Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389806-36453791 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.4;lymphoid tissue: 32.7" "Cell type enhanced" "Detected in many" 21 "Early spermatids: 106.8;Late spermatids: 41.2;Spermatocytes: 20.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HBF TERT88: 100.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.7 0.6 13.9 7.2 10.5 20.9 1.3 1.8 36.7 1.9 3.9 1.6 0.0 2.9 1.3 2.4 12.8 0.6 1.4 0.6 24.0 12.1 0.7 0.8 3.3 4.2 30.5 2.5 0.9 0.4 0.3 0.3 12.9 9.7 0.7 5.5 0.0 0.9 0.3 0.4 8.9 3.4 9.4 63.4 1.6 3.3 9.2 12.5 32.7 0.6 17.7 6.7 2.6 1.3 0.0 0.3 0.6 0.9 0.0 1.7 2.0 68.4 14.4 12.0 9.1 1.6 4.2 12.9 43.2 25.3 52.2 39.2 9.8 21.2 3.4 12.5 21.8 27.8 35.3 9.4 25.2 100.3 2.3 6.8 4.7 16.2 8.1 0.2 6.7 5.5 0.9 1.1 34.0 22.4 6.2 16.2 4.6 9.8 7.3 42.5 10.3 5.7 7.8 13.3 10.5 15.2 4.2 36.0 2.3 11.5 11.2 5.1 6.0 22.7 26.4 3.9 17.4 17.8 7.7 15.3 32.7 36.8 19.2 50.4 3.0 4.8 6.4 11.1 10.9 68.6 0.0 0.9 0.1 0.0 0.2 0.0 0.0 0.9 0.5 0.3 0.0 0.6 0.0 0.6 0.0 0.3 0.2 1.7 2.0 13.9 10.5 1.8 7.7 24.0 12.1 30.5 2.5 9.7 12.5 0.0 0.6 0.0 1.0 12.6 0.0 0.6 0.0 2.7 1.2 0.0 0.0 2.5 0.0 0.5 106.8 0.1 0.9 0.0 0.2 20.2 3.5 1.3 0.0 0.0 8.0 0.0 0.0 1.8 1.5 41.2 1.1 2.6 0.0 0.0 2.2 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.4 20.9 14.9 8.2 2.4 1.5 1.6 1.4 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family, AAA domain containing 2" Q6PL18 8 123319850-123416350 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.8" "Cell type enhanced" "Detected in many" 7 "Spermatocytes: 74.6;Spermatogonia: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 75.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 4.1 4.9 4.6 12.6 9.2 22.8 7.2 5.6 6.9 14.0 8.6 1.5 13.4 5.3 4.7 5.0 10.7 4.7 3.5 13.7 4.2 6.3 2.2 10.1 9.8 13.7 4.0 4.3 9.9 3.9 3.5 18.7 5.2 4.0 11.4 7.5 2.4 6.8 15.4 13.8 7.2 6.6 5.5 4.1 8.8 6.9 20.2 3.4 53.8 4.8 6.3 12.7 9.9 5.9 4.3 2.3 7.2 2.8 4.0 7.4 1.8 25.5 9.9 14.2 4.8 2.5 3.2 6.2 20.0 6.9 17.3 19.3 7.5 11.1 16.7 6.1 6.3 6.8 12.2 18.9 6.4 27.8 23.2 10.1 30.0 10.7 15.2 1.0 10.9 14.9 1.0 1.0 16.4 5.4 3.7 5.2 9.8 14.0 17.0 12.8 26.4 31.4 8.2 2.5 19.3 9.9 16.4 16.9 9.0 6.1 11.7 18.2 7.9 29.0 75.6 5.1 6.0 15.4 10.4 3.2 13.1 18.1 10.3 24.0 5.5 9.8 15.5 8.6 18.4 10.2 7.2 1.5 5.4 2.9 1.3 4.0 4.3 4.2 4.8 2.3 2.8 2.8 3.0 0.4 4.0 2.8 0.3 7.4 1.8 4.6 9.2 5.6 6.9 4.2 6.3 4.0 4.3 4.0 3.4 6.0 8.3 14.2 19.9 14.1 2.5 22.9 2.5 5.3 11.4 3.5 3.9 8.2 1.7 2.4 46.2 6.7 2.2 23.3 1.9 21.2 7.3 19.9 13.9 14.0 9.7 1.6 1.2 9.2 11.1 17.9 6.9 6.6 1.7 5.4 4.4 5.2 2.7 3.5 13.1 0.9 2.1 0.0 8.6 74.6 90.7 10.7 11.3 15.3 12.8 24.8 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 32.3;testis: 41.1" "Cell type enhanced" "Detected in many" 8 "Erythroid cells: 70.0;Extravillous trophoblasts: 59.5;granulocytes: 55.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved Nucleoplasm,Centrosome,Cytosol Yes Yes "Nucleoplasm, Centrosome, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 3.7 2.3 1.5 12.7 1.3 8.3 3.0 1.3 1.8 1.4 6.7 1.3 0.8 7.3 1.8 1.2 7.7 1.1 3.7 4.1 1.1 1.1 2.4 5.1 2.9 12.3 1.6 0.9 8.3 1.4 0.3 0.7 6.1 1.5 1.0 8.3 1.5 2.7 0.5 6.9 2.1 7.2 2.7 1.3 7.4 4.3 41.1 1.1 32.3 1.2 5.9 13.3 2.4 2.4 3.9 5.2 6.0 8.7 2.0 6.6 2.6 33.0 24.4 16.3 11.5 0.9 2.1 20.7 27.1 12.7 65.7 27.7 68.2 23.2 10.8 18.7 11.1 34.1 26.7 29.0 18.2 70.0 9.8 11.1 19.3 25.0 42.5 0.5 25.8 27.2 1.0 1.9 22.7 20.4 5.2 15.3 17.7 21.9 8.6 27.9 33.7 15.4 20.0 14.9 27.1 25.1 11.7 31.5 12.0 10.5 8.7 14.1 7.6 37.9 43.6 18.2 15.6 25.8 16.1 8.8 28.6 28.3 15.8 38.2 12.1 14.0 18.8 15.4 15.0 23.6 0.2 5.3 6.0 1.9 8.7 2.9 3.9 3.3 1.9 5.2 1.4 1.5 1.5 3.7 2.0 4.8 1.2 6.6 2.6 1.5 1.3 1.3 1.8 1.1 1.1 1.6 0.9 1.5 1.1 0.0 3.2 4.5 1.1 1.0 1.0 3.4 2.5 1.4 2.3 3.5 2.0 9.8 1.7 3.9 16.9 1.6 5.3 70.0 4.2 59.5 3.8 0.7 55.2 2.4 14.8 1.6 5.8 3.1 2.4 9.5 1.4 5.5 0.0 18.0 5.7 3.5 3.6 3.5 0.4 1.9 2.5 6.5 2.1 16.2 31.6 1.0 6.9 4.9 9.8 1.4 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;lymphoid tissue: 59.9" "Group enriched" "Detected in many" 6 "Erythroid cells: 46.7;Extravillous trophoblasts: 76.2;Hofbauer cells: 23.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.9" "Lineage enriched" "Detected in many" 5 "T-cells: 10.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.2 1.3 0.4 22.1 0.6 19.7 2.0 0.6 0.6 2.6 5.8 0.5 0.9 5.9 0.9 1.3 17.1 0.3 2.2 1.0 0.4 0.2 1.4 1.8 2.4 17.8 0.4 0.4 0.8 0.6 0.0 0.4 3.8 0.8 0.9 5.5 0.7 2.7 0.4 2.1 5.0 8.1 1.3 0.7 11.2 4.2 1.2 0.4 59.9 0.5 8.0 19.1 2.1 5.0 2.3 0.8 1.2 0.6 0.5 10.9 1.4 41.6 28.6 42.7 20.5 0.9 1.4 16.4 20.0 10.8 41.5 38.3 37.0 12.6 41.6 10.4 7.9 17.3 30.7 30.9 13.7 34.3 18.2 50.8 24.8 16.4 31.2 0.1 13.0 24.4 0.7 0.6 24.3 15.2 4.1 19.0 27.4 15.4 16.1 18.1 19.8 47.5 18.6 26.5 13.7 12.7 32.2 39.3 17.2 9.0 8.2 9.3 13.2 17.8 8.0 13.6 13.3 14.0 8.8 7.4 16.6 17.1 14.9 52.0 11.8 7.8 31.3 8.0 19.9 33.6 0.0 0.6 0.9 0.6 0.4 0.2 1.6 1.9 3.1 0.8 2.3 0.2 1.0 1.2 0.5 0.3 0.2 10.9 1.4 0.4 0.6 0.6 0.6 0.4 0.2 0.4 0.4 0.8 0.4 0.0 0.3 2.2 0.3 3.9 0.0 1.1 0.0 0.0 3.4 0.0 0.0 5.1 0.0 0.2 0.0 0.0 1.4 46.7 0.0 76.2 4.7 0.4 4.6 0.6 23.9 0.0 0.0 4.9 6.3 0.0 0.6 4.4 1.7 0.0 4.2 0.0 0.2 2.9 0.0 0.0 0.0 0.0 0.3 0.7 2.0 2.0 7.6 2.5 6.3 1.4 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.6;testis: 51.4" "Cell type enhanced" "Detected in many" 9 "Early spermatids: 73.9;Erythroid cells: 116.8;Extravillous trophoblasts: 134.7;Spermatocytes: 133.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 14.0" "Lineage enriched" "Detected in many" 6 "T-cells: 14.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 2.3 1.5 0.4 14.1 0.7 20.8 5.3 0.7 0.6 1.9 4.8 0.3 0.2 4.6 0.9 1.4 13.4 0.4 2.2 2.4 0.5 0.4 1.3 2.2 2.4 9.7 0.6 0.2 0.9 0.8 0.0 0.4 6.1 0.5 0.9 5.2 0.2 2.1 0.2 0.6 3.5 4.7 2.4 0.7 6.3 3.2 51.4 0.3 61.6 0.5 14.4 11.7 2.0 3.2 2.5 0.8 0.5 0.0 2.2 14.0 3.0 32.0 30.0 27.1 29.3 1.7 2.8 10.0 24.7 13.9 35.3 23.2 24.5 12.7 33.1 10.1 14.3 26.7 17.1 27.4 15.8 30.9 11.1 38.0 21.8 17.7 28.8 0.2 20.9 16.4 0.9 1.1 19.5 14.5 5.1 24.9 25.0 27.3 28.0 27.1 18.6 44.6 20.0 20.1 22.7 52.8 23.3 44.0 25.5 8.3 11.9 33.5 23.1 18.9 21.5 16.8 13.8 28.4 19.9 9.3 42.7 37.9 18.4 35.1 20.3 16.3 38.2 15.6 8.8 37.1 0.0 0.0 0.0 0.7 0.0 0.2 2.5 4.3 2.8 0.8 0.3 0.0 0.4 0.5 2.2 0.0 0.3 14.0 3.0 0.4 0.7 0.7 0.6 0.5 0.4 0.6 0.2 0.5 0.3 0.0 30.7 18.5 1.0 7.2 0.5 2.0 5.1 4.0 17.0 0.0 0.0 17.0 0.0 1.2 73.9 0.6 1.8 116.8 0.0 134.7 7.2 0.9 9.2 1.6 43.1 0.0 2.9 11.1 11.1 29.8 2.8 11.5 1.7 0.0 3.4 0.4 0.4 3.4 0.7 0.0 0.5 6.5 1.0 133.1 40.7 5.6 16.0 7.5 15.2 4.0 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221136 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.5;testis: 25.6" "Group enriched" "Detected in many" 7 "Spermatocytes: 66.9;Spermatogonia: 28.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.8;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA008419 Supported Cytosol Yes Yes Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 1.0 0.9 0.3 18.4 0.6 11.4 1.5 0.4 0.5 1.3 4.0 0.4 0.1 3.3 1.1 0.8 6.5 0.5 1.1 0.6 0.4 0.4 0.8 0.7 1.8 8.7 0.4 0.3 0.6 0.5 0.0 0.4 3.4 0.5 0.6 4.4 0.3 1.6 0.1 0.7 2.3 2.9 1.2 0.6 5.4 1.7 25.6 0.1 49.5 0.5 3.1 10.6 1.1 2.0 2.8 2.8 0.0 0.2 0.7 0.7 0.5 21.8 11.1 35.5 14.1 0.9 2.5 11.5 20.8 11.7 22.3 19.4 16.2 8.4 19.8 11.7 7.5 20.5 24.7 33.5 11.3 24.3 17.0 18.0 28.9 28.7 15.0 0.0 26.1 15.9 0.5 0.6 13.6 12.8 4.4 16.1 22.9 24.9 21.1 22.2 7.4 20.4 15.9 24.0 18.4 12.7 21.9 29.2 15.0 6.8 11.1 23.2 14.3 12.8 12.3 4.5 16.2 14.3 13.5 9.3 17.1 18.1 17.0 18.4 11.1 18.8 32.4 9.1 29.3 22.2 0.0 0.0 0.0 0.2 0.2 0.3 2.4 0.7 0.6 0.7 2.8 0.1 0.4 0.0 0.7 0.1 2.8 0.0 0.5 0.3 0.6 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.1 3.0 1.4 0.8 0.3 0.7 0.4 0.4 0.0 0.0 3.4 0.0 0.0 1.3 0.0 0.3 2.5 0.0 0.3 0.0 0.0 5.1 0.4 0.2 0.0 0.2 4.3 0.0 0.0 1.3 0.6 2.4 1.4 1.5 0.0 0.0 1.4 0.0 0.8 0.8 0.4 0.0 0.1 6.5 0.0 66.9 28.8 0.3 0.7 0.8 1.7 0.4 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823933 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 122.3" "Cell type enhanced" "Detected in many" 13 "Erythroid cells: 70.0;Extravillous trophoblasts: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "T-reg: 6.8" "Group enriched" "Detected in many" 5 "NK-cells: 1.7;T-cells: 6.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 3.2 1.5 1.3 18.6 1.7 21.6 1.8 5.1 1.2 2.5 6.3 1.0 0.8 6.6 2.2 2.1 11.7 1.7 2.4 3.2 1.8 1.8 1.7 1.6 3.4 15.6 1.6 0.8 4.5 0.9 0.5 3.2 12.0 1.3 2.2 7.8 1.0 2.1 0.8 1.1 4.2 7.4 2.4 1.8 8.9 2.9 8.4 0.8 122.3 1.4 18.8 18.4 2.5 5.1 0.3 0.9 0.6 0.3 1.7 6.8 1.9 38.7 10.1 27.7 11.8 1.5 3.8 22.7 27.1 11.9 36.0 26.8 22.0 24.1 35.7 7.3 14.2 12.7 13.1 34.8 15.9 29.7 17.1 16.1 28.6 13.4 21.3 0.3 43.1 20.3 1.0 1.2 14.9 8.9 5.7 21.5 19.0 40.7 35.9 28.5 13.9 54.9 25.0 21.8 24.3 11.3 25.2 53.7 17.4 10.2 7.7 11.8 12.5 14.2 17.4 7.5 21.7 14.5 18.3 12.7 16.9 25.7 17.8 25.8 22.8 24.1 40.9 9.7 43.9 18.7 0.0 0.3 0.6 0.2 0.1 0.1 0.3 2.0 1.4 0.9 0.1 0.0 0.5 0.3 1.7 0.3 0.1 6.8 1.9 1.3 1.7 5.1 1.2 1.8 1.8 1.6 0.8 1.3 0.8 0.0 0.6 0.0 0.7 2.5 1.1 0.7 0.0 2.7 1.2 0.0 11.8 5.7 0.0 0.3 4.8 0.7 1.5 70.0 0.2 72.3 3.3 1.1 0.0 1.5 21.0 0.0 1.2 2.5 7.5 1.5 0.9 2.9 1.7 0.0 3.1 1.3 0.4 1.5 1.1 0.0 14.2 0.0 0.9 6.1 7.9 1.1 7.1 3.2 6.4 1.3 CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167010-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 71.4" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 610.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" 3.2 4.6 2.7 23.9 4.8 20.5 4.6 6.5 5.6 4.4 9.9 1.6 1.6 9.3 3.5 2.8 28.8 3.3 3.5 1.9 3.5 4.2 4.6 2.9 3.4 23.6 4.0 4.2 3.7 4.0 1.6 2.6 12.1 11.5 2.6 14.2 1.7 5.3 1.7 2.0 6.4 8.7 6.4 2.5 9.1 7.1 21.7 1.3 71.4 6.3 23.3 30.1 5.3 7.5 13.2 5.1 2.4 4.1 6.5 14.7 5.5 58.6 40.6 55.8 49.6 2.9 5.0 131.7 26.0 19.5 68.6 58.1 60.0 55.4 36.1 31.7 23.9 78.7 37.0 56.1 56.8 77.0 35.4 27.7 22.9 33.9 41.4 0.9 19.9 26.2 2.2 3.6 39.3 27.4 6.3 36.6 35.4 27.6 28.7 55.8 55.9 27.2 23.7 31.0 19.5 25.8 28.7 40.2 37.0 25.1 21.7 28.4 17.9 44.7 21.1 19.2 32.8 40.3 20.9 15.3 15.3 49.7 27.6 64.9 14.4 26.6 50.4 21.2 34.9 47.0 2.4 1.8 1.2 2.8 4.1 4.0 13.2 7.6 6.7 5.1 8.6 2.5 2.4 1.0 6.5 1.9 4.2 14.7 5.5 2.7 4.8 6.5 5.6 3.5 4.2 4.0 4.2 11.5 1.3 0.0 0.3 5.2 4.8 10.2 4.2 1.5 2.5 13.4 4.5 5.2 2.0 53.5 1.7 5.3 63.8 1.8 2.9 46.7 1.2 610.8 11.3 3.6 2.3 3.0 50.4 0.0 1.2 6.2 6.0 9.4 2.8 4.4 3.3 3.6 4.6 2.8 2.5 0.0 2.5 4.3 2.9 6.5 3.1 28.8 70.2 6.4 34.7 4.4 11.5 2.7 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105078-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 70.2;testis: 73.9" "Cell type enhanced" "Detected in many" 12 "Early spermatids: 102.4;Erythroid cells: 163.5;Extravillous trophoblasts: 106.5;Spermatocytes: 88.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in many" 4 "T-reg: 17.8" "Lineage enriched" "Detected in many" 6 "T-cells: 17.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 2.0 1.1 0.4 21.0 0.4 24.7 2.5 0.3 0.6 1.8 5.5 0.5 0.2 5.2 1.0 1.5 11.3 0.5 1.6 1.2 0.4 0.4 1.0 1.0 1.9 12.0 0.4 0.3 0.8 0.7 0.0 0.4 6.7 0.4 1.1 6.3 0.4 2.1 0.6 0.4 3.6 5.1 2.0 1.3 5.2 3.0 73.9 0.2 70.2 0.8 10.3 16.0 1.8 3.4 1.8 2.3 0.7 0.1 3.0 17.8 1.8 28.7 25.3 41.6 10.3 1.9 3.8 22.1 23.8 15.3 36.9 30.4 40.9 17.7 26.7 17.3 15.4 21.6 35.5 39.3 20.2 34.9 27.7 21.1 34.6 29.6 23.2 0.5 25.7 22.3 1.4 2.7 15.9 20.3 7.2 25.0 33.0 34.9 42.9 27.8 20.9 29.3 37.5 30.7 12.4 15.0 34.3 58.9 27.1 11.6 20.3 25.9 17.5 32.6 17.7 21.5 34.0 30.7 25.7 13.0 18.4 31.2 20.2 45.3 19.1 28.7 47.5 12.0 58.9 25.9 0.0 0.1 0.6 0.1 0.0 0.2 1.8 3.9 4.1 2.3 0.9 0.0 0.1 0.7 3.0 0.0 0.1 17.8 1.8 0.4 0.4 0.3 0.6 0.4 0.4 0.4 0.3 0.4 0.2 0.0 1.1 7.8 1.0 4.2 0.0 0.3 0.0 1.4 2.3 0.0 0.0 26.7 0.0 0.4 102.4 0.4 1.7 163.5 0.2 106.5 1.1 1.7 0.0 0.8 25.3 0.0 2.9 3.1 10.7 30.4 4.0 4.2 0.0 3.6 5.5 0.0 0.5 1.7 1.8 0.0 0.2 0.0 0.0 88.2 36.6 5.4 13.6 3.2 12.4 2.0 CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4273772-4305350 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cardiomyocytes: 305.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 32.3;HBEC3-KT: 29.5;HDLM-2: 49.7;Karpas-707: 71.8;RH-30: 47.0;SuSa: 37.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" 13.7 39.3 20.8 12.0 15.9 23.6 10.4 6.1 22.3 14.4 28.3 8.1 24.3 18.5 21.9 41.9 12.2 16.5 9.1 36.9 17.5 7.3 6.0 5.7 12.8 24.5 7.9 17.0 11.6 18.4 8.3 19.2 23.5 9.3 16.4 24.2 14.1 8.3 22.4 2.0 9.2 19.6 45.5 14.0 16.5 11.1 5.2 8.6 6.2 18.5 6.9 13.6 22.3 16.3 3.9 2.1 4.6 1.0 9.1 14.8 5.4 0.0 0.0 32.3 0.0 5.6 0.8 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.2 0.0 0.0 4.1 0.9 29.5 0.0 49.7 0.8 0.3 0.0 0.2 0.1 12.6 2.7 10.8 4.9 0.0 22.3 0.2 0.0 0.9 3.4 71.8 6.3 0.0 0.0 16.6 13.3 0.2 0.0 0.0 47.0 23.4 0.0 2.8 0.0 0.0 0.0 0.0 0.0 37.8 0.0 0.1 2.3 0.0 9.4 0.0 0.0 1.2 12.2 0.0 0.1 9.1 0.0 4.1 1.0 4.6 9.1 0.2 13.7 3.9 13.0 11.0 2.1 1.5 8.2 9.8 1.5 9.1 0.1 1.0 14.8 5.4 20.8 15.9 6.1 22.3 17.5 7.3 7.9 17.0 9.3 8.6 56.6 49.3 25.1 24.4 94.8 6.8 305.9 0.0 9.4 43.3 12.2 0.0 2.6 0.0 2.5 0.7 38.4 26.9 46.7 59.7 1.7 135.6 5.7 54.3 0.8 12.0 3.2 62.3 17.8 13.3 0.9 48.6 38.9 37.1 6.4 146.6 155.3 32.6 35.1 116.7 1.0 3.7 25.8 50.5 0.7 3.6 34.6 5.3 61.2 109.0 7.0 CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811898-29824308 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.3;placenta: 46.7" "Cell type enriched" "Detected in many" 14 "Extravillous trophoblasts: 1526.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 81.6" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm Yes Yes Nucleoplasm "CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (6.35e-6)" "unprognostic (5.78e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (3.89e-5)" "unprognostic (1.26e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.29e-2)" "unprognostic (7.07e-2)" "unprognostic (1.11e-16)" "unprognostic (5.61e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-2)" "unprognostic (1.46e-1)" 1.6 6.8 2.4 4.5 2.9 23.3 0.6 6.3 3.3 0.8 3.0 1.7 1.1 2.3 1.2 0.6 4.7 0.7 2.2 4.4 2.3 2.8 1.2 0.7 1.1 4.6 1.9 1.9 0.9 1.4 1.7 1.0 46.7 2.8 1.1 3.8 1.5 3.2 1.2 2.2 4.4 2.5 3.0 1.7 4.6 2.0 12.3 1.6 4.1 1.6 2.1 5.9 2.7 2.5 2.7 1.6 1.6 1.9 0.0 1.4 0.5 4.1 8.6 6.6 9.4 1.4 1.6 81.6 6.6 1.4 2.9 3.6 8.7 8.4 3.5 15.7 2.9 3.8 1.3 7.8 3.4 4.2 11.1 4.8 2.9 8.4 9.1 1.1 11.5 7.9 1.7 1.9 4.0 0.5 0.9 3.5 3.5 11.8 1.6 4.4 6.2 6.3 3.3 11.0 9.4 2.0 9.5 7.7 2.6 2.2 6.6 5.6 4.7 9.5 11.7 1.0 10.1 2.6 8.6 2.0 6.9 25.9 4.1 4.4 6.6 4.6 23.9 3.9 1.4 3.7 0.0 0.1 0.0 0.6 1.9 1.1 2.7 0.5 0.4 1.6 0.2 0.1 0.9 1.6 0.0 1.9 0.0 1.4 0.5 2.4 2.9 6.3 3.3 2.3 2.8 1.9 1.9 2.8 1.6 0.0 1.1 0.8 1.0 4.2 2.4 2.8 0.0 0.0 2.3 0.0 0.0 112.5 0.0 0.4 7.1 1.1 1.7 0.0 0.6 1526.8 4.8 1.9 0.0 0.0 37.5 3.2 2.9 1.3 0.3 2.6 1.1 1.1 1.7 0.0 2.7 1.8 1.0 2.9 2.1 0.2 0.8 6.5 3.1 14.1 19.5 5.3 96.8 2.2 3.8 2.4 CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358955-43363203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.0;testis: 73.2" "Cell type enhanced" "Detected in many" 11 "Early spermatids: 97.6;Erythroid cells: 70.0;Extravillous trophoblasts: 127.9;Spermatocytes: 74.9;Spermatogonia: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.5;memory CD4 T-cell: 3.3;memory CD8 T-cell: 3.6;NK-cell: 9.8;T-reg: 11.2" "Group enriched" "Detected in many" 9 "B-cells: 4.5;NK-cells: 9.8;T-cells: 11.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Nucleoplasm, Cytosol" "CAB004525: AB_628089, HPA045842: AB_2679470, HPA055288: AB_2682773" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-2)" "unprognostic (2.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.00e-8)" "unprognostic (9.06e-3)" "unprognostic (1.17e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (8.55e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" 1.3 1.2 0.6 16.6 1.1 20.2 1.8 0.8 1.3 2.1 6.2 2.8 0.4 5.8 1.1 1.6 17.8 0.4 1.9 1.2 0.9 0.5 2.2 1.2 1.8 13.4 1.1 0.7 0.9 0.5 0.0 0.4 3.9 1.2 0.8 7.0 0.4 2.9 0.4 0.6 4.6 6.4 2.8 1.2 7.8 4.4 73.2 0.7 42.0 1.2 11.7 21.7 1.9 4.2 4.5 0.9 0.8 0.1 9.8 11.2 2.7 52.6 25.7 35.9 23.4 1.2 3.2 34.4 24.4 21.9 71.2 38.0 40.3 43.8 30.5 14.3 22.4 25.1 37.1 39.2 46.6 59.5 23.9 29.0 44.6 25.4 24.9 0.3 31.1 16.3 1.0 2.2 49.4 44.8 6.2 30.1 29.3 20.1 21.0 32.2 20.4 29.9 19.1 45.4 25.1 34.6 43.5 49.3 19.3 17.3 14.0 21.2 10.4 43.1 29.2 13.5 28.8 20.5 39.4 15.6 21.3 50.0 23.6 75.6 16.1 14.3 31.6 15.3 38.8 31.7 0.0 0.1 0.0 0.4 0.0 0.0 4.5 3.3 3.6 0.9 0.9 0.1 0.3 0.8 9.8 0.0 0.2 11.2 2.7 0.6 1.1 0.8 1.3 0.9 0.5 1.1 0.7 1.2 0.7 0.0 0.6 16.2 2.0 9.3 0.0 0.7 0.0 2.7 1.2 0.0 0.0 13.4 0.0 2.1 97.6 0.7 3.2 70.0 0.3 127.9 4.1 2.0 0.0 1.0 30.9 0.0 0.0 8.0 5.0 7.0 2.6 5.2 0.0 2.8 2.9 0.2 0.7 0.0 1.8 2.1 2.6 0.0 1.4 74.9 48.1 7.3 8.9 1.3 15.5 2.6 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 4.5;NK-cells: 9.3;T-cells: 15.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Uncertain "Vesicles,Mitotic spindle" Yes Yes Vesicles "Mitotic spindle" "HPA038892: AB_2676258, HPA038893: AB_2676259, HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 12.1 8.7 15.1 27.7 23.3 26.0 28.8 49.6 21.1 13.0 14.7 12.8 4.6 14.9 17.0 10.3 11.7 13.0 18.6 7.5 15.7 12.5 13.3 11.0 33.0 42.8 21.9 12.5 17.3 5.7 7.5 21.0 30.3 13.8 11.0 12.0 7.7 7.4 10.2 6.2 19.8 16.8 14.8 14.7 24.5 14.1 6.3 22.3 33.3 18.7 20.8 31.6 15.3 16.3 4.5 1.3 1.5 1.8 9.3 15.5 5.9 29.0 62.7 8.4 13.9 10.3 10.1 4.2 14.4 21.6 24.1 18.0 10.9 42.1 20.3 6.2 14.7 59.6 42.5 11.3 23.9 11.4 7.8 12.2 10.9 20.1 13.1 41.2 8.4 5.6 9.9 19.2 22.3 26.4 8.2 13.3 10.2 7.0 53.5 14.2 23.3 26.3 12.3 6.2 19.9 26.8 13.8 23.8 14.5 16.4 2.7 6.0 13.1 34.1 32.6 16.7 7.5 11.0 4.4 11.0 12.9 15.7 23.4 19.0 13.1 20.6 8.2 6.6 8.3 12.4 1.5 1.4 0.0 13.6 1.8 12.7 3.5 13.6 13.7 1.3 4.5 11.4 13.2 0.1 9.3 0.9 0.7 15.5 5.9 15.1 23.3 49.6 21.1 15.7 12.5 21.9 12.5 13.8 22.3 8.9 23.7 9.0 5.5 10.0 13.9 6.8 7.6 0.0 3.4 7.0 2.0 5.3 0.0 7.8 0.5 24.0 3.8 23.3 4.2 14.2 13.6 4.7 1.1 11.6 24.4 3.2 7.5 12.9 11.6 1.0 6.6 10.6 16.9 5.4 7.9 8.3 10.4 2.9 8.5 9.4 2.4 0.0 11.3 1.0 11.5 9.8 3.0 25.4 3.5 3.4 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287633-40304657 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" 8 "Erythroid cells: 23.3;Extravillous trophoblasts: 27.7;Spermatogonia: 23.0;Syncytiotrophoblasts: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 6.2" "Group enriched" "Detected in many" 5 "dendritic cells: 6.2;NK-cells: 2.2;T-cells: 3.4" "Cell line enhanced" "Detected in many" "SK-BR-3: 86.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 1.8 2.9 3.1 10.8 2.6 16.8 1.5 2.3 6.0 2.7 5.8 0.8 2.7 5.3 1.9 1.6 9.0 1.3 5.4 1.6 1.9 1.4 1.8 5.1 2.8 10.6 1.0 1.5 1.5 3.6 1.1 1.2 9.4 0.8 1.4 5.6 0.2 3.2 4.1 0.9 2.3 7.9 2.4 1.6 7.7 2.7 14.8 1.2 30.0 1.3 5.0 10.1 4.1 3.0 0.7 6.2 0.2 0.3 2.2 3.4 1.2 25.4 17.6 21.3 15.1 1.1 2.3 19.5 27.8 8.3 24.4 29.5 20.0 11.4 20.6 17.4 5.9 14.1 37.1 18.4 12.6 24.3 10.9 14.5 16.7 21.0 17.9 0.7 22.8 10.3 0.6 0.9 28.2 16.9 2.6 7.3 14.2 30.5 19.3 11.8 13.3 33.1 5.5 17.5 15.1 6.5 24.4 51.9 19.4 4.0 28.7 14.6 13.1 25.3 86.7 8.6 17.4 17.6 19.8 6.1 17.6 25.2 28.8 32.9 8.1 17.5 39.7 15.2 15.1 19.2 0.1 0.3 0.0 1.3 0.0 0.9 0.7 1.2 2.1 1.4 0.7 0.9 2.1 0.2 2.2 0.0 6.2 3.4 1.2 3.1 2.6 2.3 6.0 1.9 1.4 1.0 1.5 0.8 1.2 0.0 1.3 2.2 1.1 3.8 0.0 0.6 0.0 0.0 1.2 0.0 0.0 12.0 0.0 1.2 1.4 0.5 1.1 23.3 0.6 27.7 2.4 1.1 0.0 0.9 6.8 0.0 0.0 1.8 1.3 0.2 2.6 1.3 0.0 0.0 1.7 0.3 1.2 2.9 0.7 0.2 0.3 12.9 1.0 11.4 23.0 1.4 14.0 2.5 4.6 2.0 CDCA2 "PPP1R81, Repo-Man" ENSG00000184661 "Cell division cycle associated 2" Q69YH5 8 25458997-25507920 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 38.8;testis: 17.7" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 22.0;Early spermatids: 29.6;Extravillous trophoblasts: 12.3;Late spermatids: 14.4;Sertoli cells: 12.9;Spermatocytes: 45.9;Spermatogonia: 28.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.6;T-reg: 1.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026293, HPA030049" Enhanced Supported Nucleoplasm Yes Yes Nucleoplasm "HPA026293: AB_1846384, HPA030049: AB_10600862" "unprognostic (2.12e-1)" "unprognostic (4.75e-3)" "prognostic favorable (9.62e-4)" "unprognostic (2.92e-2)" "unprognostic (9.69e-2)" "unprognostic (3.56e-2)" "unprognostic (2.50e-5)" "unprognostic (1.47e-3)" "unprognostic (6.06e-2)" "unprognostic (2.91e-3)" "unprognostic (1.32e-3)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.30e-14)" "unprognostic (1.36e-2)" "unprognostic (4.02e-1)" "unprognostic (1.91e-1)" "unprognostic (5.30e-2)" 0.8 0.5 0.3 11.3 0.5 5.5 0.6 0.3 0.3 0.7 3.3 0.2 0.0 1.3 0.5 0.2 2.8 0.3 0.1 0.6 0.3 0.3 0.5 0.5 0.6 4.4 0.4 0.2 0.4 0.3 0.0 0.4 3.3 0.3 0.5 2.0 0.1 0.7 0.0 0.4 1.0 3.3 0.6 1.0 3.9 0.8 17.7 0.4 38.8 0.4 3.5 5.9 0.6 1.0 0.7 0.0 0.0 0.0 2.6 1.9 0.8 14.8 14.1 13.1 10.9 1.1 2.0 8.7 16.7 9.9 14.6 14.6 12.0 6.8 17.6 7.2 6.9 15.8 13.6 18.2 8.5 21.6 6.6 5.2 18.0 10.2 6.4 0.3 8.0 8.8 1.1 0.5 10.2 6.9 1.4 10.5 10.6 14.2 20.4 13.3 5.8 22.4 3.8 13.4 10.3 6.2 11.6 14.5 6.4 4.1 8.1 5.5 5.9 14.1 6.8 6.6 6.6 7.5 3.9 7.2 10.9 17.5 20.5 15.4 3.4 6.9 18.7 7.8 10.5 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.1 0.0 0.1 0.1 0.0 0.0 2.6 0.0 0.0 1.9 0.8 0.3 0.5 0.3 0.3 0.3 0.3 0.4 0.2 0.3 0.4 0.0 0.6 0.8 0.5 1.0 0.4 22.0 0.0 1.4 0.0 0.0 0.0 1.3 0.0 0.2 29.6 0.0 0.0 0.0 0.0 12.3 0.4 0.4 0.0 0.0 3.3 0.0 0.0 1.3 1.9 14.4 1.1 1.2 0.0 1.0 0.1 0.0 0.2 0.0 0.0 0.5 0.3 12.9 0.7 45.9 28.1 0.6 1.4 1.9 1.2 0.4 CDCA5 ENSG00000146670 "Cell division cycle associated 5" Q96FF9 11 65066300-65084164 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 27.4;lymphoid tissue: 39.9;testis: 27.9" "Group enriched" "Detected in many" 5 "Early spermatids: 41.6;Extravillous trophoblasts: 30.6;Late spermatids: 84.2;Spermatocytes: 40.4;Spermatogonia: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "NK-cell: 5.8;T-reg: 4.2" "Group enriched" "Detected in many" 4 "NK-cells: 5.8;T-cells: 4.2" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023691, HPA076007" Enhanced Enhanced Nucleoplasm Yes Yes Nucleoplasm "HPA023691: AB_1846392, HPA076007: " "unprognostic (3.14e-2)" "unprognostic (4.20e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.15e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.21e-6)" "unprognostic (1.41e-3)" "unprognostic (7.55e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (8.72e-6)" "unprognostic (2.16e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.55e-3)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (8.97e-2)" 1.3 1.3 1.1 12.3 1.1 27.4 4.3 1.0 2.8 1.6 3.8 0.6 0.0 3.3 0.9 1.4 7.9 0.7 1.4 1.3 1.1 0.9 1.3 1.3 1.9 9.5 1.1 0.5 0.8 0.7 0.2 0.7 5.5 1.3 0.9 4.7 0.1 1.5 0.1 0.7 2.4 3.6 1.7 0.7 5.7 2.1 27.9 0.2 39.9 0.7 6.6 9.9 1.5 2.3 1.2 0.8 0.3 0.5 5.8 4.2 1.4 30.7 17.6 16.9 14.3 1.1 1.8 14.1 22.0 9.2 25.8 20.6 18.0 18.7 28.0 12.7 7.1 30.4 21.3 27.3 12.1 25.2 28.0 11.9 25.2 12.8 15.1 0.1 26.8 20.4 0.6 1.1 24.1 11.2 2.7 7.8 33.6 28.5 51.8 15.7 25.5 37.8 27.7 26.6 15.2 21.4 33.2 18.7 26.7 5.3 11.8 22.0 16.5 14.1 20.2 14.9 11.0 26.0 13.2 4.9 23.4 24.2 24.6 24.4 26.2 41.5 45.6 9.4 16.6 24.1 0.0 0.2 0.3 0.8 0.0 0.1 0.7 1.1 0.6 0.8 1.2 0.1 0.8 0.1 5.8 0.5 0.7 4.2 1.4 1.1 1.1 1.0 2.8 1.1 0.9 1.1 0.5 1.3 0.2 0.0 0.3 0.8 0.8 3.4 0.8 0.8 0.0 0.0 1.2 0.0 2.0 3.7 1.7 0.9 41.6 0.9 0.9 0.0 0.7 30.6 1.8 0.4 3.5 0.0 9.5 1.6 0.0 1.3 2.8 84.2 2.6 1.9 0.0 3.6 2.3 0.8 0.5 0.0 1.4 0.3 0.2 0.0 0.3 40.4 22.0 0.9 3.1 1.9 2.8 1.0 CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692418-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 19.0;lymphoid tissue: 51.6;testis: 44.7" "Cell type enhanced" "Detected in many" 16 "Extravillous trophoblasts: 20.9;Spermatocytes: 82.1;Spermatogonia: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" 1.2 1.4 0.9 12.9 1.7 19.0 1.7 0.8 1.6 1.8 6.0 1.1 0.7 5.3 1.4 1.3 9.6 0.7 2.4 0.8 0.9 0.9 1.3 1.5 2.0 12.2 1.8 1.3 0.9 1.0 0.1 0.8 3.7 1.3 1.0 7.7 0.7 2.1 1.0 0.9 4.0 5.4 1.6 1.2 5.4 3.5 44.7 1.7 51.6 0.9 6.5 14.6 1.6 2.9 2.8 1.8 4.5 5.0 6.3 8.9 2.5 28.4 12.4 23.5 17.0 1.0 2.0 15.8 21.5 10.8 38.0 27.0 19.4 21.3 34.6 8.7 13.7 15.3 16.2 27.0 14.2 40.4 23.0 12.1 31.1 13.3 15.3 0.2 29.9 16.1 0.8 1.0 21.4 19.0 4.3 16.8 24.9 26.2 37.2 27.4 12.7 27.5 18.4 27.2 16.6 17.2 26.9 32.1 19.8 8.6 11.9 20.9 9.2 23.6 11.1 14.5 21.1 16.3 11.4 10.1 18.7 19.9 10.7 33.5 25.3 32.9 47.2 8.8 27.8 21.4 0.0 1.1 1.8 2.5 2.2 4.5 2.8 5.7 3.3 1.0 2.5 1.9 3.8 4.5 6.3 5.0 1.8 8.9 2.5 0.9 1.7 0.8 1.6 0.9 0.9 1.8 1.3 1.3 1.7 0.0 0.3 9.3 0.8 3.0 1.1 0.4 5.1 8.1 0.0 0.0 0.0 2.2 0.0 1.1 0.8 0.2 4.2 0.0 0.6 20.9 0.9 0.6 0.0 1.0 9.5 1.6 3.5 1.8 3.1 2.2 1.4 4.6 1.7 2.8 5.1 0.0 1.6 4.9 1.1 0.5 0.8 19.4 0.0 82.1 41.4 2.4 2.4 3.2 6.3 0.9 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Yes Yes Nucleoplasm "Midbody, Midbody ring" "HPA007451: AB_2732400, HPA059634: AB_2684090, HPA067060: AB_2685772" "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favorable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favorable (3.63e-4)" 12.3 19.9 16.8 16.4 23.8 17.3 10.1 14.8 21.9 11.1 18.3 8.1 16.4 23.4 12.1 21.7 14.4 14.4 19.4 8.7 15.3 12.6 22.2 33.9 11.8 14.0 13.3 19.4 11.3 22.2 21.6 27.7 13.6 15.8 13.6 12.6 8.1 17.2 8.9 17.5 14.1 20.7 9.0 10.7 15.9 19.0 8.7 13.6 8.0 27.1 10.1 12.1 10.8 14.5 7.8 14.5 3.4 15.3 15.2 13.3 8.8 14.7 9.6 7.7 3.1 3.2 6.1 8.1 12.2 6.9 8.7 2.9 7.4 11.2 13.1 6.2 10.5 5.4 10.3 3.3 17.0 5.5 2.9 8.1 5.1 10.8 0.8 13.4 8.3 9.4 7.5 5.7 5.5 8.3 5.8 15.1 8.7 13.4 1.8 9.9 19.2 10.0 23.8 15.8 16.0 7.3 14.6 10.5 18.4 15.6 11.7 7.6 16.5 15.3 7.1 3.6 9.1 16.7 13.2 13.4 5.9 15.3 6.1 8.3 6.6 3.6 4.0 9.0 14.3 8.4 3.2 11.7 3.4 12.9 15.3 10.9 6.8 11.4 8.9 14.5 7.8 13.3 10.9 1.5 15.2 11.2 10.0 8.8 8.8 16.8 23.8 14.8 21.9 15.3 12.6 13.3 19.4 15.8 13.6 11.9 28.2 16.7 22.2 13.7 17.3 4.8 45.9 18.7 9.1 26.2 23.6 25.3 36.5 23.6 5.0 17.5 42.9 0.0 11.0 16.4 18.6 26.1 9.2 37.6 16.3 17.5 65.1 19.6 16.7 5.4 22.2 13.0 18.6 14.4 38.5 10.3 14.2 35.1 11.7 45.1 33.8 6.5 11.3 23.1 29.8 13.6 23.3 17.5 50.1 18.6 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664588 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 19.5;lymphoid tissue: 67.5" "Cell type enhanced" "Detected in many" 20 "Erythroid cells: 303.7;Extravillous trophoblasts: 74.0;Spermatogonia: 88.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 1.6 1.5 1.0 10.7 1.3 19.5 1.1 0.4 0.9 2.1 5.6 0.3 0.0 4.6 1.2 1.7 9.4 0.8 0.4 1.7 0.6 0.6 1.0 0.8 3.2 6.2 0.6 0.5 1.4 0.6 0.0 0.4 6.4 0.8 0.7 4.5 0.4 1.9 0.0 0.5 4.7 6.4 1.6 1.5 3.8 2.3 9.4 0.6 67.5 0.6 7.6 7.6 1.4 2.9 0.3 0.3 0.0 0.0 0.7 1.9 0.2 32.6 18.5 39.9 20.8 1.5 2.0 15.6 20.2 8.3 12.2 12.0 14.7 20.2 31.1 12.0 11.2 11.0 20.3 24.6 13.2 20.7 27.1 15.4 25.5 28.4 20.9 0.2 36.1 14.0 0.7 1.0 17.5 20.2 3.5 12.7 14.3 23.0 18.6 21.7 12.4 21.3 14.4 35.3 9.8 8.2 22.7 56.4 10.2 11.9 8.1 18.7 25.5 27.3 18.2 10.5 22.2 21.7 13.8 16.7 22.1 26.0 18.3 41.7 14.3 15.4 29.9 9.6 26.1 19.5 0.0 0.0 0.0 0.4 0.0 0.1 0.2 1.4 0.4 0.3 0.3 1.9 0.8 0.0 0.7 0.0 0.3 1.7 0.2 1.0 1.3 0.4 0.9 0.6 0.6 0.6 0.5 0.8 0.6 0.0 1.9 40.2 1.2 8.2 3.2 1.9 2.5 26.8 14.8 0.0 0.0 9.1 0.0 1.8 32.4 2.8 1.3 303.7 0.4 74.0 7.7 1.0 1.1 1.9 26.4 1.6 0.0 9.8 11.2 9.4 1.1 9.9 1.7 0.0 5.3 1.1 0.5 0.0 2.8 0.0 2.8 0.0 0.3 20.9 88.3 4.8 4.2 10.9 15.5 0.9 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496632-93529092 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.9;testis: 19.3" "Cell type enhanced" "Detected in many" 13 "Early spermatids: 15.9;Extravillous trophoblasts: 14.7;Hofbauer cells: 10.9;Spermatocytes: 35.6;Spermatogonia: 19.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 9 "T-reg: 4.4" "Lineage enriched" "Detected in single" 24 "T-cells: 4.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023430 Approved Supported "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 3.2 1.4 0.5 12.1 0.4 3.1 3.6 0.3 0.6 2.0 5.2 0.3 0.2 4.6 0.8 1.5 11.6 0.6 2.5 0.7 0.4 0.5 1.5 0.7 4.4 10.1 0.6 0.2 0.8 0.6 0.0 0.7 3.8 0.5 0.8 6.5 0.4 2.3 0.2 0.7 3.0 5.2 3.5 1.1 4.8 3.2 19.3 0.3 52.9 0.7 10.8 11.0 2.7 3.3 0.1 0.1 0.0 0.0 0.0 4.4 0.0 51.9 20.8 13.8 17.6 1.5 3.2 7.7 28.6 20.3 27.2 28.2 22.1 28.0 13.9 12.7 18.5 18.3 29.7 16.7 14.0 32.7 41.8 8.7 5.2 12.9 7.5 0.1 9.0 12.2 0.7 1.0 29.0 35.4 8.1 25.0 23.1 4.7 26.4 30.7 12.0 23.7 13.7 5.4 16.2 15.2 10.3 22.7 7.6 12.3 6.5 5.7 8.0 22.0 6.8 17.3 11.0 17.9 9.2 15.6 17.3 24.2 23.6 46.9 11.8 16.0 17.0 13.5 34.0 15.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.4 0.0 0.5 0.4 0.3 0.6 0.4 0.5 0.6 0.2 0.5 0.3 0.0 2.2 0.8 0.6 3.2 0.0 0.4 5.1 0.0 0.0 0.0 0.0 0.9 0.0 0.6 15.9 0.0 0.3 0.0 0.2 14.7 0.4 0.1 0.0 0.2 10.9 0.0 0.0 2.5 4.1 3.8 0.3 5.4 0.0 0.0 1.4 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 35.6 19.5 1.1 1.3 1.9 2.3 0.9 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736607-112764677 "Disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.4;lymphoid tissue: 38.3" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 8.9;Spermatocytes: 31.7;Spermatogonia: 32.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Mitotic spindle,Cytosol" Yes Yes "Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 1.5 0.7 0.6 9.2 0.6 13.4 1.3 0.7 0.6 0.6 1.8 0.0 0.3 1.5 0.5 1.4 3.8 0.7 0.1 2.3 0.6 0.5 0.7 0.7 1.2 5.3 0.6 0.2 0.6 0.6 0.0 0.5 3.2 0.2 0.6 2.4 0.0 1.0 0.0 0.6 1.5 2.4 0.9 0.6 2.2 0.9 9.0 0.1 38.3 0.6 5.9 6.0 0.9 0.7 1.0 0.8 1.8 0.7 1.6 1.8 0.4 20.1 4.0 15.9 7.2 0.9 1.5 3.2 16.7 13.9 17.4 16.6 3.8 5.9 13.8 6.9 6.5 21.7 7.8 9.1 8.8 29.3 19.2 4.0 23.0 5.6 3.2 0.0 10.8 13.8 0.4 0.8 21.8 12.4 4.5 7.9 10.1 6.1 20.2 14.1 2.9 13.1 4.1 6.8 8.6 13.2 9.5 16.7 3.6 2.9 7.9 8.8 5.5 6.8 5.6 5.8 6.2 5.5 5.0 5.6 19.3 15.0 15.3 12.2 4.3 8.4 11.8 8.3 7.8 30.2 0.8 0.5 0.7 0.5 0.7 0.4 0.9 1.2 1.1 0.5 1.0 0.5 0.7 1.8 1.6 0.7 0.8 1.8 0.4 0.6 0.6 0.7 0.6 0.6 0.5 0.6 0.2 0.2 0.1 3.0 1.1 0.8 1.6 3.0 0.0 0.4 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.5 1.5 0.0 0.0 0.0 0.3 8.9 0.4 0.3 0.0 0.0 5.4 0.0 0.0 1.8 2.1 0.8 0.0 1.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 31.7 32.2 1.5 0.8 1.5 1.0 0.9 CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769967 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 12.6;lymphoid tissue: 30.4;testis: 10.0" "Group enriched" "Detected in many" 5 "Extravillous trophoblasts: 33.9;Rod photoreceptor cells: 96.1;Spermatocytes: 71.5;Spermatogonia: 133.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in single" 12 "basal ganglia: 7.0" "Low region specificity" "Detected in all" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Nucleoplasm, Golgi apparatus" "HPA026305: AB_2671833, HPA026312: AB_2671837" "unprognostic (4.75e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-3)" "unprognostic (3.54e-2)" "unprognostic (6.82e-2)" "unprognostic (1.62e-2)" "unprognostic (1.18e-6)" "unprognostic (3.99e-3)" "unprognostic (2.08e-3)" "unprognostic (1.63e-2)" "unprognostic (8.71e-6)" "unprognostic (3.23e-2)" "unprognostic (7.61e-6)" "prognostic favorable (4.92e-4)" "unprognostic (5.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" 1.5 0.8 0.9 11.5 1.0 12.6 1.7 0.3 3.6 0.9 2.1 0.1 0.0 1.0 0.5 0.9 2.9 0.5 2.8 0.6 1.1 0.6 1.0 0.7 1.9 6.0 0.6 0.1 0.5 0.5 0.3 0.4 4.3 0.7 0.5 2.7 1.9 1.0 0.0 0.4 1.2 3.4 1.0 0.8 4.4 1.1 10.0 0.5 30.4 0.5 4.2 6.6 0.9 1.2 0.9 0.9 3.4 1.1 1.3 1.6 1.1 8.7 7.3 15.9 8.4 1.1 2.1 5.9 18.0 5.0 13.2 17.7 11.5 8.2 18.7 5.8 4.8 9.6 8.8 15.5 6.2 20.7 12.8 7.0 26.3 15.9 5.1 0.0 21.5 15.5 0.4 0.2 22.7 1.6 1.5 7.1 11.2 17.7 13.0 12.6 5.7 22.6 4.9 15.0 6.0 5.2 14.4 24.1 5.6 2.7 14.5 5.9 6.9 15.6 4.8 3.1 11.2 4.1 8.5 5.1 19.0 14.4 11.6 20.0 4.7 11.4 19.7 6.0 15.4 15.3 1.6 1.1 1.1 1.6 0.5 0.5 0.4 1.0 0.8 0.9 0.9 0.4 0.8 3.4 1.3 0.7 0.8 1.3 1.1 0.9 1.0 0.3 3.6 1.1 0.6 0.6 0.1 0.7 0.5 0.0 0.3 1.5 4.6 4.9 7.9 1.1 2.5 0.0 3.4 0.0 11.8 5.5 0.0 1.3 6.2 1.9 0.4 0.0 0.6 33.9 3.9 1.4 1.1 0.0 14.0 1.6 1.2 3.7 3.2 4.9 2.3 6.5 3.3 15.4 1.6 6.6 0.9 1.9 0.4 0.0 96.1 6.5 2.5 71.5 133.3 1.8 8.7 5.1 4.1 2.6 DBF4 "ASK, chif, DBF4A, ZDBF1" ENSG00000006634 "DBF4 zinc finger" Q9UBU7 7 87876216-87909541 "Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11.8;testis: 34.2" "Cell type enhanced" "Detected in many" 12 "Early spermatids: 250.0;Spermatocytes: 291.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042923 Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Nucleoplasm, Nuclear bodies" "HPA042923: AB_2678222" "unprognostic (2.48e-1)" "unprognostic (8.32e-2)" "unprognostic (1.15e-2)" "unprognostic (4.86e-3)" "unprognostic (2.81e-2)" "unprognostic (3.63e-1)" "prognostic unfavorable (4.45e-6)" "unprognostic (1.05e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (1.46e-3)" "unprognostic (1.05e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (6.42e-7)" "unprognostic (1.98e-2)" "unprognostic (2.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" 1.1 1.2 1.4 5.9 2.0 1.8 3.0 1.9 1.9 1.4 2.1 0.0 0.6 1.2 1.2 1.4 1.7 1.1 1.5 1.0 1.5 1.4 1.2 1.1 2.4 5.0 1.3 1.0 3.4 1.3 1.2 1.8 1.4 0.8 1.2 1.2 0.0 1.2 1.1 1.9 1.3 1.5 0.9 1.2 4.6 1.1 34.2 0.7 11.8 1.4 1.9 2.7 1.6 1.1 1.3 0.9 4.0 0.4 0.9 1.6 0.5 1.3 1.4 3.0 3.8 0.7 0.6 0.9 1.4 0.3 1.5 3.0 2.3 0.9 3.1 1.1 0.9 2.6 1.3 3.1 0.8 1.6 2.3 2.1 2.0 1.7 0.5 0.2 2.4 1.6 0.7 0.8 1.7 1.6 0.5 1.3 2.9 1.7 6.5 2.0 2.4 4.2 3.0 3.0 3.1 2.9 1.1 4.7 3.7 1.2 0.2 4.4 2.8 1.9 3.3 1.5 2.5 1.4 2.5 0.6 1.8 2.2 4.7 3.0 3.7 7.7 3.1 1.3 4.4 3.9 4.0 0.4 0.4 1.2 0.3 0.3 0.8 1.1 0.6 0.2 1.3 1.1 1.3 1.1 0.9 0.4 0.9 1.6 0.5 1.4 2.0 1.9 1.9 1.5 1.4 1.3 1.0 0.8 0.7 3.0 13.0 34.9 16.3 13.9 5.8 3.6 0.0 14.7 5.7 8.7 11.8 12.2 3.3 5.4 250.0 8.5 4.5 46.7 12.9 31.0 7.6 10.6 30.1 5.4 13.9 3.2 14.3 7.4 8.8 57.4 14.4 14.2 11.8 9.0 18.6 1.9 10.7 7.0 8.9 4.4 15.5 12.9 8.2 291.4 77.1 11.0 8.0 21.5 15.8 11.4 DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191678 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 65.1" "Cell type enhanced" "Detected in many" 22 "Erythroid cells: 140.2;Spermatocytes: 61.2;Spermatogonia: 32.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 8.3" "Lineage enriched" "Detected in many" 6 "T-cells: 8.3" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005546 Enhanced Supported "Centriolar satellite,Cytosol" Yes Yes "Centriolar satellite, Cytosol" "HPA005546: AB_1078677" "unprognostic (2.24e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.52e-6)" "prognostic unfavorable (7.85e-4)" "unprognostic (6.15e-3)" "unprognostic (3.55e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.06e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.93e-2)" 1.4 0.9 0.3 11.4 0.4 16.2 0.5 0.3 0.5 1.3 3.3 0.2 0.2 2.9 0.9 1.0 8.7 0.3 1.3 0.7 0.2 0.3 1.1 0.8 2.1 10.6 0.3 0.2 0.7 0.4 0.0 0.3 3.3 0.3 0.5 4.1 0.3 1.5 0.2 0.5 1.9 4.1 1.3 0.3 6.6 2.2 13.0 0.2 65.1 0.4 6.4 11.4 1.7 2.4 1.1 0.4 0.4 0.0 1.3 8.3 1.2 37.6 15.0 39.4 17.7 0.9 3.9 12.2 21.9 14.5 32.4 30.9 12.2 20.8 21.9 12.1 12.7 13.0 23.4 25.2 17.5 42.6 26.4 12.4 22.5 14.1 10.5 0.1 22.0 13.8 0.8 0.6 15.2 7.3 5.2 35.6 22.5 18.2 22.0 30.1 18.1 27.7 11.2 20.3 16.8 15.6 21.7 38.1 10.1 10.6 12.2 20.1 11.3 23.3 8.8 8.6 17.5 19.6 8.2 13.8 14.5 38.0 14.0 25.1 5.4 11.7 29.1 10.1 15.7 23.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.1 2.3 0.4 0.1 0.5 0.2 0.4 1.3 0.0 0.0 8.3 1.2 0.3 0.4 0.3 0.5 0.2 0.3 0.3 0.2 0.3 0.2 0.0 0.3 8.5 0.2 1.0 0.0 0.3 0.0 1.4 1.2 0.0 0.0 1.3 0.0 0.4 10.7 0.0 0.2 140.2 0.0 19.8 1.0 0.2 0.0 0.8 8.6 0.0 0.0 1.8 4.5 4.6 0.9 2.2 0.0 0.0 1.3 0.0 0.1 0.0 1.1 0.0 0.0 6.5 0.0 61.2 32.3 0.4 1.6 1.5 2.5 1.1 DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 homolog, MIS12 kinetochore complex component" Q9H410 20 36751791-36773818 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Spermatocytes: 90.5;Spermatogonia: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: AB_1078343, HPA030627: AB_2732460" "unprognostic (3.60e-2)" "prognostic favorable (4.49e-4)" "unprognostic (5.22e-3)" "unprognostic (1.13e-3)" "unprognostic (2.00e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (4.16e-5)" "unprognostic (3.93e-1)" "unprognostic (9.35e-2)" "unprognostic (5.51e-2)" "unprognostic (2.98e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.92e-2)" "unprognostic (2.53e-1)" "unprognostic (2.58e-2)" "unprognostic (2.84e-1)" 6.7 10.4 5.6 15.6 7.4 11.6 8.2 5.4 7.2 5.1 8.6 4.1 9.5 6.3 9.5 12.0 9.1 5.0 8.1 6.2 5.1 4.7 5.8 8.6 6.1 11.0 4.8 3.9 5.3 5.4 3.6 7.6 12.9 5.1 6.5 10.3 10.1 9.7 8.1 4.6 7.3 8.8 5.9 4.1 11.6 7.0 27.2 4.1 21.2 6.3 11.4 13.8 5.8 5.5 10.9 25.4 21.7 5.9 5.6 6.5 3.7 13.0 11.8 13.9 11.1 5.5 7.2 9.2 16.0 13.6 24.6 27.7 20.5 17.0 15.1 10.7 8.7 27.2 17.2 13.0 12.6 23.5 6.6 8.3 29.4 11.3 13.7 1.2 16.8 13.0 2.7 3.6 17.0 5.4 4.0 12.0 16.4 11.4 12.5 16.1 9.3 21.5 13.0 6.5 23.6 20.9 16.9 42.4 10.0 6.2 7.8 14.3 6.5 19.9 20.5 9.7 10.8 20.9 11.3 6.2 22.5 13.7 22.0 17.2 10.5 14.1 17.1 18.9 15.2 16.0 21.7 3.6 7.5 4.4 5.9 4.9 8.8 4.8 5.8 3.9 10.9 5.9 5.5 6.5 5.6 5.0 25.4 6.5 3.7 5.6 7.4 5.4 7.2 5.1 4.7 4.8 3.9 5.1 4.1 6.0 4.1 9.3 10.2 4.4 8.0 4.1 2.5 10.7 10.3 5.2 27.5 42.7 6.6 5.2 6.3 5.8 6.4 0.0 5.6 29.3 7.5 7.5 3.5 4.5 12.6 6.4 2.4 9.8 3.7 5.8 8.1 6.1 1.7 8.2 9.0 4.8 4.7 5.7 7.1 2.9 15.8 0.0 7.2 90.5 91.3 6.4 39.7 6.4 10.5 10.8 DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 10.8;lymphoid tissue: 41.2;testis: 37.2" "Cell type enhanced" "Detected in many" 11 "Early spermatids: 17.8;Erythroid cells: 23.3;Extravillous trophoblasts: 13.2;Spermatocytes: 35.9;Spermatogonia: 19.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory CD8 T-cell: 1.5;T-reg: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028016, HPA032023, HPA032031" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes Nucleoplasm "Nucleoli, Cytosol" "HPA028016: AB_10611958, HPA032023: AB_2674114, HPA032031: AB_2674119" "unprognostic (7.61e-2)" "unprognostic (1.01e-3)" "unprognostic (2.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (8.96e-3)" "unprognostic (2.45e-3)" "unprognostic (8.83e-3)" "unprognostic (2.52e-3)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.71e-9)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" 1.3 0.7 0.4 5.4 0.6 10.8 1.3 0.4 0.5 1.2 2.8 0.3 0.1 1.7 1.0 0.6 4.0 0.4 1.5 0.6 0.4 0.4 0.8 1.0 1.6 4.4 0.4 0.1 0.6 0.5 0.6 0.7 5.4 0.2 0.6 4.2 0.2 1.1 0.1 0.4 1.6 3.3 1.4 0.4 4.6 1.1 37.2 0.1 41.2 0.9 5.7 7.5 0.9 1.6 0.7 0.3 0.0 0.4 0.6 5.2 0.7 12.6 10.8 18.5 9.2 1.1 2.3 9.1 15.9 9.9 15.1 22.5 6.7 11.2 9.6 6.0 6.1 9.7 9.9 24.4 13.4 21.8 11.6 11.7 15.3 14.3 8.1 0.0 20.1 9.6 1.0 0.4 24.4 13.0 2.7 6.9 17.0 18.2 19.6 17.4 5.1 26.8 9.2 21.4 9.6 12.5 21.3 32.7 18.5 4.3 8.8 11.6 18.2 15.1 14.5 6.5 19.7 12.4 9.2 3.7 15.1 11.3 15.6 17.9 7.2 11.2 22.2 7.6 13.3 14.6 0.0 0.0 0.0 0.6 0.4 0.0 0.7 0.8 1.5 0.3 0.1 0.0 0.3 0.0 0.6 0.0 0.0 5.2 0.7 0.4 0.6 0.4 0.5 0.4 0.4 0.4 0.1 0.2 0.1 0.0 0.0 7.8 0.4 2.1 0.0 6.1 2.5 0.0 1.2 0.0 0.0 7.5 0.0 0.2 17.8 1.8 0.5 23.3 0.0 13.2 1.2 0.2 0.0 0.0 3.9 0.0 0.0 1.3 0.3 7.9 1.1 1.0 0.0 0.0 1.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 35.9 19.1 1.5 1.3 1.9 2.9 0.0 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: AB_2670577" "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavorable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 19.6 16.1 15.1 15.1 17.9 29.5 21.4 31.8 21.5 23.1 16.8 16.4 16.2 16.3 29.9 19.8 38.7 37.4 15.2 15.2 17.2 13.9 19.3 16.5 17.2 21.5 12.7 15.8 26.4 14.9 11.6 28.2 19.1 14.0 18.2 16.8 16.5 22.3 20.3 16.2 27.9 19.7 18.9 13.4 21.5 15.4 19.7 13.8 28.7 16.8 16.2 29.3 20.4 27.3 29.9 20.9 42.6 19.1 28.0 37.6 29.2 19.4 8.4 9.1 9.6 16.5 20.7 16.3 14.3 18.7 18.6 19.1 12.1 14.8 25.3 9.2 15.4 16.7 13.6 11.2 28.8 18.0 17.4 11.7 15.5 6.4 18.5 17.3 17.4 14.6 16.7 35.0 16.6 23.1 16.2 20.6 12.4 16.4 14.9 20.6 10.8 16.7 18.6 14.6 18.3 11.7 6.7 24.5 22.7 15.0 16.2 13.5 7.3 13.2 15.8 16.8 11.4 8.4 9.3 11.7 13.3 16.4 15.2 16.8 15.9 12.6 33.4 12.3 17.7 12.9 24.7 19.1 42.6 26.8 16.9 34.6 29.9 31.7 31.6 20.9 28.1 33.9 31.8 29.1 28.0 16.9 15.9 37.6 29.2 15.1 17.9 31.8 21.5 17.2 13.9 12.7 15.8 14.0 13.8 8.9 11.8 34.3 47.9 73.8 9.4 6.9 33.1 26.8 22.7 12.2 3.9 27.8 43.1 24.2 5.9 29.2 13.5 23.3 24.2 35.1 26.6 23.0 41.4 12.9 27.5 4.8 11.5 29.4 22.3 5.6 26.7 20.5 21.9 42.3 19.0 9.3 22.5 17.8 24.1 38.5 13.9 6.5 22.8 23.6 31.8 72.5 32.3 32.4 17.2 54.2 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 23.2;lymphoid tissue: 39.8;testis: 10.3" "Group enriched" "Detected in many" 9 "Erythroid cells: 70.0;Spermatocytes: 30.1;Spermatogonia: 77.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 4.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 1.0 1.7 0.5 7.1 0.5 5.5 1.0 0.4 0.6 1.2 9.6 0.1 0.5 11.9 0.6 1.0 5.0 0.3 1.8 1.1 0.7 0.5 1.6 1.4 1.1 4.2 0.5 0.6 0.6 1.0 0.3 0.3 1.5 0.5 0.5 4.5 0.1 1.4 1.4 0.4 1.1 23.2 0.4 0.8 4.7 2.4 10.3 0.2 39.8 0.5 5.3 5.7 1.0 1.8 1.3 1.9 0.8 1.5 0.9 4.6 0.8 25.1 19.1 8.6 10.4 1.1 1.8 4.8 15.1 6.4 14.1 16.1 6.7 5.0 9.3 8.0 3.9 11.8 13.9 10.4 4.1 21.4 7.2 4.4 11.0 8.6 7.1 0.1 5.6 10.3 0.3 0.4 8.2 2.1 1.4 5.2 7.2 8.8 14.2 8.1 4.9 22.6 2.5 5.8 13.8 6.4 10.0 25.7 6.8 4.6 15.2 3.7 5.5 7.6 9.2 3.8 3.3 6.3 6.2 2.3 8.7 18.0 17.5 11.8 1.9 5.0 11.5 4.8 9.4 12.0 0.1 0.7 0.4 0.3 1.5 0.1 1.3 0.7 1.0 1.9 0.1 0.5 0.4 0.8 0.9 0.4 0.2 4.6 0.8 0.5 0.5 0.4 0.6 0.7 0.5 0.5 0.6 0.5 0.2 0.0 6.6 2.2 0.7 2.1 1.5 1.1 0.0 2.7 5.7 0.0 3.9 1.0 0.0 0.3 3.9 0.1 5.3 70.0 0.0 5.5 0.9 0.2 1.1 1.1 4.5 0.0 1.2 0.6 4.1 0.4 1.7 3.5 0.0 0.0 2.3 0.0 0.1 0.8 0.0 0.0 1.8 6.5 0.3 30.1 77.3 0.5 0.8 2.9 4.0 0.9 FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 83.4" "Cell type enhanced" "Detected in many" 9 "Extravillous trophoblasts: 131.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 83.4;eosinophil: 24.8;intermediate monocyte: 25.1;non-classical monocyte: 37.7" "Group enriched" "Detected in all" 9 "granulocytes: 83.4;monocytes: 37.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" 5.2 3.6 1.7 17.7 4.2 7.4 7.7 1.9 3.9 6.5 8.8 2.0 7.7 10.0 4.0 6.1 22.1 1.9 6.9 4.8 1.7 2.5 4.8 3.9 15.2 18.7 2.1 1.9 2.6 3.5 9.3 5.1 11.1 3.6 11.1 3.4 3.1 12.7 10.5 3.7 39.9 9.2 1.3 1.6 15.1 5.5 2.8 1.3 22.9 7.7 8.0 18.9 7.8 9.7 1.9 5.8 83.4 37.7 1.0 6.4 3.2 12.7 3.4 1.9 3.6 2.2 0.9 13.4 4.0 2.2 2.6 2.3 7.5 8.0 4.1 1.8 2.5 3.6 20.7 1.6 10.5 2.1 3.3 1.1 8.6 2.2 1.9 1.0 2.3 3.0 0.6 13.1 3.5 3.5 0.8 1.7 3.8 4.6 10.3 2.3 7.6 6.5 6.4 2.5 8.2 5.9 6.5 3.4 5.4 1.9 9.2 3.7 4.4 3.4 40.4 1.8 0.8 16.7 3.5 2.2 6.1 4.5 5.5 4.4 3.8 3.2 1.7 0.9 6.1 4.4 83.4 4.4 24.8 2.2 25.1 2.0 1.1 4.0 4.6 5.8 1.9 4.9 4.7 2.5 1.0 37.7 0.6 6.4 3.2 1.7 4.2 1.9 3.9 1.7 2.5 2.1 1.9 3.6 1.3 0.0 6.5 19.9 14.7 29.0 0.2 2.4 5.1 4.0 0.0 10.4 0.0 36.4 1.7 8.3 6.0 5.8 6.9 46.7 5.2 131.1 4.7 17.7 52.8 0.8 17.4 4.8 10.4 18.4 36.5 13.5 3.1 27.8 6.8 6.4 7.5 0.2 10.7 8.0 1.8 2.1 2.5 6.5 5.2 1.9 5.3 32.1 26.2 26.2 7.8 20.9 FAM83D "C20orf129, CHICA, dJ616B8.3" ENSG00000101447 "Family with sequence similarity 83 member D" Q9H4H8 20 38926312-38953106 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.0;smooth muscle: 69.8" "Cell type enhanced" "Detected in many" 22 "Erythroid cells: 23.3;Extravillous trophoblasts: 36.2;Syncytiotrophoblasts: 127.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 1.6;NK-cells: 2.4;T-cells: 4.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049333, HPA060854" Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Mitotic spindle" "Microtubules, Cytokinetic bridge, Cytosol" "HPA049333: AB_2680717, HPA060854: " "unprognostic (7.90e-3)" "unprognostic (4.34e-2)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (5.44e-6)" "prognostic unfavorable (9.69e-4)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (4.73e-5)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.81e-14)" "unprognostic (2.57e-3)" "unprognostic (5.74e-2)" "unprognostic (2.82e-1)" "unprognostic (4.87e-2)" 0.5 0.5 0.5 4.9 0.8 7.9 0.7 0.4 1.2 1.7 29.6 0.4 0.7 3.4 0.8 1.5 39.0 0.2 5.6 1.5 0.5 0.1 2.2 1.4 2.6 1.5 0.3 0.5 0.7 0.2 0.0 0.3 2.2 0.7 7.6 3.6 1.2 3.1 1.0 0.4 4.1 16.2 69.8 0.4 1.0 22.8 3.8 0.2 9.2 0.5 8.6 17.9 24.5 6.4 1.6 0.1 0.0 0.4 2.4 4.6 1.2 31.5 19.5 15.4 12.9 1.7 2.0 27.7 14.2 8.9 28.2 17.3 29.8 14.5 8.0 14.1 9.3 21.9 27.2 21.1 24.4 26.5 2.6 8.3 9.3 15.0 21.4 1.4 4.1 4.9 1.0 1.2 16.2 9.4 3.4 15.4 3.6 8.2 11.6 16.0 17.0 6.3 6.0 12.8 18.4 24.9 6.1 28.5 4.4 8.1 8.1 7.1 11.9 41.5 34.7 6.1 15.0 21.7 4.2 7.3 18.7 23.0 21.2 31.3 3.5 5.4 8.3 8.4 6.1 13.7 0.0 0.0 0.0 0.7 0.4 2.3 1.6 2.4 2.7 0.1 1.6 2.7 3.4 0.0 2.4 0.1 0.0 4.6 1.2 0.5 0.8 0.4 1.2 0.5 0.1 0.3 0.5 0.7 0.2 0.0 2.2 0.0 5.2 2.1 0.0 0.8 0.0 1.4 1.2 0.0 0.0 2.6 0.0 0.0 0.4 0.5 2.6 23.3 0.0 36.2 0.9 0.7 0.0 5.4 4.0 0.0 1.7 1.8 2.1 0.6 0.3 0.4 0.0 0.0 2.2 0.0 0.1 3.7 0.0 4.3 0.0 19.4 2.1 11.1 14.5 1.6 127.6 2.2 2.5 4.3 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296741-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.0;testis: 22.3" "Cell type enhanced" "Detected in many" 18 "Erythroid cells: 93.5;Extravillous trophoblasts: 27.0;Spermatocytes: 47.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 1.1 1.3 0.3 10.4 0.8 10.2 1.3 1.0 1.1 1.2 2.5 0.7 0.1 4.1 1.1 1.3 6.6 0.4 0.4 0.8 1.0 0.3 0.9 0.9 1.3 9.0 0.6 0.4 0.9 0.5 0.0 0.9 2.8 1.8 0.6 2.6 0.7 1.5 0.1 0.3 2.4 3.3 1.0 0.6 4.6 2.4 22.3 0.3 20.0 0.5 5.8 8.8 1.1 2.1 1.4 1.9 3.0 0.2 1.8 1.6 0.9 21.8 10.4 20.5 16.2 0.4 1.2 9.8 19.0 9.0 27.7 22.9 10.8 8.3 20.7 5.0 7.3 12.7 11.5 18.3 4.8 17.8 12.4 19.7 13.8 14.6 8.4 0.0 24.7 16.9 0.2 0.3 11.9 6.1 2.9 11.9 15.0 10.5 26.0 16.5 12.2 22.1 12.1 14.3 9.0 11.7 22.0 23.0 13.5 4.5 4.0 10.6 14.5 18.1 11.8 8.4 9.6 10.0 9.6 9.4 15.8 30.0 12.9 19.9 14.9 7.1 21.0 10.0 11.9 23.0 0.1 0.2 1.5 1.3 0.1 0.4 1.4 0.6 0.6 0.3 0.6 0.4 0.3 3.0 1.8 0.1 1.9 1.6 0.9 0.3 0.8 1.0 1.1 1.0 0.3 0.6 0.4 1.8 0.3 0.0 0.0 0.8 0.6 2.5 0.6 1.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.5 3.9 0.4 0.5 93.5 0.2 27.0 1.1 0.6 0.0 0.5 16.0 0.0 1.2 5.5 6.2 3.8 0.3 3.5 0.0 0.0 2.0 0.2 0.4 0.0 0.7 0.4 0.1 6.5 0.9 47.7 20.4 2.3 1.3 2.9 3.7 1.4 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 27.4;lymphoid tissue: 51.1;testis: 20.9" "Cell type enhanced" "Detected in many" 17 "Early spermatids: 12.4;Erythroid cells: 46.7;Extravillous trophoblasts: 13.7;Spermatocytes: 18.4;Spermatogonia: 12.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 4.2" "Group enriched" "Detected in many" 4 "granulocytes: 1.2;monocytes: 1.3;T-cells: 4.2" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 1.4 0.9 0.1 12.2 0.4 27.4 2.2 0.1 0.7 1.1 3.7 0.3 0.1 2.6 0.6 1.8 8.0 0.3 0.7 1.1 0.1 0.2 1.0 1.2 2.0 8.1 0.2 0.1 0.6 0.4 0.0 0.2 3.1 0.2 0.7 3.6 0.3 1.5 1.0 0.2 2.6 4.8 1.1 0.4 5.8 2.4 20.9 0.1 51.1 0.4 3.0 11.6 1.0 2.8 0.5 0.3 1.2 1.3 0.5 4.2 1.7 17.0 23.1 22.6 10.6 0.8 1.8 14.1 25.6 12.3 18.3 20.0 16.2 18.7 5.3 2.9 10.1 32.6 20.0 18.0 13.3 24.4 12.5 6.8 20.6 18.6 15.7 0.1 16.9 14.2 0.6 0.5 14.9 10.3 5.2 11.4 16.5 17.4 13.3 33.6 17.2 23.7 18.7 19.3 13.4 16.0 18.4 33.9 9.5 9.4 10.3 13.0 8.1 14.8 11.2 10.5 10.8 8.4 13.1 8.3 19.8 21.6 14.5 27.7 12.7 10.0 21.4 11.9 12.5 49.3 0.6 0.2 0.2 0.3 0.2 0.2 0.4 0.7 0.6 0.3 0.5 0.3 0.5 1.2 0.5 1.3 0.2 4.2 1.7 0.1 0.4 0.1 0.7 0.1 0.2 0.2 0.1 0.2 0.1 0.0 0.3 0.8 0.4 1.1 0.0 0.8 0.0 0.0 3.4 0.0 0.0 1.1 0.0 0.0 12.4 0.1 0.9 46.7 0.0 13.7 0.3 0.4 0.0 0.0 5.7 0.0 0.0 2.5 2.4 7.4 0.6 2.1 0.0 0.0 0.7 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.3 18.4 12.9 0.6 1.3 1.3 1.2 0.6 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491945 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.5;testis: 16.7" "Cell type enhanced" "Detected in many" 21 "Early spermatids: 60.3;Erythroid cells: 256.9;Extravillous trophoblasts: 50.4;Spermatocytes: 80.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "T-reg: 4.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 1.6 1.4 0.6 13.4 0.6 11.4 2.4 0.4 0.9 1.7 5.0 0.6 0.6 4.5 0.6 2.3 6.4 0.5 0.9 1.6 0.8 0.7 1.4 1.8 2.5 10.9 1.0 0.4 0.6 1.1 0.6 0.5 6.9 1.1 0.7 5.6 0.4 1.6 0.2 1.4 2.3 4.8 1.4 1.9 8.6 2.6 16.7 0.3 54.5 0.7 5.6 10.8 1.8 2.1 1.2 1.8 0.6 0.7 1.5 4.8 0.8 21.1 13.3 27.2 14.5 1.4 2.7 20.3 20.1 9.8 25.2 22.9 27.0 40.9 35.2 19.2 6.2 34.4 24.5 31.4 19.1 43.1 31.9 9.7 21.0 9.5 13.2 0.4 18.6 19.4 0.7 1.1 23.7 18.6 4.2 14.3 24.2 19.9 28.8 26.2 7.7 19.6 10.6 23.4 14.2 14.6 21.4 36.4 17.6 9.8 5.7 22.7 12.6 29.9 9.4 11.4 13.5 27.7 15.0 9.3 18.1 15.4 14.5 26.9 15.5 25.9 28.4 12.0 28.9 17.4 0.5 0.7 0.0 0.5 0.3 0.9 1.2 1.0 0.6 0.9 0.9 0.4 0.7 0.6 1.5 0.0 1.8 4.8 0.8 0.6 0.6 0.4 0.9 0.8 0.7 1.0 0.4 1.1 0.3 0.0 0.6 15.5 0.8 2.3 0.6 1.7 7.6 4.0 4.5 0.0 0.0 5.1 0.0 0.6 60.3 0.1 1.3 256.9 0.2 50.4 2.4 0.8 0.0 1.7 17.7 0.0 1.2 3.1 3.5 44.1 2.0 4.3 0.0 3.6 1.6 0.0 0.1 0.0 0.7 2.4 0.7 6.5 0.0 80.6 18.5 1.3 3.8 1.0 4.2 0.9 INCENP FLJ31633 ENSG00000149503 "Inner centromere protein" Q9NQS7 11 62123973-62153163 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.1" "Cell type enhanced" "Detected in many" 4 "monocytes: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.9;NK-cell: 4.0" "Group enriched" "Detected in many" 6 "granulocytes: 2.9;NK-cells: 4.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013292, HPA051339, HPA070550" Enhanced Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "CAB013292: AB_2533405, HPA051339: AB_2732566, HPA070550: AB_2686279" "unprognostic (6.31e-2)" "unprognostic (7.29e-2)" "unprognostic (1.65e-3)" "unprognostic (7.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (8.58e-4)" "unprognostic (1.63e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (1.74e-2)" "unprognostic (1.08e-3)" "unprognostic (1.17e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (2.78e-3)" 5.1 5.0 6.9 9.2 8.2 23.8 7.7 19.3 13.6 6.9 6.5 5.7 2.8 9.5 5.7 11.7 22.2 5.3 4.7 4.1 5.9 5.0 3.9 3.8 5.0 14.1 6.9 7.9 5.3 5.4 6.0 3.1 5.7 6.9 4.2 5.3 4.9 10.6 4.6 6.7 9.8 7.5 4.9 5.1 7.5 6.4 12.3 6.4 36.1 8.5 8.5 13.2 5.9 8.6 0.2 0.0 2.9 0.3 4.0 0.5 0.0 27.0 25.9 19.7 16.8 2.6 3.2 10.5 17.0 7.4 15.9 10.2 13.6 18.4 25.1 14.1 5.8 17.6 26.6 19.5 10.3 12.5 22.3 13.5 16.4 25.5 11.1 1.0 18.8 23.4 1.6 2.3 15.3 8.9 2.6 9.5 18.3 17.3 21.0 8.7 22.0 30.3 15.4 21.2 10.5 12.7 28.4 24.8 18.9 4.5 13.6 15.0 16.3 17.1 11.1 10.5 8.2 17.4 6.8 10.6 15.7 20.1 22.4 18.1 11.2 17.2 28.2 8.7 12.4 18.8 2.9 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.2 4.0 0.1 0.0 0.0 0.0 6.9 8.2 19.3 13.6 5.9 5.0 6.9 7.9 6.9 6.4 3.0 2.9 2.2 0.8 4.9 1.9 0.9 0.0 4.0 5.7 0.0 0.0 1.6 0.0 1.7 0.8 0.8 1.3 0.0 2.1 6.0 0.8 1.0 3.5 0.9 3.5 0.0 0.0 0.0 0.8 0.2 2.6 2.5 3.3 8.2 2.0 2.3 1.7 1.5 1.4 0.3 2.2 0.0 0.4 6.9 5.8 2.9 1.8 2.5 1.7 1.0 IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.8;intestine: 13.0" "Cell type enhanced" "Detected in some" 14 "Cholangiocytes: 5.1;Late spermatids: 16.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "T-reg: 2.6" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim" Yes Yes "Nucleoli rim" Nucleoplasm "HPA030142: AB_10600108, HPA030143: AB_10601104" "unprognostic (9.99e-3)" "unprognostic (5.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.55e-3)" "unprognostic (1.52e-1)" "unprognostic (4.69e-3)" "prognostic unfavorable (8.94e-6)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.30e-2)" "unprognostic (6.81e-2)" 3.2 1.2 0.3 5.4 0.3 14.8 0.6 0.3 0.8 1.4 10.1 0.4 1.3 7.0 1.1 3.7 9.8 0.3 1.8 1.8 0.4 0.2 1.5 1.1 2.6 1.4 0.3 0.3 0.5 0.4 0.0 0.3 6.5 0.8 0.8 5.5 0.4 1.8 0.3 0.5 3.8 13.0 2.9 1.5 1.5 5.1 6.8 0.3 12.2 0.4 3.1 7.3 0.9 3.1 0.2 0.9 0.5 0.3 0.6 2.6 0.0 23.5 11.4 10.7 7.5 0.6 1.7 5.2 17.5 11.7 17.2 15.5 13.0 21.8 2.1 6.5 10.3 9.1 22.5 7.3 9.0 15.5 0.0 6.5 3.1 22.4 6.4 0.1 3.8 0.0 0.5 1.0 14.4 21.3 4.2 10.0 5.1 6.3 3.4 12.6 12.4 2.2 5.5 7.8 23.3 11.5 7.6 12.0 2.4 4.4 8.1 6.8 10.5 15.9 18.7 6.4 13.1 14.9 10.3 6.5 15.6 18.7 12.7 20.6 1.6 0.8 1.0 5.2 6.1 17.6 0.5 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.6 0.1 0.1 0.1 0.2 0.6 0.3 0.9 2.6 0.0 0.3 0.3 0.3 0.8 0.4 0.2 0.3 0.3 0.8 0.3 0.0 0.0 0.5 0.0 1.1 0.0 0.8 5.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 4.7 0.0 1.1 0.0 0.0 3.1 0.5 0.2 0.0 0.0 3.4 0.0 1.2 4.3 0.3 16.8 0.3 2.2 0.0 0.0 2.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 3.8 2.4 0.9 0.7 0.0 2.9 0.4 KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92593286-92655395 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 74.2" "Group enriched" "Detected in many" 4 "Early spermatids: 9.6;Erythroid cells: 23.3;Extravillous trophoblasts: 11.2;Hofbauer cells: 6.7;Spermatocytes: 24.7;Spermatogonia: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes Cytosol "Mitotic spindle" "CAB017617: AB_2131098, HPA006916: AB_1848033, HPA010093: AB_2668281, HPA010568: AB_1848034" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.35e-2)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (8.19e-7)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (6.59e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.35e-3)" "unprognostic (7.23e-2)" "unprognostic (9.08e-2)" "unprognostic (2.01e-1)" 2.3 1.6 1.0 20.2 2.6 14.3 1.6 0.7 1.5 2.4 4.6 0.7 0.5 3.7 1.4 1.9 11.5 0.8 2.6 2.0 1.1 1.2 1.1 1.1 2.8 12.1 1.0 1.0 1.1 1.1 0.5 0.7 3.1 1.4 1.0 5.4 0.5 2.7 0.2 0.6 4.2 4.4 1.6 1.8 5.2 2.7 10.5 1.1 74.2 1.2 7.5 13.4 2.2 3.8 2.4 0.9 2.5 1.2 3.5 3.9 1.0 31.0 13.9 31.4 29.2 2.3 3.5 7.8 22.4 19.6 24.9 24.8 12.1 20.6 34.4 11.5 10.4 10.6 22.5 22.4 11.4 29.3 20.5 12.9 21.5 13.3 12.7 0.4 34.6 20.1 1.1 1.0 19.2 18.0 5.8 15.4 14.4 15.2 40.2 18.8 12.4 29.4 19.5 12.5 12.6 9.6 31.7 31.1 12.1 6.5 9.1 9.6 13.8 17.5 7.9 9.1 11.2 21.5 11.1 8.7 11.4 16.4 11.6 29.4 11.2 17.3 35.4 9.2 25.0 15.4 2.5 0.5 0.5 0.4 1.2 1.1 2.4 1.4 1.9 0.9 1.0 0.5 0.7 1.4 3.5 0.4 0.4 3.9 1.0 1.0 2.6 0.7 1.5 1.1 1.2 1.0 1.0 1.4 1.1 0.0 1.3 0.8 0.8 2.6 1.3 1.4 0.0 4.0 3.4 1.8 0.0 1.5 1.7 0.4 9.6 0.3 0.4 23.3 0.6 11.2 1.6 0.8 0.0 0.0 6.7 0.0 0.0 2.5 2.5 3.9 0.9 2.6 0.0 1.0 1.9 0.8 0.3 0.0 0.7 0.5 0.4 0.0 1.2 24.7 25.8 2.9 1.3 3.8 2.9 0.9 KIF18A "DKFZP434G2226, PPP1R99" ENSG00000121621 "Kinesin family member 18A" Q8NI77 11 28020620-28108308 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 31.3;testis: 16.9" "Cell type enhanced" "Detected in many" 19 "Early spermatids: 22.1;Erythroid cells: 23.3;Spermatocytes: 76.3;Spermatogonia: 16.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 6.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA039312, HPA039484" Approved Supported "Microtubules,Cytokinetic bridge" Yes Yes "Microtubules, Cytokinetic bridge" "HPA039312: AB_10794087, HPA039484: AB_10795252" "unprognostic (3.79e-1)" "unprognostic (2.63e-1)" "unprognostic (7.09e-3)" "unprognostic (3.80e-2)" "unprognostic (6.56e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-7)" "unprognostic (2.43e-3)" "unprognostic (2.04e-3)" "unprognostic (1.23e-2)" "unprognostic (1.72e-4)" "unprognostic (4.41e-2)" "unprognostic (0.00e+0)" "unprognostic (7.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-1)" 0.9 0.5 0.6 3.9 0.8 7.9 0.6 0.9 0.9 0.8 2.1 0.3 0.0 1.5 0.5 0.8 3.1 0.5 0.4 0.5 0.7 0.5 1.8 0.5 1.5 4.8 0.5 0.0 0.6 0.5 0.0 0.6 3.4 0.8 0.5 2.2 1.3 0.9 1.6 0.8 1.3 1.9 0.6 0.9 2.7 1.0 16.9 0.2 31.3 2.8 2.0 4.9 1.0 1.2 2.3 0.7 6.4 0.4 2.8 2.2 0.4 12.5 12.6 12.8 8.9 0.4 1.8 4.3 13.1 6.1 20.9 22.0 4.2 5.1 10.6 4.7 6.7 11.4 12.7 10.9 5.1 29.4 10.5 6.6 6.9 8.6 5.3 1.0 10.1 6.3 3.3 0.6 7.3 8.6 3.7 8.0 8.8 10.9 9.3 11.8 6.6 10.2 7.5 6.3 8.2 5.2 8.0 30.6 5.2 5.9 3.7 7.7 5.9 10.9 5.2 3.6 8.2 11.1 3.1 4.6 16.7 13.0 15.6 17.0 3.7 8.7 10.7 10.0 7.5 11.7 6.4 0.0 0.8 0.2 0.4 0.8 2.3 0.9 0.5 0.7 1.0 0.8 0.3 0.0 2.8 0.1 0.6 2.2 0.4 0.6 0.8 0.9 0.9 0.7 0.5 0.5 0.0 0.8 0.2 3.0 0.0 6.0 1.0 2.1 0.2 0.4 0.0 2.7 3.4 0.0 5.9 2.6 0.0 0.5 22.1 0.3 0.5 23.3 0.8 6.4 0.4 0.2 4.6 0.0 1.9 0.0 1.7 1.3 1.0 4.0 0.6 1.1 0.0 1.8 0.9 0.3 0.4 0.0 0.4 0.5 1.6 0.0 0.3 76.3 16.2 0.9 1.4 3.2 1.4 0.1 KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947711 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 12.3;lymphoid tissue: 34.7" "Cell type enhanced" "Detected in some" 10 "Cardiomyocytes: 1.6;Extravillous trophoblasts: 3.6;Hofbauer cells: 1.9;Kupffer cells: 1.8;Spermatogonia: 2.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Nucleoplasm, Microtubule ends" "Nuclear bodies, Cytosol" "HPA024205: AB_1852472" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (4.61e-2)" "unprognostic (1.13e-2)" "unprognostic (4.17e-1)" "unprognostic (7.27e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (3.34e-3)" "prognostic unfavorable (6.90e-4)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (8.18e-2)" "unprognostic (0.00e+0)" "unprognostic (4.69e-3)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" 0.7 0.6 0.5 8.2 0.4 12.3 0.4 0.4 0.5 0.9 1.6 0.3 0.7 2.9 0.5 0.6 3.2 0.3 1.3 1.5 0.5 0.5 0.5 0.7 0.8 5.9 0.6 0.1 0.6 0.4 0.0 0.4 1.9 0.2 0.5 1.5 0.1 0.7 0.1 0.4 2.9 2.5 0.8 0.4 1.7 1.5 3.8 0.1 34.7 0.4 2.7 7.6 0.7 1.1 1.1 0.8 2.0 0.6 1.0 1.4 0.4 14.4 18.8 16.2 15.1 0.4 1.4 13.6 12.4 4.6 15.6 12.3 15.6 12.5 12.8 5.3 4.7 10.0 15.9 11.1 5.0 7.9 26.3 16.6 16.5 21.2 9.6 0.0 13.6 14.5 0.3 0.2 13.5 5.4 2.1 7.9 13.3 12.4 21.8 8.0 11.2 25.3 13.4 11.9 13.1 13.0 19.4 24.7 8.5 2.5 7.9 12.2 11.8 8.3 7.5 4.6 7.8 14.1 9.7 5.2 23.3 23.1 13.7 26.0 7.0 6.9 15.7 7.5 10.4 15.0 1.8 0.6 0.4 0.5 0.3 0.4 0.8 0.7 0.5 0.3 1.1 0.4 0.5 2.0 1.0 0.3 0.8 1.4 0.4 0.5 0.4 0.4 0.4 0.5 0.5 0.6 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.4 0.1 0.0 0.0 1.9 0.0 0.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.6 2.5 0.4 0.7 0.5 0.6 0.1 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187715 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.7;testis: 18.2" "Cell type enhanced" "Detected in some" 23 "Erythroid cells: 46.7;Extravillous trophoblasts: 10.5;Spermatocytes: 17.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 10.0;T-reg: 3.2" "Group enriched" "Detected in many" 64 "NK-cells: 10.0;T-cells: 3.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA036909, HPA036910" Approved Enhanced "Nucleoplasm,Cytokinetic bridge,Cleavage furrow" Yes Yes "Nucleoplasm, Cleavage furrow" "Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 2.3 1.7 0.3 3.6 0.4 10.4 0.7 0.3 0.7 1.7 2.7 0.4 0.3 2.7 1.6 2.2 10.7 0.3 0.3 0.8 0.3 0.3 1.2 1.2 2.3 6.7 0.6 0.4 0.8 0.5 0.0 0.3 6.6 0.5 1.0 4.2 0.4 2.0 0.3 0.5 3.5 2.7 4.4 0.5 3.8 2.1 18.2 0.3 47.7 0.5 6.1 11.7 1.8 3.0 0.1 0.0 0.0 0.0 10.0 3.2 0.4 22.2 15.0 33.2 22.0 1.7 3.3 14.3 19.3 17.7 42.1 31.8 28.2 20.8 9.6 10.4 24.3 15.8 22.1 31.1 36.1 42.2 14.0 14.7 14.2 26.8 17.9 0.1 6.9 6.6 1.2 0.6 22.4 12.9 7.1 27.2 13.7 5.9 18.4 29.1 20.4 11.6 6.8 21.0 13.1 16.4 12.8 33.3 9.9 11.5 11.0 9.9 9.8 36.5 12.4 8.5 44.5 15.8 7.2 12.9 11.0 16.4 9.9 32.2 9.5 9.1 10.7 7.1 20.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.5 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 3.2 0.4 0.3 0.4 0.3 0.7 0.3 0.3 0.6 0.4 0.5 0.3 0.0 1.7 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.4 46.7 0.0 10.5 0.4 0.1 4.6 0.0 4.9 0.0 0.0 3.7 1.0 1.0 0.3 0.6 0.0 0.0 0.1 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 17.9 4.6 0.4 0.8 0.0 1.6 0.0 KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701610-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 26.2" "Cell type enhanced" "Detected in many" 9 "Erythroid cells: 70.0;Spermatocytes: 149.9;Spermatogonia: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Cytosol" Yes Yes "Nucleoplasm, Cytokinetic bridge" "Midbody, Cytosol" "HPA050214: AB_2681053" "unprognostic (2.13e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (7.39e-2)" "unprognostic (8.95e-5)" "unprognostic (3.32e-3)" "unprognostic (2.01e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (3.06e-6)" "unprognostic (4.22e-3)" "unprognostic (2.70e-1)" "unprognostic (2.51e-2)" "unprognostic (6.43e-2)" 3.9 2.3 1.3 5.9 6.6 11.1 3.2 12.8 3.0 4.1 3.8 0.7 1.1 4.3 3.4 2.2 7.0 3.3 1.5 2.2 2.1 1.3 2.4 3.2 2.8 9.5 1.6 2.6 4.3 2.0 2.1 3.2 4.0 3.6 2.3 5.1 1.5 3.4 2.0 2.1 4.9 5.5 3.0 3.0 8.0 3.0 10.2 2.6 26.2 2.8 3.9 9.1 2.8 3.8 13.3 4.8 8.3 3.9 2.4 8.6 1.9 36.0 7.4 10.8 9.6 2.1 3.7 9.0 14.8 13.6 15.6 16.4 9.7 16.7 14.0 4.7 7.5 5.8 18.4 12.0 8.3 21.0 16.8 8.2 14.2 12.9 8.4 0.6 24.1 11.8 1.5 1.2 15.0 15.4 5.5 10.0 7.4 13.5 16.2 13.8 6.2 14.1 4.6 11.1 5.9 7.1 9.8 21.3 6.1 4.8 4.8 3.4 6.2 10.6 4.8 5.6 8.1 12.6 7.0 7.8 10.0 10.1 13.0 23.8 4.5 12.2 18.8 9.5 21.5 7.4 8.3 2.3 3.7 5.5 3.9 6.7 11.5 7.4 5.9 1.2 13.3 8.6 8.0 0.1 2.4 3.8 4.8 8.6 1.9 1.3 6.6 12.8 3.0 2.1 1.3 1.6 2.6 3.6 2.6 3.0 15.7 46.6 7.4 15.8 11.8 7.1 2.5 6.7 7.9 0.0 9.8 9.8 3.3 5.1 8.6 7.8 5.9 70.0 4.0 30.5 12.7 3.4 43.8 3.8 17.2 12.7 1.2 8.6 11.6 9.6 7.5 16.4 5.0 9.0 5.4 6.4 2.9 5.7 8.1 2.4 9.1 6.5 15.5 149.9 96.9 12.3 4.3 26.1 13.0 2.2 KIF23 "KNSL5, MKLP-1, MKLP1" ENSG00000137807 "Kinesin family member 23" Q02241 15 69414246-69448427 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.8;testis: 20.4" "Cell type enhanced" "Detected in many" 12 "Extravillous trophoblasts: 31.4;Spermatocytes: 47.9;Spermatogonia: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "eosinophil: 7.7" "Group enriched" "Detected in many" 12 "granulocytes: 7.7;monocytes: 2.2;T-cells: 2.1" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010414, HPA045208, HPA068831" Uncertain Enhanced "Nucleoplasm,Midbody ring,Mitotic spindle" Yes Yes Nucleoplasm "Midbody ring, Mitotic spindle" "CAB010414: AB_631959, HPA045208: AB_2679254, HPA068831: AB_2686045" "unprognostic (1.29e-1)" "unprognostic (2.40e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.86e-1)" "unprognostic (7.99e-3)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.43e-3)" "unprognostic (4.25e-3)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (5.85e-3)" "unprognostic (0.00e+0)" "unprognostic (1.15e-2)" "unprognostic (2.59e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" 1.8 2.6 1.8 12.7 1.3 16.3 3.2 0.3 0.9 2.2 3.3 0.3 1.4 3.5 3.3 1.2 8.8 1.8 2.4 2.2 0.7 0.5 4.9 0.8 2.5 6.7 0.9 0.5 1.6 0.9 0.0 0.3 10.8 1.3 1.9 4.3 0.6 2.1 0.9 0.3 3.0 3.9 3.4 1.4 4.5 3.1 20.4 0.2 41.8 0.6 6.3 8.8 1.8 3.3 0.3 0.1 7.7 2.2 0.1 2.1 0.6 25.2 22.0 16.3 15.6 1.0 1.9 9.9 27.7 15.0 40.2 31.3 13.3 19.8 14.8 8.4 14.3 21.4 29.2 33.6 10.3 40.9 13.7 15.7 13.9 20.6 8.2 0.6 14.3 12.9 0.9 1.1 19.2 16.2 5.1 13.6 12.0 9.2 18.5 25.2 11.1 8.0 7.7 20.2 9.4 8.8 9.1 36.3 8.2 10.6 13.1 8.3 6.9 32.2 14.2 12.1 21.4 13.5 6.5 8.8 24.3 32.4 16.8 40.7 7.2 19.5 13.3 8.6 19.3 21.4 0.0 2.2 7.7 0.0 1.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.1 1.0 0.1 2.1 0.6 1.8 1.3 0.3 0.9 0.7 0.5 0.9 0.5 1.3 0.2 0.0 0.3 0.0 2.6 1.6 0.2 0.8 7.6 1.4 6.8 7.0 2.0 5.9 3.3 1.8 6.3 0.1 1.1 0.0 0.0 31.4 3.1 0.5 2.3 0.0 6.8 0.0 1.7 6.2 3.2 3.2 0.9 2.9 0.0 10.0 2.2 0.1 0.4 0.0 1.8 0.5 0.0 6.5 2.3 47.9 18.3 0.9 2.1 0.8 2.3 1.0 KIF2C "CT139, KNSL6, MCAK" ENSG00000142945 "Kinesin family member 2C" Q99661 1 44739818-44767767 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.9;testis: 61.4" "Group enriched" "Detected in many" 18 "Early spermatids: 430.2;Late spermatids: 1559.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 5.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006219, HPA079172" Enhanced Supported Nucleoplasm,Midbody,Centrosome Yes Yes "Nucleoplasm, Centrosome" Midbody "HPA006219: AB_2667540, HPA079172: " "unprognostic (3.29e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.77e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.07e-7)" "unprognostic (7.49e-3)" "unprognostic (3.33e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (4.27e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.33e-3)" "unprognostic (1.49e-1)" "unprognostic (1.86e-2)" "unprognostic (2.41e-1)" 1.1 0.7 0.4 8.7 0.4 12.7 0.8 0.5 0.5 1.2 2.4 0.4 0.2 2.1 1.3 1.4 4.6 0.6 0.7 0.9 0.6 0.5 0.7 0.6 1.6 6.7 0.4 0.2 0.7 0.4 0.3 0.6 2.2 0.6 0.6 3.2 0.4 1.1 0.2 0.4 2.3 2.2 1.1 0.4 3.3 1.4 61.4 0.2 39.9 0.8 4.7 12.0 0.9 1.7 1.3 1.5 0.0 0.2 3.9 5.8 1.0 29.0 11.3 25.3 20.2 1.4 2.9 17.0 21.8 15.6 44.7 39.0 19.1 21.1 33.5 10.5 10.7 30.9 13.9 25.7 14.7 40.9 21.6 11.1 39.6 20.0 15.9 0.1 29.2 18.4 0.7 1.4 31.8 15.6 4.1 14.4 23.8 31.2 28.8 28.2 11.3 30.7 17.7 24.7 14.3 14.2 24.7 38.2 21.0 7.5 10.6 17.4 12.4 29.0 20.7 18.3 19.1 11.9 22.2 8.5 16.2 32.3 17.6 38.2 15.2 15.5 48.3 10.4 28.5 31.2 0.0 0.0 0.0 1.9 0.0 0.1 1.3 3.4 2.6 0.3 0.2 0.7 0.5 0.0 3.9 0.2 1.5 5.8 1.0 0.4 0.4 0.5 0.5 0.6 0.5 0.4 0.2 0.6 0.2 0.0 0.3 0.8 0.5 1.5 1.0 0.8 0.0 0.0 2.3 1.8 2.0 1.1 1.7 0.3 430.2 0.1 0.0 23.3 0.3 20.1 0.7 0.6 0.0 0.0 7.4 0.0 0.0 4.3 1.0 1559.3 8.6 1.3 0.0 7.2 0.9 0.3 0.1 0.0 6.3 0.0 0.2 6.5 0.3 55.1 28.0 0.4 3.1 0.7 1.6 0.4 KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290090-70420832 "Predicted intracellular proteins" "DNA-binding, Motor protein" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.1;lymphoid tissue: 19.3" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 46.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "T-reg: 3.2" "Lineage enriched" "Detected in single" 5 "T-cells: 3.2" "Low cell line specificity" "Detected in many" "HPA034745, HPA034746, HPA061583" Approved Supported Nucleoplasm,Midbody Yes Yes "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (8.17e-3)" "unprognostic (2.78e-2)" "unprognostic (1.02e-2)" "unprognostic (3.46e-3)" "unprognostic (3.20e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.37e-6)" "unprognostic (2.18e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (3.79e-2)" "unprognostic (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" 0.9 0.6 0.8 3.3 1.0 11.1 0.5 0.4 3.4 1.2 4.1 0.4 0.4 3.4 0.8 0.4 7.4 1.5 2.5 2.0 0.8 1.3 0.7 0.7 1.5 5.8 0.5 0.9 0.4 0.4 0.0 1.3 2.4 0.8 0.7 5.2 0.4 1.2 0.4 0.8 2.3 3.6 1.2 0.5 4.9 2.1 7.5 1.1 19.3 0.4 0.4 7.2 1.1 2.0 0.7 0.0 0.0 0.2 0.2 3.2 0.3 22.5 15.8 23.9 11.7 1.1 2.0 9.4 17.2 9.2 23.5 20.5 17.7 13.3 13.9 10.8 8.4 18.2 13.6 25.8 9.3 26.6 15.9 13.0 15.7 19.3 12.5 0.2 17.4 10.9 0.7 0.5 19.5 11.2 2.8 14.3 10.7 19.9 30.9 22.1 14.5 15.9 8.6 24.1 24.1 16.8 17.7 32.3 13.0 5.6 8.9 15.8 13.2 28.0 11.9 7.3 12.6 9.5 6.8 9.9 15.6 20.3 16.7 20.4 8.9 15.3 20.1 8.2 19.1 23.4 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.4 1.3 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 3.2 0.3 0.8 1.0 0.4 3.4 0.8 1.3 0.5 0.9 0.8 1.1 0.0 0.3 0.0 0.2 1.5 0.0 0.4 2.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.1 0.1 46.7 0.0 10.3 1.0 0.1 0.0 0.0 4.3 0.0 1.2 1.8 0.6 0.5 0.0 0.9 0.0 0.0 1.2 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 7.2 5.8 0.3 1.5 0.5 2.1 0.3 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease mutation, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "lymphoid tissue: 54.7;testis: 35.6" "Cell type enhanced" "Detected in some" 12 "Club cells: 3.4;Extravillous trophoblasts: 9.3;Hofbauer cells: 5.6;Proximal tubular cells: 8.4;Syncytiotrophoblasts: 3.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.7 0.5 0.3 7.1 0.4 5.4 0.7 0.3 0.3 0.6 4.0 0.1 0.0 1.5 0.4 0.8 3.9 0.4 0.9 0.5 0.4 0.4 0.9 1.0 1.3 4.7 0.3 0.0 0.5 0.5 0.0 0.4 2.8 0.1 0.5 1.5 0.0 0.8 0.0 0.4 0.8 3.9 0.5 0.4 3.3 0.8 35.6 0.0 54.7 0.5 4.1 3.7 0.7 0.9 2.9 1.2 0.7 0.5 0.7 2.5 0.0 10.9 5.6 11.5 8.3 0.3 1.7 5.1 12.8 5.2 10.0 8.5 6.9 4.4 7.3 4.1 5.5 7.6 13.7 10.8 6.0 10.6 12.6 3.0 21.4 9.6 2.0 0.0 16.3 10.8 0.3 0.2 6.7 4.2 1.3 8.5 13.0 13.7 12.2 11.7 3.7 13.9 3.3 5.6 6.6 6.0 12.7 16.5 3.6 1.5 9.7 9.9 4.6 11.1 6.3 1.3 3.8 6.8 5.0 7.9 11.7 10.4 13.4 7.1 4.7 15.9 14.2 4.7 11.1 11.1 0.4 0.2 0.1 0.1 0.1 0.0 2.9 1.1 0.1 1.2 2.2 0.0 0.7 0.7 0.7 0.5 0.1 2.5 0.0 0.3 0.4 0.3 0.3 0.4 0.4 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 3.4 1.8 0.0 2.4 1.7 0.2 0.0 0.0 0.0 0.0 0.5 9.3 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin/SPAG5 binding protein" Q9Y448 15 40382721-40394246 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 26.2;lymphoid tissue: 18.4;testis: 40.1;thyroid gland: 59.8" "Group enriched" "Detected in many" 4 "Early spermatids: 321.9;Late spermatids: 423.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: AB_10797378" "unprognostic (2.35e-3)" "unprognostic (6.83e-2)" "unprognostic (3.01e-1)" "unprognostic (5.23e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-2)" "unprognostic (1.54e-3)" "unprognostic (2.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.88e-9)" "unprognostic (1.70e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-1)" "unprognostic (1.52e-2)" 5.5 4.4 6.7 5.5 6.3 7.3 9.0 8.1 7.0 3.3 4.5 4.0 8.0 5.3 3.9 7.8 6.2 3.4 2.5 4.1 6.0 5.3 4.2 7.0 4.1 8.0 4.6 7.1 3.4 3.5 6.0 4.2 7.4 6.8 4.4 6.3 2.5 6.4 5.0 7.5 4.2 4.1 5.9 4.3 4.8 6.2 40.1 4.5 18.4 59.8 6.0 9.1 3.8 3.7 5.9 11.0 10.0 26.2 5.5 5.5 4.0 31.2 14.7 29.4 19.2 6.5 10.1 15.3 21.7 16.9 44.9 39.7 31.5 13.8 12.1 11.1 14.6 35.8 36.2 31.3 20.1 40.7 21.5 15.3 35.9 33.0 19.8 6.1 19.2 18.8 5.2 11.6 22.6 22.7 11.0 25.1 30.5 25.8 21.0 37.7 15.8 16.6 15.5 18.5 26.8 22.4 17.1 22.1 14.0 15.6 13.0 28.7 19.9 18.1 20.0 4.8 18.6 20.9 13.8 12.9 21.7 22.2 22.1 30.0 18.0 29.1 21.8 13.4 25.8 17.7 4.8 10.3 10.0 4.8 14.5 4.4 5.9 3.6 4.4 11.0 5.4 3.5 3.6 5.9 5.5 26.2 7.5 5.5 4.0 6.7 6.3 8.1 7.0 6.0 5.3 4.6 7.1 6.8 4.5 8.9 0.6 0.8 3.1 1.9 7.8 4.7 2.5 9.4 5.7 0.0 7.9 14.3 3.3 9.5 321.9 1.7 1.6 46.7 8.1 35.4 6.2 3.8 1.1 5.7 18.4 4.8 2.4 3.1 7.5 423.6 8.3 7.6 3.3 8.2 3.6 7.0 8.7 0.0 6.7 4.4 7.4 0.0 2.7 83.7 18.1 1.3 17.6 3.2 3.0 2.8 KPNA2 "IPOA1, QIP2, RCH1, SRP1alpha" ENSG00000182481 "Karyopherin subunit alpha 2" P52292 17 68035519-68046842 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 103.9" "Cell type enhanced" "Detected in all" 10 "Early spermatids: 663.6;Spermatocytes: 296.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015460, HPA041270" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes 38000 Nucleoplasm Cytosol "CAB015460: AB_831493, HPA041270: AB_2677385" "unprognostic (2.78e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.83e-4)" "unprognostic (2.14e-2)" "unprognostic (1.64e-1)" "unprognostic (5.16e-3)" "prognostic unfavorable (2.12e-10)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.34e-2)" "unprognostic (7.59e-2)" "unprognostic (3.72e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (1.26e-13)" "unprognostic (3.07e-2)" "unprognostic (1.78e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (2.19e-4)" 10.6 8.3 10.2 19.5 12.0 38.6 11.9 6.1 13.2 7.4 11.5 6.6 4.3 10.1 8.3 10.4 21.1 6.3 7.9 8.9 11.6 13.2 10.9 11.8 9.1 25.5 10.3 10.3 5.3 4.7 4.5 8.4 16.4 11.4 4.6 14.5 4.0 8.2 4.7 7.2 8.7 10.2 13.2 8.5 14.8 9.7 103.9 9.0 56.6 5.9 20.3 36.8 10.0 8.3 24.6 28.1 16.4 22.6 20.3 17.7 15.0 62.2 81.9 78.2 31.3 11.6 11.3 49.7 55.0 42.7 88.9 69.4 56.3 29.2 58.5 17.4 31.7 44.3 34.5 86.4 42.9 102.4 23.5 50.9 51.8 39.6 53.7 12.2 44.5 35.7 7.0 8.1 51.1 31.5 12.5 85.5 25.0 41.1 42.3 78.8 58.1 55.5 28.7 52.8 50.8 42.5 30.7 71.4 32.0 35.0 29.2 31.1 34.6 30.9 99.8 32.3 74.7 58.1 22.4 33.3 49.3 61.0 34.7 73.9 35.1 50.2 58.4 24.0 38.3 52.9 16.4 16.1 6.6 14.1 22.6 10.9 24.6 10.3 14.4 28.1 19.7 7.9 12.3 1.2 20.3 18.9 21.4 17.7 15.0 10.2 12.0 6.1 13.2 11.6 13.2 10.3 10.3 11.4 9.0 11.9 32.3 47.6 33.0 97.4 19.1 12.6 7.6 8.1 18.2 17.4 7.9 59.0 13.3 31.3 663.6 49.2 9.8 70.0 22.3 244.0 94.4 18.1 43.8 15.3 104.7 30.2 41.1 16.0 36.5 186.9 17.8 52.4 50.6 104.6 9.7 29.4 18.3 10.5 13.8 26.9 17.8 32.3 72.6 296.7 211.0 77.3 99.4 34.5 15.8 20.4 MCM10 "CNA43, DNA43, PRO2249" ENSG00000065328 "Minichromosome maintenance 10 replication initiation factor" Q7L590 10 13161554-13211104 "Predicted intracellular proteins" "DNA damage, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 31.4" "Cell type enhanced" "Detected in many" 13 "Erythroid cells: 23.3;Extravillous trophoblasts: 17.2;Spermatogonia: 14.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045899, HPA071952" Approved Supported Nucleoplasm,Nucleoli Yes Yes "Nucleoplasm, Nucleoli" "HPA045899: AB_10960529, HPA071952: AB_2686477" "unprognostic (9.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-3)" "unprognostic (1.41e-1)" "unprognostic (6.58e-3)" "unprognostic (1.78e-8)" "unprognostic (2.42e-3)" "unprognostic (3.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.78e-4)" "unprognostic (7.81e-2)" "unprognostic (0.00e+0)" "unprognostic (8.87e-2)" "unprognostic (1.29e-1)" "unprognostic (9.73e-2)" "unprognostic (1.05e-1)" 3.0 0.5 0.3 5.6 0.3 10.8 2.1 0.3 0.5 1.4 2.6 0.4 0.3 1.8 1.1 0.6 5.9 0.2 0.7 0.7 0.3 0.3 0.6 0.9 1.4 6.0 0.3 0.6 0.7 0.3 0.3 0.4 3.6 0.5 0.6 2.9 0.4 1.1 0.3 1.5 1.3 1.8 0.9 0.7 2.9 1.1 4.3 0.3 31.4 0.9 3.3 6.9 0.9 1.8 0.5 1.0 1.5 0.4 0.8 3.4 1.5 13.7 15.5 18.4 13.9 0.6 1.1 8.0 14.4 2.2 16.2 16.9 15.1 9.8 20.7 6.5 3.6 6.0 16.1 25.8 8.5 15.0 10.8 12.3 25.8 6.9 10.0 0.0 13.2 11.7 0.2 0.3 16.4 1.5 1.3 5.2 16.8 30.4 14.2 8.8 12.3 31.3 5.7 10.9 13.2 3.8 24.8 16.3 12.8 3.7 5.0 3.7 14.0 11.6 8.3 2.2 10.0 10.4 9.1 3.2 10.3 19.4 15.5 15.5 4.4 17.1 27.2 6.6 14.6 8.0 0.2 0.3 0.2 1.1 0.1 0.2 0.5 1.6 3.4 1.0 0.4 0.4 2.8 1.5 0.8 0.4 0.2 1.6 1.5 0.3 0.3 0.3 0.5 0.3 0.3 0.3 0.6 0.5 0.3 0.0 0.0 1.5 0.2 1.4 0.0 1.2 0.0 0.0 1.2 0.0 0.0 4.1 0.0 0.4 1.1 0.1 0.0 23.3 0.2 17.2 1.0 0.2 0.0 0.0 4.3 0.0 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.0 1.9 5.9 14.0 0.4 2.9 1.0 1.8 0.0 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598223-127622436 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 69.9" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 45.7;Extravillous trophoblasts: 22.4;Spermatogonia: 27.1;Syncytiotrophoblasts: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 8600 Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 2.9 3.7 2.1 24.3 4.0 32.5 3.5 6.7 3.2 4.7 7.1 3.3 2.2 4.7 4.7 5.9 11.2 4.8 5.4 3.6 2.0 2.3 3.9 3.4 3.4 14.6 2.2 3.5 5.1 3.0 2.4 2.4 26.4 3.0 3.2 6.0 2.5 4.7 1.9 7.0 6.0 7.1 2.9 2.9 13.3 3.8 20.3 3.9 69.9 4.1 16.6 20.7 3.4 5.1 10.4 3.6 0.9 1.4 5.8 10.6 3.4 25.1 21.4 23.5 20.5 1.4 3.0 23.0 13.2 8.5 26.6 29.0 35.5 16.7 27.1 12.9 6.5 22.8 20.3 41.9 15.2 16.6 22.4 26.2 44.9 28.7 25.8 0.9 41.9 19.6 1.6 1.7 18.0 2.7 3.2 8.3 29.6 22.3 24.9 9.8 33.3 38.8 30.7 34.4 21.6 18.9 43.6 33.7 38.8 5.5 19.5 29.3 22.2 33.9 10.1 3.5 9.9 21.7 32.9 4.2 20.7 17.7 25.5 17.8 25.8 29.2 67.4 14.3 31.7 7.9 0.0 0.6 0.2 4.7 1.4 5.9 10.4 4.1 5.5 2.8 9.2 3.9 5.0 0.9 5.8 0.3 3.6 10.6 3.4 2.1 4.0 6.7 3.2 2.0 2.3 2.2 3.5 3.0 3.9 3.0 1.3 6.7 1.7 4.0 2.2 7.6 0.0 10.7 5.7 0.0 0.0 45.7 0.0 4.1 0.7 1.7 1.0 0.0 1.6 22.4 3.3 0.7 1.1 1.7 15.2 0.0 3.5 1.3 1.6 0.7 1.7 1.6 1.7 15.4 5.1 1.5 1.7 0.0 1.4 0.5 1.7 0.0 2.8 6.2 27.1 2.6 28.0 3.2 12.0 0.6 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400063-35425430 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.0;lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" 11 "Cytotrophoblasts: 115.2;monocytes: 225.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 12.1 4.9 6.1 27.5 9.0 57.0 9.1 6.7 5.7 10.4 11.5 12.3 5.0 9.5 10.8 10.8 15.8 8.7 9.4 5.2 4.4 3.4 6.8 8.0 9.3 31.1 8.8 3.7 17.9 10.8 6.2 3.6 19.3 5.8 7.2 8.3 6.5 8.9 5.1 8.8 10.3 16.7 6.0 7.8 31.2 8.4 16.4 8.8 60.6 9.0 17.7 33.0 8.7 9.6 46.8 30.9 19.0 26.0 21.3 32.9 24.0 39.3 28.6 22.6 23.0 2.2 4.5 19.9 26.3 14.0 39.4 37.5 19.0 19.7 26.1 15.3 13.4 16.3 19.7 22.6 20.9 12.6 21.0 41.5 37.2 28.7 38.0 0.8 76.8 33.7 2.4 1.9 23.5 6.4 3.6 17.4 23.9 23.0 39.0 14.9 32.5 62.5 25.6 30.1 26.9 17.0 70.8 32.1 32.8 7.7 22.9 17.5 18.6 36.2 14.5 8.1 12.4 15.2 29.4 10.3 39.8 30.2 24.7 27.1 21.7 26.8 49.1 25.8 29.1 30.3 19.0 20.7 14.5 18.4 24.1 13.1 46.8 16.1 19.4 27.1 37.0 13.1 14.8 9.9 21.3 26.0 30.9 32.9 24.0 6.1 9.0 6.7 5.7 4.4 3.4 8.8 3.7 5.8 8.8 6.0 8.2 53.6 8.0 9.4 1.5 3.4 12.7 5.3 4.5 7.0 0.0 115.2 5.0 14.8 1.9 7.5 3.8 70.0 11.1 61.5 6.2 3.3 15.0 5.1 47.1 1.6 3.4 13.5 21.1 3.6 10.0 25.5 6.8 225.4 9.2 4.5 9.4 7.0 5.6 3.7 3.2 19.4 6.4 11.2 52.2 5.5 68.8 20.8 32.2 4.7 MKI67 "MIB-, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126385 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.2;lymphoid tissue: 81.5" "Cell type enhanced" "Detected in many" 19 "Erythroid cells: 163.5;Extravillous trophoblasts: 71.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 1.4;T-reg: 1.3" "Group enriched" "Detected in many" 13 "NK-cells: 1.1;T-cells: 1.4" "Low cell line specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 1.8 1.2 0.2 9.9 0.5 25.2 1.8 0.3 0.5 1.5 5.0 0.6 0.2 3.6 0.7 1.4 13.4 0.3 1.2 1.3 0.2 0.2 1.2 1.0 1.9 8.8 0.2 0.2 0.5 0.4 0.0 0.4 2.9 0.5 0.7 5.8 0.5 2.2 0.6 0.5 3.9 6.2 1.3 0.8 6.5 3.5 2.5 0.2 81.5 0.4 5.2 10.0 1.3 3.5 0.0 0.0 0.0 0.0 1.1 1.4 0.4 48.1 24.5 25.5 18.0 1.0 2.2 7.9 18.3 13.5 17.4 15.6 20.0 20.0 36.3 5.3 12.5 11.5 29.4 26.7 13.7 26.2 38.2 12.9 31.1 18.1 12.5 0.0 43.6 16.9 0.5 0.6 17.8 18.3 4.3 17.0 16.9 14.2 34.9 17.2 19.1 26.0 13.3 10.1 12.5 11.2 19.4 33.4 4.8 6.3 13.5 8.9 9.6 25.9 9.3 4.4 8.8 7.7 9.3 15.7 9.2 18.5 13.0 49.4 15.9 12.6 44.0 7.7 20.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.4 1.0 0.0 1.1 0.0 0.0 1.3 0.4 0.2 0.5 0.3 0.5 0.2 0.2 0.2 0.2 0.5 0.2 0.0 4.8 10.7 0.5 5.7 0.0 1.2 2.5 2.7 7.9 0.0 0.0 2.7 0.0 0.4 2.5 0.0 2.7 163.5 0.0 71.7 3.4 1.4 1.1 1.0 34.1 0.0 6.4 3.7 8.0 0.5 0.3 12.7 3.3 0.0 4.8 0.0 0.1 2.9 0.4 0.0 0.0 0.0 0.4 8.8 14.6 2.6 6.5 13.4 20.7 4.1 MYBL2 "B-MYB, BMYB" ENSG00000101057 "MYB proto-oncogene like 2" P10244 20 43667019-43716496 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 35.9;bone marrow: 33.0;lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" 22 "Erythroid cells: 93.5;Extravillous trophoblasts: 28.3;Spermatogonia: 25.7" "Cancer enriched" "Detected in all" 5 "testis cancer: 295.8" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 30 "plasmacytoid DC: 35.9" "Lineage enriched" "Detected in many" 30 "dendritic cells: 35.9" "Cell line enhanced" "Detected in many" "MCF7: 103.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017114, HPA030530, HPA055416" Uncertain Supported Nucleoplasm,Cytosol Yes Yes Nucleoplasm Cytosol "CAB017114: , HPA030530: AB_2673515, HPA055416: AB_2682811" "unprognostic (9.75e-3)" "unprognostic (1.29e-2)" "unprognostic (3.20e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (2.35e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.66e-3)" "unprognostic (9.23e-3)" "unprognostic (1.78e-1)" "unprognostic (2.38e-3)" "unprognostic (1.32e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-1)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" 1.7 0.7 0.2 48.3 0.2 33.0 1.0 0.2 0.2 1.0 4.4 0.2 0.1 2.7 1.1 1.1 8.4 0.3 1.7 0.9 0.2 0.2 1.0 1.2 1.8 22.3 0.3 0.1 0.8 9.4 0.0 0.4 4.0 0.2 0.7 2.7 0.3 2.9 0.1 0.3 1.8 6.4 0.6 0.3 43.9 2.9 12.6 0.1 49.2 0.6 6.4 33.8 1.9 2.1 1.1 35.9 0.0 0.0 0.0 0.4 0.3 26.3 16.8 14.9 15.4 0.1 0.5 19.3 11.9 4.0 37.8 27.9 82.4 16.6 53.3 6.9 5.2 7.9 16.1 26.9 8.2 14.2 9.9 17.2 24.9 16.8 22.2 0.0 22.7 17.3 0.3 0.7 14.4 3.2 0.8 10.1 26.5 24.8 66.3 3.3 103.7 46.1 32.0 17.1 21.2 14.7 32.1 30.6 30.5 7.0 5.4 13.7 20.0 35.5 35.7 3.6 16.4 23.5 24.9 4.7 2.3 38.0 16.7 20.5 23.0 47.4 83.8 4.9 19.5 14.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 35.9 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.1 0.2 0.1 0.0 0.0 13.4 0.2 3.8 0.0 1.7 2.5 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.3 0.0 0.5 93.5 0.8 28.3 0.4 0.1 0.0 0.0 11.2 0.0 0.0 1.3 1.6 10.0 0.0 0.5 1.7 0.0 1.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 3.4 25.7 2.0 3.1 2.1 2.2 0.9 NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335787-96373845 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease mutation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 17.2;lymphoid tissue: 41.3;testis: 60.4" "Cell type enhanced" "Detected in many" 22 "Spermatocytes: 77.0;Spermatogonia: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "basophil: 5.6;T-reg: 8.7" "Group enriched" "Detected in many" 5 "granulocytes: 5.6;T-cells: 8.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Cytosol Yes Yes Cytosol Nucleoplasm "HPA002647: AB_1078300, HPA003008: AB_1078301" "unprognostic (5.52e-2)" "unprognostic (7.37e-2)" "unprognostic (2.93e-2)" "unprognostic (2.85e-3)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "prognostic unfavorable (9.53e-6)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-2)" "unprognostic (0.00e+0)" "unprognostic (3.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (2.30e-2)" 1.3 1.1 0.8 13.2 0.9 17.2 1.7 0.7 1.2 1.5 3.9 0.7 0.4 2.9 0.7 1.1 7.4 0.4 1.0 0.8 0.8 0.7 0.9 0.9 1.5 10.6 1.0 0.6 0.8 0.6 0.1 0.5 3.4 1.0 0.7 5.1 0.6 1.9 0.4 0.6 2.7 3.5 1.4 1.2 6.7 2.1 60.4 0.8 41.3 0.6 6.4 12.2 1.7 2.2 1.3 0.5 5.6 1.0 0.1 8.7 0.8 31.2 11.9 30.2 15.6 1.1 1.6 20.0 14.8 10.4 28.7 30.3 21.9 17.5 29.2 10.5 6.5 26.2 14.1 25.8 10.1 30.8 25.6 17.1 30.1 12.4 19.8 0.2 27.8 25.7 0.5 1.1 22.2 9.4 2.7 11.3 23.4 20.8 21.6 13.6 14.7 40.7 29.0 21.6 13.8 15.1 31.7 27.5 23.7 5.7 12.1 17.9 13.7 8.6 12.1 5.2 11.9 8.9 20.6 6.5 21.2 32.4 19.8 23.9 11.6 16.5 31.0 9.1 27.9 23.9 5.6 0.0 0.3 1.3 1.0 0.2 1.3 1.9 1.5 0.5 0.9 0.0 0.7 0.3 0.1 0.0 0.0 8.7 0.8 0.8 0.9 0.7 1.2 0.8 0.7 1.0 0.6 1.0 0.8 0.0 0.0 0.8 0.2 0.6 0.4 0.4 0.0 2.7 2.3 0.0 7.9 1.1 0.0 0.4 3.9 0.5 0.0 0.0 0.0 14.1 0.4 0.5 1.1 0.5 6.8 0.0 0.0 0.6 3.2 4.0 0.9 3.0 1.7 0.0 1.0 4.7 0.2 0.0 0.4 0.0 2.3 0.0 0.9 77.0 26.2 0.6 1.6 5.4 1.2 0.6 NCL "C23, Nsr1" ENSG00000115053 Nucleolin P19338 2 231453531-231483641 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004210, HPA023981, HPA071110" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes 600000 "Nucleoplasm, Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB004210: AB_670270, HPA023981: AB_1854688, HPA071110: " "unprognostic (1.91e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.63e-2)" "unprognostic (2.72e-3)" "prognostic unfavorable (1.41e-6)" "unprognostic (3.74e-2)" "unprognostic (4.31e-3)" "unprognostic (9.78e-2)" "unprognostic (6.70e-3)" "unprognostic (6.07e-2)" "unprognostic (1.66e-2)" "unprognostic (2.57e-2)" "unprognostic (9.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.42e-2)" 71.2 68.2 59.6 67.7 77.0 96.6 71.0 72.8 69.2 72.1 63.0 79.2 46.0 48.1 80.3 63.7 85.2 65.7 45.9 55.9 57.7 53.3 66.7 94.7 55.6 78.4 67.4 51.8 93.9 77.5 94.8 83.4 69.5 79.8 64.6 75.4 47.1 58.1 51.8 120.6 70.3 56.9 70.9 88.4 80.2 59.4 41.7 76.4 118.9 67.8 82.6 105.5 79.9 60.6 40.8 41.3 20.4 36.4 52.6 53.9 40.8 63.3 59.3 71.9 52.7 42.5 46.2 74.0 71.7 48.7 67.7 60.0 97.9 45.6 84.2 61.8 55.3 90.9 62.2 143.9 96.3 116.1 49.2 60.3 140.5 56.3 131.9 46.6 160.1 53.3 43.8 55.9 84.5 89.0 38.9 71.0 76.8 125.1 28.9 59.5 86.2 140.1 99.4 107.1 66.9 42.6 104.6 129.7 73.9 49.7 84.2 62.3 44.4 48.0 55.1 63.3 61.3 41.4 81.1 60.3 54.3 56.2 63.4 94.2 54.8 53.8 181.3 39.5 104.5 56.2 9.5 27.9 20.4 47.4 33.2 53.9 40.8 41.7 42.6 41.3 38.9 46.6 42.1 6.0 52.6 36.4 35.5 34.4 40.8 59.6 77.0 72.8 69.2 57.7 53.3 67.4 51.8 79.8 76.4 271.0 357.6 280.1 370.4 408.5 137.1 290.7 137.6 385.4 589.2 184.9 45.2 333.3 195.6 173.5 15.4 228.8 106.1 210.2 218.7 336.0 249.6 218.4 431.8 217.9 213.5 76.3 191.8 122.8 135.8 18.9 201.0 194.7 156.9 238.1 192.5 194.0 213.8 138.2 150.3 209.2 125.5 148.8 282.2 390.1 563.8 385.9 316.9 226.1 268.8 321.5 NOL7 "C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1" ENSG00000225921 "Nucleolar protein 7" Q9UMY1 6 13615327-13632739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029185 Supported Supported "Nucleoli,Mitotic chromosome,Mitochondria" Yes Yes "Nucleoli, Mitotic chromosome" Mitochondria "HPA029185: AB_10601274" "unprognostic (8.76e-2)" "unprognostic (8.94e-2)" "unprognostic (8.38e-2)" "unprognostic (1.15e-2)" "unprognostic (3.75e-1)" "unprognostic (5.77e-2)" "unprognostic (2.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.64e-5)" "unprognostic (1.26e-1)" "unprognostic (2.03e-2)" "unprognostic (8.04e-3)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "unprognostic (4.79e-2)" 35.8 40.5 45.2 41.4 42.3 44.9 36.6 26.7 38.7 30.5 36.7 25.9 29.2 37.2 35.2 36.7 38.6 33.0 36.6 53.4 39.9 38.4 56.9 58.6 28.8 36.6 41.6 30.2 42.4 42.6 54.0 40.5 45.6 36.8 39.5 32.4 23.1 42.3 35.6 59.3 30.6 46.4 36.7 47.7 45.2 34.8 32.5 40.4 34.3 49.5 36.9 36.0 43.3 56.0 50.7 45.5 38.3 38.0 28.8 49.6 30.9 29.8 15.5 14.6 21.0 11.4 13.2 29.7 27.4 14.9 25.7 24.4 29.4 12.6 38.5 54.3 16.6 31.4 18.5 22.0 20.7 25.2 21.6 36.0 33.1 15.4 49.4 24.5 49.1 26.1 12.4 21.8 23.5 14.5 13.4 16.7 21.7 51.3 10.5 22.2 19.2 27.9 54.5 19.1 17.5 26.6 30.2 20.8 59.2 25.6 9.9 37.2 23.9 16.0 38.8 35.8 19.0 24.1 17.9 25.3 23.7 22.3 24.3 48.1 24.6 47.7 47.0 13.6 29.1 35.8 16.0 30.2 38.3 31.0 35.3 36.6 50.7 45.5 38.3 35.9 41.4 49.6 37.8 14.0 28.8 38.0 45.5 46.9 30.9 45.2 42.3 26.7 38.7 39.9 38.4 41.6 30.2 36.8 40.4 86.4 58.0 93.0 81.6 80.6 62.4 203.3 63.7 148.5 80.8 54.1 21.6 114.5 104.5 133.3 133.2 97.2 61.4 70.0 226.4 127.6 86.4 80.3 87.8 56.9 100.9 46.1 35.6 46.6 45.5 19.9 76.5 83.5 96.2 155.9 59.8 89.8 148.3 72.9 74.6 135.1 46.0 64.7 96.7 142.1 122.5 79.2 129.9 82.8 73.6 94.7 NUF2 "CDCA1, CT106, NUF2R" ENSG00000143228 "NUF2, NDC80 kinetochore complex component" Q9BZD4 1 163266576-163355764 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.6;testis: 29.0" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059692, HPA076604" Supported Nucleoplasm,Kinetochore,Cytosol Yes Yes Nucleoplasm "Kinetochore, Cytosol" "HPA059692: AB_2684103, HPA076604: " "unprognostic (9.41e-2)" "unprognostic (2.61e-1)" "unprognostic (2.56e-1)" "unprognostic (5.32e-3)" "unprognostic (6.20e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.04e-5)" "prognostic unfavorable (9.16e-4)" "prognostic unfavorable (4.83e-4)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (3.70e-2)" "unprognostic (0.00e+0)" "unprognostic (9.79e-2)" "unprognostic (7.88e-2)" "unprognostic (2.69e-1)" "unprognostic (5.96e-2)" 1.3 0.9 0.8 9.8 0.9 14.1 0.6 0.5 0.9 1.4 2.5 0.6 0.9 2.3 0.6 2.1 6.1 0.5 0.7 1.5 0.8 0.6 0.7 0.6 1.9 9.9 0.8 0.6 0.7 0.4 0.3 0.4 3.6 0.7 0.6 2.9 0.8 1.3 0.0 0.5 2.2 3.2 1.0 1.4 4.4 1.6 29.0 0.3 38.6 0.5 5.1 9.2 1.5 1.8 1.4 0.6 2.6 0.2 3.0 7.7 1.0 26.3 9.2 24.5 10.2 0.7 2.5 13.3 16.7 11.8 27.2 23.9 7.0 23.3 22.7 14.0 6.7 11.3 15.5 14.9 6.3 34.5 23.7 10.7 8.9 10.6 10.0 0.0 15.3 18.4 0.3 0.6 13.7 9.7 5.1 12.3 22.3 16.7 31.5 25.7 5.1 27.9 20.6 13.3 19.4 14.2 19.0 21.4 20.1 7.7 3.6 18.3 21.1 8.9 9.7 9.2 15.9 14.9 32.1 8.7 20.3 22.8 15.2 33.6 22.6 31.8 43.3 6.7 12.6 22.4 2.6 0.2 2.5 2.4 0.1 1.0 1.2 3.6 2.4 0.5 1.4 2.5 2.1 0.9 3.0 0.2 0.6 7.7 1.0 0.8 0.9 0.5 0.9 0.8 0.6 0.8 0.6 0.7 0.3 0.0 0.3 3.7 1.8 5.3 1.0 0.8 0.0 0.0 4.5 0.0 0.0 2.7 0.0 0.7 15.8 0.1 0.8 46.7 0.2 23.9 1.8 0.4 4.6 0.2 11.3 0.0 0.0 1.8 3.7 10.7 2.3 2.5 0.0 1.0 0.9 2.5 0.2 0.0 2.1 0.0 2.0 6.5 0.5 232.2 40.5 2.0 3.3 3.8 2.2 1.4 NUSAP1 "ANKT, BM037, FLJ13421, LNP, NuSAP1, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41332694-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 38.3;lymphoid tissue: 123.4" "Cell type enhanced" "Detected in many" 19 "Erythroid cells: 350.4;Extravillous trophoblasts: 100.9;Spermatocytes: 103.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "T-reg: 16.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042904, HPA074847" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" Yes Yes Nucleoplasm "Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 3.2 12.9 0.7 20.3 1.3 38.3 3.8 0.7 0.9 2.9 5.4 1.1 4.4 5.8 1.5 2.8 16.1 0.9 2.5 2.7 0.7 0.7 2.5 4.2 5.7 16.5 0.9 0.5 4.2 3.0 0.0 0.6 9.2 0.9 1.8 6.5 0.8 3.6 5.6 4.4 6.0 6.3 2.2 1.2 7.4 4.1 8.6 0.6 123.4 0.8 9.7 19.4 2.9 5.3 2.7 3.1 6.4 1.4 1.7 16.3 3.1 37.4 12.6 41.8 19.9 2.2 3.6 13.9 30.0 17.7 33.1 32.1 17.0 19.6 19.4 16.7 11.3 26.6 36.2 32.2 14.7 31.8 34.9 15.8 49.4 31.3 16.0 0.6 31.4 22.2 1.1 1.7 17.6 13.6 6.5 19.8 30.1 27.0 66.3 25.6 10.0 38.8 21.1 21.5 38.5 15.6 41.9 44.6 21.0 11.8 11.7 30.3 20.8 41.3 24.3 8.6 15.9 36.6 23.3 12.0 25.7 32.3 29.0 52.7 24.7 47.7 62.1 13.5 47.2 44.1 6.4 1.4 4.4 0.7 0.9 0.4 2.7 3.5 2.6 3.1 2.1 0.2 1.9 0.8 1.7 1.2 2.9 16.3 3.1 0.7 1.3 0.7 0.9 0.7 0.7 0.9 0.5 0.9 0.6 0.0 1.0 6.7 5.9 34.2 0.8 0.8 22.9 0.0 4.5 0.0 0.0 10.7 3.3 2.1 20.6 0.7 1.8 350.4 0.4 100.9 8.5 4.1 6.9 3.8 30.5 0.0 2.9 9.2 13.2 8.5 0.3 16.4 3.3 6.4 3.4 1.5 1.6 0.0 1.8 3.9 0.9 0.0 4.1 103.5 65.4 21.8 16.1 13.4 10.2 4.7 PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: AB_2676885, HPA062439: AB_2684764, HPA066670: AB_2685700" "unprognostic (1.82e-1)" "unprognostic (5.88e-2)" "unprognostic (5.59e-3)" "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.23e-3)" "prognostic unfavorable (1.84e-9)" "unprognostic (3.29e-2)" "unprognostic (3.40e-1)" "unprognostic (1.73e-1)" "unprognostic (4.79e-2)" "unprognostic (2.46e-2)" "unprognostic (5.65e-2)" "unprognostic (1.27e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-2)" "unprognostic (1.42e-1)" 24.4 28.1 26.0 26.1 30.1 28.2 29.6 19.0 31.8 19.7 21.9 27.2 18.1 20.4 28.0 21.3 31.2 28.0 22.7 18.1 26.3 18.5 24.2 34.9 19.8 30.0 27.2 26.6 30.5 49.0 31.3 17.0 20.2 23.6 24.2 19.2 18.6 22.2 22.1 34.1 32.3 19.8 22.9 24.3 26.4 25.2 34.5 27.2 21.2 25.3 23.1 24.9 21.8 22.6 14.4 17.8 3.9 19.4 12.4 16.2 16.3 34.3 39.2 14.5 30.8 16.7 16.4 22.3 22.9 18.8 39.1 30.5 45.4 14.8 46.6 20.5 26.0 30.2 24.0 44.5 40.8 28.8 19.9 42.8 22.6 22.5 39.1 41.7 54.5 23.8 23.1 25.7 40.6 40.9 18.7 25.1 16.7 37.2 19.0 23.6 43.3 26.4 55.3 28.1 33.8 28.8 33.8 25.3 45.6 21.4 23.8 25.1 26.0 22.6 25.8 30.3 12.1 18.1 28.0 19.8 45.9 34.8 23.3 38.2 24.2 20.7 47.6 32.2 25.1 29.3 3.9 15.8 3.9 13.3 19.4 16.2 14.4 12.4 12.7 17.8 13.8 14.2 12.7 0.6 12.4 13.9 15.4 9.5 16.3 26.0 30.1 19.0 31.8 26.3 18.5 27.2 26.6 23.6 27.2 3.0 17.6 13.7 18.1 20.0 6.4 3.4 25.5 26.8 19.4 24.4 7.9 30.6 21.6 36.3 38.4 21.1 24.6 0.0 38.0 33.3 14.9 13.1 17.4 20.7 33.9 3.2 22.5 28.8 29.7 10.4 18.4 20.8 20.3 31.5 19.9 13.1 33.1 14.0 19.1 39.6 8.1 19.4 18.4 23.5 19.3 19.9 23.8 15.0 24.7 12.2 PIMREG "CATS, FAM64A, FLJ10156, FLJ10491, RCS1" ENSG00000129195 "PICALM interacting mitotic regulator" Q9BSJ6 17 6444415-6451469 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 27.3" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 50.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA043783, HPA049934" Uncertain Enhanced Nucleoplasm Yes Yes Nucleoplasm "HPA043783: AB_2678669, HPA049934: AB_2680959" "unprognostic (5.32e-3)" "unprognostic (1.14e-2)" "unprognostic (2.33e-1)" "unprognostic (4.37e-3)" "unprognostic (1.46e-1)" "unprognostic (1.24e-2)" "unprognostic (6.55e-3)" "unprognostic (1.23e-3)" "unprognostic (1.80e-1)" "unprognostic (5.88e-2)" "unprognostic (1.47e-3)" "unprognostic (1.50e-2)" "unprognostic (0.00e+0)" "unprognostic (8.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 1.9 4.5 1.2 1.6 1.1 3.1 2.2 1.0 0.8 1.3 4.7 0.6 0.4 4.3 1.6 1.7 6.0 0.3 2.5 1.6 0.5 0.5 0.8 0.9 2.1 1.7 0.6 0.4 1.6 0.4 0.0 1.0 0.9 1.2 0.8 6.2 0.4 1.3 0.4 0.4 3.7 4.5 2.7 1.0 9.5 1.8 1.0 0.4 27.3 0.4 3.9 3.6 2.3 2.0 0.4 0.0 0.8 0.4 3.3 1.5 1.2 12.6 17.1 50.8 22.8 0.4 1.5 3.9 14.9 9.2 24.5 16.6 10.1 5.5 0.0 6.0 12.1 12.1 9.3 25.6 6.6 13.2 19.5 10.2 0.0 10.2 12.2 0.0 0.5 15.5 0.8 0.4 10.1 3.9 2.3 7.7 11.3 3.0 7.2 15.3 9.1 2.7 0.1 22.2 10.2 11.2 22.7 20.4 8.9 4.0 1.9 11.6 16.3 12.9 13.4 12.6 6.4 6.2 1.2 3.6 19.2 15.6 11.3 24.3 2.6 9.2 0.0 7.5 6.2 29.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 0.0 0.4 0.2 0.7 0.8 3.3 0.4 0.0 1.3 1.2 1.2 1.1 1.0 0.7 0.5 0.5 0.6 0.4 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.1 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966038-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 44.5;testis: 44.3" "Group enriched" "Detected in many" 4 "Erythroid cells: 70.0;Extravillous trophoblasts: 59.0;Spermatocytes: 129.3;Spermatogonia: 60.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 18.9;T-reg: 5.8" "Group enriched" "Detected in many" 6 "granulocytes: 18.9;T-cells: 5.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 3.2 2.8 3.5 13.0 3.8 43.3 3.6 12.5 5.8 3.4 9.3 1.6 0.2 6.1 3.5 4.7 15.0 2.6 2.8 3.5 5.1 4.9 2.3 1.9 5.8 9.2 3.4 4.7 3.6 3.8 1.6 1.5 10.4 5.2 2.4 9.9 2.7 3.9 1.0 2.5 9.9 6.6 5.4 3.5 5.8 5.0 44.3 0.8 44.5 1.8 15.3 16.5 3.5 4.9 0.9 2.0 18.9 0.4 2.0 5.8 0.7 32.9 40.2 33.7 22.8 3.5 6.0 18.1 47.4 28.0 52.5 40.3 26.8 32.1 12.5 18.9 30.2 32.5 44.9 38.3 20.3 49.8 23.2 42.5 26.0 52.6 24.6 0.9 12.8 22.5 1.5 2.6 29.8 30.6 11.7 29.4 20.3 21.6 26.9 48.8 28.6 13.1 19.5 13.2 43.1 17.3 13.8 42.0 16.8 23.4 25.0 30.7 24.3 45.1 25.1 16.3 24.3 30.1 25.3 17.6 34.7 30.7 28.6 68.2 8.7 23.1 15.5 15.2 31.8 53.0 18.9 0.4 2.0 0.5 0.0 0.3 0.9 1.0 1.0 1.8 0.4 0.9 0.4 0.2 2.0 0.2 2.0 5.8 0.7 3.5 3.8 12.5 5.8 5.1 4.9 3.4 4.7 5.2 0.8 0.0 1.9 12.3 5.2 14.7 6.8 2.4 0.0 4.0 10.3 3.5 0.0 9.5 0.0 2.9 17.7 3.2 2.0 70.0 2.5 59.0 7.4 5.1 9.2 1.6 17.6 3.2 5.2 9.8 8.6 12.3 3.4 7.0 3.3 9.0 4.5 4.5 1.7 2.6 1.8 0.0 3.5 6.5 10.3 129.3 60.0 12.4 12.2 6.9 7.4 5.4 PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155499-59204705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.8" "Cell type enhanced" "Detected in many" 14 "Erythroid cells: 46.7;Extravillous trophoblasts: 19.2;Kupffer cells: 13.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "non-classical monocyte: 10.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Endoplasmic reticulum" "HPA023923: AB_1855783, HPA052376: AB_2681803" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.22e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.80e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" 3.2 1.4 2.8 13.8 4.2 14.9 2.0 0.9 2.8 3.1 4.2 2.2 0.7 6.9 2.0 2.1 10.3 1.7 2.1 1.4 3.1 2.3 1.7 1.1 3.4 9.6 3.2 1.6 1.7 1.0 0.2 0.6 4.8 2.0 1.2 5.5 1.2 2.2 0.5 1.3 2.9 4.8 3.2 5.1 7.3 2.5 2.5 2.1 40.8 1.3 7.7 11.7 2.8 3.2 1.4 3.0 2.5 10.6 0.7 2.0 0.8 27.6 13.3 21.0 6.1 0.6 4.9 8.6 17.2 10.8 17.9 14.3 16.4 18.7 17.9 17.6 12.6 14.6 10.2 16.1 17.7 39.3 24.8 10.3 19.7 14.7 11.0 0.2 20.8 8.3 1.1 1.3 19.7 26.2 4.4 20.2 15.0 10.7 19.5 19.1 21.5 20.4 3.7 8.7 13.0 22.5 16.4 31.5 11.5 4.8 7.5 9.1 12.6 14.2 5.2 7.5 10.6 14.0 8.0 13.7 36.8 43.0 18.5 30.6 12.6 24.2 18.0 8.2 11.6 35.9 1.0 2.3 2.5 0.8 5.1 0.3 1.4 0.6 1.0 3.0 0.9 0.6 0.8 2.3 0.7 10.6 1.6 2.0 0.8 2.8 4.2 0.9 2.8 3.1 2.3 3.2 1.6 2.0 2.1 0.0 1.7 7.0 1.9 1.6 2.0 0.8 0.0 0.0 2.3 0.0 0.0 1.8 0.0 0.3 0.5 1.1 0.4 46.7 0.4 19.2 1.6 1.0 2.3 0.0 6.5 1.6 4.7 3.7 13.3 0.2 0.9 5.1 1.7 6.4 2.2 0.8 0.6 0.0 2.1 0.3 2.8 0.0 2.1 3.0 5.1 1.1 1.7 2.5 4.3 1.4 RACGAP1 MgcRacGAP ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" 8 "Erythroid cells: 46.7;Extravillous trophoblasts: 40.9;Spermatocytes: 65.3;Spermatogonia: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes Nucleoplasm "CAB025859: , HPA039427: AB_2676503, HPA043912: AB_2678728" "prognostic unfavorable (1.51e-4)" "unprognostic (1.91e-1)" "unprognostic (3.74e-3)" "unprognostic (1.53e-2)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.86e-6)" "unprognostic (1.15e-3)" "unprognostic (3.07e-3)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.12e-6)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (3.13e-2)" "unprognostic (4.94e-1)" "unprognostic (6.16e-2)" "unprognostic (2.15e-1)" 3.7 2.6 4.9 10.0 11.3 21.0 4.2 6.3 7.8 4.2 10.1 4.7 1.5 6.5 3.3 1.9 17.7 2.7 4.0 2.7 4.8 4.5 5.9 2.8 5.6 13.7 7.8 5.0 2.5 2.0 3.3 1.4 8.4 5.4 2.4 11.9 2.0 4.7 2.1 3.8 8.7 7.5 7.6 5.9 5.9 6.8 29.4 6.6 40.9 2.4 8.7 17.8 6.0 6.5 6.3 2.2 16.5 3.5 8.8 14.8 4.8 44.6 40.8 32.5 20.8 6.0 7.2 27.8 47.4 22.8 49.7 34.0 40.7 34.2 24.8 21.2 25.1 24.3 30.3 32.4 22.0 53.0 47.5 20.4 31.9 40.4 13.3 2.2 33.6 26.4 3.9 4.1 33.7 26.9 14.6 16.8 22.7 23.0 38.1 46.4 31.3 27.7 16.8 23.2 25.3 27.0 26.4 39.8 18.2 13.2 22.3 27.4 23.7 38.7 24.6 13.1 17.3 47.8 15.2 15.3 32.9 29.7 21.0 34.1 20.2 49.9 29.4 16.6 23.0 19.2 16.5 2.6 3.9 5.7 3.5 4.9 6.3 6.9 7.8 2.2 3.9 4.2 5.5 0.5 8.8 1.9 1.5 14.8 4.8 4.9 11.3 6.3 7.8 4.8 4.5 7.8 5.0 5.4 6.6 6.0 5.4 8.5 2.4 11.4 1.6 1.2 2.5 2.7 3.4 5.2 3.9 6.2 16.6 1.5 9.3 1.7 1.5 46.7 1.8 40.9 4.1 2.1 2.3 1.8 11.4 1.6 0.0 6.2 11.7 11.4 1.4 8.0 1.7 3.6 2.6 1.7 1.6 0.0 3.5 1.9 0.7 12.9 2.8 65.3 40.1 11.3 7.2 4.4 4.1 1.1 RAD51AP1 PIR51 ENSG00000111247 "RAD51 associated protein 1" Q96B01 12 4538798-4560048 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.8" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 33.7;Erythroid cells: 46.7;Extravillous trophoblasts: 30.1;Hofbauer cells: 34.3;Late spermatids: 50.0;Spermatocytes: 35.8;Spermatogonia: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 9.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051499 Approved Nucleoplasm Yes Yes Nucleoplasm "HPA051499: AB_2681508" "unprognostic (1.03e-1)" "unprognostic (5.44e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (6.30e-2)" "unprognostic (5.25e-3)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.15e-2)" "unprognostic (2.26e-2)" "unprognostic (6.29e-3)" "prognostic unfavorable (1.22e-5)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.44e-15)" "unprognostic (2.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.88e-2)" "unprognostic (3.75e-2)" 3.0 2.0 1.7 9.2 3.6 15.4 2.7 4.5 2.6 1.8 5.4 1.4 3.8 5.4 1.5 3.2 7.6 1.1 2.2 1.9 1.5 1.2 1.7 1.7 2.6 8.8 2.1 1.7 1.5 1.2 0.5 1.2 4.2 1.8 1.7 7.1 1.5 2.8 1.0 1.2 3.2 6.2 1.9 2.9 5.8 2.9 9.2 2.5 29.8 1.4 4.7 8.2 2.1 3.1 4.5 9.7 0.9 3.1 1.9 1.5 0.9 13.0 4.6 16.5 8.2 1.0 2.1 19.3 17.2 7.6 19.2 25.4 12.5 12.7 17.1 2.5 3.7 9.0 8.3 11.4 5.1 29.5 13.4 9.7 21.5 8.0 8.6 0.2 19.5 10.9 0.4 0.5 11.5 11.2 2.7 7.7 11.8 13.4 19.7 12.1 4.7 15.9 7.1 40.1 12.7 5.2 16.0 19.8 6.7 5.8 6.5 5.5 6.1 12.8 10.0 4.1 17.4 4.0 11.4 3.4 13.1 13.4 14.1 18.3 3.0 3.4 32.7 4.9 14.1 10.5 0.0 0.8 0.9 0.2 3.1 0.8 4.2 0.6 1.5 0.6 4.5 0.2 0.4 0.0 1.9 2.7 9.7 1.4 0.9 1.7 3.6 4.5 2.6 1.5 1.2 2.1 1.7 1.8 2.5 0.0 0.3 7.5 1.7 4.6 3.0 1.2 2.5 0.0 5.7 0.0 3.9 6.8 0.0 2.0 33.7 0.7 1.3 46.7 2.3 30.1 2.9 1.1 1.1 1.0 34.3 0.0 2.4 1.8 4.7 50.0 1.1 6.6 0.0 10.8 2.8 2.6 1.1 0.0 1.4 1.2 4.9 0.0 1.9 35.8 29.9 2.3 3.9 3.8 7.7 0.9 RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41245611-41286251 "Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1320.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Enhanced "Nuclear membrane,Vesicles,Cytosol" Yes Yes "Nuclear membrane" "Vesicles, Cytosol" "CAB004293: AB_2176987, HPA050110: AB_2681018, HPA062034: AB_2684667" "unprognostic (1.30e-2)" "unprognostic (3.16e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.28e-3)" "unprognostic (8.09e-2)" "unprognostic (9.87e-2)" "unprognostic (5.84e-2)" "unprognostic (7.56e-2)" "unprognostic (7.07e-3)" "prognostic favorable (5.39e-4)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" 12.2 30.7 23.5 16.9 28.4 28.5 16.1 17.6 41.1 8.5 11.8 23.1 7.3 12.7 9.5 9.4 26.1 11.5 13.7 11.5 26.9 30.4 12.0 25.1 11.5 19.5 31.7 28.6 10.6 20.2 11.0 17.7 16.1 28.1 11.4 9.6 7.1 16.3 13.3 12.5 51.6 12.8 12.3 22.0 14.2 16.0 64.3 28.3 22.1 12.7 14.4 21.7 13.3 29.2 8.7 7.6 8.2 14.8 7.1 13.1 9.7 58.2 30.6 20.0 20.9 10.8 8.9 24.3 50.5 27.6 51.0 26.7 37.1 19.2 31.4 40.8 37.0 24.6 54.3 36.3 39.8 30.8 25.4 56.3 26.6 29.9 28.9 13.5 42.9 20.0 8.6 19.0 36.3 32.2 16.8 26.7 11.8 34.1 22.4 29.0 49.9 25.0 34.9 21.8 53.1 36.4 30.7 19.7 33.1 19.9 33.4 18.2 12.1 35.9 31.8 18.5 19.2 18.7 17.3 41.2 39.1 37.5 21.5 41.5 16.7 22.2 29.9 27.3 30.5 22.5 2.8 9.5 8.2 11.2 11.2 13.1 7.9 11.3 10.3 7.1 8.7 10.5 8.0 2.7 7.1 14.8 7.6 11.6 9.7 23.5 28.4 17.6 41.1 26.9 30.4 31.7 28.6 28.1 28.3 3.0 24.7 28.1 17.5 20.5 15.2 17.4 22.9 9.4 9.1 8.7 13.7 15.1 3.3 34.2 259.8 12.7 10.1 0.0 17.4 28.1 9.3 32.2 5.8 17.9 14.0 14.3 24.0 11.6 13.4 1320.8 13.8 17.1 11.8 10.0 13.9 7.8 29.0 6.5 11.3 11.2 24.4 0.0 9.0 18.0 19.2 27.0 19.8 23.8 10.9 19.2 RRM2 ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10131419 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 120.9" "Cell type enhanced" "Detected in many" 19 "Erythroid cells: 93.5;Extravillous trophoblasts: 192.1;Spermatogonia: 44.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.4" "Lineage enriched" "Detected in many" 6 "T-cells: 10.4" "Low cell line specificity" "Detected in many" HPA056994 Enhanced Supported Cytosol Yes Yes Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 4.7 2.2 0.4 32.6 0.4 29.0 4.2 0.4 0.9 3.5 9.3 0.4 0.4 5.2 2.1 1.7 21.6 0.7 5.0 3.3 0.4 0.5 2.0 3.9 5.7 16.4 0.6 0.1 0.9 2.9 0.0 0.7 5.4 0.3 1.0 10.6 0.1 2.9 0.0 0.5 2.8 11.3 3.2 0.8 19.8 5.4 8.0 0.0 120.9 0.8 22.3 33.1 3.8 5.2 1.4 0.3 0.6 0.2 1.8 10.4 2.6 29.5 17.9 25.4 17.4 2.2 4.1 25.1 48.3 24.0 34.5 37.6 29.9 14.1 27.1 6.7 15.1 35.0 14.5 41.0 24.9 42.3 60.8 15.8 52.3 17.2 26.3 0.1 38.7 25.1 1.5 0.5 42.2 3.6 5.7 27.9 21.0 21.9 80.5 42.9 22.3 42.7 20.8 20.5 30.4 21.0 32.2 55.4 18.6 17.0 22.5 25.1 20.7 39.7 28.2 4.9 11.0 15.2 6.9 9.7 26.5 38.5 19.8 67.7 52.3 41.0 55.4 18.8 32.9 38.0 0.3 0.1 0.1 3.7 0.0 0.0 1.4 2.6 2.9 0.2 0.4 0.2 1.2 0.6 1.8 0.2 0.3 10.4 2.6 0.4 0.4 0.4 0.9 0.4 0.5 0.6 0.1 0.3 0.0 3.0 1.0 2.2 1.0 9.3 0.0 1.2 2.5 5.3 1.2 0.0 0.0 5.4 1.7 0.5 3.0 0.3 2.6 93.5 0.0 192.1 3.6 1.1 5.7 1.7 40.1 0.0 0.0 5.5 5.9 5.7 0.3 3.5 0.0 0.0 7.9 0.0 0.5 0.0 0.4 1.6 0.0 0.0 0.3 5.2 44.5 1.4 40.7 7.2 13.0 2.0 SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186292 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" 27 "Cytotrophoblasts: 5.4;Extravillous trophoblasts: 33.5;Hofbauer cells: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA035501, HPA069302, HPA069857" Enhanced Enhanced Nucleoplasm,Kinetochore,Cytosol Yes Yes Nucleoplasm "Kinetochore, Cytosol" "HPA035501: AB_2732469, HPA069302: , HPA069857: AB_2686214" "unprognostic (6.87e-3)" "unprognostic (5.01e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-3)" "unprognostic (2.51e-2)" "unprognostic (4.10e-2)" "unprognostic (2.55e-6)" "unprognostic (9.49e-3)" "unprognostic (2.45e-2)" "unprognostic (3.69e-2)" "unprognostic (1.65e-4)" "unprognostic (1.52e-2)" "unprognostic (0.00e+0)" "unprognostic (2.29e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-1)" "unprognostic (1.64e-1)" 0.6 0.6 0.4 9.1 0.4 8.9 1.0 0.4 1.5 0.9 3.4 0.3 0.6 2.7 0.8 0.5 4.0 0.3 1.7 0.4 0.3 0.4 0.8 1.0 0.9 6.9 0.4 0.1 0.5 0.5 0.0 0.4 3.7 0.2 0.6 3.5 0.1 1.0 0.1 0.3 1.1 3.4 0.8 0.4 4.9 1.5 8.6 0.2 40.1 0.5 2.4 7.4 1.2 1.5 9.0 4.5 8.3 0.2 0.3 2.7 0.6 9.5 10.9 14.9 9.1 0.7 1.3 10.1 10.3 5.3 15.0 16.5 7.7 11.8 14.6 5.2 4.2 10.6 5.6 14.0 5.7 19.0 18.6 9.3 16.6 7.5 6.1 0.1 15.1 14.3 0.1 0.4 16.5 7.0 2.1 8.9 17.4 14.2 26.2 12.4 9.4 23.7 8.5 15.8 10.2 8.3 15.2 19.1 8.5 3.8 7.0 7.4 7.8 11.4 14.1 6.8 11.6 9.1 10.6 2.4 11.4 13.7 10.2 20.5 11.3 26.2 17.0 6.2 15.3 17.1 8.3 0.1 1.5 0.3 0.2 0.1 8.6 0.7 0.8 0.4 9.0 0.2 0.4 1.6 0.3 0.2 4.5 2.7 0.6 0.4 0.4 0.4 1.5 0.3 0.4 0.4 0.1 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 5.4 0.0 1.1 0.0 0.0 0.0 0.0 1.6 33.5 0.0 0.0 1.1 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46580554-46621626 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.9;lymphoid tissue: 22.9;testis: 14.1" "Cell type enhanced" "Detected in many" 11 "Extravillous trophoblasts: 24.1;Spermatocytes: 27.0;Spermatogonia: 30.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: AB_2680542" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.98e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-2)" "unprognostic (2.35e-2)" "unprognostic (2.96e-4)" "unprognostic (2.26e-3)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.47e-5)" "unprognostic (4.81e-2)" "unprognostic (2.22e-16)" "unprognostic (3.59e-2)" "unprognostic (3.86e-2)" "unprognostic (2.66e-1)" "unprognostic (2.66e-1)" 1.5 0.8 1.0 17.3 3.0 18.9 0.9 2.4 1.3 0.8 2.2 0.6 0.3 1.3 1.5 2.0 5.7 0.4 1.1 1.5 1.0 0.7 5.0 0.3 1.7 11.2 0.7 0.7 1.2 0.3 0.2 0.8 2.8 0.7 0.9 2.5 0.3 2.6 0.3 1.4 3.8 2.3 1.9 1.1 9.9 1.4 14.1 0.9 22.9 0.6 3.0 12.9 2.0 1.6 4.6 2.0 1.8 5.4 0.3 3.4 2.1 15.3 16.4 6.2 7.5 1.3 3.2 8.6 31.4 12.4 30.7 14.3 7.8 10.1 13.5 14.2 14.3 12.4 10.2 13.6 10.2 38.0 8.6 9.1 14.8 12.4 13.2 0.0 13.0 18.9 0.6 0.6 22.5 9.2 3.0 16.0 7.1 6.1 14.3 33.3 10.2 11.6 10.8 4.8 7.2 17.5 21.2 41.6 21.6 6.3 4.8 2.6 3.4 21.7 11.5 4.9 5.6 6.3 10.7 9.2 22.5 14.6 21.7 24.9 11.3 14.9 21.6 10.3 14.0 22.6 0.3 0.8 1.8 0.5 1.3 0.1 4.6 0.8 0.4 1.2 1.9 0.1 0.3 0.8 0.3 5.4 2.0 3.4 2.1 1.0 3.0 2.4 1.3 1.0 0.7 0.7 0.7 0.7 0.9 0.0 1.4 0.0 0.5 1.4 0.2 1.4 2.5 0.0 2.3 0.0 0.0 3.1 0.0 0.3 6.4 0.3 0.4 0.0 0.0 24.1 1.0 0.4 0.0 0.0 10.7 0.0 0.0 2.5 2.9 1.5 0.6 3.9 1.7 2.8 0.2 1.0 0.1 0.0 0.4 0.0 0.3 0.0 0.5 27.0 30.1 0.5 3.1 0.7 0.6 0.9 SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176602 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 41.6;testis: 12.6" "Cell type enhanced" "Detected in many" 10 "Extravillous trophoblasts: 19.6;Spermatocytes: 18.7;Spermatogonia: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "T-reg: 2.3" "Group enriched" "Detected in many" 5 "NK-cells: 1.9;T-cells: 2.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039272, HPA039356, HPA061534" Approved Supported "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Mitotic spindle, Centrosome" Cytosol "HPA039272: AB_10805359, HPA039356: AB_10805475, HPA061534: " "unprognostic (3.46e-2)" "unprognostic (7.21e-2)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (9.73e-6)" "unprognostic (2.03e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.39e-2)" "unprognostic (0.00e+0)" "unprognostic (2.24e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" 0.8 0.6 0.6 6.4 0.6 6.2 0.9 0.4 1.6 0.8 2.8 0.3 0.0 1.1 1.0 0.8 5.1 0.2 0.3 0.4 0.8 0.5 0.8 0.5 1.0 6.1 0.6 0.3 0.5 0.4 0.0 0.6 2.6 0.8 0.4 4.0 0.2 0.9 0.0 0.5 2.4 3.1 1.1 0.5 2.6 1.4 12.6 0.3 41.6 0.3 5.7 6.4 0.5 1.4 0.4 0.2 0.3 0.3 1.9 2.3 0.6 11.3 6.0 10.8 9.1 0.0 2.3 8.5 15.3 6.5 19.4 13.2 9.8 12.2 15.5 4.6 8.4 8.3 10.7 14.4 6.2 21.2 13.3 7.4 20.6 3.9 5.6 0.0 16.0 8.0 0.4 0.4 15.5 5.2 1.8 9.4 13.2 10.7 6.6 12.8 8.8 24.3 14.4 12.5 17.2 11.2 16.0 23.2 7.2 4.3 4.4 13.8 5.1 5.1 8.0 3.2 7.5 7.1 12.3 3.8 7.7 11.1 7.1 18.4 4.0 8.5 15.6 1.9 12.5 22.0 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.8 1.4 0.2 0.0 0.8 0.3 0.0 1.9 0.3 0.0 2.3 0.6 0.6 0.6 0.4 1.6 0.8 0.5 0.6 0.3 0.8 0.3 0.0 0.0 2.2 0.5 1.8 0.0 0.6 0.0 2.7 2.3 0.0 0.0 1.3 0.0 0.9 5.1 0.8 0.2 0.0 1.2 19.6 0.8 0.4 0.0 0.2 4.6 0.0 0.0 2.5 1.9 6.0 1.4 2.2 0.0 1.0 0.3 0.2 0.6 0.9 1.1 0.3 0.0 0.0 0.9 18.7 13.5 2.5 1.8 1.0 2.7 0.1 SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692800-1712555 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Spermatocytes: 268.0;Spermatogonia: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes Nucleoplasm "Nucleoli, Cytosol" "HPA019254: AB_1856951, HPA061670: AB_2684581" "unprognostic (1.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (2.29e-5)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.81e-3)" "unprognostic (9.55e-3)" "unprognostic (4.58e-2)" "unprognostic (7.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.07e-2)" 19.8 18.1 26.9 30.4 28.0 60.7 27.5 23.8 30.0 19.3 19.3 14.2 20.7 16.3 20.4 21.9 25.0 19.0 15.8 17.9 25.1 26.5 23.7 21.2 18.7 43.9 19.9 24.0 23.1 17.8 13.0 19.5 27.7 16.0 20.0 21.3 17.9 24.7 21.2 15.1 24.7 17.0 20.5 17.1 26.1 18.2 50.6 12.4 52.4 24.9 17.7 42.8 23.7 26.6 24.4 24.1 45.3 29.8 19.8 36.1 30.4 29.4 12.1 17.5 18.4 15.5 17.7 18.2 25.9 22.2 31.5 31.9 25.0 34.4 38.9 15.5 21.4 37.2 18.1 35.1 23.5 37.0 15.9 19.0 48.8 15.1 25.1 19.2 45.1 23.8 12.2 18.9 23.9 15.9 18.3 17.9 26.1 34.9 38.5 38.5 10.6 69.4 41.1 21.8 31.1 21.6 52.3 28.6 24.6 30.3 22.4 19.9 15.3 22.0 14.3 15.3 24.7 23.7 29.8 15.1 26.5 15.2 27.9 40.3 22.4 40.7 93.0 24.8 38.7 26.0 9.3 29.8 21.8 23.6 22.3 21.4 24.4 30.8 33.2 24.1 18.0 26.5 25.1 45.3 19.8 19.8 19.1 36.1 30.4 26.9 28.0 23.8 30.0 25.1 26.5 19.9 24.0 16.0 12.4 14.9 16.8 53.9 86.5 93.4 17.7 7.1 25.5 8.1 7.9 34.9 23.6 121.4 91.2 43.6 64.1 31.8 21.2 23.3 27.3 39.1 59.3 64.3 23.1 26.1 70.1 23.8 34.4 29.4 34.0 32.9 40.9 44.4 62.4 61.3 27.5 27.6 30.6 23.0 41.4 37.4 11.4 12.9 49.1 268.0 323.2 92.5 37.4 59.9 37.5 71.2 TACC3 ERIC1 ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1721490-1745176 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 54.8;bone marrow: 26.0;lymphoid tissue: 64.3;testis: 58.1" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 43.8;Late spermatids: 49.1;Spermatocytes: 69.6;Spermatogonia: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in all" "neutrophil: 54.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 3.8 2.7 1.1 39.1 1.1 26.0 3.4 2.1 1.4 1.9 4.4 1.1 0.8 4.5 1.8 2.7 8.8 1.6 3.5 2.0 1.4 1.3 2.5 2.4 4.3 20.1 1.3 0.7 1.6 1.0 0.5 1.8 5.7 1.1 1.6 4.9 1.6 3.0 1.2 2.0 2.6 7.7 2.5 1.8 15.6 3.4 58.1 0.9 64.3 1.6 7.3 27.9 3.2 3.0 4.0 10.4 54.8 19.9 3.8 17.9 16.1 25.4 21.2 32.5 18.6 1.7 3.6 18.3 28.9 15.5 33.2 22.0 23.5 30.8 32.5 12.3 15.7 38.6 17.2 34.3 21.0 33.8 14.3 18.6 27.5 17.6 21.6 1.6 37.2 23.4 1.5 1.4 20.9 12.1 7.3 25.2 26.8 24.8 25.7 31.4 20.8 49.0 53.3 35.1 21.8 27.9 34.8 23.0 13.0 18.8 38.6 25.3 15.9 17.4 11.0 8.1 25.5 21.6 21.6 14.7 19.4 23.2 17.5 43.5 18.0 23.9 52.1 11.2 36.0 27.4 24.7 19.9 17.9 5.5 9.0 6.0 4.0 12.3 7.6 10.4 3.8 17.9 9.8 54.8 3.8 5.5 3.1 17.5 16.1 1.1 1.1 2.1 1.4 1.4 1.3 1.3 0.7 1.1 0.9 0.0 7.9 16.0 0.5 1.9 1.0 2.2 0.0 0.0 4.5 8.7 7.9 3.3 0.0 2.1 43.8 2.5 2.0 23.3 0.6 16.5 2.6 1.0 4.7 4.3 35.7 4.8 1.2 4.9 20.5 49.1 2.6 21.9 0.0 12.6 3.1 1.4 1.9 3.5 2.5 1.8 3.2 6.5 1.0 69.6 47.8 1.3 3.3 15.3 5.7 1.3 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388516-40417950 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 146.3;testis: 36.8" "Group enriched" "Detected in many" 4 "Erythroid cells: 280.4;Spermatocytes: 527.8;Spermatogonia: 241.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "T-reg: 5.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.7 2.0 0.4 20.0 0.5 14.6 4.1 0.4 0.5 3.0 6.9 0.5 0.5 7.0 2.0 3.4 18.2 0.7 2.4 2.3 0.6 0.5 1.4 1.9 5.5 15.4 0.6 0.4 1.2 1.1 0.0 0.4 10.7 0.6 1.2 8.0 0.6 3.2 0.3 0.6 5.9 9.2 2.6 1.8 7.3 4.5 36.8 0.3 146.3 0.9 11.8 16.7 3.2 5.7 1.3 0.3 0.3 0.3 3.2 5.7 1.1 34.3 45.6 58.1 26.6 2.9 5.9 12.9 47.1 25.4 43.4 38.5 21.4 26.3 55.4 24.0 15.9 26.0 54.7 44.6 18.8 58.3 29.5 29.8 36.6 29.2 35.6 0.2 51.2 39.0 1.3 1.5 30.5 31.1 9.4 22.8 36.1 39.5 38.0 46.8 11.9 59.3 34.4 24.1 24.9 18.2 50.4 90.2 23.0 10.4 22.0 34.3 24.7 38.0 47.5 15.0 35.3 39.8 23.6 14.9 28.6 40.4 33.0 45.2 21.8 24.6 48.3 16.1 35.3 47.7 0.3 0.0 0.0 0.6 0.0 0.0 1.3 0.9 0.9 0.3 0.4 0.2 0.1 0.3 3.2 0.3 0.0 5.7 1.1 0.4 0.5 0.4 0.5 0.6 0.5 0.6 0.4 0.6 0.3 0.0 1.3 28.7 1.4 10.4 0.0 1.1 2.5 0.0 6.8 0.0 0.0 8.4 0.0 0.9 12.5 0.7 2.1 280.4 0.0 81.4 9.7 1.2 0.0 3.9 64.5 0.0 0.0 27.6 30.0 15.2 4.4 13.1 1.7 2.8 5.9 0.0 0.2 3.6 1.8 0.0 0.0 71.1 1.4 527.8 241.9 5.4 7.4 7.7 24.2 2.6 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2, microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 92.7" "Group enriched" "Detected in many" 5 "Erythroid cells: 70.0;Extravillous trophoblasts: 57.2;Spermatocytes: 121.8;Spermatogonia: 68.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-reg: 10.4" "Group enriched" "Detected in many" 5 "granulocytes: 4.0;NK-cells: 4.8;T-cells: 10.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.8 1.7 1.0 13.4 2.0 21.7 1.2 2.2 1.7 2.2 5.7 0.5 0.3 4.6 1.2 2.3 13.3 0.5 1.9 1.5 0.8 0.7 1.2 2.7 2.6 12.9 0.7 1.1 0.8 0.5 0.0 0.7 6.6 0.9 0.7 7.4 0.5 2.3 0.5 2.2 5.9 4.7 3.2 0.9 5.9 3.2 22.0 0.6 92.7 0.7 11.0 16.2 2.2 3.8 1.0 1.4 4.0 0.1 4.8 10.4 1.3 70.8 23.8 28.8 22.5 2.3 4.2 27.8 29.8 16.9 43.3 32.7 50.5 30.7 33.4 17.6 16.6 32.4 37.5 32.8 27.0 49.5 14.4 12.7 65.4 22.8 34.4 0.7 25.1 16.8 1.4 1.5 27.1 19.8 6.2 23.3 25.3 48.3 30.5 33.9 29.1 41.9 19.5 32.1 27.4 25.8 23.9 77.8 20.2 11.6 11.6 20.9 14.1 45.6 17.3 13.5 20.7 30.0 15.3 15.7 48.6 29.9 22.2 45.7 12.2 21.1 29.9 15.2 89.5 31.6 4.0 0.0 0.5 0.6 0.0 0.3 1.0 1.9 2.3 0.6 0.4 0.4 0.7 0.4 4.8 0.1 1.4 10.4 1.3 1.0 2.0 2.2 1.7 0.8 0.7 0.7 1.1 0.9 0.6 0.0 6.2 16.2 0.8 6.2 0.8 0.8 7.6 0.0 5.7 0.0 0.0 4.4 0.0 1.0 6.4 0.3 0.6 70.0 0.4 57.2 2.9 0.6 0.0 2.5 15.9 1.6 1.2 9.8 5.3 10.6 0.9 5.1 0.0 3.6 2.6 0.3 1.2 0.6 0.0 0.0 0.3 0.0 2.1 121.8 68.8 5.4 3.9 6.9 7.3 1.4 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 130.8" "Group enriched" "Detected in many" 5 "Erythroid cells: 397.1;Extravillous trophoblasts: 368.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Supported "Plasma membrane,Cytosol" Yes Yes "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 3.1 2.3 0.4 24.0 0.9 25.1 4.3 0.4 0.7 3.8 9.5 0.4 0.8 7.8 2.0 2.6 25.6 0.6 3.2 2.8 0.5 0.4 2.1 2.1 4.6 15.6 0.6 0.5 1.2 1.3 0.0 0.6 12.6 0.9 1.3 11.7 0.7 3.7 0.6 1.0 8.3 10.0 3.5 1.2 11.6 7.0 15.3 0.5 130.8 0.8 17.6 26.3 2.8 7.8 1.2 0.9 2.7 0.6 2.4 10.0 4.2 39.3 28.9 52.2 25.0 1.4 3.2 30.0 31.3 15.9 51.6 37.1 94.9 45.6 41.8 30.7 14.9 64.3 38.9 0.2 33.5 52.7 17.8 27.5 12.9 22.2 24.9 0.4 18.4 32.3 1.0 3.6 34.9 34.2 7.8 25.1 26.7 0.2 35.6 42.4 64.9 30.3 5.2 31.3 44.8 69.3 32.2 47.3 0.2 17.4 13.7 30.1 25.1 49.3 36.1 19.8 27.4 36.5 27.1 9.1 46.3 40.5 31.4 60.5 11.3 0.3 46.5 28.1 13.1 43.8 0.0 0.1 0.0 0.2 0.0 0.0 1.2 1.2 2.3 0.9 0.2 0.2 0.1 2.7 2.4 0.6 0.5 10.0 4.2 0.4 0.9 0.4 0.7 0.5 0.4 0.6 0.5 0.9 0.5 0.0 5.9 29.5 3.6 15.3 0.0 0.0 2.5 0.0 7.9 0.0 0.0 15.5 0.0 0.8 5.8 0.2 5.5 397.1 0.4 368.9 5.1 2.7 5.7 3.9 75.1 0.0 1.2 22.7 19.9 5.4 0.9 9.3 0.0 1.8 12.8 0.0 1.0 6.2 0.0 0.0 0.0 0.0 1.9 6.1 18.0 10.2 26.1 10.1 15.1 8.2 ZNF672 FLJ22301 ENSG00000171161 "Zinc finger protein 672" Q499Z4 1 248838210-248849517 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055779, HPA062506" Approved Enhanced Nucleoplasm Yes Yes Nucleoplasm "HPA055779: AB_2682917, HPA062506: AB_2684786" "unprognostic (1.64e-2)" "unprognostic (3.45e-2)" "unprognostic (8.96e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-1)" "unprognostic (9.54e-3)" "unprognostic (7.42e-3)" "unprognostic (1.08e-2)" "unprognostic (2.50e-1)" "unprognostic (2.40e-2)" "prognostic favorable (7.51e-4)" "unprognostic (9.03e-2)" "unprognostic (1.16e-2)" "unprognostic (1.99e-2)" "unprognostic (2.69e-1)" "unprognostic (8.35e-3)" "prognostic favorable (1.79e-5)" 11.3 12.5 11.1 16.4 13.6 15.1 12.1 18.6 15.3 10.2 13.0 17.3 15.0 13.8 12.1 10.7 15.9 11.3 13.3 20.1 11.4 10.2 14.8 27.5 13.6 16.7 14.1 7.5 12.0 14.1 20.4 14.1 16.1 12.4 18.7 11.1 15.1 24.1 14.8 46.6 13.3 16.8 11.3 11.2 16.0 12.7 12.4 14.5 28.1 21.7 21.0 17.3 14.5 10.4 14.5 20.8 9.6 13.4 10.5 8.0 10.3 10.2 11.7 9.6 10.7 5.4 3.8 18.1 9.8 5.3 6.9 7.6 6.4 10.8 11.6 10.1 6.4 5.4 10.1 5.2 7.2 4.6 16.8 2.9 17.7 10.8 8.6 7.0 7.7 13.7 4.2 6.0 9.2 6.6 5.7 6.5 8.0 21.5 9.7 4.9 7.4 13.6 7.7 11.0 11.8 19.9 25.7 9.1 9.1 7.2 8.5 14.1 12.4 8.7 13.3 8.6 6.0 7.7 15.8 5.5 9.8 5.8 6.5 19.8 29.1 10.9 6.8 9.1 13.6 8.0 7.6 13.3 9.6 8.0 13.4 6.7 10.8 5.7 7.9 20.8 14.5 6.3 5.6 8.1 10.5 12.4 11.7 6.5 10.3 11.1 13.6 18.6 15.3 11.4 10.2 14.1 7.5 12.4 14.5 3.0 17.5 21.4 22.4 11.6 21.0 16.9 7.6 5.3 4.5 15.7 11.8 28.2 18.3 16.4 6.2 12.1 18.8 0.0 9.4 16.4 10.8 20.5 28.7 14.8 15.4 9.5 17.3 5.5 15.2 8.9 5.2 14.1 11.8 12.6 16.6 19.2 12.1 17.3 5.3 13.5 30.2 6.5 9.9 22.9 13.6 12.8 59.6 13.8 15.2 19.9