Cell type atlas - RPL6 - The Human Protein Atlas

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RPL6

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPL6
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein L6
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	8

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	742 NX
Lung	742 NX

Alveolar cells type 2	1203 NX
Lung	1203 NX

B-cells	3177 NX
Kidney	3302 NX
Liver	3177 NX
Colon	1081 NX

Basal glandular cells	3335 NX
Prostate	3335 NX

Basal keratinocytes	2794 NX
Skin	2794 NX

Bipolar cells	249 NX
Eye	249 NX

Cardiomyocytes	237 NX
Heart muscle	237 NX

Cholangiocytes	1470 NX
Liver	1470 NX

Ciliated cells	906 NX
Lung	906 NX

Club cells	1553 NX
Lung	1553 NX

Collecting duct cells	604 NX
Kidney	604 NX

Cone photoreceptor cells	130 NX
Eye	130 NX

Cytotrophoblasts	2560 NX
Placenta	2560 NX

Distal tubular cells	2968 NX
Kidney	2968 NX

Ductal cells	1798 NX
Pancreas	1798 NX

Early spermatids	320 NX
Testis	320 NX

Endothelial cells	2016 NX
Prostate	2416 NX
Testis	2257 NX
Placenta	2201 NX
Skin	2125 NX
Liver	2016 NX
Pancreas	1451 NX
Lung	1021 NX
Eye	547 NX
Heart muscle	152 NX

Enterocytes	774 NX
Small intestine	901 NX
Colon	741 NX
Rectum	583 NX

Erythroid cells	724 NX
Liver	724 NX

Exocrine glandular cells	2638 NX
Pancreas	2638 NX

Extravillous trophoblasts	3962 NX
Placenta	3962 NX

Fibroblasts	1779 NX
Lung	2839 NX
Placenta	2009 NX
Skin	1838 NX
Prostate	1647 NX
Heart muscle	208 NX

Glandular cells	2297 NX
Prostate	2297 NX

Granulocytes	1230 NX
Lung	1688 NX
Colon	771 NX

Hepatocytes	1338 NX
Liver	1338 NX

Hofbauer cells	1682 NX
Placenta	1682 NX

Horizontal cells	114 NX
Eye	114 NX

Intestinal endocrine cells	1335 NX
Rectum	1769 NX
Colon	901 NX

Ito cells	1476 NX
Liver	1476 NX

Kupffer cells	2186 NX
Liver	2186 NX

Late spermatids	569 NX
Testis	569 NX

Leydig cells	2639 NX
Testis	2639 NX

Macrophages	2338 NX
Testis	2989 NX
Prostate	2901 NX
Skin	2416 NX
Kidney	2377 NX
Lung	1613 NX
Pancreas	978 NX

Melanocytes	1802 NX
Skin	1802 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	2648 NX
Pancreas	2648 NX

Mucus-secreting cells	1649 NX
Rectum	3087 NX
Colon	1448 NX
Small intestine	1113 NX

Muller glia cells	361 NX
Eye	361 NX

Pancreatic endocrine cells	2447 NX
Pancreas	2447 NX

Paneth cells	1150 NX
Rectum	2688 NX
Small intestine	1150 NX
Colon	645 NX

Peritubular cells	1495 NX
Testis	1495 NX

Proximal tubular cells	2579 NX
Kidney	2579 NX

Rod photoreceptor cells	298 NX
Eye	298 NX

Sertoli cells	912 NX
Testis	912 NX

Smooth muscle cells	2154 NX
Skin	2488 NX
Prostate	2176 NX
Pancreas	2104 NX
Heart muscle	202 NX

Spermatocytes	404 NX
Testis	404 NX

Spermatogonia	478 NX
Testis	478 NX

Suprabasal keratinocytes	3191 NX
Skin	3191 NX

Syncytiotrophoblasts	2566 NX
Placenta	2566 NX

T-cells	2157 NX
Kidney	3318 NX
Skin	3108 NX
Liver	2241 NX
Prostate	2157 NX
Lung	1899 NX
Colon	1022 NX

Undifferentiated cells	2203 NX
Rectum	2923 NX
Small intestine	2203 NX
Colon	1253 NX

Urothelial cells	3048 NX
Prostate	3048 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.