Cell type atlas - PHF14 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

PHF14

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	PHF14
Gene descriptionⁱ Full gene name according to HGNC.	PHD finger protein 14
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	39 NX
Lung	39 NX

Alveolar cells type 2	35 NX
Lung	35 NX

B-cells	49 NX
Colon	61 NX
Kidney	54 NX
Liver	43 NX

Basal glandular cells	63 NX
Prostate	63 NX

Basal keratinocytes	51 NX
Skin	51 NX

Bipolar cells	78 NX
Eye	78 NX

Cardiomyocytes	19 NX
Heart muscle	19 NX

Cholangiocytes	31 NX
Liver	31 NX

Ciliated cells	36 NX
Lung	36 NX

Club cells	53 NX
Lung	53 NX

Collecting duct cells	31 NX
Kidney	31 NX

Cone photoreceptor cells	55 NX
Eye	55 NX

Cytotrophoblasts	58 NX
Placenta	58 NX

Distal tubular cells	23 NX
Kidney	23 NX

Ductal cells	78 NX
Pancreas	78 NX

Early spermatids	18 NX
Testis	18 NX

Endothelial cells	70 NX
Pancreas	93 NX
Testis	87 NX
Prostate	78 NX
Placenta	71 NX
Liver	70 NX
Skin	69 NX
Lung	47 NX
Heart muscle	45 NX
Eye	32 NX

Enterocytes	43 NX
Colon	51 NX
Small intestine	41 NX
Rectum	30 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	73 NX
Pancreas	73 NX

Extravillous trophoblasts	66 NX
Placenta	66 NX

Fibroblasts	61 NX
Prostate	69 NX
Lung	66 NX
Placenta	62 NX
Skin	46 NX
Heart muscle	36 NX

Glandular cells	44 NX
Prostate	44 NX

Granulocytes	56 NX
Colon	83 NX
Lung	30 NX

Hepatocytes	39 NX
Liver	39 NX

Hofbauer cells	36 NX
Placenta	36 NX

Horizontal cells	75 NX
Eye	75 NX

Intestinal endocrine cells	89 NX
Colon	95 NX
Rectum	82 NX

Ito cells	59 NX
Liver	59 NX

Kupffer cells	36 NX
Liver	36 NX

Late spermatids	10 NX
Testis	9 NX

Leydig cells	95 NX
Testis	95 NX

Macrophages	36 NX
Testis	56 NX
Pancreas	42 NX
Kidney	38 NX
Skin	36 NX
Lung	31 NX
Prostate	23 NX

Melanocytes	35 NX
Skin	35 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	31 NX
Pancreas	31 NX

Mucus-secreting cells	60 NX
Colon	77 NX
Rectum	59 NX
Small intestine	57 NX

Muller glia cells	50 NX
Eye	50 NX

Pancreatic endocrine cells	75 NX
Pancreas	75 NX

Paneth cells	42 NX
Rectum	51 NX
Small intestine	42 NX
Colon	32 NX

Peritubular cells	110 NX
Testis	110 NX

Proximal tubular cells	27 NX
Kidney	27 NX

Rod photoreceptor cells	64 NX
Eye	64 NX

Sertoli cells	52 NX
Testis	52 NX

Smooth muscle cells	48 NX
Prostate	57 NX
Skin	49 NX
Pancreas	48 NX
Heart muscle	26 NX

Spermatocytes	134 NX
Testis	134 NX

Spermatogonia	124 NX
Testis	124 NX

Suprabasal keratinocytes	46 NX
Skin	46 NX

Syncytiotrophoblasts	33 NX
Placenta	33 NX

T-cells	31 NX
Kidney	67 NX
Colon	64 NX
Liver	44 NX
Skin	30 NX
Lung	25 NX
Prostate	22 NX

Undifferentiated cells	60 NX
Colon	72 NX
Small intestine	65 NX
Rectum	47 NX

Urothelial cells	47 NX
Prostate	47 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.