56 NX
Colon	63 NX
Rectum	56 NX
Small intestine	28 NX

Peritubular cells	40 NX
Testis	40 NX

Proximal tubular cells	20 NX
Kidney	20 NX

Rod photoreceptor cells	22 NX
Eye	22 NX

Sertoli cells	19 NX
Testis	19 NX

Smooth muscle cells	34 NX
Pancreas	87 NX
Prostate	34 NX
Skin	34 NX
Heart muscle	26 NX

Spermatocytes	8 NX
Testis	8 NX

Spermatogonia	11 NX
Testis	11 NX

Suprabasal keratinocytes	36 NX
Skin	36 NX

Syncytiotrophoblasts	141 NX
Placenta	141 NX

T-cells	27 NX
Lung	33 NX
Skin	31 NX
Kidney	30 NX
Liver	26 NX
Prostate	22 NX
Colon	18 NX

Undifferentiated cells	54 NX
Colon	66 NX
Rectum	54 NX
Small intestine	38 NX

Urothelial cells	34 NX
Prostate	34 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.