Cell type atlas - PAFAH1B3 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

PAFAH1B3

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	PAFAH1B3
Gene descriptionⁱ Full gene name according to HGNC.	Platelet activating factor acetylhydrolase 1b catalytic subunit 3
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Enzymes
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	7

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Spermatogonia)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Spermatogonia)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	15 NX
Lung	15 NX

Alveolar cells type 2	9 NX
Lung	9 NX

B-cells	22 NX
Liver	35 NX
Colon	27 NX
Kidney	18 NX

Basal glandular cells	37 NX
Prostate	37 NX

Basal keratinocytes	25 NX
Skin	25 NX

Bipolar cells	25 NX
Eye	25 NX

Cardiomyocytes	1 NX
Heart muscle	1 NX

Cholangiocytes	28 NX
Liver	28 NX

Ciliated cells	31 NX
Lung	31 NX

Club cells	16 NX
Lung	16 NX

Collecting duct cells	31 NX
Kidney	31 NX

Cone photoreceptor cells	14 NX
Eye	14 NX

Cytotrophoblasts	30 NX
Placenta	30 NX

Distal tubular cells	68 NX
Kidney	68 NX

Ductal cells	89 NX
Pancreas	89 NX

Early spermatids	13 NX
Testis	13 NX

Endothelial cells	17 NX
Placenta	41 NX
Testis	34 NX
Skin	30 NX
Pancreas	25 NX
Prostate	17 NX
Lung	15 NX
Eye	9 NX
Liver	9 NX
Heart muscle	6 NX

Enterocytes	21 NX
Small intestine	28 NX
Colon	21 NX
Rectum	19 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	48 NX
Pancreas	48 NX

Extravillous trophoblasts	34 NX
Placenta	34 NX

Fibroblasts	22 NX
Placenta	27 NX
Lung	22 NX
Skin	7 NX
Heart muscle	7 NX
Prostate	6 NX

Glandular cells	30 NX
Prostate	30 NX

Granulocytes	28 NX
Colon	37 NX
Lung	19 NX

Hepatocytes	7 NX
Liver	7 NX

Hofbauer cells	52 NX
Placenta	52 NX

Horizontal cells	11 NX
Eye	11 NX

Intestinal endocrine cells	57 NX
Rectum	73 NX
Colon	41 NX

Ito cells	9 NX
Liver	9 NX

Kupffer cells	23 NX
Liver	23 NX

Late spermatids	16 NX
Testis	16 NX

Leydig cells	13 NX
Testis	13 NX

Macrophages	23 NX
Kidney	37 NX
Prostate	35 NX
Skin	27 NX
Pancreas	23 NX
Testis	23 NX
Lung	10 NX

Melanocytes	44 NX
Skin	44 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	11 NX
Pancreas	11 NX

Mucus-secreting cells	47 NX
Colon	60 NX
Rectum	39 NX
Small intestine	31 NX

Muller glia cells	24 NX
Eye	24 NX

Pancreatic endocrine cells	79 NX
Pancreas	79 NX

Paneth cells	25 NX
Rectum	50 NX
Small intestine	25 NX
Colon	23 NX

Peritubular cells	9 NX
Testis	9 NX

Proximal tubular cells	40 NX
Kidney	40 NX

Rod photoreceptor cells	17 NX
Eye	17 NX

Sertoli cells	0 NX
Testis	0 NX

Smooth muscle cells	6 NX
Pancreas	39 NX
Prostate	8 NX
Skin	6 NX
Heart muscle	5 NX

Spermatocytes	4 NX
Testis	4 NX

Spermatogonia	212 NX
Testis	212 NX

Suprabasal keratinocytes	16 NX
Skin	16 NX

Syncytiotrophoblasts	11 NX
Placenta	11 NX

T-cells	18 NX
Skin	34 NX
Kidney	26 NX
Colon	25 NX
Prostate	18 NX
Lung	14 NX
Liver	13 NX

Undifferentiated cells	64 NX
Small intestine	66 NX
Colon	63 NX
Rectum	62 NX

Urothelial cells	43 NX
Prostate	43 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.