Cell type atlas - OCEL1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

OCEL1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	OCEL1
Gene descriptionⁱ Full gene name according to HGNC.	Occludin/ELL domain containing 1
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	7

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Proximal tubular cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (ASC diff)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Proximal tubular cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	12 NX
Lung	12 NX

Alveolar cells type 2	5 NX
Lung	5 NX

B-cells	15 NX
Kidney	27 NX
Colon	16 NX
Liver	14 NX

Basal glandular cells	24 NX
Prostate	24 NX

Basal keratinocytes	6 NX
Skin	6 NX

Bipolar cells	12 NX
Eye	12 NX

Cardiomyocytes	6 NX
Heart muscle	6 NX

Cholangiocytes	31 NX
Liver	31 NX

Ciliated cells	63 NX
Lung	63 NX

Club cells	8 NX
Lung	8 NX

Collecting duct cells	19 NX
Kidney	19 NX

Cone photoreceptor cells	2 NX
Eye	2 NX

Cytotrophoblasts	36 NX
Placenta	35 NX

Distal tubular cells	51 NX
Kidney	51 NX

Ductal cells	17 NX
Pancreas	17 NX

Early spermatids	4 NX
Testis	4 NX

Endothelial cells	15 NX
Lung	23 NX
Pancreas	22 NX
Placenta	20 NX
Liver	20 NX
Testis	19 NX
Eye	15 NX
Prostate	13 NX
Skin	10 NX
Heart muscle	6 NX

Enterocytes	74 NX
Small intestine	102 NX
Rectum	58 NX
Colon	41 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	24 NX
Pancreas	24 NX

Extravillous trophoblasts	36 NX
Placenta	36 NX

Fibroblasts	18 NX
Placenta	20 NX
Skin	17 NX
Prostate	16 NX
Heart muscle	11 NX
Lung	7 NX

Glandular cells	27 NX
Prostate	27 NX

Granulocytes	16 NX
Colon	28 NX
Lung	5 NX

Hepatocytes	76 NX
Liver	76 NX

Hofbauer cells	24 NX
Placenta	23 NX

Horizontal cells	24 NX
Eye	24 NX

Intestinal endocrine cells	17 NX
Colon	17 NX
Rectum	16 NX

Ito cells	22 NX
Liver	22 NX

Kupffer cells	20 NX
Liver	20 NX

Late spermatids	12 NX
Testis	12 NX

Leydig cells	26 NX
Testis	26 NX

Macrophages	17 NX
Kidney	36 NX
Prostate	26 NX
Testis	21 NX
Pancreas	21 NX
Lung	11 NX
Skin	10 NX

Melanocytes	15 NX
Skin	15 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	11 NX
Pancreas	11 NX

Mucus-secreting cells	30 NX
Small intestine	49 NX
Colon	40 NX
Rectum	29 NX

Muller glia cells	29 NX
Eye	29 NX

Pancreatic endocrine cells	21 NX
Pancreas	21 NX

Paneth cells	49 NX
Colon	101 NX
Small intestine	49 NX
Rectum	31 NX

Peritubular cells	22 NX
Testis	22 NX

Proximal tubular cells	113 NX
Kidney	113 NX

Rod photoreceptor cells	8 NX
Eye	8 NX

Sertoli cells	32 NX
Testis	32 NX

Smooth muscle cells	13 NX
Prostate	19 NX
Skin	15 NX
Pancreas	13 NX
Heart muscle	12 NX

Spermatocytes	8 NX
Testis	8 NX

Spermatogonia	14 NX
Testis	14 NX

Suprabasal keratinocytes	6 NX
Skin	6 NX

Syncytiotrophoblasts	86 NX
Placenta	86 NX

T-cells	20 NX
Prostate	35 NX
Kidney	24 NX
Colon	20 NX
Liver	19 NX
Skin	10 NX
Lung	9 NX

Undifferentiated cells	26 NX
Rectum	30 NX
Colon	26 NX
Small intestine	21 NX

Urothelial cells	18 NX
Prostate	18 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.