Cell type atlas - DNAJB11 - The Human Protein Atlas

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DNAJB11

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	DNAJB11
Gene descriptionⁱ Full gene name according to HGNC.	DnaJ heat shock protein family (Hsp40) member B11
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	18 NX
Lung	18 NX

Alveolar cells type 2	18 NX
Lung	18 NX

B-cells	40 NX
Liver	142 NX
Colon	67 NX
Kidney	13 NX

Basal glandular cells	176 NX
Prostate	176 NX

Basal keratinocytes	129 NX
Skin	129 NX

Bipolar cells	22 NX
Eye	22 NX

Cardiomyocytes	133 NX
Heart muscle	133 NX

Cholangiocytes	74 NX
Liver	74 NX

Ciliated cells	15 NX
Lung	15 NX

Club cells	22 NX
Lung	22 NX

Collecting duct cells	14 NX
Kidney	14 NX

Cone photoreceptor cells	18 NX
Eye	18 NX

Cytotrophoblasts	81 NX
Placenta	81 NX

Distal tubular cells	3 NX
Kidney	3 NX

Ductal cells	87 NX
Pancreas	87 NX

Early spermatids	28 NX
Testis	28 NX

Endothelial cells	75 NX
Prostate	130 NX
Placenta	88 NX
Heart muscle	82 NX
Pancreas	75 NX
Skin	67 NX
Eye	46 NX
Liver	38 NX
Testis	32 NX
Lung	20 NX

Enterocytes	82 NX
Colon	124 NX
Small intestine	61 NX
Rectum	40 NX

Erythroid cells	47 NX
Liver	47 NX

Exocrine glandular cells	75 NX
Pancreas	75 NX

Extravillous trophoblasts	136 NX
Placenta	136 NX

Fibroblasts	70 NX
Prostate	148 NX
Placenta	90 NX
Heart muscle	86 NX
Skin	66 NX
Lung	35 NX

Glandular cells	91 NX
Prostate	91 NX

Granulocytes	55 NX
Colon	92 NX
Lung	19 NX

Hepatocytes	86 NX
Liver	86 NX

Hofbauer cells	132 NX
Placenta	132 NX

Horizontal cells	22 NX
Eye	22 NX

Intestinal endocrine cells	136 NX
Colon	228 NX
Rectum	45 NX

Ito cells	66 NX
Liver	66 NX

Kupffer cells	76 NX
Liver	76 NX

Late spermatids	7 NX
Testis	7 NX

Leydig cells	29 NX
Testis	29 NX

Macrophages	64 NX
Prostate	136 NX
Skin	103 NX
Pancreas	103 NX
Testis	44 NX
Lung	35 NX
Kidney	35 NX

Melanocytes	98 NX
Skin	98 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	21 NX
Pancreas	21 NX

Mucus-secreting cells	38 NX
Colon	243 NX
Rectum	36 NX
Small intestine	36 NX

Muller glia cells	45 NX
Eye	45 NX

Pancreatic endocrine cells	81 NX
Pancreas	81 NX

Paneth cells	44 NX
Colon	150 NX
Rectum	44 NX
Small intestine	42 NX

Peritubular cells	24 NX
Testis	24 NX

Proximal tubular cells	17 NX
Kidney	17 NX

Rod photoreceptor cells	21 NX
Eye	21 NX

Sertoli cells	65 NX
Testis	65 NX

Smooth muscle cells	67 NX
Pancreas	150 NX
Heart muscle	75 NX
Prostate	67 NX
Skin	51 NX

Spermatocytes	102 NX
Testis	102 NX

Spermatogonia	78 NX
Testis	78 NX

Suprabasal keratinocytes	98 NX
Skin	98 NX

Syncytiotrophoblasts	163 NX
Placenta	163 NX

T-cells	65 NX
Prostate	148 NX
Colon	83 NX
Skin	76 NX
Liver	61 NX
Kidney	43 NX
Lung	25 NX

Undifferentiated cells	43 NX
Colon	174 NX
Small intestine	43 NX
Rectum	38 NX

Urothelial cells	144 NX
Prostate	144 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.