Cell type atlas - SNX1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

SNX1

SUMMARY

TISSUE

CELL TYPE

PATHOLOGY

BRAIN

BLOOD

CELL

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	SNX1
Gene descriptionⁱ Full gene name according to HGNC.	Sorting nexin 1
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	8

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood cell distributionⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity
Cell line distributionⁱ RNA distribution category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level

SINGLE CELL TYPESⁱ A summary of single cell RNA (NX) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.
Single cell types Group Expression Alphabetical RNA single cell type specificity: Low cell type specificity

SINGLE CELL TISSUESⁱ Single cell RNA in cell types from tissue are shown separately for each analyzed tissue. For easier navigation across tissues, use the grey browser on the left side of the window. Barchart shows pTPM levels in each cluster of single cells. To the left, a UMAP plot illustrates the RNA expression profile. The tissue name and plots are clickable and redirect to a more detailed interactive page. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. Please note that the same cell type may be found in several clusters.
Cluster Expression Alphabetical Colon
Cluster Expression Alphabetical Eye
Cluster Expression Alphabetical Heart muscle
Cluster Expression Alphabetical Kidney
Cluster Expression Alphabetical Liver
Cluster Expression Alphabetical Lung
Cluster Expression Alphabetical Pancreas
Cluster Expression Alphabetical Placenta
Cluster Expression Alphabetical Prostate
Cluster Expression Alphabetical Rectum
Cluster Expression Alphabetical Skin
Cluster Expression Alphabetical Small intestine
Cluster Expression Alphabetical Testis

BLOODⁱ

Single cell data

Cluster

Expression

Alphabetical

PBMC

Flow sorted data

Lineage

Expression

Alphabetical

CELL LINESⁱ RNA expression data (NX) of tissue culture cell lines.The analyzed cell lines are divided into 16 color-coded groups according to the organ they were obtained from. Detailed information about a specific cell line is revealed by hovering over the corresponding bar in the chart. The chart is clickable and redirects to more Cell Atlas data. Read more
Organ Expression Alphabetical

Alveolar cells type 1	107 NX
Lung	107 NX

Alveolar cells type 2	59 NX
Lung	59 NX

B-cells	23 NX
Liver	32 NX
Kidney	18 NX
Colon	15 NX

Basal glandular cells	32 NX
Prostate	32 NX

Basal keratinocytes	24 NX
Skin	24 NX

Bipolar cells	17 NX
Eye	17 NX

Cardiomyocytes	42 NX
Heart muscle	42 NX

Cholangiocytes	31 NX
Liver	31 NX

Ciliated cells	31 NX
Lung	31 NX

Club cells	58 NX
Lung	58 NX

Collecting duct cells	17 NX
Kidney	17 NX

Cone photoreceptor cells	22 NX
Eye	22 NX

Cytotrophoblasts	45 NX
Placenta	45 NX

Distal tubular cells	28 NX
Kidney	28 NX

Ductal cells	33 NX
Pancreas	33 NX

Early spermatids	2 NX
Testis	2 NX

Endothelial cells	31 NX
Heart muscle	48 NX
Placenta	45 NX
Lung	38 NX
Testis	34 NX
Prostate	31 NX
Skin	26 NX
Eye	25 NX
Liver	25 NX
Pancreas	18 NX

Enterocytes	29 NX
Small intestine	38 NX
Rectum	36 NX
Colon	24 NX

Erythroid cells	0 NX
Liver	0 NX

Exocrine glandular cells	32 NX
Pancreas	32 NX

Extravillous trophoblasts	30 NX
Placenta	30 NX

Fibroblasts	32 NX
Lung	48 NX
Placenta	38 NX
Heart muscle	37 NX
Skin	27 NX
Prostate	25 NX

Glandular cells	26 NX
Prostate	26 NX

Granulocytes	37 NX
Lung	56 NX
Colon	18 NX

Hepatocytes	29 NX
Liver	29 NX

Hofbauer cells	63 NX
Placenta	63 NX

Horizontal cells	14 NX
Eye	14 NX

Intestinal endocrine cells	26 NX
Rectum	37 NX
Colon	14 NX

Ito cells	31 NX
Liver	31 NX

Kupffer cells	43 NX
Liver	43 NX

Late spermatids	3 NX
Testis	3 NX

Leydig cells	30 NX
Testis	30 NX

Macrophages	40 NX
Pancreas	70 NX
Lung	57 NX
Testis	43 NX
Prostate	38 NX
Kidney	31 NX
Skin	27 NX

Melanocytes	30 NX
Skin	30 NX

Mixed cell types	NX
Pancreas	NX

Mixed immune cells	NX
Heart muscle	NX

Monocytes	42 NX
Pancreas	42 NX

Mucus-secreting cells	27 NX
Small intestine	37 NX
Rectum	29 NX
Colon	16 NX

Muller glia cells	18 NX
Eye	18 NX

Pancreatic endocrine cells	35 NX
Pancreas	35 NX

Paneth cells	27 NX
Small intestine	42 NX
Rectum	27 NX
Colon	14 NX

Peritubular cells	35 NX
Testis	35 NX

Proximal tubular cells	39 NX
Kidney	39 NX

Rod photoreceptor cells	15 NX
Eye	15 NX

Sertoli cells	45 NX
Testis	45 NX

Smooth muscle cells	32 NX
Heart muscle	64 NX
Skin	33 NX
Pancreas	27 NX
Prostate	26 NX

Spermatocytes	26 NX
Testis	26 NX

Spermatogonia	19 NX
Testis	19 NX

Suprabasal keratinocytes	24 NX
Skin	24 NX

Syncytiotrophoblasts	40 NX
Placenta	40 NX

T-cells	29 NX
Lung	46 NX
Liver	35 NX
Colon	31 NX
Prostate	26 NX
Kidney	26 NX
Skin	24 NX

Undifferentiated cells	27 NX
Small intestine	33 NX
Rectum	24 NX
Colon	21 NX

Urothelial cells	28 NX
Prostate	28 NX

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.