Cell type atlas - PSMD7 - The Human Protein Atlas

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PSMD7

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	PSMD7
Gene descriptionⁱ Full gene name according to HGNC.	Proteasome 26S subunit, non-ATPase 7
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Syncytiotrophoblasts)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Syncytiotrophoblasts)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	63 NX
Lung	63 NX

Alveolar cells type 2	54 NX
Lung	54 NX

B-cells	81 NX
Liver	108 NX
Kidney	89 NX
Colon	73 NX

Basal glandular cells	136 NX
Prostate	136 NX

Basal keratinocytes	93 NX
Skin	93 NX

Bipolar cells	51 NX
Eye	51 NX

Cardiomyocytes	46 NX
Heart muscle	46 NX

Cholangiocytes	64 NX
Liver	64 NX

Ciliated cells	86 NX
Lung	86 NX

Club cells	83 NX
Lung	83 NX

Collecting duct cells	44 NX
Kidney	44 NX

Cone photoreceptor cells	8 NX
Eye	8 NX

Cytotrophoblasts	286 NX
Placenta	286 NX

Distal tubular cells	68 NX
Kidney	68 NX

Ductal cells	119 NX
Pancreas	119 NX

Early spermatids	93 NX
Testis	93 NX

Endothelial cells	69 NX
Pancreas	208 NX
Prostate	187 NX
Placenta	96 NX
Lung	76 NX
Testis	69 NX
Liver	67 NX
Skin	66 NX
Eye	65 NX
Heart muscle	25 NX

Enterocytes	94 NX
Colon	118 NX
Small intestine	79 NX
Rectum	72 NX

Erythroid cells	70 NX
Liver	70 NX

Exocrine glandular cells	165 NX
Pancreas	165 NX

Extravillous trophoblasts	181 NX
Placenta	181 NX

Fibroblasts	80 NX
Prostate	201 NX
Placenta	112 NX
Lung	80 NX
Skin	70 NX
Heart muscle	25 NX

Glandular cells	157 NX
Prostate	157 NX

Granulocytes	102 NX
Colon	110 NX
Lung	93 NX

Hepatocytes	127 NX
Liver	127 NX

Hofbauer cells	168 NX
Placenta	168 NX

Horizontal cells	54 NX
Eye	54 NX

Intestinal endocrine cells	82 NX
Colon	99 NX
Rectum	66 NX

Ito cells	72 NX
Liver	72 NX

Kupffer cells	72 NX
Liver	72 NX

Late spermatids	15 NX
Testis	15 NX

Leydig cells	52 NX
Testis	52 NX

Macrophages	111 NX
Lung	135 NX
Pancreas	126 NX
Prostate	123 NX
Kidney	98 NX
Testis	87 NX
Skin	82 NX

Melanocytes	95 NX
Skin	95 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	142 NX
Pancreas	142 NX

Mucus-secreting cells	72 NX
Colon	124 NX
Small intestine	69 NX
Rectum	68 NX

Muller glia cells	65 NX
Eye	65 NX

Pancreatic endocrine cells	137 NX
Pancreas	137 NX

Paneth cells	88 NX
Colon	121 NX
Small intestine	88 NX
Rectum	73 NX

Peritubular cells	62 NX
Testis	62 NX

Proximal tubular cells	80 NX
Kidney	80 NX

Rod photoreceptor cells	48 NX
Eye	48 NX

Sertoli cells	91 NX
Testis	91 NX

Smooth muscle cells	77 NX
Pancreas	197 NX
Prostate	174 NX
Skin	75 NX
Heart muscle	26 NX

Spermatocytes	113 NX
Testis	113 NX

Spermatogonia	95 NX
Testis	95 NX

Suprabasal keratinocytes	113 NX
Skin	113 NX

Syncytiotrophoblasts	499 NX
Placenta	499 NX

T-cells	83 NX
Colon	104 NX
Lung	98 NX
Skin	96 NX
Prostate	83 NX
Kidney	75 NX
Liver	72 NX

Undifferentiated cells	83 NX
Colon	156 NX
Rectum	77 NX
Small intestine	72 NX

Urothelial cells	181 NX
Prostate	181 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.