Cell type atlas - RAB11A - The Human Protein Atlas

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RAB11A

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RAB11A
Gene descriptionⁱ Full gene name according to HGNC.	RAB11A, member RAS oncogene family
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	6

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Syncytiotrophoblasts)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Syncytiotrophoblasts)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	54 NX
Lung	54 NX

Alveolar cells type 2	56 NX
Lung	56 NX

B-cells	74 NX
Kidney	111 NX
Colon	91 NX
Liver	53 NX

Basal glandular cells	139 NX
Prostate	139 NX

Basal keratinocytes	171 NX
Skin	171 NX

Bipolar cells	41 NX
Eye	41 NX

Cardiomyocytes	79 NX
Heart muscle	79 NX

Cholangiocytes	110 NX
Liver	110 NX

Ciliated cells	122 NX
Lung	122 NX

Club cells	60 NX
Lung	60 NX

Collecting duct cells	178 NX
Kidney	178 NX

Cone photoreceptor cells	31 NX
Eye	31 NX

Cytotrophoblasts	273 NX
Placenta	272 NX

Distal tubular cells	293 NX
Kidney	293 NX

Ductal cells	293 NX
Pancreas	293 NX

Early spermatids	267 NX
Testis	267 NX

Endothelial cells	253 NX
Placenta	450 NX
Skin	336 NX
Liver	290 NX
Testis	271 NX
Prostate	255 NX
Lung	251 NX
Pancreas	226 NX
Heart muscle	190 NX
Eye	89 NX

Enterocytes	196 NX
Colon	315 NX
Rectum	248 NX
Small intestine	177 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	300 NX
Pancreas	300 NX

Extravillous trophoblasts	259 NX
Placenta	259 NX

Fibroblasts	118 NX
Placenta	141 NX
Prostate	118 NX
Skin	111 NX
Lung	75 NX
Heart muscle	72 NX

Glandular cells	164 NX
Prostate	164 NX

Granulocytes	75 NX
Colon	110 NX
Lung	40 NX

Hepatocytes	76 NX
Liver	76 NX

Hofbauer cells	203 NX
Placenta	203 NX

Horizontal cells	54 NX
Eye	54 NX

Intestinal endocrine cells	198 NX
Colon	241 NX
Rectum	155 NX

Ito cells	220 NX
Liver	220 NX

Kupffer cells	109 NX
Liver	109 NX

Late spermatids	45 NX
Testis	45 NX

Leydig cells	90 NX
Testis	90 NX

Macrophages	142 NX
Skin	188 NX
Kidney	169 NX
Pancreas	166 NX
Testis	117 NX
Prostate	99 NX
Lung	71 NX

Melanocytes	177 NX
Skin	177 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	290 NX
Pancreas	290 NX

Mucus-secreting cells	193 NX
Colon	257 NX
Rectum	187 NX
Small intestine	172 NX

Muller glia cells	96 NX
Eye	96 NX

Pancreatic endocrine cells	319 NX
Pancreas	319 NX

Paneth cells	180 NX
Colon	389 NX
Rectum	180 NX
Small intestine	175 NX

Peritubular cells	81 NX
Testis	81 NX

Proximal tubular cells	213 NX
Kidney	213 NX

Rod photoreceptor cells	31 NX
Eye	31 NX

Sertoli cells	45 NX
Testis	45 NX

Smooth muscle cells	81 NX
Pancreas	150 NX
Skin	92 NX
Prostate	73 NX
Heart muscle	73 NX

Spermatocytes	257 NX
Testis	257 NX

Spermatogonia	104 NX
Testis	104 NX

Suprabasal keratinocytes	249 NX
Skin	249 NX

Syncytiotrophoblasts	811 NX
Placenta	811 NX

T-cells	71 NX
Skin	208 NX
Kidney	117 NX
Colon	78 NX
Lung	69 NX
Liver	66 NX
Prostate	65 NX

Undifferentiated cells	153 NX
Colon	279 NX
Rectum	153 NX
Small intestine	140 NX

Urothelial cells	293 NX
Prostate	293 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.