Cell type atlas - CDS2 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CDS2

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CDS2
Gene descriptionⁱ Full gene name according to HGNC.	CDP-diacylglycerol synthase 2
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (U-266/84)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	18 NX
Lung	18 NX

Alveolar cells type 2	15 NX
Lung	15 NX

B-cells	31 NX
Kidney	40 NX
Colon	33 NX
Liver	21 NX

Basal glandular cells	26 NX
Prostate	26 NX

Basal keratinocytes	16 NX
Skin	16 NX

Bipolar cells	61 NX
Eye	61 NX

Cardiomyocytes	46 NX
Heart muscle	46 NX

Cholangiocytes	26 NX
Liver	26 NX

Ciliated cells	9 NX
Lung	9 NX

Club cells	11 NX
Lung	11 NX

Collecting duct cells	31 NX
Kidney	31 NX

Cone photoreceptor cells	90 NX
Eye	90 NX

Cytotrophoblasts	19 NX
Placenta	19 NX

Distal tubular cells	5 NX
Kidney	5 NX

Ductal cells	29 NX
Pancreas	29 NX

Early spermatids	55 NX
Testis	55 NX

Endothelial cells	33 NX
Heart muscle	72 NX
Prostate	50 NX
Eye	40 NX
Skin	33 NX
Pancreas	32 NX
Testis	29 NX
Placenta	25 NX
Lung	20 NX
Liver	18 NX

Enterocytes	12 NX
Rectum	17 NX
Small intestine	13 NX
Colon	10 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	20 NX
Pancreas	20 NX

Extravillous trophoblasts	30 NX
Placenta	30 NX

Fibroblasts	16 NX
Skin	19 NX
Prostate	17 NX
Heart muscle	16 NX
Placenta	15 NX
Lung	10 NX

Glandular cells	18 NX
Prostate	18 NX

Granulocytes	21 NX
Colon	28 NX
Lung	14 NX

Hepatocytes	18 NX
Liver	18 NX

Hofbauer cells	51 NX
Placenta	51 NX

Horizontal cells	41 NX
Eye	41 NX

Intestinal endocrine cells	10 NX
Colon	14 NX
Rectum	7 NX

Ito cells	27 NX
Liver	27 NX

Kupffer cells	37 NX
Liver	37 NX

Late spermatids	25 NX
Testis	25 NX

Leydig cells	15 NX
Testis	15 NX

Macrophages	23 NX
Pancreas	40 NX
Prostate	32 NX
Skin	26 NX
Kidney	23 NX
Testis	23 NX
Lung	14 NX

Melanocytes	30 NX
Skin	30 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	29 NX
Pancreas	29 NX

Mucus-secreting cells	12 NX
Small intestine	16 NX
Rectum	12 NX
Colon	9 NX

Muller glia cells	22 NX
Eye	22 NX

Pancreatic endocrine cells	26 NX
Pancreas	26 NX

Paneth cells	15 NX
Small intestine	39 NX
Rectum	15 NX
Colon	3 NX

Peritubular cells	23 NX
Testis	23 NX

Proximal tubular cells	14 NX
Kidney	14 NX

Rod photoreceptor cells	59 NX
Eye	59 NX

Sertoli cells	19 NX
Testis	19 NX

Smooth muscle cells	54 NX
Heart muscle	101 NX
Skin	56 NX
Prostate	37 NX
Pancreas	19 NX

Spermatocytes	22 NX
Testis	22 NX

Spermatogonia	30 NX
Testis	30 NX

Suprabasal keratinocytes	13 NX
Skin	13 NX

Syncytiotrophoblasts	14 NX
Placenta	14 NX

T-cells	30 NX
Skin	43 NX
Kidney	40 NX
Colon	30 NX
Liver	29 NX
Prostate	26 NX
Lung	19 NX

Undifferentiated cells	13 NX
Rectum	15 NX
Small intestine	12 NX
Colon	9 NX

Urothelial cells	27 NX
Prostate	27 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.