AND
NOT
Field
All Gene name Protein class Uniprot keyword Chromosome External id Reliability score tissue (IHC) Reliability score mouse brain Reliability score cells (ICC) Protein array (PA) Western blot (WB) Immunohistochemistry (IHC) Immunocytochemistry (ICC) Secretome annotation Subcellular location (ICC) Subcellular location - cell line (ICC) Subcellular Cell Cycle Peak Phase Tissue expression (IHC) Tissue category (RNA) Cell type category (RNA) Cell line category (RNA) Cancer category (RNA) Brain region category (RNA) Blood cell category (RNA) Blood cell lineage category (RNA) Mouse brain category (RNA) Pig brain category (RNA) Prognostic cancer Metabolic pathway Evidence summary UniProt evidence NeXtProt evidence HPA evidence MS evidence With antibodies Has protein data Sort by
Class
Blood group antigen proteins Cancer-related genes Candidate cardiovascular disease genes CD markers Citric acid cycle related proteins Disease related genes Enzymes FDA approved drug targets G-protein coupled receptors Mapped to neXtProt Mapped to UniProt SWISS-PROT Nuclear receptors Plasma proteins Potential drug targets Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins Protein evidence (Peptideatlas) RAS pathway related proteins Ribosomal proteins RNA polymerase related proteins Transcription factors Transporters Voltage-gated ion channels
Subclass
Class
Biological process Molecular function Disease
Keyword
Chromosome
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 MT Unmapped X Y
Reliability
Enhanced Supported Approved Uncertain
Reliability
Supported Approved
Reliability
Enhanced Supported Approved Uncertain
Validation
Supported Approved Uncertain
Validation
Enhanced - Capture Enhanced - Genetic Enhanced - Independent Enhanced - Orthogonal Enhanced - Recombinant Supported Approved Uncertain
Validation
Enhanced - Independent Enhanced - Orthogonal Supported Approved Uncertain
Validation
Enhanced - Genetic Enhanced - Independent Enhanced - Recombinant Supported Approved Uncertain
Annotation
Intracellular and membrane Secreted - unknown location Secreted in brain Secreted in female reproductive system Secreted in male reproductive system Secreted in other tissues Secreted to blood Secreted to digestive system Secreted to extracellular matrix
Location
Actin filaments Aggresome Cell Junctions Centriolar satellite Centrosome Cleavage furrow Cytokinetic bridge Cytoplasmic bodies Cytosol Endoplasmic reticulum Endosomes Focal adhesion sites Golgi apparatus Intermediate filaments Kinetochore Lipid droplets Lysosomes Microtubule ends Microtubules Midbody Midbody ring Mitochondria Mitotic chromosome Mitotic spindle Nuclear bodies Nuclear membrane Nuclear speckles Nucleoli Nucleoli fibrillar center Nucleoli rim Nucleoplasm Peroxisomes Plasma membrane Rods & Rings Vesicles
Searches
Enhanced Supported Approved Uncertain Intensity variation Spatial variation Cell cycle intensity correlation Cell cycle spatial correlation Cell cycle biologically Custom data cell cycle dependant Cell cycle dependent protein Cell cycle independent protein Cell cycle dependent transcript Cell cycle independent transcript Multilocalizing Localizing 1 Localizing 2 Localizing 3 Localizing 4 Localizing 5 Localizing 6 Main location Additional location
Location
Any Actin filaments Aggresome Cell Junctions Centriolar satellite Centrosome Cleavage furrow Cytokinetic bridge Cytoplasmic bodies Cytosol Endoplasmic reticulum Endosomes Focal adhesion sites Golgi apparatus Intermediate filaments Kinetochore Lipid droplets Lysosomes Microtubule ends Microtubules Midbody Midbody ring Mitochondria Mitotic chromosome Mitotic spindle Nuclear bodies Nuclear membrane Nuclear speckles Nucleoli Nucleoli fibrillar center Nucleoli rim Nucleoplasm Peroxisomes Plasma membrane Rods & Rings Vesicles
Cell line
Any A-431 A549 AF22 ASC TERT1 BJ CACO-2 EFO-21 FHDF/TERT166 GAMG HaCaT HAP1 HBEC3-KT HBF TERT88 HDLM-2 HEK 293 HEL HeLa Hep G2 HTCEpi HTEC/SVTERT24-B HTERT-HME1 HTERT-RPE1 HUVEC TERT2 JURKAT K-562 LHCN-M2 MCF7 NB-4 OE19 PC-3 REH RH-30 RPTEC TERT1 RT4 SH-SY5Y SiHa SK-MEL-30 SuSa THP-1 U-2 OS U-251 MG
Type
Protein Rna
Phase
G1 S G2 M
Tissue
Any Adipose tissue Adrenal gland Appendix Bone marrow Breast Bronchus Cartilage Caudate Cerebellum Cerebral cortex Cervix, uterine Choroid plexus Colon Dorsal raphe Duodenum Endometrium Epididymis Esophagus Eye Fallopian tube Gallbladder Hair Heart muscle Hippocampus Hypothalamus Kidney Lactating breast Liver Lung Lymph node Nasopharynx Oral mucosa Ovary Pancreas Parathyroid gland Pituitary gland Placenta Prostate Rectum Retina Salivary gland Seminal vesicle Skeletal muscle Skin Small intestine Smooth muscle Soft tissue Sole of foot Spleen Stomach Substantia nigra Testis Thymus Thyroid gland Tonsil Urinary bladder Vagina
Cell type
Expression
Not detected Low Medium High
Tissue
Any Adipose tissue Adrenal gland Blood Bone marrow Brain Breast Cervix, uterine Ductus deferens Endometrium Epididymis Esophagus Fallopian tube Gallbladder Heart muscle Intestine Kidney Liver Lung Lymphoid tissue Ovary Pancreas Parathyroid gland Pituitary gland Placenta Prostate Retina Salivary gland Seminal vesicle Skeletal muscle Skin Smooth muscle Stomach Testis Thyroid gland Tongue Urinary bladder Vagina
Category
Tissue enriched Group enriched Tissue enhanced Low tissue specificity Not detected Detected in all Detected in many Detected in some Detected in single Is highest expressed
Cell type
Any Alveolar cells type 1 Alveolar cells type 2 B-cells Basal glandular cells Basal keratinocytes Bipolar cells Cardiomyocytes Cholangiocytes Ciliated cells Club cells Collecting duct cells Cone photoreceptor cells Cytotrophoblasts Distal tubular cells Ductal cells Early spermatids Endothelial cells Enterocytes Erythroid cells Exocrine glandular cells Extravillous trophoblasts Fibroblasts Glandular cells Granulocytes Hepatocytes Hofbauer cells Horizontal cells Intestinal endocrine cells Ito cells Kupffer cells Late spermatids Leydig cells Macrophages Melanocytes Monocytes Mucus-secreting cells Muller glia cells Pancreatic endocrine cells Paneth cells Peritubular cells Proximal tubular cells Rod photoreceptor cells Sertoli cells Smooth muscle cells Spermatocytes Spermatogonia Suprabasal keratinocytes Syncytiotrophoblasts T-cells Undifferentiated cells Urothelial cells
Category
Cell type enriched Group enriched Cell type enhanced Low cell type specificity Not detected Detected in all Detected in many Detected in some Detected in single Is highest expressed
Cell line
Any A-431 A549 AF22 AN3-CA ASC diff ASC TERT1 BEWO BJ BJ hTERT+ BJ hTERT+ SV40 Large T+ BJ hTERT+ SV40 Large T+ RasG12V CACO-2 CAPAN-2 Daudi EFO-21 FHDF/TERT166 GAMG HaCaT HAP1 HBEC3-KT HBF TERT88 HDLM-2 HEK 293 HEL HeLa Hep G2 HHSteC HL-60 HMC-1 HSkMC HTCEpi HTEC/SVTERT24-B HTERT-HME1 HTERT-RPE1 HUVEC TERT2 JURKAT K-562 Karpas-707 LHCN-M2 MCF7 MOLT-4 NB-4 NTERA-2 OE19 PC-3 REH RH-30 RPMI-8226 RPTEC TERT1 RT4 SCLC-21H SH-SY5Y SiHa SK-BR-3 SK-MEL-30 SuSa T-47d THP-1 TIME U-138 MG U-2 OS U-2197 U-251 MG U-266/70 U-266/84 U-698 U-87 MG U-937 WM-115
Category
Cell line enriched Group enriched Cell line enhanced Low cell line specificity Not detected Detected in all Detected in many Detected in some Detected in single Is highest expressed
Cancer
Any Breast cancer Cervical cancer Colorectal cancer Endometrial cancer Glioma Head and neck cancer Liver cancer Lung cancer Melanoma Ovarian cancer Pancreatic cancer Prostate cancer Renal cancer Stomach cancer Testis cancer Thyroid cancer Urothelial cancer
Category
Cancer enriched Group enriched Cancer enhanced Low cancer specificity Not detected Detected in all Detected in many Detected in some Detected in single Is highest expressed
Brain region
Any Amygdala Basal ganglia Cerebellum Cerebral cortex Hippocampal formation Hypothalamus Midbrain Olfactory region Pons and medulla Thalamus
Category
Region enriched Group enriched Region enhanced Low region specificity Not detected Detected in all Detected in many Detected in some Detected in single Is highest expressed
Cell type
Any Basophil Classical monocyte Eosinophil GdT-cell Intermediate monocyte MAIT T-cell Memory B-cell Memory CD4 T-cell Memory CD8 T-cell Myeloid DC Naive B-cell Naive CD4 T-cell Naive CD8 T-cell Neutrophil NK-cell Non-classical monocyte Plasmacytoid DC T-reg Total PBMC
Category
Cell type enriched Group enriched Cell type enhanced Low cell type specificity Not detected Detected in all Detected in many Detected in some Detected in single Is highest expressed
Cell lineage
Any B-cells Dendritic cells Granulocytes Monocytes NK-cells T-cells
Category
Lineage enriched Group enriched Lineage enhanced Low lineage specificity Not detected Detected in all Detected in many Detected in single Is highest expressed
Brain region
Any Amygdala Basal ganglia Cerebellum Cerebral cortex Corpus callosum Hippocampal formation Hypothalamus Midbrain Olfactory region Pituitary gland Pons and medulla Retina Thalamus
Category
Region enriched Group enriched Region enhanced Low region specificity Not detected Detected in all Detected in many Detected in some Detected in single Is highest expressed
Brain region
Any Amygdala Basal ganglia Cerebellum Cerebral cortex Corpus callosum Hippocampal formation Hypothalamus Midbrain Olfactory region Pituitary gland Pons and medulla Retina Spinal cord Thalamus
Category
Region enriched Group enriched Region enhanced Low region specificity Not detected Detected in all Detected in many Detected in some Detected in single Is highest expressed
Cancer
Breast cancer Cervical cancer Colorectal cancer Colorectal cancer Endometrial cancer Glioma Head and neck cancer Liver cancer Lung cancer Lung cancer Melanoma Ovarian cancer Pancreatic cancer Prostate cancer Renal cancer Renal cancer Renal cancer Stomach cancer Testis cancer Thyroid cancer Urothelial cancer
Prognosis
Favorable Unfavorable
Pathway
Acyl-CoA hydrolysis Acylglycerides metabolism Alanine; aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Aminoacyl-tRNA biosynthesis Androgen metabolism Arachidonic acid metabolism Arginine and proline metabolism Ascorbate and aldarate metabolism Beta oxidation of branched-chain fatty acids (mitochondrial) Beta oxidation of di-unsaturated fatty acids (n-6) (mitochondrial) Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal) Beta oxidation of even-chain fatty acids (mitochondrial) Beta oxidation of even-chain fatty acids (peroxisomal) Beta oxidation of odd-chain fatty acids (mitochondrial) Beta oxidation of phytanic acid (peroxisomal) Beta oxidation of poly-unsaturated fatty acids (mitochondrial) Beta oxidation of unsaturated fatty acids (n-7) (mitochondrial) Beta oxidation of unsaturated fatty acids (n-7) (peroxisomal) Beta oxidation of unsaturated fatty acids (n-9) (mitochondrial) Beta oxidation of unsaturated fatty acids (n-9) (peroxisomal) Beta-alanine metabolism Bile acid biosynthesis Bile acid recycling Biopterin metabolism Biotin metabolism Blood group biosynthesis Butanoate metabolism C5-branched dibasic acid metabolism Carnitine shuttle (cytosolic) Carnitine shuttle (endoplasmic reticular) Carnitine shuttle (mitochondrial) Carnitine shuttle (peroxisomal) Cholesterol biosynthesis 1 (Bloch pathway) Cholesterol biosynthesis 2 Cholesterol biosynthesis 3 (Kandustch-Russell pathway) Cholesterol metabolism Chondroitin / heparan sulfate biosynthesis Chondroitin sulfate degradation CoA synthesis Cysteine and methionine metabolism Drug metabolism Eicosanoid metabolism Estrogen metabolism Ether lipid metabolism Exchange/demand reactions Fatty acid activation (cytosolic) Fatty acid activation (endoplasmic reticular) Fatty acid biosynthesis Fatty acid biosynthesis (even-chain) Fatty acid biosynthesis (odd-chain) Fatty acid biosynthesis (unsaturated) Fatty acid desaturation (even-chain) Fatty acid desaturation (odd-chain) Fatty acid elongation (even-chain) Fatty acid elongation (odd-chain) Fatty acid oxidation Folate metabolism Formation and hydrolysis of cholesterol esters Fructose and mannose metabolism Galactose metabolism Glucocorticoid biosynthesis Glutathione metabolism Glycerolipid metabolism Glycerophospholipid metabolism Glycine; serine and threonine metabolism Glycolysis / Gluconeogenesis Glycosphingolipid biosynthesis-ganglio series Glycosphingolipid biosynthesis-globo series Glycosphingolipid biosynthesis-lacto and neolacto series Glycosphingolipid metabolism Glycosylphosphatidylinositol (GPI)-anchor biosynthesis Heme degradation Heme synthesis Heparan sulfate degradation Histidine metabolism Inositol phosphate metabolism Isolated Keratan sulfate biosynthesis Keratan sulfate degradation Leukotriene metabolism Linoleate metabolism Lipoic acid metabolism Lysine metabolism Metabolism of other amino acids Metabolism of xenobiotics by cytochrome P450 Miscellaneous N-glycan metabolism Nicotinate and nicotinamide metabolism Nitrogen metabolism Nucleotide metabolism O-glycan metabolism Omega-3 fatty acid metabolism Omega-6 fatty acid metabolism Oxidative phosphorylation Pantothenate and CoA biosynthesis Pentose and glucuronate interconversions Pentose phosphate pathway Phenylalanine metabolism Phenylalanine; tyrosine and tryptophan biosynthesis Phosphatidylinositol phosphate metabolism Pool reactions Porphyrin metabolism Propanoate metabolism Prostaglandin biosynthesis Protein assembly Protein degradation Protein modification Purine metabolism Pyrimidine metabolism Pyruvate metabolism Retinol metabolism Riboflavin metabolism ROS detoxification Serotonin and melatonin biosynthesis Sphingolipid metabolism Starch and sucrose metabolism Steroid metabolism Sulfur metabolism Terpenoid backbone biosynthesis Thiamine metabolism Transport reactions Triacylglycerol synthesis Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolism Tryptophan metabolism Tyrosine metabolism Ubiquinone synthesis Urea cycle Valine; leucine; and isoleucine metabolism Vitamin A metabolism Vitamin B12 metabolism Vitamin B2 metabolism Vitamin B6 metabolism Vitamin C metabolism Vitamin D metabolism Vitamin E metabolism Xenobiotics metabolism
Category
Evidence at protein level Evidence at transcript level No human protein/transcript evidence
Score
Evidence at protein level Evidence at transcript level No human protein/transcript evidence
Score
Evidence at protein level Evidence at transcript level No human protein/transcript evidence
Score
Evidence at protein level Evidence at transcript level No human protein/transcript evidence
Score
Evidence at protein level Evidence at transcript level No human protein/transcript evidence
In atlas
Tissue Cell Pathology Brain Blood - conc. immunoassay Blood - conc. mass spectrometry Blood - detected pea
Column
Gene Position Tissue specific score Prognostic Reliability (IF) Reliability (IH)