Cell type atlas - RPS5 - The Human Protein Atlas

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RPS5

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RPS5
Gene descriptionⁱ Full gene name according to HGNC.	Ribosomal protein S5
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	6

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (HEK93)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	631 NX
Lung	631 NX

Alveolar cells type 2	924 NX
Lung	924 NX

B-cells	3949 NX
Kidney	4153 NX
Liver	4110 NX
Colon	1241 NX

Basal glandular cells	4137 NX
Prostate	4137 NX

Basal keratinocytes	5256 NX
Skin	5256 NX

Bipolar cells	230 NX
Eye	230 NX

Cardiomyocytes	214 NX
Heart muscle	214 NX

Cholangiocytes	1399 NX
Liver	1399 NX

Ciliated cells	744 NX
Lung	744 NX

Club cells	1369 NX
Lung	1369 NX

Collecting duct cells	499 NX
Kidney	499 NX

Cone photoreceptor cells	116 NX
Eye	116 NX

Cytotrophoblasts	2770 NX
Placenta	2770 NX

Distal tubular cells	1545 NX
Kidney	1545 NX

Ductal cells	1265 NX
Pancreas	1265 NX

Early spermatids	385 NX
Testis	385 NX

Endothelial cells	1387 NX
Skin	3138 NX
Prostate	3125 NX
Testis	1785 NX
Placenta	1657 NX
Liver	1387 NX
Pancreas	1117 NX
Eye	631 NX
Lung	621 NX
Heart muscle	191 NX

Enterocytes	1114 NX
Small intestine	1390 NX
Colon	1114 NX
Rectum	649 NX

Erythroid cells	958 NX
Liver	958 NX

Exocrine glandular cells	3964 NX
Pancreas	3964 NX

Extravillous trophoblasts	3620 NX
Placenta	3620 NX

Fibroblasts	2102 NX
Skin	2433 NX
Prostate	2067 NX
Placenta	2033 NX
Lung	1538 NX
Heart muscle	276 NX

Glandular cells	2996 NX
Prostate	2996 NX

Granulocytes	963 NX
Lung	1200 NX
Colon	725 NX

Hepatocytes	1143 NX
Liver	1143 NX

Hofbauer cells	1752 NX
Placenta	1752 NX

Horizontal cells	154 NX
Eye	154 NX

Intestinal endocrine cells	1189 NX
Rectum	1514 NX
Colon	863 NX

Ito cells	1113 NX
Liver	1113 NX

Kupffer cells	1555 NX
Liver	1555 NX

Late spermatids	982 NX
Testis	982 NX

Leydig cells	2000 NX
Testis	2000 NX

Macrophages	1866 NX
Prostate	2745 NX
Skin	2720 NX
Testis	1967 NX
Kidney	1766 NX
Lung	876 NX
Pancreas	751 NX

Melanocytes	2306 NX
Skin	2306 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	1599 NX
Pancreas	1599 NX

Mucus-secreting cells	2098 NX
Rectum	3103 NX
Colon	1835 NX
Small intestine	1641 NX

Muller glia cells	278 NX
Eye	278 NX

Pancreatic endocrine cells	2061 NX
Pancreas	2061 NX

Paneth cells	1315 NX
Rectum	2547 NX
Small intestine	1315 NX
Colon	1178 NX

Peritubular cells	889 NX
Testis	889 NX

Proximal tubular cells	1782 NX
Kidney	1782 NX

Rod photoreceptor cells	312 NX
Eye	312 NX

Sertoli cells	686 NX
Testis	686 NX

Smooth muscle cells	2562 NX
Skin	2882 NX
Prostate	2714 NX
Pancreas	1723 NX
Heart muscle	168 NX

Spermatocytes	411 NX
Testis	411 NX

Spermatogonia	549 NX
Testis	549 NX

Suprabasal keratinocytes	6343 NX
Skin	6343 NX

Syncytiotrophoblasts	2655 NX
Placenta	2655 NX

T-cells	2338 NX
Skin	2752 NX
Prostate	2628 NX
Kidney	2568 NX
Liver	2052 NX
Lung	1316 NX
Colon	956 NX

Undifferentiated cells	2937 NX
Rectum	3159 NX
Small intestine	3091 NX
Colon	1286 NX

Urothelial cells	3861 NX
Prostate	3861 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.