Cell type atlas - MRPS34 - The Human Protein Atlas

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MRPS34

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MRPS34
Gene descriptionⁱ Full gene name according to HGNC.	Mitochondrial ribosomal protein S34
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes Plasma proteins Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (HEK93)
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in many
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	36 NX
Lung	36 NX

Alveolar cells type 2	28 NX
Lung	28 NX

B-cells	77 NX
Liver	142 NX
Kidney	98 NX
Colon	43 NX

Basal glandular cells	57 NX
Prostate	57 NX

Basal keratinocytes	89 NX
Skin	89 NX

Bipolar cells	44 NX
Eye	44 NX

Cardiomyocytes	53 NX
Heart muscle	53 NX

Cholangiocytes	94 NX
Liver	94 NX

Ciliated cells	24 NX
Lung	24 NX

Club cells	40 NX
Lung	40 NX

Collecting duct cells	93 NX
Kidney	93 NX

Cone photoreceptor cells	10 NX
Eye	10 NX

Cytotrophoblasts	160 NX
Placenta	160 NX

Distal tubular cells	212 NX
Kidney	212 NX

Ductal cells	101 NX
Pancreas	101 NX

Early spermatids	5 NX
Testis	5 NX

Endothelial cells	54 NX
Placenta	104 NX
Liver	63 NX
Testis	61 NX
Skin	56 NX
Pancreas	54 NX
Heart muscle	52 NX
Eye	39 NX
Prostate	32 NX
Lung	15 NX

Enterocytes	190 NX
Colon	208 NX
Small intestine	196 NX
Rectum	107 NX

Erythroid cells	23 NX
Liver	23 NX

Exocrine glandular cells	158 NX
Pancreas	158 NX

Extravillous trophoblasts	146 NX
Placenta	146 NX

Fibroblasts	58 NX
Placenta	89 NX
Skin	57 NX
Heart muscle	52 NX
Prostate	33 NX
Lung	32 NX

Glandular cells	70 NX
Prostate	70 NX

Granulocytes	35 NX
Lung	42 NX
Colon	28 NX

Hepatocytes	146 NX
Liver	146 NX

Hofbauer cells	153 NX
Placenta	153 NX

Horizontal cells	52 NX
Eye	52 NX

Intestinal endocrine cells	88 NX
Colon	88 NX
Rectum	87 NX

Ito cells	64 NX
Liver	64 NX

Kupffer cells	98 NX
Liver	98 NX

Late spermatids	9 NX
Testis	9 NX

Leydig cells	67 NX
Testis	67 NX

Macrophages	59 NX
Kidney	122 NX
Pancreas	112 NX
Testis	76 NX
Prostate	57 NX
Skin	56 NX
Lung	30 NX

Melanocytes	78 NX
Skin	78 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	88 NX
Pancreas	88 NX

Mucus-secreting cells	128 NX
Colon	210 NX
Small intestine	134 NX
Rectum	112 NX

Muller glia cells	65 NX
Eye	65 NX

Pancreatic endocrine cells	127 NX
Pancreas	127 NX

Paneth cells	139 NX
Small intestine	154 NX
Rectum	139 NX
Colon	124 NX

Peritubular cells	66 NX
Testis	66 NX

Proximal tubular cells	175 NX
Kidney	175 NX

Rod photoreceptor cells	31 NX
Eye	30 NX

Sertoli cells	19 NX
Testis	19 NX

Smooth muscle cells	66 NX
Pancreas	153 NX
Heart muscle	66 NX
Skin	64 NX
Prostate	44 NX

Spermatocytes	20 NX
Testis	20 NX

Spermatogonia	42 NX
Testis	42 NX

Suprabasal keratinocytes	106 NX
Skin	106 NX

Syncytiotrophoblasts	57 NX
Placenta	57 NX

T-cells	77 NX
Kidney	117 NX
Skin	93 NX
Colon	78 NX
Liver	77 NX
Lung	46 NX
Prostate	18 NX

Undifferentiated cells	177 NX
Colon	275 NX
Small intestine	179 NX
Rectum	161 NX

Urothelial cells	60 NX
Prostate	60 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.