Cell type atlas - RPL18A - The Human Protein Atlas

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RPL18A

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPL18A
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein L18a
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	482 NX
Lung	482 NX

Alveolar cells type 2	927 NX
Lung	927 NX

B-cells	6414 NX
Kidney	8483 NX
Liver	6414 NX
Colon	1540 NX

Basal glandular cells	4901 NX
Prostate	4901 NX

Basal keratinocytes	7713 NX
Skin	7713 NX

Bipolar cells	240 NX
Eye	240 NX

Cardiomyocytes	390 NX
Heart muscle	390 NX

Cholangiocytes	1829 NX
Liver	1829 NX

Ciliated cells	614 NX
Lung	614 NX

Club cells	1163 NX
Lung	1163 NX

Collecting duct cells	876 NX
Kidney	876 NX

Cone photoreceptor cells	120 NX
Eye	120 NX

Cytotrophoblasts	4309 NX
Placenta	4309 NX

Distal tubular cells	2023 NX
Kidney	2023 NX

Ductal cells	2829 NX
Pancreas	2829 NX

Early spermatids	40 NX
Testis	40 NX

Endothelial cells	2920 NX
Skin	6161 NX
Prostate	5913 NX
Testis	3593 NX
Placenta	3322 NX
Liver	2920 NX
Pancreas	2077 NX
Eye	941 NX
Lung	723 NX
Heart muscle	450 NX

Enterocytes	1767 NX
Small intestine	2364 NX
Colon	1592 NX
Rectum	1009 NX

Erythroid cells	1098 NX
Liver	1098 NX

Exocrine glandular cells	7784 NX
Pancreas	7784 NX

Extravillous trophoblasts	7255 NX
Placenta	7255 NX

Fibroblasts	3472 NX
Skin	4070 NX
Placenta	3273 NX
Prostate	2789 NX
Lung	2192 NX
Heart muscle	550 NX

Glandular cells	4168 NX
Prostate	4168 NX

Granulocytes	1383 NX
Lung	1839 NX
Colon	927 NX

Hepatocytes	2046 NX
Liver	2046 NX

Hofbauer cells	2961 NX
Placenta	2961 NX

Horizontal cells	124 NX
Eye	124 NX

Intestinal endocrine cells	1773 NX
Rectum	2472 NX
Colon	1074 NX

Ito cells	2332 NX
Liver	2332 NX

Kupffer cells	4202 NX
Liver	4202 NX

Late spermatids	100 NX
Testis	100 NX

Leydig cells	3857 NX
Testis	3857 NX

Macrophages	5200 NX
Skin	6625 NX
Prostate	5759 NX
Testis	5638 NX
Kidney	4962 NX
Pancreas	1479 NX
Lung	1348 NX

Melanocytes	4503 NX
Skin	4503 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	5217 NX
Pancreas	5217 NX

Mucus-secreting cells	3612 NX
Rectum	4832 NX
Small intestine	3231 NX
Colon	2393 NX

Muller glia cells	347 NX
Eye	347 NX

Pancreatic endocrine cells	5814 NX
Pancreas	5814 NX

Paneth cells	2767 NX
Rectum	4184 NX
Small intestine	2767 NX
Colon	1581 NX

Peritubular cells	1530 NX
Testis	1530 NX

Proximal tubular cells	2592 NX
Kidney	2592 NX

Rod photoreceptor cells	348 NX
Eye	348 NX

Sertoli cells	1235 NX
Testis	1235 NX

Smooth muscle cells	4176 NX
Skin	4760 NX
Prostate	4176 NX
Pancreas	2912 NX
Heart muscle	566 NX

Spermatocytes	139 NX
Testis	139 NX

Spermatogonia	662 NX
Testis	662 NX

Suprabasal keratinocytes	9734 NX
Skin	9734 NX

Syncytiotrophoblasts	3897 NX
Placenta	3897 NX

T-cells	4323 NX
Skin	7458 NX
Kidney	5706 NX
Prostate	4323 NX
Liver	3850 NX
Lung	1963 NX
Colon	1215 NX

Undifferentiated cells	4713 NX
Small intestine	5646 NX
Rectum	4713 NX
Colon	1738 NX

Urothelial cells	6202 NX
Prostate	6202 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.