Cell type atlas - PSMA7 - The Human Protein Atlas

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PSMA7

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	PSMA7
Gene descriptionⁱ Full gene name according to HGNC.	Proteasome subunit alpha 7
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	197 NX
Lung	197 NX

Alveolar cells type 2	155 NX
Lung	155 NX

B-cells	252 NX
Liver	431 NX
Kidney	299 NX
Colon	206 NX

Basal glandular cells	304 NX
Prostate	304 NX

Basal keratinocytes	333 NX
Skin	333 NX

Bipolar cells	127 NX
Eye	126 NX

Cardiomyocytes	268 NX
Heart muscle	268 NX

Cholangiocytes	364 NX
Liver	364 NX

Ciliated cells	245 NX
Lung	245 NX

Club cells	226 NX
Lung	226 NX

Collecting duct cells	244 NX
Kidney	244 NX

Cone photoreceptor cells	69 NX
Eye	69 NX

Cytotrophoblasts	588 NX
Placenta	588 NX

Distal tubular cells	423 NX
Kidney	423 NX

Ductal cells	493 NX
Pancreas	493 NX

Early spermatids	257 NX
Testis	257 NX

Endothelial cells	316 NX
Pancreas	698 NX
Prostate	619 NX
Placenta	512 NX
Liver	420 NX
Skin	318 NX
Lung	306 NX
Testis	292 NX
Heart muscle	268 NX
Eye	264 NX

Enterocytes	331 NX
Colon	352 NX
Small intestine	335 NX
Rectum	238 NX

Erythroid cells	350 NX
Liver	350 NX

Exocrine glandular cells	631 NX
Pancreas	631 NX

Extravillous trophoblasts	671 NX
Placenta	671 NX

Fibroblasts	333 NX
Prostate	491 NX
Placenta	384 NX
Heart muscle	308 NX
Lung	303 NX
Skin	282 NX

Glandular cells	338 NX
Prostate	338 NX

Granulocytes	243 NX
Lung	274 NX
Colon	211 NX

Hepatocytes	717 NX
Liver	717 NX

Hofbauer cells	719 NX
Placenta	718 NX

Horizontal cells	78 NX
Eye	78 NX

Intestinal endocrine cells	223 NX
Colon	265 NX
Rectum	180 NX

Ito cells	353 NX
Liver	353 NX

Kupffer cells	445 NX
Liver	445 NX

Late spermatids	113 NX
Testis	113 NX

Leydig cells	310 NX
Testis	310 NX

Macrophages	461 NX
Pancreas	672 NX
Lung	647 NX
Kidney	586 NX
Prostate	488 NX
Testis	434 NX
Skin	404 NX

Melanocytes	349 NX
Skin	349 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	628 NX
Pancreas	628 NX

Mucus-secreting cells	200 NX
Colon	446 NX
Small intestine	217 NX
Rectum	174 NX

Muller glia cells	170 NX
Eye	170 NX

Pancreatic endocrine cells	556 NX
Pancreas	556 NX

Paneth cells	260 NX
Colon	553 NX
Small intestine	260 NX
Rectum	225 NX

Peritubular cells	276 NX
Testis	276 NX

Proximal tubular cells	528 NX
Kidney	528 NX

Rod photoreceptor cells	96 NX
Eye	96 NX

Sertoli cells	226 NX
Testis	226 NX

Smooth muscle cells	368 NX
Pancreas	737 NX
Prostate	436 NX
Heart muscle	368 NX
Skin	310 NX

Spermatocytes	74 NX
Testis	74 NX

Spermatogonia	148 NX
Testis	148 NX

Suprabasal keratinocytes	270 NX
Skin	270 NX

Syncytiotrophoblasts	713 NX
Placenta	713 NX

T-cells	269 NX
Kidney	421 NX
Skin	401 NX
Lung	380 NX
Colon	269 NX
Liver	240 NX
Prostate	231 NX

Undifferentiated cells	303 NX
Colon	425 NX
Small intestine	309 NX
Rectum	242 NX

Urothelial cells	319 NX
Prostate	319 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.