Cell type atlas - DDX24 - The Human Protein Atlas

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DDX24

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	DDX24
Gene descriptionⁱ Full gene name according to HGNC.	DEAD-box helicase 24
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	6

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	158 NX
Lung	158 NX

Alveolar cells type 2	152 NX
Lung	152 NX

B-cells	176 NX
Kidney	205 NX
Colon	184 NX
Liver	146 NX

Basal glandular cells	121 NX
Prostate	121 NX

Basal keratinocytes	162 NX
Skin	162 NX

Bipolar cells	169 NX
Eye	169 NX

Cardiomyocytes	198 NX
Heart muscle	198 NX

Cholangiocytes	59 NX
Liver	59 NX

Ciliated cells	193 NX
Lung	193 NX

Club cells	155 NX
Lung	155 NX

Collecting duct cells	140 NX
Kidney	140 NX

Cone photoreceptor cells	124 NX
Eye	124 NX

Cytotrophoblasts	77 NX
Placenta	76 NX

Distal tubular cells	231 NX
Kidney	231 NX

Ductal cells	124 NX
Pancreas	124 NX

Early spermatids	64 NX
Testis	64 NX

Endothelial cells	107 NX
Lung	190 NX
Eye	176 NX
Testis	154 NX
Heart muscle	138 NX
Prostate	132 NX
Skin	102 NX
Liver	101 NX
Placenta	97 NX
Pancreas	86 NX

Enterocytes	66 NX
Colon	76 NX
Small intestine	65 NX
Rectum	39 NX

Erythroid cells	117 NX
Liver	117 NX

Exocrine glandular cells	86 NX
Pancreas	86 NX

Extravillous trophoblasts	60 NX
Placenta	60 NX

Fibroblasts	133 NX
Prostate	272 NX
Lung	231 NX
Heart muscle	219 NX
Skin	143 NX
Placenta	73 NX

Glandular cells	81 NX
Prostate	81 NX

Granulocytes	147 NX
Lung	212 NX
Colon	83 NX

Hepatocytes	96 NX
Liver	96 NX

Hofbauer cells	75 NX
Placenta	75 NX

Horizontal cells	219 NX
Eye	219 NX

Intestinal endocrine cells	94 NX
Colon	105 NX
Rectum	82 NX

Ito cells	105 NX
Liver	105 NX

Kupffer cells	83 NX
Liver	83 NX

Late spermatids	47 NX
Testis	47 NX

Leydig cells	214 NX
Testis	214 NX

Macrophages	119 NX
Lung	191 NX
Skin	124 NX
Testis	122 NX
Kidney	117 NX
Prostate	104 NX
Pancreas	94 NX

Melanocytes	95 NX
Skin	95 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	181 NX
Pancreas	181 NX

Mucus-secreting cells	58 NX
Colon	120 NX
Small intestine	61 NX
Rectum	54 NX

Muller glia cells	131 NX
Eye	131 NX

Pancreatic endocrine cells	82 NX
Pancreas	82 NX

Paneth cells	69 NX
Small intestine	70 NX
Colon	69 NX
Rectum	44 NX

Peritubular cells	230 NX
Testis	230 NX

Proximal tubular cells	135 NX
Kidney	135 NX

Rod photoreceptor cells	190 NX
Eye	190 NX

Sertoli cells	162 NX
Testis	162 NX

Smooth muscle cells	157 NX
Prostate	209 NX
Heart muscle	206 NX
Skin	147 NX
Pancreas	95 NX

Spermatocytes	383 NX
Testis	383 NX

Spermatogonia	396 NX
Testis	396 NX

Suprabasal keratinocytes	127 NX
Skin	127 NX

Syncytiotrophoblasts	131 NX
Placenta	131 NX

T-cells	217 NX
Colon	362 NX
Skin	279 NX
Prostate	279 NX
Kidney	269 NX
Lung	217 NX
Liver	109 NX

Undifferentiated cells	55 NX
Colon	89 NX
Rectum	55 NX
Small intestine	45 NX

Urothelial cells	94 NX
Prostate	94 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.