Cell type atlas - DNAJC3 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

DNAJC3

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	DNAJC3
Gene descriptionⁱ Full gene name according to HGNC.	DnaJ heat shock protein family (Hsp40) member C3
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	75 NX
Lung	75 NX

Alveolar cells type 2	59 NX
Lung	59 NX

B-cells	48 NX
Liver	92 NX
Colon	54 NX
Kidney	22 NX

Basal glandular cells	70 NX
Prostate	70 NX

Basal keratinocytes	84 NX
Skin	84 NX

Bipolar cells	22 NX
Eye	22 NX

Cardiomyocytes	45 NX
Heart muscle	45 NX

Cholangiocytes	71 NX
Liver	71 NX

Ciliated cells	64 NX
Lung	64 NX

Club cells	57 NX
Lung	57 NX

Collecting duct cells	45 NX
Kidney	45 NX

Cone photoreceptor cells	26 NX
Eye	26 NX

Cytotrophoblasts	47 NX
Placenta	47 NX

Distal tubular cells	18 NX
Kidney	18 NX

Ductal cells	88 NX
Pancreas	88 NX

Early spermatids	152 NX
Testis	152 NX

Endothelial cells	55 NX
Prostate	90 NX
Heart muscle	89 NX
Skin	71 NX
Lung	55 NX
Pancreas	50 NX
Liver	49 NX
Testis	49 NX
Placenta	47 NX
Eye	40 NX

Enterocytes	53 NX
Rectum	64 NX
Colon	54 NX
Small intestine	50 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	104 NX
Pancreas	104 NX

Extravillous trophoblasts	112 NX
Placenta	112 NX

Fibroblasts	93 NX
Prostate	215 NX
Heart muscle	115 NX
Skin	114 NX
Placenta	52 NX
Lung	47 NX

Glandular cells	145 NX
Prostate	145 NX

Granulocytes	66 NX
Lung	67 NX
Colon	64 NX

Hepatocytes	125 NX
Liver	125 NX

Hofbauer cells	73 NX
Placenta	73 NX

Horizontal cells	24 NX
Eye	24 NX

Intestinal endocrine cells	40 NX
Colon	48 NX
Rectum	33 NX

Ito cells	63 NX
Liver	63 NX

Kupffer cells	61 NX
Liver	61 NX

Late spermatids	22 NX
Testis	22 NX

Leydig cells	66 NX
Testis	66 NX

Macrophages	82 NX
Pancreas	131 NX
Prostate	112 NX
Skin	89 NX
Lung	76 NX
Testis	60 NX
Kidney	58 NX

Melanocytes	113 NX
Skin	113 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	51 NX
Pancreas	51 NX

Mucus-secreting cells	45 NX
Colon	140 NX
Rectum	40 NX
Small intestine	36 NX

Muller glia cells	44 NX
Eye	44 NX

Pancreatic endocrine cells	88 NX
Pancreas	88 NX

Paneth cells	42 NX
Colon	60 NX
Rectum	42 NX
Small intestine	39 NX

Peritubular cells	71 NX
Testis	71 NX

Proximal tubular cells	58 NX
Kidney	58 NX

Rod photoreceptor cells	17 NX
Eye	17 NX

Sertoli cells	91 NX
Testis	91 NX

Smooth muscle cells	89 NX
Heart muscle	154 NX
Prostate	98 NX
Skin	88 NX
Pancreas	86 NX

Spermatocytes	34 NX
Testis	34 NX

Spermatogonia	81 NX
Testis	81 NX

Suprabasal keratinocytes	81 NX
Skin	81 NX

Syncytiotrophoblasts	159 NX
Placenta	159 NX

T-cells	52 NX
Prostate	109 NX
Skin	88 NX
Colon	84 NX
Lung	63 NX
Kidney	52 NX
Liver	44 NX

Undifferentiated cells	37 NX
Colon	90 NX
Rectum	37 NX
Small intestine	33 NX

Urothelial cells	100 NX
Prostate	100 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.