Cell type atlas - RBM3 - The Human Protein Atlas

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RBM3

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RBM3
Gene descriptionⁱ Full gene name according to HGNC.	RNA binding motif protein 3
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Exocrine glandular cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Exocrine glandular cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	155 NX
Lung	155 NX

Alveolar cells type 2	140 NX
Lung	140 NX

B-cells	318 NX
Colon	370 NX
Liver	343 NX
Kidney	223 NX

Basal glandular cells	135 NX
Prostate	135 NX

Basal keratinocytes	462 NX
Skin	462 NX

Bipolar cells	61 NX
Eye	60 NX

Cardiomyocytes	71 NX
Heart muscle	71 NX

Cholangiocytes	115 NX
Liver	115 NX

Ciliated cells	91 NX
Lung	91 NX

Club cells	154 NX
Lung	154 NX

Collecting duct cells	51 NX
Kidney	51 NX

Cone photoreceptor cells	45 NX
Eye	45 NX

Cytotrophoblasts	435 NX
Placenta	435 NX

Distal tubular cells	149 NX
Kidney	149 NX

Ductal cells	259 NX
Pancreas	259 NX

Early spermatids	5 NX
Testis	5 NX

Endothelial cells	223 NX
Skin	718 NX
Pancreas	448 NX
Placenta	330 NX
Lung	242 NX
Testis	223 NX
Eye	180 NX
Liver	148 NX
Prostate	137 NX
Heart muscle	126 NX

Enterocytes	137 NX
Colon	172 NX
Small intestine	104 NX
Rectum	97 NX

Erythroid cells	70 NX
Liver	70 NX

Exocrine glandular cells	1251 NX
Pancreas	1251 NX

Extravillous trophoblasts	595 NX
Placenta	595 NX

Fibroblasts	406 NX
Skin	562 NX
Placenta	399 NX
Lung	307 NX
Prostate	111 NX
Heart muscle	96 NX

Glandular cells	86 NX
Prostate	86 NX

Granulocytes	256 NX
Lung	300 NX
Colon	211 NX

Hepatocytes	72 NX
Liver	72 NX

Hofbauer cells	382 NX
Placenta	382 NX

Horizontal cells	40 NX
Eye	40 NX

Intestinal endocrine cells	237 NX
Colon	292 NX
Rectum	183 NX

Ito cells	174 NX
Liver	174 NX

Kupffer cells	455 NX
Liver	455 NX

Late spermatids	11 NX
Testis	11 NX

Leydig cells	228 NX
Testis	228 NX

Macrophages	402 NX
Skin	685 NX
Testis	417 NX
Pancreas	410 NX
Prostate	342 NX
Kidney	327 NX
Lung	309 NX

Melanocytes	496 NX
Skin	496 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	551 NX
Pancreas	551 NX

Mucus-secreting cells	244 NX
Colon	513 NX
Rectum	268 NX
Small intestine	161 NX

Muller glia cells	125 NX
Eye	125 NX

Pancreatic endocrine cells	636 NX
Pancreas	636 NX

Paneth cells	225 NX
Rectum	241 NX
Small intestine	225 NX
Colon	176 NX

Peritubular cells	139 NX
Testis	139 NX

Proximal tubular cells	114 NX
Kidney	114 NX

Rod photoreceptor cells	76 NX
Eye	76 NX

Sertoli cells	129 NX
Testis	129 NX

Smooth muscle cells	466 NX
Skin	593 NX
Pancreas	466 NX
Prostate	256 NX
Heart muscle	127 NX

Spermatocytes	26 NX
Testis	26 NX

Spermatogonia	175 NX
Testis	175 NX

Suprabasal keratinocytes	444 NX
Skin	444 NX

Syncytiotrophoblasts	409 NX
Placenta	409 NX

T-cells	335 NX
Skin	564 NX
Lung	342 NX
Liver	338 NX
Colon	292 NX
Kidney	267 NX
Prostate	140 NX

Undifferentiated cells	294 NX
Colon	407 NX
Small intestine	293 NX
Rectum	285 NX

Urothelial cells	177 NX
Prostate	177 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.