Cell type atlas - ERP29 - The Human Protein Atlas

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ERP29

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	ERP29
Gene descriptionⁱ Full gene name according to HGNC.	Endoplasmic reticulum protein 29
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	4

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	77 NX
Lung	77 NX

Alveolar cells type 2	153 NX
Lung	153 NX

B-cells	312 NX
Kidney	348 NX
Liver	336 NX
Colon	276 NX

Basal glandular cells	160 NX
Prostate	160 NX

Basal keratinocytes	126 NX
Skin	126 NX

Bipolar cells	118 NX
Eye	118 NX

Cardiomyocytes	82 NX
Heart muscle	82 NX

Cholangiocytes	201 NX
Liver	201 NX

Ciliated cells	108 NX
Lung	108 NX

Club cells	83 NX
Lung	83 NX

Collecting duct cells	176 NX
Kidney	176 NX

Cone photoreceptor cells	104 NX
Eye	104 NX

Cytotrophoblasts	416 NX
Placenta	416 NX

Distal tubular cells	80 NX
Kidney	80 NX

Ductal cells	182 NX
Pancreas	182 NX

Early spermatids	5 NX
Testis	5 NX

Endothelial cells	100 NX
Placenta	190 NX
Testis	167 NX
Skin	141 NX
Eye	110 NX
Prostate	100 NX
Pancreas	82 NX
Liver	81 NX
Lung	58 NX
Heart muscle	58 NX

Enterocytes	239 NX
Small intestine	292 NX
Colon	221 NX
Rectum	165 NX

Erythroid cells	47 NX
Liver	47 NX

Exocrine glandular cells	186 NX
Pancreas	186 NX

Extravillous trophoblasts	319 NX
Placenta	319 NX

Fibroblasts	107 NX
Placenta	187 NX
Skin	106 NX
Prostate	93 NX
Heart muscle	70 NX
Lung	46 NX

Glandular cells	200 NX
Prostate	200 NX

Granulocytes	88 NX
Colon	110 NX
Lung	65 NX

Hepatocytes	289 NX
Liver	289 NX

Hofbauer cells	332 NX
Placenta	332 NX

Horizontal cells	76 NX
Eye	76 NX

Intestinal endocrine cells	190 NX
Colon	228 NX
Rectum	152 NX

Ito cells	118 NX
Liver	118 NX

Kupffer cells	288 NX
Liver	288 NX

Late spermatids	12 NX
Testis	12 NX

Leydig cells	119 NX
Testis	119 NX

Macrophages	207 NX
Prostate	341 NX
Kidney	252 NX
Pancreas	234 NX
Testis	217 NX
Skin	180 NX
Lung	160 NX

Melanocytes	160 NX
Skin	160 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	143 NX
Pancreas	143 NX

Mucus-secreting cells	208 NX
Colon	328 NX
Small intestine	231 NX
Rectum	187 NX

Muller glia cells	130 NX
Eye	130 NX

Pancreatic endocrine cells	147 NX
Pancreas	147 NX

Paneth cells	274 NX
Colon	276 NX
Small intestine	274 NX
Rectum	231 NX

Peritubular cells	100 NX
Testis	100 NX

Proximal tubular cells	214 NX
Kidney	214 NX

Rod photoreceptor cells	151 NX
Eye	151 NX

Sertoli cells	52 NX
Testis	52 NX

Smooth muscle cells	107 NX
Pancreas	155 NX
Prostate	109 NX
Skin	99 NX
Heart muscle	84 NX

Spermatocytes	40 NX
Testis	40 NX

Spermatogonia	200 NX
Testis	200 NX

Suprabasal keratinocytes	141 NX
Skin	141 NX

Syncytiotrophoblasts	369 NX
Placenta	369 NX

T-cells	228 NX
Kidney	291 NX
Colon	237 NX
Skin	229 NX
Prostate	214 NX
Liver	187 NX
Lung	105 NX

Undifferentiated cells	248 NX
Colon	289 NX
Small intestine	251 NX
Rectum	205 NX

Urothelial cells	181 NX
Prostate	181 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.