Cell type atlas - DNAJC10 - The Human Protein Atlas

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DNAJC10

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	DNAJC10
Gene descriptionⁱ Full gene name according to HGNC.	DnaJ heat shock protein family (Hsp40) member C10
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Membrane
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	5

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Early spermatids, Ciliated cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Early spermatids, Ciliated cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	42 NX
Lung	42 NX

Alveolar cells type 2	20 NX
Lung	20 NX

B-cells	55 NX
Kidney	62 NX
Liver	51 NX
Colon	49 NX

Basal glandular cells	15 NX
Prostate	15 NX

Basal keratinocytes	15 NX
Skin	15 NX

Bipolar cells	34 NX
Eye	34 NX

Cardiomyocytes	38 NX
Heart muscle	38 NX

Cholangiocytes	38 NX
Liver	38 NX

Ciliated cells	157 NX
Lung	157 NX

Club cells	46 NX
Lung	46 NX

Collecting duct cells	54 NX
Kidney	54 NX

Cone photoreceptor cells	18 NX
Eye	18 NX

Cytotrophoblasts	10 NX
Placenta	10 NX

Distal tubular cells	5 NX
Kidney	5 NX

Ductal cells	42 NX
Pancreas	42 NX

Early spermatids	165 NX
Testis	165 NX

Endothelial cells	37 NX
Lung	96 NX
Heart muscle	71 NX
Pancreas	65 NX
Placenta	43 NX
Eye	37 NX
Liver	36 NX
Testis	33 NX
Prostate	30 NX
Skin	28 NX

Enterocytes	8 NX
Rectum	10 NX
Colon	8 NX
Small intestine	7 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	54 NX
Pancreas	54 NX

Extravillous trophoblasts	35 NX
Placenta	35 NX

Fibroblasts	31 NX
Lung	76 NX
Heart muscle	61 NX
Skin	37 NX
Prostate	27 NX
Placenta	26 NX

Glandular cells	40 NX
Prostate	40 NX

Granulocytes	29 NX
Lung	49 NX
Colon	9 NX

Hepatocytes	22 NX
Liver	22 NX

Hofbauer cells	33 NX
Placenta	33 NX

Horizontal cells	22 NX
Eye	22 NX

Intestinal endocrine cells	31 NX
Rectum	35 NX
Colon	27 NX

Ito cells	39 NX
Liver	39 NX

Kupffer cells	30 NX
Liver	30 NX

Late spermatids	41 NX
Testis	41 NX

Leydig cells	34 NX
Testis	34 NX

Macrophages	30 NX
Lung	53 NX
Kidney	34 NX
Testis	33 NX
Prostate	27 NX
Pancreas	26 NX
Skin	22 NX

Melanocytes	19 NX
Skin	19 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	10 NX
Pancreas	10 NX

Mucus-secreting cells	111 NX
Colon	147 NX
Small intestine	93 NX
Rectum	88 NX

Muller glia cells	20 NX
Eye	20 NX

Pancreatic endocrine cells	38 NX
Pancreas	38 NX

Paneth cells	15 NX
Small intestine	28 NX
Rectum	15 NX
Colon	12 NX

Peritubular cells	42 NX
Testis	42 NX

Proximal tubular cells	19 NX
Kidney	19 NX

Rod photoreceptor cells	26 NX
Eye	26 NX

Sertoli cells	45 NX
Testis	45 NX

Smooth muscle cells	35 NX
Heart muscle	126 NX
Prostate	35 NX
Skin	35 NX
Pancreas	35 NX

Spermatocytes	87 NX
Testis	87 NX

Spermatogonia	41 NX
Testis	41 NX

Suprabasal keratinocytes	13 NX
Skin	13 NX

Syncytiotrophoblasts	9 NX
Placenta	9 NX

T-cells	21 NX
Lung	68 NX
Prostate	26 NX
Colon	23 NX
Skin	21 NX
Kidney	18 NX
Liver	16 NX

Undifferentiated cells	20 NX
Colon	22 NX
Small intestine	18 NX
Rectum	17 NX

Urothelial cells	17 NX
Prostate	17 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.