CTAGE5 protein expression summary - The Human Protein Atlas

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HUMAN PROTEIN ATLAS SUMMARYⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Proteinⁱ Full gene name according to HGNC.	CTAGE family member 5, ER export factor
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	CTAGE5 (cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, MEA6, MGEA, MGEA11, MGEA6)
Tissue specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5. The categories include: tissue enriched, group enriched, tissue enhanced, low tissue specificity and not detected. Read more	Low tissue specificity
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Ciliated cells)
Blood specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed blood cell samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low immune cell specificity
Brain specificityⁱ The regional specificity category is based on mRNA expression levels in the analyzed brain samples, grouped into 10 main brain regions and calculated for the three different species. The human brain expression profile is based on a combination of data from GTEX and FANTOM5. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low human brain regional specificity
Cancer prognostic summary	Prognostic marker in renal cancer (favorable)
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular, Membrane (different isoforms)
Subcellular summaryⁱ The main location is characterized by presence in all tested cell lines and/or increased intensity compared to other locations. Additional locations are characterized by either a markedly lower staining intensity than the main location, or that it is only observed in a subset of the cell lines.	Located in Endoplasmic reticulum
Protein function (UniProt)ⁱ Useful information about the protein provided by UniProt.	Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites. [O15320] Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum 1, 2, 3, 4. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum 5. Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity). Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites 6, 7, 8. [Q96PC5] ... show less
Gene summary (Entrez)ⁱ Useful information about the gene from Entrez	This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI). Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Sep 2016]... show less

TISSUE ATLASⁱ Summary of data presented in the Tissue Atlas and representative images of protein expression (left) and mRNA expression (right). The images are clickable and will redirect to more Tissue Atlas data. The Tissue Atlas contains information regarding the expression profiles of protein-coding genes in normal human tissue, both on the mRNA and protein level. The protein expression data is derived from antibody-based protein profiling using immunohistochemistry. Read more

Tissue specificity (RNA)ⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5. The categories include: tissue enriched, group enriched, tissue enhanced, low tissue specificity and not detected. Read more	Low tissue specificity
Tissue distribution (RNA)ⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Protein expressionⁱ A summary of the overall protein expression pattern across the analyzed normal tissues. The summary is based on knowledge-based annotation. "Estimation of protein expression could not be performed. View primary data." is shown for genes analyzed with a knowledge-based approach where available RNA-seq and gene/protein characterization data has been evaluated as not sufficient in combination with immunohistochemistry data to yield a reliable estimation of the protein expression profile. Read more	Cytoplasmic expression in most tissues, most abundant in glandular and neuronal cells.

SINGLE CELL TYPE ATLASⁱ Summary of data presented in the Cell Type Atlas and an interactive image showing mRNA expression in cell type groups e.g. epithelial cells and germ cells. The image is clickable and will redirect to more Cell Type Atlas data. The Cell Type Atlas contains information about single cell type RNA expression based on scRNAseq of human tissues. The data also covers transcriptomics analysis of human blood and cultured cell lines. Read more

Cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Cell type enhanced (Ciliated cells)
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Cell line enhanced (CAPAN-2)

PATHOLOGY ATLASⁱ Summary of data presented in the Pathology Atlas , with representative images of protein expression in cancer (left) and correlation between mRNA expression and patient survival (right). Images are clickable and redirect to pages with more Pathology Atlas data. The Pathology Atlas contains mRNA and protein expression data from 17 different forms of human cancer, as well as correlation analysis of mRNA expression and patient survival. The protein expression data is derived from antibody-based protein profiling using immunohistochemistry. Read more
	Renal cancer p<0.001
Prognostic summary	Prognostic marker in renal cancer (favorable)
Cancer specificity (RNA)ⁱ Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected. Read more	Low cancer specificity
Cancer distribution (RNA)ⁱ Distribution of RNA expression in 17 cancer types is categorized as either detected in single, detected in some, detected in many, detected in all, or not detected. Read more	Detected in many

Human regional specificityⁱ

Low region specificity

BLOOD ATLASⁱ Summary of data presented in the Blood Atlas and a representative image of mRNA expression in immune cells in the blood. The image is clickable and will redirect to more Blood Atlas data. The Blood Atlas contains single cell type RNA information covering various immune cells in the blood, e.g. B-cells and granulocytes. Analysis of the human secretome (including annotation of the genes predicted to be actively secreted to human blood) and proteins detected in human blood are also presented. Read more

Secretome annotationⁱ All genes with at least one predicted secreted isoform have been annotated and classified with the aim to determine if the corresponding protein(s) are: secreted into blood locally secreted or actually being attached to membrane or retained in intracellular locations like mitochondria, endoplasmatic reticulum (ER), Golgi apparatus or lysosomes. Read more	Intracellular and membrane
Immune cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Detected in blood by immunoassayⁱ The blood-based immunoassay category applies to actively secreted proteins and is based on plasma or serum protein concentrations established with enzyme-linked immunosorbent assays, compiled from a literature search. The categories include: detected and not detected, where detection refers to a concentration found in the literature search. Read more	No (not applicable)
Detected in blood by mass spectrometryⁱ Detection or not of the gene in blood, based on spectral count estimations from a publicly available mass spectrometry-based plasma proteomics data set obtained from the PeptideAtlas.	No

CELL ATLASⁱ Summary of data presented in the Cell Atlas and a representative image of subcellular localization. The Cell Atlas provides RNA expression data derived from RNA sequencing of a large panel of cell lines and protein localization data derived from antibody-based profiling by immunofluorescence confocal microscopy, using a subset of cell lines selected based on RNA expression. Read more

Main locationⁱ Main subcellular location(s) and reliability score(s) for the encoded protein(s) in human cells. The main location(s) may be characterized by presence in all tested cell lines and/or ihigher staining intensity compared to the potential additional location(s). If available, links to overrepresentation analyses in Reactome, a free, open-source, curated and peer reviewed biological pathway database, are provided. An analysis is done for the corresponding gene set of the proteome localizing to the main and additional locations of the protein on this page, respectively. Read more	Localized to the Endoplasmic reticulum
Cell cycle dependencyⁱ Cell-cycle dependance of single-cell varations in RNA and/or protein expression as observed in an additional assay for characterizing single-cell varations. "NA" indicates a lack of such data. Read more	NA

GENE INFORMATIONⁱ Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Gene name	CTAGE5 (HGNC Symbol)
Synonyms	cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, MEA6, MGEA, MGEA11, MGEA6
Description	CTAGE family member 5, ER export factor (HGNC Symbol)
Chromosome	14
Cytoband	q21.1
Chromosome location (bp)	39230231 - 39388513
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	15
Protein evidence	Evidence at protein level (all genes)
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Disease related genes Plasma proteins
Ensembl	ENSG00000150527 (version 92.38)
Entrez gene	4253
UniProt	O15320 (UniProt - Evidence at protein level), Q96PC5 (UniProt - Evidence at protein level)
neXtProt	NX_O15320, NX_Q96PC5
Antibodypedia	CTAGE5 antibodies

PROTEIN BROWSERⁱ

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PROTEIN INFORMATIONⁱ The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database. The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein. The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class. The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CTAGE5-201 ENSP00000280082 ENST00000280082		MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	654 aa 74.1 kDa	Yes	0
CTAGE5-202 ENSP00000280083 ENST00000280083	O15320 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Disease related genes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008047 [enzyme activator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0032527 [protein exit from endoplasmic reticulum] GO:0035459 [cargo loading into vesicle] GO:0043085 [positive regulation of catalytic activity] GO:0070971 [endoplasmic reticulum exit site] GO:0070973 [protein localization to endoplasmic reticulum exit site] Show all	804 aa 91 kDa	No	1
CTAGE5-203 ENSP00000339286 ENST00000341502	O15320 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Disease related genes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008047 [enzyme activator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0032527 [protein exit from endoplasmic reticulum] GO:0035459 [cargo loading into vesicle] GO:0043085 [positive regulation of catalytic activity] GO:0070971 [endoplasmic reticulum exit site] GO:0070973 [protein localization to endoplasmic reticulum exit site] Show all	771 aa 86.8 kDa	No	1
CTAGE5-204 ENSP00000343897 ENST00000341749	O15320 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Disease related genes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008047 [enzyme activator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0032527 [protein exit from endoplasmic reticulum] GO:0035459 [cargo loading into vesicle] GO:0043085 [positive regulation of catalytic activity] GO:0070971 [endoplasmic reticulum exit site] GO:0070973 [protein localization to endoplasmic reticulum exit site] Show all	792 aa 89.6 kDa	No	1
CTAGE5-205 ENSP00000343912 ENST00000348007	O15320 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Disease related genes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008047 [enzyme activator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0032527 [protein exit from endoplasmic reticulum] GO:0035459 [cargo loading into vesicle] GO:0043085 [positive regulation of catalytic activity] GO:0070971 [endoplasmic reticulum exit site] GO:0070973 [protein localization to endoplasmic reticulum exit site] Show all	761 aa 86.5 kDa	No	1
CTAGE5-206 ENSP00000379462 ENST00000396158	O15320 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Disease related genes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008047 [enzyme activator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0032527 [protein exit from endoplasmic reticulum] GO:0035459 [cargo loading into vesicle] GO:0043085 [positive regulation of catalytic activity] GO:0070971 [endoplasmic reticulum exit site] GO:0070973 [protein localization to endoplasmic reticulum exit site] Show all	809 aa 91.6 kDa	No	1
CTAGE5-207 ENSP00000379468 ENST00000396165	O15320 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Disease related genes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008047 [enzyme activator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0032527 [protein exit from endoplasmic reticulum] GO:0035459 [cargo loading into vesicle] GO:0043085 [positive regulation of catalytic activity] GO:0070971 [endoplasmic reticulum exit site] GO:0070973 [protein localization to endoplasmic reticulum exit site] Show all	775 aa 87.8 kDa	No	1
CTAGE5-208 ENSP00000450449 ENST00000553352	O15320 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Disease related genes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008047 [enzyme activator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0032527 [protein exit from endoplasmic reticulum] GO:0035459 [cargo loading into vesicle] GO:0043085 [positive regulation of catalytic activity] GO:0070971 [endoplasmic reticulum exit site] GO:0070973 [protein localization to endoplasmic reticulum exit site] Show all	775 aa 87.8 kDa	No	1
CTAGE5-210 ENSP00000452252 ENST00000553728	G3V599 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	1339 aa 151.7 kDa	Yes	1
CTAGE5-211 ENSP00000451164 ENST00000554392	G3V3C4 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	138 aa 15.7 kDa	No	1
CTAGE5-213 ENSP00000452395 ENST00000555716	G3V5K6 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] Show all	151 aa 17.4 kDa	No	1
CTAGE5-214 ENSP00000452562 ENST00000556148	O15320 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Disease related genes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008047 [enzyme activator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0032527 [protein exit from endoplasmic reticulum] GO:0035459 [cargo loading into vesicle] GO:0043085 [positive regulation of catalytic activity] GO:0070971 [endoplasmic reticulum exit site] GO:0070973 [protein localization to endoplasmic reticulum exit site] Show all	729 aa 82.4 kDa	No	0
CTAGE5-217 ENSP00000450869 ENST00000557038	O15320 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Disease related genes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006888 [ER to Golgi vesicle-mediated transport] GO:0008047 [enzyme activator activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0032527 [protein exit from endoplasmic reticulum] GO:0035459 [cargo loading into vesicle] GO:0043085 [positive regulation of catalytic activity] GO:0070971 [endoplasmic reticulum exit site] GO:0070973 [protein localization to endoplasmic reticulum exit site] Show all	724 aa 81.8 kDa	No	0
CTAGE5-218 ENSP00000451883 ENST00000557148	G3V4M1 [Direct mapping] Endoplasmic reticulum export factor CTAGE5 Show all	Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	92 aa 10.4 kDa	Yes	0
CTAGE5-219 ENSP00000491014 ENST00000640607	Q96PC5 [Target identity:100%; Query identity:100%] Melanoma inhibitory activity protein 2 A0A193H6U5 [Target identity:100%; Query identity:100%] TALI Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0070971 [endoplasmic reticulum exit site] Show all	1412 aa 159.8 kDa	Yes	1

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