Cell type atlas - RNF167 - The Human Protein Atlas

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RNF167

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RNF167
Gene descriptionⁱ Full gene name according to HGNC.	Ring finger protein 167
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular,Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	10

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	0 NX
Lung	0 NX

Alveolar cells type 2	4 NX
Lung	4 NX

B-cells	38 NX
Kidney	76 NX
Liver	31 NX
Colon	28 NX

Basal glandular cells	33 NX
Prostate	33 NX

Basal keratinocytes	61 NX
Skin	61 NX

Bipolar cells	41 NX
Eye	41 NX

Cardiomyocytes	13 NX
Heart muscle	13 NX

Cholangiocytes	66 NX
Liver	66 NX

Ciliated cells	3 NX
Lung	3 NX

Club cells	2 NX
Lung	2 NX

Collecting duct cells	47 NX
Kidney	47 NX

Cone photoreceptor cells	20 NX
Eye	20 NX

Cytotrophoblasts	102 NX
Placenta	102 NX

Distal tubular cells	48 NX
Kidney	48 NX

Ductal cells	69 NX
Pancreas	68 NX

Early spermatids	41 NX
Testis	41 NX

Endothelial cells	36 NX
Placenta	57 NX
Liver	47 NX
Testis	46 NX
Skin	44 NX
Pancreas	36 NX
Eye	26 NX
Prostate	25 NX
Heart muscle	11 NX
Lung	6 NX

Enterocytes	73 NX
Small intestine	96 NX
Colon	60 NX
Rectum	58 NX

Erythroid cells	47 NX
Liver	47 NX

Exocrine glandular cells	58 NX
Pancreas	58 NX

Extravillous trophoblasts	102 NX
Placenta	102 NX

Fibroblasts	40 NX
Placenta	59 NX
Skin	40 NX
Prostate	20 NX
Heart muscle	12 NX
Lung	6 NX

Glandular cells	31 NX
Prostate	31 NX

Granulocytes	14 NX
Colon	18 NX
Lung	9 NX

Hepatocytes	84 NX
Liver	84 NX

Hofbauer cells	52 NX
Placenta	52 NX

Horizontal cells	18 NX
Eye	18 NX

Intestinal endocrine cells	31 NX
Rectum	31 NX
Colon	31 NX

Ito cells	38 NX
Liver	38 NX

Kupffer cells	36 NX
Liver	36 NX

Late spermatids	69 NX
Testis	69 NX

Leydig cells	45 NX
Testis	45 NX

Macrophages	42 NX
Kidney	64 NX
Prostate	48 NX
Testis	47 NX
Pancreas	44 NX
Skin	38 NX
Lung	5 NX

Melanocytes	37 NX
Skin	37 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	58 NX
Pancreas	58 NX

Mucus-secreting cells	40 NX
Small intestine	45 NX
Rectum	42 NX
Colon	38 NX

Muller glia cells	45 NX
Eye	45 NX

Pancreatic endocrine cells	53 NX
Pancreas	53 NX

Paneth cells	40 NX
Rectum	43 NX
Colon	40 NX
Small intestine	39 NX

Peritubular cells	51 NX
Testis	51 NX

Proximal tubular cells	53 NX
Kidney	53 NX

Rod photoreceptor cells	26 NX
Eye	26 NX

Sertoli cells	39 NX
Testis	39 NX

Smooth muscle cells	28 NX
Prostate	38 NX
Skin	35 NX
Pancreas	28 NX
Heart muscle	12 NX

Spermatocytes	111 NX
Testis	111 NX

Spermatogonia	84 NX
Testis	84 NX

Suprabasal keratinocytes	73 NX
Skin	73 NX

Syncytiotrophoblasts	105 NX
Placenta	105 NX

T-cells	90 NX
Kidney	117 NX
Liver	107 NX
Skin	79 NX
Colon	74 NX
Prostate	22 NX
Lung	14 NX

Undifferentiated cells	54 NX
Colon	55 NX
Rectum	54 NX
Small intestine	54 NX

Urothelial cells	39 NX
Prostate	39 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.