Cell type atlas - MRPS35 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MRPS35

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	MRPS35
Gene descriptionⁱ Full gene name according to HGNC.	Mitochondrial ribosomal protein S35
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Ribosomal proteins
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	3

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Distal tubular cells)
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in many
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Distal tubular cells)

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	69 NX
Lung	69 NX

Alveolar cells type 2	32 NX
Lung	32 NX

B-cells	38 NX
Kidney	62 NX
Liver	38 NX
Colon	27 NX

Basal glandular cells	33 NX
Prostate	33 NX

Basal keratinocytes	42 NX
Skin	42 NX

Bipolar cells	20 NX
Eye	20 NX

Cardiomyocytes	84 NX
Heart muscle	84 NX

Cholangiocytes	51 NX
Liver	51 NX

Ciliated cells	90 NX
Lung	90 NX

Club cells	46 NX
Lung	46 NX

Collecting duct cells	49 NX
Kidney	49 NX

Cone photoreceptor cells	4 NX
Eye	4 NX

Cytotrophoblasts	93 NX
Placenta	93 NX

Distal tubular cells	206 NX
Kidney	206 NX

Ductal cells	68 NX
Pancreas	68 NX

Early spermatids	10 NX
Testis	10 NX

Endothelial cells	23 NX
Lung	55 NX
Pancreas	43 NX
Placenta	35 NX
Skin	25 NX
Prostate	23 NX
Liver	22 NX
Heart muscle	21 NX
Testis	20 NX
Eye	17 NX

Enterocytes	55 NX
Colon	62 NX
Small intestine	52 NX
Rectum	42 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	52 NX
Pancreas	52 NX

Extravillous trophoblasts	95 NX
Placenta	95 NX

Fibroblasts	27 NX
Lung	75 NX
Placenta	54 NX
Skin	25 NX
Heart muscle	24 NX
Prostate	21 NX

Glandular cells	45 NX
Prostate	45 NX

Granulocytes	53 NX
Colon	55 NX
Lung	51 NX

Hepatocytes	53 NX
Liver	53 NX

Hofbauer cells	65 NX
Placenta	65 NX

Horizontal cells	18 NX
Eye	18 NX

Intestinal endocrine cells	58 NX
Colon	71 NX
Rectum	45 NX

Ito cells	17 NX
Liver	17 NX

Kupffer cells	31 NX
Liver	31 NX

Late spermatids	5 NX
Testis	5 NX

Leydig cells	24 NX
Testis	24 NX

Macrophages	49 NX
Lung	76 NX
Pancreas	66 NX
Kidney	52 NX
Testis	45 NX
Prostate	38 NX
Skin	23 NX

Melanocytes	41 NX
Skin	41 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	66 NX
Pancreas	66 NX

Mucus-secreting cells	65 NX
Colon	97 NX
Rectum	65 NX
Small intestine	48 NX

Muller glia cells	26 NX
Eye	26 NX

Pancreatic endocrine cells	51 NX
Pancreas	51 NX

Paneth cells	42 NX
Rectum	78 NX
Small intestine	42 NX
Colon	23 NX

Peritubular cells	23 NX
Testis	23 NX

Proximal tubular cells	153 NX
Kidney	153 NX

Rod photoreceptor cells	14 NX
Eye	14 NX

Sertoli cells	26 NX
Testis	26 NX

Smooth muscle cells	33 NX
Pancreas	65 NX
Heart muscle	46 NX
Prostate	33 NX
Skin	30 NX

Spermatocytes	24 NX
Testis	24 NX

Spermatogonia	25 NX
Testis	25 NX

Suprabasal keratinocytes	46 NX
Skin	46 NX

Syncytiotrophoblasts	52 NX
Placenta	52 NX

T-cells	30 NX
Lung	60 NX
Kidney	49 NX
Colon	31 NX
Skin	30 NX
Liver	28 NX
Prostate	4 NX

Undifferentiated cells	93 NX
Colon	134 NX
Small intestine	107 NX
Rectum	85 NX

Urothelial cells	38 NX
Prostate	38 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.