Cell type atlas - RPL28 - The Human Protein Atlas

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RPL28

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPL28
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein L28
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	9

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	292 NX
Lung	292 NX

Alveolar cells type 2	451 NX
Lung	451 NX

B-cells	5533 NX
Liver	5981 NX
Kidney	5636 NX
Colon	1634 NX

Basal glandular cells	3560 NX
Prostate	3560 NX

Basal keratinocytes	3364 NX
Skin	3364 NX

Bipolar cells	265 NX
Eye	265 NX

Cardiomyocytes	143 NX
Heart muscle	143 NX

Cholangiocytes	1745 NX
Liver	1745 NX

Ciliated cells	448 NX
Lung	448 NX

Club cells	753 NX
Lung	753 NX

Collecting duct cells	1106 NX
Kidney	1106 NX

Cone photoreceptor cells	153 NX
Eye	153 NX

Cytotrophoblasts	2958 NX
Placenta	2958 NX

Distal tubular cells	2162 NX
Kidney	2162 NX

Ductal cells	2047 NX
Pancreas	2047 NX

Early spermatids	1155 NX
Testis	1155 NX

Endothelial cells	2504 NX
Prostate	4235 NX
Testis	3497 NX
Placenta	2962 NX
Skin	2628 NX
Liver	2504 NX
Pancreas	1400 NX
Eye	1275 NX
Lung	397 NX
Heart muscle	86 NX

Enterocytes	2388 NX
Small intestine	3808 NX
Colon	2101 NX
Rectum	1758 NX

Erythroid cells	1308 NX
Liver	1308 NX

Exocrine glandular cells	3802 NX
Pancreas	3802 NX

Extravillous trophoblasts	5038 NX
Placenta	5038 NX

Fibroblasts	2290 NX
Placenta	3326 NX
Skin	2271 NX
Prostate	2116 NX
Lung	1124 NX
Heart muscle	112 NX

Glandular cells	3624 NX
Prostate	3624 NX

Granulocytes	840 NX
Colon	964 NX
Lung	716 NX

Hepatocytes	2219 NX
Liver	2219 NX

Hofbauer cells	3594 NX
Placenta	3594 NX

Horizontal cells	170 NX
Eye	170 NX

Intestinal endocrine cells	2198 NX
Rectum	3221 NX
Colon	1176 NX

Ito cells	2535 NX
Liver	2535 NX

Kupffer cells	5085 NX
Liver	5085 NX

Late spermatids	2613 NX
Testis	2612 NX

Leydig cells	3193 NX
Testis	3193 NX

Macrophages	4690 NX
Prostate	6015 NX
Kidney	5604 NX
Testis	5593 NX
Skin	4690 NX
Pancreas	1780 NX
Lung	1090 NX

Melanocytes	2006 NX
Skin	2006 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	3397 NX
Pancreas	3397 NX

Mucus-secreting cells	4331 NX
Rectum	6465 NX
Small intestine	3999 NX
Colon	2590 NX

Muller glia cells	519 NX
Eye	519 NX

Pancreatic endocrine cells	4111 NX
Pancreas	4111 NX

Paneth cells	3700 NX
Rectum	5237 NX
Small intestine	3700 NX
Colon	2522 NX

Peritubular cells	1545 NX
Testis	1545 NX

Proximal tubular cells	2485 NX
Kidney	2485 NX

Rod photoreceptor cells	344 NX
Eye	344 NX

Sertoli cells	957 NX
Testis	957 NX

Smooth muscle cells	2029 NX
Pancreas	2990 NX
Prostate	2255 NX
Skin	1958 NX
Heart muscle	86 NX

Spermatocytes	825 NX
Testis	825 NX

Spermatogonia	973 NX
Testis	973 NX

Suprabasal keratinocytes	4287 NX
Skin	4287 NX

Syncytiotrophoblasts	2831 NX
Placenta	2831 NX

T-cells	4026 NX
Skin	6989 NX
Kidney	5404 NX
Liver	4458 NX
Prostate	3513 NX
Colon	1435 NX
Lung	1156 NX

Undifferentiated cells	5879 NX
Rectum	6293 NX
Small intestine	5929 NX
Colon	1828 NX

Urothelial cells	5549 NX
Prostate	5549 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.