Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "MS evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific NX" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific NX" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific NX" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific NX" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific NX" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific NX" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific pTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific pTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [NX]" "Tissue RNA - adrenal gland [NX]" "Tissue RNA - amygdala [NX]" "Tissue RNA - appendix [NX]" "Tissue RNA - basal ganglia [NX]" "Tissue RNA - bone marrow [NX]" "Tissue RNA - breast [NX]" "Tissue RNA - cerebellum [NX]" "Tissue RNA - cerebral cortex [NX]" "Tissue RNA - cervix, uterine [NX]" "Tissue RNA - colon [NX]" "Tissue RNA - corpus callosum [NX]" "Tissue RNA - ductus deferens [NX]" "Tissue RNA - duodenum [NX]" "Tissue RNA - endometrium 1 [NX]" "Tissue RNA - epididymis [NX]" "Tissue RNA - esophagus [NX]" "Tissue RNA - fallopian tube [NX]" "Tissue RNA - gallbladder [NX]" "Tissue RNA - heart muscle [NX]" "Tissue RNA - hippocampal formation [NX]" "Tissue RNA - hypothalamus [NX]" "Tissue RNA - kidney [NX]" "Tissue RNA - liver [NX]" "Tissue RNA - lung [NX]" "Tissue RNA - lymph node [NX]" "Tissue RNA - midbrain [NX]" "Tissue RNA - olfactory region [NX]" "Tissue RNA - ovary [NX]" "Tissue RNA - pancreas [NX]" "Tissue RNA - parathyroid gland [NX]" "Tissue RNA - pituitary gland [NX]" "Tissue RNA - placenta [NX]" "Tissue RNA - pons and medulla [NX]" "Tissue RNA - prostate [NX]" "Tissue RNA - rectum [NX]" "Tissue RNA - retina [NX]" "Tissue RNA - salivary gland [NX]" "Tissue RNA - seminal vesicle [NX]" "Tissue RNA - skeletal muscle [NX]" "Tissue RNA - skin 1 [NX]" "Tissue RNA - small intestine [NX]" "Tissue RNA - smooth muscle [NX]" "Tissue RNA - spinal cord [NX]" "Tissue RNA - spleen [NX]" "Tissue RNA - stomach 1 [NX]" "Tissue RNA - testis [NX]" "Tissue RNA - thalamus [NX]" "Tissue RNA - thymus [NX]" "Tissue RNA - thyroid gland [NX]" "Tissue RNA - tongue [NX]" "Tissue RNA - tonsil [NX]" "Tissue RNA - urinary bladder [NX]" "Tissue RNA - vagina [NX]" "Tissue RNA - B-cells [NX]" "Tissue RNA - dendritic cells [NX]" "Tissue RNA - granulocytes [NX]" "Tissue RNA - monocytes [NX]" "Tissue RNA - NK-cells [NX]" "Tissue RNA - T-cells [NX]" "Tissue RNA - total PBMC [NX]" "Cell RNA - A-431 [NX]" "Cell RNA - A549 [NX]" "Cell RNA - AF22 [NX]" "Cell RNA - AN3-CA [NX]" "Cell RNA - ASC diff [NX]" "Cell RNA - ASC TERT1 [NX]" "Cell RNA - BEWO [NX]" "Cell RNA - BJ [NX]" "Cell RNA - BJ hTERT+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ [NX]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [NX]" "Cell RNA - CACO-2 [NX]" "Cell RNA - CAPAN-2 [NX]" "Cell RNA - Daudi [NX]" "Cell RNA - EFO-21 [NX]" "Cell RNA - fHDF/TERT166 [NX]" "Cell RNA - GAMG [NX]" "Cell RNA - HaCaT [NX]" "Cell RNA - HAP1 [NX]" "Cell RNA - HBEC3-KT [NX]" "Cell RNA - HBF TERT88 [NX]" "Cell RNA - HDLM-2 [NX]" "Cell RNA - HEK 293 [NX]" "Cell RNA - HEL [NX]" "Cell RNA - HeLa [NX]" "Cell RNA - Hep G2 [NX]" "Cell RNA - HHSteC [NX]" "Cell RNA - HL-60 [NX]" "Cell RNA - HMC-1 [NX]" "Cell RNA - HSkMC [NX]" "Cell RNA - hTCEpi [NX]" "Cell RNA - hTEC/SVTERT24-B [NX]" "Cell RNA - hTERT-HME1 [NX]" "Cell RNA - hTERT-RPE1 [NX]" "Cell RNA - HUVEC TERT2 [NX]" "Cell RNA - JURKAT [NX]" "Cell RNA - K-562 [NX]" "Cell RNA - Karpas-707 [NX]" "Cell RNA - LHCN-M2 [NX]" "Cell RNA - MCF7 [NX]" "Cell RNA - MOLT-4 [NX]" "Cell RNA - NB-4 [NX]" "Cell RNA - NTERA-2 [NX]" "Cell RNA - OE19 [NX]" "Cell RNA - PC-3 [NX]" "Cell RNA - REH [NX]" "Cell RNA - RH-30 [NX]" "Cell RNA - RPMI-8226 [NX]" "Cell RNA - RPTEC TERT1 [NX]" "Cell RNA - RT4 [NX]" "Cell RNA - SCLC-21H [NX]" "Cell RNA - SH-SY5Y [NX]" "Cell RNA - SiHa [NX]" "Cell RNA - SK-BR-3 [NX]" "Cell RNA - SK-MEL-30 [NX]" "Cell RNA - SuSa [NX]" "Cell RNA - T-47d [NX]" "Cell RNA - THP-1 [NX]" "Cell RNA - TIME [NX]" "Cell RNA - U-138 MG [NX]" "Cell RNA - U-2 OS [NX]" "Cell RNA - U-2197 [NX]" "Cell RNA - U-251 MG [NX]" "Cell RNA - U-266/70 [NX]" "Cell RNA - U-266/84 [NX]" "Cell RNA - U-698 [NX]" "Cell RNA - U-87 MG [NX]" "Cell RNA - U-937 [NX]" "Cell RNA - WM-115 [NX]" "Blood RNA - basophil [NX]" "Blood RNA - classical monocyte [NX]" "Blood RNA - eosinophil [NX]" "Blood RNA - gdT-cell [NX]" "Blood RNA - intermediate monocyte [NX]" "Blood RNA - MAIT T-cell [NX]" "Blood RNA - memory B-cell [NX]" "Blood RNA - memory CD4 T-cell [NX]" "Blood RNA - memory CD8 T-cell [NX]" "Blood RNA - myeloid DC [NX]" "Blood RNA - naive B-cell [NX]" "Blood RNA - naive CD4 T-cell [NX]" "Blood RNA - naive CD8 T-cell [NX]" "Blood RNA - neutrophil [NX]" "Blood RNA - NK-cell [NX]" "Blood RNA - non-classical monocyte [NX]" "Blood RNA - plasmacytoid DC [NX]" "Blood RNA - T-reg [NX]" "Blood RNA - total PBMC [NX]" "Brain RNA - amygdala [NX]" "Brain RNA - basal ganglia [NX]" "Brain RNA - cerebellum [NX]" "Brain RNA - cerebral cortex [NX]" "Brain RNA - hippocampal formation [NX]" "Brain RNA - hypothalamus [NX]" "Brain RNA - midbrain [NX]" "Brain RNA - olfactory region [NX]" "Brain RNA - pons and medulla [NX]" "Brain RNA - thalamus [NX]" "Single Cell Type RNA - Alveolar cells type 1 [NX]" "Single Cell Type RNA - Alveolar cells type 2 [NX]" "Single Cell Type RNA - B-cells [NX]" "Single Cell Type RNA - Basal glandular cells [NX]" "Single Cell Type RNA - Basal keratinocytes [NX]" "Single Cell Type RNA - Bipolar cells [NX]" "Single Cell Type RNA - Cardiomyocytes [NX]" "Single Cell Type RNA - Cholangiocytes [NX]" "Single Cell Type RNA - Ciliated cells [NX]" "Single Cell Type RNA - Club cells [NX]" "Single Cell Type RNA - Collecting duct cells [NX]" "Single Cell Type RNA - Cone photoreceptor cells [NX]" "Single Cell Type RNA - Cytotrophoblasts [NX]" "Single Cell Type RNA - Distal tubular cells [NX]" "Single Cell Type RNA - Ductal cells [NX]" "Single Cell Type RNA - Early spermatids [NX]" "Single Cell Type RNA - Endothelial cells [NX]" "Single Cell Type RNA - Enterocytes [NX]" "Single Cell Type RNA - Erythroid cells [NX]" "Single Cell Type RNA - Exocrine glandular cells [NX]" "Single Cell Type RNA - Extravillous trophoblasts [NX]" "Single Cell Type RNA - Fibroblasts [NX]" "Single Cell Type RNA - Glandular cells [NX]" "Single Cell Type RNA - granulocytes [NX]" "Single Cell Type RNA - Hepatocytes [NX]" "Single Cell Type RNA - Hofbauer cells [NX]" "Single Cell Type RNA - Horizontal cells [NX]" "Single Cell Type RNA - Intestinal endocrine cells [NX]" "Single Cell Type RNA - Ito cells [NX]" "Single Cell Type RNA - Kupffer cells [NX]" "Single Cell Type RNA - Late spermatids [NX]" "Single Cell Type RNA - Leydig cells [NX]" "Single Cell Type RNA - Macrophages [NX]" "Single Cell Type RNA - Melanocytes [NX]" "Single Cell Type RNA - monocytes [NX]" "Single Cell Type RNA - Mucus-secreting cells [NX]" "Single Cell Type RNA - Muller glia cells [NX]" "Single Cell Type RNA - Pancreatic endocrine cells [NX]" "Single Cell Type RNA - Paneth cells [NX]" "Single Cell Type RNA - Peritubular cells [NX]" "Single Cell Type RNA - Proximal tubular cells [NX]" "Single Cell Type RNA - Rod photoreceptor cells [NX]" "Single Cell Type RNA - Sertoli cells [NX]" "Single Cell Type RNA - Smooth muscle cells [NX]" "Single Cell Type RNA - Spermatocytes [NX]" "Single Cell Type RNA - Spermatogonia [NX]" "Single Cell Type RNA - Suprabasal keratinocytes [NX]" "Single Cell Type RNA - Syncytiotrophoblasts [NX]" "Single Cell Type RNA - T-cells [NX]" "Single Cell Type RNA - Undifferentiated cells [NX]" "Single Cell Type RNA - Urothelial cells [NX]" AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 109.7" "Cell type enhanced" "Detected in all" 9 "Cone photoreceptor cells: 732.4;Rod photoreceptor cells: 621.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA No "Vesicles, Plasma membrane" Cytosol "HPA017931: AB_1844406, HPA020289: AB_1844407" "unprognostic (2.11e-3)" "unprognostic (3.18e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-3)" "unprognostic (5.06e-2)" "unprognostic (4.04e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.52e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.76e-3)" "unprognostic (1.18e-1)" 5.1 5.9 11.0 5.7 11.9 7.8 6.9 25.2 26.5 4.8 4.2 3.9 6.3 3.8 4.7 7.1 3.8 4.9 4.3 7.9 14.4 12.8 7.2 3.1 7.5 6.8 9.4 11.6 3.3 6.7 109.7 10.3 6.9 10.2 5.0 4.6 4.7 3.6 12.3 6.8 3.7 3.7 5.4 9.3 5.5 5.4 4.1 6.9 4.7 16.0 2.1 5.3 4.9 5.8 1.0 0.8 4.1 3.9 2.8 5.6 1.3 16.8 10.1 9.3 9.0 8.9 9.9 29.9 13.7 10.9 8.3 7.4 10.2 6.7 0.6 3.4 17.9 11.4 7.9 7.1 7.1 17.0 12.5 3.0 9.1 6.1 6.9 8.1 6.4 21.7 8.5 6.3 15.6 20.3 6.8 17.6 8.6 1.9 9.5 14.4 2.8 5.9 3.4 4.4 3.1 5.6 3.9 10.0 1.4 6.6 35.3 3.1 4.9 7.9 6.1 7.1 6.4 3.6 9.1 17.5 18.7 12.5 13.4 13.5 9.3 2.4 1.0 15.6 10.9 12.7 2.5 1.4 0.6 4.5 0.6 4.2 0.4 4.0 3.0 0.8 1.0 5.6 4.5 4.1 2.8 3.9 0.7 3.1 1.3 11.0 11.9 25.2 26.5 14.4 12.8 9.4 11.6 10.2 6.9 32.8 38.8 3.0 17.4 14.2 235.7 71.2 99.3 10.7 23.9 136.1 732.4 65.1 36.5 37.7 19.2 43.8 67.4 23.3 57.5 45.9 24.0 51.4 20.7 30.1 51.9 289.2 69.3 93.9 98.0 23.3 35.4 45.1 10.1 50.5 26.9 42.5 48.8 26.4 43.9 53.7 621.3 19.4 29.2 45.9 51.3 8.7 178.4 135.1 14.6 50.6 AATK "AATYK, AATYK1, KIAA0641, LMR1, LMTK1, PPP1R77" ENSG00000181409 "Apoptosis associated tyrosine kinase" Q6ZMQ8 17 81117295-81166077 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.3;intestine: 28.7" "Cell type enhanced" "Detected in many" 11 "Alveolar cells type 1: 29.8;Alveolar cells type 2: 23.6;Bipolar cells: 43.5;Horizontal cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "neutrophil: 3.6" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.6" "Group enriched" "Detected in some" 6 "CACO-2: 30.3;SH-SY5Y: 10.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009073 Enhanced Uncertain Mitochondria NA NA Mitochondria "HPA009073: AB_1078076" "unprognostic (3.47e-3)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.95e-4)" "unprognostic (1.96e-1)" "unprognostic (1.94e-1)" "unprognostic (7.29e-2)" "unprognostic (9.85e-2)" "unprognostic (6.09e-2)" "unprognostic (4.27e-2)" "unprognostic (2.88e-3)" "unprognostic (2.48e-1)" "unprognostic (4.28e-6)" "unprognostic (1.58e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (4.57e-2)" 2.8 4.7 14.3 3.2 16.6 3.7 0.9 19.0 29.0 1.2 3.3 16.5 0.0 28.7 1.0 1.1 1.7 1.2 2.7 2.3 23.6 13.9 1.2 1.2 9.7 1.5 20.1 13.6 1.0 17.9 3.6 6.4 2.6 11.0 2.4 1.1 4.1 5.6 3.6 1.1 1.9 20.3 1.3 35.3 5.9 4.5 1.3 9.8 0.0 1.3 0.0 1.0 1.3 1.1 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.2 0.3 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 30.3 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.6 1.2 1.4 1.8 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.2 0.0 0.1 0.5 0.3 0.1 1.3 2.5 0.2 0.0 0.0 2.9 10.4 0.2 0.0 1.5 0.1 0.3 0.8 1.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 14.3 16.6 19.0 22.3 23.6 13.9 20.1 13.6 11.0 9.8 29.8 23.6 0.0 0.8 0.2 43.5 2.2 2.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.1 6.9 0.0 1.6 0.1 0.4 1.0 5.8 0.0 2.0 20.6 1.7 0.6 4.1 0.0 1.4 0.6 5.0 0.0 4.5 8.3 1.3 4.5 2.5 0.8 4.1 0.0 0.8 0.5 0.2 0.3 1.9 0.7 7.2 0.1 ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713946-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Yes No Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 20.1 11.6 12.4 15.0 18.1 10.7 22.0 6.7 16.0 28.9 34.3 29.1 12.1 11.9 26.6 16.9 21.4 20.8 30.9 14.2 10.3 8.4 9.9 6.7 13.8 8.7 24.1 9.4 24.2 12.2 27.7 14.5 13.6 17.1 27.3 15.8 19.4 14.6 18.0 10.8 14.2 17.0 66.6 14.3 10.8 21.9 9.8 21.2 5.8 19.5 11.4 9.1 35.8 31.9 3.1 3.1 1.1 5.0 2.4 2.6 1.6 7.2 16.1 17.2 20.8 25.3 30.9 6.3 12.7 19.9 14.9 12.6 12.6 9.4 11.9 7.3 16.8 15.3 14.0 8.7 11.7 11.0 7.4 5.4 7.8 27.4 10.7 17.3 11.9 10.9 22.5 12.9 26.6 16.5 20.8 20.6 15.4 43.5 9.5 18.1 13.7 15.1 9.8 19.1 11.3 11.9 17.5 22.3 12.8 15.1 8.5 16.1 20.1 21.3 8.3 10.2 10.5 16.2 11.0 23.6 57.2 14.8 21.8 19.9 2.9 6.8 15.9 23.5 9.9 18.1 0.2 2.1 1.1 2.0 1.2 2.6 3.1 2.0 1.9 2.0 1.4 1.9 1.7 0.2 2.4 5.0 3.1 0.9 1.6 12.4 18.1 6.7 16.0 10.3 8.4 24.1 9.4 17.1 21.2 8.9 9.9 4.2 6.4 8.1 6.2 5.8 12.7 5.3 5.7 14.0 11.8 11.3 1.7 12.6 3.1 14.3 15.4 0.0 9.5 3.5 27.8 8.1 2.3 13.4 13.7 9.5 21.2 20.3 13.7 7.4 25.9 6.5 5.0 3.6 15.7 15.7 14.3 20.3 24.1 8.4 9.7 19.4 21.0 11.9 13.6 5.9 12.7 7.9 19.1 6.4 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099327-179229684 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Cone photoreceptor cells: 157.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 32.3;TIME: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB017106: , HPA001866: AB_1078082, HPA072754: AB_2732212" "unprognostic (3.05e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (8.40e-4)" 14.3 5.2 8.6 7.4 13.7 3.7 8.3 14.9 10.6 9.2 6.6 5.8 4.5 4.0 5.4 4.7 3.9 4.3 18.8 6.8 9.7 3.9 4.9 4.3 11.5 3.7 6.5 6.1 5.6 8.4 9.2 8.4 6.1 8.1 5.1 5.2 5.8 4.5 4.4 5.2 6.6 3.7 6.9 6.2 3.9 4.7 9.2 8.6 3.6 5.8 3.1 3.6 6.7 11.2 2.8 2.0 3.8 1.2 1.8 2.2 0.6 10.1 5.6 3.7 2.5 3.2 7.4 2.3 11.3 9.3 13.9 10.1 4.1 3.1 5.9 8.4 8.0 9.6 5.1 5.4 3.8 19.8 3.7 4.9 2.8 5.1 2.0 5.9 3.1 0.9 6.8 5.0 19.8 32.3 6.0 15.4 3.0 6.7 1.7 18.1 2.7 2.5 1.7 3.6 2.0 1.8 3.7 6.3 2.9 4.7 1.6 2.3 5.2 9.4 3.0 23.2 5.9 2.7 2.6 30.1 14.5 10.8 6.9 18.1 3.1 3.9 6.1 6.8 1.8 13.9 3.8 1.2 0.4 2.2 0.4 1.0 1.8 1.4 1.4 0.9 2.8 1.9 2.0 2.6 1.8 0.5 2.0 0.8 0.6 8.6 13.7 14.9 10.6 9.7 3.9 6.5 6.1 8.1 8.6 20.8 26.6 12.4 33.8 41.7 36.0 7.0 17.8 6.7 10.3 10.4 157.1 7.7 10.0 12.7 14.0 46.7 9.7 0.0 11.9 6.7 36.0 32.7 16.2 14.5 21.0 23.8 25.9 33.7 32.7 21.4 14.1 36.5 65.8 12.6 9.6 9.8 30.1 14.4 12.7 8.4 34.1 6.5 29.3 18.2 26.3 33.5 8.7 10.1 13.9 20.7 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157875862 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Uncertain Nucleoli,Cytosol NA NA Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: AB_2732526" "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.17e-4)" 18.9 9.2 18.0 10.0 12.7 1.6 38.7 15.3 12.2 25.2 14.4 7.4 8.4 8.9 24.8 26.8 11.0 16.6 20.5 18.8 18.7 8.6 21.7 18.9 22.5 15.1 10.4 7.9 18.5 12.3 11.3 17.0 14.2 12.3 16.8 10.5 14.3 18.1 13.6 15.6 12.8 11.5 29.2 12.3 9.2 11.8 8.8 10.9 7.5 34.0 14.6 6.9 16.1 32.5 1.4 2.4 3.8 2.6 1.9 10.0 1.6 2.1 4.3 5.0 6.5 25.4 26.5 7.0 15.4 25.6 12.4 13.2 3.4 4.8 0.0 7.1 16.6 12.0 6.0 3.6 8.3 13.3 14.7 3.1 8.7 2.5 4.9 20.1 0.6 10.4 33.2 15.8 25.3 32.3 16.2 13.4 2.4 3.2 2.4 15.5 3.8 0.1 0.2 7.5 3.0 7.8 1.4 6.7 1.8 16.0 8.1 4.4 5.5 5.9 3.4 21.1 8.2 1.8 2.3 19.3 18.8 6.2 9.2 5.8 1.6 1.2 0.1 19.3 0.5 20.2 3.8 2.6 0.2 1.1 1.7 1.2 1.4 7.8 2.5 1.8 0.8 3.1 1.5 0.8 1.9 2.3 2.4 10.0 1.6 18.0 12.7 15.3 12.2 18.7 8.6 10.4 7.9 12.3 10.9 8.9 7.0 0.8 6.8 8.8 7.5 9.2 12.7 6.7 9.1 7.0 0.0 7.0 5.0 8.4 0.5 13.5 3.1 0.0 15.5 4.4 11.6 8.9 4.7 12.1 6.5 3.2 4.1 17.2 11.6 1.1 18.7 7.7 3.3 3.6 5.2 6.1 14.7 3.5 14.9 15.3 1.5 12.9 15.5 0.5 2.5 6.6 8.8 1.0 3.5 7.6 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951667-51997078 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol NA NA Cytosol "CAB026126: , HPA063761: AB_2685115" "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 11.1 7.4 12.0 6.4 14.6 7.9 14.3 14.2 24.4 8.6 16.7 5.1 28.0 19.2 6.7 13.1 14.4 10.9 11.1 7.6 11.2 10.5 24.6 21.0 10.3 7.1 8.1 14.7 7.1 35.1 24.9 10.9 7.5 7.3 10.0 17.1 8.7 21.7 34.3 11.7 30.6 19.8 8.2 5.8 6.7 17.2 10.6 4.8 3.9 9.9 5.8 8.4 10.1 12.1 0.5 1.3 6.8 4.0 0.1 1.6 0.6 6.4 14.1 11.0 6.0 12.6 9.9 6.2 7.3 8.3 7.8 5.9 28.4 10.0 2.8 10.2 7.9 8.6 11.4 10.4 8.8 8.1 4.1 12.3 6.9 3.5 8.8 14.4 11.2 26.0 19.3 11.5 8.8 11.1 8.3 10.9 10.3 7.4 8.8 6.9 13.1 10.6 9.7 10.6 13.6 4.9 5.7 8.5 3.6 21.9 9.8 14.0 11.6 7.8 11.2 5.1 8.1 12.4 7.3 6.9 5.4 8.2 6.0 3.5 5.4 3.7 3.9 5.8 5.4 6.9 4.5 2.2 6.8 0.7 3.3 1.0 0.1 0.6 0.7 1.3 0.5 1.6 0.9 1.9 0.1 4.0 0.7 1.0 0.6 12.0 14.6 14.2 24.4 11.2 10.5 8.1 14.7 7.3 4.8 3.0 12.0 3.4 9.2 16.6 41.6 5.4 22.9 13.4 14.8 24.4 27.5 0.5 3.3 12.7 2.3 9.8 23.9 0.0 12.5 0.6 5.7 12.2 10.5 19.5 3.7 35.0 23.6 14.7 16.7 6.3 9.2 7.7 6.8 2.8 32.6 10.6 12.7 24.6 8.9 16.5 23.8 6.5 15.9 3.9 16.5 22.1 0.5 2.5 22.6 11.2 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157629005 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.2;breast: 15.3" "Cell type enhanced" "Detected in many" 12 "Enterocytes: 11.4;Leydig cells: 29.4;Paneth cells: 10.4;Undifferentiated cells: 12.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.8" "Lineage enriched" "Detected in single" 4 "T-cells: 2.8" "Group enriched" "Detected in some" 4 "ASC diff: 15.4;HDLM-2: 6.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basal ganglia: 29.2;cerebral cortex: 8.1;hippocampal formation: 21.6" "HPA007982, HPA011933" Approved "Intracellular and membrane" NA NA "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 36.2 3.7 3.9 2.7 10.3 0.7 15.3 1.6 4.4 0.9 9.4 2.7 0.0 5.5 0.7 1.0 0.8 0.8 1.8 1.0 9.2 3.1 1.1 3.3 0.8 1.2 3.7 3.1 5.1 2.4 0.5 12.0 0.7 3.5 0.9 4.4 0.0 1.5 1.0 1.3 0.7 4.4 0.8 2.8 0.8 3.4 1.1 4.0 0.0 0.9 0.5 1.0 0.6 2.9 0.6 0.0 0.0 0.0 0.0 2.8 0.4 2.0 0.0 0.0 0.2 15.4 0.5 0.3 0.4 0.4 0.1 0.5 2.3 0.2 0.0 0.2 1.2 1.0 0.0 0.1 0.0 0.3 6.8 1.0 0.0 0.0 0.5 0.0 0.0 1.2 0.2 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.3 0.0 0.0 1.4 0.1 0.7 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.3 0.3 0.0 0.3 0.0 0.8 0.2 0.0 0.2 0.8 2.4 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.5 0.0 1.0 0.6 1.8 1.2 0.0 0.5 2.8 1.1 0.0 0.0 0.0 0.0 0.0 0.4 3.9 10.3 1.6 4.4 9.2 3.1 3.7 3.1 3.5 4.0 0.0 0.6 0.0 0.9 0.6 0.0 1.2 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.2 1.1 1.0 11.4 0.0 0.2 0.3 1.2 0.8 0.0 4.7 0.1 0.0 7.5 0.0 0.0 0.4 29.4 0.0 3.3 7.2 8.4 1.0 0.4 10.4 8.5 0.7 0.0 0.0 1.0 0.0 2.0 1.3 0.2 0.0 12.1 0.4 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 21.0;RH-30: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 12.0 6.0 13.6 8.2 9.9 3.8 10.7 14.5 14.2 10.2 14.1 4.7 9.7 10.4 9.3 9.9 13.6 7.6 17.7 5.6 10.0 9.0 9.0 10.3 7.5 4.7 5.9 10.6 7.6 9.8 8.6 15.9 10.6 7.3 12.2 9.1 7.6 12.2 12.0 19.6 29.5 17.8 13.8 5.4 6.5 9.3 11.0 6.4 1.5 9.5 6.9 6.8 13.5 11.8 0.7 3.0 0.5 3.6 7.7 4.6 1.4 1.3 1.6 10.0 3.7 5.9 3.8 4.1 3.1 3.7 5.3 9.3 4.3 6.0 0.0 2.8 4.9 1.9 4.7 9.1 4.5 6.8 1.0 5.5 0.6 2.8 7.4 21.0 0.6 0.7 6.3 5.7 3.4 6.8 4.1 4.0 1.2 1.4 2.6 3.6 3.5 0.3 0.5 11.3 4.0 2.6 0.1 17.5 0.9 4.2 8.5 9.9 5.6 2.6 3.1 3.8 4.5 1.9 1.0 3.1 4.9 5.8 4.6 2.1 0.7 0.2 1.8 3.0 0.3 3.9 0.4 3.0 0.5 1.2 3.6 0.5 0.3 4.6 2.1 2.3 0.7 3.0 0.7 0.1 7.7 3.1 3.0 0.4 1.4 13.6 9.9 14.5 14.2 10.0 9.0 5.9 10.6 7.3 6.4 6.0 6.5 0.5 6.7 26.4 15.8 7.8 10.2 8.1 11.4 7.0 13.7 3.9 1.7 5.0 4.1 9.8 13.2 0.0 5.6 2.1 13.5 6.7 0.0 8.6 4.7 11.1 8.6 12.9 9.4 0.8 9.2 7.6 10.1 8.2 13.8 3.7 6.3 8.6 10.6 5.0 8.5 32.3 14.4 13.8 12.8 26.1 4.5 5.1 8.5 7.1 ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453851-38493142 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 16.4;NTERA-2: 20.3;SuSa: 12.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007398, CAB025115, HPA040384" Approved Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" No No Cytosol "Nucleoplasm, Nuclear bodies" "CAB025115: , HPA007398: AB_2667822, HPA040384: AB_2732484" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-1)" 2.8 7.4 5.5 4.6 7.9 1.1 5.5 13.2 7.5 5.2 3.4 7.2 4.5 2.8 4.7 5.1 2.5 5.6 3.3 3.9 5.9 5.4 5.3 5.4 6.9 2.2 5.9 5.4 8.3 6.1 11.3 5.1 16.0 6.5 3.9 3.6 5.0 4.6 4.2 15.9 2.4 2.8 4.6 4.7 3.1 4.0 9.1 9.1 12.8 4.8 1.7 2.2 4.2 10.3 0.3 0.3 0.5 0.2 0.5 1.6 0.3 0.8 1.4 16.4 1.4 0.6 0.4 8.8 0.3 0.5 0.3 0.7 2.3 1.1 0.1 1.2 0.3 0.5 1.0 6.3 1.0 0.9 2.4 4.1 4.2 2.5 3.5 0.8 2.9 1.6 0.7 0.9 0.5 1.8 1.0 1.1 6.2 6.9 1.4 0.3 1.3 5.1 1.9 20.3 0.8 0.7 1.7 5.5 1.0 1.0 1.9 3.8 6.7 0.4 2.5 2.2 12.2 1.3 3.9 0.9 0.5 2.7 0.4 1.4 3.9 5.4 0.9 0.6 2.5 1.1 0.5 0.1 0.1 0.4 0.2 0.6 0.2 1.0 0.5 0.0 0.3 1.6 1.5 0.3 0.5 0.2 0.3 0.7 0.3 5.5 7.9 13.2 7.0 5.9 5.4 5.9 5.4 6.5 9.1 6.0 6.7 0.5 3.6 3.5 20.7 11.6 5.1 6.7 4.5 0.0 21.6 6.7 0.0 3.2 9.1 6.1 2.9 0.0 3.3 5.8 3.1 3.2 1.1 7.5 2.2 20.6 6.9 4.9 2.1 12.6 10.9 3.2 6.8 0.0 3.2 9.6 3.8 2.5 7.4 2.8 25.5 0.0 5.6 8.1 19.0 3.4 5.1 2.5 4.7 3.3 ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 55.0" "Cell type enhanced" "Detected in many" 8 "Endothelial cells: 53.3;Enterocytes: 82.1;Ito cells: 40.5;Paneth cells: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "classical monocyte: 3.6;myeloid DC: 5.0" "Group enriched" "Detected in many" 12 "dendritic cells: 5.0;monocytes: 3.6" "Cell line enhanced" "Detected in some" "ASC diff: 18.5;ASC TERT1: 12.6;EFO-21: 16.4;HUVEC TERT2: 59.9;TIME: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" NA NA "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" 25.5 5.1 3.2 9.3 4.3 0.2 15.6 1.6 3.6 15.1 20.1 3.7 13.1 4.9 12.7 11.0 12.1 13.9 11.0 15.4 3.7 3.2 13.6 3.4 55.0 19.1 4.9 3.6 5.9 6.1 21.6 2.7 44.1 5.3 12.3 14.7 12.3 6.9 10.6 14.2 8.0 11.1 8.2 3.7 14.8 8.1 3.5 3.6 1.7 12.9 6.8 5.4 9.3 11.2 0.1 5.0 0.3 3.6 0.0 0.1 0.7 0.0 0.2 0.1 0.0 18.5 12.6 0.0 0.8 1.6 0.0 0.0 0.1 0.1 0.0 16.4 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 2.7 0.0 0.4 5.2 0.0 0.1 0.0 0.0 59.9 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 1.1 46.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.7 3.2 4.3 1.6 3.6 3.7 3.2 4.9 3.6 5.3 3.6 3.0 12.2 0.0 0.2 4.6 0.0 3.9 0.0 4.0 2.3 0.0 0.0 0.5 0.0 2.5 0.0 53.3 82.1 0.0 1.2 36.2 20.2 0.5 0.0 0.0 10.2 0.0 5.2 40.5 25.4 0.7 10.9 5.6 5.0 15.4 26.0 2.3 0.0 50.9 3.2 0.0 0.2 38.8 15.3 0.1 0.7 4.6 2.2 0.0 26.4 0.4 ADCK1 FLJ39600 ENSG00000063761 "AarF domain containing kinase 1" Q86TW2 14 77800083-77935012 "Enzymes, Predicted secreted proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051012, HPA055014" Uncertain Uncertain Nucleoplasm "Secreted - unknown location" NA NA Nucleoplasm "HPA051012: AB_2681310, HPA055014: AB_2682672" "unprognostic (6.36e-2)" "unprognostic (7.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.70e-4)" "prognostic favorable (4.11e-5)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (4.57e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.82e-6)" "unprognostic (6.30e-3)" "unprognostic (2.06e-1)" "unprognostic (9.57e-2)" "unprognostic (4.06e-1)" 7.2 11.0 11.0 7.0 15.2 7.4 6.9 6.8 20.5 5.6 10.3 19.0 7.7 11.2 7.7 10.3 7.7 7.1 9.1 11.1 12.4 10.4 8.8 10.5 6.2 6.0 13.5 9.4 6.6 9.8 11.3 11.3 7.8 15.0 8.2 10.3 13.8 10.6 8.9 13.7 8.5 8.5 10.5 10.6 9.7 7.5 5.5 11.5 10.8 9.1 7.8 7.5 6.9 5.0 4.0 8.9 1.4 7.2 3.4 5.3 3.1 3.3 5.4 3.3 10.8 8.1 4.6 4.3 3.4 5.7 3.1 3.8 3.0 8.0 7.3 5.5 6.0 5.7 6.4 17.8 5.4 2.0 4.2 5.6 1.9 3.4 4.9 8.3 2.8 4.1 5.8 10.1 1.2 3.9 3.2 4.4 6.4 7.0 4.5 4.0 16.8 3.4 5.6 6.4 12.3 6.4 5.6 0.5 5.8 4.4 8.5 7.2 4.0 6.6 9.3 4.0 5.1 13.3 6.2 3.9 2.9 2.3 5.9 3.1 4.6 5.0 4.2 4.4 4.9 3.8 1.4 4.7 1.3 5.3 7.2 3.5 1.7 2.2 3.1 8.9 4.0 2.5 4.6 0.4 3.4 2.8 7.0 3.7 3.1 11.0 15.2 6.8 20.5 12.4 10.4 13.5 9.4 15.0 11.5 0.0 3.0 0.8 1.8 0.8 5.0 4.8 0.0 1.4 1.2 0.0 19.6 6.8 3.3 3.6 1.2 1.2 2.1 0.0 4.3 3.6 2.0 1.3 1.1 5.8 8.2 7.9 1.7 1.8 5.1 0.4 1.4 5.4 0.0 1.0 3.6 3.2 3.0 0.0 1.8 3.3 8.8 0.0 1.9 1.7 9.7 1.3 4.5 1.8 4.9 0.9 ADCK2 MGC20727 ENSG00000133597 "AarF domain containing kinase 2" Q7Z695 7 140673153-140696261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036036 Approved Uncertain Centrosome,Cytosol NA NA "Centrosome, Cytosol" "HPA036036: AB_10672078" "unprognostic (2.76e-1)" "unprognostic (1.79e-1)" "unprognostic (5.72e-2)" "unprognostic (5.30e-2)" "unprognostic (4.03e-3)" "unprognostic (1.52e-1)" "unprognostic (3.05e-2)" "unprognostic (7.48e-2)" "unprognostic (2.61e-1)" "unprognostic (7.10e-3)" "unprognostic (6.81e-3)" "unprognostic (9.36e-3)" "prognostic favorable (9.75e-5)" "unprognostic (1.89e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (2.13e-1)" 12.3 10.6 15.3 11.3 16.6 8.8 13.4 15.4 27.0 12.3 15.1 26.3 13.2 8.8 10.3 11.4 18.0 20.0 10.3 10.2 16.6 18.2 12.3 12.5 12.8 15.6 19.5 13.1 14.5 22.8 21.4 12.7 19.9 18.2 14.4 13.2 10.7 16.8 14.0 12.5 25.8 13.0 10.9 24.0 13.6 13.0 7.6 13.3 20.6 25.1 9.9 16.2 13.4 18.9 8.2 12.0 3.2 5.0 5.1 7.3 2.2 16.0 11.6 2.7 12.7 10.0 11.4 16.5 8.3 10.2 8.7 5.8 10.5 11.4 21.6 12.6 5.8 20.4 13.3 13.9 9.5 2.6 15.9 14.2 4.5 4.5 5.1 13.9 3.0 11.3 9.5 29.1 5.0 6.9 9.0 7.5 15.4 7.9 10.6 3.1 20.0 22.5 7.5 4.0 12.8 12.6 17.8 0.1 10.4 4.7 16.1 10.8 7.6 11.4 16.7 11.4 5.5 14.8 6.1 7.9 10.9 3.8 18.1 16.0 7.4 11.2 15.8 16.1 12.1 12.9 0.0 3.7 3.2 5.4 5.0 4.9 8.2 4.8 5.3 5.7 4.2 7.3 4.7 0.1 5.1 3.0 12.0 6.0 2.2 15.3 16.6 15.4 27.0 16.6 18.2 19.5 13.1 18.2 13.3 8.9 5.1 8.2 18.5 11.0 11.4 5.8 5.1 2.7 1.2 8.7 0.0 25.4 5.0 5.3 16.9 9.0 8.5 0.0 6.4 18.4 7.1 15.5 11.5 8.6 27.9 11.1 16.1 6.7 7.9 12.5 3.1 11.8 3.3 7.2 13.8 11.6 5.9 14.4 12.7 4.8 4.8 0.0 6.9 5.9 3.1 12.2 28.3 7.7 11.3 16.1 ADCK5 FLJ35454 ENSG00000173137 "AarF domain containing kinase 5" Q3MIX3 8 144373101-144393242 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Enterocytes: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025692, HPA028679" Approved Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA025692: AB_10599486, HPA028679: AB_10600226" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (8.96e-2)" "unprognostic (1.68e-2)" "unprognostic (1.00e-1)" "unprognostic (2.31e-3)" "unprognostic (6.45e-2)" "unprognostic (2.70e-1)" "unprognostic (4.25e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (1.33e-3)" "unprognostic (1.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-1)" "unprognostic (2.90e-2)" 4.1 10.0 4.8 8.9 4.5 4.5 4.3 11.5 9.1 4.6 18.3 2.8 7.6 19.1 5.8 4.2 7.2 4.2 6.3 3.8 3.9 4.1 4.8 6.9 3.7 5.0 3.4 8.4 5.5 5.6 4.7 4.1 3.7 4.5 4.7 4.0 4.6 7.4 4.7 5.6 8.3 17.0 2.7 2.4 6.7 5.6 7.7 3.8 6.8 4.1 4.9 6.1 5.1 5.0 4.7 6.3 2.5 5.4 1.8 4.1 2.8 3.9 4.9 1.1 3.4 0.9 0.8 5.7 3.3 1.9 2.7 0.9 5.3 4.2 1.7 2.4 0.7 0.9 5.2 0.2 3.6 0.2 4.4 1.6 4.5 3.6 5.9 2.7 1.0 3.5 1.4 2.1 0.9 0.8 1.5 1.8 3.1 2.9 3.1 1.5 10.3 3.2 4.4 0.7 3.4 3.7 4.3 1.7 3.1 1.8 3.7 0.7 1.8 4.9 3.9 2.8 0.9 3.4 3.0 1.3 1.4 5.2 3.5 2.2 1.4 0.4 1.6 3.2 3.9 2.0 1.8 4.2 2.5 2.3 5.4 3.0 1.8 2.8 1.8 6.3 4.7 2.9 1.5 0.7 1.8 5.0 4.0 4.1 2.8 4.8 4.5 11.5 9.1 3.9 4.1 3.4 8.4 4.5 3.8 3.0 1.7 2.2 3.4 3.7 9.2 2.0 7.6 6.7 1.2 5.2 15.7 3.5 3.3 7.7 6.5 4.1 43.3 0.0 6.3 9.4 3.9 2.3 9.2 6.7 7.0 3.2 8.1 3.7 3.8 8.6 5.5 5.2 3.3 11.8 26.0 5.8 9.0 14.0 6.7 5.1 15.2 12.9 3.3 13.4 10.4 4.4 2.1 5.7 20.0 2.2 AKT1 "AKT, PKB, PRKBA, RAC" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eosinophil: 30.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 30.7" "Cell line enhanced" "Detected in all" "MCF7: 115.3" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules NA NA Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favorable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favorable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 31.7 45.4 22.9 24.2 23.6 20.3 40.0 20.9 29.5 24.7 32.6 20.0 30.8 22.5 27.0 21.5 33.0 25.5 30.3 47.7 22.9 19.1 26.3 49.2 31.3 21.0 22.1 14.7 25.9 43.0 20.3 16.7 28.4 21.5 31.1 18.2 25.3 30.4 36.1 23.8 20.4 24.0 40.5 17.5 35.4 32.6 16.2 18.8 26.3 32.7 22.4 29.3 36.7 35.9 3.2 5.2 30.7 5.8 5.7 6.2 3.0 15.4 30.8 25.5 37.9 19.7 20.5 28.5 28.4 34.6 42.0 33.7 20.2 18.7 18.7 21.9 38.9 21.4 20.1 18.0 26.4 18.3 42.6 7.3 14.1 18.4 21.7 21.9 23.0 36.9 29.3 22.3 21.0 14.0 20.2 31.4 18.4 12.3 20.8 26.9 115.3 28.9 29.4 6.6 30.3 22.1 27.3 23.6 12.7 19.4 38.4 29.3 24.3 23.7 31.0 17.8 11.9 40.6 34.3 25.0 28.2 13.5 40.1 28.5 22.6 10.9 16.1 23.8 19.5 33.9 3.3 5.3 30.7 5.4 5.2 4.0 2.9 4.8 6.2 3.6 3.2 2.5 5.7 11.8 5.7 5.8 5.2 4.7 3.0 22.9 23.6 20.9 29.5 22.9 19.1 22.1 14.7 21.5 18.8 14.9 24.3 13.4 13.8 11.0 24.3 13.8 40.8 5.3 11.4 21.0 11.8 15.1 11.6 21.0 1.2 19.6 22.2 0.0 30.3 25.7 18.8 34.2 2.3 38.4 20.2 39.7 28.8 24.5 23.7 3.1 26.4 18.1 10.1 17.2 36.1 35.8 43.4 17.3 29.0 13.9 24.0 25.8 11.8 0.9 5.1 12.2 19.6 18.1 26.9 30.8 AKT2 ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease mutation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: AB_2685278" "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 31.1 20.3 15.4 17.6 15.2 21.3 18.2 46.3 18.2 23.3 18.2 23.4 21.2 12.3 22.8 28.0 22.1 22.7 14.0 23.1 15.4 10.0 23.0 62.5 14.6 17.8 17.9 13.3 27.8 24.5 21.1 24.0 17.5 14.7 19.7 12.3 26.8 18.5 24.3 48.5 18.3 17.1 20.0 16.8 18.7 15.5 21.3 15.7 26.6 52.6 29.5 23.6 19.6 19.9 6.3 8.8 7.7 4.4 3.2 4.9 2.4 22.8 56.3 21.5 22.1 26.8 32.8 11.9 15.3 22.6 31.7 28.3 24.8 21.3 23.3 13.6 33.6 13.3 10.0 23.8 31.8 20.4 22.3 27.1 15.3 35.7 15.5 16.8 17.5 18.4 30.2 19.1 21.5 20.4 25.1 6.9 25.7 19.6 24.5 17.6 19.0 27.8 8.5 11.6 25.4 15.1 18.5 11.7 16.8 24.7 37.4 29.6 18.1 15.7 26.8 12.7 23.0 21.2 22.6 6.8 19.4 19.2 17.3 23.9 22.8 19.5 19.1 18.9 20.8 15.8 7.6 4.4 3.6 4.5 2.0 4.5 3.9 3.6 3.0 3.0 6.3 3.5 4.9 7.7 3.2 2.6 8.8 2.7 2.4 15.4 15.2 46.3 18.2 15.4 10.0 17.9 13.3 14.7 15.7 14.9 12.8 36.4 20.9 21.2 67.1 26.8 28.1 12.0 10.3 57.6 39.3 25.4 18.3 18.1 2.9 17.0 18.8 0.0 26.0 20.6 22.1 24.5 13.9 74.6 19.3 57.2 18.5 12.9 19.7 7.4 39.7 13.5 21.9 19.8 19.0 52.5 20.4 19.2 25.1 18.3 109.8 19.4 23.3 11.6 16.2 24.0 32.4 17.1 20.1 24.4 AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 71.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported Cytosol NA NA Cytosol "CAB013090: AB_2533692, HPA026441: AB_1844711" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (3.77e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-1)" "unprognostic (5.47e-3)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (8.14e-2)" "prognostic unfavorable (9.27e-4)" 15.4 17.0 16.0 7.8 15.2 2.2 11.0 39.9 33.4 16.9 16.1 12.4 17.4 4.1 19.7 12.3 10.0 11.8 12.1 9.8 15.5 13.6 12.8 4.0 11.3 7.9 14.2 15.8 29.8 4.4 15.1 14.6 17.0 18.4 19.4 6.6 8.9 4.1 23.9 4.8 4.7 8.1 20.4 12.1 9.9 8.7 10.4 14.8 2.9 17.7 5.0 6.2 17.2 18.6 1.9 0.8 1.2 0.9 3.8 3.6 0.6 23.6 2.4 15.0 0.0 11.1 12.7 8.0 13.3 12.3 8.7 7.7 0.1 9.7 0.0 0.0 17.0 7.5 0.3 8.3 5.3 11.5 6.0 6.5 0.3 0.0 0.0 5.8 0.1 2.6 6.6 0.0 10.8 9.8 18.9 17.7 3.9 0.0 0.1 3.9 0.0 5.1 1.1 6.4 0.0 3.7 2.7 9.1 0.1 2.9 0.9 19.3 25.4 0.1 0.0 24.0 9.1 0.0 8.1 13.9 15.5 11.9 0.1 11.1 1.3 0.4 2.8 11.3 1.3 12.9 1.2 0.9 0.5 2.3 0.3 3.6 1.0 2.2 2.5 0.8 1.9 1.9 1.7 0.2 3.8 0.7 0.6 0.7 0.6 16.0 15.2 39.9 22.9 15.5 13.6 14.2 15.8 18.4 14.8 3.0 2.1 8.6 11.6 2.2 41.5 5.5 5.1 0.0 4.5 26.2 31.4 9.5 0.0 10.4 71.8 31.5 0.0 0.0 1.5 6.5 7.3 18.3 4.7 0.2 2.7 39.7 0.0 44.8 8.8 51.9 25.3 9.5 6.8 10.0 0.0 20.1 1.0 0.0 33.2 4.4 33.7 19.4 22.9 12.2 11.5 1.5 10.4 13.8 0.0 7.2 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921566 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.1;pituitary gland: 17.9" "Group enriched" "Detected in some" 12 "Early spermatids: 36.6;Late spermatids: 30.9" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 27.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 1.8 3.1 3.6 1.2 4.4 0.3 1.1 0.5 8.1 0.7 2.1 2.0 0.0 0.7 0.5 0.5 0.6 0.5 1.2 0.4 3.4 4.9 0.4 0.5 1.1 0.5 2.7 4.2 0.6 0.4 0.4 17.9 0.5 5.5 0.5 1.2 2.4 0.9 0.8 0.3 0.9 1.5 0.9 2.1 0.5 0.8 4.9 0.9 0.0 1.6 0.0 0.3 0.6 1.2 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 3.6 0.0 0.0 0.1 0.3 27.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 4.1 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.6 4.4 0.5 5.9 3.4 4.9 2.7 4.2 5.5 0.9 0.0 0.0 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 30.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 ALPK1 "FLJ22670, KIAA1527, Lak" ENSG00000073331 "Alpha kinase 1" Q96QP1 4 112285509-112442620 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA027435, HPA027443" Approved Approved Centrosome NA NA Centrosome "HPA027435: AB_10599614, HPA027443: AB_10599421" "unprognostic (6.24e-2)" "unprognostic (1.92e-1)" "unprognostic (9.30e-2)" "unprognostic (1.69e-2)" "unprognostic (7.40e-2)" "unprognostic (5.45e-2)" "unprognostic (2.55e-2)" "unprognostic (7.47e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (7.14e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (5.82e-7)" "unprognostic (1.60e-1)" "unprognostic (4.17e-2)" "unprognostic (2.81e-1)" "prognostic favorable (1.17e-4)" 15.1 10.6 5.3 8.3 7.7 17.3 9.3 1.3 5.9 10.8 9.5 5.8 3.0 4.5 9.8 9.2 8.8 9.2 7.5 6.1 6.1 2.3 10.8 13.4 13.2 11.4 9.7 1.0 17.4 9.7 11.0 14.0 11.5 6.6 14.0 7.8 9.6 10.4 6.8 5.0 11.8 12.1 11.3 16.6 16.2 7.4 4.2 8.5 13.7 12.4 4.7 13.7 13.6 11.6 0.9 3.2 16.3 4.3 0.4 0.8 1.2 1.6 5.0 1.6 0.3 6.6 10.6 2.0 1.9 3.5 2.6 3.3 0.5 7.7 5.1 3.3 3.3 5.3 1.1 1.7 3.0 3.9 6.5 1.7 3.6 2.0 0.4 10.6 2.2 2.2 13.1 8.6 3.8 7.9 5.9 1.0 2.7 0.9 8.9 5.0 3.1 1.3 2.0 0.4 3.7 1.3 0.6 1.1 1.6 3.9 1.9 0.5 0.8 1.8 6.6 2.9 0.3 3.0 4.1 1.9 2.4 2.1 3.7 1.3 2.3 0.7 4.4 5.7 4.6 2.1 1.3 3.2 1.4 0.2 4.3 0.6 0.8 0.6 0.1 3.2 0.9 0.8 0.6 16.3 0.4 1.9 0.5 0.0 1.2 5.3 7.7 1.3 5.9 6.1 2.3 9.7 1.0 6.6 8.5 11.9 20.3 0.9 9.4 2.6 0.2 3.1 0.0 20.1 13.6 5.2 0.0 4.0 0.0 5.6 7.5 5.5 7.0 0.0 5.8 2.6 4.1 7.1 5.8 5.8 8.7 0.0 1.2 5.5 14.8 1.6 3.4 14.0 6.8 10.0 8.5 11.3 6.3 8.6 7.1 4.0 0.2 6.5 5.1 0.7 0.5 4.0 6.1 2.2 5.7 10.3 ALPK2 HAK ENSG00000198796 "Alpha kinase 2" Q86TB3 18 58481247-58628957 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 35.3;skeletal muscle: 35.3;tongue: 12.4" "Cell type enhanced" "Detected in some" 19 "Cardiomyocytes: 79.2;Cone photoreceptor cells: 45.2;monocytes: 31.5" "Cancer enriched" "Detected in some" 6 "renal cancer: 7.3" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "non-classical monocyte: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 26.6;BJ hTERT+: 16.2;fHDF/TERT166: 24.0;U-138 MG: 13.5" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Not detected" "Not detected" "HPA027377, HPA027976, HPA028084, HPA029801" Uncertain Approved Cytosol NA NA Cytosol "HPA027377: AB_10600635, HPA027976: AB_10611246, HPA028084: AB_10601996, HPA029801: AB_10602006" "unprognostic (7.35e-2)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.60e-3)" "unprognostic (2.64e-1)" "unprognostic (8.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (1.06e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (5.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (3.20e-2)" 0.8 0.0 0.1 2.8 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.9 0.8 0.0 0.4 35.3 0.1 0.0 5.2 2.8 0.1 3.3 0.1 0.1 0.1 0.1 0.0 0.1 0.5 0.1 0.1 0.0 0.2 0.4 0.1 35.3 0.3 0.6 0.1 0.1 0.2 1.2 0.6 0.1 5.5 0.3 12.4 7.9 0.5 0.1 0.0 0.5 0.0 1.8 0.0 0.3 0.0 0.0 7.0 0.5 0.0 0.2 1.8 0.1 26.6 16.2 11.2 9.7 1.7 0.0 0.0 2.8 24.0 1.5 0.0 0.0 0.0 11.5 5.8 0.0 0.0 2.2 0.9 1.5 0.0 0.0 1.6 0.0 3.4 0.1 0.3 0.0 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.9 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 13.5 6.0 1.8 4.5 10.9 9.4 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.5 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 79.2 0.0 0.0 0.0 0.0 45.2 0.0 1.7 0.4 14.2 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.0 2.4 0.5 1.6 0.0 0.6 0.0 15.3 0.3 0.9 0.0 31.5 0.0 2.9 0.3 0.2 0.0 9.8 0.5 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 ALPK3 "KIAA1330, MAK, Midori" ENSG00000136383 "Alpha kinase 3" Q96L96 15 84816680-84873482 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.4;skeletal muscle: 47.6" "Cell type enhanced" "Detected in many" 13 "Cardiomyocytes: 52.4;Cholangiocytes: 20.4;Exocrine glandular cells: 17.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 9.5;HDLM-2: 7.1;HUVEC TERT2: 10.2;LHCN-M2: 13.9;NTERA-2: 8.5;RH-30: 25.0;THP-1: 6.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA026558 Uncertain Approved Nucleoplasm NA NA Nucleoplasm "HPA026558: AB_1844774" "unprognostic (2.69e-2)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" "unprognostic (4.61e-2)" "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.44e-3)" "unprognostic (1.42e-1)" "unprognostic (1.68e-2)" "unprognostic (1.82e-1)" "unprognostic (1.74e-3)" "unprognostic (1.23e-1)" "prognostic favorable (3.95e-7)" "unprognostic (1.76e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (4.87e-2)" 3.7 1.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.5 1.4 0.0 0.1 1.7 0.8 0.2 0.3 18.4 0.0 0.6 1.6 1.3 1.0 0.0 0.1 0.0 2.1 8.8 6.9 0.6 0.4 0.0 0.4 0.2 47.6 0.0 0.2 0.8 0.0 0.0 1.2 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.1 0.1 0.1 0.2 0.0 9.5 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 7.1 1.1 1.1 0.2 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.1 10.2 0.0 0.0 0.0 13.9 0.5 0.0 0.1 8.5 0.2 0.0 0.0 25.0 0.1 0.0 2.6 0.0 0.1 0.0 1.3 0.0 1.3 0.0 6.1 0.2 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.5 0.0 0.8 3.1 52.4 20.4 0.0 1.2 8.7 15.7 0.2 0.0 3.1 0.1 4.5 0.0 0.0 17.3 0.6 1.5 0.5 1.1 1.5 7.9 0.0 8.7 2.5 0.3 0.0 0.0 1.9 3.3 8.2 0.3 0.9 13.6 0.2 0.0 1.7 3.0 0.0 8.3 0.2 3.1 0.1 0.6 0.0 0.3 0.8 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 27.1;ovary: 38.2;testis: 15.2" "Group enriched" "Detected in some" 4 "granulocytes: 25.4;Ito cells: 12.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "HEL: 28.3;K-562: 15.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "hippocampal formation: 14.3" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA Vesicles "Nucleoplasm, Cytosol" "HPA060228: AB_2684227, HPA069636: AB_2686163" "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.3 27.1 0.2 0.2 0.4 0.0 0.2 0.2 0.2 0.2 0.3 0.3 0.2 0.0 0.3 0.6 0.4 0.2 0.4 0.8 0.2 0.0 0.2 1.1 0.3 0.2 0.2 0.2 38.2 8.8 0.1 0.2 0.2 0.3 0.4 0.0 0.2 0.2 0.2 2.5 0.0 0.4 0.5 0.2 3.7 0.3 15.2 0.2 0.2 0.2 0.5 0.3 0.3 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 28.3 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.2 0.4 0.2 0.2 0.2 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 2.4 0.0 0.0 0.0 1.8 0.0 0.0 0.1 25.4 0.0 0.1 0.0 0.0 12.3 2.2 1.3 4.6 0.0 0.0 0.0 0.0 0.0 4.6 0.0 3.9 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.2 0.0 0.0 0.0 ANKK1 X-kinase ENSG00000170209 "Ankyrin repeat and kinase domain containing 1" Q8NFD2 11 113387791-113400418 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.7;tongue: 6.3" "Cell type enhanced" "Detected in some" 10 "Ciliated cells: 1.4;Horizontal cells: 1.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "basophil: 1.4;naive B-cell: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 2.0;hTCEpi: 6.7;RT4: 3.2;U-266/70: 1.3" "Not detected" "Not detected" HPA012813 Uncertain NA NA "HPA012813: AB_1844832" "unprognostic (5.63e-3)" "unprognostic (6.67e-3)" "unprognostic (5.09e-3)" "unprognostic (6.27e-3)" "unprognostic (5.56e-4)" "unprognostic (7.02e-2)" "unprognostic (2.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.50e-1)" "unprognostic (3.15e-1)" "unprognostic (3.36e-2)" "unprognostic (2.18e-1)" "unprognostic (5.39e-6)" "unprognostic (3.17e-2)" "unprognostic (3.83e-2)" "unprognostic (2.79e-1)" "unprognostic (4.65e-2)" 0.6 0.5 0.6 0.6 2.0 0.4 1.2 0.6 1.4 1.5 0.6 0.6 0.6 0.4 0.7 0.9 0.6 3.3 0.6 0.6 0.6 1.2 0.6 0.6 0.6 1.1 0.6 0.6 1.0 0.6 0.4 4.7 0.6 0.6 1.9 0.1 0.6 1.8 1.0 0.7 9.7 0.6 0.6 2.3 0.9 0.2 1.0 0.6 0.6 1.2 6.3 1.5 0.6 1.2 1.3 0.2 1.4 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 2.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.4 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.1 0.3 3.2 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.2 0.0 1.3 0.6 0.0 0.0 0.2 0.0 1.4 0.1 0.2 0.4 0.1 0.1 0.0 0.1 0.0 0.0 1.3 0.2 0.1 0.7 0.1 0.0 0.2 0.0 0.1 0.6 2.0 0.6 1.4 0.6 1.2 0.6 0.6 0.6 0.6 0.0 0.3 0.0 0.6 0.6 0.9 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 ARAF ARAF1 ENSG00000078061 "A-Raf proto-oncogene, serine/threonine kinase" P10398 X 47561100-47571920 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046188, HPA066326" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" Nucleoplasm "HPA046188: AB_2679578, HPA066326: AB_2685659" "unprognostic (1.21e-1)" "unprognostic (5.69e-3)" "unprognostic (2.47e-2)" "unprognostic (2.10e-2)" "unprognostic (7.63e-2)" "unprognostic (9.35e-2)" "unprognostic (1.79e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "unprognostic (6.75e-2)" "unprognostic (8.65e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.97e-1)" "unprognostic (2.01e-1)" "unprognostic (6.37e-2)" "unprognostic (4.71e-2)" 22.2 24.2 10.9 16.5 15.5 41.9 19.5 16.0 13.7 18.0 23.2 21.1 24.1 17.8 21.3 18.4 19.4 18.7 21.0 28.6 12.8 7.3 28.0 49.6 21.8 20.2 16.4 9.5 23.4 35.1 28.1 16.9 25.3 13.5 23.5 15.8 25.4 22.1 18.5 60.8 18.9 23.8 18.6 11.2 27.4 24.2 10.2 16.3 27.7 23.1 23.9 27.3 20.2 16.9 23.9 34.3 36.1 38.4 22.4 29.1 27.5 20.3 29.3 12.6 20.2 19.2 15.3 17.0 17.2 18.2 25.7 23.7 23.9 25.0 12.1 14.1 23.0 21.6 28.7 22.2 23.7 14.8 22.3 26.1 12.1 31.1 12.3 27.0 24.0 37.2 20.1 24.2 24.5 21.5 17.0 19.7 15.4 22.5 23.9 17.4 34.4 17.4 25.9 18.1 17.2 32.8 16.2 16.4 27.3 14.7 19.5 14.3 11.0 18.5 17.1 10.1 20.8 32.2 18.2 18.7 16.7 18.8 33.3 17.3 31.0 19.8 9.4 22.2 27.2 13.3 23.9 29.0 36.1 29.1 35.4 26.9 21.4 25.5 26.7 34.3 23.9 22.7 26.7 23.6 22.4 38.4 24.7 25.1 27.5 10.9 15.5 16.0 13.7 12.8 7.3 16.4 9.5 13.5 16.3 14.9 36.4 18.8 19.6 14.0 4.0 23.6 30.6 8.1 10.3 17.4 9.8 27.3 19.9 24.2 1.1 17.9 37.6 0.0 29.9 25.3 15.5 19.0 16.1 35.8 24.8 12.7 30.5 22.7 22.7 3.0 16.1 21.7 32.1 55.1 36.8 13.3 23.6 40.2 16.6 22.1 8.2 19.4 18.6 5.6 10.2 14.2 37.3 27.4 26.6 21.6 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222484-108369102 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 198.3;Rod photoreceptor cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Enhanced Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB000102: , HPA067142: AB_2685789" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 8.3 10.9 12.7 26.5 19.3 16.8 9.4 17.7 14.4 10.9 8.5 10.9 8.8 6.0 11.2 11.4 6.9 9.5 9.2 9.6 12.4 8.5 7.7 9.5 10.1 33.4 19.6 6.7 20.5 20.7 15.7 29.2 8.8 14.5 9.1 7.9 7.2 15.1 9.8 6.2 8.4 16.5 10.6 23.4 22.6 8.9 6.1 17.9 19.5 10.7 5.1 26.9 10.7 10.7 13.7 6.1 13.5 12.5 7.6 18.5 4.4 2.7 3.9 7.7 4.1 10.0 14.6 2.0 6.1 6.8 3.5 5.9 4.8 6.5 9.6 9.1 4.9 5.6 4.1 5.8 5.1 5.5 7.7 3.4 8.7 4.8 4.8 5.3 10.5 9.4 9.4 3.2 5.4 10.4 7.7 7.4 8.2 8.4 6.6 6.9 2.0 7.1 9.7 6.3 4.1 3.9 5.6 5.3 15.1 4.0 5.5 5.2 6.4 7.1 3.3 10.5 7.1 5.0 5.9 11.5 8.8 4.9 5.0 5.7 4.4 4.6 48.5 5.8 11.5 9.8 13.5 5.7 3.8 14.9 5.3 10.4 11.1 10.5 11.3 2.7 13.7 18.5 17.9 10.8 7.6 12.5 6.1 5.3 4.4 12.7 19.3 17.7 14.4 12.4 8.5 19.6 6.7 14.5 17.9 35.7 21.0 122.7 17.4 11.2 101.7 35.4 10.2 13.4 19.4 21.0 198.3 14.8 5.0 7.7 12.8 18.8 4.9 0.0 10.6 10.5 26.4 9.5 12.7 21.2 26.0 57.2 19.5 36.8 82.2 2.7 36.5 48.1 25.3 9.0 15.9 35.9 7.6 10.5 26.2 10.3 196.6 25.8 17.3 18.7 33.6 10.8 3.5 111.7 11.7 9.9 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449235-142578826 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cone photoreceptor cells: 35.3;Spermatocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No Nucleoplasm "Golgi apparatus" "HPA054320: AB_2682448" "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavorable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 10.5 24.3 7.7 11.4 15.9 10.1 14.8 11.3 14.6 10.1 8.5 10.0 10.4 6.0 14.7 16.8 9.4 12.1 9.3 8.8 9.8 7.1 9.6 12.0 10.3 16.0 10.0 8.1 12.3 13.6 18.0 22.5 8.8 12.5 11.0 11.2 9.5 12.5 10.8 7.7 11.2 10.9 9.8 8.8 14.2 9.0 15.3 9.7 19.0 13.8 7.7 15.1 10.9 10.6 5.8 2.8 2.2 4.0 6.7 6.0 0.8 22.7 11.2 7.5 8.5 10.7 11.8 8.9 12.6 7.1 9.4 9.7 5.2 7.3 18.6 13.0 8.9 12.3 14.8 11.0 11.6 14.2 5.9 7.2 10.2 8.5 5.1 4.7 17.1 5.7 9.2 6.4 8.9 10.6 6.4 9.7 9.7 7.1 8.4 9.6 10.0 12.9 7.1 7.2 14.9 8.0 10.7 10.9 13.5 9.5 10.6 5.3 5.4 23.2 8.4 8.2 7.1 12.2 6.9 12.5 9.6 4.8 12.4 13.5 11.0 6.5 17.3 12.5 6.7 7.6 0.7 2.7 2.2 4.4 4.0 6.0 3.1 3.2 4.2 2.8 5.8 4.1 4.0 1.7 6.7 2.5 2.5 2.4 0.8 7.7 15.9 11.3 14.6 9.8 7.1 10.0 8.1 12.5 9.7 6.0 8.8 13.4 6.5 3.5 14.7 7.1 7.6 18.7 6.8 3.5 35.3 6.6 0.0 5.3 12.0 7.1 2.1 0.0 4.3 3.3 4.8 6.7 1.1 6.0 5.7 7.9 7.5 8.6 9.1 6.9 6.1 6.9 10.1 4.6 5.4 4.8 6.2 0.0 6.7 4.1 23.4 0.0 6.4 42.3 15.8 4.0 4.2 5.1 7.0 5.2 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 32.3;testis: 41.1" "Cell type enhanced" "Detected in many" 8 "Erythroid cells: 70.0;Extravillous trophoblasts: 59.5;granulocytes: 55.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved Nucleoplasm,Centrosome,Cytosol Yes Yes "Nucleoplasm, Centrosome, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 3.7 2.3 1.5 12.7 1.3 8.3 3.0 1.3 1.8 1.4 6.7 1.3 0.8 7.3 1.8 1.2 7.7 1.1 3.7 4.1 1.1 1.1 2.4 5.1 2.9 12.3 1.6 0.9 8.3 1.4 0.3 0.7 6.1 1.5 1.0 8.3 1.5 2.7 0.5 6.9 2.1 7.2 2.7 1.3 7.4 4.3 41.1 1.1 32.3 1.2 5.9 13.3 2.4 2.4 3.9 5.2 6.0 8.7 2.0 6.6 2.6 33.0 24.4 16.3 11.5 0.9 2.1 20.7 27.1 12.7 65.7 27.7 68.2 23.2 10.8 18.7 11.1 34.1 26.7 29.0 18.2 70.0 9.8 11.1 19.3 25.0 42.5 0.5 25.8 27.2 1.0 1.9 22.7 20.4 5.2 15.3 17.7 21.9 8.6 27.9 33.7 15.4 20.0 14.9 27.1 25.1 11.7 31.5 12.0 10.5 8.7 14.1 7.6 37.9 43.6 18.2 15.6 25.8 16.1 8.8 28.6 28.3 15.8 38.2 12.1 14.0 18.8 15.4 15.0 23.6 0.2 5.3 6.0 1.9 8.7 2.9 3.9 3.3 1.9 5.2 1.4 1.5 1.5 3.7 2.0 4.8 1.2 6.6 2.6 1.5 1.3 1.3 1.8 1.1 1.1 1.6 0.9 1.5 1.1 0.0 3.2 4.5 1.1 1.0 1.0 3.4 2.5 1.4 2.3 3.5 2.0 9.8 1.7 3.9 16.9 1.6 5.3 70.0 4.2 59.5 3.8 0.7 55.2 2.4 14.8 1.6 5.8 3.1 2.4 9.5 1.4 5.5 0.0 18.0 5.7 3.5 3.6 3.5 0.4 1.9 2.5 6.5 2.1 16.2 31.6 1.0 6.9 4.9 9.8 1.4 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;lymphoid tissue: 59.9" "Group enriched" "Detected in many" 6 "Erythroid cells: 46.7;Extravillous trophoblasts: 76.2;Hofbauer cells: 23.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 10.9" "Lineage enriched" "Detected in many" 5 "T-cells: 10.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.2 1.3 0.4 22.1 0.6 19.7 2.0 0.6 0.6 2.6 5.8 0.5 0.9 5.9 0.9 1.3 17.1 0.3 2.2 1.0 0.4 0.2 1.4 1.8 2.4 17.8 0.4 0.4 0.8 0.6 0.0 0.4 3.8 0.8 0.9 5.5 0.7 2.7 0.4 2.1 5.0 8.1 1.3 0.7 11.2 4.2 1.2 0.4 59.9 0.5 8.0 19.1 2.1 5.0 2.3 0.8 1.2 0.6 0.5 10.9 1.4 41.6 28.6 42.7 20.5 0.9 1.4 16.4 20.0 10.8 41.5 38.3 37.0 12.6 41.6 10.4 7.9 17.3 30.7 30.9 13.7 34.3 18.2 50.8 24.8 16.4 31.2 0.1 13.0 24.4 0.7 0.6 24.3 15.2 4.1 19.0 27.4 15.4 16.1 18.1 19.8 47.5 18.6 26.5 13.7 12.7 32.2 39.3 17.2 9.0 8.2 9.3 13.2 17.8 8.0 13.6 13.3 14.0 8.8 7.4 16.6 17.1 14.9 52.0 11.8 7.8 31.3 8.0 19.9 33.6 0.0 0.6 0.9 0.6 0.4 0.2 1.6 1.9 3.1 0.8 2.3 0.2 1.0 1.2 0.5 0.3 0.2 10.9 1.4 0.4 0.6 0.6 0.6 0.4 0.2 0.4 0.4 0.8 0.4 0.0 0.3 2.2 0.3 3.9 0.0 1.1 0.0 0.0 3.4 0.0 0.0 5.1 0.0 0.2 0.0 0.0 1.4 46.7 0.0 76.2 4.7 0.4 4.6 0.6 23.9 0.0 0.0 4.9 6.3 0.0 0.6 4.4 1.7 0.0 4.2 0.0 0.2 2.9 0.0 0.0 0.0 0.0 0.3 0.7 2.0 2.0 7.6 2.5 6.3 1.4 AURKC "ARK3, AurC, STK13" ENSG00000105146 "Aurora kinase C" Q9UQB9 19 57230802-57235548 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "testis: 72.0" "Group enriched" "Detected in many" 4 "Early spermatids: 101.7;Spermatocytes: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "NTERA-2: 30.0" "Low region specificity" "Detected in all" HPA034859 Uncertain NA NA "HPA034859: AB_10670298" "unprognostic (7.27e-2)" "unprognostic (1.76e-1)" "unprognostic (6.45e-2)" "unprognostic (8.07e-3)" "unprognostic (3.29e-1)" "unprognostic (5.99e-2)" "unprognostic (1.11e-2)" "unprognostic (7.02e-2)" "unprognostic (1.13e-1)" "unprognostic (2.09e-1)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (1.20e-5)" "unprognostic (4.26e-2)" "unprognostic (1.61e-1)" "unprognostic (1.55e-1)" "unprognostic (6.46e-4)" 0.6 0.5 0.9 0.9 1.2 0.7 1.5 0.7 2.0 0.4 0.6 0.6 0.2 0.0 0.8 1.3 0.5 0.6 2.6 0.9 0.9 1.1 0.8 1.8 1.3 2.2 1.2 0.2 0.4 0.5 0.1 1.3 1.2 1.7 0.5 0.8 1.1 0.5 0.9 2.3 0.6 0.4 1.1 2.1 3.4 0.4 72.0 0.6 0.7 0.8 1.0 1.3 0.5 0.4 2.1 1.0 1.7 1.0 1.0 0.6 0.2 0.2 0.1 0.7 0.3 0.2 0.7 0.3 1.3 0.6 0.9 3.5 0.9 0.1 0.0 0.1 0.5 0.8 0.0 0.0 0.7 0.6 0.0 3.8 0.1 0.3 0.0 1.1 0.0 0.2 0.9 0.7 0.7 0.5 1.1 0.6 0.4 0.1 0.0 1.2 0.0 1.1 0.6 30.0 0.1 0.8 0.1 0.2 0.6 0.7 1.2 1.4 0.4 0.0 0.2 0.1 0.1 0.1 1.3 0.3 0.2 4.2 0.3 0.7 1.4 1.9 0.6 0.8 0.0 0.0 0.0 0.1 1.7 0.6 1.0 0.0 1.9 0.0 0.0 0.9 2.1 0.0 0.0 0.1 1.0 0.3 1.0 0.0 0.2 0.9 1.2 0.7 1.6 0.9 1.1 1.2 0.2 1.7 0.6 0.0 0.3 0.0 0.6 1.0 2.5 1.2 0.0 1.4 3.4 1.8 0.0 0.4 1.7 1.5 101.7 0.6 0.0 0.0 0.9 0.7 0.4 1.1 0.0 0.0 3.2 0.0 1.7 1.8 1.3 11.5 1.4 1.0 5.0 1.8 0.0 1.7 0.9 0.3 0.4 0.3 0.8 6.5 0.5 69.6 19.2 1.0 0.2 0.0 0.4 1.4 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219203-41261766 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 13 "Kupffer cells: 104.4;Sertoli cells: 207.0;Smooth muscle cells: 341.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 8.8;plasmacytoid DC: 18.3" "Group enriched" "Detected in many" 14 "dendritic cells: 18.3;NK-cells: 8.8" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 67.0;U-251 MG: 71.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 61000000 "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 38.0 15.4 10.6 11.7 12.7 1.3 27.1 6.3 12.1 26.2 26.8 13.4 8.1 9.1 28.0 19.4 21.8 17.4 17.8 18.5 11.5 6.1 7.8 13.0 20.0 7.6 10.6 9.3 20.9 5.1 9.6 5.6 26.6 10.1 19.5 10.2 16.8 7.8 20.4 14.1 13.8 12.8 29.4 10.7 27.3 16.2 22.4 10.4 3.4 12.0 8.4 5.8 35.6 18.3 0.1 18.3 0.9 0.2 8.8 0.3 0.2 53.3 21.4 1.3 0.1 4.8 4.9 0.0 42.3 38.1 62.2 38.6 1.1 25.1 0.0 17.2 67.0 32.5 4.5 0.0 28.5 53.6 0.0 0.0 0.0 14.2 0.8 17.6 0.0 0.0 3.7 0.5 36.6 56.9 35.3 23.0 0.0 2.0 0.0 38.5 0.0 0.0 0.0 0.5 0.1 10.3 0.0 22.7 0.0 27.8 0.0 0.0 0.0 10.9 0.0 0.2 8.2 0.1 0.9 47.2 44.1 30.1 42.1 71.7 0.0 0.1 0.1 29.4 0.0 32.8 0.9 0.2 0.1 0.1 0.2 0.2 0.1 0.3 0.1 4.2 0.1 0.2 0.2 0.3 8.8 0.1 18.3 0.2 0.2 10.6 12.7 6.3 12.1 11.5 6.1 10.6 9.3 10.1 10.4 8.9 2.2 0.5 72.4 37.1 0.0 4.2 0.0 4.0 5.7 5.2 0.0 2.3 0.0 4.0 8.6 2.9 0.0 0.0 0.2 1.7 91.1 28.0 0.0 0.0 26.7 1.6 0.0 13.5 104.4 2.7 57.0 49.8 25.3 4.6 0.0 28.7 8.9 0.0 75.0 0.0 1.1 207.0 341.9 0.5 2.1 25.5 9.6 2.5 0.0 26.4 BCKDK ENSG00000103507 "Branched chain ketoacid dehydrogenase kinase" O14874 16 31106107-31112791 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Autism, Autism spectrum disorder, Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 26.8;granulocytes: 26.6;monocytes: 33.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017995, HPA056067" Supported Supported Mitochondria NA NA Mitochondria "HPA017995: AB_1845309, HPA056067: AB_2683024" "unprognostic (1.37e-1)" "unprognostic (2.57e-1)" "unprognostic (6.94e-2)" "unprognostic (5.20e-2)" "unprognostic (5.39e-2)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (5.47e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.24e-2)" "unprognostic (2.66e-3)" "unprognostic (4.85e-2)" "unprognostic (3.93e-2)" "unprognostic (1.00e-1)" "unprognostic (4.97e-2)" 15.4 29.7 11.9 13.1 15.0 9.4 18.3 18.8 21.3 11.7 14.1 9.6 19.9 11.2 14.8 14.9 14.9 13.8 15.1 39.2 14.2 10.3 21.3 46.5 18.2 32.5 10.7 17.3 15.1 52.4 17.4 8.9 11.4 13.2 14.9 9.9 10.4 33.9 25.7 67.7 21.5 12.2 19.9 15.6 16.0 19.9 11.2 9.3 8.0 11.7 25.9 10.6 15.3 12.0 6.9 26.8 26.6 33.0 6.3 6.8 13.6 18.2 20.5 11.6 17.4 14.3 14.4 12.6 15.9 19.6 24.8 24.3 13.4 12.2 17.1 23.1 19.8 12.1 12.7 8.2 27.7 16.0 13.8 25.4 18.5 13.9 24.3 25.2 9.6 17.0 21.1 11.2 21.2 17.7 22.8 26.4 13.1 9.3 16.2 37.1 31.1 8.8 12.7 9.8 8.5 16.6 17.9 16.9 31.5 18.9 12.6 17.9 16.4 12.3 30.5 9.9 10.4 18.4 9.2 16.9 18.9 10.9 19.4 13.2 16.9 6.0 6.1 21.5 13.9 17.7 12.2 33.0 23.1 5.7 27.4 5.6 6.9 5.2 4.2 26.8 5.4 4.4 5.0 26.6 6.3 19.3 5.8 6.8 13.6 11.9 15.0 18.8 21.3 14.2 10.3 10.7 17.3 13.2 9.3 17.9 17.8 27.4 21.2 16.5 11.0 32.1 25.5 13.4 9.1 19.2 0.0 47.3 68.0 57.7 2.2 20.9 39.3 0.0 68.3 54.7 20.7 26.1 33.4 34.7 83.9 11.1 19.1 27.0 41.9 3.6 19.2 56.7 11.8 95.6 20.5 22.1 49.3 40.3 24.1 65.3 7.2 45.3 28.9 16.7 15.2 24.0 58.0 14.4 26.7 19.3 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564604 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "blood: 47.8;intestine: 23.5;lymphoid tissue: 39.8" "Cell type enriched" "Detected in some" 52 "B-cells: 93.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 47.8;naive B-cell: 33.9" "Lineage enriched" "Detected in many" 5 "B-cells: 47.8" "Cell line enhanced" "Detected in some" "Daudi: 44.0;REH: 11.9;RPMI-8226: 14.5;U-698: 21.5;U-87 MG: 9.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005093, HPA069571" Approved Uncertain Nucleoplasm NA NA Nucleoplasm "CAB005093: AB_2274756, HPA069571: AB_2732137" "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.2 0.1 32.3 0.1 1.7 0.2 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.0 1.9 0.2 0.4 0.3 0.1 0.1 1.3 0.5 0.6 27.6 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.4 0.3 2.4 0.0 0.1 0.1 23.5 0.0 0.1 31.9 1.4 0.2 0.0 3.9 0.7 0.4 39.8 2.5 0.4 47.8 4.3 0.1 0.0 0.0 9.8 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 11.9 0.0 14.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.3 3.8 21.5 9.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 9.8 47.8 0.3 1.1 0.0 33.9 0.2 0.1 0.1 0.0 0.0 4.3 0.4 1.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 93.8 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BMP2K "BIKe, DKFZp434K0614" ENSG00000138756 "BMP2 inducible kinase" Q9NSY1 4 78776342-78916372 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "granulocytes: 124.9;Hofbauer cells: 112.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 38.8;HMC-1: 42.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026436, HPA026451, HPA026501" Approved Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA026436: AB_10600102, HPA026451: AB_10600228, HPA026501: AB_10601341" "unprognostic (7.96e-2)" "unprognostic (3.68e-1)" "prognostic favorable (1.74e-4)" "unprognostic (9.08e-2)" "unprognostic (1.97e-1)" "unprognostic (9.73e-3)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.39e-1)" "unprognostic (9.60e-2)" "unprognostic (9.90e-2)" "unprognostic (9.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.18e-2)" 11.4 11.1 15.6 18.6 15.0 15.3 12.0 8.2 12.7 11.1 13.9 20.3 2.1 8.0 11.3 9.6 15.7 10.0 12.3 17.0 18.0 9.5 8.3 10.2 14.1 22.9 20.9 12.0 6.5 6.4 7.7 7.8 14.4 14.5 8.4 18.9 11.4 10.2 6.0 7.5 14.5 15.9 10.4 28.3 19.2 7.4 19.6 16.5 19.9 12.5 5.9 24.4 9.7 12.8 2.7 1.7 3.8 2.6 0.4 0.4 0.5 5.5 2.0 3.0 4.0 6.0 5.8 2.4 5.4 8.3 6.0 7.9 3.8 2.9 6.7 2.7 25.8 5.2 1.3 3.6 4.3 11.0 1.9 1.3 38.8 2.4 1.7 6.7 8.1 42.0 8.4 5.6 9.4 8.7 3.2 8.1 4.9 10.4 19.5 7.1 1.2 4.8 3.4 1.4 3.7 1.4 7.0 5.5 1.6 7.3 3.0 4.8 2.6 7.8 4.0 4.7 3.8 1.4 4.2 7.9 5.9 2.3 9.8 5.7 3.6 1.4 2.6 5.2 10.2 4.1 0.4 2.2 1.2 0.1 0.9 0.1 2.7 0.1 0.0 1.7 2.7 0.4 0.2 3.8 0.4 2.6 1.3 0.0 0.5 15.6 15.0 8.2 12.7 18.0 9.5 20.9 12.0 14.5 16.5 26.8 18.1 10.4 3.8 22.1 9.6 5.7 2.5 6.7 6.8 7.0 3.9 4.0 0.0 7.0 11.1 12.4 19.7 46.7 7.6 11.6 12.4 6.3 124.9 16.3 112.6 9.5 6.4 30.7 61.7 7.6 7.5 31.6 27.0 22.6 41.6 46.4 10.6 48.2 6.3 18.1 8.4 6.5 7.4 24.1 9.6 27.5 2.9 3.9 21.8 2.3 BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932838 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol NA NA Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" 8.9 7.0 9.4 7.9 12.4 0.9 10.7 14.1 9.2 19.4 20.6 10.9 7.7 6.2 16.3 12.3 8.4 10.9 10.8 11.0 7.7 6.1 8.2 4.6 7.4 2.9 7.3 7.6 16.1 10.6 10.0 14.0 7.4 8.5 12.8 9.3 10.9 12.6 14.2 8.4 11.3 9.8 16.5 12.2 3.4 12.1 7.8 9.2 0.3 19.4 7.8 5.7 16.0 11.4 1.8 1.1 3.6 0.8 0.9 1.4 0.3 7.3 3.7 14.3 12.1 7.5 4.8 2.5 7.4 7.7 4.3 5.1 6.2 6.4 2.2 3.4 9.4 3.1 7.8 6.3 8.0 6.4 2.4 3.6 2.8 3.5 10.3 4.0 3.8 19.7 4.2 3.4 5.8 4.3 6.4 0.0 4.1 4.4 1.5 5.0 3.1 2.6 3.1 7.7 2.6 1.7 0.0 5.6 0.0 8.9 6.9 1.4 4.6 8.2 4.2 4.9 18.2 7.1 1.9 3.7 3.1 5.0 6.4 6.8 0.4 6.8 2.8 2.7 2.6 2.5 2.0 0.8 0.6 1.4 0.5 0.9 1.8 1.4 1.2 0.3 1.5 1.0 1.1 3.6 0.9 0.6 1.1 0.7 0.3 9.4 12.4 14.1 9.2 7.7 6.1 7.3 7.6 8.5 9.2 32.8 24.8 0.0 6.7 10.8 6.0 19.0 10.2 13.4 9.1 10.4 19.6 10.0 1.7 9.8 0.6 2.1 9.0 0.0 8.1 0.7 13.3 12.9 15.0 7.2 2.7 11.1 17.3 8.0 4.0 1.7 31.1 3.5 8.5 1.0 13.6 12.9 7.7 3.5 29.4 4.7 19.0 6.5 14.1 2.3 3.6 8.5 4.2 0.0 10.0 4.2 BMPR1B "ALK6, CDw293" ENSG00000138696 "Bone morphogenetic protein receptor type 1B" O00238 4 94757968-95158448 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chondrogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix, uterine: 28.0;ductus deferens: 25.1;prostate: 25.3;seminal vesicle: 32.0" "Group enriched" "Detected in many" 5 "Ciliated cells: 14.7;Club cells: 22.7;Collecting duct cells: 57.6;Glandular cells: 28.8;Intestinal endocrine cells: 17.6;Melanocytes: 27.0;Muller glia cells: 44.8" "Cancer enhanced" "Detected in many" "breast cancer: 32.4;prostate cancer: 24.7" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 18.7;MCF7: 9.4;SH-SY5Y: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.40e-3)" "prognostic favorable (2.84e-4)" "unprognostic (1.57e-1)" "unprognostic (4.22e-2)" "unprognostic (1.92e-1)" "unprognostic (2.86e-2)" "unprognostic (2.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (3.93e-1)" "unprognostic (1.62e-3)" "unprognostic (7.89e-4)" "unprognostic (6.22e-2)" "unprognostic (3.81e-3)" "unprognostic (2.63e-2)" 1.1 5.6 12.7 0.8 15.0 0.7 1.7 11.6 12.7 28.0 1.2 5.5 25.1 0.7 5.3 3.2 1.1 14.3 3.4 1.3 13.4 5.9 9.3 1.4 2.4 0.5 5.4 8.6 7.6 1.7 0.6 2.4 1.2 12.1 25.3 0.8 0.7 1.4 32.0 3.3 1.4 0.6 1.2 7.5 1.4 2.8 4.3 11.2 10.8 0.8 0.1 0.6 0.7 0.7 0.4 0.5 1.9 0.9 0.8 1.6 0.3 0.0 18.7 5.0 0.0 2.0 4.6 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.2 0.8 0.0 1.0 2.9 6.9 0.0 0.0 4.6 0.0 1.1 0.0 0.5 0.4 0.0 2.8 7.6 2.8 5.7 0.3 0.0 0.0 0.0 0.0 7.2 9.4 0.6 0.1 1.8 0.1 3.2 0.1 2.8 0.1 3.6 0.1 0.2 15.6 0.2 2.5 2.5 0.7 1.9 0.0 0.0 4.0 3.2 0.1 3.4 0.0 0.0 0.0 1.5 0.0 0.4 1.9 0.3 0.5 0.4 0.5 0.7 0.4 0.6 0.3 0.3 0.3 0.5 0.5 0.8 0.8 0.9 0.5 1.6 0.3 12.7 15.0 11.6 11.8 13.4 5.9 5.4 8.6 12.1 11.2 6.0 0.0 0.0 1.3 2.4 0.2 3.6 5.1 14.7 22.7 57.6 0.0 0.0 1.7 2.9 1.1 0.3 0.0 0.0 0.3 0.2 1.4 28.8 0.0 0.0 0.1 0.0 17.6 4.9 0.0 1.6 2.8 0.3 27.0 0.0 0.0 44.8 0.7 0.0 3.5 0.0 1.2 0.0 1.4 1.6 1.3 1.9 0.0 0.0 0.0 1.0 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376936-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.1 15.0 12.1 9.8 14.2 1.1 10.2 9.5 17.1 15.7 11.7 8.2 6.5 5.5 12.9 10.2 10.6 10.3 13.2 14.6 10.8 13.5 10.7 11.5 24.9 4.4 10.4 14.5 12.0 7.0 15.5 6.1 21.7 10.8 11.0 7.7 11.4 7.1 9.1 10.6 7.2 8.1 15.3 7.5 8.9 7.2 12.9 3.8 3.9 11.6 5.2 5.4 11.1 8.9 1.6 2.6 0.9 2.7 1.1 3.6 0.9 5.7 5.4 5.6 8.8 14.0 13.6 10.8 12.0 12.1 10.5 10.5 4.7 8.7 2.0 14.0 24.2 9.0 10.9 7.3 9.3 16.5 6.0 5.0 6.1 5.8 7.3 9.7 1.7 4.8 9.9 8.8 7.7 10.3 16.2 30.2 2.5 3.9 10.0 12.9 10.8 1.4 1.6 3.1 2.8 5.0 3.9 11.0 3.0 8.9 12.3 5.7 5.7 12.8 7.6 14.1 14.3 5.9 4.0 33.3 21.4 11.4 7.3 7.2 1.4 1.7 0.6 5.1 3.9 6.2 0.5 2.0 0.9 3.4 1.8 2.5 1.5 1.3 2.2 2.3 1.6 2.7 1.4 0.6 1.1 2.7 2.6 3.6 0.9 12.1 14.2 9.5 17.1 10.8 13.5 10.4 14.5 10.8 3.8 98.3 38.9 17.1 16.1 29.8 51.7 46.4 12.7 21.4 39.8 19.2 76.6 14.0 1.7 27.3 2.4 119.4 12.7 0.0 24.7 19.4 40.9 19.9 23.1 15.5 16.2 33.4 24.1 109.2 20.0 2.3 31.4 17.4 40.5 15.4 16.3 38.7 36.3 20.9 40.3 10.7 29.9 64.7 45.7 17.7 11.1 31.5 16.7 13.8 13.4 22.7 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 57.1" "Group enriched" "Detected in some" 9 "Endothelial cells: 18.5;Ito cells: 51.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 17 "neutrophil: 10.5" "Lineage enriched" "Detected in single" 105 "granulocytes: 10.5" "Cell line enriched" "Detected in single" 121 "HUVEC TERT2: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 8.2 0.3 0.1 1.0 0.7 3.6 5.4 0.1 0.3 2.2 5.5 0.1 4.6 2.4 2.6 57.1 1.5 2.5 2.6 10.5 0.5 0.0 0.2 0.9 3.7 6.5 0.4 0.0 1.4 0.9 0.2 0.6 2.6 0.7 2.2 1.4 0.5 1.5 0.6 4.2 1.6 5.5 2.2 0.4 2.4 1.5 1.9 0.1 0.2 2.2 1.1 0.8 2.8 2.4 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.3 0.5 0.0 0.4 0.0 0.7 0.1 0.0 1.4 0.0 0.5 0.3 0.0 1.2 0.0 1.4 0.0 1.8 0.0 0.0 0.0 0.0 0.0 18.5 0.0 0.0 0.2 0.0 0.5 0.4 0.0 0.2 0.1 0.0 4.1 51.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924928 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol No No Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336" "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 13.1 12.1 20.1 16.5 20.4 27.8 14.2 29.9 21.5 12.4 12.3 9.5 12.5 9.3 15.3 17.0 11.8 11.5 12.0 13.6 13.2 12.2 13.7 12.8 15.9 13.3 9.9 17.8 16.8 13.2 28.9 24.8 13.7 15.3 14.5 11.0 10.7 11.6 16.6 12.9 15.6 10.5 13.0 10.9 12.3 12.0 24.9 12.2 13.5 16.6 7.5 12.1 18.6 18.1 2.6 1.9 7.5 2.4 7.0 5.6 1.1 5.5 4.7 6.9 8.3 8.4 11.0 11.1 6.2 6.6 5.0 7.2 5.1 6.0 9.5 4.8 6.4 8.0 3.1 6.1 4.9 9.3 8.8 5.0 6.2 4.6 4.7 7.2 10.0 6.2 7.3 5.6 5.3 11.1 7.4 5.8 7.1 9.7 17.1 8.8 2.9 13.3 10.5 6.4 5.4 3.0 8.7 5.9 7.7 4.9 10.7 8.1 6.8 7.2 4.4 6.5 7.1 4.1 6.8 8.6 5.5 4.2 11.7 5.0 19.8 11.2 15.2 8.9 10.1 5.9 3.3 2.0 7.5 3.1 1.7 2.1 2.6 3.0 2.4 1.6 2.6 5.6 2.8 4.1 7.0 2.4 1.9 2.7 1.1 20.1 20.4 29.9 21.5 13.2 12.2 9.9 17.8 15.3 12.2 20.8 34.2 19.5 20.3 19.2 29.1 12.7 5.1 24.1 25.0 24.4 33.4 12.4 6.6 10.9 55.6 17.1 7.5 0.0 8.6 10.3 13.1 23.9 24.3 8.7 7.9 23.8 18.4 8.6 14.8 30.8 15.3 17.2 15.1 10.0 8.1 11.8 12.5 6.6 9.6 9.6 32.5 6.5 17.3 33.7 23.0 21.0 63.2 17.5 8.1 23.8 BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312533 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.0" "Cell type enhanced" "Detected in many" 13 "Bipolar cells: 30.8;Enterocytes: 12.3;Horizontal cells: 36.5" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 26.2;SH-SY5Y: 23.6;WM-115: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA Nucleoplasm "Cell Junctions" "HPA021212: AB_1845455, HPA061719: AB_2684593" "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" 1.4 9.8 28.6 3.2 23.6 1.0 1.6 26.7 65.0 1.8 2.2 7.9 0.1 3.3 5.4 3.7 3.0 2.3 3.9 6.5 33.4 20.0 1.4 0.8 1.7 2.4 20.4 14.8 2.4 2.6 12.4 11.0 1.5 13.3 3.8 1.9 2.8 2.5 4.6 1.0 1.1 2.6 4.9 9.2 1.5 1.9 4.4 7.2 0.0 3.0 0.0 1.6 3.2 0.7 0.0 0.3 0.0 0.9 0.1 0.8 0.2 0.3 1.3 15.5 8.2 0.0 0.6 0.1 2.4 3.4 3.3 4.9 5.9 2.7 3.1 1.7 2.8 3.1 0.1 3.2 0.1 3.1 14.6 12.8 2.0 1.6 0.6 3.3 0.6 6.0 2.2 0.3 3.4 0.0 12.9 0.1 8.2 2.8 19.1 3.0 0.8 3.7 0.7 11.2 0.3 1.0 8.5 3.9 0.5 0.2 0.0 26.2 23.6 0.0 0.4 5.7 4.6 1.3 1.7 0.0 6.4 6.8 3.5 4.6 15.8 11.6 7.1 6.5 1.4 21.4 0.0 0.9 0.0 0.1 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.2 28.6 23.6 26.7 40.2 33.4 20.0 20.4 14.8 13.3 7.2 0.0 2.2 0.0 1.0 0.1 30.8 0.8 0.0 0.0 1.2 1.8 2.0 0.0 0.0 0.3 0.8 0.3 12.3 0.0 0.0 0.0 0.5 0.8 0.0 0.0 1.4 36.5 3.4 0.0 7.8 0.0 0.6 0.4 0.0 0.0 1.0 3.2 0.2 0.0 4.6 0.8 10.2 0.0 1.0 3.9 6.5 0.0 0.0 0.8 1.2 0.1 BRSK2 "C11orf7, PEN11B, STK29" ENSG00000174672 "BR serine/threonine kinase 2" Q8IWQ3 11 1389899-1462689 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Exocytosis, Mitosis, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 34.9;pancreas: 78.8" "Group enriched" "Detected in some" 6 "Bipolar cells: 79.7;Cone photoreceptor cells: 33.4;Horizontal cells: 65.2;Muller glia cells: 24.5;Rod photoreceptor cells: 27.0" "Cancer enhanced" "Detected in many" "glioma: 3.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 13 "NK-cells: 1.3" "Cell line enhanced" "Detected in some" "AF22: 9.1;AN3-CA: 9.9;CACO-2: 7.9;HAP1: 7.4;NTERA-2: 15.3;SCLC-21H: 35.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073690 Approved "Golgi apparatus" NA NA "Golgi apparatus" "HPA073690: " "unprognostic (5.47e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.05e-2)" "unprognostic (3.63e-1)" "unprognostic (6.42e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (2.31e-1)" "unprognostic (3.17e-7)" "unprognostic (3.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "unprognostic (1.86e-1)" 1.5 3.5 13.6 1.5 12.8 1.3 1.3 30.8 34.9 1.3 1.5 10.0 0.0 1.7 1.4 1.3 1.3 1.4 1.9 1.5 15.6 10.6 1.4 1.3 1.4 1.3 8.3 17.2 1.4 78.8 1.6 4.6 1.8 9.5 1.6 1.4 2.2 1.6 1.4 1.5 1.5 1.9 1.4 6.5 1.3 1.9 5.5 9.2 0.0 1.9 0.0 1.3 1.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 4.0 9.1 9.9 0.1 0.3 0.0 0.1 0.1 0.7 0.3 7.9 0.5 0.0 1.4 0.1 0.1 0.0 7.4 0.0 0.6 0.9 3.9 0.0 0.0 0.1 0.4 0.0 0.3 0.1 0.0 0.0 0.9 0.2 0.0 0.3 0.1 0.0 0.1 0.9 0.0 0.0 15.3 2.7 1.2 0.0 0.0 0.0 0.1 0.1 35.8 5.3 1.8 0.1 2.5 0.2 0.2 0.4 0.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 13.6 12.8 30.8 23.3 15.6 10.6 8.3 17.2 9.5 9.2 0.0 0.0 0.0 0.1 0.2 79.7 2.2 0.0 0.0 0.0 0.0 33.4 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.9 0.0 0.2 0.2 0.0 0.0 0.2 65.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 24.5 0.5 0.0 1.1 0.0 27.0 6.5 8.0 0.7 1.5 0.0 0.0 0.0 0.0 0.0 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 77.5;lymphoid tissue: 37.0" "Cell type enhanced" "Detected in some" 19 "B-cells: 86.8;granulocytes: 203.6;Hofbauer cells: 50.3;Kupffer cells: 53.4;Macrophages: 53.0;monocytes: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "basophil: 77.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 29.5;HEL: 40.9;HMC-1: 147.5;U-937: 21.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 610000 "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 7.3 2.4 3.3 23.5 5.6 14.0 2.6 0.8 3.6 2.3 3.0 4.7 0.3 2.2 1.9 2.6 2.4 2.0 3.7 3.3 3.3 2.5 2.2 2.5 10.7 25.1 5.4 1.2 1.2 1.5 0.2 1.4 3.2 4.1 2.5 4.5 1.5 3.2 1.0 1.0 2.5 12.9 3.3 10.8 37.0 3.1 1.3 6.3 4.0 1.7 1.8 36.7 5.8 2.0 13.7 13.2 77.5 20.7 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 16.4 147.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.3 0.0 0.0 0.0 11.5 0.2 0.0 0.0 12.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.3 0.2 14.0 0.0 21.4 0.0 77.5 11.3 19.3 0.0 18.1 0.0 13.7 0.0 0.0 13.2 13.7 0.0 0.0 4.5 0.0 20.7 6.0 0.0 6.1 3.3 5.6 0.8 3.6 3.3 2.5 5.4 1.2 4.1 6.3 3.0 12.8 86.8 0.1 0.9 0.0 0.4 0.0 0.0 1.2 0.0 0.0 1.1 0.0 0.0 0.2 0.6 0.0 23.3 0.0 0.4 0.5 0.0 203.6 0.0 50.3 0.0 0.0 1.3 53.4 0.0 0.3 53.0 3.3 52.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.4 1.6 0.3 1.6 0.8 0.0 0.1 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637698-110678114 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 56.5;testis: 30.9" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "T-reg: 6.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 68.1" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 1.1 0.9 0.5 15.8 1.0 8.9 0.6 0.3 1.0 1.2 2.8 0.4 0.0 2.4 0.7 2.3 5.8 0.5 1.0 1.1 0.5 0.5 0.9 0.8 2.1 11.6 0.6 0.2 1.0 0.7 0.0 0.4 2.4 0.5 0.7 4.3 0.4 1.4 0.0 0.5 1.8 3.1 1.4 1.3 7.9 1.8 30.9 0.1 56.5 0.6 5.7 12.1 2.5 2.0 1.8 2.4 3.0 0.2 1.4 6.1 1.1 30.3 8.9 23.4 14.7 1.0 1.7 12.4 15.8 10.4 27.5 20.8 18.7 17.5 20.6 9.8 9.1 25.8 13.3 29.9 11.5 34.2 16.3 14.6 68.1 9.5 14.9 0.2 19.6 19.3 0.4 0.7 21.2 10.5 3.9 16.1 23.1 29.8 43.0 22.5 10.0 32.8 16.4 22.6 10.8 16.9 21.8 20.0 31.4 5.6 9.6 15.7 6.8 11.2 9.6 8.5 14.9 7.5 16.6 6.6 12.5 20.5 9.4 21.9 22.5 21.1 25.3 8.5 15.2 22.0 3.0 0.0 0.7 0.6 0.2 0.9 1.8 2.5 1.0 0.8 1.4 1.6 1.5 0.0 1.4 0.1 2.4 6.1 1.1 0.5 1.0 0.3 1.0 0.5 0.5 0.6 0.2 0.5 0.1 0.0 1.0 7.8 0.2 0.5 0.0 0.8 0.0 1.4 2.3 0.0 0.0 1.3 0.0 0.2 8.3 0.0 0.0 0.0 0.0 8.1 0.3 0.2 0.0 0.2 6.6 0.0 0.0 1.3 1.3 4.7 0.3 1.7 0.0 1.0 0.9 0.0 0.1 0.0 0.4 0.0 0.0 6.5 0.0 68.0 14.1 0.4 0.6 2.5 2.0 0.9 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221136 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 49.5;testis: 25.6" "Group enriched" "Detected in many" 7 "Spermatocytes: 66.9;Spermatogonia: 28.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "naive B-cell: 2.8;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA008419 Supported Cytosol Yes Yes Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 1.0 0.9 0.3 18.4 0.6 11.4 1.5 0.4 0.5 1.3 4.0 0.4 0.1 3.3 1.1 0.8 6.5 0.5 1.1 0.6 0.4 0.4 0.8 0.7 1.8 8.7 0.4 0.3 0.6 0.5 0.0 0.4 3.4 0.5 0.6 4.4 0.3 1.6 0.1 0.7 2.3 2.9 1.2 0.6 5.4 1.7 25.6 0.1 49.5 0.5 3.1 10.6 1.1 2.0 2.8 2.8 0.0 0.2 0.7 0.7 0.5 21.8 11.1 35.5 14.1 0.9 2.5 11.5 20.8 11.7 22.3 19.4 16.2 8.4 19.8 11.7 7.5 20.5 24.7 33.5 11.3 24.3 17.0 18.0 28.9 28.7 15.0 0.0 26.1 15.9 0.5 0.6 13.6 12.8 4.4 16.1 22.9 24.9 21.1 22.2 7.4 20.4 15.9 24.0 18.4 12.7 21.9 29.2 15.0 6.8 11.1 23.2 14.3 12.8 12.3 4.5 16.2 14.3 13.5 9.3 17.1 18.1 17.0 18.4 11.1 18.8 32.4 9.1 29.3 22.2 0.0 0.0 0.0 0.2 0.2 0.3 2.4 0.7 0.6 0.7 2.8 0.1 0.4 0.0 0.7 0.1 2.8 0.0 0.5 0.3 0.6 0.4 0.5 0.4 0.4 0.4 0.3 0.5 0.1 3.0 1.4 0.8 0.3 0.7 0.4 0.4 0.0 0.0 3.4 0.0 0.0 1.3 0.0 0.3 2.5 0.0 0.3 0.0 0.0 5.1 0.4 0.2 0.0 0.2 4.3 0.0 0.0 1.3 0.6 2.4 1.4 1.5 0.0 0.0 1.4 0.0 0.8 0.8 0.4 0.0 0.1 6.5 0.0 66.9 28.8 0.3 0.7 0.8 1.7 0.4 CAMK1 CaMKI ENSG00000134072 "Calcium/calmodulin dependent protein kinase I" Q14012 3 9757342-9769992 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Differentiation, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.5;blood: 59.4" "Cell type enhanced" "Detected in many" 6 "Hofbauer cells: 76.7;Sertoli cells: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "eosinophil: 59.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 59.4" "Cell line enriched" "Detected in many" 4 "HMC-1: 94.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031904, HPA051409" Approved Approved Cytosol NA NA 550000 Cytosol "CAB031904: AB_630964, HPA051409: AB_2681473" "unprognostic (4.43e-2)" "unprognostic (3.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (1.11e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.53e-2)" "unprognostic (3.32e-1)" "unprognostic (9.74e-2)" "unprognostic (1.37e-3)" "unprognostic (2.17e-1)" "unprognostic (1.14e-3)" "unprognostic (7.76e-2)" "unprognostic (1.72e-1)" "unprognostic (3.67e-2)" "unprognostic (3.01e-1)" 27.1 60.5 28.0 11.7 26.0 3.5 34.1 12.4 31.2 9.5 10.7 4.4 5.8 6.8 12.6 10.5 7.1 12.6 8.9 10.2 21.4 14.0 13.1 20.7 9.2 10.4 10.3 19.9 21.5 4.5 7.4 7.9 5.1 10.1 18.6 8.1 6.8 5.1 15.1 4.7 3.3 8.3 18.4 7.2 7.1 8.1 13.4 5.6 0.6 7.0 3.7 10.4 9.5 10.3 0.0 3.2 59.4 9.2 0.7 0.4 0.9 0.1 3.7 3.0 0.0 15.4 5.7 7.5 8.8 4.9 10.1 9.6 5.4 0.6 0.2 2.0 5.9 1.5 0.6 0.0 1.1 6.3 0.1 21.6 11.9 7.0 7.5 8.6 1.0 94.0 6.0 0.9 14.2 1.5 8.3 8.4 0.2 1.5 0.2 3.7 2.2 0.0 8.7 2.1 0.1 5.8 0.0 0.1 0.2 6.0 0.6 1.0 3.8 1.5 0.1 0.8 1.3 0.9 15.2 4.4 4.6 5.7 6.5 11.0 0.1 0.0 0.2 9.8 3.3 0.6 3.3 4.8 59.4 0.0 9.2 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.2 0.7 9.2 0.1 0.4 0.9 28.0 26.0 12.4 31.2 21.4 14.0 10.3 19.9 10.1 5.6 0.0 1.9 6.4 17.8 4.4 8.1 0.0 10.2 1.4 2.3 10.4 2.0 0.4 8.3 13.1 1.5 22.7 2.0 0.0 3.6 1.0 11.6 14.9 31.0 21.2 76.7 0.0 5.8 17.8 40.5 3.9 33.4 50.8 5.0 19.0 1.3 30.9 6.0 3.5 42.5 35.3 8.0 58.2 35.0 1.1 1.1 3.3 0.7 7.5 5.5 10.8 CAMK1D CKLiK ENSG00000183049 "Calcium/calmodulin dependent protein kinase ID" Q8IU85 10 12349482-12835545 "Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Bipolar cells: 148.3;Cone photoreceptor cells: 369.1;Rod photoreceptor cells: 206.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 31.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 31.8" "Cell line enhanced" "Detected in many" "HDLM-2: 47.7;U-266/70: 22.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007266 Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA007266: AB_1078389" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-3)" "unprognostic (4.23e-1)" "unprognostic (2.32e-2)" "unprognostic (6.90e-3)" "prognostic favorable (1.67e-4)" "unprognostic (1.06e-1)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (7.40e-2)" "unprognostic (1.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.65e-1)" "unprognostic (4.66e-2)" "unprognostic (2.56e-3)" 5.1 5.3 20.9 10.5 22.1 6.6 4.0 23.4 33.5 8.3 11.5 4.6 10.0 3.8 3.3 3.3 8.7 4.3 6.8 13.8 18.6 7.2 2.2 11.5 7.6 9.3 5.8 17.8 2.6 17.0 1.3 2.5 3.2 5.0 4.9 12.9 11.9 4.5 15.4 1.7 18.5 5.5 5.6 4.9 10.5 3.4 6.2 6.8 20.8 13.6 2.9 12.5 8.1 7.0 7.1 4.2 31.8 3.7 1.4 2.3 1.3 0.1 2.6 3.0 0.2 1.8 0.6 0.2 0.4 0.9 0.6 0.9 3.6 2.0 1.4 0.3 0.2 1.5 1.4 3.6 0.5 0.5 47.7 1.8 5.7 8.5 0.2 0.5 0.1 5.2 0.1 2.3 1.2 0.1 6.4 0.3 3.1 0.1 0.2 0.7 3.0 11.1 2.3 2.0 0.0 1.2 8.5 1.6 2.6 0.1 2.8 4.6 2.1 5.7 2.1 0.0 0.4 1.5 1.4 0.1 2.5 3.7 7.9 1.7 22.0 6.9 4.8 3.7 3.7 0.0 8.3 2.2 31.8 1.8 3.1 1.9 5.6 1.6 2.3 4.2 7.1 1.9 1.3 13.9 1.4 3.7 1.4 0.5 1.3 20.9 22.1 23.4 33.5 18.6 7.2 5.8 17.8 5.0 6.8 3.0 28.0 44.7 7.2 20.4 148.3 10.3 15.3 20.1 29.6 1.8 369.1 0.2 0.0 7.8 7.2 8.3 8.8 0.0 19.1 0.7 22.0 3.5 22.0 11.0 15.1 42.9 15.4 11.1 39.3 7.4 21.9 37.1 3.3 24.4 26.1 18.0 9.6 35.1 57.3 0.5 206.3 25.8 9.2 3.9 9.6 36.0 0.2 10.2 29.3 16.3 CAMK1G "CLICKIII, dJ272L16.1, VWS1" ENSG00000008118 "Calcium/calmodulin dependent protein kinase IG" Q96NX5 1 209583717-209613938 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 34.4;ovary: 29.2" "Group enriched" "Detected in some" 6 "Peritubular cells: 6.3;Sertoli cells: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.6;hTERT-RPE1: 6.9;SK-MEL-30: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (5.17e-2)" "unprognostic (9.64e-2)" "unprognostic (1.73e-1)" "unprognostic (1.49e-3)" "unprognostic (2.56e-2)" "unprognostic (1.93e-1)" "unprognostic (6.79e-2)" "unprognostic (3.98e-1)" "unprognostic (3.59e-3)" "unprognostic (8.55e-3)" "unprognostic (3.17e-2)" "unprognostic (1.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.27e-1)" "unprognostic (9.10e-2)" "unprognostic (3.43e-2)" 0.7 3.5 7.5 0.9 34.4 1.0 0.7 1.3 27.8 1.1 0.8 0.7 1.2 0.8 1.8 6.1 0.6 0.9 1.5 0.6 10.9 9.2 6.9 0.9 1.2 0.8 3.6 17.7 29.2 1.3 0.6 2.0 2.8 3.9 4.6 0.8 0.6 0.6 7.4 0.6 0.6 0.8 2.3 0.9 6.1 0.7 1.4 2.7 0.0 0.7 0.0 0.8 1.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 1.9 0.3 0.8 0.2 0.0 0.1 0.0 0.0 0.7 0.1 0.2 0.0 0.0 1.2 0.6 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 11.6 0.0 6.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 1.6 0.0 0.0 0.2 2.0 0.2 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 34.4 1.3 27.8 10.9 9.2 3.6 17.7 3.9 2.7 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 6.3 0.3 0.0 6.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 CAMK2A "CAMKA, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290291 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "brain: 105.7;skeletal muscle: 50.1" "Cell type enhanced" "Detected in some" 20 "Basal keratinocytes: 3.1;Cardiomyocytes: 11.0;Fibroblasts: 2.8;Melanocytes: 3.3" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Group enriched" "Detected in all" 6 "amygdala: 60.7;basal ganglia: 50.6;cerebral cortex: 99.6;hippocampal formation: 74.6;olfactory region: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.7;SCLC-21H: 9.6;SuSa: 2.6;U-87 MG: 8.1" "Group enriched" "Detected in all" 4 "amygdala: 1311.6;basal ganglia: 698.1;cerebral cortex: 1576.4;hippocampal formation: 1569.1" "Low region specificity" "Detected in all" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 21000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" 1.3 1.7 60.7 1.3 50.6 1.3 1.1 1.4 105.7 1.8 1.3 3.7 0.0 1.2 2.1 1.4 1.9 1.7 1.3 3.7 74.6 10.5 1.6 1.2 1.5 1.2 5.1 39.8 1.3 1.1 1.1 0.4 1.3 2.4 1.6 1.3 0.0 1.2 1.4 50.1 1.6 1.3 2.5 1.7 1.2 1.3 1.2 2.3 0.0 1.2 0.0 1.1 1.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.6 0.0 0.5 1.3 0.8 0.7 0.0 0.1 0.0 0.2 0.6 0.1 2.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.2 0.5 0.2 1.7 0.0 1.1 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.0 9.6 0.0 0.1 0.2 0.3 2.6 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.1 0.0 8.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 60.7 50.6 1.4 99.6 74.6 10.5 5.1 39.8 2.4 2.3 0.0 0.0 0.0 0.0 3.1 0.1 11.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.0 0.4 0.8 0.0 0.0 1.1 0.0 0.2 1.3 0.2 0.0 0.0 0.0 CAMK2B "CAM2, CAMK2, CAMKB" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;heart muscle: 39.2;skeletal muscle: 70.7" "Cell type enriched" "Detected in many" 11 "Bipolar cells: 838.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 42.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA 680000 "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 1.4 8.1 20.6 1.4 46.7 1.2 2.0 60.1 81.9 1.2 1.4 4.0 0.7 1.7 1.3 18.8 2.0 1.8 1.2 39.2 36.5 18.0 1.7 3.5 1.2 1.8 10.3 21.3 1.1 3.3 5.6 9.9 1.1 13.4 3.0 1.4 2.7 1.8 2.2 70.7 1.8 1.6 1.2 4.1 1.3 2.4 2.3 4.8 0.0 7.7 2.4 2.0 1.1 0.0 1.3 1.0 3.2 1.2 3.2 1.2 0.8 0.0 0.3 0.2 0.3 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.9 0.2 0.1 0.1 0.2 0.8 0.0 1.1 2.4 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.0 5.3 0.0 0.2 0.1 0.0 2.4 0.1 0.9 0.1 0.0 0.0 42.0 2.2 0.2 0.0 0.0 0.1 1.9 0.2 0.2 0.2 0.4 0.2 0.0 0.5 0.4 0.1 0.2 0.0 0.2 3.2 0.7 1.0 0.8 0.9 1.2 1.1 1.0 0.5 0.5 1.3 1.2 1.1 2.0 3.2 1.2 1.0 0.9 0.8 20.6 46.7 60.1 42.4 36.5 18.0 10.3 21.3 13.4 4.8 0.0 0.0 0.0 27.8 1.0 838.1 74.9 2.5 0.0 0.0 0.0 43.2 0.0 8.3 0.0 0.8 0.6 0.0 0.0 0.0 0.1 0.4 2.6 4.6 4.4 0.2 57.2 39.0 0.0 1.2 2.1 1.7 0.0 1.7 0.0 0.0 14.1 0.1 0.0 0.0 0.8 46.7 0.0 0.9 0.0 1.7 0.4 0.2 0.0 0.0 0.7 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cardiomyocytes: 243.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 140000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 22.8 12.9 47.7 18.3 13.0 2.8 23.5 50.2 30.6 11.0 18.2 7.4 28.6 13.6 11.6 9.4 15.6 9.6 14.8 77.1 17.9 21.4 9.6 17.6 14.7 17.5 14.0 23.8 12.9 7.4 33.7 7.0 9.3 12.5 16.3 19.0 9.9 9.4 48.3 48.5 10.8 19.2 26.2 16.0 8.4 17.6 9.4 8.5 11.2 11.6 9.8 14.5 21.5 22.6 18.5 11.2 0.6 8.8 6.4 9.7 5.2 1.0 14.5 16.1 5.4 35.2 67.4 5.7 34.1 22.8 13.4 11.6 9.8 4.1 20.9 5.0 23.7 17.0 0.5 10.0 5.3 13.7 8.0 2.5 0.0 5.3 11.2 17.9 0.0 0.0 43.0 7.3 10.4 25.8 21.3 11.9 2.6 0.8 9.3 25.3 3.9 2.1 0.8 2.3 13.9 5.4 4.0 18.9 0.1 13.7 9.9 4.3 4.4 4.6 6.9 4.6 14.0 0.1 5.6 7.1 35.5 8.4 15.1 6.7 7.3 3.6 17.9 18.3 1.3 16.7 0.0 8.8 0.0 5.1 5.1 9.7 8.0 5.0 5.6 11.2 18.5 5.8 4.9 0.6 6.4 1.7 0.0 9.3 5.2 47.7 13.0 50.2 25.6 17.9 21.4 14.0 23.8 12.5 8.5 38.7 29.9 22.6 16.0 16.4 72.0 243.3 58.6 20.1 28.4 27.9 82.5 0.4 5.0 6.4 2.9 29.8 57.0 0.0 17.5 0.4 34.7 31.3 9.3 49.4 15.8 68.3 99.5 19.6 16.8 4.5 18.7 21.0 5.0 2.8 82.1 41.3 11.4 45.6 18.7 17.7 71.5 6.5 33.3 2.9 4.4 27.9 0.9 17.5 41.1 16.3 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.0" "Cell type enhanced" "Detected in many" 6 "Cone photoreceptor cells: 94.2;Cytotrophoblasts: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.8" "Cell line enhanced" "Detected in all" "PC-3: 46.3;SK-BR-3: 58.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 170000 "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: AB_2677065, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 9.1 8.8 27.4 9.4 20.7 17.4 6.8 22.2 53.8 9.0 37.3 13.3 9.7 19.7 20.1 9.1 20.6 13.2 10.6 6.7 22.8 24.4 11.6 5.9 10.7 8.9 26.8 31.2 6.4 5.7 8.0 6.0 15.8 38.6 18.5 15.5 8.5 12.4 29.8 73.0 9.1 18.1 29.6 29.8 11.0 14.2 3.8 13.4 4.4 6.4 7.6 8.7 26.5 10.8 4.2 7.1 39.8 5.6 9.8 9.2 5.0 11.1 8.0 7.3 13.9 5.3 8.7 8.6 7.6 13.2 10.6 8.7 12.5 12.0 8.2 8.1 9.8 4.1 17.4 5.7 6.5 8.4 7.5 6.8 5.6 6.2 5.6 2.6 7.6 9.5 4.6 5.9 10.5 7.3 16.3 9.0 10.6 6.1 12.4 5.8 7.8 12.7 11.4 5.3 6.8 46.3 11.6 7.6 4.3 5.5 16.2 3.8 8.8 4.4 58.3 3.7 5.6 10.9 4.8 11.0 7.9 12.7 4.2 10.3 3.8 4.5 7.7 8.4 21.9 2.8 8.5 5.6 39.8 7.5 2.3 9.2 4.2 8.4 8.0 7.1 3.9 8.1 7.9 36.4 9.8 4.0 2.4 8.1 5.0 27.4 20.7 22.2 53.8 22.8 24.4 26.8 31.2 38.6 13.4 14.9 9.4 11.5 7.6 8.4 55.8 6.1 15.3 6.7 9.1 7.0 94.2 130.5 11.6 10.6 1.9 18.0 50.5 0.0 17.2 36.6 11.5 7.3 16.1 7.8 22.8 25.4 23.0 12.3 13.6 2.3 11.8 10.5 11.8 5.4 20.0 16.3 16.9 51.8 17.7 27.0 74.1 45.3 50.6 0.5 10.6 11.0 67.9 22.4 26.2 10.7 CAMK4 CaMK-GR ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.9;lymphoid tissue: 71.7" "Cell type enhanced" "Detected in many" 27 "Bipolar cells: 47.8;Early spermatids: 236.0;Late spermatids: 80.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 14.1;memory CD4 T-cell: 10.3;memory CD8 T-cell: 7.8;naive CD4 T-cell: 19.8;naive CD8 T-cell: 10.9;T-reg: 11.3" "Lineage enriched" "Detected in single" 26 "T-cells: 19.8" "Cell line enhanced" "Detected in many" "HDLM-2: 39.4;JURKAT: 27.3;MOLT-4: 12.0;SH-SY5Y: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 1.1 6.5 9.5 6.4 34.2 4.6 1.0 48.9 16.5 1.8 2.3 1.0 0.0 2.4 1.3 0.8 1.4 0.9 2.7 0.9 5.9 3.2 1.4 2.5 1.9 12.0 2.3 6.8 1.4 0.9 0.3 1.3 0.6 3.4 5.8 2.5 0.1 1.7 2.6 0.8 0.9 3.8 1.5 2.0 4.2 2.6 13.8 6.6 71.7 1.0 0.0 8.1 2.8 1.1 0.7 0.0 0.4 0.0 0.6 19.8 3.4 0.0 0.0 1.4 0.9 0.3 1.1 0.0 0.3 3.0 3.6 3.6 0.0 0.0 0.0 1.9 0.1 2.4 0.1 3.0 0.3 2.6 39.4 2.4 0.5 1.3 0.0 0.1 0.2 0.1 0.1 0.0 7.6 0.8 2.2 0.6 27.3 0.0 1.4 0.2 0.0 12.0 0.0 1.8 0.0 0.1 1.8 2.3 0.1 1.3 0.0 8.6 15.4 0.5 0.0 2.6 0.1 0.0 0.2 0.0 7.5 4.4 0.0 6.6 1.2 0.1 0.0 3.6 0.0 2.8 0.0 0.0 0.0 2.8 0.0 14.1 0.7 10.3 7.8 0.0 0.2 19.8 10.9 0.4 0.6 0.0 0.0 11.3 3.4 9.5 34.2 48.9 15.1 5.9 3.2 2.3 6.8 3.4 6.6 0.0 0.6 4.2 0.2 1.0 47.8 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 236.0 0.7 0.0 0.0 0.0 0.1 1.6 0.4 4.6 0.2 0.2 0.0 0.0 0.6 1.0 80.4 3.7 1.1 0.0 0.0 0.1 2.1 0.8 0.0 1.4 0.0 4.1 0.0 4.5 3.2 6.1 0.9 0.0 29.9 0.0 0.3 CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.9;salivary gland: 27.1" "Cell type enhanced" "Detected in many" 9 "Bipolar cells: 36.4;Rod photoreceptor cells: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 18.2;U-87 MG: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009111, HPA028062" Approved Supported Cytosol No No Cytosol "CAB009111: AB_2068406, HPA028062: AB_1845954" "unprognostic (1.39e-2)" "unprognostic (2.13e-1)" "unprognostic (8.66e-3)" "unprognostic (4.40e-3)" "unprognostic (2.94e-3)" "unprognostic (4.79e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-3)" "unprognostic (8.23e-2)" "unprognostic (1.03e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (7.19e-2)" "unprognostic (8.70e-2)" "unprognostic (8.36e-2)" "unprognostic (3.10e-1)" 4.3 10.2 15.3 5.1 21.4 3.7 4.7 23.2 38.9 4.1 3.2 2.2 4.0 3.1 7.5 5.2 4.2 3.7 3.8 5.7 13.8 6.8 1.5 1.0 4.0 2.5 5.5 16.0 6.0 7.5 5.0 10.1 2.3 11.2 3.3 3.1 2.5 27.1 11.2 2.2 7.8 3.7 6.2 2.2 4.3 2.9 6.1 5.0 1.7 7.2 2.3 2.5 5.6 4.9 0.1 1.6 5.6 4.1 0.0 1.0 1.1 4.9 8.5 0.9 4.3 3.1 5.5 0.3 3.4 3.7 3.3 1.5 3.1 1.5 3.0 3.7 6.6 3.4 14.7 2.3 4.2 2.0 0.1 7.8 3.4 18.2 1.1 3.1 0.5 2.7 4.2 3.6 6.2 2.1 2.9 1.5 4.4 2.6 0.1 1.6 1.3 4.1 1.9 1.0 7.2 8.1 2.1 3.7 3.4 3.5 3.1 5.0 2.8 1.3 10.2 2.2 0.5 3.9 1.1 2.0 5.7 7.7 7.3 2.8 0.4 0.2 0.1 20.8 2.9 0.7 0.0 1.8 3.6 0.6 3.9 1.0 0.0 0.6 0.5 1.6 0.1 0.6 0.3 5.6 0.0 4.1 0.8 0.0 1.1 15.3 21.4 23.2 38.9 13.8 6.8 5.5 16.0 11.2 5.0 6.0 15.1 8.5 1.9 3.3 36.4 5.7 0.0 1.4 5.7 1.8 15.7 0.2 0.0 0.4 0.0 4.4 0.5 0.0 1.4 0.1 4.5 1.4 16.2 0.2 3.8 7.9 4.1 3.1 1.9 0.4 1.1 3.6 8.5 0.0 1.4 3.8 0.8 0.0 1.1 0.0 24.1 0.0 2.0 0.1 1.4 4.6 0.2 0.7 2.3 0.8 CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237691-121298308 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 125.5" "Cell type enhanced" "Detected in many" 5 "Horizontal cells: 58.8;Late spermatids: 64.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 125.5" "Group enriched" "Detected in many" 5 "classical monocyte: 14.2;eosinophil: 26.1;intermediate monocyte: 19.4;myeloid DC: 7.2;neutrophil: 17.2;non-classical monocyte: 16.5" "Group enriched" "Detected in all" 5 "dendritic cells: 7.2;granulocytes: 26.1;monocytes: 19.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol NA NA Cytosol "HPA017389: AB_1845956, HPA063713: " "unprognostic (5.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-3)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" 11.7 6.5 19.7 7.8 30.2 13.8 8.8 125.5 45.5 9.0 9.5 7.1 2.6 12.8 8.6 5.3 8.3 11.8 6.3 6.9 11.2 5.1 7.1 8.9 9.6 6.9 6.2 17.3 10.5 5.8 6.4 4.1 7.5 9.1 12.2 9.7 6.2 7.5 13.2 5.1 9.1 13.2 10.3 6.2 14.1 7.6 3.6 5.8 5.2 6.1 4.5 7.2 7.2 7.4 2.2 7.2 26.1 19.4 3.6 2.2 6.3 12.5 9.4 7.0 13.5 21.1 19.7 10.7 10.4 11.0 8.5 7.8 9.8 5.4 19.4 8.7 21.0 6.0 10.4 8.6 11.2 6.7 13.3 16.9 9.6 6.3 9.6 14.3 21.9 9.2 12.7 16.6 8.0 18.2 11.5 19.9 14.8 11.1 10.5 8.2 12.1 24.3 18.0 5.1 10.5 10.7 15.8 8.2 17.2 8.2 14.0 26.9 10.8 13.6 7.3 8.6 5.9 18.2 26.8 14.5 7.0 5.7 5.9 5.7 40.3 23.9 14.7 13.1 15.4 6.9 0.7 14.2 26.1 2.1 19.4 2.2 2.2 1.7 1.9 7.2 1.2 1.5 1.7 17.2 3.6 16.5 1.6 1.3 6.3 19.7 30.2 125.5 45.5 11.2 5.1 6.2 17.3 9.1 5.8 8.9 3.5 4.1 5.1 7.0 21.6 7.0 20.4 8.1 6.8 8.7 2.0 7.4 3.3 8.7 15.7 17.5 18.2 0.0 9.0 6.7 12.5 10.8 5.8 18.3 7.1 58.8 33.0 12.9 13.9 64.8 19.0 13.7 8.5 15.4 15.9 5.1 7.5 11.5 29.7 8.4 6.4 19.4 21.3 0.7 2.4 5.3 2.9 7.1 15.6 5.8 CAMKV "MGC8407, VACAMKL" ENSG00000164076 "CaM kinase like vesicle associated" Q8NCB2 3 49857988-49870222 "Enzymes, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "brain: 77.2" "Cell type enhanced" "Detected in some" 14 "Bipolar cells: 2.3;Cone photoreceptor cells: 2.0;Early spermatids: 4.6;Horizontal cells: 3.2;Late spermatids: 6.5" "Group enriched" "Detected in some" 11 "glioma: 4.0;testis cancer: 5.2" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 12 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cell line enhanced" "Detected in some" "AF22: 5.3;HAP1: 7.0;NTERA-2: 25.2;RPMI-8226: 4.8;SCLC-21H: 8.6;SH-SY5Y: 5.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007656, CAB034931" Enhanced Supported Approved "Nucleoplasm,Cytokinetic bridge" NA NA Nucleoplasm "Cytokinetic bridge" "CAB034931: AB_2068550, HPA007656: AB_1078391" "unprognostic (9.47e-4)" "unprognostic (5.65e-3)" "unprognostic (1.42e-1)" "unprognostic (2.70e-7)" "unprognostic (2.76e-1)" "unprognostic (7.95e-4)" "unprognostic (3.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.48e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (8.11e-2)" "unprognostic (1.00e-3)" "unprognostic (7.61e-2)" "unprognostic (9.51e-2)" "unprognostic (1.67e-3)" 1.2 2.1 20.7 1.2 77.2 1.2 1.2 0.5 62.8 1.2 1.2 1.7 0.0 1.2 1.2 1.2 1.2 1.2 1.2 1.2 33.4 11.7 1.2 1.2 1.2 1.2 3.3 23.5 1.2 1.2 1.2 1.8 1.2 2.1 1.2 1.2 0.0 1.2 1.2 1.2 1.3 1.2 1.2 1.9 1.2 1.3 2.1 6.0 0.0 1.2 0.0 1.2 1.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 5.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.1 0.7 0.1 25.2 0.0 0.1 0.8 0.0 4.8 0.0 0.0 8.6 5.5 0.0 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 20.7 77.2 0.5 34.0 33.4 11.7 3.3 23.5 2.1 6.0 0.0 0.0 0.0 0.0 0.2 2.3 0.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.2 1.2 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.1 0.2 0.0 0.1 0.0 CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923645 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 5 "basophil: 26.3" "Lineage enriched" "Detected in many" 11 "granulocytes: 26.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" 9.1 15.9 13.9 18.8 12.7 9.8 13.2 14.2 15.7 11.1 22.1 20.0 7.1 27.1 12.2 13.7 17.2 9.9 16.0 7.0 12.1 12.8 14.6 10.8 10.3 13.6 16.3 8.5 13.9 14.2 11.1 9.8 13.4 11.9 10.7 23.8 10.4 15.9 7.7 5.8 12.8 32.9 12.1 10.1 9.6 16.2 2.9 14.3 30.9 9.3 8.1 14.0 11.8 13.1 0.6 0.3 26.3 0.8 2.4 2.3 0.3 10.9 14.0 13.4 8.0 9.1 7.4 4.3 9.6 8.0 5.6 5.2 30.1 17.9 0.1 4.9 11.9 10.2 22.0 14.7 9.8 9.4 9.7 8.2 0.0 12.6 10.6 9.4 1.7 1.5 8.4 26.9 10.7 13.7 11.3 4.6 6.4 0.8 8.5 12.2 12.8 3.1 0.7 12.3 15.8 9.1 5.1 33.0 5.2 12.7 23.8 12.3 6.5 18.0 7.2 5.5 22.6 7.7 0.3 5.3 10.5 10.7 9.0 5.3 3.3 2.1 3.7 10.3 1.2 6.7 26.3 0.8 4.8 0.5 0.7 0.5 0.4 0.6 0.8 0.2 0.6 0.7 0.7 1.1 2.4 0.4 0.3 2.3 0.3 13.9 12.7 14.2 14.2 12.1 12.8 16.3 8.5 11.9 14.3 11.9 14.8 0.9 33.3 29.0 40.5 6.5 10.2 20.1 14.8 7.0 21.6 1.6 43.1 13.2 0.8 10.8 22.7 0.0 12.7 0.7 17.5 19.6 0.0 13.0 16.2 47.7 13.3 4.9 3.5 0.2 9.2 6.8 10.1 0.0 30.6 11.9 17.9 28.1 8.9 17.0 26.0 19.4 14.4 1.6 1.9 28.4 1.4 12.5 36.5 26.9 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Horizontal cells: 211.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" NA NA "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: AB_2686374" "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 17.2 15.2 19.1 8.6 21.1 3.9 14.0 29.2 20.4 21.1 19.3 16.4 13.1 16.9 15.8 9.9 12.3 12.9 16.6 14.1 21.7 17.7 20.8 17.0 11.7 3.5 20.0 16.3 17.4 15.1 29.3 29.6 14.8 19.3 21.1 12.4 11.0 8.4 18.5 11.9 7.6 17.2 27.6 16.6 8.8 25.2 26.7 19.9 0.7 9.8 7.3 2.5 23.4 23.1 0.1 0.7 2.0 0.1 0.0 0.1 0.0 9.5 9.0 9.7 4.5 9.7 12.0 3.4 11.0 15.6 7.6 8.0 7.3 21.8 0.0 11.8 18.2 5.7 4.4 7.1 6.1 9.3 0.0 5.7 7.4 10.8 2.8 11.0 5.9 3.3 8.4 7.9 12.3 12.4 9.5 25.3 5.9 18.7 0.0 12.3 2.6 0.1 1.0 7.9 12.4 8.7 0.0 16.3 0.0 12.2 18.5 7.0 10.2 18.6 7.8 10.9 6.2 10.1 0.3 25.5 13.9 7.3 15.9 14.5 0.0 0.0 0.0 18.5 0.0 18.6 2.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 19.1 21.1 29.2 20.4 21.7 17.7 20.0 16.3 19.3 19.9 38.7 29.4 1.4 19.9 10.4 96.7 50.6 25.5 21.4 35.2 41.8 111.9 5.2 11.6 22.3 90.9 47.3 45.2 23.3 35.4 6.1 27.8 25.0 6.9 24.5 3.2 211.4 25.3 42.4 7.1 98.3 40.9 6.8 15.1 9.0 24.1 34.1 46.5 54.5 80.2 32.9 64.0 77.6 45.3 40.8 51.3 6.9 1.1 1.3 26.4 26.8 CDC42BPB "KIAA1124, MRCKB" ENSG00000198752 "CDC42 binding protein kinase beta" Q9Y5S2 14 102932379-103057462 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022821 Approved NA NA 12000 "HPA022821: AB_1846376" "unprognostic (6.73e-2)" "unprognostic (2.19e-2)" "unprognostic (6.99e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "unprognostic (3.46e-2)" "unprognostic (2.28e-1)" "prognostic favorable (8.67e-10)" "unprognostic (2.11e-1)" "unprognostic (1.86e-1)" "unprognostic (8.59e-2)" "unprognostic (7.56e-2)" 32.2 22.7 33.1 14.8 33.2 3.1 19.8 30.3 42.1 26.7 21.8 42.3 21.5 26.0 27.0 18.7 28.3 26.0 28.1 30.7 31.4 25.5 23.7 20.1 26.4 7.9 31.2 28.4 29.7 28.8 32.5 25.9 25.6 27.0 25.1 18.2 23.7 23.0 28.8 17.0 23.8 29.6 28.7 24.3 18.3 25.5 21.8 31.0 2.1 26.3 15.9 12.4 25.2 32.6 0.9 0.2 0.0 2.0 0.0 0.4 0.1 13.3 26.7 17.2 12.6 19.2 22.0 17.4 15.3 16.2 16.3 15.0 9.1 15.8 0.0 16.8 29.8 12.4 17.0 17.7 18.3 17.3 16.3 8.0 7.3 21.6 9.1 20.9 0.0 7.9 19.0 18.9 16.7 16.0 17.2 31.5 3.1 5.9 3.8 15.6 28.0 0.1 1.7 8.2 20.9 22.1 0.0 14.5 0.3 20.8 26.3 12.5 13.7 27.2 10.3 11.5 19.1 15.8 4.7 40.1 15.7 10.5 34.5 14.2 4.9 5.3 3.9 17.6 1.6 15.1 0.0 1.4 0.0 0.0 2.0 0.0 0.9 0.4 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 33.1 33.2 30.3 42.1 31.4 25.5 31.2 28.4 27.0 31.0 53.6 30.2 6.9 10.7 12.9 45.3 25.4 28.1 33.5 33.0 52.4 31.4 10.5 3.3 26.7 14.0 32.3 28.4 0.0 19.0 8.9 18.2 22.0 12.7 16.3 11.2 54.0 24.2 30.1 12.0 4.9 30.0 12.3 11.8 10.0 14.9 28.0 31.1 17.3 51.9 13.5 42.2 6.5 19.6 13.7 16.0 15.9 14.1 1.0 20.9 28.8 CDC42BPG "DMPK2, HSMDPKIN, kappa-200, MRCKgamma" ENSG00000171219 "CDC42 binding protein kinase gamma" Q6DT37 11 64823387-64844569 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Club cells: 12.5;Enterocytes: 10.6;Paneth cells: 14.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 9 "cerebellum: 19.4" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 19.5;HaCaT: 14.6;MCF7: 19.7;RT4: 12.0;SK-BR-3: 12.1;T-47d: 11.9" "Region enriched" "Detected in single" 4 "cerebellum: 5.9" "Low region specificity" "Detected in single" "HPA027382, HPA061836" Enhanced Supported Cytosol NA NA Cytosol "HPA027382: AB_1846378, HPA061836: AB_2684622" "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (6.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" "unprognostic (4.68e-1)" "unprognostic (5.27e-2)" "unprognostic (3.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "prognostic favorable (5.99e-13)" "unprognostic (2.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-2)" "unprognostic (3.99e-3)" 0.5 2.7 0.8 2.1 0.5 1.1 3.5 19.4 0.8 2.9 9.1 0.8 6.3 8.2 1.0 8.0 14.3 2.9 10.5 0.5 0.7 0.0 3.5 0.5 4.2 0.7 0.5 0.5 1.5 7.9 7.0 6.5 13.0 2.0 4.4 3.4 1.0 14.3 7.6 0.5 22.4 19.7 1.6 0.8 0.8 8.5 2.5 0.7 1.8 3.9 8.1 7.7 5.4 6.3 0.4 0.0 0.0 0.0 0.2 1.0 0.1 5.6 0.8 0.5 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 7.6 4.8 0.1 2.8 0.0 0.2 14.6 0.9 5.7 0.0 0.2 2.2 0.4 3.1 2.4 0.0 0.1 1.4 0.0 7.2 0.1 0.1 0.0 0.0 2.3 3.8 0.0 0.0 19.7 0.1 1.0 1.8 5.3 0.8 0.8 0.3 2.7 3.4 12.0 10.4 0.5 1.8 12.1 0.3 2.9 11.9 0.2 0.0 0.0 2.1 0.0 0.0 1.4 1.3 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.8 0.5 19.4 0.8 0.7 0.0 0.5 0.5 2.0 0.7 8.9 6.4 0.0 2.3 5.8 0.0 1.6 2.5 6.7 12.5 1.8 0.0 4.8 0.0 1.7 0.5 0.0 10.6 0.0 5.3 4.1 0.6 2.1 1.1 0.0 0.9 0.0 3.5 0.0 0.0 0.4 0.0 0.2 0.0 1.8 3.3 0.9 2.8 14.0 0.0 0.3 0.0 0.0 0.5 1.7 1.1 7.0 5.6 0.0 3.8 2.0 CDC7 "CDC7L1, HsCdc7, Hsk1, huCdc7" ENSG00000097046 "Cell division cycle 7" O00311 1 91500893-91525764 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 28.3;Spermatocytes: 28.4;Spermatogonia: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002669, HPA035831" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "CAB002669: , HPA035831: AB_2674807" "unprognostic (6.84e-2)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (7.02e-3)" "unprognostic (5.57e-2)" "unprognostic (3.57e-3)" "prognostic unfavorable (3.15e-6)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (1.36e-3)" "unprognostic (2.04e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.89e-15)" "unprognostic (9.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.09e-1)" "unprognostic (5.39e-2)" 2.5 3.7 5.7 7.6 8.9 15.4 4.3 19.4 10.3 2.5 4.2 1.4 0.9 4.2 2.8 2.6 4.7 1.7 2.6 1.9 6.8 5.2 3.6 2.3 5.1 11.7 4.0 4.7 3.7 2.4 2.2 12.3 7.9 5.2 2.7 6.8 2.3 2.5 2.3 1.0 6.8 4.9 3.3 5.9 15.1 2.6 21.2 4.7 18.7 2.5 4.5 12.0 4.2 3.0 1.6 3.5 0.1 1.6 2.4 6.5 2.1 14.2 4.2 27.6 7.8 0.6 3.7 8.8 5.4 4.3 10.7 11.7 8.9 5.1 9.9 7.6 3.4 9.3 6.2 18.1 6.1 14.8 16.4 15.5 15.0 12.2 4.1 1.0 16.3 5.5 1.9 1.8 9.8 5.6 1.9 4.1 13.9 19.8 14.5 7.3 5.2 14.0 14.6 22.9 7.8 10.1 17.3 22.9 6.3 4.6 10.7 21.9 8.6 17.1 4.7 9.6 7.1 4.4 8.0 3.4 12.1 10.7 9.4 8.1 5.3 6.7 26.5 4.3 15.9 4.4 0.0 1.6 0.0 5.9 1.2 5.2 1.5 4.5 5.6 3.5 1.6 2.5 5.1 0.1 2.4 0.3 2.1 6.5 2.1 5.7 8.9 19.4 10.3 6.8 5.2 4.0 4.7 5.2 4.7 0.0 0.6 2.2 1.1 5.3 7.6 1.3 0.0 1.4 1.2 1.8 0.0 5.3 3.3 1.1 28.3 2.8 0.2 0.0 2.2 5.1 4.6 0.7 4.6 0.0 2.2 3.2 0.0 3.1 1.8 12.9 0.9 1.0 3.3 1.0 1.3 1.3 1.0 1.1 0.7 0.1 4.7 6.5 3.1 28.4 20.6 3.1 1.8 5.1 2.9 0.9 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 88.4" "Cell type enhanced" "Detected in many" 18 "Erythroid cells: 280.4;Extravillous trophoblasts: 116.8;Spermatocytes: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cell: 6.1;T-reg: 5.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;NK-cells: 6.1;T-cells: 5.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA003387, CAB003799" Enhanced Supported Nucleoplasm,Cytosol NA Yes Cytosol Nucleoplasm "CAB003799: AB_344898, HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favorable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavorable (1.10e-6)" "prognostic unfavorable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 4.1 2.2 0.8 17.8 2.4 17.8 4.4 0.7 1.6 4.2 6.5 1.1 3.4 6.1 2.9 4.8 19.0 1.5 2.4 2.3 0.9 0.7 3.1 1.7 5.7 15.1 1.7 0.6 2.2 1.0 0.5 4.4 13.3 1.2 1.5 8.3 1.0 3.8 2.9 1.0 4.9 8.3 2.7 2.5 8.3 5.0 13.8 1.2 88.4 1.8 16.7 20.1 3.2 6.9 0.9 1.7 0.0 0.2 6.1 5.7 1.8 48.9 18.6 49.6 19.6 3.2 5.0 20.4 37.0 27.0 45.2 43.6 43.6 43.3 44.9 14.4 10.1 16.6 30.5 33.7 21.5 47.1 31.9 24.6 23.5 18.4 25.3 0.6 36.0 24.3 0.9 2.1 29.2 28.5 10.3 27.1 29.6 35.9 55.3 50.2 13.0 45.3 25.9 21.8 29.6 39.3 39.4 46.2 22.0 17.2 16.3 23.3 20.4 24.9 37.8 19.2 28.1 40.8 22.1 11.1 19.3 41.2 20.3 50.6 21.7 34.8 40.5 16.6 40.4 23.9 0.0 0.0 0.0 0.5 0.2 0.5 0.9 1.5 2.7 0.5 0.5 0.5 1.5 0.0 6.1 0.2 1.7 5.7 1.8 0.8 2.4 0.7 1.6 0.9 0.7 1.7 0.6 1.2 1.2 0.0 2.7 2.2 3.6 35.3 1.0 0.5 0.0 14.7 7.9 17.4 0.0 11.0 3.3 0.7 8.8 4.5 1.7 280.4 0.0 116.8 5.1 1.0 0.0 0.8 46.3 0.0 2.9 9.8 15.3 6.3 2.0 8.8 1.7 1.8 4.0 1.0 0.3 0.0 0.7 2.1 0.5 0.0 1.4 104.2 29.6 16.3 18.4 7.0 5.6 6.0 CDK10 PISSLRE ENSG00000185324 "Cyclin dependent kinase 10" Q15131 16 89680737-89696364 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007451, HPA059634, HPA067060" Uncertain Supported "Nucleoplasm,Midbody,Midbody ring" Yes Yes Nucleoplasm "Midbody, Midbody ring" "HPA007451: AB_2732400, HPA059634: AB_2684090, HPA067060: AB_2685772" "unprognostic (7.89e-2)" "unprognostic (8.08e-2)" "unprognostic (3.74e-3)" "unprognostic (9.87e-2)" "unprognostic (1.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.53e-1)" "unprognostic (9.06e-2)" "unprognostic (2.99e-1)" "unprognostic (2.13e-1)" "prognostic favorable (2.69e-4)" "unprognostic (2.58e-2)" "unprognostic (2.93e-1)" "unprognostic (3.32e-2)" "unprognostic (1.79e-1)" "unprognostic (6.88e-2)" "prognostic favorable (3.63e-4)" 12.3 19.9 16.8 16.4 23.8 17.3 10.1 14.8 21.9 11.1 18.3 8.1 16.4 23.4 12.1 21.7 14.4 14.4 19.4 8.7 15.3 12.6 22.2 33.9 11.8 14.0 13.3 19.4 11.3 22.2 21.6 27.7 13.6 15.8 13.6 12.6 8.1 17.2 8.9 17.5 14.1 20.7 9.0 10.7 15.9 19.0 8.7 13.6 8.0 27.1 10.1 12.1 10.8 14.5 7.8 14.5 3.4 15.3 15.2 13.3 8.8 14.7 9.6 7.7 3.1 3.2 6.1 8.1 12.2 6.9 8.7 2.9 7.4 11.2 13.1 6.2 10.5 5.4 10.3 3.3 17.0 5.5 2.9 8.1 5.1 10.8 0.8 13.4 8.3 9.4 7.5 5.7 5.5 8.3 5.8 15.1 8.7 13.4 1.8 9.9 19.2 10.0 23.8 15.8 16.0 7.3 14.6 10.5 18.4 15.6 11.7 7.6 16.5 15.3 7.1 3.6 9.1 16.7 13.2 13.4 5.9 15.3 6.1 8.3 6.6 3.6 4.0 9.0 14.3 8.4 3.2 11.7 3.4 12.9 15.3 10.9 6.8 11.4 8.9 14.5 7.8 13.3 10.9 1.5 15.2 11.2 10.0 8.8 8.8 16.8 23.8 14.8 21.9 15.3 12.6 13.3 19.4 15.8 13.6 11.9 28.2 16.7 22.2 13.7 17.3 4.8 45.9 18.7 9.1 26.2 23.6 25.3 36.5 23.6 5.0 17.5 42.9 0.0 11.0 16.4 18.6 26.1 9.2 37.6 16.3 17.5 65.1 19.6 16.7 5.4 22.2 13.0 18.6 14.4 38.5 10.3 14.2 35.1 11.7 45.1 33.8 6.5 11.3 23.1 29.8 13.6 23.3 17.5 50.1 18.6 CDK11A "CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, p58GTA, PITSLRE" ENSG00000008128 "Cyclin dependent kinase 11A" Q9UQ88 1 1702730-1724324 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Spermatocytes: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 33.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB010467, HPA025061, HPA073626" Supported Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "CAB010467: AB_631212, HPA025061: AB_1846407, HPA073626: AB_2686619" "unprognostic (6.25e-2)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (2.74e-1)" "unprognostic (9.32e-3)" "unprognostic (3.54e-2)" "unprognostic (2.25e-3)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.28e-1)" "unprognostic (5.58e-3)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.15e-6)" "unprognostic (1.97e-1)" "unprognostic (5.98e-2)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" 14.3 14.9 17.2 23.7 26.9 39.7 13.0 35.2 32.7 12.5 16.4 14.3 6.1 29.2 16.5 8.5 12.1 12.6 10.2 10.2 19.4 8.4 11.7 12.5 19.0 20.3 22.6 9.0 16.2 12.9 12.2 27.5 12.9 17.1 14.4 14.6 11.6 12.7 10.3 21.5 15.1 34.9 13.1 26.0 24.2 15.7 16.4 25.1 14.9 14.6 7.6 22.4 13.5 15.2 7.4 11.8 33.5 6.3 4.4 5.5 1.4 16.3 9.9 7.1 6.5 9.4 7.5 7.0 16.1 7.2 8.0 9.4 12.3 15.0 17.4 9.9 4.7 10.4 12.2 6.5 8.4 6.4 13.3 10.6 15.5 18.5 11.0 6.2 17.3 22.4 8.7 5.7 7.0 4.6 9.7 13.8 9.4 18.1 14.6 6.7 9.2 8.0 13.6 9.9 10.0 8.4 14.7 10.8 8.4 6.5 7.4 7.9 11.4 14.1 16.6 19.3 3.6 11.1 7.2 14.0 12.6 12.3 5.6 8.9 20.4 14.8 21.9 4.3 14.0 4.0 16.7 6.3 7.7 5.5 3.4 4.2 6.2 4.7 4.2 2.0 7.4 4.7 4.0 33.5 4.4 3.7 11.8 4.5 1.4 17.2 26.9 35.2 32.7 19.4 8.4 22.6 9.0 17.1 25.1 47.6 54.9 22.4 11.6 12.5 31.1 1.2 12.7 53.5 58.0 14.0 25.5 13.8 8.3 17.1 29.6 20.3 32.5 23.3 13.2 19.0 13.9 10.7 79.0 12.3 10.9 38.1 8.7 11.6 8.2 11.1 32.8 22.6 10.1 23.4 23.2 20.4 21.0 46.0 20.1 9.6 39.2 12.9 9.1 104.7 84.3 12.8 25.5 25.5 18.6 12.9 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461511-39564907 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 87.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 16.0 13.1 12.4 17.4 9.2 32.4 14.0 23.4 17.8 18.2 17.6 9.6 15.7 11.1 15.7 12.0 16.9 12.2 12.5 11.0 10.1 6.7 10.2 18.5 13.5 15.2 10.9 14.3 17.4 11.3 19.0 12.2 18.4 9.5 12.7 11.7 10.4 15.6 11.1 11.1 17.0 16.5 11.0 10.6 16.3 11.8 18.9 8.3 29.0 15.0 5.4 17.3 16.3 20.5 5.1 4.0 10.4 2.9 6.6 4.0 0.9 8.9 11.1 6.7 6.2 4.9 5.5 6.2 8.1 6.9 11.1 8.3 13.6 5.5 12.7 7.1 8.5 11.3 14.6 13.3 10.2 10.8 8.3 11.4 13.7 7.5 10.5 4.8 18.7 9.6 5.9 7.1 13.5 10.7 4.6 6.7 7.7 23.2 8.4 6.3 4.2 15.3 4.8 7.0 4.4 5.0 10.1 14.4 7.2 4.2 10.7 7.2 4.6 10.3 87.5 7.0 10.1 11.2 8.1 7.2 10.1 8.1 7.0 10.4 6.9 4.9 17.9 7.2 7.9 6.6 10.4 2.9 4.1 4.0 2.2 3.0 2.9 2.5 2.7 1.8 5.1 2.9 2.7 9.7 6.6 1.8 4.0 2.0 0.9 12.4 9.2 23.4 17.8 10.1 6.7 10.9 14.3 9.5 8.3 23.8 26.1 37.7 45.0 57.5 45.4 12.1 35.7 29.4 40.9 36.6 60.9 27.7 11.6 24.4 15.9 29.6 32.0 23.3 23.8 24.7 35.7 62.9 27.8 38.9 23.9 33.4 29.9 27.6 37.0 14.0 34.5 34.5 25.3 27.9 26.9 31.5 36.1 31.6 31.8 12.9 67.7 32.3 33.0 113.1 90.5 60.3 48.7 42.9 28.8 77.9 CDK13 "CDC2L, CDC2L5, CHED, KIAA1791" ENSG00000065883 "Cyclin dependent kinase 13" Q14004 7 39949646-40099580 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059241 Uncertain Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Nuclear speckles" "Golgi apparatus, Cytosol" "HPA059241: AB_2683956" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (2.72e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-1)" "unprognostic (4.18e-3)" "unprognostic (3.42e-2)" "unprognostic (8.09e-2)" "unprognostic (1.13e-2)" "unprognostic (3.77e-2)" "unprognostic (8.13e-2)" "unprognostic (8.20e-2)" "unprognostic (1.21e-1)" "unprognostic (3.33e-2)" "unprognostic (3.53e-1)" "unprognostic (3.53e-2)" 16.9 15.3 16.0 29.0 14.5 26.7 20.4 23.3 18.2 16.6 18.3 16.4 14.2 11.3 20.3 17.7 20.9 18.1 20.2 13.6 14.3 11.3 14.7 17.5 19.6 21.9 16.5 15.1 24.2 15.3 26.3 15.3 14.8 12.0 15.5 15.5 14.9 17.6 14.5 19.4 16.7 16.3 16.4 11.5 17.4 14.5 20.2 15.7 31.2 23.1 14.6 21.5 18.5 23.6 14.0 3.9 7.9 3.4 5.0 5.0 1.4 15.7 9.4 16.4 15.6 14.8 14.5 11.3 12.6 13.7 11.6 14.6 9.8 10.9 28.6 7.4 13.2 20.4 19.2 13.4 11.1 17.1 14.0 9.9 12.7 11.5 8.8 14.2 19.3 13.9 8.5 14.9 13.2 17.7 13.3 13.6 13.3 21.4 19.8 12.0 8.1 15.3 13.7 23.7 11.1 11.0 17.0 10.9 11.5 10.9 16.0 11.7 17.0 16.0 34.7 11.4 22.2 14.2 24.1 16.1 16.0 15.3 10.3 17.1 16.4 13.8 23.6 11.7 17.5 20.4 7.9 2.7 4.4 5.0 2.2 3.4 7.6 4.8 3.7 1.5 14.0 4.9 4.9 7.6 5.0 3.4 3.9 4.3 1.4 16.0 14.5 23.3 18.2 14.3 11.3 16.5 15.1 12.0 15.7 41.7 63.7 28.9 17.1 19.1 42.3 25.6 30.6 34.8 47.8 29.6 66.8 11.5 6.6 19.1 10.7 22.5 15.9 0.0 13.4 7.5 19.4 16.3 16.2 20.7 11.6 35.0 18.0 20.3 23.2 7.0 24.2 18.3 13.5 15.4 17.7 26.6 24.2 10.5 16.6 11.1 68.4 6.5 15.6 31.4 31.5 22.8 10.2 22.5 18.8 21.7 CDK14 "PFTAIRE1, PFTK1" ENSG00000058091 "Cyclin dependent kinase 14" O94921 7 90466424-91210590 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 16 "Early spermatids: 44.0;Horizontal cells: 163.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 7.5;memory B-cell: 9.8;naive B-cell: 5.3;neutrophil: 5.6" "Group enriched" "Detected in many" 9 "B-cells: 9.8;granulocytes: 7.5" "Cell line enhanced" "Detected in many" "Karpas-707: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015267 Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA015267: AB_1855249" "prognostic favorable (5.86e-4)" "unprognostic (3.96e-1)" "unprognostic (1.91e-2)" "unprognostic (2.09e-3)" "unprognostic (1.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.72e-1)" "unprognostic (4.48e-2)" "unprognostic (3.60e-2)" "unprognostic (3.09e-2)" "unprognostic (2.77e-3)" "unprognostic (2.91e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (7.79e-4)" "unprognostic (2.46e-1)" "unprognostic (2.86e-1)" "unprognostic (4.39e-3)" 8.2 4.7 19.8 7.1 19.4 6.1 8.3 28.6 34.9 10.6 5.2 3.7 0.6 2.7 8.6 3.2 3.1 12.0 11.9 11.5 25.8 15.5 19.8 12.7 9.2 10.9 17.3 17.4 14.9 14.2 3.8 14.2 5.9 22.8 11.3 3.4 4.3 7.7 7.0 5.4 2.7 3.8 7.4 7.0 7.5 7.4 7.2 4.5 0.9 13.1 1.6 11.9 6.9 6.7 9.8 0.9 7.5 0.7 0.1 0.2 0.6 7.1 0.0 14.3 1.8 13.4 13.7 3.3 6.0 5.7 3.7 4.0 0.1 3.5 25.4 0.7 5.9 5.4 2.1 0.7 8.4 7.1 0.0 3.4 0.0 4.7 0.1 6.2 7.2 0.1 9.7 2.1 10.9 3.9 6.1 4.7 0.1 0.1 31.3 7.4 0.0 0.0 2.8 9.0 0.0 3.9 19.5 19.7 19.3 1.9 1.9 3.2 9.2 15.2 0.0 0.3 6.7 1.9 3.6 11.5 15.9 20.4 13.3 9.2 17.7 13.5 18.1 6.0 9.5 15.5 7.5 0.3 0.5 0.0 0.7 0.0 9.8 0.0 0.0 0.9 5.3 0.0 0.0 5.6 0.1 0.5 0.1 0.2 0.6 19.8 19.4 28.6 34.9 25.8 15.5 17.3 17.4 22.8 4.5 17.9 3.2 27.7 7.4 0.7 5.1 11.1 10.2 4.0 13.6 10.4 0.0 0.2 6.6 9.4 44.0 2.1 0.0 0.0 5.8 0.1 12.5 8.3 0.0 9.6 4.0 163.7 1.7 1.3 5.1 27.0 14.4 4.6 5.0 1.0 0.1 8.8 9.4 0.2 14.9 18.1 9.5 0.0 6.6 3.8 6.5 1.1 0.0 0.5 0.0 2.3 CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.2;ovary: 9.8" "Group enriched" "Detected in some" 13 "Early spermatids: 23.2;granulocytes: 76.3;Late spermatids: 28.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 52 "basophil: 3.5;eosinophil: 6.9" "Lineage enriched" "Detected in single" 69 "granulocytes: 6.9" "Cell line enhanced" "Detected in some" "BJ hTERT+: 14.9;BJ hTERT+ SV40 Large T+ RasG12V: 12.2;HBF TERT88: 18.6;HMC-1: 35.2;LHCN-M2: 10.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" 1.3 0.2 0.1 5.2 0.1 0.0 3.7 0.3 0.1 3.4 2.3 0.1 0.1 0.3 4.1 20.2 1.1 1.0 4.2 0.3 0.1 0.0 0.4 0.1 3.3 0.1 0.1 0.1 9.8 0.2 0.0 0.5 0.1 0.1 2.0 0.7 1.4 0.6 0.3 0.7 1.1 3.0 3.9 0.1 0.1 1.1 2.5 0.1 0.1 0.2 1.2 1.2 1.6 1.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.7 0.0 3.2 14.9 5.6 12.2 0.0 1.5 0.0 0.0 1.3 0.2 0.0 0.0 0.0 18.6 0.0 0.0 1.0 0.0 0.0 0.2 0.0 35.2 2.1 0.0 1.5 0.8 0.2 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 2.2 0.0 0.0 0.2 0.0 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 76.3 0.0 0.0 0.0 0.0 0.0 0.0 28.0 0.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.0 0.0 0.0 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Microtubules, Cytosol" "Plasma membrane" "CAB016535: AB_785112, HPA000974: AB_2666162, HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 22.0 20.1 32.3 13.9 25.0 26.6 17.6 51.5 49.0 17.2 19.3 15.5 17.0 16.4 14.8 12.8 23.8 18.8 14.1 47.3 29.2 18.0 19.9 12.7 14.0 10.8 22.0 21.1 16.7 18.6 22.8 14.9 18.6 28.5 12.7 14.7 13.7 20.1 16.1 91.2 17.0 15.3 18.2 14.8 12.0 14.7 28.7 12.1 10.4 20.9 36.3 12.6 12.9 12.1 8.5 13.5 8.5 10.7 6.3 7.7 5.7 40.6 31.2 30.0 44.3 22.0 18.9 30.0 19.4 23.9 29.5 22.0 35.1 19.8 9.8 12.4 34.7 54.7 23.1 31.9 41.3 19.9 11.7 50.6 10.6 43.9 27.3 28.6 11.1 24.9 23.6 26.4 41.8 50.5 24.7 26.4 10.3 15.7 16.7 25.8 35.4 9.7 25.6 23.5 15.4 33.8 10.3 23.7 17.1 22.2 32.3 25.4 19.2 52.6 40.7 20.0 36.5 36.3 13.7 26.5 19.8 32.4 30.1 23.1 13.2 12.8 9.5 17.4 52.0 22.1 3.1 8.8 8.5 4.8 10.7 6.2 3.8 6.2 7.7 11.6 8.5 5.6 5.8 4.2 6.3 9.6 13.5 6.0 5.7 32.3 25.0 51.5 49.0 29.2 18.0 22.0 21.1 28.5 12.1 0.0 6.7 15.3 27.9 28.8 24.3 37.2 15.3 4.0 4.5 29.6 3.9 23.1 46.4 30.2 25.1 15.7 50.5 0.0 32.2 31.3 23.1 37.6 5.7 14.8 21.7 28.6 26.9 20.3 19.6 46.6 15.8 10.3 32.1 12.6 30.7 16.0 41.5 33.6 12.4 28.2 12.9 0.0 19.8 18.1 16.8 30.4 21.7 10.2 41.6 53.3 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400560 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 44.5;TIME: 53.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 16.3 9.1 20.6 13.9 47.0 31.5 14.7 17.8 35.7 11.8 12.9 23.6 3.4 9.2 20.7 7.5 11.7 10.9 12.9 9.4 25.3 17.3 9.2 12.4 15.9 15.2 23.8 21.0 12.9 8.0 9.9 7.3 24.3 14.8 11.4 9.8 5.7 7.5 9.3 7.3 9.1 9.3 23.4 19.6 15.8 7.9 19.9 28.0 29.6 9.4 6.1 16.6 11.0 10.7 9.6 5.3 29.1 4.7 16.5 14.8 8.6 4.9 4.2 11.0 2.9 5.4 14.3 7.8 11.1 15.7 9.8 9.3 2.5 2.9 7.4 7.7 8.0 5.3 4.5 6.5 6.9 13.4 7.8 5.0 10.6 2.8 3.5 11.7 5.6 6.1 10.3 7.1 14.5 26.2 17.4 44.5 6.3 7.7 6.0 22.1 3.0 5.3 8.8 4.8 2.4 7.3 9.3 5.9 6.3 11.6 4.2 5.7 3.9 6.5 6.1 8.1 8.7 4.6 5.1 53.3 8.7 3.3 4.6 6.0 8.5 6.5 7.9 3.3 2.4 6.4 29.1 3.4 8.9 12.7 4.7 13.7 9.6 10.4 14.4 5.3 8.8 14.8 12.6 12.8 16.5 4.6 3.9 8.1 8.6 20.6 47.0 17.8 24.6 25.3 17.3 23.8 21.0 14.8 28.0 14.9 6.2 24.4 8.9 23.8 10.8 8.9 5.1 9.4 10.3 8.7 15.7 10.0 0.0 4.6 2.7 42.9 6.0 0.0 3.2 25.8 15.5 10.4 17.4 8.9 10.5 4.8 14.5 35.6 15.3 3.2 9.2 9.4 16.9 7.2 7.4 20.2 5.7 3.5 8.9 6.9 9.2 6.5 27.8 6.5 7.6 22.6 11.4 27.7 5.5 11.8 CDK18 "PCTAIRE3, PCTK3" ENSG00000117266 "Cyclin dependent kinase 18" Q07002 1 205504595-205532793 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.7;heart muscle: 58.9" "Cell type enhanced" "Detected in many" 12 "Collecting duct cells: 69.8;Paneth cells: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 20.1;HeLa: 17.7;hTERT-RPE1: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045429 Approved Approved "Actin filaments" No No "Actin filaments" "HPA045429: AB_10961257" "unprognostic (7.95e-2)" "unprognostic (3.42e-1)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (7.06e-3)" "unprognostic (2.93e-1)" "unprognostic (2.95e-1)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (5.07e-6)" "unprognostic (6.07e-2)" "unprognostic (1.45e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.81e-5)" 2.6 4.3 13.6 2.7 31.8 1.0 2.4 4.2 25.0 7.6 6.9 38.1 20.2 17.3 3.4 4.0 2.7 5.7 6.4 58.9 22.1 16.2 13.7 4.7 6.5 1.9 47.8 16.7 7.5 10.7 3.7 4.0 9.6 22.1 3.1 6.1 5.3 16.5 23.5 3.9 1.6 15.1 4.8 98.7 3.5 9.1 0.9 36.4 0.4 4.8 1.4 2.5 3.7 4.7 0.1 1.4 0.0 2.1 0.6 0.9 0.6 11.7 0.8 0.1 0.6 0.0 0.0 12.7 0.2 2.4 0.5 3.1 5.3 8.8 7.0 1.8 0.1 1.0 10.6 2.6 20.1 0.5 1.9 2.3 1.6 17.7 5.4 2.3 0.0 0.0 1.3 1.0 0.0 0.4 17.2 0.0 10.0 0.1 8.5 0.1 9.5 0.6 0.3 10.0 3.4 0.4 0.9 0.0 8.8 1.9 7.5 4.1 1.6 3.6 1.7 7.8 14.7 7.9 3.4 0.0 0.0 4.8 0.0 0.0 2.4 1.1 1.4 0.1 5.0 2.0 0.0 0.8 0.0 0.1 2.1 0.9 0.0 0.2 0.0 1.4 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.6 13.6 31.8 4.2 19.7 22.1 16.2 47.8 16.7 22.1 36.4 0.0 0.3 0.0 6.7 3.1 4.7 25.0 7.6 0.0 1.2 69.8 0.0 4.9 6.6 15.9 1.6 1.9 20.6 0.0 5.8 1.9 4.8 1.9 0.0 3.9 5.1 0.0 5.8 1.3 1.6 2.8 0.9 3.6 3.3 7.2 12.9 19.1 6.3 98.2 1.4 15.4 1.2 6.5 12.5 1.4 10.0 1.1 1.6 0.5 11.5 5.9 CDK19 "bA346C16.3, CDC2L6, CDK11, KIAA1028" ENSG00000155111 "Cyclin dependent kinase 19" Q9BWU1 6 110609978-110815958 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.1" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 84.5;Late spermatids: 95.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 8.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007053 Approved Approved Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA007053: AB_1233803" "unprognostic (1.66e-2)" "unprognostic (1.84e-1)" "unprognostic (3.63e-1)" "unprognostic (3.00e-3)" "unprognostic (1.62e-1)" "unprognostic (2.66e-3)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.47e-2)" "unprognostic (2.96e-2)" "unprognostic (2.00e-3)" "unprognostic (3.94e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (4.72e-5)" "unprognostic (1.75e-1)" "unprognostic (9.78e-2)" "unprognostic (6.51e-2)" "unprognostic (9.50e-3)" 5.3 3.3 18.1 6.1 29.4 9.7 6.0 13.8 21.3 6.6 6.3 31.1 2.4 4.8 9.6 3.7 7.8 5.3 7.8 4.1 20.8 10.1 6.3 4.6 6.2 8.0 22.1 12.9 9.7 3.1 8.0 4.1 10.5 14.4 25.8 6.1 3.4 4.5 5.9 3.2 7.9 5.9 7.1 20.8 7.0 6.5 16.4 26.3 6.1 5.8 1.3 8.4 5.9 6.4 1.3 1.8 8.5 2.2 1.3 0.8 0.6 3.6 3.9 13.7 16.5 7.4 10.7 7.1 11.9 12.7 4.5 5.9 4.9 4.1 9.3 4.3 8.3 9.0 2.1 5.2 2.5 10.3 11.5 3.0 15.8 5.8 5.7 4.5 6.4 11.9 7.3 5.6 6.1 9.5 11.3 4.4 7.9 4.8 13.0 9.6 5.9 8.6 9.6 1.3 5.2 2.7 9.2 7.0 3.5 5.2 6.7 7.0 13.0 9.0 7.4 10.6 4.8 2.5 23.6 4.9 9.4 5.0 18.9 7.2 1.4 1.9 8.0 9.9 8.7 9.7 3.3 2.2 1.5 0.8 1.2 0.8 1.1 0.7 0.7 1.8 1.3 0.5 0.7 8.5 1.3 0.7 0.9 0.8 0.6 18.1 29.4 13.8 21.3 20.8 10.1 22.1 12.9 14.4 26.3 3.0 16.2 8.1 13.2 8.8 17.3 6.2 12.7 4.0 7.9 15.7 15.7 5.4 1.7 7.5 84.5 11.7 13.8 0.0 4.1 17.1 10.8 49.2 6.9 10.5 14.4 22.3 12.1 14.7 33.3 95.4 10.0 18.4 25.3 3.6 14.2 34.3 6.0 17.5 15.2 5.6 14.1 6.5 8.5 38.1 14.1 14.2 6.6 12.8 12.9 7.4 CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966769-55972784 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Cytotrophoblasts: 78.7;Extravillous trophoblasts: 67.5;Melanocytes: 82.7;Syncytiotrophoblasts: 142.8" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 107.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol NA NA Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: AB_2685748" "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavorable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" 10.7 7.6 4.5 20.8 6.5 18.7 11.5 4.2 4.3 12.6 11.6 3.5 6.0 6.1 10.7 6.4 13.6 10.8 12.6 10.1 5.4 2.2 8.3 16.7 19.5 12.2 6.0 2.0 14.2 8.3 5.2 4.2 49.0 7.3 10.8 9.1 51.2 9.3 9.9 10.8 14.6 9.3 11.8 5.0 12.5 10.1 7.8 5.1 39.3 9.5 10.7 14.7 16.7 10.1 9.3 10.8 5.2 3.9 4.5 7.6 4.3 16.8 9.1 20.1 11.1 4.1 5.3 37.0 21.0 11.0 26.2 24.5 19.2 16.3 16.1 15.8 7.8 10.5 10.8 15.3 9.2 26.6 18.9 15.0 18.5 15.1 7.3 1.3 14.6 13.4 2.8 2.3 17.7 6.1 7.6 13.2 16.7 17.5 14.7 18.1 13.0 30.3 12.4 8.0 11.5 13.6 29.6 19.3 12.1 7.6 16.6 8.3 10.7 24.0 8.8 107.8 12.0 19.0 10.7 7.3 18.1 17.5 13.9 15.3 8.3 9.6 20.0 10.3 10.7 15.6 5.2 3.6 3.1 7.0 3.9 7.0 9.3 3.2 5.0 2.7 6.1 3.0 5.3 1.7 4.5 1.6 10.8 7.6 4.3 4.5 6.5 4.2 4.3 5.4 2.2 6.0 2.0 7.3 5.1 14.9 3.7 5.2 20.1 24.8 0.0 2.6 12.7 5.3 9.1 1.8 0.0 78.7 1.7 10.5 0.4 15.0 2.1 0.0 5.0 67.5 17.6 10.9 10.4 8.9 11.6 1.6 5.2 8.6 4.8 0.2 13.8 6.3 82.7 47.7 6.3 3.8 9.0 0.0 4.2 3.8 3.4 0.0 14.4 2.9 7.7 27.5 142.8 5.7 6.8 18.0 CDK20 "CCRK, p42" ENSG00000156345 "Cyclin dependent kinase 20" Q8IZL9 9 87966441-87974753 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Ciliated cells: 25.4;Spermatocytes: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 7.2" "Group enriched" "Detected in many" 7 "NK-cells: 7.2;T-cells: 5.0" "Cell line enhanced" "Detected in many" "SCLC-21H: 14.4;THP-1: 21.7" "Low region specificity" "Detected in all" "HPA007666, HPA027379, HPA027401" Enhanced Supported Nucleoplasm NA NA Nucleoplasm "HPA007666: AB_10600002, HPA027379: AB_10599939, HPA027401: AB_10601553" "unprognostic (4.60e-2)" "unprognostic (6.48e-2)" "unprognostic (1.69e-2)" "prognostic favorable (2.59e-4)" "unprognostic (2.32e-1)" "unprognostic (4.33e-3)" "unprognostic (2.81e-4)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-3)" "unprognostic (4.04e-2)" "prognostic favorable (2.12e-5)" "unprognostic (8.24e-3)" "unprognostic (5.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.42e-2)" 2.6 16.2 10.8 2.4 13.0 1.6 4.1 8.7 17.1 8.7 5.0 6.1 5.1 5.3 7.2 6.0 2.8 19.5 5.6 3.0 8.6 10.7 8.2 3.2 4.0 2.0 5.8 14.3 9.5 4.8 7.6 10.8 3.1 9.3 6.1 3.4 7.7 3.6 8.6 2.1 3.6 7.6 5.5 3.1 1.6 3.7 17.7 5.2 0.8 6.8 1.2 1.1 6.3 3.0 0.1 0.8 0.4 0.8 7.2 5.0 1.3 2.4 3.0 2.4 7.6 1.7 2.4 1.0 2.2 4.2 5.9 5.5 0.7 3.6 0.0 3.3 3.6 10.3 3.1 0.0 2.1 2.4 5.9 2.5 0.0 1.9 0.0 7.4 2.8 3.4 1.9 4.4 9.3 3.8 4.6 0.0 5.3 0.3 0.0 1.7 7.1 1.9 0.8 1.9 5.3 1.1 0.0 0.0 0.1 7.4 2.0 14.4 4.1 2.5 3.0 3.6 0.8 3.3 21.7 0.0 2.6 1.0 0.5 2.4 3.8 3.6 0.0 9.3 1.9 2.8 0.0 0.7 0.4 1.3 0.8 0.5 0.0 3.0 1.9 0.7 0.1 5.0 3.2 0.1 7.2 0.7 0.8 2.7 1.3 10.8 13.0 8.7 17.1 8.6 10.7 5.8 14.3 9.3 5.2 3.0 4.1 0.0 1.5 1.9 5.2 2.0 2.5 25.4 5.7 1.8 2.0 3.6 1.7 4.2 4.7 0.5 5.4 0.0 1.3 1.9 3.3 2.5 1.1 0.9 0.9 7.9 0.0 0.6 0.0 1.7 4.0 1.1 0.0 0.0 2.0 4.8 1.5 0.0 6.3 5.3 13.5 6.5 2.3 25.0 2.9 1.9 3.3 0.5 2.9 0.7 CDK3 ENSG00000250506 "Cyclin dependent kinase 3" Q00526 17 76000906-76005999 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" 10 "Basal keratinocytes: 2.4;Distal tubular cells: 1.7;Ductal cells: 1.4;Exocrine glandular cells: 2.0;Melanocytes: 3.3;Pancreatic endocrine cells: 2.0;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007420 Uncertain Approved Cytosol NA NA Cytosol "HPA007420: AB_1078490" "unprognostic (6.77e-2)" "unprognostic (1.26e-1)" "unprognostic (3.69e-2)" "unprognostic (1.87e-3)" "unprognostic (6.41e-2)" "unprognostic (1.10e-3)" "unprognostic (1.61e-2)" "unprognostic (1.56e-1)" "unprognostic (8.12e-3)" "unprognostic (1.34e-1)" "unprognostic (9.80e-5)" "unprognostic (1.19e-2)" "unprognostic (6.75e-7)" "unprognostic (4.25e-2)" "unprognostic (1.63e-2)" "unprognostic (4.68e-1)" "unprognostic (4.47e-4)" 4.1 3.7 2.7 4.7 2.4 5.5 4.7 4.2 2.4 4.9 4.8 6.5 5.6 5.7 4.0 5.0 4.8 2.6 2.8 3.0 5.9 13.0 5.3 5.5 3.0 6.7 5.9 4.2 8.3 5.0 10.3 5.3 5.2 4.5 0.9 14.7 9.1 4.1 3.9 8.8 5.2 5.6 8.2 5.4 3.8 5.1 1.2 1.8 1.5 1.5 1.7 2.7 1.6 4.2 7.8 11.6 6.1 6.8 8.1 24.2 5.3 3.4 5.9 5.5 6.1 8.9 6.4 4.7 4.6 4.8 9.9 9.3 3.9 3.9 3.3 14.9 13.3 15.5 6.0 5.7 4.6 13.6 7.3 8.6 5.2 4.3 10.6 6.5 4.0 5.9 4.6 3.8 10.9 5.4 20.7 5.8 3.7 8.5 10.0 5.1 5.9 5.5 14.1 8.4 22.6 3.5 11.4 2.6 12.2 15.7 9.5 5.5 16.1 9.5 6.8 5.6 9.6 7.2 6.0 4.9 4.7 3.9 0.0 1.5 0.0 2.1 1.0 0.2 1.2 1.6 1.2 1.8 0.3 2.7 0.5 1.5 1.7 0.6 1.6 2.7 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.0 0.0 2.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 0.0 CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 10 "HBEC3-KT: 128.1;LHCN-M2: 141.4;RH-30: 445.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" NA NA Cytosol "Nucleoplasm, Nuclear membrane, Nucleoli" "CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: AB_2667497" "unprognostic (8.88e-2)" "unprognostic (2.53e-1)" "unprognostic (5.27e-2)" "unprognostic (9.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.09e-7)" "unprognostic (7.39e-2)" "unprognostic (3.23e-3)" "unprognostic (2.93e-2)" "unprognostic (3.19e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (3.15e-5)" "unprognostic (3.32e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-2)" 32.2 43.1 13.8 22.2 15.7 24.0 45.0 13.1 17.9 36.3 28.2 20.1 22.8 15.2 51.4 28.1 29.9 31.0 32.3 27.4 14.5 12.1 24.0 36.9 26.8 26.4 18.3 13.7 61.4 54.4 18.9 34.2 25.0 16.0 37.2 26.9 26.2 29.3 24.1 27.8 25.6 20.7 34.1 13.5 27.2 23.9 24.6 17.5 29.2 54.3 32.1 27.5 33.6 30.9 29.6 25.5 2.6 19.9 15.8 32.1 22.2 9.5 11.1 14.6 13.0 13.4 11.8 9.8 5.5 18.0 24.4 20.2 15.8 9.1 13.9 10.0 8.6 14.4 7.4 20.2 128.1 18.5 6.8 9.3 13.0 7.5 11.1 15.7 14.7 9.0 11.6 9.4 14.9 17.2 16.6 15.6 13.3 13.8 12.0 141.4 13.9 14.1 12.0 17.2 10.0 11.2 12.6 445.0 12.9 7.6 15.1 13.3 12.4 9.8 7.4 14.7 10.5 9.8 17.9 7.1 11.4 10.8 12.9 11.1 6.0 9.7 21.4 10.5 13.7 13.7 1.7 14.3 2.6 26.2 19.9 27.0 29.6 23.1 23.7 21.0 28.1 32.1 28.5 1.2 15.8 12.0 25.5 16.6 22.2 13.8 15.7 13.1 17.9 14.5 12.1 18.3 13.7 16.0 17.5 20.8 25.0 32.0 62.9 79.7 15.3 0.5 48.4 4.0 23.9 45.4 9.8 64.6 59.7 71.7 10.1 44.2 11.3 23.3 53.6 108.9 77.4 41.8 68.1 32.1 111.7 17.5 43.8 34.4 23.2 6.8 59.2 34.0 50.6 54.1 33.5 51.3 55.4 7.0 59.4 66.3 15.3 32.3 54.2 25.9 40.3 75.3 39.1 34.1 78.3 32.5 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053812-151058530 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB008909: , HPA064535: AB_2685280" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 4.5 11.3 24.4 6.9 30.4 6.1 5.3 13.6 36.1 5.3 6.1 6.7 4.5 7.9 4.5 17.4 6.5 5.0 6.2 5.8 25.0 19.7 9.0 7.7 5.3 6.0 15.4 15.4 3.2 5.8 8.9 7.9 5.3 20.8 5.8 6.3 3.2 6.0 6.3 5.7 6.5 6.2 6.0 8.6 5.2 5.7 3.1 7.7 6.8 6.0 3.6 6.9 6.7 3.1 6.6 21.5 9.0 21.7 9.5 14.9 10.6 11.7 14.1 13.2 21.5 14.6 10.7 6.6 7.8 12.8 15.3 12.6 10.0 11.0 11.6 27.9 9.6 22.8 8.4 21.2 11.8 7.0 9.1 12.6 12.7 12.4 9.9 9.6 10.2 23.9 11.6 8.9 12.6 3.9 21.4 10.3 18.2 12.9 8.5 15.3 22.7 27.6 21.0 14.5 18.9 22.3 13.5 5.4 12.9 13.3 8.9 8.4 35.9 11.2 13.8 14.7 12.6 6.4 9.0 8.7 15.1 3.9 11.3 14.5 19.7 21.5 4.5 23.7 14.8 27.0 7.8 19.0 9.0 6.9 21.7 5.4 6.6 6.8 6.8 21.5 5.9 5.1 6.2 2.8 9.5 16.4 12.8 14.9 10.6 24.4 30.4 13.6 36.1 25.0 19.7 15.4 15.4 20.8 7.7 0.0 5.9 11.5 6.4 3.2 11.5 3.2 7.6 8.1 7.9 10.4 2.0 20.0 33.2 19.0 0.6 6.3 7.1 0.0 16.6 10.2 6.6 5.0 31.0 9.6 37.8 0.0 8.6 6.2 21.6 0.9 4.4 14.3 10.1 20.8 9.1 11.5 18.7 14.4 10.6 24.0 4.7 6.5 5.0 2.6 9.7 5.5 7.6 8.5 9.6 7.6 CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836594 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.6" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 219.8;Late spermatids: 186.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 93.5;REH: 45.7" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavorable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (2.33e-5)" 6.6 11.3 6.0 9.1 7.5 22.5 5.9 2.4 6.0 7.8 10.0 9.6 5.7 7.5 6.0 5.9 8.5 4.6 7.8 6.6 6.9 4.2 6.5 7.5 7.3 7.4 7.0 5.2 5.0 10.0 25.7 4.2 20.5 7.5 6.1 9.2 4.4 10.9 6.1 2.0 11.6 9.4 9.8 7.5 6.3 10.8 5.4 8.0 74.6 4.3 9.2 10.3 6.7 9.0 3.6 5.6 6.5 4.8 3.9 7.1 2.3 6.2 2.9 8.0 5.1 2.3 2.6 1.7 6.4 4.0 3.2 3.0 7.8 4.8 4.8 3.7 4.3 2.0 3.8 4.4 9.2 7.6 10.5 3.1 12.0 5.5 7.5 1.4 7.4 0.6 2.6 5.0 4.3 20.4 3.0 1.2 19.6 11.5 13.3 5.7 1.2 93.5 0.8 2.5 7.9 2.6 45.7 28.1 8.1 4.4 0.1 4.2 27.3 0.7 2.2 3.7 6.1 0.1 12.3 4.7 10.5 16.5 4.1 12.9 7.1 0.1 6.4 1.5 25.5 13.9 4.9 1.9 6.5 5.2 3.9 5.9 2.0 5.5 5.6 4.0 3.6 7.1 4.0 1.1 3.9 4.8 5.6 2.8 2.3 6.0 7.5 2.4 6.0 6.9 4.2 7.0 5.2 7.5 8.0 23.8 3.0 11.9 19.5 53.5 0.2 14.8 25.5 4.0 27.3 21.0 0.0 42.7 8.3 31.7 219.8 24.1 11.0 0.0 20.1 3.4 21.6 18.1 24.3 18.4 15.0 0.0 16.1 7.4 23.4 186.0 4.6 21.9 18.6 20.8 46.7 0.5 63.1 14.0 3.2 5.1 0.0 6.5 22.1 2.6 46.4 44.2 14.8 20.3 68.3 23.3 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 13 "Cytotrophoblasts: 97.9;Extravillous trophoblasts: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932, HPA008453" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA Nucleoplasm "Nucleoli fibrillar center, Plasma membrane, Cytosol" "CAB004364: AB_627243, HPA007932: AB_1078492, HPA008453: " "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavorable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 7.9 12.9 10.9 6.2 15.2 44.1 14.0 10.8 14.7 9.4 12.7 6.0 6.3 15.8 9.4 8.6 23.4 18.5 16.5 8.1 11.5 9.3 13.8 10.6 10.1 8.8 7.6 9.7 7.7 9.1 3.3 16.2 22.9 11.2 11.2 14.8 6.6 13.2 6.5 15.9 15.4 9.8 12.1 9.2 7.9 13.9 29.0 7.8 12.1 20.0 15.6 15.5 10.7 11.7 15.6 15.0 22.4 11.3 12.4 15.3 7.8 3.6 7.7 1.8 0.5 2.4 11.6 14.7 6.4 7.7 10.7 17.4 16.6 1.9 2.8 10.1 1.7 12.4 2.5 1.4 2.8 5.8 1.3 7.0 0.4 8.1 7.9 0.4 6.7 3.2 14.3 13.8 9.0 2.8 9.4 13.5 15.6 10.3 4.5 4.9 0.7 4.0 14.7 1.7 3.7 7.4 6.6 0.4 1.1 1.6 1.0 0.6 6.5 1.5 5.8 3.4 6.4 11.6 0.6 2.6 0.0 3.2 0.9 5.1 4.8 8.4 3.7 0.8 4.0 0.8 7.3 10.9 22.4 8.6 11.3 14.8 12.4 12.9 15.3 15.0 15.6 11.1 13.2 10.0 12.4 8.0 11.2 12.8 7.8 10.9 15.2 10.8 12.7 11.5 9.3 7.6 9.7 11.2 7.8 14.9 10.4 2.4 16.5 51.3 6.3 8.9 5.1 48.2 10.3 5.2 11.8 97.9 13.3 21.5 6.2 11.3 9.2 0.0 19.0 285.4 10.2 19.9 15.1 6.6 21.2 1.6 2.9 6.7 8.2 3.6 6.9 10.2 6.8 9.0 11.4 9.0 22.5 14.0 6.7 20.7 8.2 25.8 12.2 25.4 15.8 36.6 54.0 9.6 11.8 28.6 CDK8 K35 ENSG00000132964 "Cyclin dependent kinase 8" P49336 13 26254104-26405238 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 55.8;Late spermatids: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044721 Approved Nucleoplasm NA NA Nucleoplasm "HPA044721: AB_2679059" "unprognostic (3.28e-3)" "unprognostic (2.25e-3)" "unprognostic (2.08e-1)" "unprognostic (3.88e-3)" "unprognostic (2.30e-2)" "unprognostic (1.05e-2)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (5.00e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-3)" "unprognostic (2.12e-1)" "prognostic favorable (9.23e-4)" "unprognostic (1.43e-2)" "unprognostic (1.88e-1)" "unprognostic (6.37e-2)" 7.6 8.8 10.1 10.4 8.5 5.2 5.6 26.9 11.3 5.9 24.0 6.0 13.8 13.8 11.2 6.5 10.0 7.0 11.2 7.6 8.3 7.3 9.4 10.4 6.7 5.2 7.8 7.9 6.1 12.7 8.4 10.2 10.6 8.2 7.8 11.2 4.6 9.0 19.2 9.7 6.1 15.0 12.7 6.0 6.4 11.7 16.3 9.9 12.8 6.4 6.9 7.2 15.5 11.0 1.9 1.7 3.4 1.6 1.0 2.1 1.3 6.9 5.7 11.6 11.8 6.2 7.6 7.2 13.4 9.2 10.0 7.2 16.6 9.7 7.4 5.9 6.9 8.0 8.6 13.3 9.0 12.6 17.1 7.4 14.1 4.6 5.7 4.3 22.0 8.1 5.5 8.7 7.5 12.7 5.5 7.3 12.1 21.8 0.0 9.0 7.4 16.8 10.3 9.2 10.5 7.1 10.6 11.5 5.1 5.8 6.5 9.9 5.8 5.7 10.9 9.8 9.6 3.9 10.1 7.4 6.4 8.2 11.7 7.3 5.7 10.1 13.6 4.0 9.3 7.6 0.4 0.9 3.4 1.1 1.6 1.9 1.0 1.5 2.1 1.7 1.9 2.1 1.7 0.0 1.0 1.2 1.0 0.6 1.3 10.1 8.5 26.9 11.3 8.3 7.3 7.8 7.9 8.2 9.9 8.9 4.1 4.5 6.7 17.5 19.1 5.0 7.6 0.0 5.7 1.8 23.6 7.2 8.3 8.5 55.8 6.8 9.7 0.0 7.2 8.3 9.3 11.0 0.0 5.4 7.1 17.5 8.1 6.2 7.5 83.1 7.2 6.6 8.5 8.2 7.8 7.1 10.6 11.5 7.8 11.5 16.6 6.5 11.3 27.8 17.5 20.8 8.1 6.9 10.5 9.1 CDK9 "C-2k, CDC2L4, PITALRE, TAK" ENSG00000136807 "Cyclin dependent kinase 9" P50750 9 127785679-127790787 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004216, HPA006738" Supported Approved "Nucleoplasm,Cytoplasmic bodies" NA NA Nucleoplasm "Cytoplasmic bodies" "CAB004216: AB_627245, HPA006738: AB_1078493" "unprognostic (3.60e-1)" "unprognostic (1.71e-1)" "unprognostic (5.44e-3)" "unprognostic (1.04e-3)" "unprognostic (1.93e-1)" "unprognostic (3.97e-2)" "unprognostic (2.07e-1)" "unprognostic (5.84e-2)" "unprognostic (2.66e-1)" "unprognostic (8.36e-2)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (1.37e-1)" "unprognostic (1.00e-1)" "unprognostic (3.52e-2)" "unprognostic (8.78e-3)" 26.2 27.0 22.8 18.9 22.4 33.9 17.4 31.0 26.8 23.1 21.9 22.9 24.7 16.6 22.5 20.1 22.7 29.1 21.5 22.9 26.3 23.4 18.5 48.7 23.3 26.6 23.4 18.8 43.7 29.1 15.5 28.4 19.8 20.6 20.7 10.8 18.7 20.6 21.6 14.6 26.6 21.4 21.0 17.9 29.0 17.7 22.3 16.1 29.3 25.8 18.3 24.2 17.0 17.6 6.0 8.9 5.1 6.4 18.6 9.9 2.9 9.0 16.4 10.3 11.3 11.7 9.2 13.5 9.3 13.7 9.7 8.8 12.2 10.2 15.9 10.9 10.5 13.4 18.3 6.8 15.2 3.7 14.2 8.1 14.8 17.8 10.0 17.1 14.3 23.8 16.1 18.6 10.3 11.6 12.6 20.0 14.2 12.8 21.3 8.7 23.8 15.6 21.6 22.8 13.7 17.6 45.2 8.8 22.7 14.1 10.1 10.2 12.2 14.0 14.8 8.3 8.4 18.6 13.6 22.9 11.7 13.2 10.0 9.0 38.9 29.9 14.2 10.9 9.8 10.6 3.7 3.4 4.9 9.9 4.5 9.9 3.5 5.6 7.9 4.4 6.0 6.3 7.7 5.1 18.6 6.4 8.9 3.8 2.9 22.8 22.4 31.0 26.8 26.3 23.4 23.4 18.8 20.6 16.1 11.9 14.3 20.4 20.9 21.4 13.1 12.9 15.3 18.7 7.9 10.4 2.0 18.7 13.3 26.6 3.2 26.7 12.9 0.0 32.7 18.8 16.4 18.5 24.3 23.6 20.6 23.8 18.5 31.9 17.0 4.3 18.1 18.9 15.1 64.9 11.8 16.2 30.5 11.8 29.4 12.7 7.5 0.0 22.7 7.5 24.0 19.3 42.9 23.5 13.1 23.1 CDKL1 KKIALRE ENSG00000100490 "Cyclin dependent kinase like 1" Q00532 14 50329404-50416461 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 11 "Alveolar cells type 1: 17.9;Ciliated cells: 34.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059605, HPA065919" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA059605: AB_2684080, HPA065919: AB_2685578" "unprognostic (4.12e-3)" "unprognostic (3.22e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.02e-1)" "unprognostic (3.23e-3)" "unprognostic (9.36e-3)" "unprognostic (2.63e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (5.53e-8)" "unprognostic (1.21e-1)" "unprognostic (7.96e-2)" "unprognostic (9.39e-3)" "unprognostic (3.31e-3)" 7.1 2.1 7.5 1.8 5.1 0.9 3.0 2.7 20.2 14.1 5.9 1.6 2.5 8.4 12.1 2.3 2.6 16.4 2.6 2.9 7.1 2.4 18.8 1.1 4.3 3.0 2.0 12.3 10.5 2.0 1.4 1.4 4.9 2.9 4.0 5.7 1.6 2.5 8.4 1.7 3.0 3.0 7.7 3.1 3.7 2.0 1.9 1.4 1.3 5.0 6.1 2.1 7.0 5.6 5.7 1.3 6.0 2.5 3.8 6.7 2.6 6.1 4.9 0.6 2.4 6.5 7.9 0.3 2.1 3.9 2.2 2.6 2.0 5.8 0.4 2.6 4.6 2.2 4.2 0.9 0.6 2.5 6.7 2.4 6.5 2.1 1.7 7.4 5.9 3.5 1.7 3.6 4.6 10.1 1.8 8.5 6.2 2.7 2.6 1.0 0.3 1.9 3.1 0.7 1.6 2.3 0.7 2.8 1.9 6.9 2.3 1.1 1.3 2.5 16.7 0.6 0.1 0.2 5.0 2.7 5.7 2.9 5.7 4.7 0.9 0.4 0.4 1.0 6.2 7.0 6.0 2.5 4.4 6.3 2.3 6.2 4.6 4.4 6.7 1.3 5.7 3.4 3.7 1.4 3.8 0.3 1.2 4.1 2.6 7.5 5.1 2.7 20.2 7.1 2.4 2.0 12.3 2.9 1.4 17.9 6.9 1.3 3.2 2.7 0.4 0.4 0.0 34.8 4.5 10.4 0.0 0.1 5.0 0.9 0.3 2.1 4.7 0.0 1.6 0.1 4.7 1.2 1.1 0.2 0.3 0.0 1.7 6.7 1.9 0.9 8.3 1.1 0.0 0.0 2.3 0.8 1.2 3.7 3.2 5.5 0.7 0.0 1.3 0.0 0.2 2.4 0.2 2.5 3.4 1.4 CDKL2 "KKIAMRE, P56" ENSG00000138769 "Cyclin dependent kinase like 2" Q92772 4 75578005-75630716 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.7" "Cell type enhanced" "Detected in many" 9 "Alveolar cells type 2: 55.4;Ciliated cells: 28.1;Spermatocytes: 46.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Cell line enhanced" "Detected in some" "A-431: 5.7;HEK 293: 3.8;HHSteC: 4.4;RPTEC TERT1: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040672 Approved Nucleoplasm,Centrosome NA NA "Nucleoplasm, Centrosome" "HPA040672: AB_10794744" "unprognostic (2.07e-1)" "unprognostic (9.96e-2)" "unprognostic (6.91e-2)" "unprognostic (3.80e-5)" "unprognostic (3.43e-2)" "unprognostic (2.71e-2)" "unprognostic (1.59e-1)" "unprognostic (8.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.88e-15)" "unprognostic (5.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-1)" "unprognostic (7.52e-2)" 0.7 2.4 7.1 1.2 11.1 0.7 1.2 7.7 13.2 1.7 2.0 6.2 0.0 1.0 1.7 2.3 2.3 4.1 1.4 1.3 5.1 6.7 11.8 0.7 9.2 1.3 7.1 7.0 3.8 1.6 5.7 8.9 0.7 12.5 2.0 2.4 3.4 1.2 2.0 0.7 0.9 0.9 1.5 7.4 0.9 1.5 27.7 6.1 0.0 6.9 0.0 2.0 1.1 0.9 0.4 0.0 0.2 0.0 0.0 1.6 0.1 5.7 0.7 0.3 0.0 0.3 0.3 0.0 0.3 1.8 2.4 2.0 0.5 1.2 0.1 0.9 0.1 2.3 0.8 0.0 0.5 2.3 0.2 3.8 0.0 0.2 0.0 4.4 0.0 0.1 1.5 2.1 0.4 0.8 1.9 0.1 0.0 0.0 0.4 0.9 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 8.2 0.3 3.1 2.5 0.0 0.0 1.2 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 2.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.4 1.6 0.0 0.0 0.6 0.5 0.2 0.0 0.0 0.0 1.2 0.1 7.1 11.1 7.7 13.2 5.1 6.7 7.1 7.0 12.5 6.1 23.8 55.4 0.0 0.4 0.1 16.6 0.8 0.0 28.1 7.9 8.7 3.9 0.0 6.6 2.0 24.5 0.0 0.0 0.0 0.2 0.5 0.2 0.3 1.1 0.0 0.1 9.5 1.7 0.6 0.0 16.4 1.7 0.5 1.7 0.0 0.2 10.4 0.1 0.0 1.1 20.7 19.5 0.0 0.0 46.8 1.7 0.3 0.2 1.0 2.6 0.1 CDKL3 NKIAMRE ENSG00000006837 "Cyclin dependent kinase like 3" Q8IVW4 5 134286350-134371047 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.4" "Group enriched" "Detected in many" 8 "Early spermatids: 261.7;Late spermatids: 219.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA027751 Uncertain Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA027751: AB_10601256" "unprognostic (4.70e-2)" "unprognostic (2.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.43e-1)" "unprognostic (3.98e-2)" "unprognostic (3.43e-3)" "unprognostic (5.93e-2)" "unprognostic (2.12e-3)" "unprognostic (1.49e-1)" "unprognostic (8.47e-4)" "unprognostic (2.82e-1)" "unprognostic (9.85e-4)" "unprognostic (8.33e-2)" "unprognostic (4.88e-2)" "unprognostic (7.10e-3)" "unprognostic (3.43e-3)" 2.5 2.7 7.0 2.2 7.1 1.6 2.5 7.0 8.5 2.6 2.4 5.9 5.5 2.3 3.9 5.3 2.6 3.7 2.6 6.6 6.1 6.5 4.5 2.8 2.2 2.5 8.0 4.3 3.0 2.4 3.2 6.5 2.2 8.6 2.8 2.6 3.9 2.0 3.2 7.5 2.7 2.5 4.6 8.4 2.7 2.2 33.4 9.3 1.3 3.9 2.1 3.0 2.8 2.2 1.5 2.7 1.0 1.1 1.4 4.0 1.3 1.0 2.1 3.1 2.2 5.4 4.6 1.3 2.9 2.6 1.3 3.2 1.9 1.5 2.7 1.8 1.8 6.0 0.9 2.6 1.8 2.6 2.9 2.0 1.4 2.3 3.3 3.3 0.6 0.9 2.2 4.7 3.9 1.2 2.2 1.3 6.5 1.5 1.2 3.5 1.1 2.1 8.0 2.1 0.6 1.0 3.4 1.3 0.8 1.7 0.9 4.8 1.4 2.1 0.5 3.5 3.7 1.8 1.6 0.9 2.6 0.6 3.5 1.0 3.3 4.4 5.2 4.0 2.1 2.0 0.0 0.9 1.0 0.9 1.1 4.0 1.5 1.4 2.5 2.7 1.0 3.8 3.8 0.2 1.4 0.4 1.6 2.3 1.3 7.0 7.1 7.0 8.5 6.1 6.5 8.0 4.3 8.6 9.3 0.0 3.0 0.0 5.7 9.6 12.7 1.6 0.0 5.3 3.4 5.2 3.9 2.4 8.3 2.6 261.7 3.6 0.5 0.0 4.4 1.6 6.9 4.0 3.5 1.8 3.1 6.4 2.9 3.1 0.6 219.5 4.6 4.0 10.1 2.8 0.7 10.0 1.5 0.9 8.5 6.1 9.6 0.0 5.6 30.5 13.2 9.7 3.8 3.2 1.1 3.3 CDKL4 ENSG00000205111 "Cyclin dependent kinase like 4" Q5MAI5 2 39175646-39229588 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "blood: 3.2;testis: 7.9" "Group enriched" "Detected in some" 14 "Alveolar cells type 1: 3.0;Ciliated cells: 8.1;Club cells: 3.4;Early spermatids: 8.3;Late spermatids: 4.5;Spermatocytes: 6.5;Spermatogonia: 3.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.6;T-reg: 3.2" "Group enriched" "Detected in many" 25 "B-cells: 1.6;T-cells: 3.2" "Cell line enhanced" "Detected in some" "HAP1: 1.9;HL-60: 5.0;RT4: 3.4;SH-SY5Y: 6.8" "Low region specificity" "Detected in many" HPA067895 Uncertain NA NA "HPA067895: AB_2685920" "unprognostic (3.57e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "unprognostic (7.46e-3)" "unprognostic (3.26e-2)" "unprognostic (4.26e-1)" "unprognostic (3.82e-2)" "unprognostic (6.13e-3)" "unprognostic (1.77e-2)" "unprognostic (8.43e-2)" "unprognostic (8.45e-4)" "unprognostic (8.59e-2)" "unprognostic (4.95e-1)" "unprognostic (3.08e-1)" "unprognostic (3.26e-2)" 0.3 1.1 0.3 0.0 0.6 0.0 0.3 0.1 0.7 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.5 0.9 0.2 0.0 0.4 0.1 0.2 0.3 0.3 0.0 1.6 1.2 0.4 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.3 7.9 0.3 0.1 0.1 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.5 0.4 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.3 0.7 0.3 5.0 1.1 0.3 0.0 0.1 0.0 0.2 0.1 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.7 0.1 0.0 0.0 0.0 0.2 3.4 0.6 6.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 3.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 8.1 3.4 0.0 0.0 0.2 0.0 0.2 8.3 0.0 0.0 0.0 0.2 0.4 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.5 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.0 0.3 0.0 0.0 6.5 3.8 0.0 0.0 0.0 0.0 0.0 CDKL5 "CFAP247, EIEE2, STK9" ENSG00000008086 "Cyclin dependent kinase like 5" O76039 X 18425583-18653629 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Cell type enhanced" "Detected in many" 7 "Horizontal cells: 76.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 7.7;eosinophil: 2.1;neutrophil: 4.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 7.7" "Cell line enhanced" "Detected in many" "A549: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002847, CAB011577" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB011577: AB_727019, HPA002847: AB_1080107" "unprognostic (7.01e-2)" "unprognostic (4.86e-2)" "unprognostic (1.41e-1)" "unprognostic (1.25e-4)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" "unprognostic (9.63e-3)" "unprognostic (2.05e-3)" "unprognostic (1.66e-1)" "prognostic favorable (5.54e-4)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "unprognostic (2.67e-3)" "unprognostic (1.99e-1)" 3.3 3.2 8.0 1.8 24.7 3.2 4.3 3.9 28.0 5.4 2.7 7.7 1.8 1.5 4.5 2.8 5.2 2.8 3.1 5.0 8.0 3.7 6.3 2.2 6.9 1.4 3.5 13.2 6.7 4.5 6.2 5.0 5.4 5.9 6.7 2.2 2.0 3.9 4.4 3.0 3.5 1.9 4.0 5.7 2.3 4.9 14.0 5.7 1.6 5.1 0.8 2.1 5.6 4.6 0.7 1.0 7.7 1.0 0.5 0.6 0.2 1.7 12.3 3.5 3.1 3.3 4.5 2.5 2.0 3.8 2.8 3.2 4.0 2.3 1.9 0.4 1.3 5.5 0.5 4.0 3.0 5.9 0.5 2.6 0.0 7.1 3.2 1.6 0.1 0.8 2.6 3.1 6.8 7.1 1.7 1.3 2.2 0.1 2.0 4.2 1.7 0.8 0.8 7.2 1.6 3.0 0.7 3.8 0.1 2.5 9.0 0.7 4.5 4.5 1.1 2.2 7.4 1.7 0.7 7.3 4.3 1.9 7.9 1.5 0.3 0.1 0.3 2.4 0.5 4.2 7.7 1.0 2.1 0.6 0.6 0.3 0.2 0.4 0.3 0.3 0.7 0.6 0.6 4.7 0.5 0.6 1.0 0.2 0.2 8.0 24.7 3.9 28.0 8.0 3.7 3.5 13.2 5.9 5.7 23.8 19.0 0.0 8.3 0.8 16.1 12.0 5.1 6.7 9.1 7.0 31.4 20.0 6.6 5.7 27.2 4.5 0.0 0.0 8.1 2.5 3.1 18.1 1.1 3.0 3.7 76.3 2.4 4.9 5.3 41.5 5.5 1.8 0.0 2.8 1.9 27.7 6.6 0.0 4.9 7.5 19.5 32.3 4.2 2.3 9.8 1.1 39.6 0.8 1.5 24.3 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625136-125676255 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ductus deferens: 80.0;seminal vesicle: 66.8" "Cell type enhanced" "Detected in many" 9 "Cholangiocytes: 33.1;Extravillous trophoblasts: 31.3;Spermatogonia: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 11.7" "Lineage enriched" "Detected in many" 6 "T-cells: 11.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" HPA044364 Supported Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 3.0 2.5 2.5 9.0 2.8 14.9 2.1 1.1 2.2 2.5 5.2 1.3 80.0 5.0 1.9 10.2 6.5 1.7 3.6 1.5 2.4 2.4 3.7 2.0 1.8 9.6 3.0 1.2 3.8 4.0 25.5 3.5 3.8 1.5 2.9 6.3 1.6 2.6 66.8 1.2 2.9 5.2 2.3 3.0 3.6 2.8 7.2 1.5 22.4 1.8 4.5 8.8 3.8 3.3 1.9 1.8 1.9 0.7 1.2 11.7 1.0 13.0 10.6 23.9 14.5 4.9 10.5 10.4 18.3 8.8 11.7 12.6 25.9 28.8 34.0 18.8 7.2 15.6 15.7 14.6 9.6 14.5 21.3 6.7 63.1 8.9 13.2 1.5 32.2 12.0 5.4 2.0 14.8 10.5 7.0 13.9 23.2 32.0 30.0 15.4 6.7 47.8 15.8 24.2 21.3 9.6 29.1 22.3 17.9 10.8 17.4 15.1 16.0 15.0 10.4 4.4 16.9 28.0 10.5 9.3 16.9 14.4 8.1 16.8 6.7 12.0 48.5 6.2 24.3 19.8 1.9 0.5 0.3 1.3 0.7 1.2 1.9 3.5 1.6 1.1 1.5 3.3 2.0 0.4 1.2 0.4 1.8 11.7 1.0 2.5 2.8 1.1 2.2 2.4 2.4 3.0 1.2 1.5 1.5 3.0 0.3 6.0 4.4 5.6 1.4 3.7 33.1 2.7 5.7 7.0 0.0 9.6 3.3 3.7 3.3 1.9 3.3 23.3 1.0 31.3 5.6 2.0 0.0 0.8 9.4 0.0 1.7 4.9 0.0 2.2 1.4 2.4 0.0 4.6 5.6 2.7 2.4 3.7 1.1 6.8 1.5 0.0 4.1 23.3 60.3 4.3 6.5 4.4 12.0 1.4 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Erythroid cells: 23.3;Spermatogonia: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 5.6 8.3 2.5 13.0 7.0 13.7 5.6 0.7 5.6 6.6 9.8 2.5 4.8 6.8 4.8 10.9 10.0 4.3 6.0 6.0 4.1 2.3 5.3 6.5 7.9 10.1 6.7 1.6 12.9 6.7 1.2 4.2 10.1 5.1 8.3 10.6 8.7 7.0 5.8 2.2 6.3 8.5 5.4 5.0 9.8 5.8 9.7 3.6 13.1 7.5 4.8 13.7 6.2 6.7 11.8 8.7 6.5 8.4 2.9 4.4 3.7 14.9 4.8 13.7 17.0 3.9 19.5 8.8 7.4 8.7 9.8 14.4 12.1 10.2 17.7 6.3 5.2 10.6 14.4 20.8 13.6 11.5 12.6 16.0 23.3 9.2 20.2 3.8 14.7 17.1 8.2 6.3 12.6 11.2 6.0 10.8 14.2 14.0 15.5 9.2 21.0 11.8 23.7 19.3 18.5 12.2 25.6 9.4 20.6 6.1 6.2 8.1 4.6 8.3 14.7 8.2 10.6 10.1 13.6 3.7 7.9 9.5 6.9 3.9 9.4 16.5 34.6 7.5 15.5 10.0 6.5 3.7 1.2 1.1 8.4 2.3 11.8 2.2 2.1 8.7 8.4 4.4 2.8 0.3 2.9 4.1 7.0 2.8 3.7 2.5 7.0 0.7 5.6 4.1 2.3 6.7 1.6 5.1 3.6 8.9 4.5 7.5 4.5 5.7 1.0 1.0 0.0 2.7 4.5 1.8 0.0 10.5 0.0 1.7 4.7 2.2 2.0 23.3 1.2 11.7 8.9 2.3 3.5 0.9 8.4 0.0 1.2 3.1 2.1 0.5 5.8 6.6 1.7 2.8 4.7 0.6 1.3 3.5 4.2 3.2 1.2 0.0 2.8 2.5 20.2 1.9 2.9 4.3 7.9 3.4 CHUK "IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16" ENSG00000213341 "Conserved helix-loop-helix ubiquitous kinase" O15111 10 100188298-100229619 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001402, CAB004240, CAB018564" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB004240: AB_627784, CAB018564: AB_649197, HPA001402: AB_1079125" "unprognostic (8.61e-3)" "unprognostic (1.70e-1)" "unprognostic (3.74e-2)" "unprognostic (3.01e-1)" "unprognostic (3.02e-2)" "unprognostic (5.93e-2)" "unprognostic (4.02e-2)" "unprognostic (2.09e-1)" "unprognostic (8.58e-2)" "unprognostic (8.39e-2)" "unprognostic (6.73e-2)" "unprognostic (1.49e-1)" "prognostic favorable (1.27e-4)" "unprognostic (2.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-3)" "unprognostic (2.22e-1)" 16.6 16.6 14.0 14.3 18.9 21.3 14.2 16.0 15.8 11.8 15.0 13.0 13.9 16.1 14.7 12.4 13.5 12.0 11.7 14.5 13.3 17.6 27.2 35.8 14.0 20.8 17.9 6.9 11.4 14.5 19.6 18.2 14.2 16.4 12.9 17.6 9.5 13.9 12.5 23.6 11.0 20.6 16.1 18.6 18.7 15.1 12.5 15.6 22.5 14.5 11.7 15.5 13.8 13.6 3.7 3.4 7.2 4.8 4.0 4.3 1.4 15.8 13.5 13.8 20.6 13.3 12.0 10.6 20.3 20.0 19.0 23.2 15.1 9.4 21.6 12.0 13.8 13.2 15.8 23.0 10.7 21.3 22.9 19.9 14.3 10.7 16.6 11.4 26.4 21.1 9.6 11.5 21.8 21.4 13.2 13.5 17.9 16.2 17.9 20.6 9.6 20.9 16.3 9.0 12.7 9.9 13.7 15.4 9.8 12.0 10.3 8.3 12.3 11.0 8.5 17.6 11.4 17.0 16.2 14.1 11.9 13.4 12.9 23.0 21.1 19.0 21.0 13.0 21.5 9.4 2.6 3.0 5.1 2.4 4.8 4.0 3.7 3.0 4.3 3.4 2.1 3.3 4.2 7.2 4.0 3.2 2.1 2.8 1.4 14.0 18.9 16.0 15.8 13.3 17.6 17.9 6.9 16.4 15.6 11.9 7.8 9.0 4.9 17.5 5.0 6.9 5.1 4.0 4.5 5.2 2.0 5.5 10.0 6.6 6.7 8.3 8.3 0.0 10.3 6.5 5.6 8.2 8.1 13.0 9.4 12.7 5.8 6.2 17.2 6.1 5.8 10.7 6.8 11.8 6.3 4.8 7.9 6.6 5.6 15.3 4.8 19.4 8.1 8.0 13.6 16.7 11.6 7.5 6.0 10.9 CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685790-119877291 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;brain: 35.0" "Cell type enhanced" "Detected in many" 14 "Cone photoreceptor cells: 82.5;Early spermatids: 63.4;Late spermatids: 28.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol NA NA Cytosol "HPA019082: AB_1846803, HPA048812: AB_2680528, HPA075506: AB_2686752" "unprognostic (5.64e-2)" "unprognostic (5.00e-2)" "unprognostic (8.16e-2)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.61e-6)" "unprognostic (6.02e-2)" "unprognostic (7.78e-2)" "unprognostic (4.42e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-2)" "unprognostic (2.55e-3)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.30e-1)" 1.4 4.4 14.7 3.3 14.0 15.3 1.6 12.7 35.0 1.6 4.6 2.9 0.0 4.0 1.3 1.5 3.2 0.9 1.6 1.0 9.8 5.7 5.7 1.4 3.0 3.4 3.2 21.9 0.7 0.7 1.2 2.9 2.6 7.4 1.0 5.3 0.6 1.3 1.0 1.3 5.1 3.5 2.6 5.0 5.6 3.5 8.3 9.5 5.9 1.5 0.1 4.9 1.7 1.7 0.4 0.0 0.0 0.1 0.0 1.2 0.8 15.1 13.7 12.0 11.3 1.1 3.3 7.1 11.7 9.7 12.2 9.2 8.7 6.3 11.0 6.3 9.0 6.0 9.5 8.2 6.8 16.9 7.8 6.0 13.9 8.8 5.4 0.1 7.3 12.8 0.7 0.8 14.6 9.0 4.4 9.3 12.2 8.8 9.3 11.5 7.6 13.2 11.1 6.5 5.7 9.3 12.1 21.9 3.6 2.4 6.7 8.6 4.7 19.4 3.8 9.2 6.3 13.7 5.3 7.1 15.3 14.1 10.4 12.7 6.3 7.1 7.5 10.1 8.1 23.6 0.0 0.0 0.0 0.4 0.1 0.0 0.4 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 14.7 14.0 12.7 35.0 9.8 5.7 3.2 21.9 7.4 9.5 6.0 8.8 0.8 0.6 3.0 7.4 1.6 0.0 1.4 9.1 8.7 82.5 0.9 0.0 0.2 63.4 1.1 0.4 0.0 0.7 4.0 1.1 0.3 1.1 0.8 2.9 0.0 1.7 1.3 1.9 28.5 1.1 1.0 3.3 0.0 1.1 15.4 0.1 0.0 1.1 5.7 15.0 0.0 0.4 11.5 3.5 1.1 0.8 2.5 1.6 1.0 CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864744 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Nucleoplasm, Nuclear membrane" "CAB033141: AB_1121713, HPA062405: AB_2684753" "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.19e-2)" "unprognostic (4.50e-3)" "unprognostic (1.52e-1)" "unprognostic (2.77e-3)" "unprognostic (1.78e-2)" "unprognostic (2.09e-2)" "unprognostic (1.09e-2)" "unprognostic (5.63e-3)" "unprognostic (2.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.28e-4)" 26.3 55.1 27.8 30.5 43.4 97.6 40.2 40.1 40.7 42.2 23.0 19.9 39.1 12.9 29.1 34.5 26.3 19.1 35.8 26.7 31.0 21.9 21.8 35.3 28.2 30.1 56.0 23.1 48.1 20.9 36.6 41.5 40.0 34.4 34.3 16.5 13.7 25.6 37.1 27.3 32.1 14.9 36.8 55.2 32.4 15.1 12.4 52.6 25.0 30.4 20.2 25.6 51.2 71.8 13.2 9.8 26.2 6.2 6.5 14.4 7.4 8.2 6.2 10.4 3.2 11.9 13.1 8.2 9.0 12.8 9.1 12.2 11.6 5.4 2.8 6.1 5.6 5.3 8.9 13.1 4.1 18.7 12.5 11.6 8.5 15.7 14.3 7.1 8.8 14.4 6.0 18.9 11.4 20.2 10.9 5.3 4.5 10.2 37.3 12.9 5.6 10.4 26.8 6.6 5.2 14.2 10.6 12.4 14.8 6.3 5.4 10.5 8.3 7.8 2.9 13.0 6.5 2.4 6.1 8.1 10.2 7.0 9.8 9.8 22.0 9.1 6.5 6.5 7.2 6.9 26.2 6.2 13.3 13.6 4.4 13.1 13.2 12.8 12.1 4.1 10.1 14.4 11.4 12.7 6.5 4.2 9.8 13.0 7.4 27.8 43.4 40.1 40.7 31.0 21.9 56.0 23.1 34.4 52.6 41.7 97.6 120.6 205.3 149.9 55.8 85.6 28.1 76.3 79.6 26.2 94.2 37.9 16.6 25.9 1.9 110.1 100.8 23.3 23.3 39.1 151.1 171.5 133.9 37.6 51.4 49.3 128.8 78.0 91.9 5.1 86.0 167.5 146.8 47.7 56.3 46.1 27.4 66.6 71.1 11.1 91.9 109.9 142.2 31.2 22.0 132.6 75.5 146.6 44.8 153.2 CLK2 clk2 ENSG00000176444 "CDC like kinase 2" P49760 1 155262868-155278491 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055366, HPA059507" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA Nucleoplasm "Nuclear bodies" "HPA055366: AB_2682795, HPA059507: AB_2684044" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (2.84e-2)" "unprognostic (3.16e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.38e-1)" "unprognostic (2.36e-1)" "unprognostic (1.36e-2)" "unprognostic (7.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (2.95e-9)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "prognostic favorable (5.43e-4)" 15.3 16.6 14.6 15.0 19.0 12.9 17.1 33.1 20.2 22.3 18.0 18.7 18.1 14.5 22.6 19.9 15.5 18.2 13.9 11.8 17.1 7.3 17.3 18.2 14.7 22.2 16.9 16.9 24.7 15.9 29.2 21.6 19.2 13.5 22.1 13.5 16.1 16.4 18.2 10.4 21.4 15.6 17.0 13.5 27.0 13.7 13.7 20.3 18.1 22.9 8.0 22.2 16.7 20.1 2.8 1.9 4.8 1.7 0.7 4.1 1.1 5.9 5.1 18.7 5.7 9.4 5.1 16.0 5.3 6.5 4.1 4.2 5.4 4.3 13.0 7.4 3.6 2.2 8.6 9.3 6.9 3.9 9.4 7.3 10.3 5.4 6.9 8.1 12.8 10.4 4.1 6.4 6.0 12.2 11.9 7.2 11.1 14.5 9.0 6.2 10.3 8.7 7.6 12.2 15.0 7.3 9.7 11.3 13.9 10.5 13.4 8.9 12.7 2.0 6.4 4.9 14.7 9.8 15.7 4.7 2.5 6.8 4.6 4.4 17.2 14.7 11.8 5.1 9.2 2.9 4.8 1.7 3.4 2.0 0.8 2.9 2.8 3.4 1.8 1.8 2.4 3.4 4.1 2.1 0.7 0.8 1.9 1.7 1.1 14.6 19.0 33.1 20.2 17.1 7.3 16.9 16.9 13.5 20.3 14.9 22.4 4.8 4.8 4.0 5.8 13.3 12.7 4.0 18.2 7.0 3.9 6.8 0.0 5.2 6.3 8.3 4.3 0.0 3.8 7.3 7.2 3.9 9.3 5.8 6.0 4.8 6.4 8.0 10.5 5.4 7.2 5.8 3.3 7.2 7.9 5.4 4.4 3.5 2.8 2.8 5.7 6.5 3.3 8.3 3.8 4.0 10.4 4.4 6.3 4.3 CLK3 clk3 ENSG00000179335 "CDC like kinase 3" P49761 15 74598500-74645414 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046817 Approved Supported "Nucleoplasm,Intermediate filaments" NA NA Nucleoplasm "Intermediate filaments" "HPA046817: AB_10964124" "unprognostic (4.10e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (2.05e-6)" "unprognostic (1.91e-3)" "unprognostic (7.91e-2)" "unprognostic (5.76e-2)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (8.14e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "unprognostic (9.73e-2)" "unprognostic (2.48e-1)" "unprognostic (2.25e-2)" 20.9 17.2 15.7 24.7 22.5 62.7 31.1 23.4 18.8 24.9 24.6 23.1 16.4 18.6 24.1 17.7 25.3 17.3 21.2 16.4 17.8 13.5 17.2 16.0 19.6 21.9 29.3 14.5 23.7 21.8 19.0 19.9 27.9 16.7 20.6 14.4 19.9 24.8 20.9 28.4 24.1 20.7 19.8 19.2 23.8 19.6 31.5 23.3 28.8 21.0 12.0 23.7 23.2 19.8 38.9 36.0 60.7 46.0 43.6 43.4 39.7 22.3 14.2 18.8 10.5 24.2 18.6 14.9 15.3 24.2 21.9 26.9 19.3 14.8 20.4 11.4 13.6 30.6 15.8 35.0 14.7 14.3 29.0 19.2 25.0 21.1 13.3 38.5 6.7 19.4 23.2 29.4 28.8 24.0 26.8 24.0 20.8 12.2 14.9 12.7 15.8 19.9 22.7 12.0 22.2 10.1 16.1 9.0 13.4 17.1 16.3 10.6 12.5 12.2 13.6 13.5 15.1 12.9 13.5 11.0 13.0 10.0 8.1 20.0 24.5 19.6 16.8 11.4 33.1 16.4 32.9 34.4 45.0 38.5 37.4 37.4 37.7 41.1 39.7 31.9 38.9 42.1 40.1 60.7 43.6 46.0 36.0 43.4 39.7 15.7 22.5 23.4 18.8 17.8 13.5 29.3 14.5 16.7 23.3 6.0 35.5 20.9 38.8 40.0 34.9 14.9 20.4 17.4 18.2 12.2 53.0 22.9 26.6 29.6 59.6 28.3 37.1 23.3 21.0 31.4 22.7 32.5 20.8 10.9 24.3 27.0 28.2 17.2 24.0 14.8 25.6 28.5 27.0 32.5 24.6 17.7 28.8 28.1 19.1 14.2 42.2 12.9 24.4 37.1 17.5 36.6 49.0 39.2 22.6 53.1 CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 288.4;Late spermatids: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043746 Approved Approved "Actin filaments" No No "Actin filaments" "HPA043746: AB_2678650" "unprognostic (9.46e-2)" "unprognostic (2.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.44e-2)" "unprognostic (1.59e-1)" "unprognostic (7.16e-3)" "unprognostic (2.67e-1)" "unprognostic (2.04e-2)" "unprognostic (4.37e-2)" "unprognostic (5.92e-2)" "unprognostic (2.90e-3)" "unprognostic (9.62e-3)" "unprognostic (1.13e-2)" "unprognostic (1.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (1.14e-3)" 12.2 16.4 17.0 17.4 18.4 11.4 17.3 53.8 24.1 17.9 12.2 11.9 18.3 12.4 17.0 16.4 10.5 11.0 13.1 11.4 15.9 9.5 11.8 16.0 10.9 20.3 21.2 12.7 17.4 16.2 15.4 20.2 13.9 16.3 16.7 8.9 10.8 14.4 17.0 20.6 19.5 11.3 11.3 25.8 17.0 11.0 15.7 22.0 15.0 15.8 9.7 12.7 11.4 18.0 13.2 7.8 16.1 6.1 7.7 13.8 5.2 6.7 6.3 5.8 8.4 17.5 14.7 9.7 6.7 7.5 4.0 7.4 6.7 5.5 3.9 5.4 2.8 4.5 9.0 7.5 5.4 6.6 14.1 5.9 1.5 11.8 8.1 6.5 3.1 4.9 6.7 7.8 6.4 8.6 13.2 2.7 2.7 3.5 11.6 5.1 2.8 4.0 11.4 3.0 4.6 3.9 4.0 5.2 5.7 3.9 2.1 6.5 4.4 7.5 4.0 6.9 3.4 4.3 6.6 5.6 8.2 2.9 4.2 7.1 7.6 2.8 3.0 5.9 7.6 4.1 6.5 6.1 12.0 10.0 4.1 13.2 13.2 10.3 8.9 5.9 10.4 13.8 10.6 16.1 7.7 4.4 7.8 9.5 5.2 17.0 18.4 53.8 24.1 15.9 9.5 21.2 12.7 16.3 22.0 14.9 26.7 50.0 37.2 28.3 66.4 19.3 7.6 32.1 23.9 14.0 37.3 16.5 5.0 7.3 288.4 24.8 13.5 23.3 4.1 13.0 20.8 26.1 27.6 11.9 8.8 27.0 5.8 17.2 13.1 350.8 28.4 23.8 15.1 12.6 10.7 34.6 6.5 11.8 27.6 7.7 76.4 19.4 36.0 23.2 17.7 21.5 13.3 34.8 9.1 22.2 COQ8A "ADCK3, CABC1, COQ8, SCAR9" ENSG00000163050 "Coenzyme Q8A" Q8NI60 1 226897536-226987545 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Kinase, Transferase" "Disease mutation, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 216.5" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 2: 18.7;Collecting duct cells: 31.4;Exocrine glandular cells: 28.2;monocytes: 19.8;Proximal tubular cells: 20.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 32.8;RPMI-8226: 29.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061662 Supported Mitochondria NA NA Mitochondria "HPA061662: AB_2684578" "unprognostic (6.37e-3)" "unprognostic (2.09e-2)" "unprognostic (2.29e-1)" "unprognostic (9.06e-2)" "unprognostic (8.94e-2)" "unprognostic (2.49e-1)" "unprognostic (4.42e-2)" "unprognostic (3.50e-3)" "unprognostic (1.81e-1)" "unprognostic (4.02e-1)" "unprognostic (4.15e-3)" "unprognostic (8.67e-2)" "unprognostic (2.40e-2)" "unprognostic (9.24e-2)" "unprognostic (2.82e-1)" "unprognostic (8.88e-2)" "unprognostic (2.62e-1)" 13.3 25.4 2.8 2.7 4.5 5.3 8.5 14.5 3.9 3.2 7.3 4.1 4.2 6.9 3.6 5.5 7.3 5.0 6.1 41.0 2.7 1.8 3.8 17.7 2.7 4.1 5.0 2.4 7.2 20.3 1.6 1.6 2.0 3.8 6.5 2.0 1.9 7.2 5.0 216.5 4.4 4.4 7.8 2.9 3.5 8.8 3.0 4.7 2.7 4.6 50.2 5.8 10.2 3.5 15.2 9.3 32.3 11.5 9.9 11.8 11.6 3.1 5.8 1.5 4.4 4.7 3.0 23.4 1.5 1.3 2.1 2.8 9.1 5.1 9.4 7.2 1.0 1.2 3.7 2.9 3.3 0.5 9.9 32.8 6.6 4.8 15.0 1.0 9.9 4.0 5.9 5.0 1.7 2.3 2.1 1.0 9.7 11.3 7.8 0.3 4.3 5.7 14.6 6.4 24.3 11.9 5.7 7.0 29.9 0.7 2.4 24.1 9.9 2.9 11.7 8.5 1.7 6.2 13.5 1.2 2.5 2.3 3.4 5.4 17.5 15.3 4.9 2.3 11.3 2.4 19.7 11.5 32.3 8.7 8.6 8.3 12.1 8.5 7.7 9.3 15.2 11.8 9.0 21.9 9.9 6.5 4.1 10.6 11.6 2.8 4.5 14.5 3.9 2.7 1.8 5.0 2.4 3.8 4.7 3.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 4.0 7.9 31.4 0.0 10.4 13.3 14.2 0.0 0.0 0.0 0.0 28.2 7.8 0.0 0.0 12.8 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 19.8 0.0 0.0 14.5 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 COQ8B "ADCK4, COQ8, FLJ12229" ENSG00000123815 "Coenzyme Q8B" Q96D53 19 40691529-40718207 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Alveolar cells type 1: 11.9;Ciliated cells: 16.0;Collecting duct cells: 12.2;Ductal cells: 12.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027229, HPA027277, HPA027279, HPA028303" Supported Enhanced Mitochondria NA NA Mitochondria "HPA027229: AB_10600100, HPA027277: AB_10599857, HPA027279: AB_10601219, HPA028303: AB_2672551" "unprognostic (7.57e-2)" "unprognostic (9.48e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-2)" "unprognostic (2.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.85e-1)" "unprognostic (2.27e-1)" "unprognostic (2.82e-2)" "unprognostic (1.48e-1)" "unprognostic (2.93e-2)" "unprognostic (6.18e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (2.65e-2)" 13.6 17.8 21.1 13.1 16.4 11.5 10.0 24.1 19.2 13.6 13.6 18.6 14.8 17.9 15.0 13.2 16.6 26.5 16.7 14.7 15.7 10.7 11.8 15.6 12.1 12.2 15.5 12.1 16.3 19.4 12.6 32.7 7.9 13.2 15.1 5.7 12.3 16.8 17.6 10.3 12.9 18.6 16.2 15.6 12.1 17.5 12.5 16.7 16.8 15.5 6.9 13.2 14.8 11.8 12.9 15.0 17.7 15.6 9.7 13.1 10.5 8.3 34.3 7.0 13.5 6.3 6.1 6.5 7.8 8.5 5.9 6.3 10.7 15.2 11.2 15.1 4.5 7.0 7.3 4.9 8.7 2.1 13.4 10.2 10.7 20.9 5.9 10.8 3.7 16.8 8.0 9.3 4.3 5.2 6.7 6.6 13.9 5.7 6.2 4.1 5.1 4.8 4.5 5.4 9.2 3.6 8.0 9.9 8.5 10.2 14.2 12.6 10.3 10.5 16.1 16.9 4.5 14.4 14.0 6.2 5.1 17.3 3.6 4.6 6.8 5.5 5.7 19.3 4.2 7.0 15.8 15.6 14.6 11.6 15.4 13.1 12.9 9.0 12.4 15.0 11.7 8.9 9.1 17.7 9.7 13.7 8.7 8.8 10.5 21.1 16.4 24.1 19.2 15.7 10.7 15.5 12.1 13.2 16.7 11.9 4.6 0.0 0.0 0.0 0.0 0.0 0.0 16.0 4.5 12.2 0.0 9.4 10.0 12.4 0.0 0.0 0.0 0.0 9.5 7.9 0.0 0.0 1.1 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 10.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 82.5;lymphoid tissue: 82.6" "Group enriched" "Detected in many" 8 "Extravillous trophoblasts: 97.9;Hofbauer cells: 277.3;Kupffer cells: 200.7;Macrophages: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 60.7;non-classical monocyte: 82.5" "Lineage enriched" "Detected in many" 4 "monocytes: 82.5" "Group enriched" "Detected in some" 5 "BEWO: 51.8;SK-BR-3: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1500000000 "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 20.9 12.4 18.2 28.1 18.9 1.8 7.7 2.8 13.5 9.3 8.3 25.4 1.1 9.2 5.9 13.1 8.4 7.9 16.1 8.7 16.4 13.7 7.8 15.1 13.7 25.4 21.3 6.0 5.3 5.2 5.9 6.4 52.1 17.1 8.5 8.4 16.8 8.0 8.7 3.0 5.8 14.5 16.2 25.8 82.6 9.0 4.9 23.0 3.1 4.2 2.9 8.2 16.4 4.7 0.0 19.1 2.9 82.5 0.0 0.1 13.9 1.7 0.0 0.0 0.0 0.8 0.2 51.8 0.1 0.0 0.0 0.0 1.5 0.0 2.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.1 0.0 19.8 0.0 0.8 0.0 7.4 0.0 0.3 0.0 0.0 1.3 0.0 0.1 0.0 2.6 0.9 0.0 0.4 18.1 0.5 0.1 60.7 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 2.9 0.0 82.5 1.4 0.0 13.9 18.2 18.9 2.8 13.4 16.4 13.7 21.3 6.0 17.1 23.0 0.0 6.7 0.5 0.0 2.5 0.0 2.8 5.1 1.4 0.0 0.0 0.0 2.9 0.0 0.0 3.7 2.2 0.0 0.0 0.0 97.9 3.3 0.0 2.3 0.8 277.3 0.0 0.0 4.9 200.7 3.5 1.7 125.7 3.3 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.4 12.9 1.3 0.5 0.2 1.1 22.1 2.2 0.0 0.0 CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782057-74803198 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 67.2" "Cell type enhanced" "Detected in many" 6 "B-cells: 91.8;Kupffer cells: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Enhanced Vesicles,Cytosol No No 1500000 "Vesicles, Cytosol" "CAB011203: AB_259070, HPA026488: AB_1847273, HPA028425: AB_10600899" "unprognostic (1.05e-1)" "prognostic favorable (5.14e-5)" "unprognostic (2.59e-3)" "prognostic favorable (8.22e-4)" "unprognostic (4.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "unprognostic (4.12e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.74e-4)" "prognostic favorable (1.07e-4)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" 9.3 8.0 9.5 39.3 11.0 19.9 12.6 18.7 13.4 12.1 13.5 11.8 7.3 16.1 13.9 6.4 33.3 10.6 11.2 14.0 9.8 8.5 8.0 20.9 15.6 67.2 11.1 7.4 10.5 6.7 6.6 10.4 8.8 12.2 9.8 8.9 9.8 13.2 7.0 8.7 14.9 26.2 8.5 10.9 62.7 13.1 8.1 10.6 62.7 8.1 9.5 47.4 17.4 13.2 35.6 22.8 49.6 46.8 16.3 30.7 19.9 12.9 18.3 9.0 14.7 8.6 6.6 7.7 8.7 8.4 16.6 11.8 16.7 12.0 58.0 11.5 7.8 15.4 13.5 18.8 17.5 4.7 28.1 23.2 49.1 6.7 16.7 11.9 25.6 62.6 9.3 8.7 11.8 10.6 8.3 12.5 27.4 14.1 20.2 9.8 21.9 18.4 15.1 11.1 11.7 13.1 20.5 7.7 42.3 7.6 28.8 14.9 10.3 11.3 23.7 15.1 6.0 16.3 37.8 10.8 20.1 10.6 15.7 15.0 10.8 21.8 59.2 10.4 49.0 13.6 20.7 19.7 49.6 23.4 42.4 20.0 29.4 20.3 23.1 22.8 35.6 15.7 18.4 39.1 16.3 46.8 13.2 30.7 19.9 9.5 11.0 18.7 13.4 9.8 8.5 11.1 7.4 12.2 10.6 3.0 11.6 91.8 7.2 8.2 16.5 8.1 12.7 5.3 6.8 8.7 5.9 6.3 1.7 8.5 10.0 11.5 27.7 0.0 12.0 11.0 7.6 9.3 25.5 25.0 46.4 27.0 9.1 12.3 77.9 2.1 8.3 44.5 8.5 36.9 25.3 6.5 15.2 17.3 7.8 6.8 4.1 6.5 8.5 3.8 11.3 8.0 4.7 60.9 22.8 10.5 CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492197-149551552 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Suprabasal keratinocytes: 741.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016680, HPA051334" Uncertain Approved Cytosol NA NA Cytosol "CAB016680: AB_1614518, HPA051334: AB_2681446" "unprognostic (4.27e-3)" "unprognostic (5.85e-3)" "prognostic favorable (1.15e-4)" "unprognostic (7.39e-2)" "unprognostic (2.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.27e-2)" "unprognostic (5.56e-2)" "unprognostic (4.38e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (5.47e-2)" "unprognostic (1.56e-1)" "unprognostic (7.92e-2)" "unprognostic (4.41e-2)" "unprognostic (6.28e-3)" "unprognostic (6.92e-2)" 33.5 35.8 26.0 26.9 35.2 71.0 40.2 32.0 39.3 33.8 38.2 28.2 40.5 23.2 41.0 29.4 66.1 31.8 36.0 45.7 24.4 26.1 24.0 30.1 37.5 27.3 28.0 29.8 31.7 23.9 46.9 30.9 28.7 38.0 38.1 31.4 25.5 38.5 39.3 51.4 48.4 31.8 45.8 33.9 23.6 34.2 28.6 24.1 38.6 32.0 53.1 41.1 45.0 40.0 28.6 40.6 47.4 39.6 34.2 41.9 40.8 36.9 24.7 41.6 39.4 43.0 52.7 44.5 52.8 50.2 41.2 43.4 48.1 50.1 19.7 58.5 56.1 44.2 37.8 29.3 71.1 63.0 28.5 17.7 26.7 28.6 22.1 38.7 41.8 43.0 43.1 73.8 46.2 74.5 45.6 47.4 35.6 22.5 29.7 46.4 23.2 38.3 16.9 21.8 40.9 60.2 28.7 33.0 22.4 28.7 64.4 32.1 28.9 39.2 52.6 64.3 38.5 49.3 36.4 47.0 48.5 25.5 32.1 50.3 27.6 35.4 30.4 45.3 30.4 58.6 47.4 36.6 35.4 29.0 38.7 33.1 28.6 36.7 32.9 40.6 23.4 39.9 34.0 31.1 34.2 39.6 24.2 41.9 40.8 26.0 35.2 32.0 39.3 24.4 26.1 28.0 29.8 38.0 24.1 137.0 158.5 75.9 513.8 608.0 132.0 46.4 73.9 278.4 290.0 109.9 60.9 146.8 77.9 135.8 55.7 139.6 98.3 23.3 160.7 185.9 198.0 381.5 112.3 94.7 120.9 143.0 124.9 225.9 143.6 66.9 96.4 139.7 145.1 118.2 136.8 145.0 155.3 98.2 105.0 78.9 100.0 155.2 201.9 125.6 93.5 741.0 293.5 102.2 111.1 404.2 CSNK1A1L MGC33182 ENSG00000180138 "Casein kinase 1 alpha 1 like" Q8N752 13 37103259-37105664 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "blood: 10.5;testis: 9.0" "Group enriched" "Detected in some" 8 "Early spermatids: 23.1;Late spermatids: 19.5;Spermatocytes: 11.4" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 40 "neutrophil: 10.5" "Lineage enriched" "Detected in single" 42 "granulocytes: 10.5" "Not detected" "Not detected" HPA051334 Uncertain Cytosol NA NA Cytosol "HPA051334: AB_2681446" "unprognostic (1.23e-2)" "unprognostic (1.59e-1)" "unprognostic (3.19e-2)" "unprognostic (3.54e-2)" "unprognostic (2.40e-2)" "unprognostic (5.40e-2)" "unprognostic (8.90e-2)" "unprognostic (3.47e-1)" "unprognostic (1.47e-3)" "unprognostic (4.50e-1)" "unprognostic (2.02e-1)" "unprognostic (2.28e-3)" "unprognostic (3.45e-1)" "unprognostic (2.38e-1)" 0.0 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.0 0.0 0.0 0.0 0.0 0.1 0.2 10.5 0.2 0.1 0.2 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 10.5 0.1 0.2 0.1 0.2 0.2 0.0 0.0 0.0 1.5 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.1 0.5 0.0 0.0 0.0 0.1 0.4 0.9 0.0 0.0 0.1 0.0 0.0 1.8 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.4 1.1 2.4 0.2 0.0 0.0 1.0 CSNK1D "CKID, CKIdelta, HCKID" ENSG00000141551 "Casein kinase 1 delta" P48730 17 82239023-82273731 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 287.2;Late spermatids: 600.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015410 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" Nucleoplasm "CAB015410: AB_831049" "unprognostic (1.07e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.38e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.38e-6)" "unprognostic (8.05e-2)" "unprognostic (1.09e-1)" "unprognostic (5.00e-2)" "prognostic favorable (9.62e-5)" "unprognostic (2.23e-3)" "prognostic unfavorable (8.34e-4)" "unprognostic (3.54e-1)" "unprognostic (2.52e-1)" "unprognostic (5.52e-3)" "unprognostic (4.74e-2)" 30.1 36.3 30.8 25.9 30.8 21.0 26.3 36.3 42.8 30.9 33.0 27.7 32.9 32.6 37.9 29.8 31.3 38.0 34.9 28.5 26.2 26.9 32.0 33.5 30.1 25.8 27.2 27.8 31.4 42.8 34.2 35.9 32.8 30.3 35.3 19.3 28.4 38.0 37.7 52.3 26.7 42.3 34.1 21.4 36.4 32.5 48.3 24.6 29.2 33.0 31.8 33.7 31.4 26.1 6.4 11.4 29.6 12.1 8.7 7.6 7.1 21.6 25.8 14.7 20.3 19.4 20.8 29.6 31.9 20.1 22.9 21.5 21.2 18.7 19.8 25.3 22.7 24.3 21.0 13.8 32.3 18.5 16.8 33.4 24.6 20.5 22.6 56.4 20.2 18.9 31.4 23.0 15.5 23.2 28.6 33.3 14.7 27.7 10.5 21.6 25.3 26.0 21.2 15.8 25.7 40.7 22.4 18.2 17.6 24.1 34.0 18.2 32.9 38.1 31.8 35.7 21.4 22.8 26.6 35.1 32.9 29.6 28.6 24.2 23.1 11.1 21.2 26.4 17.3 23.8 4.7 11.0 14.6 7.6 12.1 7.4 6.4 5.9 7.3 11.4 5.6 5.0 5.3 29.6 8.7 11.1 5.5 5.2 7.1 30.8 30.8 36.3 42.8 26.2 26.9 27.2 27.8 30.3 24.6 44.7 51.2 45.8 92.5 50.4 45.6 14.1 25.5 64.3 62.6 40.1 25.5 56.2 28.2 62.7 287.2 39.4 93.0 0.0 60.1 78.4 37.7 85.7 57.8 25.6 57.5 90.6 44.4 40.5 51.6 600.1 27.9 56.2 27.0 73.1 56.1 34.9 72.9 48.0 37.8 40.4 47.4 38.8 58.6 35.2 26.6 42.2 105.8 64.7 38.3 96.3 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Urothelial cells: 208.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 15.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavorable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavorable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 28.5 22.9 30.7 18.3 32.5 21.4 28.6 40.1 42.6 26.4 21.5 32.3 15.7 19.0 37.3 27.3 23.4 28.0 22.1 28.8 31.7 22.3 17.3 11.8 28.4 17.3 28.6 30.1 38.1 25.4 56.2 29.2 33.1 28.7 26.2 17.4 30.5 23.9 23.1 26.3 35.3 17.1 24.0 23.2 20.9 21.8 13.0 33.9 13.3 21.4 14.2 17.4 25.5 28.8 3.7 15.7 4.8 1.8 5.9 4.0 1.2 23.6 11.5 31.3 30.0 15.7 24.1 23.6 30.9 39.5 28.1 27.3 14.8 18.5 17.8 13.5 29.1 18.9 20.2 23.7 42.7 20.4 28.4 51.7 5.7 38.1 11.3 32.3 12.4 15.2 23.0 36.2 42.8 58.0 36.9 29.8 15.6 12.6 36.8 27.1 15.8 17.3 15.3 22.9 17.2 16.7 32.4 22.4 27.9 25.8 19.9 46.4 18.2 26.3 27.3 30.8 19.4 13.9 18.1 33.9 25.5 27.8 14.7 24.6 16.5 23.6 25.1 37.8 14.0 42.6 3.8 1.8 3.4 3.4 0.8 4.0 2.5 3.8 3.4 1.8 3.7 2.1 3.1 4.8 5.9 0.6 15.7 1.7 1.2 30.7 32.5 40.1 38.8 31.7 22.3 28.6 30.1 28.7 33.9 35.7 17.1 22.2 117.4 69.8 122.3 44.0 38.2 16.0 23.9 22.7 56.9 29.6 6.6 26.6 42.8 62.1 10.7 0.0 35.7 33.5 53.2 138.6 3.5 18.6 19.2 68.3 60.3 44.8 14.9 42.7 79.1 18.5 57.3 11.8 40.8 105.4 42.3 29.6 62.2 4.1 58.4 71.1 106.1 6.0 9.6 91.6 104.9 13.4 31.9 208.0 CSNK1G1 CK1gamma1 ENSG00000169118 "Casein kinase 1 gamma 1" Q9HCP0 15 64165517-64356259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 12 "Early spermatids: 121.0;Late spermatids: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018209 Supported Cytosol NA NA Cytosol "HPA018209: AB_1847278" "unprognostic (9.10e-2)" "unprognostic (8.09e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (3.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.02e-1)" "unprognostic (8.63e-2)" "unprognostic (3.75e-2)" "unprognostic (7.51e-2)" "unprognostic (8.16e-3)" "unprognostic (1.31e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" 7.2 7.8 10.2 11.9 15.1 11.6 8.7 12.2 10.6 8.7 7.4 7.6 11.6 7.0 11.1 9.9 15.7 10.8 7.8 5.6 8.9 7.6 8.6 6.0 8.4 9.6 6.6 4.7 8.5 8.8 10.4 16.1 7.2 7.2 6.8 7.9 10.1 8.2 14.5 6.5 10.4 6.8 11.1 5.3 8.2 6.8 41.3 7.3 11.8 11.5 5.6 11.2 8.3 10.6 4.1 4.1 8.8 5.1 5.3 8.0 2.4 5.1 10.9 7.9 10.2 6.8 9.3 7.2 6.4 6.6 10.9 9.8 8.7 10.1 8.1 3.5 10.1 11.4 11.9 20.6 12.9 12.8 15.4 5.3 7.6 8.7 5.8 7.8 14.0 9.0 8.2 17.2 11.1 15.9 9.5 11.9 8.4 9.2 8.5 9.8 7.1 7.1 4.4 7.4 6.8 5.7 12.0 9.9 6.5 8.8 20.8 12.8 7.8 8.4 5.1 7.4 13.6 8.9 5.5 12.8 9.9 11.9 7.9 7.9 9.8 18.9 6.9 9.2 10.3 6.1 0.9 3.6 5.6 5.7 5.1 8.0 3.6 5.1 4.1 2.7 4.1 5.1 4.7 8.8 5.3 4.3 4.1 3.9 2.4 10.2 15.1 12.2 10.6 8.9 7.6 6.6 4.7 7.2 7.3 26.8 9.9 7.1 8.7 10.3 44.6 6.5 5.1 16.0 13.6 5.2 64.8 5.8 1.7 8.2 121.0 8.4 8.4 0.0 6.1 7.4 8.9 7.9 3.5 4.0 9.4 9.5 21.9 9.2 9.7 209.9 5.8 10.3 6.8 10.0 10.0 6.9 9.1 7.0 9.6 8.7 29.5 6.5 8.5 27.2 18.4 13.7 3.4 7.7 10.3 10.1 CSNK1G2 CK1g2 ENSG00000133275 "Casein kinase 1 gamma 2" P78368 19 1941149-1981338 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 218.1;Late spermatids: 503.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034868, HPA056572" Uncertain Approved Vesicles NA NA Vesicles "HPA034868: AB_10671235, HPA056572: AB_2683178" "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.83e-1)" "unprognostic (2.42e-3)" "unprognostic (6.51e-3)" "unprognostic (2.27e-3)" "unprognostic (1.14e-3)" "unprognostic (2.00e-1)" "unprognostic (9.42e-2)" "unprognostic (5.78e-2)" "unprognostic (4.83e-3)" "unprognostic (4.09e-3)" "unprognostic (7.95e-2)" "unprognostic (4.65e-3)" "unprognostic (5.09e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-2)" 18.7 22.2 24.8 34.9 19.5 38.1 16.7 30.8 28.9 14.1 19.0 18.2 18.9 27.0 16.5 19.0 22.1 16.9 20.4 16.0 23.3 18.3 19.3 17.9 21.8 35.1 17.3 21.2 18.6 27.0 11.4 24.4 16.7 18.7 18.7 8.7 19.7 26.6 16.0 29.0 23.3 22.1 15.1 12.7 39.1 24.1 58.5 17.4 20.6 16.5 18.1 32.2 17.1 17.1 4.0 5.9 11.2 14.1 3.5 4.9 2.3 23.3 12.6 17.5 27.5 6.2 11.6 14.7 14.5 9.6 11.1 13.6 10.3 12.8 14.7 12.2 9.2 6.1 16.9 9.4 17.7 4.9 13.3 20.4 10.4 20.5 17.4 9.9 16.5 26.4 11.5 11.7 11.5 7.4 8.5 13.1 18.4 21.7 50.6 7.3 13.6 32.8 21.8 31.8 6.5 14.2 28.6 11.1 23.8 8.3 24.6 28.3 23.2 11.0 18.1 16.0 6.9 11.5 27.3 15.6 14.0 11.0 29.3 16.8 32.7 17.3 18.0 14.2 15.7 14.6 2.8 4.0 5.0 4.9 6.2 3.5 3.9 3.6 4.2 3.9 4.0 2.9 4.1 11.2 3.5 14.1 5.9 2.5 2.3 24.8 19.5 30.8 28.9 23.3 18.3 17.3 21.2 18.7 17.4 14.9 17.0 12.0 15.7 19.5 44.1 10.1 7.6 13.4 14.8 10.4 39.3 9.9 8.3 15.1 218.1 19.9 22.5 0.0 25.3 17.2 15.8 22.1 29.9 14.0 12.9 23.8 29.2 14.1 17.0 503.0 19.0 20.5 13.5 5.4 20.2 21.3 24.4 16.5 17.7 12.6 37.2 12.9 14.4 15.6 13.1 22.1 15.2 27.3 18.0 28.5 CSNK1G3 ENSG00000151292 "Casein kinase 1 gamma 3" Q9Y6M4 5 123512099-123617045 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Horizontal cells: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027010 Approved NA NA "HPA027010: AB_10602803" "unprognostic (1.28e-1)" "unprognostic (1.88e-1)" "prognostic favorable (9.90e-5)" "unprognostic (1.60e-2)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.92e-3)" "unprognostic (4.92e-1)" "unprognostic (1.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.52e-1)" "unprognostic (1.97e-3)" "unprognostic (4.38e-1)" 20.7 15.0 15.5 21.7 22.7 11.1 37.7 23.7 31.7 18.8 24.0 8.6 11.2 23.5 19.4 18.4 18.8 14.6 17.7 14.0 22.2 18.0 16.2 27.7 29.0 21.8 13.3 17.7 18.7 15.8 18.6 18.1 16.2 16.6 13.2 27.4 9.1 15.3 14.1 15.6 13.4 24.9 18.6 16.1 16.5 18.2 16.4 11.4 17.2 16.2 16.5 17.4 21.9 18.2 13.6 5.3 11.3 5.9 12.7 9.5 5.1 13.1 12.6 19.0 18.0 19.4 21.8 9.4 14.3 17.1 15.8 23.7 11.3 21.1 0.0 18.6 17.1 18.4 9.6 15.2 28.2 27.4 19.8 10.4 9.3 14.7 12.0 17.3 4.8 9.6 18.4 18.4 17.8 33.8 18.9 17.2 6.5 5.2 10.7 13.3 9.1 6.5 6.0 10.7 10.4 8.7 7.3 20.1 12.5 11.8 14.5 16.5 12.0 15.8 10.5 23.1 16.5 13.8 13.7 15.7 23.4 17.6 14.1 15.7 12.0 13.2 11.8 14.0 14.0 15.0 11.3 5.8 2.5 7.1 5.6 9.5 13.6 5.9 6.2 5.3 12.9 6.1 6.4 4.6 12.7 5.9 4.7 7.3 5.1 15.5 22.7 23.7 31.7 22.2 18.0 13.3 17.7 16.6 11.4 20.8 13.1 23.3 20.5 18.3 27.5 18.7 5.1 18.7 12.5 10.4 7.9 7.5 18.3 20.1 6.7 24.5 25.7 0.0 21.9 13.3 21.6 23.4 5.7 20.9 8.5 85.8 31.4 31.9 15.4 9.7 18.4 16.5 15.1 24.4 23.7 25.7 24.4 40.3 18.4 17.0 2.8 0.0 15.5 22.0 52.1 16.4 5.6 27.4 22.3 37.6 CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported Nucleoplasm NA NA Nucleoplasm "CAB020680: , CAB069395: AB_1611912, HPA059206: AB_2683948, HPA061698: AB_2732667" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (5.44e-2)" "unprognostic (8.28e-3)" "unprognostic (3.62e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (4.11e-6)" "unprognostic (4.08e-2)" "unprognostic (3.89e-1)" "unprognostic (6.88e-2)" "unprognostic (1.94e-2)" "unprognostic (1.16e-1)" "unprognostic (8.58e-2)" "unprognostic (1.50e-1)" "unprognostic (4.47e-1)" "unprognostic (9.53e-2)" "unprognostic (7.37e-2)" 21.5 26.7 23.2 20.6 31.3 16.7 24.1 26.3 32.8 22.2 26.1 28.2 19.5 21.9 24.3 15.7 31.9 23.3 17.7 29.2 21.8 21.9 24.5 23.1 18.6 21.9 21.3 22.6 24.9 27.5 27.7 24.6 23.1 29.4 20.7 24.2 19.6 23.8 22.4 58.8 27.0 22.5 23.3 21.3 21.8 26.5 51.6 23.2 30.3 22.4 22.4 25.7 26.2 22.8 19.8 25.4 23.3 27.3 18.7 19.4 15.7 44.4 39.7 36.7 22.6 14.0 24.5 23.8 26.1 26.4 30.3 33.8 40.0 29.2 39.7 16.8 21.5 42.6 34.5 40.3 39.1 43.2 13.9 14.6 53.8 10.6 38.7 24.1 46.7 11.9 22.4 41.4 27.9 77.7 29.7 32.7 34.5 52.8 26.2 27.7 14.7 56.1 16.6 52.5 39.9 27.4 33.4 32.1 32.4 26.1 28.2 38.4 30.6 22.3 43.0 39.7 29.7 28.7 18.3 30.7 32.2 27.6 20.8 38.6 27.2 64.0 39.2 16.1 28.1 32.5 23.3 19.7 22.2 16.1 27.3 19.4 19.8 15.7 15.5 25.4 18.9 16.0 15.0 12.1 18.7 25.2 21.1 16.4 15.7 23.2 31.3 26.3 32.8 21.8 21.9 21.3 22.6 29.4 23.2 59.6 72.9 45.0 31.0 36.5 45.7 53.7 33.1 80.3 85.3 41.8 29.5 35.3 34.9 61.1 104.2 34.8 33.8 0.0 43.6 47.2 34.8 36.9 60.3 26.4 28.9 57.2 33.8 22.1 30.2 104.8 38.0 35.3 13.5 67.7 41.3 34.4 54.4 24.6 34.6 56.2 26.8 51.8 32.5 61.3 54.1 43.8 51.4 32.4 39.1 45.0 CSNK2A2 "CK2alpha', CSNK2A1" ENSG00000070770 "Casein kinase 2 alpha 2" P19784 16 58157907-58197920 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 194.0;Late spermatids: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (9.49e-2)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.40e-5)" "prognostic unfavorable (1.80e-4)" "unprognostic (6.84e-3)" "unprognostic (2.93e-3)" "unprognostic (2.40e-1)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (2.06e-3)" "unprognostic (7.07e-2)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" 22.8 14.5 15.2 15.2 14.2 14.8 33.5 11.1 17.0 20.4 22.2 12.6 15.1 11.7 19.0 21.4 20.2 15.8 18.7 19.7 12.8 11.5 16.2 21.1 20.0 28.7 10.8 13.9 23.9 28.1 34.3 14.4 29.1 11.6 22.0 15.0 12.9 15.6 15.2 25.4 50.5 18.0 18.8 11.2 26.6 21.1 69.1 10.2 44.3 25.9 12.0 18.5 28.9 33.8 8.9 8.0 8.7 14.1 12.8 14.5 11.7 18.5 20.9 16.2 19.3 22.9 32.4 28.6 14.4 22.2 28.7 18.2 39.1 15.9 33.9 20.3 20.2 14.3 21.9 29.1 26.0 36.5 11.2 15.9 18.6 14.0 34.9 35.2 30.0 19.1 31.7 39.0 21.7 38.8 29.2 30.0 30.8 37.4 9.9 17.4 12.9 29.6 24.9 26.0 9.5 24.3 40.4 33.1 17.9 21.3 20.7 13.7 15.6 34.5 16.2 27.5 25.5 10.1 25.2 24.6 19.7 23.4 15.4 19.2 22.7 18.6 48.2 17.5 20.8 18.3 8.7 14.1 7.4 11.9 12.4 13.5 8.9 14.2 11.6 8.0 7.8 14.3 14.5 0.7 12.8 10.8 7.6 10.7 11.7 15.2 14.2 11.1 17.0 12.8 11.5 10.8 13.9 11.6 10.2 11.9 16.1 14.2 9.3 26.3 21.2 19.7 10.2 13.4 3.4 8.7 3.9 13.4 6.6 13.1 194.0 21.7 13.4 23.3 14.7 21.3 13.6 13.7 8.1 16.3 14.8 17.5 16.1 16.0 26.2 237.3 13.3 17.6 11.8 6.4 12.3 21.7 19.9 13.1 18.4 11.5 21.4 12.9 15.5 43.2 38.8 25.3 20.5 15.2 15.1 20.1 CSNK2A3 CSNK2A1P ENSG00000254598 "Casein kinase 2 alpha 3" Q8NEV1 11 11351942-11353357 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" 12 "Cardiomyocytes: 11.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 5.6" "HPA059206, HPA061698" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "HPA059206: AB_2683948, HPA061698: AB_2732667" "unprognostic (3.10e-2)" "unprognostic (3.39e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.82e-2)" "unprognostic (1.60e-1)" "unprognostic (6.25e-4)" "unprognostic (4.36e-2)" "unprognostic (5.42e-2)" "unprognostic (1.88e-1)" "unprognostic (5.46e-3)" "unprognostic (1.07e-1)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.38e-2)" 4.6 1.6 1.3 2.8 1.3 0.6 1.9 1.6 5.5 2.8 3.8 0.5 2.1 3.4 1.8 3.8 3.4 1.1 1.6 2.3 1.5 1.2 5.4 3.0 3.7 1.0 1.1 0.7 2.0 1.4 0.6 1.7 2.9 2.0 2.2 0.7 2.1 1.7 3.6 5.3 1.9 2.9 2.9 1.2 0.9 1.3 3.5 0.3 3.6 1.6 1.8 2.7 1.8 1.3 0.7 0.9 1.1 0.6 0.8 1.0 1.2 5.6 1.2 0.2 2.1 0.0 0.0 0.7 0.5 0.3 0.3 0.3 0.0 0.3 0.0 0.4 0.0 1.6 1.9 1.0 0.8 0.0 0.2 0.3 0.0 0.2 0.5 0.0 0.2 0.4 0.6 0.4 0.0 0.6 0.1 0.0 0.8 0.4 0.8 0.7 0.6 1.3 0.7 1.7 0.4 3.0 0.9 0.2 1.0 0.6 1.0 0.5 1.2 1.6 3.2 0.6 0.2 1.2 0.4 0.7 0.9 1.2 0.4 0.6 0.5 0.9 0.8 2.6 0.2 2.6 0.7 0.5 1.1 0.6 0.6 0.9 0.7 0.4 0.7 0.9 0.7 1.0 0.3 0.1 0.8 0.6 0.7 0.7 1.2 1.3 1.3 1.6 5.5 1.5 1.2 1.1 0.7 2.0 0.3 3.0 0.3 0.0 0.8 1.5 1.0 11.1 0.0 1.4 1.2 3.5 0.0 0.6 0.0 0.7 1.7 1.6 0.4 0.0 0.7 0.4 0.5 1.0 1.1 0.0 0.2 3.2 1.2 0.6 1.0 1.4 0.6 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.6 0.5 0.0 0.7 0.6 0.9 0.9 0.8 0.8 0.4 0.5 DAPK1 "DAPK, ROCO3" ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708633 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 94.7" "Cell type enhanced" "Detected in many" 5 "Alveolar cells type 2: 65.3;Ito cells: 79.2;Kupffer cells: 64.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.3;eosinophil: 6.9;intermediate monocyte: 11.9;myeloid DC: 4.0;non-classical monocyte: 11.7;plasmacytoid DC: 5.3" "Group enriched" "Detected in many" 55 "dendritic cells: 5.3;granulocytes: 6.9;monocytes: 11.9" "Cell line enhanced" "Detected in many" "HMC-1: 38.8;HUVEC TERT2: 22.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB037302, HPA040472, HPA048436" Approved Approved Centrosome NA NA Centrosome "CAB037302: AB_1078622, HPA040472: AB_2677001, HPA048436: AB_2680390" "unprognostic (2.55e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.75e-1)" "unprognostic (1.88e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-2)" "unprognostic (2.77e-3)" "unprognostic (8.31e-3)" "unprognostic (8.76e-2)" "unprognostic (2.40e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-3)" 14.6 4.9 10.4 8.8 25.5 3.8 4.1 2.9 17.6 8.1 16.6 6.5 8.1 7.8 8.7 16.1 4.5 12.2 21.6 4.1 12.4 8.1 14.7 21.3 28.6 8.5 4.6 10.4 32.7 21.2 4.8 16.6 94.7 6.6 5.1 7.5 5.9 9.3 7.3 1.5 3.7 11.0 8.1 4.8 16.4 15.0 6.3 7.3 34.5 7.2 1.5 5.2 13.2 10.5 0.1 5.3 6.9 11.9 0.1 0.1 2.1 0.0 18.3 8.8 6.2 0.2 0.1 14.0 1.2 1.7 7.2 8.2 2.6 0.1 0.1 1.8 0.3 0.1 17.1 5.4 0.4 3.1 0.1 4.4 8.8 2.5 8.9 7.9 0.0 38.8 0.5 2.9 1.3 0.5 11.3 22.0 2.5 6.6 3.7 6.0 0.5 2.6 0.0 10.0 16.9 0.0 0.7 7.8 0.0 20.1 18.3 4.0 4.5 0.0 1.8 7.7 13.5 0.0 5.8 0.1 0.0 0.1 0.0 0.0 14.6 3.0 0.0 0.1 2.4 1.2 1.3 5.3 6.9 0.0 11.9 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 1.6 0.1 11.7 5.3 0.0 2.1 10.4 25.5 2.9 17.6 12.4 8.1 4.6 10.4 6.6 7.3 47.6 65.3 5.9 0.6 3.2 19.8 1.9 40.8 16.0 40.9 21.0 2.0 5.6 1.7 27.2 1.2 13.0 2.1 0.0 20.1 14.4 11.4 3.9 23.1 16.3 21.3 17.5 0.0 79.2 64.1 2.2 13.8 42.1 11.8 30.7 7.7 14.5 31.5 1.7 12.7 5.9 2.9 0.0 2.3 3.9 4.1 2.8 11.9 0.7 2.8 9.3 DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 51.8;skeletal muscle: 46.1" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 80.4;Enterocytes: 44.6;Late spermatids: 59.2" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 19.1;eosinophil: 51.8;neutrophil: 16.4" "Lineage enriched" "Detected in many" 23 "granulocytes: 51.8" "Cell line enhanced" "Detected in many" "ASC diff: 10.1;HaCaT: 8.4;HMC-1: 17.2;MCF7: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" NA NA "Golgi apparatus, Vesicles" "HPA071581: AB_2686421" "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favorable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" 8.2 1.6 2.6 6.8 5.0 10.3 5.2 1.4 3.9 3.6 16.6 12.0 8.3 14.2 1.7 1.5 2.1 1.2 1.7 17.6 3.6 2.0 2.2 1.4 14.0 2.5 6.8 3.0 0.7 1.7 1.1 1.1 0.3 4.7 3.1 4.7 1.9 4.8 4.8 46.1 4.6 25.8 1.2 3.4 4.7 6.9 2.0 6.5 1.1 22.3 8.7 3.3 2.1 9.6 0.3 2.2 51.8 0.0 0.7 0.6 0.3 2.8 2.0 5.7 1.4 10.1 0.4 0.1 1.9 6.1 1.0 1.1 0.9 1.4 0.2 0.6 6.1 3.4 8.4 3.5 0.1 0.6 0.2 0.1 1.1 3.9 0.1 0.1 0.1 17.2 1.1 7.3 0.4 0.2 6.6 0.6 0.1 0.4 0.1 0.7 8.7 0.0 0.3 0.6 2.8 2.0 2.6 0.0 0.3 0.0 2.8 0.4 0.3 0.4 1.1 0.0 1.4 4.8 0.4 0.4 0.8 1.0 1.3 1.6 0.6 0.2 0.0 0.0 2.7 0.2 19.1 0.0 51.8 0.6 0.0 0.2 0.3 0.1 0.5 0.0 0.1 0.0 0.4 16.4 0.7 0.0 2.2 0.0 0.3 2.6 5.0 1.4 3.9 3.6 2.0 6.8 3.0 4.7 6.5 80.4 21.1 2.7 6.6 10.3 0.0 34.6 2.5 2.7 19.4 0.0 0.0 0.1 1.7 7.8 19.1 2.8 44.6 0.0 30.2 0.1 3.1 14.5 15.0 0.8 0.4 4.8 8.1 8.6 1.2 59.2 2.8 1.4 0.0 0.0 13.0 1.6 13.0 28.8 5.3 0.3 0.1 12.9 2.1 0.9 3.4 3.6 0.1 14.9 16.9 10.7 DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028569, HPA064809" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA028569: AB_10794319, HPA064809: AB_2685357" "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favorable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" 18.8 10.2 12.6 16.6 16.4 10.0 17.2 14.5 29.5 22.5 30.1 13.6 11.5 18.5 33.1 11.5 20.2 18.5 21.9 49.2 12.4 11.0 10.9 11.0 24.5 11.6 11.9 16.8 18.8 21.7 11.1 14.6 26.0 19.7 21.3 6.9 18.2 15.3 25.8 45.2 17.8 17.0 38.8 10.6 14.7 23.3 15.7 12.7 11.8 11.4 11.6 12.9 26.7 17.8 15.0 14.7 23.9 15.6 17.3 19.5 11.0 25.7 20.5 12.8 16.1 9.6 10.9 19.8 35.6 28.7 29.1 19.2 37.7 7.8 14.3 17.5 31.2 20.5 20.6 12.5 20.2 10.6 20.9 20.8 5.7 25.1 21.6 30.6 13.8 21.7 24.7 25.3 26.4 15.2 17.5 24.1 9.8 18.1 24.9 17.7 16.8 13.7 10.4 19.9 10.5 16.5 17.2 18.9 13.3 17.5 20.3 20.3 14.1 24.0 28.9 20.4 15.7 20.8 10.9 45.1 37.5 17.0 33.5 44.4 27.8 22.8 16.5 29.8 14.5 19.9 22.1 14.2 23.9 19.5 15.6 14.0 13.5 14.8 17.9 12.6 15.0 11.3 10.8 23.9 17.3 10.6 14.7 17.6 11.0 12.6 16.4 14.5 29.5 12.4 11.0 11.9 16.8 19.7 12.7 23.8 10.9 16.6 82.6 89.4 12.3 27.3 17.8 5.3 7.9 10.4 2.0 40.8 14.9 91.0 24.5 19.4 61.2 0.0 75.9 65.4 32.8 38.1 20.7 6.0 20.1 11.1 26.2 20.3 16.7 17.7 21.0 12.0 35.4 33.3 33.0 11.1 89.1 42.1 21.2 11.5 10.2 32.3 50.1 15.2 15.6 62.7 77.9 17.5 20.3 41.6 DCLK1 "DCAMKL1, DCDC3A, DCLK, KIAA0369" ENSG00000133083 "Doublecortin like kinase 1" O15075 13 35768652-36131306 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 76.5" "Cell type enriched" "Detected in many" 4 "Muller glia cells: 84.2" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.7;ASC TERT1: 15.8;fHDF/TERT166: 12.9;GAMG: 19.8;HAP1: 10.0;HSkMC: 14.6;NTERA-2: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012405, HPA015040, HPA015655" Enhanced Approved Nucleoplasm,Cytosol NA NA 11000 Nucleoplasm Cytosol "CAB012405: , HPA015040: AB_2669141, HPA015655: AB_2669265" "unprognostic (2.29e-1)" "unprognostic (2.56e-1)" "unprognostic (7.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.99e-1)" "unprognostic (2.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (7.72e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (1.93e-3)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-4)" 13.9 3.3 14.3 4.2 25.0 1.1 8.6 8.6 76.5 12.2 3.5 8.6 0.5 2.0 6.4 5.8 5.8 3.3 7.1 5.8 21.9 21.9 1.9 1.2 3.0 4.3 11.9 22.5 6.4 2.1 1.5 7.4 1.1 13.9 4.7 4.4 0.5 2.5 4.7 1.9 4.7 2.7 17.0 10.4 4.6 2.5 2.2 8.5 0.0 2.1 1.4 2.9 5.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 16.7 15.8 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 12.9 19.8 0.0 10.0 0.2 0.0 0.0 0.6 0.0 0.4 0.0 0.6 0.0 0.0 14.6 7.3 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 20.7 0.0 0.2 0.0 1.1 0.0 0.5 0.0 4.1 2.5 0.0 0.0 1.2 6.1 0.0 0.0 0.0 0.0 3.4 4.3 0.7 0.1 0.0 0.0 1.4 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 25.0 8.6 45.8 21.9 21.9 11.9 22.5 13.9 8.5 8.9 1.1 0.0 1.0 13.5 2.2 5.1 0.0 4.0 4.5 3.5 3.9 0.0 0.0 0.0 1.3 2.9 0.0 0.0 0.0 0.0 9.3 0.5 0.0 0.0 0.1 9.5 0.0 0.6 0.3 0.9 19.2 0.0 13.5 0.0 0.0 84.2 0.3 0.0 3.9 0.2 2.1 6.5 16.8 1.6 0.7 8.4 0.0 0.0 0.0 1.3 DCLK2 "DCAMKL2, DCDC3, DCDC3B, DCK2, MGC45428" ENSG00000170390 "Doublecortin like kinase 2" Q8N568 4 150078274-150257457 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 60.5" "Cell type enhanced" "Detected in many" 10 "Bipolar cells: 18.2;Cone photoreceptor cells: 15.7;Horizontal cells: 33.4;Muller glia cells: 39.2" "Cancer enriched" "Detected in many" 17 "glioma: 53.3" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive B-cell: 2.5;plasmacytoid DC: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 18.6;BJ: 8.4;BJ hTERT+: 19.4;fHDF/TERT166: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015770 Enhanced Approved NA NA "HPA015770: AB_1847509" "unprognostic (7.37e-2)" "unprognostic (1.56e-3)" "unprognostic (9.30e-2)" "unprognostic (1.49e-2)" "unprognostic (4.06e-1)" "unprognostic (6.24e-3)" "unprognostic (1.90e-1)" "unprognostic (7.38e-3)" "unprognostic (2.18e-1)" "prognostic favorable (3.25e-4)" "prognostic favorable (2.48e-4)" "unprognostic (6.87e-2)" "unprognostic (3.93e-3)" "unprognostic (3.74e-3)" "unprognostic (4.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.45e-2)" 2.9 3.9 23.3 2.1 23.5 1.6 2.0 9.3 60.5 3.1 2.8 16.5 0.8 2.8 4.3 3.5 3.0 2.8 4.0 14.4 23.5 17.5 2.9 1.8 2.7 1.6 14.9 14.5 4.3 3.5 1.4 4.7 2.9 20.2 3.9 3.5 2.1 2.0 3.6 2.3 2.1 2.7 6.4 23.4 2.1 2.2 4.2 15.9 0.0 4.1 0.0 1.5 3.3 2.0 2.5 1.5 0.0 0.5 0.0 0.0 0.0 0.8 3.2 18.6 2.9 0.0 0.9 0.3 8.4 19.4 2.8 0.6 0.1 0.0 0.0 0.3 8.5 2.8 0.0 2.7 0.0 3.5 3.8 1.6 0.0 4.9 0.0 4.0 0.5 0.5 0.5 0.0 1.7 0.2 1.7 0.9 0.5 0.0 0.0 1.9 0.1 0.3 0.0 0.4 0.2 1.0 0.0 2.1 0.7 0.0 0.8 7.1 6.8 3.5 2.6 0.8 1.6 0.0 0.0 1.6 2.6 1.0 1.7 0.9 0.8 0.0 0.0 2.4 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 23.3 23.5 9.3 19.3 23.5 17.5 14.9 14.5 20.2 15.9 0.0 0.0 0.0 0.1 0.5 18.2 9.1 2.5 0.0 1.2 3.5 15.7 0.0 0.0 0.3 0.0 5.6 0.0 0.0 0.6 0.0 2.2 0.9 4.6 0.0 1.3 33.4 2.9 8.6 0.0 0.0 1.7 1.0 5.0 0.0 0.2 39.2 0.2 0.0 3.5 0.3 8.9 12.9 4.1 0.1 0.2 0.5 0.2 0.0 1.3 0.1 DCLK3 "DCAMKL3, DCDC3C, KIAA1765" ENSG00000163673 "Doublecortin like kinase 3" Q9C098 3 36712422-36764349 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 10.0;testis: 8.0" "Cell type enriched" "Detected in some" 5 "Early spermatids: 24.4" "Cancer enhanced" "Detected in single" "testis cancer: 1.2" "Region enhanced" "Detected in many" "basal ganglia: 10.0" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.4;SCLC-21H: 3.3;SH-SY5Y: 2.7;U-2 OS: 1.9;U-2197: 2.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040685 Approved NA NA "HPA040685: AB_2732487" "unprognostic (9.09e-3)" "unprognostic (1.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.66e-2)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.96e-2)" "unprognostic (1.86e-2)" "unprognostic (2.05e-1)" "unprognostic (7.07e-2)" "unprognostic (6.11e-5)" "unprognostic (7.94e-3)" "unprognostic (5.80e-2)" "unprognostic (3.25e-3)" "unprognostic (1.36e-2)" 1.1 0.4 2.6 1.4 10.0 0.3 0.1 0.1 2.3 0.5 0.2 0.3 0.0 0.5 0.3 0.1 0.1 0.2 0.6 0.9 1.4 0.9 0.0 0.1 0.3 0.2 0.6 0.0 0.0 0.2 0.4 1.8 1.1 0.4 0.3 0.3 1.3 1.7 0.2 2.7 0.4 0.4 0.9 0.7 0.1 0.0 8.0 3.2 0.0 0.9 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.9 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 2.7 0.1 0.3 0.0 0.2 0.0 0.4 0.3 0.0 1.9 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 10.0 0.1 2.3 1.4 0.9 0.6 0.0 0.4 3.2 0.0 0.0 0.0 0.0 0.0 5.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 5.2 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.7 0.2 0.0 0.0 0.0 0.0 0.0 DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Muller glia cells: 145.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 31.8;HBEC3-KT: 24.5;RT4: 32.5;T-47d: 36.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA 2100000 "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favorable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" 6.7 11.3 23.5 7.9 36.2 2.2 12.5 6.8 42.2 9.7 25.2 57.4 17.6 16.8 7.7 10.5 30.5 31.7 18.9 8.7 27.8 20.8 19.8 3.5 13.2 3.1 55.7 19.8 11.3 20.9 28.2 14.6 13.3 34.7 17.7 14.9 4.0 28.3 20.5 9.1 41.3 32.1 3.1 43.2 5.1 52.2 5.1 37.0 8.7 20.9 10.5 7.6 16.3 16.6 1.8 0.4 0.0 0.2 0.0 1.8 0.9 19.7 6.5 9.2 1.9 0.6 0.9 5.7 0.5 0.1 0.3 0.0 8.7 10.5 0.1 11.0 1.7 9.6 31.8 2.0 24.5 0.1 10.9 3.5 0.0 6.0 2.3 1.8 0.0 0.4 1.2 12.7 0.1 0.2 5.8 0.7 0.5 5.7 0.2 1.4 12.5 0.7 0.0 1.6 10.9 1.3 1.3 6.9 0.7 4.7 32.5 1.6 0.9 1.8 14.7 7.1 3.2 36.5 0.2 1.5 4.6 4.3 0.4 4.6 0.2 0.0 0.8 3.0 0.0 4.0 0.0 0.2 0.0 1.1 0.0 0.8 0.4 0.2 0.7 0.4 1.8 1.2 1.8 0.0 0.0 0.0 0.4 0.0 0.9 23.5 36.2 6.8 25.0 27.8 20.8 55.7 19.8 34.7 37.0 32.8 24.0 2.2 62.3 47.2 5.2 19.9 38.2 33.5 31.8 85.5 0.0 53.4 5.0 115.9 10.8 4.9 88.3 23.3 66.9 19.7 6.5 54.7 1.1 0.4 5.4 6.4 44.4 1.8 0.8 16.6 7.8 2.2 15.1 22.6 55.1 145.4 62.4 74.8 4.9 5.6 7.4 6.5 8.9 0.7 4.5 45.4 38.9 0.0 54.4 76.8 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787400 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 8 "Fibroblasts: 84.7;Leydig cells: 58.4;Peritubular cells: 83.1;Smooth muscle cells: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 5 "T-cells: 1.3" "Cell line enhanced" "Detected in many" "ASC diff: 61.7;ASC TERT1: 61.0;BJ hTERT+: 45.1;fHDF/TERT166: 32.3;HSkMC: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Supported "Plasma membrane,Actin filaments" Yes No 850000 "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 42.1 43.5 4.7 10.9 6.9 0.2 15.6 7.9 7.1 30.3 30.4 9.0 18.6 3.3 24.2 17.7 25.0 13.4 16.6 15.4 7.9 4.7 4.0 3.3 8.9 5.1 12.9 3.4 26.4 2.2 2.1 4.0 6.6 12.7 21.8 9.1 30.7 6.4 19.3 5.2 6.1 10.1 34.3 19.7 3.4 14.1 8.3 7.5 0.0 8.6 12.8 4.1 29.0 18.3 0.1 0.2 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.0 16.3 61.7 61.0 0.2 24.0 45.1 10.5 15.1 0.0 0.0 0.0 0.0 32.3 2.1 0.0 0.0 0.1 14.4 12.9 0.1 0.0 0.1 0.0 26.8 0.0 0.0 43.3 0.1 18.5 0.5 17.0 12.1 0.1 0.1 5.1 9.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 6.9 0.1 0.0 0.0 0.0 9.9 0.0 0.0 0.8 0.9 0.0 0.0 0.6 16.8 3.7 8.5 3.3 0.7 1.3 0.0 15.2 0.0 17.0 0.0 0.0 0.0 1.1 0.0 1.3 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 4.7 6.9 7.9 7.1 7.9 4.7 12.9 3.4 12.7 7.5 3.0 2.9 0.0 2.4 11.2 3.1 23.3 2.5 4.0 1.2 0.0 0.0 0.5 0.0 0.5 6.9 21.3 2.0 0.0 1.5 0.4 84.7 4.1 1.1 3.0 1.1 0.0 1.2 24.5 2.1 4.0 58.4 1.5 21.9 0.0 0.7 19.0 1.5 1.7 83.1 0.9 2.9 38.8 68.4 0.9 0.9 7.5 0.8 1.3 0.6 3.3 DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769717-45782552 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 79.6" "Cell type enhanced" "Detected in many" 9 "Sertoli cells: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 44.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007164, HPA008905" Enhanced Approved Vesicles,Cytosol NA NA Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favorable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" 9.0 18.7 5.1 9.7 6.3 1.7 4.9 8.8 6.2 16.5 23.4 4.4 15.6 8.7 21.2 15.0 31.2 13.7 20.3 56.7 5.0 5.3 4.9 2.2 6.5 4.1 4.8 6.5 8.4 33.3 3.1 10.7 6.8 5.6 16.3 3.8 22.0 6.1 19.7 79.6 5.1 11.3 65.1 4.2 5.3 12.0 5.9 4.0 1.1 6.1 36.6 5.0 44.9 8.2 1.5 0.0 0.0 0.8 0.3 2.2 0.0 7.2 10.2 12.1 7.5 8.2 11.5 7.3 16.4 12.1 6.6 6.4 1.2 3.9 2.3 2.5 18.7 5.3 10.7 3.5 1.6 2.5 11.4 10.7 0.9 12.7 1.7 8.0 0.1 4.1 16.6 5.7 5.7 2.8 16.3 3.0 1.2 7.2 5.9 9.5 8.1 1.1 2.8 7.2 3.2 2.2 3.7 44.7 3.8 3.5 8.4 6.5 10.5 8.9 18.8 5.3 6.9 15.4 3.6 9.2 7.7 7.6 7.2 12.0 11.4 9.7 2.3 7.0 1.0 10.7 0.0 0.0 0.0 2.2 0.8 0.5 0.3 0.7 0.2 0.0 1.5 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 5.1 6.3 8.8 6.2 5.0 5.3 4.8 6.5 5.6 4.0 0.0 2.1 0.9 7.0 7.1 4.9 3.1 2.5 0.0 2.3 3.5 7.9 2.3 1.7 2.4 1.4 6.0 3.6 0.0 15.0 1.5 12.7 3.3 0.0 0.9 0.7 4.8 9.7 10.4 1.2 1.4 6.6 0.5 6.8 0.0 5.5 2.2 5.0 3.5 21.9 22.0 7.6 58.2 23.7 6.3 6.0 5.9 1.4 5.0 3.6 3.7 DSTYK "DustyPK, KIAA0472, RIP5, RIPK5" ENSG00000133059 "Dual serine/threonine and tyrosine protein kinase" Q6XUX3 1 205142505-205211566 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Horizontal cells: 84.2;Melanocytes: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044140 Approved Uncertain "Nuclear speckles,Intermediate filaments,Cytosol" NA NA "Nuclear speckles, Intermediate filaments" Cytosol "HPA044140: AB_10965031" "unprognostic (1.42e-2)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (3.26e-2)" "unprognostic (7.80e-2)" "unprognostic (1.93e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (8.73e-5)" 6.4 9.2 13.8 4.4 13.3 19.6 8.2 20.4 16.4 8.4 6.5 6.8 4.2 3.3 10.5 7.4 6.7 9.2 5.4 5.7 10.7 9.0 9.3 2.5 7.3 5.4 8.1 11.8 14.0 5.9 22.0 11.0 7.1 12.2 7.2 4.6 9.2 6.2 8.8 14.6 14.0 4.8 8.8 11.0 7.0 5.3 11.5 9.2 7.1 8.4 3.6 5.3 7.6 6.4 3.5 3.1 9.8 3.5 4.8 5.1 1.6 6.9 4.5 4.9 5.9 7.1 12.0 3.4 8.7 8.7 9.1 6.2 2.0 3.8 5.1 2.6 14.6 5.0 4.9 5.3 5.6 9.3 2.4 5.7 9.3 6.0 2.2 6.4 2.6 5.0 7.0 8.5 9.3 8.9 10.9 6.6 3.7 12.0 3.5 7.2 4.7 2.0 2.3 5.2 1.3 5.4 1.8 8.8 4.5 6.1 4.4 2.7 5.3 7.4 7.7 24.3 5.9 5.6 3.4 6.6 5.7 5.7 8.6 5.7 3.6 2.5 3.0 6.6 3.6 20.3 9.8 3.5 6.0 4.6 2.5 4.3 2.7 3.4 3.8 3.1 3.5 5.1 3.7 5.1 4.8 1.8 2.3 2.0 1.6 13.8 13.3 20.4 16.4 10.7 9.0 8.1 11.8 12.2 9.2 26.8 13.3 11.1 5.8 13.3 46.4 9.5 12.7 29.4 17.0 15.7 31.4 5.9 5.0 10.9 8.6 14.9 3.2 23.3 7.8 4.9 18.1 8.2 23.1 7.4 7.8 84.2 12.2 24.5 20.2 17.3 15.3 13.1 86.0 10.0 5.8 50.7 8.5 3.5 17.0 6.2 34.9 25.8 12.0 20.0 12.7 12.2 2.2 14.9 7.6 5.6 DYRK1A "DYRK, DYRK1, MNBH" ENSG00000157540 "Dual specificity tyrosine phosphorylation regulated kinase 1A" Q13627 21 37365573-37526358 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015323, HPA015810" Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA Cytosol "Nucleoli fibrillar center" "HPA015323: AB_1847922, HPA015810: AB_1847921" "unprognostic (2.71e-1)" "unprognostic (3.35e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-2)" "unprognostic (4.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (9.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (9.95e-2)" "unprognostic (7.39e-2)" "unprognostic (9.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (3.14e-1)" "unprognostic (1.40e-2)" 20.0 18.5 19.2 23.4 20.0 49.7 19.9 31.6 24.6 23.7 23.0 16.3 17.6 15.4 24.4 18.7 16.8 19.4 19.0 23.2 18.8 17.9 16.9 16.1 24.8 27.3 15.5 17.8 25.7 17.8 31.0 25.1 25.0 14.0 17.6 18.1 18.5 18.7 22.7 39.8 20.1 18.7 22.7 13.8 24.1 18.5 23.5 16.3 60.9 22.7 17.4 22.1 22.7 29.3 3.0 3.3 6.0 2.5 1.3 3.8 0.8 10.4 8.1 16.6 11.6 7.9 8.6 14.7 9.3 11.8 9.4 9.9 11.5 9.2 14.0 6.3 16.2 12.4 7.1 12.1 9.0 11.1 21.4 5.2 41.4 13.5 7.0 11.8 16.3 15.2 8.7 10.8 12.2 18.7 10.8 9.7 19.8 15.6 32.5 9.8 10.4 21.4 11.2 17.5 10.3 4.8 27.8 9.1 12.9 9.8 13.6 17.1 9.6 21.1 14.5 14.5 5.8 13.5 15.2 12.4 12.9 3.9 8.0 7.7 22.1 17.1 20.0 10.2 18.4 14.0 5.5 1.5 2.0 3.4 2.1 2.1 2.8 3.6 2.6 1.8 3.0 3.8 3.7 6.0 1.3 2.5 3.3 3.1 0.8 19.2 20.0 31.6 24.6 18.8 17.9 15.5 17.8 14.0 16.3 17.9 21.0 14.9 21.8 33.3 28.8 68.6 17.8 18.7 21.6 10.4 25.5 8.2 0.0 11.5 21.3 24.8 20.2 23.3 12.6 9.6 20.6 24.7 24.3 15.3 13.8 44.5 20.5 28.3 24.3 15.3 15.0 20.8 23.6 6.4 16.5 15.6 16.7 20.4 18.4 8.1 19.4 12.9 24.5 15.8 14.0 27.7 12.8 30.6 13.6 28.3 DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.1" "Group enriched" "Detected in many" 14 "Early spermatids: 145.5;Late spermatids: 469.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028522, HPA028786" Uncertain Supported "Nucleoplasm,Mitotic chromosome" Yes No Nucleoplasm "Mitotic chromosome" "HPA028522: AB_2672656, HPA028786: AB_10670831" "unprognostic (2.22e-2)" "unprognostic (9.86e-2)" "unprognostic (4.55e-2)" "unprognostic (3.45e-3)" "unprognostic (1.96e-1)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.39e-1)" "unprognostic (6.02e-2)" "unprognostic (3.67e-2)" "unprognostic (8.93e-2)" "unprognostic (4.22e-2)" "prognostic favorable (8.83e-4)" "unprognostic (9.73e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-2)" "unprognostic (3.88e-2)" 4.8 7.9 7.4 3.7 10.2 5.0 4.0 10.1 13.1 4.5 4.2 7.4 6.1 6.2 6.4 12.3 6.7 8.0 4.6 9.0 6.6 6.1 6.1 3.2 5.4 5.1 4.4 6.7 6.1 5.2 7.1 12.3 3.8 6.4 5.5 3.4 6.7 5.5 5.8 89.1 6.3 5.1 3.9 3.4 5.9 5.2 28.8 4.6 11.2 6.4 25.3 5.3 5.6 4.1 4.7 8.3 4.8 3.2 6.2 7.0 2.6 0.4 8.6 8.4 5.9 4.8 4.5 0.7 2.7 1.7 2.5 2.3 0.8 3.3 1.3 10.6 3.2 0.1 2.9 1.2 1.9 2.2 4.9 7.3 0.6 5.4 0.8 4.0 0.3 1.8 6.1 1.2 0.8 2.8 8.2 0.6 3.3 1.4 1.9 0.4 4.3 1.9 0.8 2.0 2.5 2.0 0.9 0.1 0.6 5.4 2.1 12.2 13.8 4.2 4.2 0.2 4.7 4.1 0.5 4.2 1.1 1.9 0.9 0.8 3.1 1.0 0.9 7.1 0.8 0.4 1.2 3.1 3.2 5.9 3.2 7.0 4.7 4.0 5.9 3.5 3.5 2.2 3.5 4.8 6.2 2.9 8.3 4.2 2.6 7.4 10.2 10.1 13.1 6.6 6.1 4.4 6.7 6.4 4.6 0.0 1.1 13.7 3.6 3.1 14.9 5.3 5.1 1.4 0.0 15.7 19.6 1.8 8.3 11.7 145.5 5.7 9.1 0.0 3.7 1.5 4.0 5.4 1.1 3.0 4.9 9.5 19.5 6.2 9.2 469.8 6.6 2.7 5.0 3.6 9.4 8.1 8.6 8.6 4.9 11.2 13.0 0.0 2.3 22.4 14.0 2.5 1.1 6.9 8.5 3.2 DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 72.1;Horizontal cells: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA027230: AB_1847925, HPA056902: AB_2683271" "unprognostic (5.86e-3)" "unprognostic (4.18e-1)" "unprognostic (4.08e-3)" "unprognostic (2.56e-3)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (7.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" 12.2 5.3 4.5 20.1 4.8 8.6 8.1 4.4 6.6 10.1 21.3 4.1 8.3 13.7 14.6 9.6 9.6 9.1 16.9 26.1 4.7 3.2 6.3 4.6 10.1 17.9 4.0 3.3 7.6 8.5 3.6 4.4 13.0 5.0 7.1 15.3 6.6 7.2 6.6 23.7 9.4 26.0 11.2 5.3 10.3 14.0 4.4 3.9 34.3 7.6 12.5 17.2 11.1 12.2 2.7 1.9 5.9 1.3 6.9 6.8 1.6 13.8 7.8 11.7 8.4 5.9 8.1 9.4 14.1 9.2 6.9 3.9 10.3 7.7 25.8 17.4 20.3 4.2 16.1 9.3 5.5 7.4 11.1 12.2 4.1 5.2 3.9 2.3 9.4 9.1 6.6 7.9 18.6 14.9 11.7 3.8 11.0 5.1 13.5 8.8 7.9 8.0 4.6 10.1 9.0 12.6 21.5 11.6 11.4 8.0 17.4 15.5 18.3 5.9 7.9 8.1 8.3 5.4 7.9 5.7 11.0 10.4 7.5 11.1 6.5 1.0 14.3 10.5 6.4 11.3 3.2 0.5 5.9 5.2 1.3 4.0 2.7 3.9 6.8 1.9 2.7 3.3 6.1 0.7 6.9 1.3 0.8 3.1 1.6 4.5 4.8 4.4 6.6 4.7 3.2 4.0 3.3 5.0 3.9 8.9 12.2 6.4 9.1 10.1 17.2 33.5 22.9 12.0 10.3 1.8 21.6 2.7 0.0 17.2 0.4 10.5 72.1 0.0 15.8 6.4 18.2 11.3 5.7 4.7 14.1 76.3 23.6 6.2 11.6 1.6 10.6 9.8 8.5 6.4 50.5 15.3 15.6 48.2 12.4 7.5 21.9 12.9 21.1 2.5 8.7 14.2 3.8 21.0 26.7 28.1 DYRK3 "hYAK3-2, RED, REDK" ENSG00000143479 "Dual specificity tyrosine phosphorylation regulated kinase 3" O43781 1 206635536-206684419 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.2" "Cell type enriched" "Detected in many" 6 "Early spermatids: 160.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15 "plasmacytoid DC: 6.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.1" "Cell line enhanced" "Detected in many" "hTERT-HME1: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075041 Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA075041: AB_2686730" "unprognostic (6.51e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-2)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-4)" "unprognostic (2.69e-1)" "unprognostic (3.91e-1)" "unprognostic (2.71e-1)" "unprognostic (2.79e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (9.41e-7)" "unprognostic (2.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (7.62e-3)" 7.1 2.7 4.2 4.2 3.5 6.2 7.7 1.3 2.7 5.6 2.7 2.6 3.7 1.2 7.6 5.1 2.7 6.2 12.8 16.3 6.0 3.4 3.4 7.4 5.0 1.6 2.6 2.0 7.6 5.2 2.8 11.2 1.2 4.6 4.5 1.5 4.1 5.5 3.0 2.1 2.0 2.1 7.5 2.7 1.8 3.7 38.2 3.1 5.1 11.9 3.0 1.7 5.4 7.6 0.0 6.1 0.0 0.1 0.0 0.3 0.0 2.5 3.5 0.8 4.9 8.7 7.8 0.1 8.2 18.1 7.5 9.7 0.2 1.3 3.7 1.2 9.6 13.2 0.7 4.2 6.6 8.0 0.0 2.8 5.4 4.4 0.8 13.8 3.7 3.5 5.5 4.3 12.9 35.7 7.7 5.8 5.7 10.4 0.7 11.5 0.9 8.2 2.1 6.9 0.2 6.5 20.4 2.6 0.0 2.4 0.1 5.0 3.7 7.3 0.3 10.0 1.0 0.9 0.9 4.3 15.7 5.9 7.6 6.8 2.9 1.1 4.4 9.3 4.1 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 4.2 3.5 1.3 2.7 6.0 3.4 2.6 2.0 4.6 3.1 3.0 5.1 0.5 10.3 5.8 0.1 10.3 2.5 13.4 5.7 1.8 9.8 0.0 0.0 3.0 160.9 4.2 0.0 0.0 1.9 0.1 7.3 3.2 0.0 1.1 0.9 0.0 2.4 2.5 1.5 27.7 3.7 1.9 8.5 1.8 0.3 3.0 1.4 0.0 1.8 1.0 7.4 6.5 10.3 17.6 3.4 3.1 0.3 0.0 0.2 3.5 DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562204-4615302 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "testis: 85.9" "Group enriched" "Detected in many" 7 "Early spermatids: 369.7;Late spermatids: 289.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028065, HPA056073" Enhanced Enhanced Vesicles No No Vesicles "HPA028065: AB_10601212, HPA056073: AB_2683028" "unprognostic (2.50e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-3)" "unprognostic (2.62e-1)" "unprognostic (4.07e-3)" "unprognostic (2.03e-2)" "unprognostic (4.69e-2)" "unprognostic (1.29e-1)" "unprognostic (7.13e-2)" "unprognostic (1.22e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (1.86e-1)" "unprognostic (9.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" 1.6 2.1 2.3 2.1 1.8 1.6 2.8 1.9 2.3 2.6 2.1 2.2 2.3 1.7 2.5 9.1 1.6 2.0 1.7 1.7 1.8 1.8 1.9 2.0 2.2 2.5 1.9 2.5 2.2 2.3 2.9 2.7 2.9 2.3 2.3 2.7 2.4 2.3 3.4 1.6 1.9 2.4 2.1 2.7 4.3 1.7 85.9 2.1 1.6 4.3 1.6 2.0 2.4 1.6 7.6 2.7 1.3 5.2 1.1 1.6 1.6 1.9 3.0 3.8 4.1 5.8 7.2 4.6 2.3 4.6 5.3 5.8 0.6 3.1 5.7 0.3 6.5 3.6 4.0 2.9 4.3 4.2 4.3 6.6 4.0 0.8 3.3 16.4 3.4 3.2 4.9 9.2 3.7 12.2 9.9 7.4 6.3 1.6 6.5 4.7 4.0 3.2 8.5 5.2 1.0 1.7 0.7 2.7 2.4 6.4 1.8 0.0 1.5 0.4 2.3 3.3 8.7 1.8 3.1 0.5 6.2 4.9 0.6 2.9 1.9 2.3 3.4 3.3 5.4 3.2 0.6 2.8 1.3 1.0 2.2 1.1 7.6 1.5 1.6 2.7 5.8 1.6 1.6 0.1 1.1 5.2 1.4 1.1 1.6 2.3 1.8 1.9 2.3 1.8 1.8 1.9 2.5 2.3 2.1 11.9 14.4 11.1 13.1 7.9 20.7 19.4 5.1 12.0 13.6 15.7 9.8 12.9 26.6 22.0 369.7 9.3 4.0 0.0 23.8 10.1 17.5 12.6 17.3 9.2 41.7 12.7 5.2 9.2 15.7 289.4 14.1 15.9 15.1 18.0 47.3 16.6 22.1 15.8 29.7 28.1 17.0 6.5 15.6 20.0 31.5 6.6 8.2 17.3 15.6 9.8 EEF2K eEF-2K ENSG00000103319 "Eukaryotic elongation factor 2 kinase" O00418 16 22206282-22288732 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Late spermatids: 60.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 4.0;HMC-1: 4.8;NB-4: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007818, HPA056061" Approved Approved Nucleoplasm NA NA Nucleoplasm "CAB007818: AB_598150, HPA056061: AB_2683021" "unprognostic (4.79e-2)" "unprognostic (6.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.94e-2)" "unprognostic (5.09e-3)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.74e-1)" "unprognostic (8.50e-2)" "unprognostic (2.01e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" 16.8 5.5 5.3 8.6 3.7 7.6 12.4 17.5 4.8 14.3 10.7 1.3 9.4 5.6 13.2 8.3 6.1 8.2 12.5 9.0 3.2 3.3 3.7 5.5 9.2 6.7 2.4 4.9 6.4 8.1 3.3 3.0 6.4 4.9 12.5 4.6 4.4 12.4 20.5 16.2 37.5 5.1 15.5 1.6 6.1 6.4 4.6 3.1 4.0 4.4 11.5 6.7 13.3 14.2 0.7 2.3 2.2 0.9 1.3 1.6 0.1 0.1 0.0 0.0 0.0 1.1 1.3 1.0 0.0 0.0 0.2 0.0 0.7 0.0 1.0 0.4 0.0 0.0 4.0 0.6 0.0 0.0 0.4 0.0 1.6 0.7 2.7 0.0 3.8 4.8 0.0 1.0 0.3 0.3 0.9 0.2 0.2 0.5 3.4 0.0 0.0 0.2 4.1 0.4 1.1 0.0 1.0 2.6 0.7 1.2 0.0 1.0 1.6 0.0 0.0 0.4 0.3 0.6 1.2 1.3 2.4 0.9 3.7 0.1 0.8 0.4 1.1 2.8 2.8 0.4 1.5 0.8 0.6 0.5 0.9 0.7 0.4 0.3 0.2 0.2 0.7 0.7 0.3 2.2 1.3 0.5 2.3 1.6 0.1 5.3 3.7 17.5 4.8 3.2 3.3 2.4 4.9 4.9 3.1 20.8 14.1 9.5 7.8 11.2 47.9 16.2 15.3 18.7 12.5 8.7 13.7 15.1 0.0 4.0 41.4 9.5 8.5 0.0 11.6 10.1 9.3 6.6 28.8 14.5 16.0 1.6 2.9 16.0 11.5 60.9 13.3 8.1 8.5 7.2 10.9 7.7 9.6 25.9 14.9 3.0 19.6 6.5 10.3 0.9 3.6 20.1 6.5 7.5 6.8 3.9 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019021-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 102.3" "Cell type enhanced" "Detected in many" 8 "Cytotrophoblasts: 207.2;Syncytiotrophoblasts: 315.1" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 12 "A-431: 345.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 93000000 "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 16.2 8.4 4.9 7.5 6.8 0.1 39.8 5.1 8.5 13.8 7.8 3.3 10.7 3.6 8.2 11.7 15.6 8.8 8.5 4.8 6.8 2.7 7.6 23.5 14.2 2.3 4.1 3.9 10.4 10.1 1.8 2.1 102.3 5.6 10.9 6.7 9.2 15.4 12.9 10.7 32.5 6.3 15.5 3.5 3.3 7.8 5.5 5.9 3.2 12.8 15.5 8.0 10.2 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 345.9 4.4 1.1 1.5 7.1 4.4 1.2 3.4 4.6 2.1 1.6 0.8 3.7 0.2 0.8 2.9 9.0 13.9 0.0 15.3 2.5 0.1 0.2 0.0 1.9 0.2 1.8 0.0 0.0 2.1 14.0 5.3 28.6 3.1 0.2 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.3 1.3 2.2 0.0 0.6 0.0 2.6 3.7 0.0 1.3 2.9 3.5 0.7 1.2 0.3 0.8 1.0 1.9 0.5 14.9 3.2 0.0 0.3 0.2 2.6 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 6.8 5.1 6.6 6.8 2.7 4.1 3.9 5.6 5.9 89.3 37.5 4.2 67.7 76.2 1.5 7.3 53.5 16.0 59.1 21.0 5.9 207.2 0.0 30.6 4.6 10.9 15.9 23.3 21.0 36.6 45.3 37.8 0.0 77.4 24.2 0.0 4.1 6.7 7.0 2.2 118.8 1.3 16.9 2.8 25.3 106.1 41.7 17.3 125.5 14.0 2.3 77.6 23.1 1.6 2.7 78.5 315.1 0.0 20.0 46.4 EIF2AK1 "HRI, KIAA1369" ENSG00000086232 "Eukaryotic translation initiation factor 2 alpha kinase 1" Q9BQI3 7 6022244-6059230 "Enzymes, Predicted intracellular proteins" "Kinase, Protein synthesis inhibitor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 7 "Cytotrophoblasts: 180.9;Syncytiotrophoblasts: 310.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016496, CAB022082, HPA061675" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB022082: , HPA016496: AB_1848057, HPA061675: AB_2684583" "unprognostic (7.15e-3)" "unprognostic (2.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (6.70e-2)" "unprognostic (9.69e-3)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.36e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-2)" 21.0 38.2 31.7 25.4 32.7 62.8 26.9 23.9 41.1 22.8 34.5 31.0 20.8 26.5 22.6 28.6 28.4 23.4 21.5 40.0 29.9 30.0 32.0 46.3 22.1 23.3 33.3 30.3 23.0 32.4 61.9 25.4 43.9 33.4 26.4 34.9 23.4 46.4 26.3 31.6 28.9 29.9 17.8 35.6 25.4 34.7 16.3 22.6 37.1 29.0 17.4 29.6 22.4 20.1 11.7 7.5 17.4 7.4 10.4 10.6 4.8 41.8 26.4 21.2 32.2 20.3 18.4 27.9 21.6 19.7 19.3 24.5 24.2 28.3 32.8 23.7 23.7 34.7 29.6 27.5 19.7 24.9 20.3 42.2 33.8 28.7 36.4 16.7 28.7 30.9 14.7 24.9 18.2 19.7 20.4 20.5 25.9 54.0 31.7 18.1 41.9 15.7 36.7 26.6 24.4 29.8 34.7 22.3 38.5 24.6 20.5 26.4 47.5 41.5 55.5 18.4 30.9 41.8 35.2 19.6 11.1 41.5 19.5 22.9 32.3 32.2 33.5 22.4 37.9 32.1 10.6 7.4 17.4 9.5 5.9 6.4 11.7 7.4 10.6 7.5 7.7 8.6 7.7 4.1 10.4 6.5 6.6 8.8 4.8 31.7 32.7 23.9 41.1 29.9 30.0 33.3 30.3 33.4 22.6 35.7 43.2 44.9 27.9 21.2 28.0 44.8 43.3 34.8 29.6 41.8 15.7 180.9 56.3 48.3 6.9 22.4 43.3 116.8 39.3 64.2 22.2 37.8 19.7 55.5 47.3 30.2 37.0 20.3 29.0 11.9 31.9 31.4 23.6 59.5 60.3 40.2 46.9 35.1 35.3 51.5 23.0 12.9 17.0 32.5 42.3 19.6 310.3 35.0 47.0 25.5 EIF2AK2 "EIF2AK1, PKR, PPP1R83, PRKR" ENSG00000055332 "Eukaryotic translation initiation factor 2 alpha kinase 2" P19525 2 37099210-37157065 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003845, HPA019795, HPA063893" Approved Enhanced Cytosol NA NA Cytosol "CAB003845: AB_562332, HPA019795: AB_1848060, HPA063893: AB_2685144" "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.77e-3)" "unprognostic (8.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.19e-1)" "unprognostic (3.15e-3)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (4.65e-2)" "unprognostic (5.32e-2)" 25.5 14.2 15.9 16.3 15.5 36.4 13.9 16.4 19.0 14.7 13.7 9.9 9.3 14.5 17.2 21.5 12.1 12.8 15.4 10.7 13.7 19.2 12.2 11.5 13.7 10.7 14.3 15.0 18.7 11.7 19.2 21.1 18.2 17.3 15.0 12.8 10.2 23.0 17.8 7.1 6.7 15.2 16.2 14.0 15.5 14.3 5.1 12.8 14.1 13.6 8.1 10.6 14.8 15.5 8.8 6.9 27.6 10.8 8.6 9.9 3.3 23.3 12.0 7.4 9.3 8.1 11.2 14.6 12.3 17.7 39.0 37.6 13.7 13.9 12.5 16.1 13.5 46.4 13.9 12.7 12.5 17.5 27.4 6.7 13.7 9.1 8.9 8.0 13.0 0.1 9.1 4.9 15.6 11.3 6.8 9.7 5.5 9.5 12.6 8.8 10.4 16.7 6.7 7.7 3.9 8.6 16.9 18.1 6.2 7.3 9.0 8.3 8.8 15.1 11.0 23.7 6.5 5.6 3.7 12.5 15.8 16.8 6.8 19.8 9.3 15.3 0.2 7.6 8.9 13.8 17.1 8.2 11.1 8.9 10.6 9.0 8.8 7.5 8.1 6.9 7.0 6.1 7.5 27.6 8.6 10.8 4.7 9.9 3.3 15.9 15.5 16.4 19.0 13.7 19.2 14.3 15.0 17.3 12.8 62.5 27.7 15.7 36.6 17.3 37.2 25.3 33.1 53.5 58.0 21.0 13.7 40.9 18.3 31.1 1.7 56.2 26.2 0.0 42.4 72.4 35.3 31.0 39.4 15.8 34.3 44.5 14.5 29.4 21.6 2.1 52.9 24.7 20.3 23.4 22.2 48.9 41.0 24.6 79.2 28.5 24.1 38.8 34.2 2.6 3.4 8.8 34.1 30.2 26.2 36.3 EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88627576 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Melanocytes: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 38.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved NA NA "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" 12.7 10.3 7.2 12.3 7.6 18.6 10.7 8.8 6.6 15.8 10.7 6.1 20.9 7.3 9.6 12.4 9.5 8.9 8.5 11.1 5.7 5.5 11.5 15.9 10.4 9.3 7.9 5.0 8.8 36.7 18.5 18.4 14.4 8.3 11.4 12.6 7.3 28.0 20.9 12.7 8.9 10.8 7.0 7.5 11.1 19.0 4.6 7.3 8.7 15.7 6.3 17.3 21.5 19.2 6.6 2.6 1.5 0.7 1.6 2.4 0.6 4.9 3.3 7.2 4.7 13.3 9.3 11.5 7.1 9.2 5.1 7.5 7.4 3.6 38.2 4.3 4.9 7.9 4.5 5.2 4.0 7.5 13.4 3.4 4.1 3.3 7.5 8.3 5.0 9.7 3.5 6.4 4.7 10.2 7.6 5.5 4.5 2.4 13.7 3.9 5.6 4.7 4.0 5.3 9.3 3.8 18.5 10.0 6.8 6.3 9.4 5.6 7.7 4.2 10.9 7.2 9.1 4.0 3.0 4.3 4.4 4.7 9.9 4.4 25.7 12.9 27.0 6.2 4.6 5.9 1.1 0.7 1.5 1.7 0.6 1.9 4.7 1.7 2.4 0.9 6.6 1.5 1.1 0.2 1.6 0.2 2.6 1.4 0.6 7.2 7.6 8.8 6.6 5.7 5.5 7.9 5.0 8.3 7.3 8.9 6.9 11.2 8.5 18.0 6.0 4.8 17.8 4.0 1.2 12.2 7.9 3.7 0.0 3.3 0.1 7.7 8.6 0.0 5.5 5.9 13.0 14.2 1.1 11.3 4.1 1.6 13.1 9.8 5.7 0.4 6.9 6.4 30.4 1.0 26.4 2.9 8.4 8.5 5.3 2.6 1.8 0.0 10.3 2.6 3.4 15.9 5.6 7.5 5.1 12.1 EIF2AK4 "GCN2, KIAA1338" ENSG00000128829 "Eukaryotic translation initiation factor 2 alpha kinase 4" Q9P2K8 15 39934146-40035591 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Activation of host autophagy by virus, Adaptive immunity, Antiviral defense, Cell cycle, Growth arrest, Host-virus interaction, Immunity, Neurogenesis, Stress response, Translation regulation" "Activator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "plasmacytoid DC: 32.9" "Group enriched" "Detected in all" 4 "dendritic cells: 32.9;monocytes: 9.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011811 Approved Approved Cytosol NA NA Cytosol "HPA011811: AB_2668543" "unprognostic (3.10e-1)" "unprognostic (4.78e-3)" "unprognostic (5.97e-2)" "unprognostic (7.18e-2)" "unprognostic (1.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-2)" "unprognostic (7.27e-2)" "unprognostic (2.38e-1)" "unprognostic (1.27e-2)" "unprognostic (6.47e-2)" "unprognostic (2.31e-2)" "unprognostic (5.11e-3)" 20.7 16.5 20.2 19.4 27.3 20.2 36.0 22.4 27.3 16.8 16.3 13.6 17.1 12.2 35.7 17.9 17.8 18.1 19.4 18.2 19.5 20.5 15.4 22.7 22.5 16.6 18.6 14.2 20.1 21.5 20.3 34.7 20.5 17.6 22.0 14.6 17.9 16.7 20.3 20.4 20.7 12.2 24.3 14.6 16.1 16.4 11.5 15.1 17.7 24.1 10.6 15.9 27.0 14.4 5.0 32.9 4.2 9.3 3.8 4.5 2.4 14.0 6.8 12.1 18.2 19.9 33.6 11.5 19.8 22.8 16.3 16.1 9.6 6.1 7.5 10.4 26.9 21.8 15.0 16.1 24.0 22.7 35.3 8.1 15.9 12.5 11.6 17.1 9.6 11.0 26.5 16.5 15.5 27.9 23.0 22.6 15.8 11.7 7.1 32.0 4.7 8.0 13.2 7.4 12.5 15.1 9.7 16.8 12.3 20.2 9.6 6.3 9.7 14.2 8.6 12.3 12.3 12.1 16.6 24.0 21.7 16.5 10.8 12.8 9.8 17.7 2.3 15.2 13.2 30.3 4.2 5.8 4.0 3.6 6.7 3.1 3.5 4.0 4.1 8.4 5.0 4.5 4.2 1.7 3.8 9.3 32.9 2.7 2.4 20.2 27.3 22.4 27.3 19.5 20.5 18.6 14.2 17.6 15.1 14.9 23.6 17.2 22.6 10.6 28.5 28.8 22.9 13.4 26.1 15.7 11.8 29.7 11.6 22.9 1.0 27.0 7.3 0.0 22.0 29.4 26.2 25.6 23.1 20.8 27.4 27.0 13.8 23.4 28.6 2.4 39.1 46.9 30.4 32.5 20.8 31.3 33.9 10.5 37.4 15.1 22.8 45.3 18.6 9.8 29.6 12.7 12.7 15.8 27.6 17.2 EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408892 "Cancer-related genes, Enzymes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 104.4" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 16.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 3.4;naive CD4 T-cell: 6.9;naive CD8 T-cell: 5.1" "Lineage enriched" "Detected in single" 9 "T-cells: 6.9" "Cell line enhanced" "Detected in some" "CACO-2: 10.5;HaCaT: 9.8;HBEC3-KT: 8.0;MCF7: 8.7;NTERA-2: 32.7" "Not detected" "Not detected" CAB026144 Uncertain NA NA 24000000 "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favorable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" 0.4 0.4 0.0 2.0 0.1 0.5 1.2 0.9 0.3 5.7 7.9 0.0 3.3 3.3 0.9 1.4 29.3 1.6 7.9 0.4 0.0 0.0 2.8 10.6 2.9 5.8 0.0 0.0 1.2 2.9 104.4 1.3 5.5 1.1 2.1 0.9 1.3 5.8 3.9 0.3 9.5 12.3 0.4 0.2 0.5 1.8 0.8 0.0 5.1 6.0 16.4 17.2 1.6 11.8 0.0 0.7 0.2 0.1 0.2 6.9 1.6 5.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 10.5 4.2 0.0 0.0 0.0 0.0 9.8 0.0 8.0 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 8.7 0.0 1.1 32.7 5.1 0.0 0.0 0.0 0.0 0.7 4.0 0.1 0.0 0.0 4.9 0.0 2.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 3.4 0.9 0.4 0.0 6.9 5.1 0.2 0.2 0.0 0.7 0.2 1.6 0.0 0.1 0.9 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.1 0.0 5.0 1.8 0.0 0.8 2.5 0.0 3.4 7.0 0.0 1.5 0.0 3.9 16.5 0.0 6.5 0.0 3.7 2.0 0.4 2.1 0.0 7.6 0.4 0.0 1.2 0.0 0.0 7.5 0.6 0.0 0.0 0.0 3.7 0.3 5.1 6.8 0.0 1.1 0.0 0.0 0.0 0.2 1.2 3.1 0.8 0.0 6.0 5.0 EPHA10 "FLJ16103, FLJ33655" ENSG00000183317 "EPH receptor A10" Q5JZY3 1 37713880-37765133 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.6;intestine: 12.6;testis: 24.8" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 86.4;Early spermatids: 49.4;Late spermatids: 147.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 5.2;HDLM-2: 19.6;SCLC-21H: 9.1" HPA027497 Uncertain "Intracellular and membrane" NA NA "HPA027497: AB_10601158" "unprognostic (9.27e-2)" "unprognostic (1.21e-1)" "unprognostic (2.94e-2)" "unprognostic (1.24e-6)" "unprognostic (1.06e-1)" "unprognostic (1.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.40e-1)" "unprognostic (7.06e-3)" "unprognostic (1.50e-1)" "unprognostic (8.81e-5)" "unprognostic (2.55e-2)" "unprognostic (2.97e-2)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 0.4 1.1 5.8 1.7 15.6 0.7 1.9 1.3 10.5 0.6 12.6 3.6 0.2 5.8 0.5 6.8 0.8 1.8 2.1 0.4 4.6 7.4 0.5 0.4 0.5 0.6 3.5 5.0 0.4 5.1 1.1 10.8 0.4 6.4 1.4 10.3 1.6 2.4 0.7 0.4 0.6 7.3 1.0 2.3 0.5 5.3 24.8 2.1 0.0 1.0 0.0 0.5 0.6 0.3 0.4 0.3 1.5 0.3 0.8 0.7 0.1 1.5 1.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.7 2.8 0.0 0.4 0.0 0.3 0.1 0.1 0.0 0.0 19.6 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.7 0.0 1.1 0.0 0.2 0.7 2.1 0.6 0.0 0.0 0.4 0.3 1.7 9.1 0.4 1.1 0.0 0.0 0.2 2.9 0.1 0.0 0.0 1.0 0.1 0.0 1.8 1.2 0.0 0.0 0.0 0.1 1.4 0.2 0.1 0.7 0.1 0.4 0.4 0.3 0.3 0.1 0.4 0.6 0.7 1.5 0.8 0.3 0.3 0.2 0.1 5.8 15.6 1.3 10.5 4.6 7.4 3.5 5.0 6.4 2.1 0.0 0.3 0.0 0.0 0.1 5.0 1.4 0.0 0.0 0.0 0.0 86.4 0.0 0.0 0.4 49.4 0.0 9.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 11.1 18.0 0.0 0.0 147.5 1.7 0.0 0.0 0.0 9.3 0.3 2.1 23.5 0.4 0.0 3.0 0.0 0.0 8.2 2.5 0.0 0.0 0.0 8.3 0.1 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156087 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.2" "Cell type enhanced" "Detected in many" 8 "Basal keratinocytes: 179.7;Suprabasal keratinocytes: 217.2;Urothelial cells: 155.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 115 "plasmacytoid DC: 11.4" "Lineage enriched" "Detected in single" 115 "dendritic cells: 11.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.4;EFO-21: 40.9;PC-3: 48.6;U-251 MG: 49.8;WM-115: 54.6" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 6.7 3.4 1.3 3.1 2.6 0.0 5.2 0.5 2.1 12.1 4.9 1.6 1.9 4.3 7.8 3.8 51.2 4.6 16.7 6.4 1.1 0.8 5.7 8.2 6.6 4.7 2.7 1.3 4.5 10.2 2.2 2.8 8.9 3.4 5.8 2.6 5.4 31.0 2.8 3.4 12.7 13.1 2.7 3.0 2.8 6.8 2.4 1.2 1.2 5.7 21.8 25.5 15.2 18.5 0.0 11.4 0.0 0.0 0.0 0.0 0.0 15.6 31.7 8.8 4.2 0.6 0.7 5.2 9.5 13.4 17.2 10.9 13.2 42.4 0.0 40.9 5.4 21.3 6.4 2.1 21.9 6.0 0.0 1.4 0.0 9.2 8.4 11.3 0.0 0.0 1.0 8.2 9.3 20.7 27.0 18.3 0.0 0.0 0.0 10.9 5.0 0.0 0.0 4.2 11.8 48.6 0.0 8.0 0.0 18.2 8.1 0.0 1.3 18.4 4.5 1.2 4.8 0.6 0.1 22.6 6.1 16.5 0.4 49.8 0.0 0.1 0.1 4.7 0.0 54.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 1.3 2.6 0.5 2.1 1.1 0.8 2.7 1.3 3.4 1.2 50.6 28.9 0.5 100.5 179.7 0.6 5.8 40.8 37.5 33.0 8.7 3.9 8.1 0.0 31.3 5.4 17.5 57.1 0.0 12.5 0.9 7.0 56.8 5.7 19.8 1.6 0.0 2.9 32.5 2.8 0.0 3.1 4.6 25.3 1.8 19.6 5.8 62.9 20.1 0.0 1.4 2.0 32.3 17.6 0.0 0.7 217.2 6.3 0.0 17.7 155.0 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107524-89482134 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 39.0" "Group enriched" "Detected in some" 5 "Fibroblasts: 12.2;Horizontal cells: 19.1;Peritubular cells: 7.8;Rod photoreceptor cells: 16.9;Sertoli cells: 6.5;Smooth muscle cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 66.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 9.7 1.1 2.3 1.7 4.5 0.2 5.1 1.3 8.7 12.3 5.8 0.6 1.4 2.2 13.9 1.3 6.3 2.6 17.2 10.0 2.2 2.5 1.5 4.4 2.7 3.0 2.5 3.4 4.2 2.8 1.2 3.4 17.5 11.9 39.0 5.9 5.4 3.8 6.8 1.7 1.7 3.5 17.3 2.9 1.2 3.7 1.3 2.0 0.0 16.3 6.0 3.0 11.8 12.2 0.3 0.1 0.5 0.1 0.3 0.2 0.0 0.0 0.0 66.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 3.8 0.0 0.2 0.0 0.8 0.0 0.0 4.1 0.0 0.0 0.6 0.7 0.0 1.3 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.8 0.0 0.0 0.0 0.6 0.0 0.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.3 0.1 0.1 0.0 0.0 2.3 4.5 1.3 8.7 2.2 2.5 2.5 3.4 11.9 2.0 0.0 0.0 0.0 0.3 0.5 1.5 2.1 0.0 0.0 0.0 0.0 2.0 0.2 0.0 0.0 1.3 1.1 0.0 0.0 0.0 0.1 12.2 0.1 0.0 0.0 0.1 19.1 0.0 0.6 0.0 1.3 2.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 7.8 0.0 16.9 6.5 20.6 0.0 0.0 0.3 0.5 0.0 0.0 0.0 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.6" "Cell type enhanced" "Detected in many" 6 "Cardiomyocytes: 25.0;Pancreatic endocrine cells: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 3.0;gdT-cell: 3.4;MAIT T-cell: 3.4;memory B-cell: 2.5;memory CD4 T-cell: 5.0;memory CD8 T-cell: 3.3;naive B-cell: 1.8;naive CD4 T-cell: 1.9;NK-cell: 6.0;T-reg: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 35.8;ASC diff: 15.8;CACO-2: 26.2;U-2197: 17.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB028368 Enhanced NA NA 8400000 "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favorable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.1 1.8 8.1 1.9 18.3 3.5 5.2 14.7 29.6 4.9 5.9 3.1 3.2 1.1 6.5 3.1 5.0 6.6 3.3 16.7 19.9 4.4 5.2 0.9 3.7 2.5 2.4 16.4 11.7 1.2 2.0 1.2 1.7 4.9 5.9 4.7 0.8 3.7 6.7 3.1 12.8 4.1 8.2 2.1 3.3 4.0 11.4 2.6 0.5 9.8 3.7 3.2 4.6 4.9 2.5 0.2 3.0 0.0 6.0 5.0 0.7 1.1 1.1 35.8 0.0 15.8 9.8 0.0 8.5 3.7 7.7 2.8 26.2 0.4 0.0 0.0 11.8 0.0 3.1 5.5 0.0 3.2 4.2 3.0 0.0 0.3 0.0 0.4 0.0 0.6 3.9 1.9 2.4 0.0 4.8 7.2 0.0 0.0 0.0 2.0 4.2 0.1 0.0 2.5 2.6 0.8 0.0 3.9 0.0 12.0 1.9 6.3 0.0 2.8 0.6 0.6 3.0 1.3 0.0 0.0 0.8 1.5 17.5 0.4 0.0 0.0 0.0 3.2 0.0 1.6 3.0 0.0 0.0 3.4 0.0 3.4 2.5 5.0 3.3 0.0 1.8 1.9 0.3 0.2 6.0 0.0 0.2 2.1 0.7 8.1 18.3 14.7 29.6 19.9 4.4 2.4 16.4 4.9 2.6 0.0 5.4 0.8 0.4 5.5 10.2 25.0 7.6 1.4 3.4 8.7 0.0 0.0 6.6 0.2 2.0 11.7 0.1 0.0 0.2 0.0 3.9 1.2 1.1 0.0 0.3 1.6 3.4 12.3 0.0 4.3 1.1 0.2 6.8 0.0 14.0 6.3 18.0 0.0 8.1 1.5 2.7 0.0 7.2 6.7 1.3 10.9 0.0 1.0 6.8 1.8 EPHA5 "CEK7, EHK1, Hek7, TYRO4" ENSG00000145242 "EPH receptor A5" P54756 4 65319563-65670495 "Enzymes, Predicted membrane proteins" Neurogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.5" "Cell type enhanced" "Detected in some" 14 "Early spermatids: 12.1;Late spermatids: 12.5;Muller glia cells: 6.4" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 7.8;PC-3: 7.1;TIME: 9.5;U-138 MG: 19.9;U-2197: 12.1;U-251 MG: 15.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "unprognostic (1.02e-2)" "unprognostic (4.22e-2)" "unprognostic (2.38e-1)" "unprognostic (4.89e-4)" "unprognostic (7.43e-4)" "unprognostic (1.60e-1)" "unprognostic (6.68e-3)" "unprognostic (2.49e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (9.25e-2)" "unprognostic (5.88e-3)" "unprognostic (2.55e-2)" "unprognostic (5.97e-4)" "unprognostic (3.81e-3)" 0.9 2.7 17.6 1.0 9.0 0.8 0.8 1.9 25.5 5.9 1.2 1.5 1.8 0.9 1.9 0.9 1.1 1.0 0.9 2.7 17.3 6.8 0.9 0.8 1.1 0.9 5.4 13.2 6.2 0.8 0.8 6.5 2.7 10.2 4.2 1.1 2.6 1.2 4.1 0.8 1.2 0.9 1.4 17.7 1.5 1.1 2.2 0.7 0.0 3.0 0.0 0.8 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.3 0.0 0.3 0.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 3.3 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.8 0.2 0.0 0.0 1.2 1.9 0.0 0.0 0.0 0.0 0.0 7.1 0.0 2.2 0.4 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.0 0.0 0.0 9.5 19.9 2.5 12.1 15.3 0.0 0.0 0.0 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 9.0 1.9 24.7 17.3 6.8 5.4 13.2 10.2 0.7 0.0 0.0 0.0 0.0 0.5 0.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.1 1.6 0.0 0.0 0.0 12.5 0.9 0.0 3.3 0.0 0.0 6.4 0.0 0.0 0.0 0.0 1.4 0.0 0.4 1.0 0.2 0.1 0.0 0.0 0.0 0.0 EPHA6 FLJ35246 ENSG00000080224 "EPH receptor A6" Q9UF33 3 96814581-97752460 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;ovary: 13.2;testis: 15.5" "Group enriched" "Detected in some" 67 "Early spermatids: 305.1;Late spermatids: 156.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HEK 293: 8.2;U-266/70: 24.9" "Low region specificity" "Detected in many" "HPA007397, HPA058047" Uncertain Enhanced Nucleoplasm NA NA Nucleoplasm "HPA007397: AB_2667821, HPA058047: AB_2683588" "unprognostic (9.87e-2)" "unprognostic (1.67e-2)" "unprognostic (3.42e-4)" "unprognostic (7.21e-5)" "unprognostic (8.51e-2)" "unprognostic (1.32e-1)" "unprognostic (1.82e-2)" "unprognostic (3.14e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.71e-4)" "unprognostic (1.93e-3)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (7.14e-3)" 0.8 0.5 8.7 0.5 9.8 0.3 0.8 27.9 9.9 2.2 5.8 1.1 0.3 0.6 2.2 1.0 2.1 4.2 2.1 1.1 15.4 1.3 1.3 0.5 0.5 0.4 1.1 6.8 13.2 1.4 0.7 0.6 0.5 5.7 2.5 1.8 0.2 0.6 1.7 0.4 0.5 1.1 3.2 0.8 0.4 1.7 15.5 2.8 0.0 4.3 0.0 0.5 2.1 1.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 8.2 0.0 2.1 0.0 0.0 2.0 0.0 0.0 0.4 0.0 0.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 2.1 0.0 0.8 24.9 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 9.8 27.9 9.9 15.4 1.3 1.1 6.8 5.7 2.8 0.0 0.0 0.0 0.1 0.2 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 305.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 156.3 2.8 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.4 0.6 0.2 0.0 0.1 3.4 2.3 0.0 0.1 0.0 0.0 0.0 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419547 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 110.4" "Group enriched" "Detected in some" 4 "Bipolar cells: 14.1;Cardiomyocytes: 10.8;Early spermatids: 3.7;Horizontal cells: 11.1;Proximal tubular cells: 11.5" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 8.9;HEK 293: 25.5;RH-30: 24.4;THP-1: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" NA NA 340000 "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 1.3 1.3 6.0 1.7 24.6 1.2 2.2 21.6 8.6 2.4 24.6 0.0 0.1 2.5 2.0 7.5 14.7 1.7 3.1 4.2 13.8 2.9 6.9 1.3 1.5 1.3 2.4 5.8 3.0 1.3 110.4 5.6 1.6 6.7 17.9 3.6 0.4 8.2 1.9 1.3 1.4 6.5 20.2 4.8 4.7 14.9 2.1 4.4 0.0 1.3 0.0 1.3 9.7 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 25.5 0.0 2.5 0.0 0.0 0.0 0.0 0.3 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.5 0.0 0.6 4.5 24.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 20.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.0 24.6 21.6 8.6 13.8 2.9 2.4 5.8 6.7 4.4 0.0 0.0 0.0 0.4 0.3 14.1 10.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 3.7 0.7 0.0 0.0 0.0 0.0 2.3 0.3 0.0 0.0 0.1 11.1 0.0 0.0 0.0 2.1 0.9 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 11.5 0.9 0.0 0.8 0.2 0.7 0.9 0.0 0.0 0.0 0.0 EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563564-22603594 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 9.4;brain: 5.3;lymphoid tissue: 10.3;pancreas: 8.3;testis: 3.5" "Cell type enhanced" "Detected in some" 15 "Bipolar cells: 5.2;Early spermatids: 2.5;Horizontal cells: 3.2;Late spermatids: 3.9;Rod photoreceptor cells: 8.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "SCLC-21H: 37.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 25.0" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" NA NA "CAB009660: AB_2099696, HPA031433: AB_10601371" "unprognostic (8.58e-2)" "unprognostic (8.59e-2)" "unprognostic (3.72e-1)" "unprognostic (1.15e-2)" "unprognostic (4.69e-4)" "unprognostic (3.58e-1)" "unprognostic (7.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (9.84e-14)" "unprognostic (2.14e-3)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.68e-2)" 0.2 9.4 1.6 0.2 3.1 0.2 0.1 1.8 3.9 0.2 0.2 2.2 0.0 1.7 0.1 0.3 0.2 0.1 0.2 0.2 2.0 2.6 0.1 0.1 0.2 0.2 2.1 4.1 0.1 8.3 0.2 1.7 0.1 5.3 0.2 0.2 1.6 0.8 0.2 0.3 0.4 0.2 0.1 1.3 10.3 0.2 3.5 0.6 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.3 3.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 3.1 1.8 3.9 2.0 2.6 2.1 4.1 5.3 0.6 0.0 0.0 0.0 0.0 0.0 5.2 0.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.4 0.0 8.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 74.7" "Cell type enhanced" "Detected in some" 14 "Cone photoreceptor cells: 9.8;Early spermatids: 30.2;Late spermatids: 26.8;Muller glia cells: 16.2" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Region enhanced" "Detected in all" "cerebellum: 74.7" "Group enriched" "Detected in some" 33 "neutrophil: 15.9;plasmacytoid DC: 15.4" "Group enriched" "Detected in many" 33 "dendritic cells: 15.4;granulocytes: 15.9" "Group enriched" "Detected in some" 4 "HDLM-2: 34.7;HMC-1: 20.6;RPTEC TERT1: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: AB_2685895" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 2.0 1.5 9.0 1.8 16.6 1.5 5.5 74.7 23.6 3.6 3.4 3.4 3.1 2.8 4.1 2.0 3.8 2.8 3.3 1.1 9.4 5.3 2.3 2.9 1.0 3.3 2.8 7.0 1.7 1.1 0.6 3.8 0.9 7.1 3.3 1.4 1.9 3.9 5.1 7.4 6.0 1.7 1.7 6.0 3.4 1.3 16.7 6.0 0.0 11.6 2.9 3.3 4.5 2.6 0.0 15.4 15.9 0.0 0.0 0.4 0.1 0.0 0.0 4.8 0.0 0.1 0.0 0.1 3.6 0.0 0.2 0.0 0.0 0.0 0.6 1.0 1.9 0.3 0.0 3.2 0.0 0.7 34.7 0.4 2.6 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.2 2.6 0.1 0.1 0.1 1.4 0.6 0.0 0.0 0.5 0.1 9.4 0.0 0.6 0.1 0.0 0.0 0.0 0.7 0.1 0.4 0.2 0.6 2.0 0.3 4.3 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 15.4 0.0 0.1 9.0 16.6 74.7 19.0 9.4 5.3 2.8 7.0 7.1 6.0 0.0 0.0 0.9 0.0 3.3 1.2 1.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.8 30.2 0.6 0.0 0.0 0.3 0.0 0.2 0.1 0.0 5.8 0.4 0.0 0.0 0.0 0.0 26.8 0.6 0.0 1.7 0.0 0.0 16.2 0.6 0.0 0.0 0.0 0.9 0.0 0.8 0.4 0.9 5.1 0.0 0.0 0.0 0.1 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.0" "Cell type enhanced" "Detected in many" 11 "Ductal cells: 42.3;Intestinal endocrine cells: 46.8;Mucus-secreting cells: 53.6;Pancreatic endocrine cells: 38.4;Undifferentiated cells: 82.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "classical monocyte: 2.5;intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "GAMG: 34.4;HUVEC TERT2: 29.7;TIME: 29.4;U-251 MG: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 290000 "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.7 2.9 3.4 15.4 5.4 0.9 2.5 1.9 8.2 3.8 23.9 16.2 4.6 21.6 2.5 3.2 1.1 5.4 4.4 5.4 5.6 6.5 3.5 1.1 3.0 5.5 12.7 3.8 17.9 5.4 6.1 5.4 12.0 8.2 3.3 25.0 2.2 6.6 4.0 0.7 1.8 22.6 4.0 12.1 3.3 2.3 2.9 9.3 0.1 8.4 1.0 2.1 5.3 3.3 0.1 0.6 0.3 2.5 0.1 0.1 0.4 15.9 6.7 6.5 10.4 0.6 0.6 0.0 3.7 0.2 11.3 2.4 2.3 6.4 0.2 8.0 1.6 34.4 15.1 4.4 21.7 3.0 0.0 1.6 0.0 0.7 0.0 6.8 0.0 1.6 2.2 7.0 20.2 0.1 10.0 29.7 0.9 0.6 0.0 2.2 2.3 0.3 0.1 1.5 17.8 4.4 1.9 6.7 0.3 5.5 1.5 7.1 7.4 6.5 0.2 0.0 0.6 0.4 0.2 29.4 4.5 11.8 11.4 25.5 0.0 0.1 0.0 8.4 0.3 0.1 0.3 2.5 0.1 0.1 2.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.4 3.4 5.4 1.9 8.2 5.6 6.5 12.7 3.8 8.2 9.3 3.0 0.0 0.0 1.5 0.7 11.6 1.2 12.7 1.4 3.4 0.0 0.0 0.4 0.0 42.3 2.3 0.5 6.8 0.0 6.8 2.2 1.5 1.4 0.0 0.5 9.1 6.4 46.8 0.6 7.5 0.4 0.9 3.7 0.0 0.0 53.6 20.9 38.4 3.5 0.7 0.0 1.7 0.0 1.7 0.5 2.6 0.4 0.9 0.0 82.9 1.0 EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561784-184582409 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 49.3" "Cell type enhanced" "Detected in many" 10 "Intestinal endocrine cells: 68.8;Mucus-secreting cells: 39.5;Suprabasal keratinocytes: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.1;myeloid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;monocytes: 1.1" "Cell line enhanced" "Detected in many" "BEWO: 17.0;HaCaT: 23.4;OE19: 16.1;SK-BR-3: 18.1;T-47d: 12.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced NA NA 20000 "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" 1.4 0.9 4.5 5.0 2.6 0.5 9.0 9.7 5.7 22.7 8.8 2.3 1.7 5.7 10.0 1.9 19.9 3.0 9.7 1.6 4.7 1.8 1.7 1.0 4.7 1.0 3.3 3.7 9.0 49.3 1.1 1.7 6.3 7.2 7.7 9.7 3.8 27.7 3.5 0.7 32.3 5.6 3.5 1.3 1.2 16.0 1.1 4.0 0.2 1.0 15.7 8.4 4.0 13.6 0.0 3.1 0.3 1.1 0.0 0.4 0.4 3.7 1.3 8.8 0.9 2.7 0.2 17.0 0.6 1.1 1.3 0.7 1.2 0.1 0.0 1.7 3.6 0.6 23.4 3.1 1.1 0.3 0.1 0.7 0.0 0.2 0.0 0.2 0.0 0.2 0.7 7.7 1.0 0.1 0.4 0.0 0.0 0.0 0.0 0.6 9.9 0.0 3.8 0.9 16.1 1.4 0.8 5.3 0.0 0.0 3.4 1.1 1.3 0.7 18.1 0.8 4.8 12.0 0.1 0.0 2.1 3.1 1.1 1.4 0.0 0.0 0.1 0.2 0.0 8.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.1 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.4 4.5 2.6 9.7 5.7 4.7 1.8 3.3 3.7 7.2 4.0 3.0 2.4 0.0 6.9 21.4 0.0 1.4 2.5 1.4 2.3 0.0 0.0 8.1 1.7 0.3 0.4 0.6 3.5 0.0 1.4 14.8 8.4 5.5 4.6 0.0 17.9 14.3 68.8 3.1 0.3 0.0 2.6 1.0 0.0 1.0 39.5 0.1 2.4 7.0 5.6 0.1 0.8 0.0 2.1 0.5 0.6 31.2 13.6 0.0 27.1 19.5 EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827521 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 50.1;Endothelial cells: 43.5;Ito cells: 106.8;Syncytiotrophoblasts: 172.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "classical monocyte: 3.6;neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013537 Uncertain NA NA 1000000 "CAB013537: " "prognostic unfavorable (8.56e-4)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (9.51e-3)" "unprognostic (6.63e-2)" "unprognostic (3.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (8.84e-4)" 14.0 20.7 1.8 4.2 2.9 2.2 17.1 1.9 3.0 29.1 9.5 2.9 14.6 4.1 28.8 10.3 11.0 13.1 35.0 19.0 3.4 1.1 16.8 29.8 16.5 12.0 2.2 0.9 24.6 11.6 5.6 3.1 35.5 3.2 13.7 5.4 11.6 10.8 14.7 5.1 14.2 7.0 12.4 2.2 50.5 8.6 12.2 2.1 2.3 10.2 13.1 7.0 7.7 21.5 0.0 1.6 7.4 3.6 0.0 0.0 1.2 12.6 11.2 11.2 32.6 7.2 4.6 33.3 5.0 10.8 7.8 10.2 9.2 9.7 1.6 22.7 5.1 10.9 13.2 4.9 13.1 4.1 2.1 9.1 0.4 6.5 14.3 4.2 0.2 0.3 5.4 19.7 4.9 11.6 8.6 29.1 0.5 23.9 0.6 6.3 22.1 0.2 4.9 19.2 18.7 16.9 17.2 5.5 2.9 9.9 6.7 0.0 9.7 7.6 3.6 7.4 16.3 9.0 2.2 24.4 9.7 15.4 17.9 7.3 0.1 0.2 0.5 1.4 4.1 17.6 0.0 3.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 7.4 0.0 0.2 0.3 0.0 1.2 1.8 2.9 1.9 3.0 3.4 1.1 2.2 0.9 3.2 2.1 8.9 13.0 6.4 8.7 18.2 0.0 3.6 10.2 1.4 5.7 5.2 0.0 50.1 0.0 9.9 20.9 43.5 2.4 0.0 5.7 7.3 7.4 8.7 1.1 18.1 8.1 0.0 2.9 106.8 5.6 8.1 7.5 1.1 3.3 1.0 14.8 1.5 17.1 7.0 3.9 3.7 0.0 6.5 5.0 1.0 12.4 15.6 172.7 1.7 17.9 7.1 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Collecting duct cells: 129.1;Enterocytes: 93.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 8.8" "Lineage enriched" "Detected in many" 4 "T-cells: 8.8" "Group enriched" "Detected in many" 41 "OE19: 366.2;SK-BR-3: 179.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 430000 "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavorable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favorable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 5.8 2.4 5.2 10.4 7.0 0.1 20.1 4.2 7.0 19.1 46.5 9.1 55.2 21.6 14.9 18.7 40.9 22.7 26.6 24.8 6.3 3.1 37.5 21.5 17.6 3.7 5.1 5.6 19.3 16.2 27.7 8.1 60.8 7.5 23.6 16.6 15.9 28.7 58.1 8.9 35.3 47.2 10.9 4.5 4.0 17.1 6.5 3.7 2.8 35.7 20.8 22.9 19.7 20.3 1.3 0.3 2.1 0.4 0.9 8.8 2.2 2.1 2.5 2.9 1.8 3.5 2.4 3.9 1.5 2.5 3.3 2.8 1.9 5.8 0.1 3.1 3.5 1.8 6.7 0.1 3.4 1.5 0.2 2.2 0.1 2.0 3.1 2.0 0.0 0.0 2.4 3.2 2.0 1.2 3.2 1.3 0.1 0.3 0.1 2.4 3.3 0.3 0.1 5.2 366.2 0.6 0.2 1.1 0.3 3.4 6.7 0.5 0.1 2.9 179.8 0.9 3.7 5.0 0.1 0.1 1.7 2.2 2.1 0.9 0.3 0.1 0.1 0.1 0.0 5.6 1.6 0.4 0.8 8.8 0.3 0.7 0.9 0.5 2.5 0.3 1.3 1.0 2.5 2.1 0.9 0.2 0.2 0.4 2.2 5.2 7.0 4.2 7.0 6.3 3.1 5.1 5.6 7.5 3.7 38.7 34.4 1.3 21.0 12.5 4.3 13.5 30.6 10.7 15.9 129.1 11.8 9.7 6.6 27.1 0.3 4.6 93.2 0.0 22.3 75.4 11.0 33.4 0.0 10.4 3.5 6.4 15.0 12.3 2.4 0.7 17.0 1.8 10.1 1.0 56.6 30.9 26.2 42.1 21.5 20.7 5.9 0.0 10.3 7.1 5.3 16.6 19.0 2.2 63.0 28.1 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Cholangiocytes: 180.9;Enterocytes: 163.1;Paneth cells: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "basophil: 5.3" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.3" "Cell line enhanced" "Detected in many" "Hep G2: 30.9;MCF7: 20.2;OE19: 31.8;RT4: 24.2;SK-BR-3: 28.4;SK-MEL-30: 37.9;T-47d: 31.5;WM-115: 40.2" "Low region specificity" "Detected in many" "CAB025331, HPA045396" Uncertain Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 420000 "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312" "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 1.1 1.4 11.6 12.6 16.5 0.6 26.8 2.0 16.7 6.8 40.5 40.3 12.0 37.7 2.8 7.5 29.4 5.7 22.9 3.4 18.6 9.0 16.5 33.9 13.4 0.5 23.5 9.3 0.9 21.5 11.4 1.0 15.4 14.9 16.8 29.7 5.5 36.8 22.3 1.1 30.7 41.3 3.2 27.4 0.5 32.9 1.2 23.8 0.0 4.5 7.4 8.5 11.8 14.4 0.9 0.7 5.3 0.6 1.2 1.2 0.2 10.0 0.6 0.8 0.3 0.0 0.0 16.4 0.8 1.9 1.1 1.1 5.5 18.2 0.0 0.2 0.2 0.1 8.6 1.2 1.9 0.6 0.2 0.8 0.0 0.3 30.9 0.0 0.0 0.1 0.4 2.5 0.2 0.0 0.2 0.0 0.1 0.7 0.3 0.1 20.2 0.1 0.3 2.8 31.8 0.4 0.1 1.9 0.5 2.1 24.2 0.9 0.3 0.7 28.4 37.9 2.7 31.5 0.1 0.0 0.1 1.1 0.6 0.1 0.2 0.1 0.1 0.1 0.0 40.2 5.3 0.4 0.8 0.9 0.4 0.4 0.4 0.7 0.3 0.3 0.9 0.6 1.2 3.3 1.2 0.6 0.7 0.8 0.2 11.6 16.5 2.0 16.7 18.6 9.0 23.5 9.3 14.9 23.8 110.2 61.2 1.3 13.0 16.3 1.5 1.4 180.9 21.4 61.4 33.2 2.0 44.4 1.7 41.9 0.9 2.2 163.1 0.0 77.1 73.6 2.7 83.4 1.1 83.9 5.5 0.0 89.5 6.7 1.9 0.0 1.4 1.7 52.3 2.8 134.3 11.3 75.9 165.5 0.0 31.8 1.1 6.5 1.7 2.4 2.3 32.2 84.1 1.5 124.3 62.5 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease mutation, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.5" "Cell type enhanced" "Detected in many" 10 "Bipolar cells: 11.2;Cardiomyocytes: 15.3;Ciliated cells: 26.8;Club cells: 17.0;Collecting duct cells: 12.2;Muller glia cells: 12.4" "Cancer enhanced" "Detected in many" "breast cancer: 4.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.6;EFO-21: 7.2;HEK 293: 5.3;RPTEC TERT1: 7.8;SCLC-21H: 4.4;T-47d: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 140000 "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 1.6 1.9 15.1 1.2 15.0 1.0 13.4 18.6 14.1 7.8 1.1 7.6 8.8 1.1 1.5 1.2 1.3 24.5 1.2 7.0 14.3 6.5 11.9 1.1 2.9 1.2 7.8 10.7 1.3 2.4 10.8 5.1 1.3 8.8 1.7 1.1 2.0 9.7 18.1 3.8 1.8 1.2 1.1 7.3 1.2 1.5 7.6 12.0 0.0 4.5 1.1 1.2 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.6 0.2 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.0 0.0 0.0 7.2 1.0 0.0 0.4 0.2 0.0 0.0 0.1 5.3 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.8 0.0 0.0 0.5 0.0 7.8 0.4 4.4 0.2 0.0 0.1 0.1 0.1 7.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 18.6 14.1 14.3 6.5 7.8 10.7 8.8 12.0 0.0 9.3 0.0 0.8 0.6 11.2 15.3 0.0 26.8 17.0 12.2 0.0 0.0 5.0 0.4 4.1 0.1 0.0 0.0 0.4 0.1 0.2 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 1.7 0.0 3.3 0.0 0.0 12.4 0.0 0.0 0.4 0.0 1.4 6.5 3.1 1.9 1.5 1.1 0.0 0.0 0.0 1.0 ERN1 "IRE1, IRE1P" ENSG00000178607 "Endoplasmic reticulum to nucleus signaling 1" O75460 17 64039142-64130819 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Unfolded protein response" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Intestinal endocrine cells: 76.4;Melanocytes: 70.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.9;MAIT T-cell: 12.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 41.3;RPMI-8226: 18.5;U-266/70: 39.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB009495, HPA027730" Supported NA Yes "CAB009495: AB_2098712, HPA027730: AB_10602494" "unprognostic (2.52e-1)" "unprognostic (1.16e-2)" "unprognostic (1.89e-1)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (2.81e-2)" "unprognostic (9.14e-2)" "unprognostic (2.72e-2)" "unprognostic (4.55e-1)" "unprognostic (6.17e-2)" "unprognostic (2.95e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.65e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (3.11e-2)" 5.5 24.9 2.2 10.6 1.6 8.0 7.7 2.3 1.8 15.8 10.0 3.5 36.1 5.1 11.9 15.0 7.4 7.9 10.6 4.1 1.9 1.7 6.4 21.5 12.3 12.6 2.1 1.6 14.7 44.1 2.9 32.8 10.1 1.8 6.6 3.9 5.0 23.2 34.9 4.2 6.6 11.5 4.1 2.2 9.9 8.8 2.8 1.6 11.6 7.5 5.9 16.7 10.0 7.7 0.1 5.7 12.9 0.7 3.0 12.2 1.0 2.2 1.8 0.9 2.4 2.2 1.8 4.5 1.9 4.3 1.3 1.2 1.2 1.2 2.9 1.3 1.4 2.1 1.5 1.2 1.9 3.3 0.8 1.1 2.6 0.9 1.8 13.9 1.2 0.9 2.1 5.3 3.7 11.8 1.9 2.5 2.8 1.8 41.3 1.2 1.5 1.8 0.5 0.4 2.1 1.6 2.0 2.0 18.5 1.1 3.0 3.2 2.0 1.8 3.1 4.5 1.8 1.7 2.7 2.4 1.1 2.7 2.6 1.2 39.0 10.2 2.2 2.1 1.4 1.9 12.9 0.7 0.2 4.6 0.4 12.2 0.1 3.0 3.2 0.3 0.1 0.7 1.3 3.3 3.0 0.2 5.7 0.7 1.0 2.2 1.6 2.3 1.8 1.9 1.7 2.1 1.6 1.8 1.6 0.0 42.2 9.0 42.2 19.6 3.2 5.6 15.3 6.7 7.9 12.2 5.9 6.5 1.7 9.4 1.8 10.8 7.1 0.0 24.0 6.6 16.0 38.4 8.1 21.3 7.7 3.2 76.4 14.1 12.1 1.1 4.4 18.6 70.9 8.2 7.8 4.0 16.0 7.6 5.6 3.7 26.0 0.0 15.1 3.9 4.1 39.4 45.9 42.7 7.6 52.1 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690326-23713500 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 64.5;stomach 1: 30.0" "Cell type enhanced" "Detected in some" 20 "Cholangiocytes: 28.1;Enterocytes: 26.1;Mucus-secreting cells: 126.1;Paneth cells: 28.8;Undifferentiated cells: 53.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "basophil: 3.6" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "OE19: 30.5" "Region enhanced" "Detected in single" "hypothalamus: 0.7" "Not detected" "Not detected" HPA076875 Approved "Intracellular and membrane" NA NA "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.3 0.1 8.1 0.2 0.0 0.1 0.1 0.2 11.4 17.3 0.2 0.1 7.0 1.1 0.1 0.9 0.1 64.5 0.1 0.1 0.0 0.2 0.1 1.0 0.5 0.1 0.1 0.1 0.5 0.0 0.8 0.1 0.1 2.6 12.6 0.2 14.0 0.1 0.1 0.1 11.8 0.9 0.1 0.1 30.0 0.1 0.1 0.2 0.1 2.2 7.6 6.3 3.9 0.9 0.6 3.6 0.4 1.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 30.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.4 0.5 0.3 0.3 0.2 0.3 0.3 0.3 0.1 0.9 0.3 0.4 2.1 1.5 0.2 0.6 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 1.0 0.0 0.0 0.4 28.1 4.0 6.8 0.0 0.0 0.2 0.0 0.6 0.1 0.0 26.1 0.0 1.8 0.0 0.0 1.0 4.6 0.0 0.1 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 126.1 0.0 19.2 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 53.3 10.4 FASTK FAST ENSG00000164896 "Fas activated serine/threonine kinase" Q14296 7 151076593-151080866 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031621, CAB032539" Approved Supported "Nuclear speckles,Mitochondria" NA NA Mitochondria "Nuclear speckles" "CAB032539: AB_2101115, HPA031621: AB_10611966" "unprognostic (7.67e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (4.73e-4)" "unprognostic (2.60e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-3)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (4.66e-2)" "prognostic favorable (3.99e-4)" "unprognostic (3.49e-2)" "unprognostic (2.79e-2)" "unprognostic (4.12e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (8.17e-2)" 13.8 16.8 18.8 15.7 19.0 6.4 10.2 19.0 26.4 18.0 20.6 13.4 20.3 21.2 12.4 14.6 20.3 16.7 16.8 35.7 17.6 12.9 17.7 25.6 9.5 10.4 12.0 15.0 14.4 20.7 20.2 21.8 18.5 12.0 16.8 10.6 14.0 21.7 17.9 89.5 14.4 25.8 11.3 9.2 14.9 14.8 10.6 10.9 11.2 16.8 28.1 16.9 17.4 11.8 15.4 26.0 19.7 22.3 13.1 19.0 14.5 15.9 18.6 5.9 14.2 22.1 10.0 9.9 12.8 17.4 10.9 13.1 12.8 13.7 3.8 17.5 17.3 20.1 10.3 5.7 15.3 2.9 10.9 10.2 4.6 4.6 10.8 28.1 3.2 10.5 13.0 22.5 12.6 9.3 8.9 12.8 9.5 6.8 8.0 12.6 31.9 7.8 9.2 9.9 19.8 21.8 5.2 7.1 11.8 14.8 10.9 7.1 7.4 16.9 26.2 17.0 5.3 14.1 12.7 10.4 13.9 3.0 13.0 11.3 21.4 13.0 2.4 27.7 7.2 15.9 10.5 22.3 19.7 16.4 21.7 17.1 13.7 17.3 16.9 19.4 15.4 19.0 16.3 4.8 13.1 20.8 26.0 18.7 14.5 18.8 19.0 19.0 26.4 17.6 12.9 12.0 15.0 12.0 10.9 0.0 6.5 32.8 35.2 21.9 39.2 16.5 28.1 2.7 12.5 24.4 23.6 42.5 72.9 43.5 7.1 22.2 63.6 0.0 41.8 23.0 34.8 27.1 39.1 31.6 38.4 35.0 43.1 22.7 26.6 11.6 33.6 25.5 89.4 34.3 42.5 51.0 35.5 39.6 32.2 50.2 48.9 12.9 27.8 47.1 68.2 22.1 50.6 38.4 50.8 26.7 FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747822-109196841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 123.9;granulocytes: 91.4;Late spermatids: 142.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 45.1" "Low region specificity" "Detected in all" "HPA007641, CAB022464" Approved Supported Cytosol NA NA Cytosol "CAB022464: , HPA007641: AB_1078845" "unprognostic (1.72e-1)" "unprognostic (1.66e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-3)" "unprognostic (4.72e-2)" "unprognostic (5.65e-2)" "unprognostic (6.81e-2)" "unprognostic (7.39e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-3)" "unprognostic (7.36e-2)" "unprognostic (8.05e-2)" "prognostic favorable (5.55e-4)" "unprognostic (3.83e-3)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-3)" 13.4 5.7 5.5 6.1 13.4 1.8 5.2 6.0 5.0 9.7 6.7 1.4 16.8 2.5 6.5 19.3 8.2 4.6 5.3 4.6 4.8 4.8 7.2 3.6 12.2 1.9 4.9 2.2 7.2 3.0 18.5 15.9 5.7 3.1 6.8 3.6 5.0 4.5 21.9 5.0 6.6 3.5 7.2 6.2 8.1 4.1 15.9 2.6 3.9 10.2 12.8 2.8 7.7 9.0 10.5 5.4 8.0 5.1 1.2 2.8 1.1 4.7 1.6 5.8 9.2 3.5 5.4 3.7 5.7 5.6 3.4 4.0 9.7 2.9 7.6 3.6 6.9 4.3 3.4 3.1 7.2 7.6 3.2 4.2 5.1 7.4 3.5 2.3 2.7 4.3 3.2 4.0 8.1 9.2 3.4 5.0 7.4 6.3 5.7 4.3 1.3 2.1 0.8 0.8 0.4 3.4 1.7 5.6 45.1 3.3 1.6 1.9 2.8 9.4 0.5 6.1 3.8 2.2 1.2 7.3 6.5 5.0 3.3 4.5 4.8 7.2 3.0 4.1 0.9 3.0 8.0 5.1 5.4 1.7 3.1 2.8 10.5 1.0 1.8 2.8 3.8 1.6 2.0 0.4 1.2 2.4 5.4 2.1 1.1 5.5 13.4 6.0 4.2 4.8 4.8 4.9 2.2 3.1 2.6 74.5 27.0 2.4 9.8 26.0 16.3 18.6 12.7 40.2 33.0 14.0 17.7 3.0 1.7 11.7 123.9 13.3 3.2 0.0 5.2 8.9 10.4 8.2 91.4 1.6 6.8 17.5 8.1 22.1 10.5 142.5 17.8 10.6 13.5 12.6 3.7 10.9 7.7 3.6 16.6 5.4 16.6 6.5 9.9 4.3 9.1 15.4 2.6 9.2 3.8 4.9 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 60.8;lymphoid tissue: 49.7" "Cell type enhanced" "Detected in many" 11 "Hofbauer cells: 40.6;Kupffer cells: 93.1;Macrophages: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "eosinophil: 60.8" "Group enriched" "Detected in many" 4 "dendritic cells: 32.6;granulocytes: 60.8;monocytes: 30.5" "Cell line enhanced" "Detected in many" "HEL: 21.3;HL-60: 19.0;HMC-1: 40.7;NB-4: 24.9;THP-1: 37.4;U-937: 16.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 14.9 3.4 4.8 9.7 4.1 38.3 12.7 2.4 5.7 6.8 5.4 3.2 4.7 3.0 7.4 5.6 4.9 7.6 7.3 7.9 4.2 2.2 5.2 11.8 12.7 23.3 3.7 0.9 6.4 3.7 1.8 2.7 8.1 7.2 7.7 2.4 5.3 33.8 6.3 3.4 3.5 5.2 5.4 6.9 49.7 4.3 3.2 4.7 3.1 7.2 4.1 4.5 7.2 9.4 1.1 32.6 60.8 30.5 9.3 0.1 13.8 0.1 0.2 0.3 3.6 1.0 3.1 6.1 0.9 0.0 1.8 1.0 0.9 0.0 2.3 0.1 2.0 0.0 0.5 0.6 0.1 0.5 1.2 0.3 21.3 0.0 3.8 2.1 19.0 40.7 3.1 0.0 2.6 0.0 0.0 10.8 3.2 0.6 0.0 0.0 6.9 0.6 24.9 1.0 0.8 0.0 2.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.9 1.1 0.0 37.4 8.4 0.0 3.7 0.1 0.0 0.0 2.7 0.8 0.1 16.1 0.8 10.4 30.5 60.8 0.1 17.6 0.0 1.1 0.0 0.0 32.6 0.9 0.0 0.0 20.0 9.3 7.3 12.9 0.0 13.8 4.8 4.1 2.4 5.7 4.2 2.2 3.7 0.9 7.2 4.7 3.0 8.0 6.4 4.7 3.4 0.0 2.5 5.1 0.0 0.0 1.8 0.0 4.5 3.3 4.8 1.1 24.5 0.4 0.0 3.9 3.8 6.2 4.0 28.8 8.2 40.6 0.0 2.9 22.7 93.1 4.7 8.3 37.3 6.8 27.1 2.1 2.3 2.0 0.0 9.6 1.3 1.9 12.9 7.2 3.5 9.1 2.5 3.8 10.2 2.6 5.2 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38411138-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease mutation, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Leydig cells: 177.8;Muller glia cells: 106.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 111.2;BJ hTERT+: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 120000000 "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 41.1 8.6 12.5 14.5 12.2 7.2 39.5 45.0 10.5 36.0 31.5 10.1 11.6 5.5 29.3 20.6 22.9 29.4 32.4 31.7 12.8 10.1 11.8 5.4 18.6 9.7 11.4 14.3 42.0 51.2 11.5 22.3 28.4 20.0 28.2 10.8 35.8 14.0 31.6 12.0 12.9 14.4 52.4 15.6 4.5 16.4 16.4 8.5 11.3 12.6 13.0 9.8 39.6 41.2 1.6 0.7 1.8 1.1 0.8 5.7 0.7 2.4 9.4 41.1 111.2 25.5 18.2 27.1 25.3 50.7 17.6 18.4 6.1 1.4 0.3 7.0 24.2 22.6 0.0 19.4 1.2 20.4 6.6 4.3 0.0 1.6 6.0 14.4 5.9 0.1 16.5 0.1 14.3 2.9 9.5 16.9 1.4 2.3 0.1 8.3 2.9 17.4 2.0 28.9 0.3 3.9 16.0 4.3 0.0 8.5 0.0 1.6 3.6 4.5 0.2 1.0 21.5 2.3 1.1 10.6 11.5 6.4 31.8 6.0 0.4 0.8 0.0 13.6 0.3 6.0 1.4 1.1 0.4 5.7 0.3 3.9 0.7 2.7 3.7 0.1 1.6 1.5 4.1 1.8 0.8 0.5 0.7 2.2 0.7 12.5 12.2 45.0 10.5 12.8 10.1 11.4 14.3 20.0 8.5 3.0 12.0 0.0 68.4 27.9 1.3 48.2 17.8 1.4 9.1 8.7 3.9 6.5 0.0 23.4 14.2 57.3 0.0 0.0 56.3 69.1 85.6 80.3 8.1 0.9 19.7 20.6 24.0 47.3 3.2 9.3 177.8 7.5 32.1 2.8 0.0 106.2 29.8 0.0 93.7 8.0 2.4 12.9 68.0 1.4 11.3 17.2 8.7 6.4 0.4 8.4 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478334-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.8" "Cell type enhanced" "Detected in many" 16 "Cholangiocytes: 191.1;Club cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 10.8;eosinophil: 4.6" "Lineage enriched" "Detected in single" 35 "granulocytes: 10.8" "Cell line enhanced" "Detected in some" "AN3-CA: 58.9;BEWO: 19.8;CACO-2: 15.4;HaCaT: 17.8;HAP1: 19.1;NTERA-2: 18.9;T-47d: 15.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 500000 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 2.1 8.8 16.4 3.0 30.3 0.0 9.9 15.8 21.3 6.8 14.1 55.7 5.6 4.2 22.0 6.6 10.2 12.5 12.5 1.4 20.6 11.1 11.4 16.1 13.1 1.0 41.2 13.3 7.4 12.8 25.5 2.5 6.2 30.2 11.7 8.7 16.4 23.8 24.3 0.4 45.4 4.7 18.3 74.8 0.5 9.3 2.9 32.1 0.8 23.4 1.6 3.4 6.9 8.5 0.1 0.1 10.8 0.1 0.1 0.3 0.0 2.2 0.1 9.2 58.9 0.0 0.0 19.8 0.1 0.0 0.0 0.0 15.4 0.3 0.0 4.2 0.9 0.0 17.8 19.1 4.0 0.0 0.0 4.1 0.0 0.0 0.3 0.4 0.0 3.8 0.0 8.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 18.9 2.7 0.0 0.0 0.0 2.3 5.7 5.0 0.1 0.1 0.1 10.8 0.0 11.5 15.8 0.0 0.0 0.1 2.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 10.8 0.1 4.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 16.4 30.3 15.8 21.3 20.6 11.1 41.2 13.3 30.2 32.1 17.9 31.8 0.0 29.5 35.6 0.0 2.7 191.1 18.7 52.4 34.9 0.0 12.6 0.0 4.0 2.9 0.5 2.6 0.0 0.2 2.7 17.5 9.8 0.0 4.3 2.0 0.0 2.4 3.1 0.3 6.5 1.1 1.3 5.0 1.0 32.0 1.6 0.6 1.4 5.6 11.5 0.1 0.0 2.1 0.9 7.7 24.2 3.3 1.5 3.0 27.7 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease mutation, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 131.7" "Cell type enhanced" "Detected in many" 9 "Basal keratinocytes: 92.2;Cholangiocytes: 94.3;Suprabasal keratinocytes: 77.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 19.3;HaCaT: 15.1;Hep G2: 32.5;NTERA-2: 15.8;RT4: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 670000 "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.5 1.5 24.7 1.7 30.3 1.6 4.2 10.2 22.0 4.1 4.9 15.8 3.4 9.9 1.8 2.7 26.9 2.0 5.0 2.0 21.6 11.7 9.6 7.4 4.5 1.3 17.6 21.5 1.1 23.0 1.2 3.0 5.6 15.1 3.7 3.8 1.7 3.8 9.0 1.7 131.7 7.4 1.3 9.0 2.1 4.9 8.1 10.6 0.1 1.3 8.5 7.3 8.5 10.1 0.1 0.6 0.1 0.1 0.2 0.3 0.0 0.0 1.5 9.2 2.6 0.0 0.1 9.4 1.1 0.1 0.4 0.2 19.3 0.4 0.0 7.7 0.3 0.4 15.1 2.6 0.1 0.1 0.1 9.7 6.0 1.5 32.5 0.0 0.0 0.2 0.0 5.1 0.1 0.0 0.0 0.0 0.9 6.5 0.0 0.0 9.6 0.4 0.2 15.8 8.8 0.0 0.5 0.5 0.1 1.3 19.3 2.7 0.7 0.8 1.6 0.0 11.1 9.0 1.1 0.4 0.0 0.9 0.2 0.6 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.6 0.1 0.0 24.7 30.3 10.2 22.0 21.6 11.7 17.6 21.5 15.1 10.6 0.0 23.8 2.4 3.6 92.2 0.0 2.0 94.3 0.0 21.6 14.0 0.0 0.4 0.0 4.8 5.4 0.9 20.6 0.0 0.6 9.2 7.0 3.3 0.0 27.0 0.5 0.0 4.1 14.7 1.2 0.4 0.6 1.2 11.8 1.0 20.7 0.2 0.4 17.3 0.4 7.5 0.6 0.0 2.8 0.4 17.9 77.5 0.7 0.0 13.0 11.8 FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086886-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 33.6;kidney: 37.7;liver: 45.3" "Cell type enhanced" "Detected in many" 11 "Cholangiocytes: 50.9;Hepatocytes: 23.7;Proximal tubular cells: 19.5;Sertoli cells: 19.4;Undifferentiated cells: 33.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "neutrophil: 3.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "CACO-2: 43.0;Hep G2: 43.0;RH-30: 69.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" NA NA 4300000 "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" 0.5 5.7 0.7 14.3 0.6 0.1 1.6 2.6 0.5 2.8 10.4 0.9 0.7 13.5 0.9 4.8 1.6 1.7 33.6 0.7 0.8 0.3 37.7 45.3 25.3 2.5 0.7 1.0 13.6 26.0 0.0 0.7 1.3 0.8 4.0 3.7 2.0 1.6 0.3 4.3 0.5 17.3 1.6 0.8 11.2 5.4 2.9 0.4 0.3 0.8 2.3 0.7 1.9 3.6 1.1 0.9 3.0 1.1 0.4 0.4 0.0 0.7 12.1 0.2 2.9 0.0 0.0 5.9 0.0 0.0 0.0 0.0 43.0 1.6 1.3 5.6 0.0 0.6 0.6 2.4 0.4 0.0 0.7 2.8 0.1 0.6 43.0 1.3 0.1 1.0 0.2 0.0 2.1 0.0 0.0 0.0 0.8 4.0 0.1 0.9 9.8 0.0 0.8 7.3 7.6 1.0 1.9 69.1 7.2 5.8 0.1 0.4 0.7 0.4 3.1 1.4 1.6 2.9 0.6 0.2 0.0 5.8 0.0 0.1 0.4 0.4 0.7 0.0 0.2 0.5 1.5 1.1 0.4 0.4 0.3 0.3 1.1 0.4 0.0 0.1 0.6 0.4 0.4 3.0 0.4 0.3 0.9 0.2 0.0 0.7 0.6 2.6 0.5 0.8 0.3 0.7 1.0 0.8 0.4 0.0 0.0 0.8 0.6 0.6 0.4 0.8 50.9 0.0 0.0 3.5 0.0 1.1 3.3 8.4 0.1 0.1 10.6 0.0 4.4 3.2 1.7 0.3 0.0 23.7 0.3 0.0 4.1 2.5 0.8 0.0 0.6 0.0 0.0 1.0 5.2 0.9 3.6 2.9 1.4 19.5 0.1 19.4 0.5 1.6 12.8 0.4 7.3 0.0 33.6 0.6 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635277 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 20.8;blood: 68.0;bone marrow: 73.6;lung: 30.9;lymphoid tissue: 54.3" "Cell type enhanced" "Detected in many" 19 "Hofbauer cells: 58.9;Kupffer cells: 187.9;Macrophages: 86.1;T-cells: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Daudi: 30.1;U-266/70: 55.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" NA NA "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 20.8 2.6 2.2 23.6 4.5 73.6 5.6 1.1 4.2 2.9 2.8 1.5 4.2 1.6 4.0 2.3 2.2 6.3 5.3 8.5 2.6 2.3 3.0 4.2 30.9 34.1 6.6 1.7 1.9 2.4 0.4 1.2 3.3 4.2 2.5 1.8 2.1 2.9 2.6 4.4 1.7 3.7 6.4 4.8 54.3 2.5 2.6 4.1 1.9 2.9 2.5 7.8 5.1 6.1 13.3 28.9 40.8 68.0 36.3 29.6 55.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 10.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 55.9 0.7 2.3 0.0 6.8 0.0 3.1 52.4 32.3 29.6 68.0 1.7 7.7 2.6 13.6 28.9 13.3 1.3 12.8 40.8 36.3 55.6 1.3 0.1 55.0 2.2 4.5 1.1 4.2 2.6 2.3 6.6 1.7 4.2 4.1 6.0 30.7 12.5 0.5 2.5 0.0 1.6 2.5 2.7 10.3 1.8 0.0 0.4 0.0 0.0 0.2 11.5 0.0 0.0 0.2 0.5 1.4 0.3 12.7 0.9 58.9 0.0 0.0 4.3 187.9 0.4 0.3 86.1 1.7 7.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.2 0.5 1.0 0.8 45.8 0.0 0.9 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related tyrosine kinase 1" P17948 13 28300344-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "placenta: 155.3" "Cell type enhanced" "Detected in many" 16 "Extravillous trophoblasts: 778.4;Ito cells: 284.2;Syncytiotrophoblasts: 942.6" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 1.1;naive B-cell: 3.7;neutrophil: 2.1" "Group enriched" "Detected in many" 5 "B-cells: 3.7;granulocytes: 2.1" "Cell line enhanced" "Detected in some" "BJ: 17.4;BJ hTERT+: 13.8;HMC-1: 86.4;HUVEC TERT2: 15.6;WM-115: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 54000 "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 18.9 4.0 9.9 4.0 14.3 1.2 13.5 8.0 15.9 7.1 4.6 3.5 1.7 3.5 7.2 2.2 3.4 4.0 6.9 18.3 11.4 7.3 10.3 7.6 12.3 2.5 10.3 3.2 5.1 5.4 13.4 3.7 155.3 13.8 5.1 3.1 9.1 3.0 5.0 12.5 2.6 3.4 7.3 9.6 7.2 4.6 6.8 10.2 0.0 19.1 3.8 2.8 7.6 9.2 3.7 0.5 2.1 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 17.4 13.8 6.3 3.7 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.6 0.0 11.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 86.4 0.1 0.0 0.0 0.2 0.0 15.6 1.4 0.4 0.0 0.0 0.0 1.0 0.8 9.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 11.4 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.5 0.2 0.0 0.1 0.0 31.0 0.2 0.1 0.1 0.1 0.1 0.0 1.1 0.1 0.1 0.0 3.7 0.4 0.4 2.1 0.2 0.1 0.5 0.2 0.2 9.9 14.3 8.0 15.9 11.4 7.3 10.3 3.2 13.8 10.2 0.0 8.9 2.2 0.5 3.7 5.9 12.6 5.1 2.7 1.2 0.0 3.9 155.4 1.7 0.0 116.6 192.1 0.0 0.0 0.0 778.4 17.5 1.1 1.1 2.1 28.1 1.6 0.0 284.2 16.1 130.7 17.3 5.3 0.0 0.0 0.0 172.0 0.0 0.0 45.6 0.0 7.3 90.5 6.6 12.9 2.8 4.3 942.6 2.9 0.0 0.5 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.9;brain: 19.3;lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" 25 "Kupffer cells: 29.6;Macrophages: 12.4;monocytes: 55.9" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in many" "cerebellum: 19.3" "Group enriched" "Detected in some" 11 "myeloid DC: 29.9;plasmacytoid DC: 12.1" "Lineage enriched" "Detected in many" 16 "dendritic cells: 29.9" "Group enriched" "Detected in some" 11 "REH: 28.5;THP-1: 17.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 180000 "Endoplasmic reticulum" "HPA047539: AB_2680080" "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.9 0.6 0.6 7.2 1.1 7.5 2.6 19.3 3.5 0.9 1.2 0.1 0.1 0.4 0.8 0.8 1.0 1.2 4.6 0.5 0.9 1.7 2.8 0.7 2.7 15.0 1.8 1.1 0.5 5.7 0.0 0.4 0.0 7.4 0.6 1.4 0.1 2.3 0.6 0.4 1.2 3.0 1.3 4.4 8.8 0.9 1.2 0.0 8.2 0.6 0.0 5.8 2.4 0.7 0.1 29.9 1.4 1.8 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.1 0.5 0.0 0.0 28.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.8 1.4 0.0 0.3 0.0 0.1 0.0 0.0 29.9 0.0 0.0 0.0 0.0 0.8 0.0 12.1 0.0 1.2 0.6 1.1 19.3 3.5 0.9 1.7 1.8 1.1 7.4 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 1.3 29.6 1.6 0.0 12.4 1.7 55.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.5 0.0 0.0 0.0 0.0 FLT4 "PCL, VEGFR3" ENSG00000037280 "Fms related tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 56.3" "Group enriched" "Detected in some" 5 "Extravillous trophoblasts: 31.7;Ito cells: 65.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "MAIT T-cell: 7.7" "Lineage enriched" "Detected in single" 35 "T-cells: 7.7" "Cell line enhanced" "Detected in some" "AN3-CA: 8.3;BEWO: 10.1;HEK 293: 12.5;HUVEC TERT2: 8.1;JURKAT: 10.0;T-47d: 11.9;TIME: 12.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 270000000 "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 14.8 7.1 1.6 4.9 6.0 0.7 28.5 1.3 2.7 6.3 7.3 1.9 2.1 3.1 7.3 6.2 5.7 9.2 5.3 6.4 1.7 0.9 11.7 10.2 14.1 23.6 2.0 0.8 5.8 2.3 2.3 6.2 56.3 2.1 4.9 1.4 6.7 3.3 4.4 4.8 2.8 4.7 4.7 1.5 14.5 2.4 3.5 2.0 0.3 19.4 4.4 2.3 6.1 14.7 0.0 0.1 0.2 0.0 0.0 7.7 0.2 0.1 2.0 2.7 8.3 0.0 0.0 10.1 0.2 0.1 0.0 0.0 0.3 0.3 0.2 0.8 0.1 0.5 0.3 2.8 0.1 0.2 0.1 12.5 1.0 0.4 0.4 0.1 7.4 0.2 0.2 0.0 0.1 0.3 0.3 8.1 10.0 0.3 0.3 1.7 4.5 0.1 0.4 5.8 0.2 0.5 6.5 0.0 0.1 0.1 0.2 0.2 0.9 0.1 0.2 0.0 2.7 11.9 0.2 12.6 0.1 5.9 0.2 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.9 0.0 7.7 0.0 0.4 1.6 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 1.6 6.0 1.3 2.7 1.7 0.9 2.0 0.8 2.1 2.0 0.0 1.7 0.9 0.2 0.8 0.0 4.5 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.2 9.2 0.0 0.0 0.0 31.7 0.6 0.2 2.3 0.4 1.1 0.0 0.0 65.1 5.7 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 4.3 1.0 0.8 0.7 0.0 0.1 FRK "GTK, PTK5, RAK" ENSG00000111816 "Fyn related Src family tyrosine kinase" P42685 6 115931149-116060758 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.4" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 73.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 19.0;RT4: 8.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB025217, HPA030479, HPA072590" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB025217: , HPA030479: AB_2732457, HPA072590: " "unprognostic (7.70e-3)" "unprognostic (1.99e-2)" "unprognostic (1.11e-1)" "unprognostic (4.68e-3)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (4.23e-2)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (7.54e-2)" "prognostic favorable (9.66e-7)" "unprognostic (1.52e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.10e-1)" 1.5 2.2 0.8 3.0 1.3 1.3 2.6 0.5 0.8 6.4 21.4 0.2 10.2 6.8 1.6 9.0 10.5 2.8 7.3 3.3 1.2 0.8 23.7 19.6 5.6 0.6 1.5 0.5 2.4 5.9 0.3 3.8 2.7 0.8 4.1 5.5 0.8 9.2 6.1 2.9 2.0 41.4 2.5 2.4 1.0 5.5 1.8 0.5 1.2 1.0 5.2 7.4 5.0 3.6 2.2 1.2 3.8 1.2 1.4 2.3 0.3 2.5 4.2 0.7 1.0 0.3 0.3 0.8 0.6 0.2 0.0 0.1 3.3 4.1 1.1 3.9 0.6 0.6 6.1 0.3 1.2 0.1 3.5 0.4 1.4 3.6 2.8 0.2 1.0 0.9 0.3 1.7 0.4 0.4 0.5 0.2 0.7 0.7 2.6 1.0 1.4 0.8 0.6 1.1 19.0 0.7 1.2 3.7 1.3 5.2 8.0 0.9 1.0 0.9 5.4 0.5 1.1 1.6 0.8 1.0 1.2 1.2 0.9 0.6 4.0 2.8 1.8 1.2 0.7 0.8 3.2 1.0 1.0 1.9 0.6 2.3 1.1 1.4 1.7 0.4 2.2 1.1 1.4 3.8 1.4 1.2 1.2 1.0 0.3 0.8 1.3 0.5 0.7 1.2 0.8 1.5 0.5 0.8 0.5 0.0 10.1 0.0 15.3 2.4 0.7 8.4 12.7 22.7 15.9 22.7 0.0 4.3 10.0 16.5 73.1 0.3 35.5 0.0 14.3 3.8 3.5 20.3 3.5 19.2 0.8 6.4 19.0 1.8 0.6 17.7 0.6 0.5 0.0 1.8 13.0 0.3 19.1 20.1 1.1 22.5 0.0 12.9 7.5 1.4 0.7 2.8 0.7 0.5 16.1 34.6 FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Proximal tubular cells: 145.7;T-cells: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "NK-cells: 15.3;T-cells: 43.2" "Cell line enhanced" "Detected in many" "U-2197: 105.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Enhanced "Plasma membrane,Cytosol" NA NA 2000000 "Plasma membrane" Cytosol "CAB005034: AB_562117, CAB018387: AB_627642, HPA023887: AB_1849226, HPA063770: AB_2685119" "unprognostic (8.62e-3)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "prognostic favorable (1.84e-4)" "unprognostic (4.60e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "prognostic favorable (4.78e-4)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-4)" "unprognostic (6.95e-2)" "unprognostic (3.10e-1)" "unprognostic (6.62e-3)" "unprognostic (2.40e-1)" 29.1 7.2 49.2 29.0 38.4 16.3 18.1 33.9 62.1 25.7 12.1 33.7 4.1 10.1 21.8 21.4 10.2 32.0 19.4 21.2 39.4 34.0 9.5 12.2 25.2 57.2 35.7 23.1 18.6 4.4 15.0 12.5 17.7 25.6 9.6 10.0 11.0 6.4 8.4 7.0 16.5 19.0 24.2 30.9 39.8 15.4 10.1 31.3 34.8 27.5 5.6 38.5 22.6 19.3 1.6 1.7 0.7 1.5 15.3 43.2 10.7 1.9 0.3 34.9 5.8 26.7 16.4 0.6 5.5 17.5 4.7 8.5 0.2 0.3 3.9 3.6 10.7 4.1 0.2 4.9 7.6 9.2 0.1 12.8 10.7 2.6 0.5 15.8 3.6 3.7 15.8 11.6 17.7 15.2 12.4 19.2 19.2 0.9 27.3 16.8 0.2 17.1 3.3 5.0 0.6 3.5 5.4 4.7 0.2 0.0 1.7 24.5 9.9 1.0 0.4 23.3 8.1 0.2 10.8 12.2 14.3 2.6 105.3 3.5 3.9 3.5 6.0 26.9 8.4 24.8 0.2 1.5 0.0 34.1 1.2 43.2 1.1 21.2 37.5 1.7 1.6 7.0 18.7 0.7 15.3 0.9 1.0 17.6 10.7 49.2 38.4 33.9 35.3 39.4 34.0 35.7 23.1 25.6 31.3 0.0 11.7 18.8 1.9 15.1 53.9 9.2 12.7 5.3 3.4 7.0 0.0 2.2 14.9 8.1 2.8 56.2 3.5 0.0 0.9 2.1 36.8 1.4 51.8 59.3 2.8 44.5 12.7 71.8 42.5 0.9 24.5 33.6 35.4 3.6 2.4 88.8 6.3 0.0 6.7 145.7 7.8 12.9 23.1 2.6 4.3 11.7 43.5 208.1 1.2 0.9 GAK DNAJC26 ENSG00000178950 "Cyclin G associated kinase" O14976 4 849276-932373 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027405, HPA027459, HPA027463" Approved Supported "Golgi apparatus,Vesicles" NA NA "Golgi apparatus" Vesicles "HPA027405: AB_10611111, HPA027459: AB_10599948, HPA027463: AB_10601959" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.24e-3)" "unprognostic (1.07e-1)" "unprognostic (3.50e-3)" "unprognostic (1.68e-1)" "unprognostic (7.07e-2)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.70e-6)" "unprognostic (1.09e-3)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "prognostic favorable (7.41e-4)" 16.5 18.9 16.8 42.2 22.7 29.9 16.7 32.4 27.7 18.0 32.5 19.7 18.6 48.2 22.4 18.6 23.7 20.5 26.8 11.4 16.2 13.9 25.0 22.1 22.2 22.4 17.6 19.4 21.1 33.0 19.5 18.9 16.6 17.9 20.3 15.2 16.9 70.8 20.6 26.2 25.6 41.1 15.2 14.3 30.9 39.2 28.6 18.5 23.6 19.7 19.2 22.3 18.9 18.9 4.7 7.1 10.8 19.3 4.0 8.5 6.9 15.9 12.8 7.8 13.3 7.9 6.8 20.2 15.1 9.1 10.4 8.7 16.2 22.8 13.6 10.3 9.1 18.8 13.9 8.1 12.5 4.9 13.8 14.2 15.7 12.9 12.1 14.8 16.0 24.8 9.8 10.8 10.5 5.1 6.6 11.4 16.2 16.9 17.3 7.0 15.4 27.0 41.3 14.0 17.0 23.5 22.4 9.1 12.1 8.4 13.0 13.5 14.7 8.8 11.2 10.5 6.9 18.0 13.8 18.6 14.5 8.5 14.7 20.1 28.0 18.7 15.1 16.4 19.6 13.3 2.6 9.0 10.8 8.5 8.9 7.4 4.7 5.6 5.7 6.0 4.0 3.2 4.7 6.7 4.0 19.3 7.1 5.0 6.9 16.8 22.7 32.4 27.7 16.2 13.9 17.6 19.4 17.9 18.5 23.8 28.6 15.3 12.6 15.0 27.8 9.5 15.3 16.0 22.7 24.4 60.9 16.1 8.3 16.1 102.1 20.4 83.6 0.0 24.3 13.5 15.3 23.7 17.4 25.9 31.3 11.1 28.3 21.5 37.8 102.9 23.3 25.0 15.1 16.2 53.5 15.6 29.1 45.8 17.7 26.4 25.2 19.4 15.3 30.2 26.3 19.4 26.0 27.3 45.3 36.3 GRK1 "GPRK1, RHOK, RK" ENSG00000185974 "G protein-coupled receptor kinase 1" Q15835 13 113667155-113737735 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Congenital stationary night blindness, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "retina: 51.5" "Group enriched" "Detected in some" 26 "Cone photoreceptor cells: 53.0;Rod photoreceptor cells: 86.9" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035200, HPA059376" Enhanced NA NA "HPA035200: AB_2674515, HPA059376: AB_2683996" "unprognostic (7.93e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (1.24e-5)" "unprognostic (1.76e-3)" "unprognostic (1.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.21e-2)" "unprognostic (1.84e-3)" "unprognostic (2.00e-2)" "unprognostic (4.02e-2)" "unprognostic (6.91e-2)" "unprognostic (6.18e-2)" "unprognostic (6.11e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 51.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 53.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 86.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GRK2 "ADRBK1, BARK1" ENSG00000173020 "G protein-coupled receptor kinase 2" P25098 11 67266410-67286556 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 78.2" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 2: 26.5;granulocytes: 19.8;Hofbauer cells: 31.0;monocytes: 15.4;Pancreatic endocrine cells: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 56.3;REH: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005021, CAB037248, HPA048330" Enhanced Approved Vesicles NA NA Vesicles "CAB005021: AB_562360, CAB037248: AB_1078280, HPA048330: AB_2680361" "unprognostic (5.58e-2)" "unprognostic (1.75e-1)" "unprognostic (2.01e-2)" "unprognostic (5.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-3)" "unprognostic (3.31e-2)" "unprognostic (6.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-2)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (3.66e-1)" "unprognostic (2.40e-1)" "unprognostic (4.04e-2)" "unprognostic (5.19e-3)" 13.1 10.7 24.5 35.8 17.0 78.2 17.0 32.9 35.3 12.8 17.2 12.2 12.6 17.5 11.4 9.9 20.2 12.6 17.6 13.6 21.9 17.4 13.0 14.1 19.1 42.8 13.4 19.0 9.8 10.4 9.7 12.2 12.7 15.7 17.8 16.2 9.3 17.4 20.8 20.8 23.5 26.3 12.2 12.5 59.6 17.4 6.8 11.1 35.9 10.1 13.6 37.5 17.1 15.5 4.1 6.0 21.0 18.3 3.8 5.3 7.4 7.6 5.4 5.3 8.9 4.3 3.9 5.3 4.6 4.4 6.3 5.2 12.0 12.8 39.5 7.4 4.2 8.4 10.4 7.7 6.2 3.3 48.1 4.8 22.4 6.2 5.4 5.3 47.0 45.0 3.5 7.3 5.0 6.7 4.7 8.0 16.2 8.1 20.3 5.4 14.3 26.1 56.3 6.6 23.1 8.2 74.7 10.5 11.7 6.4 10.1 10.7 5.8 6.8 10.0 16.3 3.4 9.2 51.1 4.4 5.0 6.6 6.3 5.1 12.9 11.9 35.4 6.5 27.9 4.5 6.9 10.3 10.5 5.3 15.9 4.0 3.8 4.0 4.3 6.0 4.1 3.2 3.1 21.0 3.8 18.3 5.3 2.6 7.4 24.5 17.0 32.9 35.3 21.9 17.4 13.4 19.0 15.7 11.1 3.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 7.9 5.2 0.0 7.8 1.7 9.4 0.0 0.0 0.0 0.0 10.9 5.1 0.0 0.0 19.8 0.0 31.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 15.4 0.0 0.0 22.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564849-25729294 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.0" "Cell type enhanced" "Detected in many" 10 "Alveolar cells type 2: 44.1;Club cells: 30.7;Extravillous trophoblasts: 22.7;Hofbauer cells: 25.0;monocytes: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.8;eosinophil: 5.6;intermediate monocyte: 8.0;memory B-cell: 4.9;myeloid DC: 3.7;naive B-cell: 6.2;non-classical monocyte: 7.4;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 20.4;JURKAT: 33.6;SH-SY5Y: 18.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 28.0 6.0 11.9 12.4 10.8 7.0 11.3 7.9 18.9 4.7 4.0 3.1 0.7 3.0 5.7 3.1 2.7 9.1 5.0 4.6 15.7 8.3 3.0 3.4 9.4 14.1 9.7 9.8 4.1 8.4 4.4 8.2 4.5 9.6 8.2 4.3 4.8 3.7 1.9 1.4 4.1 6.1 6.2 4.9 23.2 4.0 14.8 2.7 11.6 4.5 1.3 15.2 6.7 2.5 6.2 3.7 5.6 8.0 0.0 0.4 1.6 0.0 1.9 5.8 1.9 4.1 0.5 8.5 0.6 1.8 1.8 3.2 3.0 3.3 10.6 0.1 0.1 5.2 0.1 5.8 4.3 5.5 20.4 3.8 4.9 0.6 6.7 0.1 15.8 8.3 1.0 3.0 1.3 2.3 0.3 0.3 33.6 0.5 0.0 2.1 2.6 11.3 1.1 4.1 5.7 0.0 5.1 9.3 1.8 0.0 3.1 13.7 18.5 1.0 0.0 4.4 5.6 1.6 6.3 0.1 0.0 12.0 0.1 2.3 1.2 4.2 8.3 7.8 5.6 1.8 0.6 4.8 5.6 0.0 8.0 0.3 4.9 0.0 0.3 3.7 6.2 0.1 0.2 0.3 0.0 7.4 3.2 0.4 1.6 11.9 10.8 7.9 18.9 15.7 8.3 9.7 9.8 9.6 2.7 14.9 44.1 0.0 0.0 0.0 0.0 0.0 0.0 12.0 30.7 0.0 0.0 1.5 1.7 7.0 0.0 0.0 0.0 0.0 1.6 22.7 0.0 0.0 17.4 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 47.7 0.0 0.0 3.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 GRK4 "GPRK2L, GPRK4" ENSG00000125388 "G protein-coupled receptor kinase 4" P32298 4 2963608-3040747 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.2" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 115.8;Early spermatids: 282.7;Late spermatids: 377.5;Spermatocytes: 110.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028737, HPA057023" Approved Approved Lysosomes NA NA Lysosomes "HPA028737: AB_2672757, HPA057023: AB_2683313" "unprognostic (1.86e-2)" "unprognostic (2.88e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (3.65e-1)" "unprognostic (1.84e-1)" "unprognostic (1.21e-1)" "unprognostic (2.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.87e-1)" "unprognostic (3.90e-4)" "unprognostic (3.20e-1)" "unprognostic (1.01e-2)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.89e-1)" 3.4 3.6 5.4 1.6 5.1 1.7 4.8 12.5 5.9 3.0 2.1 4.2 1.0 1.5 2.7 3.1 2.4 2.0 3.0 5.6 5.2 4.8 2.8 2.3 2.4 1.6 5.3 5.3 3.4 7.9 3.9 6.2 2.2 5.9 2.4 2.0 3.1 4.0 2.9 5.0 2.9 1.7 2.8 5.4 1.9 2.5 41.2 3.7 1.6 4.1 1.6 1.7 2.5 3.3 1.2 2.5 4.5 2.0 1.6 1.7 1.0 2.5 0.9 3.0 8.7 7.4 7.1 1.9 4.9 2.1 2.8 2.4 2.4 0.8 5.6 2.1 7.7 5.4 0.8 4.0 4.0 2.5 3.8 4.0 6.1 3.5 2.8 4.4 2.4 2.2 4.8 6.3 4.9 2.3 3.1 5.2 6.0 5.7 7.4 6.5 2.8 5.2 5.2 2.4 3.5 6.9 6.6 3.9 2.2 2.6 3.1 17.6 5.4 2.9 1.3 4.4 2.2 6.7 3.8 6.0 7.6 2.0 5.1 4.3 7.6 4.3 4.3 3.7 5.4 2.5 4.5 1.1 2.1 1.1 2.0 1.4 1.1 0.7 0.7 0.3 1.2 1.7 1.6 4.0 1.6 0.7 2.5 0.4 1.0 5.4 5.1 12.5 5.9 5.2 4.8 5.3 5.3 5.9 3.7 3.0 9.0 0.0 2.5 10.0 48.5 9.0 7.6 1.4 7.9 3.5 115.8 1.8 11.6 2.4 282.7 3.8 1.0 0.0 3.3 3.5 9.9 1.5 5.7 2.5 3.0 17.5 9.9 3.1 2.2 377.5 12.0 3.2 6.8 2.8 1.7 10.3 1.8 0.0 7.8 3.6 48.9 6.5 4.4 110.9 13.6 9.9 2.5 4.4 1.2 2.3 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207589-119459742 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 53.6;Sertoli cells: 58.2;Smooth muscle cells: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 35.6;HUVEC TERT2: 28.2;OE19: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: AB_2679833" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 15.9 8.3 3.4 16.8 7.8 2.7 10.2 6.5 5.0 12.5 18.8 3.9 4.5 12.4 13.4 12.2 8.1 7.7 19.5 45.4 4.2 4.2 4.3 5.7 27.6 8.8 3.7 2.5 16.5 3.5 26.2 6.3 24.0 4.5 7.5 6.4 5.6 5.0 6.7 12.8 4.7 10.4 10.8 4.8 17.0 13.9 3.5 4.7 9.8 8.9 10.7 8.6 9.5 13.6 9.3 2.2 6.5 3.7 0.2 11.3 4.2 3.9 2.3 5.9 6.0 13.5 13.0 1.7 7.6 35.6 4.7 2.7 1.9 5.7 4.2 1.8 11.9 8.3 0.9 2.5 8.4 3.1 16.7 2.1 0.7 4.9 7.5 9.3 0.2 2.1 1.8 1.2 9.6 1.4 5.7 28.2 2.6 0.4 4.1 1.7 0.6 3.9 3.8 0.8 27.1 5.9 1.4 0.8 1.0 0.7 1.6 1.9 5.4 2.6 1.2 7.3 3.6 0.1 1.0 8.5 2.6 1.8 15.5 3.0 0.9 4.5 2.6 5.4 4.7 2.4 0.9 3.7 6.5 5.3 3.2 0.4 9.3 7.7 3.8 2.2 9.1 11.3 5.0 5.0 0.2 0.9 0.0 9.2 4.2 3.4 7.8 6.5 5.0 4.2 4.2 3.7 2.5 4.5 4.7 53.6 5.9 13.7 0.5 1.4 3.4 14.6 0.0 1.4 2.3 3.5 0.0 2.4 0.0 1.0 11.8 24.8 0.9 0.0 2.7 13.7 12.4 0.6 4.6 1.7 3.6 1.6 4.6 21.5 10.4 2.9 4.0 5.1 6.8 0.0 0.7 0.0 1.7 0.2 4.2 0.4 0.7 58.2 37.3 1.4 1.7 2.0 11.0 10.2 0.3 0.9 GRK6 GPRK6 ENSG00000198055 "G protein-coupled receptor kinase 6" P43250 5 177403204-177442901 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 68.1" "Cell type enhanced" "Detected in many" 4 "Late spermatids: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015327, HPA018903" Approved Approved Mitochondria NA NA 7500 Mitochondria "HPA015327: AB_1850334, HPA018903: AB_1850335" "unprognostic (1.06e-1)" "unprognostic (3.39e-2)" "unprognostic (4.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.66e-6)" "unprognostic (2.63e-1)" "unprognostic (6.45e-2)" "unprognostic (8.96e-2)" "prognostic favorable (1.22e-4)" "unprognostic (1.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.83e-3)" "unprognostic (1.15e-1)" "unprognostic (4.00e-2)" "unprognostic (3.47e-1)" 6.8 5.5 7.8 26.8 7.3 68.1 10.2 7.7 10.9 5.9 9.2 6.6 5.0 10.9 8.0 6.0 11.0 6.6 9.3 6.2 8.0 7.3 5.7 6.6 11.1 37.6 7.1 10.7 6.1 12.1 3.5 5.6 4.9 6.7 8.1 5.5 5.0 10.8 5.2 7.4 7.7 14.5 7.8 5.4 34.3 9.1 10.5 5.1 32.3 5.3 6.4 26.5 11.4 6.5 9.2 5.7 32.1 22.6 17.4 11.7 9.1 12.1 13.3 4.8 21.1 1.4 2.4 20.7 8.9 4.7 11.3 11.2 30.8 10.4 14.5 13.7 4.7 16.7 8.9 7.5 20.5 4.4 39.6 23.4 12.8 10.8 10.4 7.9 17.2 16.3 3.8 5.1 11.2 6.6 2.8 6.3 26.7 13.3 52.3 3.4 34.8 17.7 18.1 8.3 6.1 14.7 17.0 7.8 20.9 3.3 9.9 11.2 15.2 7.4 13.1 17.3 2.3 10.4 19.0 8.0 9.2 13.8 9.8 22.4 15.1 18.3 11.8 6.2 28.2 8.9 4.5 9.5 32.1 11.7 16.5 8.4 9.2 9.8 10.7 5.5 9.2 10.4 9.0 23.2 17.4 22.6 5.7 11.7 9.1 7.8 7.3 7.7 10.9 8.0 7.3 7.1 10.7 6.7 5.1 0.0 2.1 37.2 46.6 21.1 9.5 2.0 7.6 0.0 3.4 3.5 5.9 10.9 13.3 3.9 31.4 4.5 11.3 23.3 7.1 10.5 8.0 37.0 14.9 5.3 18.5 15.9 10.9 8.6 27.3 57.4 5.8 20.0 13.5 1.8 13.4 6.1 8.1 13.3 4.9 6.9 7.3 12.9 10.3 2.2 3.6 17.8 10.6 41.1 16.3 52.8 GRK7 GPRK7 ENSG00000114124 "G protein-coupled receptor kinase 7" Q8WTQ7 3 141778148-141818490 "Enzymes, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood: 2.4" "Cell type enriched" "Detected in some" 168 "Cone photoreceptor cells: 310.2" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "neutrophil: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 4.1;HeLa: 1.5;U-937: 1.8" "Not detected" "Not detected" "HPA075093, HPA078232" Enhanced Approved Mitochondria NA NA Mitochondria "HPA075093: , HPA078232: " "unprognostic (1.11e-1)" "unprognostic (1.70e-2)" "unprognostic (3.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.39e-2)" "unprognostic (5.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.53e-8)" "unprognostic (3.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (2.91e-1)" 0.2 0.5 0.3 0.5 0.4 1.5 0.2 0.9 0.3 0.2 0.1 0.4 0.3 0.0 0.3 0.3 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.2 0.2 0.6 0.3 0.7 0.2 0.2 0.3 0.0 0.4 0.2 1.6 1.5 0.4 0.0 0.2 0.4 0.1 1.0 0.1 0.3 0.1 0.3 0.7 0.2 2.4 0.4 0.5 0.6 0.1 0.0 0.1 0.1 0.6 0.4 0.0 4.1 0.1 0.0 0.0 0.1 0.2 0.6 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.5 0.5 0.2 1.5 0.2 0.0 0.4 0.3 0.1 1.1 0.0 0.1 0.0 0.0 0.3 0.2 0.2 0.0 0.2 0.2 0.7 0.4 0.2 0.2 0.2 0.1 0.2 0.0 0.5 0.3 0.4 0.2 0.0 0.0 0.2 0.5 0.2 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.2 0.1 1.8 0.2 0.2 0.4 0.3 0.4 0.2 0.6 0.6 0.5 0.3 0.1 0.7 0.5 0.5 2.4 0.5 0.3 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.2 0.0 0.0 0.0 0.0 310.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 GSK3A ENSG00000105723 "Glycogen synthase kinase 3 alpha" P49840 19 42230186-42242625 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004422, HPA028423" Approved Approved Cytosol NA NA Cytosol "CAB004422: AB_627680, HPA028423: AB_10612116" "unprognostic (5.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.02e-4)" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (3.80e-3)" "unprognostic (2.27e-1)" "unprognostic (2.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.36e-1)" "unprognostic (2.69e-1)" "unprognostic (2.77e-2)" "unprognostic (4.49e-2)" "unprognostic (7.22e-2)" "unprognostic (8.22e-3)" 15.3 19.8 31.0 16.8 38.0 14.4 12.0 31.4 62.2 15.9 16.8 24.3 11.4 28.6 16.9 18.0 17.3 16.7 11.8 21.3 31.3 23.6 17.5 13.1 14.2 15.0 21.8 26.3 20.0 19.3 16.1 14.2 14.7 31.7 15.8 16.1 15.5 18.1 20.3 41.0 25.1 27.0 18.5 18.0 14.5 14.7 19.1 17.7 16.6 15.8 11.9 15.8 15.8 15.5 1.6 2.2 4.0 1.9 1.7 2.0 1.0 23.4 41.6 23.8 22.1 14.3 12.8 10.1 16.5 15.8 21.9 19.8 15.6 14.9 17.0 17.1 12.9 20.6 10.8 19.6 19.2 15.4 13.7 31.4 17.7 13.3 15.4 18.8 20.0 21.6 12.5 20.4 17.9 20.5 19.0 19.8 12.7 29.6 25.3 18.7 28.4 25.9 17.7 17.6 36.7 17.2 23.7 13.8 13.0 20.2 24.6 27.8 28.1 22.6 29.7 15.0 17.1 17.2 26.5 17.6 22.6 17.0 13.1 29.2 25.9 29.7 13.2 26.2 20.2 24.7 2.5 1.5 1.6 2.0 1.9 1.4 1.2 1.2 1.3 1.4 1.6 0.7 1.5 4.0 1.7 1.1 2.2 1.0 1.0 31.0 38.0 31.4 62.2 31.3 23.6 21.8 26.3 31.7 17.7 6.0 21.0 14.9 15.9 21.9 42.9 10.9 10.2 1.4 6.8 15.7 58.9 20.8 3.3 12.4 6.3 20.2 39.2 0.0 14.9 21.1 14.6 22.2 2.3 12.4 17.7 57.2 22.4 16.5 18.9 8.8 16.4 16.9 15.1 6.4 28.2 37.9 18.9 22.9 15.6 13.1 40.2 6.5 16.5 10.2 16.6 24.6 36.8 12.8 23.8 23.5 GSK3B ENSG00000082701 "Glycogen synthase kinase 3 beta" P49841 3 119821323-120094417 "Enzymes, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Differentiation, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Horizontal cells: 135.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016263, HPA028017" Approved Supported Nucleoplasm No No 81000 Nucleoplasm "CAB016263: AB_2279451, HPA028017: AB_10600708" "unprognostic (1.09e-2)" "unprognostic (2.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-3)" "unprognostic (1.15e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (3.39e-2)" "unprognostic (1.11e-1)" "unprognostic (1.67e-2)" "unprognostic (1.05e-3)" "unprognostic (6.79e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.39e-1)" "unprognostic (2.58e-1)" "unprognostic (1.28e-2)" "unprognostic (1.16e-1)" 17.6 17.6 17.4 13.8 21.3 25.0 13.7 32.7 28.3 15.8 16.0 15.6 7.1 15.5 14.5 12.6 20.3 12.4 14.4 20.8 17.1 22.4 15.7 21.7 17.1 17.5 17.0 22.6 14.0 14.9 25.0 19.2 24.1 18.1 13.9 17.9 14.9 18.5 11.7 23.9 21.6 18.2 17.1 13.4 26.3 13.3 30.8 14.4 46.5 17.4 8.4 14.1 14.2 15.7 1.7 2.0 10.6 3.1 1.4 3.0 1.0 28.7 13.9 23.3 13.5 15.5 15.8 22.6 16.2 31.2 15.6 14.3 15.0 11.8 11.7 10.0 23.1 18.1 19.7 11.0 31.5 24.3 7.9 3.1 17.0 10.4 11.2 17.7 17.5 22.9 15.9 21.2 16.6 34.0 12.7 17.1 15.5 7.2 22.8 20.4 15.6 18.5 4.9 12.7 11.0 14.4 7.4 19.9 11.2 11.3 20.6 17.6 10.9 19.1 13.9 18.7 23.8 17.2 11.8 21.9 22.4 25.3 7.0 9.6 15.1 13.9 22.6 13.9 11.7 17.8 4.3 2.9 7.5 2.4 2.6 2.1 1.1 2.0 3.0 2.0 1.7 2.0 1.5 10.6 1.4 3.1 1.6 1.3 1.0 17.4 21.3 32.7 28.3 17.1 22.4 17.0 22.6 18.1 14.4 29.8 26.1 16.6 27.4 45.2 58.2 34.8 17.8 13.4 17.0 17.4 56.9 22.4 10.0 21.7 114.4 21.8 32.1 0.0 28.0 43.2 22.6 25.0 17.3 20.3 19.0 135.1 25.8 23.9 27.9 40.1 12.0 22.7 33.7 24.4 23.3 27.6 35.4 22.6 18.7 11.5 40.3 12.9 20.0 34.2 22.5 35.9 35.9 24.1 20.4 35.8 GUCY2C "GUC2C, STAR" ENSG00000070019 "Guanylate cyclase 2C" P25092 12 14612632-14696585 "Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor" "Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 85.1" "Cell type enhanced" "Detected in some" 21 "Enterocytes: 37.2;Intestinal endocrine cells: 169.6;Mucus-secreting cells: 61.9;Paneth cells: 99.3;Undifferentiated cells: 41.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.9;stomach cancer: 9.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "memory B-cell: 4.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 3.7;BEWO: 2.2;CACO-2: 3.2;CAPAN-2: 4.6;SiHa: 4.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037655, HPA073759" Uncertain Uncertain Vesicles NA NA Vesicles "HPA037655: AB_10672388, HPA073759: " "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (3.58e-2)" "unprognostic (2.11e-2)" "unprognostic (1.60e-2)" "unprognostic (5.67e-3)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (1.58e-1)" "unprognostic (5.40e-2)" "unprognostic (2.35e-4)" "unprognostic (8.02e-2)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.98e-1)" 0.2 0.1 0.2 3.4 0.2 0.0 0.2 0.2 0.2 0.2 38.8 0.2 0.2 28.0 0.3 0.2 0.4 0.2 0.3 0.4 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.5 0.0 0.2 0.2 0.2 0.2 17.5 0.2 0.5 0.2 0.2 1.0 85.1 0.3 0.2 0.2 0.5 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 4.3 0.7 2.7 1.7 0.0 0.0 0.6 1.1 0.1 0.0 3.7 0.0 0.0 2.2 0.2 0.0 0.0 0.0 3.2 4.6 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.5 0.1 0.6 0.0 0.6 4.2 0.3 0.0 1.1 0.4 0.1 0.0 0.0 0.0 0.9 0.1 1.3 0.8 1.3 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.5 0.0 4.3 0.0 0.0 0.7 2.3 0.0 0.0 2.7 0.0 0.0 0.7 0.0 0.6 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.0 1.5 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 169.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 61.9 0.0 0.3 99.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 41.2 0.0 GUCY2D "CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, retGC, RETGC-1, ROS-GC1" ENSG00000132518 "Guanylate cyclase 2D, retinal" Q02846 17 8002594-8020339 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Sensory transduction, Vision" Lyase "Cone-rod dystrophy, Congenital stationary night blindness, Disease mutation, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "blood: 10.6;retina: 33.3" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 58.9;Rod photoreceptor cells: 55.6" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 31 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 53 "dendritic cells: 10.6" "Cell line enriched" "Detected in some" 4 "JURKAT: 11.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "unprognostic (3.57e-4)" "unprognostic (5.05e-1)" "unprognostic (1.49e-1)" "unprognostic (9.75e-5)" "unprognostic (5.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.44e-2)" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" "unprognostic (4.44e-1)" "unprognostic (7.59e-5)" "unprognostic (1.05e-1)" "unprognostic (3.46e-1)" "unprognostic (3.08e-1)" "unprognostic (1.07e-1)" 0.1 0.0 0.1 0.3 0.1 0.5 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 1.3 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.4 0.0 33.3 0.4 0.1 0.1 0.4 0.1 0.1 0.1 0.6 0.1 5.0 0.1 0.2 0.1 0.1 0.9 0.1 0.2 0.0 10.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.1 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.0 1.2 0.3 2.4 1.6 0.0 0.0 0.0 0.0 58.9 1.2 1.7 0.1 6.8 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.0 0.8 1.1 0.0 0.0 0.0 0.3 11.0 0.0 0.0 0.0 1.0 0.0 2.5 0.2 0.0 0.4 0.5 55.6 0.0 0.0 0.2 0.0 0.3 1.8 0.0 0.0 0.4 GUCY2F "CYGF, GC-F, GUC2DL, RetGC-2, ROS-GC2" ENSG00000101890 "Guanylate cyclase 2F, retinal" P51841 X 109372906-109482072 "Enzymes, Plasma proteins, Predicted membrane proteins" "cGMP biosynthesis, Sensory transduction, Vision" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "retina: 23.1" "Cell type enriched" "Detected in some" 33 "Rod photoreceptor cells: 33.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "THP-1: 4.5;U-266/70: 1.6;U-937: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 0.4" NA NA "unprognostic (1.91e-1)" "unprognostic (4.45e-2)" "unprognostic (2.96e-1)" "unprognostic (2.23e-1)" 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 1.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 7.5;lymphoid tissue: 26.7;testis: 26.7" "Cell type enriched" "Detected in single" 5 "Extravillous trophoblasts: 2.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027422, HPA030698" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA027422: AB_10601812, HPA030698: AB_2673575" "unprognostic (1.15e-2)" "unprognostic (2.78e-2)" "unprognostic (7.06e-2)" "unprognostic (2.14e-2)" "unprognostic (8.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (6.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "unprognostic (3.82e-3)" "unprognostic (0.00e+0)" "unprognostic (5.65e-3)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" 1.2 0.3 0.3 11.8 0.6 7.5 1.8 0.5 0.3 0.5 1.5 0.2 0.0 2.2 0.3 0.4 2.8 0.6 1.3 0.6 0.2 0.2 0.8 0.4 2.6 5.8 0.4 0.0 0.4 0.5 0.0 0.3 1.3 0.2 0.7 1.5 0.2 1.0 0.0 1.2 0.9 3.6 0.4 1.2 4.9 1.7 26.7 0.3 26.7 0.7 1.7 7.3 0.8 1.0 2.8 1.5 2.1 0.6 0.0 1.2 0.4 7.5 8.3 7.7 8.6 0.5 1.0 6.4 7.0 5.3 13.8 13.6 6.5 3.1 18.6 4.0 3.8 5.5 12.3 13.8 6.7 13.2 0.1 11.5 9.2 6.7 3.8 0.3 5.3 9.5 0.6 0.5 10.3 6.4 1.6 6.3 14.8 8.1 16.4 6.9 3.9 10.7 3.1 6.7 5.8 5.7 11.2 9.7 5.0 2.0 5.3 3.1 4.5 6.1 4.2 2.4 7.0 4.2 5.0 3.2 6.1 7.0 6.8 12.1 3.1 3.5 9.0 3.6 7.7 7.3 0.4 0.6 2.1 0.2 0.5 0.2 0.7 0.8 0.0 1.1 2.8 1.2 0.2 0.2 0.0 0.0 1.5 0.1 0.4 0.3 0.6 0.5 0.3 0.2 0.2 0.4 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052188-32101856 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 107.1;lymphoid tissue: 72.6" "Group enriched" "Detected in many" 8 "Hofbauer cells: 131.2;Kupffer cells: 133.2;Macrophages: 170.5;monocytes: 221.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 50.8;eosinophil: 62.5;intermediate monocyte: 96.5;myeloid DC: 31.6;neutrophil: 73.0;non-classical monocyte: 107.1" "Group enriched" "Detected in many" 15 "dendritic cells: 31.6;granulocytes: 73.0;monocytes: 107.1" "Group enriched" "Detected in some" 8 "THP-1: 23.1;U-937: 66.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005195, HPA063768" Approved Supported "Vesicles,Plasma membrane" NA NA "Vesicles, Plasma membrane" "CAB005195: AB_631619, HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 12.3 5.8 5.9 40.8 13.1 20.8 4.0 1.8 5.3 3.0 5.8 6.1 0.9 5.9 2.5 5.7 3.1 5.9 6.5 8.8 6.0 3.7 4.0 7.9 20.9 50.3 11.2 1.2 3.4 2.8 0.7 2.9 8.8 8.0 3.8 5.9 3.1 4.1 1.9 3.1 2.8 7.8 10.2 9.1 72.6 3.7 2.6 8.2 5.8 3.3 1.2 16.4 9.4 3.5 4.7 31.6 73.0 107.1 1.1 0.1 40.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.0 23.1 0.0 0.0 0.1 0.0 0.0 0.7 0.1 3.4 0.0 66.3 0.0 0.5 50.8 62.5 0.1 96.5 0.1 4.7 0.1 0.1 31.6 3.7 0.1 0.0 73.0 1.1 107.1 2.8 0.1 40.2 5.9 13.1 1.8 5.3 6.0 3.7 11.2 1.2 8.0 8.2 6.0 21.8 10.3 3.5 2.7 0.0 1.7 2.5 2.7 6.8 7.0 0.0 0.8 1.7 0.0 0.2 1.4 0.0 0.0 0.5 0.7 1.3 0.0 5.8 0.8 131.2 0.0 1.7 1.8 133.2 0.0 0.0 170.5 1.7 221.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 1.0 1.4 0.5 0.0 4.6 HIPK1 "KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2" ENSG00000163349 "Homeodomain interacting protein kinase 1" Q86Z02 1 113929192-113977869 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 90.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 62.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016664 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Nucleoplasm, Cytosol" Centrosome "HPA016664: AB_1850725" "unprognostic (2.98e-1)" "unprognostic (3.94e-2)" "unprognostic (4.89e-3)" "unprognostic (2.52e-2)" "unprognostic (6.47e-2)" "unprognostic (9.84e-3)" "unprognostic (4.64e-3)" "unprognostic (7.22e-2)" "unprognostic (7.52e-2)" "unprognostic (1.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (8.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.64e-1)" "unprognostic (1.94e-2)" "unprognostic (1.99e-2)" 15.1 16.8 21.2 14.7 23.0 90.1 13.6 38.1 20.4 20.4 14.4 20.7 14.5 10.2 15.5 14.2 18.7 27.3 17.5 27.9 22.9 17.2 14.8 13.8 19.3 14.7 15.0 16.4 18.7 16.8 20.7 23.8 13.8 21.3 14.4 15.2 20.7 13.0 14.9 19.7 18.5 13.4 15.1 18.3 15.9 14.8 33.5 21.3 47.2 23.3 13.1 15.5 17.3 26.7 2.3 6.2 9.8 4.2 4.3 6.0 2.3 8.2 6.7 9.3 7.1 10.9 5.7 6.3 5.7 6.9 8.1 7.8 7.7 3.2 11.1 7.8 9.0 3.0 5.6 12.0 6.6 11.8 8.0 6.0 16.1 8.4 8.1 9.1 12.8 20.0 6.2 9.7 10.4 10.6 7.7 12.0 19.7 11.0 12.0 11.6 62.4 16.8 7.3 9.5 6.2 6.0 10.2 27.3 3.9 7.3 7.1 4.1 5.5 10.4 11.2 7.3 10.8 6.5 18.5 11.6 8.0 10.8 13.0 8.6 7.5 5.8 9.6 9.0 10.4 18.2 3.4 4.2 8.2 5.5 3.7 5.2 1.7 4.9 4.9 3.1 2.3 5.0 6.0 9.8 4.3 2.6 6.2 3.6 2.3 21.2 23.0 38.1 20.4 22.9 17.2 15.0 16.4 21.3 21.3 50.6 37.0 12.9 14.8 54.6 47.6 27.1 22.9 64.3 20.5 26.2 66.8 9.7 5.0 12.5 82.7 29.3 18.8 70.0 18.3 7.9 25.0 26.7 45.1 33.6 19.9 69.9 35.7 23.9 54.6 73.8 20.4 35.5 20.3 15.4 24.2 28.9 17.0 17.3 35.0 13.4 60.3 25.8 37.0 35.4 26.0 70.4 11.9 47.3 22.4 23.0 HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777778 "Enzymes, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.1" "Cell type enhanced" "Detected in many" 4 "Horizontal cells: 209.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 17.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.8" "Cell line enhanced" "Detected in many" "HDLM-2: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007611 Supported Supported Nucleoplasm NA NA Nucleoplasm "HPA007611: AB_1850730" "unprognostic (1.35e-3)" "unprognostic (1.49e-2)" "unprognostic (1.65e-1)" "unprognostic (7.65e-2)" "unprognostic (5.50e-2)" "unprognostic (9.44e-2)" "unprognostic (2.76e-1)" "unprognostic (4.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.76e-2)" "unprognostic (3.42e-3)" "unprognostic (4.58e-2)" "prognostic favorable (9.99e-4)" "unprognostic (1.38e-1)" "unprognostic (7.82e-2)" "unprognostic (3.93e-3)" "unprognostic (1.03e-2)" 19.6 9.8 58.8 7.4 53.6 14.4 12.6 8.5 39.8 5.5 7.4 54.5 5.2 8.2 4.7 5.2 10.2 9.9 5.5 30.5 60.0 39.9 28.2 17.5 8.6 5.3 66.1 16.4 6.6 12.3 17.2 7.6 10.8 26.4 10.7 5.8 9.4 11.5 7.1 21.6 3.2 6.2 4.8 56.2 7.3 15.4 2.6 38.6 1.7 10.4 2.8 4.9 6.8 7.4 0.6 0.5 17.8 2.9 0.2 1.4 0.5 4.1 18.5 8.6 5.2 21.0 15.1 1.0 2.3 2.3 2.6 2.7 1.3 2.3 0.0 5.3 4.3 16.0 0.2 3.9 6.0 6.5 42.6 1.6 19.0 3.0 6.5 11.8 5.2 5.2 22.9 3.9 11.8 17.8 6.1 6.4 3.6 11.0 5.2 19.8 3.1 6.5 3.7 2.2 2.3 12.7 7.8 4.7 0.5 11.7 0.7 5.2 4.8 5.2 0.1 2.6 1.6 2.9 2.1 21.5 9.1 4.3 10.5 11.3 25.8 15.3 3.7 18.6 2.8 4.9 17.8 1.1 2.7 0.2 0.9 0.3 0.6 0.5 0.1 0.5 0.3 1.4 0.4 1.5 0.2 2.9 0.2 0.0 0.5 58.8 53.6 8.5 25.2 60.0 39.9 66.1 16.4 26.4 38.6 14.9 31.1 34.2 22.5 8.2 100.5 179.2 58.6 29.4 29.6 61.1 143.3 6.0 29.9 26.8 2.4 43.9 23.1 0.0 58.5 1.5 18.6 91.5 42.8 127.8 14.7 209.7 64.5 159.0 115.1 3.1 12.0 28.9 42.2 32.5 35.2 61.0 53.9 17.5 17.7 62.8 59.6 45.3 63.6 0.9 1.7 8.3 8.0 30.2 23.3 40.0 HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cardiomyocytes: 138.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028069 Approved Supported "Nuclear bodies,Cytosol" NA NA Cytosol "Nuclear bodies" "HPA028069: AB_10601815" "unprognostic (2.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.61e-1)" "unprognostic (5.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.78e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.78e-1)" "unprognostic (2.18e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-3)" "unprognostic (7.89e-3)" "unprognostic (1.80e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" 46.3 13.4 12.7 15.9 15.9 12.7 49.2 11.7 13.7 23.6 24.8 11.9 15.9 9.9 28.3 22.8 22.9 24.1 18.8 69.0 13.4 11.8 23.4 21.1 20.2 20.9 15.5 8.2 23.6 15.4 49.7 21.2 20.5 15.2 23.2 12.8 15.6 18.8 18.1 45.9 18.7 25.0 32.9 15.9 20.1 20.5 14.7 14.2 15.2 37.9 26.0 14.4 33.6 34.6 3.1 11.3 17.6 10.1 3.3 4.4 3.7 9.5 9.1 6.9 7.8 32.1 20.3 6.9 10.1 11.8 8.3 7.0 10.0 7.0 10.4 8.6 12.4 4.2 12.3 5.2 11.3 11.7 15.0 8.1 10.4 10.3 7.6 13.3 11.2 6.6 19.0 22.3 3.2 9.3 8.6 10.0 7.6 3.3 20.8 13.3 5.0 9.2 7.8 1.7 8.6 5.5 12.4 24.5 10.3 13.6 15.0 1.0 5.8 13.7 15.8 9.4 7.8 17.8 20.6 12.9 13.0 8.9 14.9 7.2 11.4 17.9 10.9 6.3 11.8 12.1 6.6 10.1 4.8 3.5 7.6 4.4 2.4 3.2 3.7 11.3 3.1 2.9 3.5 17.6 3.3 8.6 1.4 3.2 3.7 12.7 15.9 11.7 13.7 13.4 11.8 15.5 8.2 15.2 14.2 11.9 40.1 19.6 37.7 59.1 15.0 138.1 28.1 60.2 40.9 31.4 17.7 14.6 5.0 10.7 17.4 81.2 34.9 0.0 21.3 10.5 36.9 34.5 13.9 44.7 26.7 30.2 35.6 49.7 100.8 22.3 39.7 52.2 55.6 6.4 26.9 10.8 18.6 21.6 35.3 28.4 23.7 51.8 63.4 10.0 7.6 65.6 12.9 17.3 20.1 42.6 HIPK4 FLJ32818 ENSG00000160396 "Homeodomain interacting protein kinase 4" Q8NE63 19 40379271-40390187 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 34.7" "Group enriched" "Detected in some" 31 "Early spermatids: 64.9;Late spermatids: 23.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 3.1;AN3-CA: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "unprognostic (2.07e-2)" "unprognostic (6.25e-2)" "unprognostic (2.58e-2)" "unprognostic (5.53e-3)" "unprognostic (4.00e-2)" "unprognostic (1.36e-1)" "unprognostic (3.69e-2)" "unprognostic (2.52e-3)" "unprognostic (1.08e-1)" "unprognostic (7.48e-3)" "unprognostic (8.85e-2)" "unprognostic (9.09e-2)" "unprognostic (3.06e-2)" "unprognostic (8.71e-3)" "unprognostic (3.64e-2)" "unprognostic (2.03e-2)" "unprognostic (4.63e-2)" 0.3 0.1 2.3 0.3 7.4 0.2 0.3 1.2 5.7 0.3 0.3 0.3 0.3 0.2 0.4 0.3 0.5 0.2 0.3 0.8 2.9 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.1 0.3 0.4 0.3 1.4 0.2 0.3 0.3 0.3 0.3 0.1 34.7 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.0 0.7 0.0 0.4 1.1 0.3 0.1 0.1 3.1 0.2 2.4 0.2 0.3 0.0 0.7 1.1 0.8 0.4 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.2 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.5 1.2 0.3 0.3 0.2 0.1 0.4 0.3 0.0 0.2 0.7 0.1 0.1 0.1 0.1 0.4 0.1 0.3 0.3 0.0 0.4 0.0 0.3 0.4 0.1 0.0 0.0 0.4 0.1 0.6 1.3 1.3 1.1 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 2.3 7.4 1.2 3.5 2.9 0.3 0.3 0.3 0.3 0.3 0.0 0.0 0.0 0.2 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.2 0.5 0.6 0.3 0.0 0.0 0.0 0.1 HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873315-32044633 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Cholangiocytes: 17.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 10.6;BEWO: 13.0;RH-30: 14.4;SCLC-21H: 11.7;SiHa: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Nucleoplasm, Plasma membrane" "HPA027295: AB_2672203, HPA027372: AB_2672239" "unprognostic (9.09e-3)" "unprognostic (7.29e-2)" "unprognostic (1.42e-1)" "unprognostic (5.95e-3)" "unprognostic (1.99e-1)" "unprognostic (2.12e-4)" "unprognostic (4.00e-2)" "unprognostic (6.90e-2)" "unprognostic (5.07e-1)" "unprognostic (2.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "prognostic favorable (7.48e-5)" "unprognostic (8.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.69e-2)" 1.7 1.9 2.7 2.9 3.5 0.5 2.1 3.2 6.4 1.1 5.9 0.2 12.6 2.4 9.0 3.4 1.1 3.3 1.0 1.7 3.7 3.2 6.0 1.3 1.7 0.7 1.2 2.1 1.8 15.7 0.2 4.7 7.6 1.4 4.0 6.5 9.1 1.5 11.1 0.6 5.0 4.4 4.1 0.9 0.4 2.1 1.8 0.2 0.4 1.1 2.2 1.0 3.8 7.7 1.0 0.7 1.7 0.5 0.5 0.5 0.1 0.0 3.0 10.6 0.1 0.0 0.0 13.0 1.0 0.0 0.2 0.0 4.2 0.1 0.0 0.4 4.9 0.2 0.1 6.2 0.0 0.0 0.0 3.2 0.0 2.8 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.9 0.2 0.9 8.0 0.0 0.1 0.1 14.4 0.0 1.1 0.0 11.7 7.8 10.3 0.8 0.4 7.7 4.3 1.1 0.0 0.0 7.5 0.0 0.0 0.1 0.0 1.4 0.0 0.0 5.0 0.8 0.5 0.5 0.5 0.3 0.3 0.5 0.5 0.3 0.2 1.0 0.5 0.5 1.7 0.5 0.3 0.7 0.4 0.1 2.7 3.5 3.2 6.4 3.7 3.2 1.2 2.1 1.4 0.2 6.0 7.8 0.0 1.8 4.5 4.3 3.2 17.8 1.4 4.5 7.0 2.0 8.1 0.0 3.8 0.0 0.9 2.7 0.0 2.9 11.6 10.6 1.6 0.0 0.9 2.3 3.2 4.7 0.0 0.0 0.0 0.3 0.0 3.3 0.0 3.9 11.4 2.6 2.9 0.0 1.5 1.2 0.0 1.4 0.9 0.7 5.1 5.1 0.0 9.0 0.8 ICK "KIAA0936, LCK2, MGC46090, MRK" ENSG00000112144 "Intestinal cell kinase" Q9UPZ9 6 53001279-53061802 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000791, HPA001113" Approved Approved "Nucleoli fibrillar center" NA NA "Nucleoli fibrillar center" "HPA000791: AB_2732392, HPA001113: AB_1851385" "unprognostic (1.75e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.82e-2)" "unprognostic (1.17e-3)" "unprognostic (5.11e-2)" "unprognostic (1.18e-1)" "unprognostic (8.28e-2)" "unprognostic (8.12e-3)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (1.07e-1)" "unprognostic (2.26e-1)" 9.8 28.2 10.1 6.5 10.7 2.8 13.4 14.3 12.7 11.5 12.3 20.1 6.6 11.3 10.6 6.8 10.4 9.2 8.3 9.6 10.8 7.7 5.4 9.6 8.2 5.5 13.3 8.1 11.8 8.2 9.0 5.3 44.3 12.3 12.2 13.0 9.7 20.7 12.7 5.9 10.1 14.2 13.7 16.8 6.2 15.0 5.6 12.6 14.8 7.6 7.0 7.9 10.6 9.1 4.5 4.1 6.2 3.1 3.2 5.0 2.1 5.1 1.9 10.1 6.9 6.3 10.0 11.7 4.6 8.5 7.5 8.6 2.7 1.6 3.7 2.8 14.1 2.4 3.4 12.0 4.8 9.9 13.0 4.7 2.8 2.3 14.8 3.2 3.4 3.7 8.8 5.3 3.2 3.7 5.4 6.9 8.2 5.3 15.5 17.0 4.4 3.6 4.2 3.8 18.0 4.2 5.8 4.5 5.0 3.1 3.7 16.3 7.3 4.5 11.2 6.4 10.3 6.5 7.3 5.7 12.0 5.6 4.4 11.4 4.3 3.1 1.5 2.4 3.3 5.8 6.2 3.1 5.6 5.0 2.3 4.8 3.7 3.6 4.1 2.9 4.5 4.2 3.6 1.7 3.2 2.5 4.1 4.8 2.1 10.1 10.7 14.3 12.7 10.8 7.7 13.3 8.1 12.3 12.6 17.9 16.8 7.1 4.3 6.9 30.5 8.7 7.6 17.4 26.1 3.5 35.3 17.7 11.6 8.9 1.8 8.7 9.5 0.0 21.0 27.3 8.2 14.5 19.7 12.3 5.2 25.4 8.6 8.0 10.4 1.1 13.3 6.0 3.3 5.4 25.7 20.1 16.6 2.9 26.9 3.8 41.7 6.5 14.4 6.4 2.7 7.3 48.6 7.5 12.3 8.0 IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648971-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 7.7" "Group enriched" "Detected in many" 5 "granulocytes: 7.7;T-cells: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010268, HPA045563" Approved NA NA 36000 "CAB010268: AB_671792, HPA045563: AB_2679368" "unprognostic (1.30e-3)" "unprognostic (5.81e-3)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (2.05e-2)" "unprognostic (1.29e-2)" "unprognostic (6.87e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (8.56e-2)" "unprognostic (1.62e-1)" "prognostic favorable (3.75e-7)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" 8.4 12.7 11.5 5.9 13.5 16.3 18.5 23.0 15.7 15.3 13.4 10.4 22.7 4.2 15.3 16.3 9.2 18.9 7.7 11.6 11.7 7.3 17.0 2.0 11.0 4.9 8.0 11.8 23.2 22.5 4.7 13.8 17.5 9.5 21.7 7.2 16.7 12.5 23.2 9.1 13.0 7.5 18.1 8.0 7.3 10.7 12.0 11.5 10.7 16.1 7.0 5.6 12.8 21.6 1.0 0.4 7.7 0.6 1.0 2.9 0.7 3.2 16.3 11.4 0.2 5.7 4.2 7.6 3.6 7.3 1.2 1.0 7.0 8.6 0.8 10.6 7.1 8.0 15.5 5.1 14.8 1.0 0.0 5.1 12.3 18.2 14.0 5.0 6.5 1.3 6.5 7.0 2.1 10.0 4.3 4.0 1.3 0.6 2.9 5.6 23.0 2.5 4.4 10.6 5.4 0.9 4.0 8.9 2.9 3.4 20.0 3.8 17.1 26.2 1.5 14.1 25.7 8.0 3.0 11.1 1.1 14.7 2.9 5.7 1.0 4.4 2.7 2.2 4.8 2.7 4.0 0.6 1.8 0.9 0.6 0.6 0.4 0.8 0.3 0.4 1.0 2.9 1.0 7.7 1.0 0.5 0.3 0.0 0.7 11.5 13.5 23.0 15.7 11.7 7.3 8.0 11.8 9.5 11.5 26.8 11.2 0.0 25.0 29.1 51.6 25.7 10.2 38.8 31.8 21.0 86.4 26.8 1.7 13.8 23.0 23.2 5.1 0.0 9.4 16.8 24.2 51.2 0.0 0.4 5.8 71.5 33.7 38.1 7.0 38.8 16.7 5.0 20.3 2.8 21.9 47.2 25.3 10.5 12.7 18.6 32.3 0.0 17.6 3.3 13.6 28.0 23.0 3.2 20.4 39.1 IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332653 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 127.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Supported Cytosol NA NA Cytosol "CAB004447: AB_627785, HPA001249: AB_1079126" "unprognostic (1.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (1.95e-1)" "unprognostic (1.25e-3)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (3.02e-1)" "prognostic favorable (1.46e-6)" 9.1 10.8 10.9 17.0 16.7 9.3 10.0 26.1 16.9 10.3 10.3 12.4 11.4 4.7 15.3 13.2 17.9 16.4 14.9 7.9 13.1 6.9 12.4 9.9 14.9 12.2 20.3 7.9 9.6 13.3 18.0 13.6 11.2 11.9 14.0 10.9 10.5 11.4 9.7 17.6 22.2 9.8 16.4 10.5 18.7 10.8 8.3 18.6 12.9 14.3 8.4 17.1 18.1 12.8 12.6 14.8 14.1 9.6 11.9 11.2 5.8 3.6 12.9 3.7 6.3 14.3 12.4 4.7 3.2 11.3 9.5 8.4 2.9 6.7 7.1 5.5 8.8 9.0 4.1 5.0 12.7 12.3 6.9 5.7 9.9 6.0 2.3 10.9 1.9 10.4 8.2 9.7 9.1 14.2 18.7 14.0 4.7 8.4 3.5 20.8 4.1 6.9 3.1 3.6 11.8 4.1 7.1 6.3 4.1 10.7 3.3 1.1 2.1 2.0 3.6 5.2 6.9 4.8 8.3 7.2 6.7 3.5 5.2 2.3 2.1 2.1 5.0 7.9 4.7 7.6 14.1 9.6 10.4 10.1 7.6 10.3 9.4 10.5 11.2 8.9 12.6 10.2 10.4 11.4 11.9 9.0 14.8 9.9 5.8 10.9 16.7 26.1 16.9 13.1 6.9 20.3 7.9 11.9 18.6 11.9 24.0 17.7 29.3 21.6 11.3 4.5 15.3 14.7 13.6 15.7 127.6 8.6 1.7 11.4 2.0 27.7 11.8 0.0 11.8 4.6 9.8 23.2 36.9 10.2 15.8 17.5 10.9 15.4 26.9 3.0 15.3 17.7 18.6 13.6 15.1 11.6 13.3 14.4 12.0 4.8 52.3 6.5 6.4 2.6 6.4 25.5 12.7 20.3 13.6 25.7 IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 24.8;lymphoid tissue: 19.5" "Cell type enhanced" "Detected in many" 5 "Paneth cells: 20.1" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 25.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol NA NA Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (7.78e-3)" "unprognostic (7.37e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.34e-7)" "unprognostic (1.48e-2)" "unprognostic (5.77e-2)" "unprognostic (2.84e-3)" "unprognostic (2.84e-2)" 2.1 0.9 1.0 17.3 3.4 4.3 1.4 1.1 1.7 2.2 4.8 1.5 1.7 3.9 2.0 3.9 6.1 1.2 3.6 1.1 2.9 1.5 0.6 3.7 13.6 2.1 0.7 1.0 1.5 0.0 0.8 2.5 1.9 1.8 4.3 1.5 8.3 2.9 0.1 8.9 4.2 1.0 2.9 12.8 4.0 0.0 2.4 18.8 2.6 4.4 19.5 4.4 0.4 12.9 4.6 4.2 15.9 10.8 24.8 12.3 9.0 7.1 2.0 0.2 3.6 5.2 2.1 3.6 11.5 5.0 5.6 5.6 14.7 17.9 9.9 7.3 6.0 12.2 0.0 9.3 1.0 2.9 1.7 2.5 4.2 3.9 4.7 15.2 8.1 6.6 1.6 4.1 0.8 5.8 7.2 4.9 1.2 5.5 5.2 1.8 9.7 25.6 2.9 2.1 5.5 5.2 2.1 14.2 5.9 15.4 0.0 0.0 1.6 12.3 2.2 2.6 7.3 10.8 14.0 5.0 3.1 3.6 4.1 1.9 0.9 11.6 9.4 12.8 2.0 4.2 15.9 0.3 10.5 11.2 7.5 12.9 16.7 15.2 4.6 7.4 13.3 13.6 1.1 10.8 6.4 1.5 24.8 12.3 0.0 5.0 8.9 3.6 1.6 0.0 0.8 0.0 2.7 0.0 0.0 0.0 3.5 0.0 10.6 2.7 0.6 10.5 0.0 10.9 3.6 2.4 2.6 4.7 0.8 12.5 0.0 3.5 1.3 11.9 5.2 0.9 5.3 6.8 1.8 6.8 0.0 12.0 20.1 0.7 2.0 0.0 0.0 0.5 0.2 0.5 4.3 1.3 14.4 8.0 9.6 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 130000000 "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 20.9 17.6 11.0 22.3 11.9 7.5 37.0 9.4 14.6 40.2 75.1 14.7 41.9 13.5 75.4 25.2 35.7 33.2 41.1 35.1 11.1 9.2 21.6 15.1 21.9 18.9 11.5 14.0 24.2 22.3 20.4 10.9 22.2 11.5 39.9 24.6 19.3 19.4 89.9 18.5 12.4 22.2 103.5 10.6 20.2 33.2 14.2 11.0 8.2 17.5 14.1 13.6 60.8 25.9 19.5 45.9 76.5 49.4 45.3 25.8 63.7 23.9 18.5 29.2 10.1 45.2 32.1 13.3 35.3 69.8 41.8 51.0 19.3 28.3 9.0 9.4 57.7 41.0 19.3 16.3 29.9 42.0 15.7 14.8 13.0 17.7 15.0 30.3 10.4 14.9 30.8 14.1 28.2 21.6 42.9 39.8 7.8 11.9 10.7 54.5 18.0 9.2 17.8 18.4 20.4 21.8 9.6 15.3 9.6 30.6 19.2 5.1 11.5 16.7 23.1 19.4 29.8 16.1 11.9 46.0 52.5 23.7 21.7 17.1 7.8 4.8 12.7 38.9 15.7 24.4 48.3 49.4 76.5 25.8 47.9 25.1 19.5 23.3 24.4 45.9 17.1 14.7 18.5 31.7 45.3 44.4 18.5 25.7 63.7 11.0 11.9 9.4 14.6 11.1 9.2 11.5 14.0 11.5 11.0 41.7 17.0 28.3 58.4 44.9 13.9 0.3 66.2 18.7 15.9 54.1 7.9 94.6 49.7 120.2 46.5 56.1 64.4 46.7 108.6 153.9 93.0 39.7 29.0 24.9 111.6 7.9 36.5 84.1 50.9 110.9 66.2 80.3 81.0 196.6 43.0 50.2 101.4 57.5 138.6 74.7 29.6 155.2 137.9 31.1 15.7 37.8 92.0 54.3 41.7 41.9 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294034 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease mutation, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 64.5" "Cell type enhanced" "Detected in many" 4 "Peritubular cells: 230.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 8.8;granulocytes: 5.1;monocytes: 10.5" "Cell line enhanced" "Detected in many" "Karpas-707: 31.3;U-266/70: 23.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" NA NA 72000 Vesicles "Plasma membrane" "HPA036302: AB_2675048, HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.9 14.7 7.1 3.5 8.2 4.5 12.0 12.0 8.2 10.3 15.2 11.7 10.6 8.4 15.5 6.1 4.7 13.1 7.7 17.7 6.4 5.8 18.7 32.5 5.3 2.2 10.1 4.9 28.3 64.5 11.6 11.6 26.2 8.0 10.5 8.9 11.0 12.0 10.6 15.1 7.3 16.0 10.6 6.8 47.3 8.7 6.9 9.7 2.2 17.1 5.0 3.2 11.3 16.0 1.1 8.8 5.1 10.5 0.8 0.7 1.3 3.8 2.1 2.0 3.0 10.9 3.8 6.5 2.2 2.0 1.2 1.2 5.4 4.4 4.8 5.4 3.9 2.6 1.0 4.7 1.0 0.7 0.0 3.8 0.0 1.5 11.8 4.7 2.2 3.9 5.9 2.4 0.1 2.8 2.4 2.2 2.7 5.9 31.3 0.9 1.7 1.7 3.9 1.8 2.0 3.4 16.7 1.1 4.2 0.1 15.8 3.7 2.9 3.9 2.1 2.1 3.7 1.0 11.0 2.0 2.3 1.4 4.9 2.8 23.1 12.6 11.2 2.6 3.9 0.0 2.0 8.2 5.1 0.2 7.8 0.3 0.8 0.3 0.1 8.8 1.1 0.7 0.1 1.7 0.8 10.5 7.4 0.0 1.3 7.1 8.2 12.0 8.2 6.4 5.8 10.1 4.9 8.0 9.7 44.7 26.7 8.2 54.6 57.7 38.7 85.3 107.0 41.5 50.0 59.3 74.6 15.8 13.3 41.1 2.9 52.3 87.1 0.0 68.2 39.2 29.8 84.0 3.5 214.7 8.6 36.5 157.1 201.3 47.7 3.6 89.2 26.7 49.0 8.2 103.9 26.9 67.8 56.1 230.5 116.2 22.2 58.2 42.3 6.2 1.2 60.1 32.0 6.4 56.3 113.2 INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859018 "Enzymes, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.5;brain: 5.9;kidney: 8.3" "Group enriched" "Detected in some" 6 "Bipolar cells: 1.3;Cardiomyocytes: 1.7;Early spermatids: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 5.5;SH-SY5Y: 19.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA025285 Uncertain NA NA "HPA025285: AB_1851814" "unprognostic (1.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.42e-2)" "unprognostic (6.76e-4)" "unprognostic (1.51e-1)" "unprognostic (9.07e-3)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (5.57e-2)" "unprognostic (2.20e-2)" "unprognostic (7.00e-2)" "unprognostic (4.22e-5)" "unprognostic (2.82e-1)" "unprognostic (9.55e-2)" "unprognostic (2.75e-3)" "unprognostic (3.66e-2)" 0.9 5.5 0.0 0.3 5.9 0.1 0.8 1.9 1.4 1.9 0.1 0.0 0.0 0.1 2.7 0.1 0.1 0.6 0.3 1.9 0.5 1.3 8.3 0.1 0.1 0.4 0.8 0.6 0.3 0.9 0.1 1.7 0.4 5.6 2.7 0.1 2.1 0.6 0.5 0.4 0.1 0.2 0.3 0.0 0.2 3.0 4.2 0.4 0.3 0.3 0.0 0.8 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.5 19.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 1.4 0.5 1.3 0.8 0.6 5.6 0.4 0.0 0.0 0.0 0.0 0.0 1.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 IRAK1 "IRAK, pelle" ENSG00000184216 "Interleukin 1 receptor associated kinase 1" P51617 X 154010500-154019980 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Exocrine glandular cells: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004461, HPA054476" Supported Supported Nucleoplasm,Cytosol No No Cytosol Nucleoplasm "CAB004461: AB_2249106, HPA054476: AB_2682501" "unprognostic (4.46e-3)" "unprognostic (9.32e-2)" "unprognostic (1.71e-2)" "unprognostic (5.04e-3)" "unprognostic (7.09e-3)" "unprognostic (4.43e-3)" "prognostic unfavorable (3.03e-4)" "unprognostic (7.89e-3)" "unprognostic (3.36e-2)" "unprognostic (3.69e-2)" "unprognostic (1.95e-1)" "unprognostic (6.64e-2)" "prognostic unfavorable (2.06e-4)" "unprognostic (2.76e-3)" "unprognostic (2.36e-1)" "unprognostic (2.21e-3)" "unprognostic (3.04e-1)" 22.3 23.7 12.1 25.0 11.4 48.3 38.5 7.7 14.8 11.1 24.8 10.8 13.4 29.9 13.2 12.4 25.5 12.2 23.1 14.1 9.9 12.3 23.7 46.9 18.5 37.5 12.6 7.9 15.1 34.6 8.1 15.2 14.3 11.9 18.0 11.0 10.1 31.9 15.9 32.6 15.9 34.6 11.5 12.7 34.0 19.3 14.3 9.8 17.0 12.6 20.4 26.7 17.2 15.3 10.0 13.0 6.7 10.6 6.3 6.7 3.4 77.0 30.0 4.3 34.6 8.5 6.8 18.5 11.5 10.9 17.8 16.5 23.7 34.2 32.9 64.8 12.3 27.3 21.1 9.8 18.8 6.9 25.8 29.3 12.0 27.0 14.1 19.5 28.3 20.6 9.4 16.5 16.9 18.7 9.2 10.6 6.7 21.1 38.1 12.4 28.4 11.6 25.3 10.5 24.6 59.8 30.2 21.5 55.2 11.8 14.6 23.8 17.2 13.7 15.3 22.7 1.7 5.9 30.2 14.5 21.6 34.2 49.3 71.3 48.0 30.6 60.3 31.5 34.1 22.3 1.3 8.7 6.7 6.7 10.6 5.9 7.5 5.3 5.3 5.4 10.0 3.1 6.1 5.9 6.3 8.1 13.0 2.5 3.4 12.1 11.4 7.7 14.8 9.9 12.3 12.6 7.9 11.9 9.8 0.0 14.1 25.2 11.0 11.8 8.1 8.2 20.4 6.7 19.4 10.4 5.9 9.6 6.6 45.8 0.6 13.7 36.0 0.0 97.4 17.8 12.1 24.0 12.7 32.6 52.7 15.9 19.7 10.4 45.4 1.8 16.7 26.5 13.5 11.8 24.2 14.0 61.0 24.6 20.1 13.3 5.0 0.0 14.5 1.7 6.3 11.4 10.3 14.0 28.8 23.4 IRAK2 ENSG00000134070 "Interleukin 1 receptor associated kinase 2" O43187 3 10164865-10243743 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.7" "Cell type enhanced" "Detected in many" 7 "Basal glandular cells: 18.1;Glandular cells: 20.2;Urothelial cells: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 16.2;BJ hTERT+: 16.9;CAPAN-2: 17.1;GAMG: 30.8;RT4: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013483, HPA050520" Uncertain Approved Vesicles NA NA Vesicles "CAB013483: , HPA050520: AB_2681154" "unprognostic (1.31e-1)" "unprognostic (2.04e-2)" "unprognostic (1.46e-2)" "unprognostic (4.61e-3)" "unprognostic (8.71e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (1.89e-2)" "unprognostic (8.01e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.24e-1)" "unprognostic (3.10e-2)" "unprognostic (7.22e-2)" "unprognostic (4.38e-2)" "unprognostic (3.91e-2)" "prognostic favorable (6.60e-5)" 12.1 5.8 3.6 8.6 5.9 28.7 5.4 4.5 7.0 3.3 4.0 12.2 2.3 3.3 3.5 2.6 8.4 2.4 6.8 2.7 3.6 5.2 4.3 15.4 12.7 5.3 10.4 3.7 1.9 3.2 2.4 1.8 3.5 7.8 6.4 3.1 2.1 4.8 3.4 19.6 6.2 6.7 3.4 6.1 5.9 5.2 1.7 8.6 3.9 4.1 2.7 16.7 14.3 7.2 5.0 1.3 2.5 1.2 8.4 7.9 2.5 1.2 3.7 0.1 0.5 4.0 3.4 16.2 1.3 16.9 2.3 2.2 1.7 17.1 0.0 0.4 2.0 30.8 0.4 0.4 4.3 3.1 1.0 1.2 0.3 0.8 4.7 2.0 0.0 0.5 2.1 0.7 8.5 11.0 6.1 4.7 0.1 0.8 5.2 2.7 0.0 0.0 0.8 0.1 2.0 3.6 0.8 0.0 0.2 5.1 23.4 0.2 0.1 1.6 0.0 0.1 0.4 0.4 0.8 4.8 5.3 0.4 3.2 3.3 1.7 5.1 1.0 11.3 2.2 0.9 0.2 1.2 0.1 7.5 0.7 7.9 5.0 2.2 4.1 1.3 4.5 1.6 3.9 2.5 8.4 0.2 0.1 0.9 2.5 3.6 5.9 4.5 7.0 3.6 5.2 10.4 3.7 7.8 8.6 0.0 5.5 0.9 18.1 7.1 0.6 1.6 0.0 0.0 2.3 0.0 0.0 0.1 0.0 8.5 3.3 2.1 1.1 0.0 3.5 0.4 1.0 20.2 0.0 4.7 2.9 0.0 0.0 1.3 2.5 1.1 0.9 4.3 5.0 2.8 0.1 1.7 10.4 0.0 0.0 1.0 0.0 0.0 3.1 0.4 0.4 6.5 0.8 1.5 0.4 22.1 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66188879-66254622 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.0" "Cell type enhanced" "Detected in many" 14 "Ito cells: 36.2;Kupffer cells: 118.3;Macrophages: 66.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 5.6;classical monocyte: 13.1;intermediate monocyte: 13.2;myeloid DC: 6.2;neutrophil: 7.2;non-classical monocyte: 20.6" "Group enriched" "Detected in many" 12 "dendritic cells: 6.2;granulocytes: 7.2;monocytes: 20.6" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 12.4;HEL: 12.8;HL-60: 17.0;NB-4: 13.6;THP-1: 20.6;U-937: 14.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" NA NA Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 21.8 3.7 2.1 10.6 3.6 58.0 13.4 1.0 2.4 8.7 6.5 2.3 5.5 1.7 6.2 8.6 4.9 7.0 7.6 16.0 2.9 2.1 3.6 2.9 22.1 25.6 4.6 0.3 5.9 2.7 1.3 17.9 6.1 3.7 7.0 3.0 5.5 6.0 5.5 5.5 3.3 4.9 6.4 5.9 25.3 6.2 5.1 2.8 1.0 4.9 4.5 5.4 9.5 11.4 0.4 6.2 7.2 20.6 0.9 0.3 3.6 0.0 0.0 0.2 0.0 15.0 12.4 0.0 1.6 0.0 0.9 1.3 0.0 1.2 0.0 0.8 3.0 0.0 0.0 1.8 0.0 0.7 0.0 0.0 12.8 0.7 0.0 7.8 17.0 2.4 7.8 0.0 0.7 0.0 0.0 4.4 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.7 0.0 0.0 0.0 3.7 0.0 0.1 1.9 0.1 0.0 6.7 0.0 0.7 0.0 0.0 20.6 4.7 0.0 0.0 0.0 0.0 0.5 0.1 1.2 0.0 14.9 0.0 5.6 13.1 2.2 0.0 13.2 0.0 0.0 0.0 0.0 6.2 0.4 0.0 0.0 7.2 0.9 20.6 0.0 0.3 3.6 2.1 3.6 1.0 2.4 2.9 2.1 4.6 0.3 3.7 2.8 8.9 20.8 0.8 4.1 1.3 0.3 2.2 0.0 6.7 20.5 3.5 0.0 0.2 0.0 0.6 3.6 29.3 0.0 0.0 1.0 0.1 17.3 1.4 26.5 0.0 8.9 0.0 0.0 36.2 118.3 3.0 6.6 66.9 5.0 2.8 1.0 0.2 2.8 0.0 10.6 0.2 0.0 0.0 7.2 0.7 0.9 1.1 0.2 2.5 0.2 2.2 IRAK4 NY-REN-64 ENSG00000198001 "Interleukin 1 receptor associated kinase 4" Q9NWZ3 12 43758944-43789543 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016685, CAB022077" Uncertain Approved Nucleoli,Microtubules,Cytosol NA NA Microtubules "Nucleoli, Cytosol" "CAB016685: AB_1618505, CAB022077: " "unprognostic (2.76e-2)" "unprognostic (5.63e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.46e-5)" "unprognostic (6.15e-2)" "unprognostic (3.50e-3)" "unprognostic (1.44e-2)" "unprognostic (8.49e-2)" "unprognostic (6.44e-3)" "unprognostic (7.50e-2)" "unprognostic (4.00e-3)" "unprognostic (6.29e-2)" "unprognostic (4.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "prognostic favorable (4.42e-5)" 18.0 9.4 5.1 15.0 10.4 10.3 11.3 3.7 6.0 10.3 12.2 9.1 12.5 10.2 13.0 14.1 15.0 9.4 10.8 7.6 6.7 5.2 13.3 11.8 12.0 24.0 13.2 3.9 9.3 20.1 9.1 16.1 14.0 9.8 10.5 10.0 11.9 11.9 15.1 4.1 15.2 15.0 11.8 13.0 25.0 12.3 7.1 11.7 30.3 17.0 7.7 18.9 11.1 10.7 5.1 5.8 16.9 6.0 8.8 7.7 4.7 5.3 4.0 2.8 3.7 10.2 17.2 4.0 7.6 5.4 6.0 5.5 3.4 5.2 9.2 7.5 6.3 4.0 4.4 3.1 4.9 8.7 13.2 2.9 8.8 3.1 2.1 5.8 12.1 10.8 9.1 7.8 7.6 4.5 10.6 8.9 9.0 8.1 6.9 16.6 2.9 10.5 6.8 1.0 0.0 4.7 7.0 3.4 4.8 4.7 5.1 2.0 2.0 3.7 4.7 3.6 4.0 5.9 10.8 7.9 7.4 1.4 9.1 5.2 8.4 10.9 8.0 7.7 32.7 4.1 16.9 4.6 9.4 7.4 5.4 7.7 4.0 6.1 6.3 4.5 5.1 5.5 5.9 9.3 8.8 6.0 5.8 7.5 4.7 5.1 10.4 3.7 6.0 6.7 5.2 13.2 3.9 9.8 11.7 17.9 17.0 15.7 9.4 9.6 5.7 4.1 22.9 6.7 10.3 31.4 19.6 12.5 18.3 10.9 12.6 12.4 13.8 0.0 15.4 7.3 9.3 8.1 20.9 7.3 15.2 7.9 3.5 12.9 29.8 16.3 11.5 22.9 10.1 18.0 9.3 9.1 12.5 5.8 10.6 11.3 25.0 6.5 8.6 27.0 12.6 10.3 23.3 41.5 7.8 11.2 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255191 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "blood: 28.0;lymphoid tissue: 60.5" "Cell type enhanced" "Detected in some" 20 "Alveolar cells type 2: 10.4;granulocytes: 32.2;T-cells: 47.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 28 "gdT-cell: 13.8;MAIT T-cell: 9.1;memory CD4 T-cell: 19.5;memory CD8 T-cell: 18.9;naive CD4 T-cell: 28.0;naive CD8 T-cell: 22.8;NK-cell: 9.2;T-reg: 23.1" "Group enriched" "Detected in many" 29 "NK-cells: 9.2;T-cells: 28.0" "Group enriched" "Detected in some" 9 "JURKAT: 36.5;MOLT-4: 13.3" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 2.3 0.7 0.5 12.2 0.6 2.5 1.3 1.9 0.5 1.4 3.3 0.0 0.0 0.5 1.2 1.1 1.8 1.4 4.3 0.9 0.5 0.5 1.4 1.2 6.6 60.5 0.9 0.0 0.7 0.7 0.0 0.9 0.1 0.3 1.1 1.3 1.5 3.5 1.1 0.5 1.0 8.9 0.4 1.2 10.7 2.3 1.4 0.0 60.3 1.6 2.7 24.3 4.1 1.3 0.0 0.0 0.4 0.6 9.2 28.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 2.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 36.5 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 13.8 0.0 9.1 0.0 19.5 18.9 0.0 0.0 28.0 22.8 0.4 9.2 0.6 0.0 23.1 13.6 0.5 0.6 1.9 0.5 0.5 0.5 0.9 0.0 0.3 0.0 0.0 10.4 0.0 0.6 2.4 0.0 0.8 0.0 0.0 1.2 1.8 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.5 0.2 32.2 0.6 0.0 0.0 0.0 1.8 0.6 5.5 0.0 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 3.0 0.1 47.3 0.0 0.4 JAK1 "JAK1A, JAK1B, JTK3" ENSG00000162434 "Janus kinase 1" P23458 1 64833229-64966504 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 70.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013088 Approved NA NA "CAB013088: " "prognostic favorable (9.63e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.81e-4)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (4.21e-2)" "unprognostic (1.53e-1)" "unprognostic (7.00e-3)" "unprognostic (8.40e-2)" "unprognostic (7.88e-3)" "unprognostic (1.66e-2)" "unprognostic (8.84e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "unprognostic (3.51e-1)" 46.7 20.4 15.5 31.1 16.5 21.2 56.6 24.3 20.4 27.3 27.1 16.3 16.5 13.8 28.2 22.0 27.0 20.7 27.7 27.3 15.3 16.5 31.4 38.3 36.5 61.4 15.6 14.1 33.3 29.1 28.3 39.8 22.9 25.1 26.0 22.2 18.1 19.8 21.3 45.1 29.7 29.3 30.7 16.3 52.7 20.9 17.3 15.0 62.7 29.0 17.9 42.5 37.2 29.3 20.2 15.4 34.9 17.1 68.1 27.5 25.8 11.2 14.6 6.1 0.6 70.7 40.1 7.9 17.5 25.9 14.6 17.2 4.8 6.2 17.1 13.6 31.1 27.2 6.3 4.1 13.5 20.8 22.5 6.6 23.1 7.7 10.4 26.1 8.8 16.1 35.1 18.8 22.0 23.0 17.4 45.4 8.5 8.4 18.3 16.1 6.4 4.8 5.9 4.2 12.9 8.8 6.9 17.6 6.3 37.6 19.8 4.3 12.9 24.0 11.3 10.3 12.7 24.0 5.5 41.2 17.5 7.8 39.6 9.3 11.5 5.2 13.5 16.3 11.7 7.9 31.2 10.9 31.5 22.8 15.2 27.5 20.2 22.0 25.7 15.4 16.1 24.3 20.7 34.9 68.1 17.1 10.5 26.5 25.8 15.5 16.5 24.3 20.4 15.3 16.5 15.6 14.1 25.1 15.0 47.6 79.3 120.3 114.0 103.6 35.7 98.8 79.0 41.5 63.7 106.4 21.6 5.5 36.5 152.3 100.2 130.9 49.5 23.3 184.7 94.8 76.6 173.3 55.4 77.3 52.1 20.6 63.8 178.0 138.0 72.8 88.9 109.3 47.2 252.5 54.9 54.4 180.7 49.2 79.5 61.6 35.1 161.7 144.2 30.5 50.9 145.2 10.2 159.2 38.1 188.3 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5128183 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Kupffer cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 40.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 40.8" "Group enriched" "Detected in many" 5 "ASC diff: 19.4;HDLM-2: 27.4;HEL: 56.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708" "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 19.8 8.8 11.5 19.0 10.5 19.0 17.7 14.7 14.4 17.8 10.6 7.0 10.3 7.2 14.8 13.6 12.4 13.4 14.6 27.6 10.3 6.7 7.7 5.6 16.1 19.4 7.0 10.5 15.9 6.7 10.1 7.5 12.0 10.0 12.0 7.4 9.4 7.2 7.4 14.4 19.0 12.3 10.4 11.7 21.5 14.1 10.1 9.0 13.6 8.6 6.5 13.5 13.9 15.6 2.1 9.6 40.8 7.5 3.4 2.1 2.5 2.5 1.5 1.5 2.5 19.4 5.0 0.4 3.5 3.0 2.7 1.8 0.1 0.8 0.1 0.8 2.1 2.2 0.9 1.6 2.1 2.0 27.4 0.5 56.1 3.0 0.7 4.0 3.8 2.9 4.1 0.9 1.1 1.8 3.3 2.5 2.0 4.0 6.5 4.8 0.9 0.9 5.4 1.3 1.3 1.7 1.9 2.8 0.8 2.0 1.3 1.7 0.9 1.0 1.5 1.1 1.6 0.8 6.7 5.1 4.1 1.4 4.2 2.4 1.2 2.3 0.5 5.3 1.9 2.0 40.8 7.5 13.4 2.1 7.3 1.7 2.1 1.6 1.2 9.6 1.9 0.9 1.1 7.1 3.4 5.8 3.6 1.6 2.5 11.5 10.5 14.7 14.4 10.3 6.7 7.0 10.5 10.0 9.0 14.9 6.4 6.9 2.8 8.7 7.4 22.0 0.0 5.3 7.9 7.0 7.9 1.8 1.7 3.0 7.4 8.7 3.9 23.3 3.4 0.8 7.0 1.7 13.9 1.6 11.9 7.9 2.9 4.9 36.0 5.3 21.9 27.7 5.0 16.2 4.2 12.2 5.4 14.4 31.5 2.5 11.1 0.0 5.0 14.9 5.7 7.3 2.9 5.0 3.3 4.1 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 68.3" "Cell type enhanced" "Detected in many" 7 "B-cells: 18.2;Ito cells: 14.1;Peritubular cells: 13.8;T-cells: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 20.6;HEL: 9.2;HMC-1: 9.4;Karpas-707: 24.0;U-266/70: 9.3;U-266/84: 13.8;U-937: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.8 1.7 4.0 24.5 8.5 12.0 2.7 2.4 3.1 1.9 2.3 1.0 0.0 2.2 1.7 2.0 2.5 3.5 3.6 4.3 2.7 2.8 3.8 2.0 8.4 68.3 7.5 0.0 11.0 2.0 0.4 2.3 4.1 5.3 3.0 2.4 1.6 6.1 1.5 0.7 1.3 9.5 2.5 8.4 36.1 3.2 1.8 5.8 20.9 3.4 1.7 28.8 5.3 2.4 7.4 4.5 16.9 9.6 8.4 15.0 6.8 0.1 0.3 0.3 1.1 0.4 1.5 0.2 0.5 0.0 0.0 0.1 0.0 0.9 0.4 2.0 0.4 0.3 0.1 0.0 0.2 0.0 20.6 0.0 9.2 0.0 0.8 0.7 0.0 9.4 5.1 0.2 0.0 0.0 0.0 0.2 2.1 0.0 24.0 0.0 0.4 3.6 0.0 0.2 0.5 0.7 4.7 0.0 0.4 0.5 0.0 0.0 0.3 0.1 0.2 0.0 0.1 2.0 1.4 0.4 0.0 0.4 0.0 0.0 9.3 13.8 2.5 0.1 14.0 0.2 1.2 4.9 0.2 12.6 9.6 14.5 6.5 15.0 13.1 4.5 7.4 14.9 13.0 16.9 8.4 8.8 3.7 11.8 6.8 4.0 8.5 2.4 3.1 2.7 2.8 7.5 0.0 5.3 5.8 0.0 5.8 18.2 0.5 0.7 0.3 1.4 0.0 0.0 1.2 1.8 0.0 0.9 0.0 0.6 1.0 5.8 0.0 0.0 0.3 0.7 2.3 0.2 4.7 0.0 11.5 0.0 0.0 14.1 10.8 0.9 11.5 3.5 3.3 12.6 0.0 0.8 0.4 0.0 13.8 0.1 0.5 6.5 2.1 0.3 0.7 0.9 1.1 24.5 0.0 0.5 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.2;retina: 31.2" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 71.2;Early spermatids: 45.5;Ito cells: 50.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 4.3" "Lineage enriched" "Detected in single" 5 "T-cells: 4.3" "Cell line enhanced" "Detected in many" "CACO-2: 32.4;HEL: 19.8;OE19: 11.2;SH-SY5Y: 9.3" "Low region specificity" "Detected in many" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol NA NA 110000 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 5.5 4.3 12.7 2.4 14.1 0.6 4.2 1.8 35.2 4.0 3.8 3.7 0.5 2.7 5.6 2.3 9.6 4.2 3.1 12.1 17.6 3.9 2.6 7.3 2.9 1.1 4.1 15.8 2.3 11.9 2.5 14.4 6.8 9.4 3.1 2.1 31.2 2.2 5.4 23.5 1.5 7.2 6.4 3.6 8.0 11.5 2.2 2.4 0.0 5.3 6.7 3.1 2.9 4.1 0.1 0.0 0.9 0.0 0.1 4.3 1.2 0.3 0.6 3.6 0.7 0.5 0.1 4.7 1.4 0.9 1.4 0.6 32.4 2.5 0.1 0.4 3.6 2.2 0.2 0.8 0.0 1.1 0.0 0.3 19.8 0.3 4.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.5 1.6 0.0 4.5 0.1 0.4 2.4 0.0 0.0 2.0 11.2 3.2 1.0 1.6 0.0 0.1 0.3 1.2 9.3 0.4 0.3 0.3 3.6 0.7 0.1 8.2 4.1 1.6 0.6 0.6 0.0 0.3 0.0 0.5 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.3 0.0 0.0 2.4 0.7 0.9 0.1 0.0 0.0 4.3 1.2 12.7 14.1 1.8 35.2 17.6 3.9 4.1 15.8 9.4 2.4 3.0 3.8 0.0 1.4 1.4 71.2 33.4 17.8 8.1 0.0 15.7 5.9 7.3 1.7 4.7 45.5 26.9 30.6 0.0 7.2 0.7 4.8 2.8 3.5 17.4 0.8 0.0 9.2 50.3 2.6 34.6 3.4 0.7 3.3 0.0 12.2 5.4 3.9 20.4 31.1 2.4 2.7 19.4 14.6 1.9 1.7 1.0 11.9 0.7 10.0 1.4 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078259-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Endothelial cells: 100.3;Ito cells: 200.7;Muller glia cells: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 32.5;TIME: 36.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004028 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 7400000 "Plasma membrane" "CAB004028: AB_2212507" "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 19.7 6.2 1.8 4.4 3.1 0.4 20.5 1.1 2.2 11.4 6.0 1.8 11.5 2.3 28.8 10.2 5.2 9.5 6.2 12.1 2.3 1.7 7.8 10.4 13.2 14.1 3.1 2.9 6.0 8.1 8.0 6.8 34.5 3.9 9.5 1.4 27.6 7.1 10.3 5.3 3.0 3.8 7.7 2.6 4.4 4.2 5.3 1.2 0.5 20.0 5.3 3.0 4.4 12.0 0.1 0.1 0.7 0.0 0.2 0.2 0.1 0.0 0.0 1.7 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 3.8 0.0 0.0 0.3 0.0 0.0 0.2 0.2 32.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 1.8 3.1 1.1 2.2 2.3 1.7 3.1 2.9 3.9 1.2 0.0 8.2 7.5 0.4 2.3 7.4 4.8 0.0 6.7 30.7 0.0 0.0 0.1 0.0 0.5 0.8 100.3 0.0 0.0 0.0 0.1 1.9 0.4 2.3 1.3 0.4 0.0 0.0 200.7 14.5 0.6 0.0 1.0 6.8 0.0 0.0 229.2 0.3 0.0 0.4 0.0 6.0 0.0 1.4 0.2 0.2 2.4 0.1 0.0 0.0 0.4 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 65.5" "Group enriched" "Detected in many" 10 "granulocytes: 496.5;Melanocytes: 200.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 12.7;eosinophil: 10.0;NK-cell: 9.7" "Group enriched" "Detected in many" 6 "granulocytes: 12.7;NK-cells: 9.7" "Group enriched" "Detected in some" 13 "HEL: 48.8;HMC-1: 102.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 48000000 "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 8.1 1.6 9.5 6.6 11.8 3.7 65.5 18.3 12.0 12.1 10.3 6.5 10.2 5.8 8.9 4.2 9.9 2.5 15.5 2.4 36.0 4.4 9.4 1.1 13.8 3.8 3.6 6.0 28.5 2.1 1.3 2.3 6.2 5.7 9.6 10.4 20.7 12.9 6.9 1.3 14.6 8.9 10.2 3.9 3.2 12.8 4.0 4.5 0.4 28.9 4.3 4.9 9.8 12.5 0.0 1.8 12.7 0.9 9.7 1.9 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.6 0.9 2.6 3.2 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.5 0.0 2.2 0.0 1.2 48.8 0.0 0.0 0.0 0.0 102.6 0.0 0.0 0.0 0.0 0.0 5.7 0.8 0.6 0.1 0.0 0.0 0.2 0.4 1.4 0.0 0.0 0.1 0.0 0.0 0.0 4.8 1.2 0.4 0.0 0.0 0.0 3.0 0.0 0.5 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 12.7 0.0 10.0 0.1 0.0 1.9 0.0 0.3 0.7 1.8 0.0 0.0 0.0 0.8 9.7 0.9 0.0 0.0 0.1 9.5 11.8 18.3 12.0 36.0 4.4 3.6 6.0 5.7 4.5 6.0 34.8 1.4 1.1 12.7 0.0 0.4 5.1 0.0 5.7 3.5 0.0 0.0 3.3 0.8 0.0 2.4 0.0 0.0 0.0 0.1 1.3 0.5 496.5 0.0 0.3 0.0 5.2 1.8 0.3 0.0 1.1 3.1 200.8 0.0 0.3 2.4 0.0 0.0 0.0 0.6 0.3 0.0 0.5 0.0 8.2 3.3 0.2 2.2 0.3 0.3 KSR1 "KSR, RSU2" ENSG00000141068 "Kinase suppressor of ras 1" Q8IVT5 17 27456470-27626438 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 57.7" "Cell type enhanced" "Detected in many" 8 "Cone photoreceptor cells: 68.7;Late spermatids: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "eosinophil: 7.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 89.7;HEL: 32.2;HMC-1: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009623, HPA011215" Uncertain NA NA "CAB009623: AB_2265455, HPA011215: AB_1852649" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (2.60e-1)" "unprognostic (3.48e-3)" "unprognostic (2.90e-1)" "unprognostic (6.98e-2)" "unprognostic (1.92e-5)" "unprognostic (8.36e-3)" "unprognostic (1.32e-1)" "unprognostic (3.15e-2)" "unprognostic (1.12e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (1.00e-1)" "unprognostic (7.55e-2)" "unprognostic (1.74e-2)" "unprognostic (9.61e-2)" 10.5 9.3 15.3 12.5 16.0 9.5 7.7 20.5 18.5 15.5 6.1 20.5 7.0 5.4 17.9 7.0 15.5 9.3 21.2 7.0 17.5 7.0 12.4 3.8 12.4 8.6 18.3 12.5 14.4 57.7 7.3 8.9 29.4 16.2 7.9 5.9 19.8 4.7 13.4 17.5 13.8 7.6 13.7 12.0 12.2 5.1 11.5 19.9 5.2 16.3 3.3 9.4 8.9 13.5 0.9 1.1 7.0 4.1 1.5 1.1 0.7 1.0 4.2 2.6 1.3 2.2 1.6 15.4 0.9 2.1 1.4 1.7 12.7 0.1 1.0 2.2 1.8 9.8 0.6 2.6 0.5 0.9 89.7 2.8 32.2 4.1 5.2 3.9 0.4 22.2 1.9 0.9 4.2 0.1 6.1 8.1 1.4 16.8 0.1 0.8 1.0 0.4 1.2 1.9 0.9 0.7 2.0 14.6 0.7 6.0 0.7 4.1 2.7 5.2 1.2 1.4 7.3 0.1 1.7 7.6 0.4 2.0 1.2 0.7 0.1 0.0 0.0 0.4 1.8 2.4 0.0 1.9 7.0 0.7 4.1 0.7 0.9 0.3 0.4 1.1 0.4 0.2 0.2 2.2 1.5 2.0 0.1 1.1 0.7 15.3 16.0 20.5 18.5 17.5 7.0 18.3 12.5 16.2 19.9 6.0 4.3 1.4 3.5 2.7 12.4 1.1 0.0 17.4 14.8 14.0 68.7 15.9 3.3 1.4 26.8 7.0 4.9 0.0 4.5 17.5 9.9 1.2 0.0 1.0 5.7 9.5 6.3 12.3 6.5 33.8 1.4 5.3 8.5 5.4 1.3 7.1 2.4 3.5 2.1 2.5 28.7 0.0 3.4 2.1 5.3 5.3 16.2 5.7 0.6 7.1 KSR2 FLJ25965 ENSG00000171435 "Kinase suppressor of ras 2" Q6VAB6 12 117453012-117968983 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 27.4;pituitary gland: 24.6" "Cell type enhanced" "Detected in many" 21 "Bipolar cells: 48.8;Collecting duct cells: 153.5;Cone photoreceptor cells: 37.3;Horizontal cells: 44.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 7.3;SCLC-21H: 5.4;TIME: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035536 Enhanced NA NA "HPA035536: AB_10673485" "unprognostic (1.74e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (2.29e-2)" "unprognostic (9.11e-2)" "unprognostic (8.42e-2)" "unprognostic (6.91e-3)" "unprognostic (1.10e-2)" "unprognostic (5.78e-2)" "unprognostic (5.80e-2)" "unprognostic (2.05e-4)" "unprognostic (1.19e-1)" "unprognostic (9.28e-3)" "unprognostic (5.02e-2)" "unprognostic (5.68e-2)" "unprognostic (8.14e-3)" "unprognostic (5.74e-2)" 0.9 5.0 13.2 1.1 13.8 1.1 1.7 27.4 17.2 1.0 1.9 1.3 2.2 1.0 0.8 2.6 0.9 1.7 1.0 0.8 12.9 4.8 3.5 0.8 1.2 1.6 2.2 10.8 0.8 3.0 0.9 24.6 0.9 7.7 1.3 2.3 0.2 1.2 3.4 0.9 1.0 1.0 0.9 2.9 1.0 1.7 3.2 3.0 0.0 3.8 0.0 1.5 2.3 0.5 0.1 0.2 0.8 0.1 0.2 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.1 0.0 0.2 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 2.2 0.0 0.0 0.0 1.6 0.1 0.0 0.5 0.1 1.2 0.0 0.0 0.1 0.7 1.5 5.4 0.1 0.0 0.0 0.0 0.1 1.1 0.0 11.0 0.0 0.8 0.0 0.2 0.9 1.5 0.0 0.5 0.0 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.2 0.1 0.2 0.0 0.0 13.2 13.8 27.4 17.2 12.9 4.8 2.2 10.8 7.7 3.0 0.0 0.0 0.5 1.1 0.2 48.8 2.0 2.5 0.0 0.0 153.5 37.3 0.5 0.0 1.6 8.4 0.3 0.0 0.0 1.4 0.3 0.0 1.3 0.0 0.0 0.1 44.5 19.7 0.0 0.0 9.4 0.0 0.0 0.0 0.0 8.2 2.3 0.4 1.1 0.0 0.5 28.3 0.0 0.0 0.2 1.7 0.3 0.2 0.0 2.8 1.0 LATS1 WARTS ENSG00000131023 "Large tumor suppressor kinase 1" O95835 6 149658153-149718256 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031804 Approved NA NA "HPA031804: AB_10601688" "unprognostic (4.02e-3)" "unprognostic (3.80e-3)" "unprognostic (1.28e-2)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (2.09e-1)" "unprognostic (6.15e-3)" "unprognostic (1.29e-2)" "unprognostic (9.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (5.62e-2)" "unprognostic (1.92e-1)" "unprognostic (8.43e-2)" "unprognostic (2.63e-1)" "unprognostic (2.65e-1)" 15.4 12.9 17.6 12.5 17.6 19.4 14.7 38.4 16.9 15.9 13.6 17.4 9.5 10.1 17.7 11.8 12.2 14.6 11.1 11.7 15.1 8.8 11.5 11.1 12.7 12.6 18.2 8.8 23.6 12.2 22.3 21.8 17.2 15.5 16.3 12.5 14.1 13.8 11.9 12.4 12.8 14.7 15.8 13.0 13.5 11.6 10.6 19.6 20.5 12.9 6.5 12.8 14.7 14.7 7.4 4.6 9.5 11.4 4.2 8.9 2.9 6.1 4.9 10.3 14.6 9.8 12.8 7.9 8.2 8.3 8.9 8.9 7.9 5.4 10.0 8.4 11.5 7.0 8.7 13.5 8.8 14.1 9.3 10.8 20.3 6.2 7.1 9.1 19.0 14.8 8.5 14.2 10.1 17.3 9.0 11.0 8.8 24.9 10.3 8.7 7.4 9.8 7.8 6.1 5.7 4.8 9.6 12.4 4.7 8.2 8.8 6.9 11.0 11.6 8.5 6.1 7.2 8.7 16.4 13.6 7.1 11.2 8.4 13.2 8.6 9.5 11.6 6.5 10.7 10.4 9.5 4.2 6.6 8.9 7.7 8.0 5.8 7.0 7.4 4.6 7.4 6.0 7.8 2.9 4.2 11.4 4.1 6.7 2.9 17.6 17.6 38.4 16.9 15.1 8.8 18.2 8.8 15.5 19.6 11.9 17.6 9.0 9.7 14.4 19.3 8.9 17.8 13.4 13.6 7.0 17.7 8.2 1.7 7.3 18.1 13.1 11.6 0.0 5.7 9.8 11.4 13.8 13.9 12.2 9.5 12.7 16.1 20.9 12.6 5.2 12.7 11.0 13.5 5.4 12.3 10.4 8.1 11.5 24.4 5.0 21.0 19.4 10.5 7.1 8.7 15.7 11.0 13.6 11.1 11.2 LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973032-21061547 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039191, HPA049037" Approved Supported "Centriolar satellite,Cytosol" NA NA "Centriolar satellite, Cytosol" "HPA039191: AB_2676385, HPA049037: AB_2680609" "unprognostic (2.77e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (6.22e-3)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (1.84e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-3)" "unprognostic (4.48e-1)" "unprognostic (6.57e-3)" "unprognostic (8.03e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (1.66e-2)" "unprognostic (1.25e-1)" "unprognostic (7.97e-2)" "unprognostic (1.11e-2)" 22.9 13.0 3.0 8.6 5.7 12.8 33.0 7.9 3.7 16.6 14.0 6.8 9.3 2.9 21.2 12.7 15.1 11.0 20.6 14.1 5.4 2.6 12.4 11.0 19.8 10.9 5.2 2.4 17.4 10.2 5.0 3.5 18.3 6.3 13.7 4.5 16.7 8.0 11.1 23.0 9.3 7.4 34.6 7.5 15.2 10.4 27.8 5.2 1.4 17.2 13.8 7.0 20.3 28.0 0.1 1.5 3.3 1.9 1.3 3.1 0.5 3.4 3.8 8.5 5.1 10.0 13.2 7.8 11.4 11.9 12.0 10.3 10.8 5.2 0.0 5.6 17.4 4.7 5.0 5.0 5.2 17.8 1.9 1.3 6.3 4.8 8.1 15.5 1.7 2.2 19.5 9.6 7.9 5.3 6.0 16.7 1.4 1.1 0.2 15.1 5.9 0.2 5.9 2.0 3.5 1.8 1.5 15.1 0.0 8.5 1.6 0.1 0.0 9.0 6.0 11.9 7.7 5.1 3.2 21.0 12.8 8.5 9.3 7.2 1.5 0.8 0.0 3.0 1.9 9.7 0.4 1.9 1.8 1.6 1.5 3.1 0.1 0.2 0.5 1.5 0.0 0.1 0.3 3.3 1.3 0.6 0.1 0.0 0.5 3.0 5.7 7.9 3.7 5.4 2.6 5.2 2.4 6.3 5.2 38.7 6.9 2.4 13.7 29.2 0.0 20.6 15.3 12.0 11.4 5.2 0.0 18.7 3.3 8.7 94.1 30.9 3.2 0.0 6.4 7.9 22.8 18.0 4.7 14.5 9.0 0.0 0.0 43.0 13.7 6.2 23.6 16.6 16.9 0.0 1.6 4.5 14.9 1.7 32.5 6.4 0.7 6.5 25.9 6.7 13.7 22.1 40.2 4.4 1.0 9.4 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "blood: 112.2;lymphoid tissue: 153.0" "Cell type enriched" "Detected in many" 10 "T-cells: 207.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "gdT-cell: 83.4;MAIT T-cell: 77.5;memory CD4 T-cell: 86.1;memory CD8 T-cell: 90.2;naive CD4 T-cell: 97.0;naive CD8 T-cell: 91.3;NK-cell: 42.8;T-reg: 112.2" "Group enriched" "Detected in many" 13 "NK-cells: 42.8;T-cells: 112.2" "Group enriched" "Detected in some" 6 "JURKAT: 66.9;MOLT-4: 93.9;U-698: 54.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 2.6 0.7 0.4 28.2 0.5 3.8 1.3 0.3 0.5 1.7 3.9 0.5 0.9 2.2 1.1 4.5 2.3 1.6 3.8 1.0 0.4 0.4 3.0 2.3 6.6 34.9 0.9 0.5 1.2 0.8 0.0 0.8 0.7 0.6 2.2 1.9 1.3 8.4 1.3 0.9 1.0 16.5 0.7 1.0 28.9 3.5 0.7 0.5 153.0 2.9 1.5 27.1 5.8 2.1 6.1 0.5 2.5 0.3 42.8 112.2 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 11.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.9 0.0 0.0 0.0 0.0 93.9 0.0 1.0 0.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 54.1 0.0 0.0 0.0 0.6 0.3 0.4 83.4 0.3 77.5 4.0 86.1 90.2 0.3 6.1 97.0 91.3 2.5 42.8 0.3 0.5 112.2 109.3 0.4 0.5 0.3 0.5 0.4 0.4 0.9 0.5 0.6 0.5 0.0 16.0 20.4 0.9 4.0 0.0 1.1 2.5 2.7 2.3 3.5 0.0 0.2 0.0 0.3 0.1 1.6 0.0 0.0 0.4 0.1 2.0 0.8 4.7 1.0 0.3 0.0 2.4 3.7 4.9 0.0 0.0 0.6 3.3 0.0 0.0 0.0 2.7 0.0 0.4 1.1 0.0 0.0 0.9 3.7 1.9 2.8 0.3 207.5 0.4 1.0 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.2" "Cell type enhanced" "Detected in many" 6 "B-cells: 22.9;Hofbauer cells: 25.0;Horizontal cells: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028516, HPA073571" Approved Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles, Cytosol" "HPA028516: AB_10601751, HPA073571: " "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 8.8 8.6 31.6 18.2 18.6 6.3 7.4 14.3 44.1 11.5 6.6 7.1 6.6 6.9 7.3 5.3 6.4 6.0 10.8 6.3 26.8 32.9 5.2 2.6 12.5 22.0 33.4 22.2 12.1 8.1 4.0 7.2 8.0 45.2 6.1 4.7 4.8 18.1 9.6 10.9 6.8 7.2 7.6 10.8 18.4 7.8 10.4 6.5 4.3 7.5 3.7 18.1 14.1 7.2 4.6 8.6 3.8 7.7 6.9 2.4 3.1 17.0 13.3 10.2 16.9 13.5 18.3 7.4 10.6 10.2 8.6 9.6 7.7 16.9 10.6 4.8 13.0 28.9 10.3 3.8 6.5 3.3 18.3 6.7 7.8 4.5 8.8 15.5 5.9 28.7 18.1 5.9 6.9 3.6 26.0 12.8 7.7 5.2 3.4 10.7 14.9 5.1 10.7 19.3 6.0 8.4 7.4 15.8 6.6 9.6 3.7 4.0 9.3 6.8 16.4 8.5 11.7 5.2 5.4 15.2 13.7 12.8 35.4 17.0 3.8 4.3 19.4 50.9 4.3 9.3 0.1 6.5 3.8 2.4 7.7 1.8 4.6 0.6 1.5 8.6 2.4 0.2 0.7 0.7 6.9 4.7 0.8 0.4 3.1 31.6 18.6 14.3 44.1 26.8 32.9 33.4 22.2 45.2 6.5 3.0 2.4 22.9 4.6 2.6 5.6 2.7 7.6 2.7 3.4 1.8 2.0 2.2 0.0 6.6 0.6 3.0 0.9 0.0 5.6 5.4 7.5 5.1 5.7 1.1 25.0 33.4 2.4 2.5 10.7 1.5 6.6 14.1 3.3 10.0 2.1 3.1 10.2 2.9 5.6 1.5 3.1 0.0 2.1 1.9 12.4 2.8 3.1 10.1 2.5 6.2 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Syncytiotrophoblasts: 96.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 14.7;neutrophil: 37.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 37.2" "Cell line enhanced" "Detected in all" "BEWO: 37.6;hTCEpi: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes Nucleoplasm Cytosol "CAB019313: , HPA008183: AB_1079252, HPA053882: AB_2682291" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 9.4 6.6 23.5 23.6 26.2 29.4 17.0 9.9 16.8 11.0 20.9 15.6 10.7 13.1 12.9 8.7 33.7 22.1 28.7 6.0 15.4 10.7 15.4 19.9 21.6 18.1 20.8 7.2 11.4 19.9 20.0 12.8 64.3 23.3 17.1 22.1 10.1 25.7 16.2 9.7 36.7 13.3 10.1 28.3 17.4 18.5 16.8 17.9 12.4 25.8 15.6 15.3 13.1 20.0 1.0 1.6 37.2 1.9 2.4 5.6 1.6 7.0 1.1 4.9 2.7 2.1 2.5 37.6 4.6 2.2 4.7 4.0 6.0 3.3 6.9 8.3 7.0 2.2 14.3 5.7 24.5 2.9 5.0 6.2 5.0 5.5 6.5 3.2 9.2 9.2 4.0 69.7 3.8 11.5 32.0 11.9 5.6 2.7 5.0 6.4 5.5 5.6 3.1 4.6 18.2 1.8 7.4 8.3 3.8 5.4 16.7 6.3 5.6 3.5 22.6 9.3 15.9 18.8 3.7 7.2 4.2 6.6 2.3 4.3 2.8 4.1 6.0 2.6 4.3 1.8 2.1 1.9 14.7 1.3 1.3 2.4 0.8 2.3 1.7 0.7 1.0 2.3 1.8 37.2 2.4 0.5 1.6 5.6 1.6 23.5 26.2 9.9 16.8 15.4 10.7 20.8 7.2 23.3 17.9 29.8 17.0 3.0 42.2 31.9 7.0 19.8 12.7 33.5 28.4 5.2 19.6 59.9 3.3 10.9 1.0 19.3 16.9 0.0 38.9 46.0 10.8 19.1 23.1 6.8 15.7 3.2 12.7 12.9 7.9 1.3 4.0 11.8 3.3 2.8 41.8 15.6 22.5 10.5 4.2 8.1 23.2 19.4 4.1 9.8 10.4 34.3 96.6 8.7 49.0 20.7 LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106885-98209633 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 4.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: AB_1079259, HPA041836: AB_2677698" "unprognostic (7.36e-2)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.60e-3)" "unprognostic (2.47e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.23e-1)" "unprognostic (4.96e-1)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.23e-1)" "unprognostic (4.65e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (2.16e-2)" "unprognostic (6.38e-3)" 5.1 10.3 13.7 5.6 21.3 17.3 5.6 16.6 34.3 7.3 13.8 6.1 5.6 12.6 6.1 6.3 12.7 6.4 7.9 16.9 11.0 10.1 10.1 8.5 10.0 5.1 7.5 18.9 8.0 21.0 22.2 10.0 4.8 13.2 7.9 11.8 5.4 10.5 6.5 17.5 11.5 13.8 5.7 5.5 6.8 9.4 8.0 6.9 7.2 8.7 5.7 7.4 8.3 8.1 0.6 0.7 4.8 0.9 0.3 1.6 0.5 9.8 11.6 9.0 9.2 4.8 3.9 8.4 4.1 4.5 4.0 4.9 9.1 9.0 5.2 11.8 5.2 15.3 10.8 10.4 6.3 6.3 7.4 7.3 3.5 10.4 9.1 5.9 6.2 6.3 2.6 8.7 8.3 11.3 4.1 6.0 6.0 9.1 10.9 3.6 13.3 6.6 3.7 11.0 13.5 5.7 7.2 6.1 10.2 6.7 17.3 6.5 12.9 8.2 15.0 6.0 9.5 4.1 2.5 7.3 8.4 13.8 16.8 9.3 4.9 8.5 10.3 5.7 4.9 10.0 1.2 0.6 0.5 0.8 0.3 0.5 0.6 0.9 0.9 0.3 0.6 1.1 1.6 4.8 0.3 0.9 0.7 0.8 0.5 13.7 21.3 16.6 34.3 11.0 10.1 7.5 18.9 13.2 6.9 26.8 10.5 0.0 4.2 8.7 14.0 18.7 17.8 10.7 9.1 1.8 13.7 2.3 1.7 5.0 0.8 3.1 26.2 0.0 7.9 1.6 3.5 6.2 2.3 6.8 1.8 6.4 11.5 3.1 2.6 2.1 1.7 2.3 1.7 0.0 13.5 5.8 8.6 13.1 4.2 2.4 9.9 0.0 3.8 6.3 4.7 9.5 2.5 2.9 12.6 13.2 LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513189 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 38.1" "Cell type enhanced" "Detected in many" 10 "Distal tubular cells: 21.6;Ductal cells: 19.4;Horizontal cells: 17.5;Urothelial cells: 44.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 8.6;SK-BR-3: 10.2;U-266/70: 9.5;U-266/84: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Supported Uncertain "Nucleoplasm,Cell Junctions" NA NA Nucleoplasm "Cell Junctions" "HPA040203: AB_10671690, HPA077070: AB_2732330" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (5.37e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-3)" "unprognostic (5.71e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-8)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-2)" 1.3 4.4 19.8 2.3 28.6 2.0 2.0 20.0 38.1 2.0 1.5 6.0 0.2 6.2 1.4 1.5 2.3 1.6 1.9 1.7 17.2 11.1 2.5 1.3 3.2 2.2 6.5 23.8 1.3 2.1 8.5 6.1 2.1 12.5 3.5 1.2 1.6 5.2 3.1 1.2 2.4 4.0 1.2 6.6 1.8 2.9 1.5 10.3 0.0 2.3 0.0 2.2 1.6 1.2 0.0 0.0 0.0 0.2 0.0 0.4 0.1 4.6 3.1 0.4 0.0 0.0 0.0 4.5 0.0 0.3 0.0 0.1 2.2 3.7 1.7 1.3 0.0 1.2 2.2 0.3 1.6 0.0 0.0 1.2 0.2 0.3 0.7 0.0 0.0 8.6 0.2 0.9 0.0 0.0 2.0 0.1 2.8 1.4 2.9 0.0 3.1 0.6 0.8 1.1 2.4 0.9 3.9 0.0 1.3 1.1 0.8 0.7 2.9 0.1 10.2 0.0 0.6 3.9 0.2 0.1 0.0 0.8 0.1 0.0 9.5 7.7 0.4 0.2 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 19.8 28.6 20.0 38.1 17.2 11.1 6.5 23.8 12.5 10.3 3.0 1.7 0.8 9.2 0.5 16.4 2.2 2.5 4.0 4.5 7.0 0.0 4.3 21.6 19.4 0.1 0.0 0.7 0.0 0.4 2.5 0.9 15.7 0.0 0.0 1.0 17.5 0.0 1.3 0.3 0.0 0.6 0.3 3.3 0.0 1.0 7.3 10.7 0.0 0.0 0.6 1.9 0.0 0.7 2.4 1.3 1.6 5.7 0.0 0.6 44.3 LRRK1 "FLJ23119, KIAA1790, RIPK6, Roco1" ENSG00000154237 "Leucine rich repeat kinase 1" Q38SD2 15 100919215-101078254 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 26.3" "Cell type enhanced" "Detected in many" 5 "Leydig cells: 30.0;monocytes: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "eosinophil: 3.2;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 23.5;Karpas-707: 17.3;U-266/84: 15.6;U-698: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010537 Uncertain Supported Mitochondria,Cytosol NA NA "Mitochondria, Cytosol" "HPA010537: AB_1079283" "unprognostic (3.74e-2)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (3.72e-1)" "unprognostic (6.68e-2)" "unprognostic (6.35e-2)" "unprognostic (1.94e-1)" "unprognostic (4.75e-2)" "unprognostic (3.43e-2)" "unprognostic (3.34e-2)" "unprognostic (2.95e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.92e-2)" "unprognostic (1.82e-2)" "unprognostic (3.13e-1)" "unprognostic (5.25e-2)" 6.1 1.9 4.5 26.3 3.9 6.5 5.0 2.1 8.1 6.4 8.0 5.9 2.2 2.9 7.9 6.0 5.4 7.1 4.2 3.4 4.0 1.5 2.7 1.0 4.7 15.0 4.5 4.0 6.3 5.3 2.8 2.3 4.4 2.5 7.1 6.5 2.8 7.7 6.8 1.6 7.3 8.5 5.7 3.7 11.1 3.9 5.1 3.4 1.2 3.5 2.1 17.4 7.5 6.7 2.3 3.3 3.2 1.1 0.0 0.0 0.1 0.8 4.8 0.0 0.0 7.4 7.6 0.0 2.9 2.1 2.7 1.9 0.8 2.1 23.5 1.1 7.8 0.0 4.8 0.7 0.5 1.4 0.4 1.1 7.1 1.1 0.0 0.5 3.8 5.5 6.0 1.0 1.7 1.5 0.7 4.7 0.0 1.2 17.3 0.5 0.0 0.0 2.4 0.2 4.3 2.0 1.7 0.4 6.4 0.0 0.0 0.0 1.7 1.8 2.7 5.4 0.0 0.3 4.6 5.4 0.0 0.8 1.0 0.0 8.8 15.6 15.2 0.3 0.5 4.4 0.0 0.7 3.2 0.0 0.3 0.0 2.3 0.0 0.0 0.9 1.5 0.0 0.0 0.8 0.0 1.1 3.3 0.0 0.1 4.5 3.9 2.1 8.1 4.0 1.5 4.5 4.0 2.5 3.4 14.9 12.8 11.9 6.5 2.9 0.6 2.8 2.5 8.1 7.9 0.0 5.9 8.4 0.0 3.6 3.0 5.7 12.0 0.0 2.7 3.1 3.5 6.3 1.1 0.0 9.5 0.0 13.2 12.3 14.3 2.4 30.0 14.0 3.3 32.5 12.8 0.8 6.7 10.5 20.1 0.3 0.4 6.5 2.1 5.2 1.1 3.0 3.0 0.5 10.8 9.3 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 40.4;lung: 50.4" "Cell type enriched" "Detected in many" 5 "Alveolar cells type 2: 391.0" "Group enriched" "Detected in many" 7 "lung cancer: 5.3;renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "neutrophil: 40.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 40.4" "Cell line enhanced" "Detected in some" "A549: 9.9;ASC TERT1: 10.2;BJ hTERT+: 5.7;RPTEC TERT1: 10.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 3.7 3.4 2.3 7.0 3.9 8.6 3.0 1.7 5.0 5.1 4.5 1.7 2.6 0.7 5.3 2.9 5.3 3.8 4.5 4.0 1.8 1.4 10.6 4.5 50.4 6.8 2.2 3.6 5.8 3.3 10.9 2.5 1.0 1.9 3.6 1.6 3.3 4.2 2.0 5.6 2.6 3.4 6.7 4.9 8.6 2.7 1.2 2.4 0.5 3.9 2.7 4.9 4.6 6.8 0.9 1.5 40.4 5.8 0.0 0.0 0.8 0.0 9.9 0.1 0.0 3.9 10.2 0.1 2.1 5.7 0.4 0.3 0.0 0.0 0.0 0.0 1.9 0.3 0.0 0.3 0.0 0.4 0.0 0.8 0.3 0.2 0.0 0.7 0.5 0.1 2.5 0.7 0.0 0.2 3.8 0.6 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.2 0.0 0.1 0.0 0.0 0.0 10.9 0.0 0.1 0.6 0.0 0.2 2.8 0.3 2.8 2.2 1.4 1.2 1.1 1.2 0.7 0.0 0.0 0.0 2.4 0.0 0.5 0.0 5.8 1.2 0.0 3.1 0.0 0.9 0.0 0.0 1.5 0.9 0.0 0.0 40.4 0.0 3.0 0.2 0.0 0.8 2.3 3.9 1.7 5.0 1.8 1.4 2.2 3.6 1.9 2.4 29.8 391.0 17.5 1.5 2.2 7.5 6.9 5.1 5.3 30.7 26.2 0.0 0.0 1.7 0.8 0.4 4.5 0.0 0.0 2.3 0.1 9.4 0.6 12.8 7.8 4.6 44.5 0.0 9.2 74.8 0.0 17.5 19.9 11.8 10.8 0.0 11.0 1.1 0.0 11.3 15.2 0.9 0.0 3.9 0.2 0.4 2.8 0.3 0.8 0.0 0.5 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503638-41513887 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 15.1" "Cell type enhanced" "Detected in many" 11 "Enterocytes: 13.4;Ito cells: 14.7;Mucus-secreting cells: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "MAIT T-cell: 8.3;plasmacytoid DC: 7.0" "Group enriched" "Detected in many" 10 "dendritic cells: 7.0;T-cells: 8.3" "Cell line enhanced" "Detected in some" "HEL: 5.4;NB-4: 10.5;RH-30: 5.1;THP-1: 16.1" "Low region specificity" "Detected in many" HPA059545 Approved Vesicles NA NA Vesicles "HPA059545: AB_2684057" "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 1.0 0.5 0.5 5.1 1.6 3.1 0.5 2.0 3.2 0.6 8.2 0.5 1.9 10.6 1.3 1.1 1.2 0.3 2.0 2.2 0.5 0.1 3.5 4.3 15.1 0.6 0.5 0.5 1.0 0.5 1.0 0.7 8.9 0.5 0.7 4.8 4.3 11.7 0.5 2.0 0.9 10.7 0.5 0.5 5.5 8.3 2.4 0.8 0.5 0.7 0.5 2.2 0.6 0.7 0.7 7.0 0.0 0.0 0.0 8.3 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.1 0.6 1.0 1.3 2.4 0.0 0.0 0.1 0.7 0.0 0.0 2.9 0.0 0.4 0.2 1.4 5.4 0.0 0.0 2.4 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.0 2.0 0.0 2.1 0.0 0.0 10.5 0.4 2.0 0.2 0.2 5.1 0.2 0.0 0.0 0.5 3.4 0.1 0.2 0.0 3.0 0.2 16.1 0.0 0.0 0.2 0.2 0.1 0.4 0.2 0.2 0.0 0.5 0.9 0.0 0.0 0.0 0.6 0.0 8.3 0.7 0.5 1.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 7.0 0.0 0.2 0.5 1.6 2.0 3.2 0.5 0.1 0.5 0.5 0.5 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.6 5.1 4.0 1.2 0.0 0.0 0.2 0.0 0.0 2.1 0.1 13.4 0.0 0.2 1.1 0.2 0.0 0.0 0.2 0.1 0.0 1.7 14.7 3.2 1.7 0.0 0.0 3.3 0.0 7.8 0.0 0.5 3.5 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.1 0.3 1.3 2.8 0.0 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879813-56014168 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.9" "Cell type enhanced" "Detected in many" 6 "Hofbauer cells: 110.4;Kupffer cells: 161.3;Macrophages: 122.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 36.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 57.7;HMC-1: 58.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 11000000 "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 8.8 6.8 4.5 34.0 6.3 33.6 11.1 9.5 4.1 5.3 10.5 5.8 7.2 15.6 3.4 7.8 7.2 6.7 13.7 8.9 4.8 3.6 6.1 13.8 34.6 70.9 7.7 2.1 5.3 9.8 3.1 4.9 19.1 5.6 5.7 6.6 6.3 14.9 8.5 2.7 3.4 16.2 6.6 8.5 69.4 7.4 3.6 5.1 3.8 9.4 5.3 25.8 10.7 7.5 8.4 9.2 36.8 26.5 1.9 0.9 2.7 12.8 7.7 1.8 0.3 0.1 0.0 13.9 9.8 14.5 6.2 4.4 5.3 4.4 12.4 4.4 3.9 4.8 6.0 7.2 7.3 5.3 20.1 7.2 57.7 2.3 1.9 1.9 5.8 58.6 0.3 2.5 0.1 4.5 3.6 8.3 0.0 30.5 26.9 0.9 0.7 0.0 6.1 11.1 20.2 0.9 0.9 2.8 1.5 4.0 6.1 1.2 22.3 4.9 0.0 2.0 13.8 1.1 13.6 9.7 0.0 2.9 0.0 4.4 9.0 3.3 28.1 0.6 11.5 0.4 2.1 7.2 12.3 0.9 16.8 0.7 8.2 0.2 0.3 6.4 8.4 0.1 0.4 36.8 1.9 26.5 9.2 0.0 2.7 4.5 6.3 9.5 4.1 4.8 3.6 7.7 2.1 5.6 5.1 32.8 35.7 89.3 18.6 4.7 2.1 1.4 17.8 22.7 31.8 8.7 2.0 2.5 0.0 18.6 0.6 18.5 14.9 0.0 44.9 61.3 8.4 36.9 70.5 10.9 110.4 0.0 5.8 25.8 161.3 1.7 3.1 122.4 5.0 73.1 13.5 61.7 37.6 13.5 1.1 1.3 1.5 19.4 4.3 0.2 1.2 5.1 32.4 24.5 12.3 92.1 MAK "dJ417M14.2, RP62" ENSG00000111837 "Male germ cell associated kinase" P20794 6 10762723-10838555 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 38.1;testis: 19.3" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 347.5;Early spermatids: 112.5;Rod photoreceptor cells: 298.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 7 "pons and medulla: 10.6" "Cell type enriched" "Detected in single" 13 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 14 "granulocytes: 11.7" "Cell line enhanced" "Detected in some" "HDLM-2: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "unprognostic (1.23e-3)" "unprognostic (8.77e-3)" "unprognostic (2.44e-1)" "unprognostic (3.81e-2)" "unprognostic (6.62e-2)" "unprognostic (1.35e-3)" "unprognostic (1.97e-2)" "unprognostic (2.53e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (6.73e-2)" "unprognostic (6.59e-5)" "unprognostic (1.55e-1)" "unprognostic (8.40e-2)" "unprognostic (7.71e-3)" "unprognostic (4.59e-2)" 0.6 0.3 0.7 0.7 1.5 1.4 0.7 0.4 0.4 0.8 0.2 3.5 0.3 0.2 0.6 2.9 0.3 8.6 1.0 0.3 1.1 1.2 0.3 0.2 1.8 3.7 0.2 0.1 2.2 0.5 9.3 3.6 0.2 10.6 0.5 0.0 38.1 0.5 0.4 0.2 1.1 0.4 0.1 0.7 1.4 0.5 19.3 0.7 0.0 0.6 0.4 0.2 0.2 1.2 0.6 0.4 11.7 0.8 0.3 0.7 0.1 3.0 0.9 1.8 1.8 0.1 0.0 1.7 0.0 0.2 1.0 1.0 1.3 1.7 0.9 0.7 0.0 2.9 0.5 0.6 0.3 0.4 4.7 1.9 0.7 0.7 1.2 0.0 3.2 2.9 0.1 0.0 0.2 0.3 0.6 0.0 0.6 1.6 0.6 0.1 0.4 0.4 1.9 0.8 0.1 0.4 0.6 0.8 0.3 0.1 0.4 1.9 0.9 0.1 0.5 0.1 1.4 1.1 0.3 0.2 0.7 1.1 0.2 1.1 0.5 0.1 0.4 0.5 0.6 1.0 0.5 0.8 0.9 0.4 0.5 0.4 0.2 0.4 0.3 0.4 0.6 0.4 0.7 11.7 0.3 0.8 0.4 0.1 0.1 0.7 1.5 0.4 0.4 1.1 1.2 0.2 0.1 10.6 0.7 0.0 5.4 0.0 2.4 0.3 11.3 0.6 0.0 57.6 7.9 3.5 347.5 0.4 0.0 0.3 112.5 1.1 0.0 0.0 0.2 0.7 0.4 1.2 2.3 0.0 0.2 4.8 0.0 1.3 0.0 27.7 0.6 0.9 1.7 0.0 0.0 15.7 0.1 0.0 0.4 0.0 298.8 0.0 1.0 7.0 6.0 0.4 0.7 0.0 0.0 0.8 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386817-66492312 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 62000 "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 28.6 16.9 33.9 19.1 54.1 29.0 23.6 32.5 48.4 12.5 12.1 8.4 10.2 10.0 11.8 16.5 22.0 10.6 14.4 19.1 49.2 26.4 15.3 53.1 16.4 23.3 17.6 31.2 13.5 11.7 23.4 12.0 15.4 17.2 14.4 12.9 9.1 13.2 12.4 39.5 12.3 10.9 16.9 17.4 14.5 10.8 7.8 12.6 12.6 12.3 9.7 27.9 13.6 18.7 4.6 16.2 5.5 8.2 8.4 7.9 2.7 33.6 15.9 31.9 13.3 19.3 14.5 18.5 24.4 20.9 26.5 23.7 23.8 27.7 30.9 30.3 20.1 20.2 30.0 29.8 35.7 31.3 24.9 17.8 9.9 16.6 12.9 15.6 13.0 14.8 11.2 22.1 19.2 28.5 28.3 20.7 15.8 17.5 39.6 38.7 13.0 10.5 17.1 16.3 31.2 13.9 11.9 19.7 27.5 25.7 14.5 19.7 11.0 19.8 15.5 20.5 26.9 14.0 11.2 28.5 34.6 21.2 24.4 36.2 24.5 43.6 19.7 36.5 23.1 16.1 3.2 8.2 5.5 7.4 8.2 6.7 3.0 6.6 6.9 8.3 4.6 7.9 4.9 3.9 8.4 7.3 16.2 4.9 2.7 33.9 54.1 32.5 46.9 49.2 26.4 17.6 31.2 17.2 12.6 26.8 21.9 30.2 40.5 73.6 8.5 16.9 38.2 6.7 13.6 24.4 13.7 40.9 39.7 65.3 10.2 19.0 20.0 46.7 20.4 39.4 31.3 59.4 9.2 116.5 44.9 9.5 20.8 17.2 91.3 18.3 20.8 67.7 50.6 88.4 17.0 33.9 70.1 21.0 20.5 28.5 5.6 6.5 53.6 16.3 44.5 58.8 43.3 40.5 16.8 65.5 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124129 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease mutation, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Late spermatids: 596.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol NA NA Cytosol "CAB003835: AB_562312, HPA051993: AB_2681685" "unprognostic (4.39e-1)" "prognostic favorable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favorable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favorable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 23.9 33.0 35.6 27.6 36.1 46.7 30.2 31.2 43.4 22.6 38.8 24.6 27.0 70.9 21.8 23.2 32.8 21.7 27.9 41.4 33.1 31.0 22.7 42.0 24.1 44.5 34.4 29.2 30.8 46.0 18.9 29.7 21.3 26.1 25.7 24.3 21.7 41.5 24.0 134.9 27.4 56.7 19.0 25.2 25.9 28.3 42.0 20.9 44.1 26.2 42.2 29.1 20.0 26.9 11.4 10.7 28.3 10.6 11.3 12.1 4.5 36.8 40.7 22.3 31.3 30.9 37.3 22.3 24.3 32.6 33.3 30.2 35.2 20.0 31.6 23.0 27.7 26.8 26.6 17.4 26.0 25.8 26.8 21.2 11.5 22.2 38.9 47.3 21.1 24.3 41.1 25.3 23.4 31.2 44.6 29.4 28.8 22.0 62.4 28.0 46.3 41.8 29.7 25.5 27.2 29.6 32.0 14.7 36.1 29.1 23.7 30.3 30.2 22.3 30.9 75.8 26.9 23.8 36.4 25.9 27.3 23.8 69.8 37.4 62.8 38.0 22.1 42.4 38.2 46.8 15.2 9.1 28.3 11.9 10.6 9.7 8.9 9.7 12.1 10.7 11.4 8.9 11.6 14.4 11.3 8.7 6.0 9.2 4.5 35.6 36.1 31.2 43.4 33.1 31.0 34.4 29.2 26.1 20.9 8.9 38.8 57.0 73.8 31.5 79.0 54.9 17.8 10.7 19.4 38.4 39.3 23.7 124.3 17.7 223.1 33.7 242.0 0.0 38.5 28.5 33.0 88.2 19.6 43.1 46.2 114.4 60.6 34.4 35.6 596.7 33.1 29.7 40.5 12.6 77.6 82.3 41.7 90.9 21.5 75.0 82.4 25.8 32.5 25.9 14.5 55.8 29.7 45.4 69.4 97.8 MAP2K3 "MAPKK3, MEK3, MKK3, PRKMK3" ENSG00000034152 "Mitogen-activated protein kinase kinase 3" P46734 17 21284672-21315240 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018548 Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB018548: AB_631927" "unprognostic (2.31e-1)" "unprognostic (6.39e-2)" "unprognostic (4.63e-2)" "unprognostic (3.68e-1)" "unprognostic (3.54e-3)" "unprognostic (1.60e-1)" "unprognostic (2.97e-2)" "unprognostic (1.35e-2)" "unprognostic (5.25e-3)" "unprognostic (1.88e-2)" "unprognostic (3.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.33e-1)" "unprognostic (6.48e-2)" "unprognostic (1.22e-2)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" 16.1 12.1 5.5 14.8 7.3 66.9 29.0 12.4 8.9 10.2 12.4 6.3 10.3 18.1 7.6 11.1 24.2 11.6 25.1 26.8 5.6 5.3 15.8 37.1 25.5 34.0 7.4 3.9 10.1 26.3 9.6 15.8 26.7 9.5 12.2 9.3 12.7 18.5 9.2 46.4 20.9 23.8 18.1 7.6 26.7 16.3 5.3 4.1 16.4 11.5 45.0 21.4 16.0 17.3 13.2 17.3 49.2 33.3 5.4 16.2 10.0 21.4 21.7 2.9 13.2 17.6 11.3 11.0 33.2 36.1 26.5 24.4 24.1 13.8 19.4 13.6 52.0 22.4 21.3 9.2 29.5 18.9 20.1 16.8 11.2 12.5 21.8 5.5 14.7 23.1 8.7 8.4 36.1 10.9 8.3 11.8 11.4 2.1 9.7 22.1 21.3 7.4 14.0 8.3 38.6 12.5 15.3 18.7 14.3 15.0 22.6 7.9 2.8 12.3 13.3 23.1 30.1 6.6 5.0 10.8 25.2 20.6 26.9 21.4 12.1 6.1 25.0 24.3 12.7 13.0 14.5 16.0 25.2 14.6 24.0 12.6 13.2 12.1 13.6 17.3 10.6 7.8 10.1 49.2 5.4 33.3 12.7 16.2 10.0 5.5 7.3 12.4 8.9 5.6 5.3 7.4 3.9 9.5 4.1 35.7 59.6 38.8 149.8 229.1 5.9 17.0 45.9 29.4 45.5 21.0 3.9 51.1 63.0 81.6 1.1 21.1 72.0 210.2 69.2 75.4 38.0 143.0 94.4 63.8 45.6 17.5 115.4 21.5 64.9 0.7 11.2 56.1 82.7 15.4 50.2 16.4 93.5 56.1 15.6 27.9 6.9 0.0 70.0 0.9 4.4 190.7 56.1 56.1 31.9 222.1 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020824-12143830 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 13.2" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "SuSa: 67.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: AB_2684197" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 10.7 13.2 23.7 9.4 21.0 3.1 14.4 25.0 42.7 12.5 11.5 7.9 8.5 9.6 12.1 17.8 18.5 11.5 10.7 14.9 31.7 29.3 15.8 20.6 11.4 14.6 24.5 27.1 13.0 11.1 19.6 16.7 15.1 23.4 14.5 13.1 6.5 9.8 13.2 20.6 14.4 9.9 13.5 16.3 10.7 10.7 10.3 9.8 10.3 16.5 11.6 13.4 11.1 11.2 2.8 1.8 13.2 4.3 3.5 3.3 2.3 10.6 9.2 12.1 6.2 6.7 8.7 7.7 7.3 9.6 8.3 8.0 5.4 3.7 4.4 5.9 11.3 5.4 7.1 10.5 10.1 12.5 7.8 12.3 4.9 5.4 10.2 7.9 4.7 7.4 7.2 10.0 9.7 10.2 8.6 7.5 6.3 5.2 2.6 10.4 3.9 5.6 4.4 7.0 11.5 4.5 7.0 13.6 3.0 11.4 6.9 2.4 7.2 8.4 4.5 7.0 67.1 5.7 3.4 6.8 4.1 6.3 5.6 8.6 5.1 5.7 3.5 7.7 3.7 5.9 0.6 2.7 2.0 3.0 1.5 2.7 2.8 2.4 2.4 1.8 2.7 2.0 3.3 13.2 3.5 4.3 1.8 2.6 2.3 23.7 21.0 25.0 42.7 31.7 29.3 24.5 27.1 23.4 9.8 8.9 14.2 10.8 26.3 36.9 14.2 21.2 10.2 2.7 21.6 14.0 7.9 10.7 21.6 11.2 6.3 8.7 11.8 0.0 12.4 8.6 12.9 32.3 1.1 16.3 10.2 17.5 11.5 10.4 17.7 5.8 10.9 11.7 11.8 19.0 13.8 10.3 14.7 11.5 12.0 17.7 9.7 12.9 12.0 7.9 8.1 34.4 21.2 9.5 10.6 40.3 MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542709-67807123 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 115.1;Late spermatids: 149.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022094, HPA027347, HPA027755" Supported Approved Nucleoli,Microtubules NA NA "Nucleoli, Microtubules" "CAB022094: , HPA027347: AB_10599290, HPA027755: AB_10600883" "unprognostic (4.54e-2)" "unprognostic (1.87e-2)" "unprognostic (4.16e-2)" "unprognostic (9.06e-2)" "unprognostic (1.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-1)" "unprognostic (2.41e-2)" "unprognostic (2.83e-1)" "unprognostic (1.47e-2)" "unprognostic (5.41e-2)" "prognostic favorable (8.03e-5)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (3.99e-2)" "unprognostic (2.73e-2)" 18.6 22.2 20.3 13.8 30.9 14.6 23.7 25.0 25.4 17.0 19.3 17.2 19.9 14.7 17.4 11.3 13.5 16.2 14.4 18.8 17.1 16.4 14.2 15.5 13.5 27.9 12.6 11.5 29.0 21.0 34.1 14.4 17.7 22.2 15.9 14.8 15.6 15.7 18.5 28.5 18.7 15.0 19.4 17.2 13.0 15.4 20.3 16.2 40.2 16.9 9.2 11.9 17.0 17.9 6.6 10.2 10.3 7.3 11.7 11.2 5.5 5.3 14.2 8.5 10.0 12.6 22.2 6.7 5.4 10.9 10.1 11.1 5.7 9.6 8.8 11.4 8.9 11.0 8.1 14.5 8.6 8.4 12.8 14.5 12.0 10.6 6.1 15.9 7.2 7.5 15.2 11.3 7.3 16.6 22.3 13.3 20.5 10.5 14.8 8.3 6.9 11.8 8.6 12.0 6.2 6.9 11.7 9.9 14.7 6.1 9.8 5.4 8.4 6.0 8.9 21.4 15.4 11.2 14.2 11.0 10.5 6.9 7.2 7.2 21.0 24.6 10.3 14.0 16.6 7.5 10.3 7.3 6.6 7.7 5.6 11.2 6.6 7.3 9.0 10.2 6.2 10.4 9.5 1.7 11.7 6.2 3.9 7.4 5.5 20.3 30.9 25.0 25.4 17.1 16.4 12.6 11.5 22.2 16.2 6.0 4.3 4.2 7.5 6.2 10.0 8.0 2.5 1.4 1.2 5.2 9.8 10.3 6.6 7.7 115.1 7.0 8.8 0.0 7.4 9.1 7.1 4.5 2.3 6.8 8.8 4.8 9.1 9.8 9.2 149.4 11.5 5.3 10.1 2.8 8.4 16.0 6.9 10.5 11.0 6.8 7.2 0.0 5.1 10.4 8.2 7.2 8.2 8.7 9.4 2.7 MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414698-69553861 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 31.9;skeletal muscle: 55.6" "Cell type enhanced" "Detected in many" 7 "Intestinal endocrine cells: 43.8;Muller glia cells: 32.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 9.3;neutrophil: 19.3;plasmacytoid DC: 31.9" "Group enriched" "Detected in all" 9 "dendritic cells: 31.9;granulocytes: 19.3;monocytes: 9.3" "Cell line enhanced" "Detected in many" "A549: 24.4;AN3-CA: 13.3;HUVEC TERT2: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB007744: AB_562318, HPA031134: AB_10603016" "prognostic favorable (2.27e-6)" "unprognostic (2.24e-1)" "unprognostic (8.46e-2)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.61e-3)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (4.09e-3)" "prognostic favorable (7.52e-4)" "unprognostic (3.61e-2)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (9.43e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-2)" 4.5 2.0 3.2 8.6 5.9 10.1 14.0 13.7 7.5 19.8 21.5 6.2 4.7 7.2 4.7 3.1 3.4 3.3 5.1 2.5 3.9 3.5 4.1 8.6 2.6 10.3 5.4 4.1 2.7 8.5 0.0 3.2 1.1 5.3 2.8 22.8 5.3 4.0 4.6 55.6 2.3 7.3 2.3 6.2 5.9 5.4 2.1 5.4 13.7 2.8 4.8 5.1 3.0 2.5 2.3 31.9 19.3 9.3 1.8 2.1 2.6 0.1 24.4 11.0 13.3 4.7 2.6 1.6 0.1 3.6 1.0 1.5 0.7 1.1 0.6 9.0 0.5 0.8 1.2 3.8 0.5 0.3 0.8 2.0 0.1 6.9 6.8 4.7 1.0 1.0 12.1 0.3 0.3 0.0 1.0 17.5 3.3 0.0 1.7 0.0 0.1 12.7 0.5 7.8 0.5 4.5 4.6 1.1 0.3 4.9 3.4 4.9 7.4 1.0 0.9 2.2 6.1 3.4 1.3 3.1 1.3 1.6 1.1 0.4 1.2 1.3 0.3 1.0 1.5 1.0 0.8 9.3 1.6 1.2 1.1 2.1 1.6 1.4 1.5 2.9 2.3 1.6 1.5 19.3 1.8 0.4 31.9 1.9 2.6 3.2 5.9 13.7 7.5 3.9 3.5 5.4 4.1 5.3 5.4 3.0 7.9 4.7 3.2 2.4 4.9 1.4 2.5 6.7 5.7 0.0 2.0 7.5 19.9 1.2 8.5 2.4 17.0 0.0 3.6 5.4 2.8 1.9 1.1 2.0 5.1 3.2 43.8 4.9 8.9 1.9 4.0 7.0 3.3 0.0 22.4 32.9 1.2 8.6 3.5 1.1 3.8 0.0 3.1 0.0 0.2 3.8 0.7 11.5 23.7 2.3 MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "Golgi apparatus" "CAB004262: AB_627925, HPA001633: AB_1079516, HPA064711: AB_2685331" "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (4.24e-2)" "prognostic favorable (8.54e-5)" "unprognostic (1.80e-3)" "unprognostic (2.55e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-2)" "unprognostic (1.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.54e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (1.73e-2)" "prognostic favorable (1.56e-4)" 16.3 14.9 13.5 16.4 16.4 23.8 13.6 28.7 21.5 14.3 15.6 23.2 15.1 19.3 19.1 9.9 13.6 13.1 14.3 15.8 14.6 11.9 12.8 15.9 12.5 15.9 17.2 13.9 18.4 22.3 13.9 17.0 16.4 16.2 14.4 7.9 14.2 23.0 13.4 61.6 21.3 18.7 14.1 12.5 19.4 14.8 21.5 16.5 9.8 13.7 17.3 12.8 15.4 15.2 3.0 2.6 4.8 2.7 3.3 2.5 1.0 12.9 7.4 6.4 10.6 5.2 5.0 12.1 8.5 4.2 5.8 6.0 10.7 7.9 15.4 13.8 4.5 5.7 11.9 5.6 6.5 2.3 12.2 27.8 10.8 9.8 7.9 6.7 10.1 13.8 5.8 8.5 4.6 5.2 7.7 5.2 11.3 15.8 20.3 3.3 6.8 14.3 24.5 11.4 6.9 16.7 14.3 7.0 15.6 5.2 10.8 11.9 11.9 5.8 10.2 11.8 4.0 11.0 11.5 7.8 17.7 10.1 12.4 11.5 29.4 13.6 14.5 8.9 14.9 7.1 0.0 2.7 1.9 2.3 2.5 1.5 2.1 1.9 2.0 1.3 3.0 1.7 2.5 4.8 3.3 1.5 2.6 0.7 1.0 13.5 16.4 28.7 21.5 14.6 11.9 17.2 13.9 16.2 16.5 23.8 21.5 21.9 31.0 34.3 50.6 12.6 22.9 9.4 5.7 19.2 72.6 23.2 11.6 19.1 3.8 18.7 26.2 0.0 16.4 25.3 18.1 32.9 10.4 17.4 16.3 54.0 35.1 19.0 12.4 8.6 26.7 15.7 30.4 16.2 23.6 25.8 19.2 21.0 11.7 14.7 70.3 32.3 26.9 14.2 26.4 37.3 41.2 28.0 24.2 25.2 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815574-56896152 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 27.5;THP-1: 25.7" "Region enriched" "Detected in many" 6 "olfactory region: 22.5" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 6.7 4.9 5.4 14.6 4.8 15.2 14.9 8.0 4.5 7.6 6.7 5.4 7.3 4.3 7.1 9.4 12.7 7.2 5.9 4.3 3.7 3.2 9.5 4.4 8.8 21.4 6.4 3.1 8.4 9.2 6.3 7.9 8.1 4.5 8.3 4.5 12.6 15.4 9.7 3.5 21.8 11.2 4.0 3.8 21.3 5.5 8.5 5.1 11.7 19.2 6.6 18.2 6.0 11.7 6.6 2.8 6.7 7.2 2.7 5.8 2.3 6.6 4.0 6.3 4.2 1.0 0.8 10.6 1.3 1.7 4.0 5.6 18.7 5.0 5.9 0.4 1.5 3.4 3.4 5.2 2.3 5.6 2.0 2.3 3.3 1.8 8.8 2.5 5.2 9.2 1.0 2.5 1.2 2.0 1.1 1.7 2.0 2.8 10.7 1.0 2.9 3.6 7.1 2.9 3.4 0.5 5.7 4.4 20.3 7.0 6.9 2.6 27.5 3.9 4.9 11.2 5.8 13.4 25.7 5.0 0.4 3.4 1.5 2.4 7.8 4.0 11.3 0.6 3.1 6.8 6.7 4.5 1.0 1.2 6.8 1.2 6.6 3.8 1.8 2.8 5.1 2.5 0.9 2.6 2.7 7.2 1.5 5.8 2.3 5.4 4.8 8.0 4.5 3.7 3.2 6.4 3.1 4.5 5.1 6.0 9.8 47.7 14.5 46.5 15.2 2.7 50.9 4.0 12.5 34.9 45.2 12.9 6.6 14.2 1.6 13.5 6.6 0.0 12.8 7.7 11.3 11.9 7.0 12.1 26.3 27.0 9.8 17.2 81.7 1.9 4.9 40.3 35.4 45.9 10.1 10.6 13.0 7.0 1.8 20.1 34.7 6.5 5.2 10.0 15.0 47.8 5.6 16.6 8.9 10.0 MAP3K10 "MEKK10, MLK2, MST" ENSG00000130758 "Mitogen-activated protein kinase kinase kinase 10" Q02779 19 40191744-40215575 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0" "Cell type enhanced" "Detected in many" 7 "Bipolar cells: 13.9;Horizontal cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007039 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Nucleoplasm, Actin filaments, Cytosol" "HPA007039: AB_1079357" "unprognostic (2.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-3)" "unprognostic (2.03e-2)" "unprognostic (2.04e-1)" "prognostic favorable (8.69e-4)" "unprognostic (4.50e-3)" "unprognostic (1.80e-1)" "unprognostic (3.94e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-3)" "unprognostic (4.62e-3)" "unprognostic (6.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-2)" "unprognostic (4.77e-3)" "prognostic favorable (2.13e-4)" 7.7 7.0 29.6 4.7 22.8 3.7 2.2 14.3 32.0 3.3 3.4 5.3 1.8 4.4 4.5 1.8 3.7 3.1 4.0 8.2 28.2 11.2 4.7 2.1 4.2 4.6 11.5 9.4 4.3 8.1 4.7 5.2 3.7 9.0 4.6 2.0 2.4 6.9 4.8 22.9 5.6 5.0 4.0 5.3 6.7 6.2 6.6 7.1 2.3 3.3 2.6 2.4 3.8 5.4 0.8 0.0 0.0 0.2 0.0 0.9 0.0 6.3 7.6 2.4 5.6 2.2 1.3 6.5 4.4 2.2 2.0 2.1 1.7 1.8 5.8 4.6 1.5 5.1 2.1 0.9 2.3 0.3 11.0 7.2 1.5 3.2 1.7 4.2 1.3 3.7 1.2 5.5 2.2 1.5 2.3 1.9 8.2 5.5 9.9 0.6 3.8 4.8 2.3 2.8 2.1 5.0 5.9 2.5 3.4 1.8 4.0 7.9 11.4 5.1 1.9 10.4 1.5 2.5 2.3 3.1 5.4 5.2 7.8 8.5 13.1 7.5 2.6 6.2 2.4 7.8 0.0 0.1 0.0 0.4 0.2 0.0 0.8 0.2 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 29.6 22.8 14.3 28.7 28.2 11.2 11.5 9.4 9.0 7.1 0.0 0.0 2.2 1.5 1.3 13.9 2.4 0.0 0.0 0.0 7.0 7.9 0.6 0.0 2.3 2.6 2.3 2.6 0.0 3.6 0.7 1.9 2.0 0.0 2.6 2.2 22.3 4.1 3.7 2.2 6.5 2.8 1.1 1.7 1.0 1.9 5.2 3.4 1.9 4.6 3.7 7.3 6.5 2.6 2.6 1.7 2.4 1.1 1.9 2.1 1.7 MAP3K11 "MEKK11, MLK3, PTK1, SPRK" ENSG00000173327 "Mitogen-activated protein kinase kinase kinase 11" Q16584 11 65597755-65615382 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 75.8" "Cell type enhanced" "Detected in all" 4 "Enterocytes: 120.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010165 Approved Supported "Centriolar satellite,Cytosol" NA NA "Centriolar satellite, Cytosol" "CAB010165: AB_631936" "unprognostic (8.36e-2)" "unprognostic (1.17e-2)" "unprognostic (1.06e-1)" "unprognostic (9.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.87e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-2)" "unprognostic (4.50e-2)" "unprognostic (4.30e-1)" "unprognostic (4.69e-2)" "unprognostic (2.77e-2)" "unprognostic (3.13e-2)" "unprognostic (2.01e-2)" "unprognostic (7.62e-2)" "unprognostic (1.95e-1)" "unprognostic (8.27e-3)" 23.2 10.8 11.4 23.7 21.2 14.2 27.4 7.9 13.8 8.6 15.8 29.8 6.1 31.9 11.0 8.1 14.7 11.6 12.0 11.6 13.3 8.1 16.1 31.2 21.1 14.4 30.9 8.2 8.4 12.5 8.3 10.3 14.7 16.7 13.4 8.2 15.4 13.5 9.5 11.9 13.7 31.9 8.6 17.7 28.8 16.9 8.6 19.0 8.9 13.6 7.6 12.7 8.9 75.8 2.3 7.6 13.8 12.0 1.8 3.5 5.6 16.7 14.8 8.0 8.5 2.6 3.2 8.2 6.5 4.6 7.8 5.3 14.8 16.3 6.3 24.1 5.1 11.4 14.7 4.8 7.0 2.9 13.9 6.1 17.8 10.1 17.7 7.1 10.2 26.9 5.1 6.8 5.8 5.3 8.3 21.8 7.3 7.7 12.7 4.1 20.8 11.9 19.2 8.8 11.2 19.0 19.8 5.2 12.8 7.4 14.6 7.3 8.2 7.7 22.2 38.1 4.2 17.7 16.6 24.4 12.0 13.0 17.5 11.5 8.1 9.2 5.6 14.0 11.8 27.8 4.3 7.7 9.2 2.4 12.0 2.4 2.0 2.6 3.5 7.6 2.3 2.0 1.5 13.8 1.8 11.7 2.3 1.4 5.6 11.4 21.2 7.9 13.8 13.3 8.1 30.9 8.2 16.7 19.0 20.8 19.7 19.7 21.8 18.7 22.9 9.6 17.8 5.3 6.8 10.4 23.6 21.6 16.6 18.8 9.8 69.5 120.7 23.3 23.8 13.7 11.6 23.2 25.4 45.6 44.4 17.5 40.3 49.7 42.7 44.8 8.9 39.8 20.3 37.9 41.8 14.5 24.8 77.2 6.0 21.1 53.6 32.3 11.2 11.4 13.6 26.2 28.7 21.2 36.5 30.8 MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.3" "Cell type enhanced" "Detected in many" 10 "Cone photoreceptor cells: 35.3;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 3.4;monocytes: 1.7;T-cells: 2.8" "Cell line enhanced" "Detected in many" "ASC diff: 26.4;HHSteC: 25.2;HSkMC: 25.1;hTERT-RPE1: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Nucleoplasm, Plasma membrane" "HPA039936: AB_10795239, HPA071996: AB_2686481" "unprognostic (4.01e-1)" "unprognostic (3.30e-1)" "unprognostic (8.89e-3)" "unprognostic (6.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.97e-2)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "prognostic favorable (1.51e-4)" "unprognostic (8.50e-3)" "prognostic unfavorable (5.43e-10)" "unprognostic (1.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" 8.0 8.7 12.3 5.8 16.0 3.0 5.1 40.3 20.6 14.1 6.1 7.0 7.8 3.6 15.1 5.8 4.6 11.5 16.1 4.2 9.4 7.7 4.5 1.4 8.8 4.5 6.4 14.7 13.7 1.8 3.0 12.7 7.3 10.8 5.9 4.6 9.5 2.4 13.5 1.2 4.5 4.1 16.9 5.3 5.3 3.9 6.5 7.4 2.7 4.3 1.4 3.2 11.3 6.4 0.3 0.6 3.4 1.7 0.6 2.8 0.5 0.2 7.0 4.4 6.8 26.4 14.1 0.5 4.7 8.9 5.2 5.3 0.1 0.8 1.5 2.7 5.1 4.2 0.0 2.0 3.1 2.1 2.3 2.4 1.7 3.6 0.0 25.2 0.0 1.7 25.1 2.3 7.1 3.7 33.3 8.1 3.5 0.0 7.5 4.9 3.0 1.7 0.3 1.5 0.0 2.6 2.4 2.9 0.4 2.6 0.0 4.4 6.0 2.5 3.2 6.7 1.0 2.2 4.4 5.9 5.0 5.4 2.3 1.2 3.0 3.4 0.0 8.1 3.0 4.9 0.0 1.7 0.0 1.5 1.3 2.8 0.3 2.1 2.3 0.6 0.0 0.9 1.2 3.4 0.6 0.4 0.3 0.4 0.5 12.3 16.0 40.3 20.6 9.4 7.7 6.4 14.7 10.8 7.4 6.0 13.4 5.6 1.9 0.7 26.7 0.7 10.2 8.1 11.4 1.8 35.3 1.6 8.3 5.4 1.2 3.7 4.6 0.0 1.6 1.8 3.8 2.7 12.7 7.7 3.6 28.6 3.4 7.4 12.7 1.4 7.5 5.9 0.0 7.2 2.5 17.4 4.5 2.6 7.8 7.0 81.9 6.5 4.9 2.3 1.9 0.9 1.8 7.5 3.5 2.0 MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489097 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "monocytes: 456.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: AB_10670027, HPA036691: AB_10673661, HPA036692: AB_10670845" "unprognostic (8.95e-2)" "unprognostic (6.72e-3)" "unprognostic (9.46e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.61e-1)" "unprognostic (1.23e-2)" "unprognostic (9.04e-2)" "prognostic favorable (1.11e-4)" "prognostic unfavorable (7.27e-5)" "unprognostic (2.70e-3)" "unprognostic (1.54e-2)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (6.64e-2)" "unprognostic (9.31e-3)" 9.8 24.8 21.7 8.7 22.2 9.5 15.1 16.4 26.1 12.9 16.9 18.4 10.5 16.8 12.9 42.1 15.2 14.6 13.1 8.1 19.2 18.6 21.9 20.7 15.2 7.4 23.2 17.1 16.5 24.9 20.9 24.5 9.1 21.8 14.5 18.9 18.6 26.2 11.4 3.3 9.8 23.4 12.1 26.4 8.7 16.4 12.9 15.8 4.4 18.6 8.3 10.3 12.5 11.5 23.7 21.5 21.1 13.2 11.5 17.4 7.8 29.1 5.8 11.3 0.3 10.3 12.7 6.7 6.7 4.6 10.9 13.2 11.2 11.0 0.2 23.0 12.2 18.2 16.7 0.3 15.5 19.4 32.5 15.0 0.1 7.9 9.2 11.2 15.3 8.4 11.5 13.6 9.3 11.7 11.3 12.1 0.3 0.3 23.7 9.7 9.1 1.8 7.2 13.0 22.5 13.7 0.2 13.5 16.0 19.2 7.6 18.6 12.4 11.3 17.1 23.2 12.9 25.8 8.6 8.0 9.0 11.7 16.2 14.5 12.1 15.6 9.6 13.2 7.8 14.7 6.4 13.2 5.1 10.3 12.2 15.8 23.7 12.4 12.8 21.5 19.0 17.4 16.8 21.1 11.5 8.6 9.4 4.8 7.8 21.7 22.2 16.4 26.1 19.2 18.6 23.2 17.1 21.8 15.8 50.6 76.2 44.7 172.9 125.7 111.5 22.1 104.4 64.3 84.2 75.0 86.4 120.9 243.7 92.5 109.7 52.6 82.0 0.0 111.2 29.4 48.3 249.1 28.9 83.1 55.4 42.9 102.2 83.4 50.4 168.4 40.0 59.4 81.0 456.3 109.9 93.7 112.0 96.2 50.9 224.8 81.3 45.3 74.0 119.3 28.8 127.2 170.1 31.2 98.7 249.0 MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263121-45317040 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "monocytes: 49.5" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 22.4;HDLM-2: 23.0;U-251 MG: 22.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: AB_2732436, HPA027270: AB_2732437" "unprognostic (1.05e-2)" "prognostic favorable (5.27e-5)" "unprognostic (2.71e-2)" "unprognostic (9.42e-2)" "unprognostic (5.31e-2)" "unprognostic (2.61e-3)" "unprognostic (2.70e-2)" "unprognostic (1.72e-1)" "unprognostic (3.40e-1)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" 3.7 3.4 3.0 14.7 4.0 3.4 2.7 4.9 3.6 5.0 7.3 4.5 3.5 6.0 5.5 3.3 6.8 4.2 6.2 4.5 3.0 4.4 5.1 4.9 12.0 3.0 0.6 3.5 5.7 3.5 7.7 1.5 4.6 5.2 3.5 4.3 7.5 4.8 14.5 6.1 9.6 5.2 4.1 8.4 4.0 4.5 4.5 7.1 2.2 6.9 18.0 4.9 2.8 9.5 4.8 7.7 3.6 5.6 5.2 2.3 9.5 22.4 2.3 4.0 1.6 3.8 5.7 2.6 1.8 8.5 5.2 3.4 11.9 4.2 13.6 2.8 8.5 6.8 1.0 3.6 4.4 23.0 1.7 0.9 6.1 1.5 4.1 0.7 4.5 5.9 2.3 4.2 2.2 9.0 1.6 2.0 1.8 18.3 4.3 3.5 4.0 1.5 1.2 5.9 3.1 5.2 6.9 9.6 6.2 1.9 2.4 1.9 4.1 2.7 2.9 3.4 1.7 0.4 3.6 3.9 6.0 3.3 22.5 17.5 6.5 2.2 2.2 2.5 5.2 1.5 3.4 1.6 3.5 3.6 2.0 7.6 2.4 2.5 2.3 9.5 2.6 2.5 7.7 5.6 2.2 4.8 5.2 2.3 3.0 13.8 9.7 13.7 0.0 3.6 2.0 15.3 9.4 4.5 0.0 3.9 0.7 0.0 4.2 3.7 1.6 11.2 0.0 2.3 1.2 1.8 6.5 1.1 8.1 4.4 1.6 12.6 4.9 7.8 4.5 4.4 6.2 0.0 49.5 6.4 2.2 3.3 7.8 1.1 2.5 2.7 0.0 0.6 4.5 2.4 0.0 0.0 5.1 6.7 5.0 MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.3;brain: 13.2" "Cell type enhanced" "Detected in some" 12 "Alveolar cells type 2: 1.9;Cardiomyocytes: 2.5;Collecting duct cells: 5.2;Cone photoreceptor cells: 3.9;Distal tubular cells: 3.3" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 6 "pons and medulla: 13.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.2;HAP1: 7.9;HEK 293: 6.7;JURKAT: 3.9;REH: 4.1;SuSa: 8.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA004006 Approved Vesicles NA NA Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" 0.1 17.3 0.5 0.4 0.3 0.5 0.1 2.3 0.1 0.1 0.1 5.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.5 3.6 0.1 0.5 0.0 0.1 0.0 1.3 4.1 0.4 5.7 0.0 13.2 0.1 0.0 4.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 2.6 0.1 2.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.4 0.0 7.9 0.0 0.0 1.3 6.7 2.7 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.5 0.0 0.0 0.2 0.0 2.1 2.0 0.0 0.8 4.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 2.3 0.1 0.4 0.5 0.1 0.0 13.2 0.0 0.0 1.9 0.0 0.6 0.1 0.6 2.5 0.0 0.0 0.0 5.2 3.9 0.0 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.1 0.0 0.6 0.0 0.0 0.2 1.2 0.0 0.1 0.0 0.0 0.0 MAP3K19 "FLJ23074, RCK, YSK4" ENSG00000176601 "Mitogen-activated protein kinase kinase kinase 19" Q56UN5 2 134964491-135047468 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.3;fallopian tube: 23.9" "Group enriched" "Detected in some" 5 "Ciliated cells: 151.3;Early spermatids: 55.2;Late spermatids: 74.5" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.8" "Region enhanced" "Detected in many" "pons and medulla: 18.3" "Cell type enriched" "Detected in single" 6 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 6 "dendritic cells: 1.5" "Group enriched" "Detected in some" 4 "RPMI-8226: 4.1;U-266/70: 2.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 20.2" HPA011388 Uncertain Cytosol NA NA Cytosol "HPA011388: AB_1848822" "unprognostic (7.12e-3)" "unprognostic (6.55e-3)" "unprognostic (6.96e-2)" "unprognostic (3.90e-3)" "unprognostic (3.63e-1)" "unprognostic (2.21e-1)" "unprognostic (1.96e-1)" "unprognostic (9.38e-2)" "unprognostic (1.09e-1)" "unprognostic (4.33e-1)" "unprognostic (2.02e-2)" "unprognostic (1.32e-1)" "unprognostic (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.13e-2)" "unprognostic (1.54e-1)" "unprognostic (2.83e-4)" 0.1 0.2 1.7 0.2 6.2 0.1 0.1 0.0 0.5 1.1 0.2 7.3 0.0 0.2 1.0 6.7 0.2 23.9 0.1 0.1 2.9 3.8 0.2 0.2 5.6 0.2 0.5 1.5 7.3 0.1 0.1 1.0 0.1 18.3 0.3 0.2 0.0 0.2 0.2 0.3 0.2 0.2 0.1 0.5 0.2 0.2 7.6 3.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 4.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 1.7 6.2 0.0 0.5 2.9 3.8 0.5 1.5 18.3 3.1 0.0 0.6 0.0 0.0 0.0 0.2 0.4 0.0 151.3 17.0 0.0 9.8 0.0 0.0 0.0 55.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 74.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 1.1 0.0 0.0 0.0 0.0 0.1 MAP3K2 "MEKK2, MEKK2B" ENSG00000169967 "Mitogen-activated protein kinase kinase kinase 2" Q9Y2U5 2 127298730-127388465 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 13.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021540 Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA021540: AB_2670742" "unprognostic (5.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.58e-1)" "unprognostic (9.46e-2)" "unprognostic (1.02e-1)" "unprognostic (5.76e-2)" "unprognostic (7.19e-2)" "unprognostic (4.50e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.97e-3)" "unprognostic (7.56e-2)" "unprognostic (8.93e-2)" "unprognostic (8.88e-2)" "unprognostic (2.11e-1)" 18.5 14.5 13.7 20.1 14.5 41.0 22.6 20.1 16.3 16.6 19.6 12.7 18.9 18.8 19.8 18.0 13.4 15.9 18.6 13.3 12.5 10.2 15.5 27.6 20.0 28.5 17.9 13.0 20.3 15.4 23.8 21.2 13.9 12.3 13.6 13.1 12.2 18.1 25.5 24.5 19.4 22.5 18.1 14.9 17.0 18.0 14.9 14.3 25.8 22.5 13.7 16.8 17.1 20.3 3.1 5.1 13.6 2.9 2.3 2.1 1.1 16.4 7.0 5.6 5.7 7.9 10.5 9.4 10.3 11.2 10.2 8.3 8.4 7.3 10.9 17.8 14.7 9.4 14.0 9.0 6.9 11.5 27.3 7.0 10.1 12.8 7.3 9.2 10.1 21.9 9.4 7.6 12.3 15.2 9.0 4.7 8.2 4.7 21.8 10.0 6.0 11.9 7.2 5.8 4.6 9.2 7.8 10.6 8.1 4.1 15.5 11.2 6.0 15.0 9.2 9.3 4.8 6.0 7.8 10.7 20.0 18.8 9.2 13.9 22.7 16.3 11.2 9.6 6.7 8.6 4.0 2.9 2.0 1.7 1.8 2.1 3.1 1.6 1.7 2.4 2.6 1.9 2.0 13.6 2.3 2.2 5.1 1.4 1.1 13.7 14.5 20.1 16.3 12.5 10.2 17.9 13.0 12.3 14.3 77.4 39.5 24.5 32.1 64.0 51.3 27.5 38.2 57.6 46.6 27.9 100.1 16.2 11.6 17.3 3.2 38.8 49.0 23.3 29.5 16.3 51.8 41.5 60.0 61.1 46.1 68.3 43.6 22.1 61.3 3.8 39.1 76.0 54.0 23.4 36.2 25.5 35.7 24.6 48.8 27.2 56.9 19.4 48.6 31.4 55.2 68.6 22.0 30.5 24.4 35.7 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268010 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 96.1" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 1: 35.7;Alveolar cells type 2: 51.9;Cytotrophoblasts: 48.5;Ductal cells: 34.2;Pancreatic endocrine cells: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "myeloid DC: 13.7" "Group enriched" "Detected in many" 5 "dendritic cells: 13.7;monocytes: 8.0" "Cell line enhanced" "Detected in many" "hTERT-HME1: 44.9;U-138 MG: 48.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA NA Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 21.7 5.0 2.9 7.4 3.3 0.8 9.2 2.8 3.1 25.7 24.8 2.1 10.7 3.1 30.2 15.4 26.2 13.1 14.9 52.5 3.5 3.0 2.4 8.5 7.5 2.5 4.5 3.0 21.7 4.4 22.6 3.1 6.9 4.2 25.6 5.4 11.5 6.7 15.8 96.1 5.8 8.0 68.4 4.7 3.7 15.8 6.6 3.5 2.8 6.7 38.0 4.9 46.7 24.0 2.1 13.7 2.3 8.0 0.4 1.6 2.7 8.9 7.5 5.9 7.8 17.3 25.8 3.7 32.3 25.3 15.1 16.3 5.1 5.9 6.9 8.5 32.3 13.3 6.1 8.8 17.1 34.1 13.4 5.9 11.2 8.5 1.0 6.9 10.0 11.9 20.7 7.4 28.4 44.9 12.6 10.0 7.6 5.0 1.3 9.9 3.8 6.3 5.0 3.3 7.5 4.3 9.3 12.1 0.0 3.7 5.1 3.5 3.4 12.4 3.0 5.3 10.1 3.4 5.4 10.0 48.3 19.8 14.3 7.3 0.0 0.0 1.4 34.7 2.7 5.0 0.1 8.0 0.0 0.9 7.5 0.9 1.5 0.8 1.6 13.7 2.1 0.0 0.8 2.3 0.4 6.6 0.3 0.7 2.7 2.9 3.3 2.8 3.1 3.5 3.0 4.5 3.0 4.2 3.5 35.7 51.9 0.0 0.0 0.0 0.0 0.0 0.0 24.1 13.6 10.4 0.0 48.5 1.7 34.2 0.0 0.0 0.0 0.0 23.2 22.4 0.0 0.0 4.7 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 27.1 0.0 0.0 31.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.0 0.0 0.0 MAP3K21 "KIAA1804, MLK4" ENSG00000143674 "Mitogen-activated protein kinase kinase kinase 21" Q5TCX8 1 233327768-233385148 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.9" "Cell type enhanced" "Detected in some" 18 "Alveolar cells type 1: 32.8;Alveolar cells type 2: 7.7;Collecting duct cells: 14.0;Ductal cells: 9.7;Exocrine glandular cells: 8.4;Pancreatic endocrine cells: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 6 "NK-cell: 5.0" "Lineage enriched" "Detected in single" 6 "NK-cells: 5.0" "Cell line enhanced" "Detected in many" "HEK 293: 18.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007636 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA007636: AB_1079392" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-3)" "unprognostic (4.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (8.21e-2)" "unprognostic (3.76e-2)" "unprognostic (2.23e-1)" "unprognostic (1.71e-1)" "unprognostic (9.22e-2)" "unprognostic (4.84e-2)" 0.6 3.2 2.0 3.4 2.2 1.3 2.2 10.0 3.3 1.5 11.4 0.6 9.1 9.9 0.8 5.2 2.4 3.9 3.9 0.7 1.3 2.1 12.5 13.3 5.6 0.5 0.9 1.7 0.8 28.9 4.4 2.6 1.0 1.2 1.3 6.0 1.0 3.7 2.5 0.4 2.7 17.2 0.3 0.9 0.7 10.1 12.4 0.6 0.5 2.4 0.8 1.3 1.1 1.6 0.5 0.8 0.1 0.3 5.0 0.2 0.1 7.4 12.7 0.2 0.0 0.0 0.0 6.4 0.2 0.0 0.3 0.5 7.0 6.5 0.7 5.2 0.1 2.4 4.0 9.5 3.9 0.8 13.8 18.3 0.1 7.1 0.0 0.5 12.1 2.9 0.1 5.2 0.2 7.4 1.4 0.4 5.8 0.1 2.4 0.0 1.6 3.8 4.3 9.1 8.7 5.6 0.0 0.0 13.3 8.8 3.1 9.4 2.5 4.3 0.2 0.0 1.0 3.7 3.9 0.0 0.0 1.2 0.0 7.4 2.3 2.9 0.0 1.2 3.3 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.8 0.5 0.0 0.0 0.1 5.0 0.0 0.2 0.2 0.1 2.0 2.2 10.0 3.3 1.3 2.1 0.9 1.7 1.2 0.6 32.8 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 14.0 0.0 0.0 3.3 9.7 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 7.8 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696303 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411" Uncertain Approved Nucleoplasm NA NA Nucleoplasm "CAB007764: AB_562314, HPA035410: AB_2674614, HPA035411: AB_2674615" "unprognostic (9.65e-3)" "unprognostic (1.33e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.46e-3)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" 23.9 11.8 10.5 20.5 15.0 24.8 19.1 26.8 14.9 22.2 21.8 15.0 14.0 8.0 24.5 13.2 16.6 18.3 20.6 37.4 11.3 8.4 17.1 12.4 23.1 21.4 14.4 9.6 21.6 11.4 16.9 12.3 21.0 11.9 18.4 8.3 21.7 12.8 18.5 19.6 15.4 14.7 20.4 13.2 30.4 16.4 26.5 12.3 12.9 15.5 12.8 15.4 19.0 26.8 1.9 3.5 18.3 8.5 1.1 2.6 2.3 10.2 7.7 9.8 9.6 18.9 15.2 4.5 10.2 11.2 12.7 10.3 3.5 2.1 11.1 7.2 19.9 9.3 3.8 6.4 7.2 8.1 9.7 14.1 9.0 10.5 5.0 9.9 6.9 9.7 10.9 5.0 15.8 8.3 8.1 30.8 8.2 5.5 14.7 10.1 7.3 12.4 7.3 6.1 2.1 8.3 6.6 25.2 7.2 4.6 4.7 5.0 12.1 6.9 8.3 8.5 12.9 8.3 6.9 27.7 32.5 8.6 17.6 12.3 14.7 14.8 4.1 7.0 5.6 8.4 8.8 8.5 10.4 2.2 8.3 2.3 1.5 2.6 2.1 3.5 1.9 2.5 2.5 18.3 1.1 8.2 1.3 1.9 2.3 10.5 15.0 26.8 14.9 11.3 8.4 14.4 9.6 11.9 12.3 17.9 12.6 8.8 5.9 6.9 13.9 9.9 2.5 4.0 5.7 15.7 13.7 2.7 8.3 3.7 7.1 33.7 2.1 0.0 6.9 2.9 7.4 8.9 3.5 8.3 13.8 17.5 4.1 39.3 38.3 4.4 13.8 15.3 21.9 8.2 3.3 7.5 4.9 0.0 12.4 2.1 15.0 19.4 11.4 18.0 6.1 9.8 1.1 8.7 4.4 3.7 MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol NA NA Cytosol "HPA007625: AB_1853770" "unprognostic (3.05e-3)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (7.65e-2)" "unprognostic (1.35e-3)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (6.84e-2)" 12.0 8.0 13.1 17.7 12.6 9.1 14.6 23.1 14.0 16.4 13.9 9.3 12.2 9.5 22.2 11.9 21.4 14.1 11.4 12.4 11.9 7.8 9.4 8.2 15.9 14.4 12.8 8.9 17.4 12.1 15.8 16.2 12.4 9.2 14.2 9.8 9.4 15.0 15.4 24.4 15.1 13.3 13.9 7.7 10.6 11.1 13.5 12.4 16.2 10.6 13.0 16.8 15.8 23.9 8.8 5.4 17.5 3.8 3.5 8.9 2.2 4.7 5.4 10.3 8.8 6.4 7.5 6.7 5.4 4.8 6.2 6.6 7.7 3.5 9.8 3.9 13.7 8.9 11.9 10.5 10.8 7.6 7.1 8.6 12.8 5.0 7.5 4.9 13.2 6.2 4.7 12.6 6.5 5.9 9.7 8.1 7.4 32.2 11.3 6.6 4.9 8.9 6.7 6.3 3.4 8.3 9.8 9.5 7.8 5.7 3.5 5.9 5.3 10.1 10.8 0.9 9.4 4.4 16.2 7.5 7.6 9.8 7.1 25.5 6.6 5.3 9.0 9.0 13.7 8.0 17.5 3.8 2.3 5.0 3.0 8.9 6.2 7.1 4.5 4.3 8.8 5.0 4.9 0.2 3.5 1.7 5.4 4.8 2.2 13.1 12.6 23.1 14.0 11.9 7.8 12.8 8.9 9.2 12.4 17.9 12.6 14.2 8.2 8.8 15.7 17.9 10.2 8.1 19.4 14.0 21.6 16.7 3.3 8.0 2.6 11.3 5.9 0.0 6.5 9.4 7.8 10.8 3.5 7.3 6.4 22.3 14.8 4.3 7.0 2.5 10.6 9.0 0.0 18.0 9.4 18.9 9.7 7.0 11.7 5.9 28.6 6.5 8.0 13.5 29.6 10.3 27.7 12.1 10.9 12.9 MAP3K5 "ASK1, MAPKKK5, MEKK5" ENSG00000197442 "Mitogen-activated protein kinase kinase kinase 5" Q99683 6 136557047-136792518 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 55.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007824, HPA063245" Supported Supported Cytosol NA NA Cytosol "CAB007824: AB_598175, HPA063245: AB_2684969" "unprognostic (1.37e-1)" "unprognostic (3.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.38e-1)" "unprognostic (3.19e-1)" "prognostic favorable (6.08e-4)" "unprognostic (8.76e-2)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.91e-4)" "unprognostic (3.97e-1)" "unprognostic (3.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.72e-1)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 7.7 55.6 13.0 7.5 17.6 7.6 5.5 12.9 12.7 4.0 5.4 6.9 3.6 4.6 7.2 5.1 6.4 6.1 4.9 7.3 11.8 6.8 6.8 5.5 7.7 8.8 8.2 6.4 32.4 28.2 1.5 9.9 3.4 7.9 11.6 6.2 5.8 4.2 4.9 3.7 5.0 4.6 4.3 7.5 9.8 8.7 7.3 8.6 2.0 10.0 3.4 9.0 10.8 18.9 2.5 2.5 8.5 3.0 4.1 7.0 1.4 2.9 1.8 0.0 0.0 4.2 11.3 1.0 4.2 22.7 2.2 2.1 0.1 3.0 1.7 6.2 5.8 1.6 4.0 7.2 2.1 5.7 2.3 5.7 15.0 4.0 0.0 20.1 6.9 0.0 14.8 2.8 3.4 9.8 8.4 7.3 2.1 3.7 16.8 15.3 5.6 0.1 5.9 0.7 5.7 2.4 3.9 4.8 6.8 8.8 18.6 5.3 3.5 3.5 3.4 0.9 0.8 0.7 6.2 6.3 3.6 1.1 0.2 3.9 13.7 9.1 0.0 2.8 9.8 3.2 5.7 3.0 3.3 2.7 2.3 4.9 2.0 4.3 3.7 2.5 2.5 0.4 1.4 8.5 4.1 2.1 2.4 7.0 1.4 13.0 17.6 12.9 9.4 11.8 6.8 8.2 6.4 7.9 8.6 6.0 22.4 10.4 17.9 4.4 17.5 21.8 2.5 16.0 34.2 10.4 5.9 0.7 3.3 2.1 4.9 3.8 7.7 0.0 19.7 0.9 5.1 22.3 5.7 9.6 7.1 0.0 33.5 9.8 22.1 2.3 21.9 18.4 0.0 1.0 12.1 42.4 18.9 5.8 13.4 6.8 2.5 12.9 8.0 1.4 15.0 8.8 2.3 6.9 10.0 19.3 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27355184-27366892 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.9" "Cell type enhanced" "Detected in many" 4 "Ito cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: AB_2681380" "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.13e-4)" "prognostic favorable (7.26e-4)" "prognostic unfavorable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 37.5 6.3 7.4 6.9 8.6 1.3 22.1 12.6 8.3 19.9 9.0 2.7 8.9 3.3 13.1 10.3 25.7 12.8 12.4 14.9 6.2 2.6 13.6 5.0 21.7 5.5 11.4 1.9 11.7 8.3 8.2 15.8 7.3 9.8 13.9 5.9 15.7 11.5 9.7 6.3 63.9 6.2 16.0 11.7 8.7 9.0 6.7 7.0 0.6 12.0 16.1 14.3 14.3 18.3 2.7 3.3 5.1 6.9 1.1 7.6 2.4 7.5 7.0 6.3 7.0 8.8 15.4 1.6 9.4 5.4 7.1 5.4 2.1 10.2 0.1 8.4 14.2 2.8 11.9 2.1 6.5 3.6 6.2 5.2 0.5 16.2 3.1 2.7 0.5 0.6 12.4 16.1 7.4 2.6 7.9 4.8 0.5 2.3 4.1 11.3 18.7 0.3 8.6 2.0 7.5 5.8 2.7 4.2 1.7 10.6 7.9 2.3 3.5 9.9 8.7 7.4 2.7 4.6 6.4 9.9 17.9 7.5 19.9 4.9 3.4 4.2 0.1 15.8 6.1 5.2 1.8 1.5 5.1 5.3 3.3 7.6 2.7 5.5 5.9 3.3 2.3 4.4 3.6 2.4 1.1 6.9 0.0 5.6 2.4 7.4 8.6 12.6 8.3 6.2 2.6 11.4 1.9 9.8 7.0 17.9 16.2 4.7 10.4 11.1 0.5 8.9 10.2 1.4 11.4 3.5 0.0 0.9 3.3 2.3 0.4 15.8 1.7 0.0 3.8 1.7 7.7 7.3 2.3 0.8 2.5 4.8 0.0 28.8 12.5 1.1 15.0 5.1 5.0 13.6 4.9 5.2 8.9 0.0 14.2 1.5 0.4 6.5 10.5 8.7 2.1 12.9 0.1 10.2 4.3 14.4 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587045 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 15.5 17.6 19.6 17.3 26.3 10.3 21.6 27.5 27.3 21.1 16.4 15.7 15.8 12.5 23.1 23.6 15.2 15.5 17.6 22.2 20.5 17.5 15.9 15.5 20.0 22.2 22.9 16.4 25.0 13.5 25.8 25.6 23.6 20.7 21.2 15.3 12.4 17.0 23.3 24.3 18.7 14.7 19.4 23.0 23.3 14.7 13.8 21.7 28.2 20.3 10.8 21.9 17.2 18.9 14.2 15.9 19.4 17.7 18.2 22.1 13.6 7.9 7.0 20.5 17.6 15.0 20.1 14.5 16.0 18.5 14.4 18.2 9.0 7.6 17.7 10.2 17.2 12.8 8.5 12.9 12.4 24.6 9.0 13.7 15.8 9.7 11.9 15.8 17.5 12.2 16.6 15.3 14.0 17.2 16.6 13.5 15.6 31.5 14.5 20.6 9.7 8.1 14.8 16.8 12.4 8.9 14.0 36.9 8.6 12.1 8.9 10.4 14.8 11.1 7.7 12.0 16.8 7.7 31.1 12.9 11.7 7.4 10.7 14.8 12.9 11.5 7.7 18.0 19.2 17.2 15.5 12.7 19.4 15.1 17.4 16.8 14.2 14.5 14.4 15.9 10.5 16.5 16.0 12.5 18.2 17.7 9.8 22.1 13.6 19.6 26.3 27.5 27.3 20.5 17.5 22.9 16.4 20.7 21.7 14.9 24.0 20.7 17.4 32.3 22.8 28.8 12.7 16.0 10.3 15.7 25.5 27.6 6.6 16.6 2.6 20.3 9.3 0.0 18.3 26.6 23.5 24.4 12.8 17.9 21.1 27.0 11.6 30.7 26.3 2.2 24.7 25.3 20.3 27.9 15.6 18.9 15.5 7.0 38.5 13.1 21.1 19.4 19.1 24.6 24.0 32.5 40.5 25.5 15.1 23.0 MAP3K8 "c-COT, COT, EST, ESTF, MEKK8, Tpl-2" ENSG00000107968 "Mitogen-activated protein kinase kinase kinase 8" P41279 10 30433937-30461833 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 104.6" "Cell type enhanced" "Detected in many" 5 "Syncytiotrophoblasts: 133.3;Urothelial cells: 168.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005120, HPA017962" Supported Supported Cytosol NA NA Cytosol "CAB005120: AB_2140669, HPA017962: AB_1853776" "unprognostic (1.91e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-1)" "unprognostic (9.29e-2)" "unprognostic (6.73e-2)" "unprognostic (1.00e-2)" "unprognostic (1.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.41e-2)" "unprognostic (8.04e-3)" "unprognostic (8.23e-2)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.76e-7)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.63e-2)" "unprognostic (5.98e-3)" 28.0 7.6 3.6 15.6 4.1 104.6 26.1 1.5 2.6 8.2 8.4 2.7 11.3 3.4 11.5 16.5 13.8 19.5 15.3 20.1 4.3 2.9 6.3 7.6 29.0 33.7 4.3 2.0 9.8 3.6 2.8 4.1 27.5 8.3 7.9 6.8 9.4 6.1 18.4 8.6 15.3 9.6 23.4 9.7 25.6 10.7 6.7 3.6 2.4 7.0 13.2 17.2 13.2 15.6 19.6 13.8 23.7 16.8 12.4 7.8 4.0 8.0 7.2 2.0 4.2 10.5 8.8 9.3 2.0 12.1 4.5 5.4 5.0 18.8 5.3 5.2 4.3 4.4 15.2 4.5 1.9 1.6 12.3 2.3 9.9 12.3 16.0 8.9 3.1 24.4 11.0 1.1 4.5 0.9 4.5 2.0 0.1 4.4 8.0 0.7 4.6 0.1 11.8 0.7 4.3 2.6 0.6 1.6 3.0 4.4 16.4 0.2 0.8 7.2 6.2 0.9 5.7 2.1 6.6 0.1 2.8 2.4 9.9 0.3 12.1 11.3 1.6 4.0 13.4 0.1 17.9 7.0 23.7 7.8 12.0 4.3 9.6 1.7 4.9 6.6 19.6 0.1 3.0 16.7 12.4 16.8 13.8 0.4 4.0 3.6 4.1 1.5 2.6 4.3 2.9 4.3 2.0 8.3 3.6 35.7 41.7 14.7 46.9 103.8 13.9 7.1 5.1 25.4 13.6 3.5 0.0 23.9 1.7 25.2 0.4 36.9 5.2 0.0 9.8 71.1 77.1 32.5 71.4 3.0 109.0 0.0 11.5 14.1 86.6 0.0 7.8 94.5 40.5 78.5 5.3 5.0 17.6 17.5 3.9 2.4 1.1 6.5 75.4 0.0 0.7 74.2 133.3 52.3 5.8 168.4 MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in many" 5 "Horizontal cells: 28.6;Urothelial cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 18.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" 0.5 2.2 5.8 2.0 9.2 1.4 2.8 20.1 16.5 2.4 3.1 1.8 0.4 3.0 1.1 3.4 10.1 2.2 1.5 1.2 5.7 7.1 3.1 2.4 3.9 2.6 5.9 5.9 1.4 4.3 6.8 4.7 2.8 12.8 2.0 3.1 3.1 3.2 1.3 1.9 7.8 2.9 0.7 1.6 1.9 3.4 10.1 1.8 0.6 5.3 3.2 6.8 2.0 3.9 2.3 0.5 1.3 0.2 1.1 1.4 0.3 18.1 8.4 1.6 2.0 0.0 0.0 5.6 0.4 0.2 1.7 1.6 6.0 7.0 3.7 2.5 0.1 3.7 8.6 5.3 10.2 1.9 2.4 1.5 0.2 2.9 4.0 0.3 0.4 0.8 0.1 5.6 1.2 10.6 3.1 0.0 3.3 1.3 0.8 0.4 7.3 2.8 0.4 3.5 7.2 3.9 1.0 3.2 0.7 3.9 8.3 11.6 2.5 5.2 6.2 1.0 3.2 5.6 0.6 0.0 0.0 7.4 0.0 2.8 1.9 4.4 1.9 2.8 0.3 1.1 0.5 0.2 0.8 0.6 0.1 0.1 1.0 0.6 1.0 0.0 2.3 1.0 0.7 1.3 1.1 0.2 0.5 1.4 0.3 5.8 9.2 20.1 16.5 5.7 7.1 5.9 5.9 12.8 1.8 6.0 14.9 0.9 10.9 7.7 15.8 1.8 15.3 0.0 10.3 7.0 11.8 2.5 1.7 5.5 13.2 0.7 3.1 0.0 4.0 1.3 0.8 9.0 1.1 4.9 1.0 28.6 8.1 0.6 0.8 15.9 0.6 1.4 3.3 0.0 3.4 3.4 7.4 3.5 0.0 1.9 12.3 0.0 1.0 5.4 8.5 8.0 3.3 2.9 5.0 25.4 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.2;intestine: 16.9;lymphoid tissue: 39.2" "Cell type enhanced" "Detected in many" 14 "B-cells: 29.0;Rod photoreceptor cells: 58.2;T-cells: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 20.8;HDLM-2: 20.6;Karpas-707: 21.4;REH: 11.4;RPMI-8226: 12.9;U-266/70: 16.9;U-266/84: 16.6;U-698: 26.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 1.6 0.9 1.2 31.4 2.3 6.3 1.1 1.0 1.2 1.0 3.1 1.7 0.1 2.1 0.9 1.4 2.6 1.2 2.9 0.9 1.1 1.4 2.2 1.6 3.9 23.0 2.3 0.7 0.8 1.2 0.2 1.2 1.4 2.1 1.6 1.9 2.0 4.4 0.8 0.5 1.2 16.9 0.7 3.4 34.4 2.3 0.9 1.3 19.1 1.9 1.4 39.2 3.1 1.3 16.2 15.9 1.3 6.2 3.7 14.6 7.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.1 4.4 0.0 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.1 21.4 0.0 0.1 4.9 5.2 0.6 0.1 0.0 11.4 0.0 12.9 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 4.7 0.0 0.0 0.1 0.0 0.0 16.9 16.6 26.2 0.0 5.9 0.0 1.3 3.2 1.2 13.4 6.2 12.4 16.2 11.2 14.0 15.9 10.7 6.2 8.7 0.3 3.7 3.4 14.0 14.6 7.3 1.2 2.3 1.0 1.2 1.1 1.4 2.3 0.7 2.1 1.3 3.0 8.2 29.0 0.1 2.1 6.1 0.6 0.0 0.0 1.2 0.0 11.8 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.2 1.0 0.3 15.1 0.0 2.5 1.6 0.0 1.3 7.1 0.0 0.0 11.7 3.3 2.8 0.0 6.7 0.0 0.0 0.0 0.2 58.2 0.0 0.4 0.6 4.3 0.9 0.1 33.2 0.2 0.1 MAP4K2 "BL44, GCK, RAB8IP" ENSG00000168067 "Mitogen-activated protein kinase kinase kinase kinase 2" Q12851 11 64784914-64803241 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Early spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007330 Enhanced Approved Vesicles NA NA Vesicles "HPA007330: AB_1079361" "unprognostic (1.66e-1)" "unprognostic (2.83e-1)" "unprognostic (3.07e-3)" "unprognostic (4.37e-3)" "unprognostic (2.67e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (4.51e-2)" "unprognostic (3.65e-1)" "unprognostic (5.28e-2)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" 6.9 6.2 9.4 15.2 10.0 19.1 5.8 12.1 15.6 5.2 5.8 10.1 6.9 4.9 6.2 4.0 4.3 4.4 6.3 5.5 9.4 9.2 6.2 3.1 12.0 22.3 8.3 7.3 4.2 7.2 5.2 8.0 12.3 12.5 6.1 4.7 6.7 9.0 8.9 3.4 5.0 9.9 5.6 6.7 22.6 7.1 5.5 6.6 11.5 8.7 3.9 18.8 6.1 5.1 10.8 5.0 8.2 14.8 2.3 9.6 7.1 6.0 5.5 3.6 6.4 3.2 2.0 8.5 4.5 4.3 5.5 3.9 2.4 2.8 10.5 8.4 5.2 9.7 1.8 4.3 4.4 3.3 13.7 2.1 18.5 7.6 5.0 3.9 9.7 7.0 1.9 2.2 4.3 2.7 3.8 13.4 18.4 1.5 1.0 1.6 7.5 5.7 9.7 2.4 3.6 7.4 12.0 0.4 12.1 3.1 3.0 4.3 6.2 3.9 5.1 4.0 4.3 10.3 15.0 10.3 4.6 10.3 4.2 1.9 1.2 2.3 11.4 4.1 14.7 3.4 2.2 4.2 5.6 5.2 12.2 5.3 10.8 7.0 4.7 4.4 7.6 8.6 6.3 8.2 2.3 14.8 5.0 9.6 7.1 9.4 10.0 12.1 15.6 9.4 9.2 8.3 7.3 12.5 6.6 3.0 4.5 18.1 3.3 1.1 19.5 3.6 2.5 1.4 2.3 1.8 23.6 6.4 3.3 1.3 29.3 15.5 1.8 0.0 1.5 10.2 2.8 2.6 1.1 1.8 9.1 11.1 5.8 20.3 8.5 25.2 3.7 8.3 1.7 8.2 2.0 7.0 0.9 11.5 6.7 2.8 13.8 6.5 2.5 1.8 11.1 1.3 4.2 10.0 1.9 1.6 MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437312 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Late spermatids: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 41.6;RT4: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Centriolar satellite" Nucleoplasm "HPA030380: AB_10601132" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (5.87e-3)" "unprognostic (7.34e-3)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.66e-1)" "unprognostic (6.73e-2)" "unprognostic (4.33e-3)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (5.08e-2)" 19.7 18.9 17.6 15.4 17.6 9.6 17.8 37.1 19.6 19.2 16.9 14.6 9.8 13.7 23.5 14.8 11.1 15.3 18.7 19.5 15.4 12.5 26.2 15.4 15.6 5.8 15.4 13.4 24.6 14.0 25.7 24.6 30.8 14.4 18.6 14.1 17.9 13.3 15.7 33.0 17.8 17.2 18.6 15.3 11.5 26.1 21.0 16.5 9.4 25.9 11.3 7.5 18.8 32.6 0.7 0.5 2.5 1.9 1.0 1.3 0.4 9.9 6.2 41.6 6.6 6.8 13.6 11.4 8.8 11.3 8.8 7.5 5.2 5.0 2.1 10.0 6.0 9.1 5.4 15.6 7.8 13.4 2.4 6.4 3.6 4.4 12.1 17.7 1.6 5.9 12.2 7.8 11.4 12.4 9.3 7.5 2.0 4.6 4.1 11.7 5.4 3.4 2.3 12.5 9.4 9.4 3.8 13.5 1.6 11.6 38.5 7.4 8.5 5.2 8.3 23.0 13.7 5.6 2.2 6.1 6.8 8.1 6.1 4.7 6.2 3.5 0.7 8.4 2.6 7.9 2.5 0.7 0.0 1.2 1.1 0.1 0.1 1.2 0.9 0.1 0.7 1.1 1.3 0.0 1.0 1.9 0.5 0.6 0.4 17.6 17.6 37.1 19.6 15.4 12.5 15.4 13.4 14.4 16.5 3.0 6.7 5.1 15.6 15.7 23.8 32.7 17.8 13.4 15.9 21.0 23.6 9.2 16.6 9.0 38.6 10.3 11.9 0.0 10.7 5.5 15.6 20.0 2.3 16.2 9.1 6.4 9.2 15.4 9.5 80.0 19.2 12.2 5.0 1.8 12.5 15.2 12.8 7.0 16.6 10.9 41.2 19.4 12.7 19.5 20.8 16.8 8.7 4.4 9.3 29.0 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 81.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain NA NA "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavorable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 27.0 5.0 68.3 21.1 56.3 32.1 35.2 14.5 50.4 13.2 7.8 47.5 2.1 5.4 14.6 6.7 18.5 8.6 18.0 22.2 70.5 40.5 6.3 16.8 13.2 25.8 65.3 21.5 12.6 8.3 9.5 4.3 25.1 40.2 7.6 9.6 6.1 7.7 5.7 16.1 8.7 6.5 14.8 81.2 11.7 11.0 20.3 49.1 13.2 8.3 6.6 29.6 13.5 16.3 4.6 6.3 14.4 3.4 1.1 3.7 1.5 19.1 14.6 31.2 14.9 29.6 53.1 39.2 24.4 20.1 21.8 18.0 24.0 25.5 27.9 21.2 36.4 6.4 7.9 9.8 21.5 21.9 37.4 6.7 20.9 11.0 62.8 25.0 9.9 0.9 47.6 9.8 53.8 24.1 21.9 56.7 15.8 13.5 0.0 57.3 10.4 23.1 6.2 15.8 7.3 23.2 28.0 21.3 0.1 14.5 6.7 12.2 20.4 16.8 0.0 18.2 30.1 3.9 18.1 71.2 43.4 18.6 12.5 29.0 0.0 0.0 17.0 28.0 12.7 31.7 6.9 3.3 0.0 2.4 3.4 1.8 3.5 3.3 1.7 1.1 4.6 2.5 2.7 14.4 1.1 3.0 6.3 3.7 1.5 68.3 56.3 14.5 38.9 70.5 40.5 65.3 21.5 40.2 49.1 17.9 22.9 29.6 34.7 26.7 120.4 66.8 25.5 14.7 36.4 17.4 47.1 11.0 0.0 53.8 23.8 54.9 6.3 0.0 45.6 16.9 45.6 49.1 22.1 38.2 32.1 33.4 16.7 59.5 23.4 28.3 50.9 37.5 18.6 87.4 12.9 60.6 85.8 13.1 16.3 4.4 7.3 51.8 51.5 20.6 82.8 21.5 6.5 25.3 12.4 35.8 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21754500-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069" Approved NA NA 250000 "CAB004229: AB_627547, HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 16.1 21.1 32.9 18.3 80.3 20.2 13.6 31.0 54.5 18.6 18.5 23.2 9.6 13.7 17.4 10.6 25.7 16.9 14.9 22.8 32.4 23.4 21.7 16.4 19.9 16.6 18.4 23.6 16.0 19.8 27.4 10.9 17.2 27.6 16.4 19.9 14.2 15.8 17.8 28.2 17.5 15.1 22.8 20.4 19.8 17.2 24.2 21.5 19.5 23.0 11.1 21.4 17.7 15.3 2.5 3.2 13.5 4.9 7.0 13.7 2.5 19.7 12.5 16.1 9.2 19.1 19.2 6.1 21.8 20.4 19.6 19.0 9.9 10.5 10.9 10.9 29.2 18.0 18.8 18.9 17.4 25.6 44.0 17.7 19.8 11.7 11.6 15.7 27.8 20.6 14.3 14.0 23.7 21.9 15.4 26.7 11.9 81.1 12.5 23.9 8.1 18.0 6.1 6.1 26.8 12.3 19.8 39.7 2.9 11.2 16.2 13.1 7.3 23.6 14.2 12.7 16.7 10.7 9.4 23.3 16.4 21.4 18.8 13.8 12.0 14.6 17.0 15.5 13.6 17.7 1.0 4.0 5.8 13.7 4.6 3.9 2.0 2.9 4.9 3.2 2.5 2.8 5.1 13.5 7.0 4.9 3.2 2.7 2.5 32.9 80.3 31.0 54.5 32.4 23.4 18.4 23.6 27.6 21.5 44.7 30.2 28.0 22.1 53.3 23.8 34.6 63.7 21.4 33.0 48.8 51.1 18.0 16.6 24.0 33.2 31.2 46.6 23.3 33.6 18.2 31.5 37.5 93.2 59.4 47.7 27.0 57.3 57.7 88.6 9.9 30.2 59.7 38.8 15.4 44.2 32.3 39.5 28.8 41.8 37.6 21.0 32.3 32.2 70.0 47.7 54.1 16.0 95.8 30.7 34.8 MAPK10 "JNK3, p493F12, p54bSAPK, PRKM10" ENSG00000109339 "Mitogen-activated protein kinase 10" P53779 4 85990007-86594625 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.3" "Cell type enhanced" "Detected in many" 16 "Ciliated cells: 92.3;Early spermatids: 179.3;Late spermatids: 303.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "AF22: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022625 Approved NA NA "CAB022625: " "unprognostic (2.46e-2)" "unprognostic (4.36e-2)" "unprognostic (1.13e-1)" "unprognostic (4.05e-2)" "unprognostic (5.17e-2)" "unprognostic (2.03e-1)" "unprognostic (4.59e-2)" "unprognostic (4.82e-2)" "unprognostic (3.81e-2)" "unprognostic (4.45e-2)" "unprognostic (1.18e-3)" "unprognostic (3.02e-2)" "prognostic favorable (3.11e-4)" "unprognostic (1.92e-2)" "unprognostic (1.44e-1)" "unprognostic (6.22e-3)" "prognostic favorable (5.57e-4)" 17.2 11.9 31.6 3.7 34.5 9.7 6.2 26.1 58.3 11.4 4.0 12.6 8.1 3.2 11.0 14.2 7.4 11.9 10.4 5.1 36.0 28.6 15.0 2.7 6.5 3.9 31.5 36.4 11.3 5.6 10.9 31.5 3.4 37.9 16.6 4.3 5.4 3.4 18.9 2.0 3.5 3.9 11.4 23.1 5.3 4.3 18.2 15.8 0.0 15.3 0.4 3.6 11.1 10.2 3.7 3.0 6.9 1.8 3.3 3.6 2.3 1.1 2.0 60.3 1.9 1.7 1.4 2.3 1.2 1.1 1.0 0.5 1.1 1.8 2.6 2.0 0.7 1.5 3.7 0.6 1.6 1.7 3.8 1.6 2.2 2.4 1.9 1.4 1.0 1.2 1.6 0.8 1.4 1.9 2.1 1.3 1.8 1.9 9.9 0.7 1.6 1.7 1.1 3.5 0.3 1.2 1.9 1.5 0.9 4.3 6.4 3.6 3.3 1.2 4.9 0.8 2.0 3.5 1.3 2.8 2.6 2.7 1.1 1.0 3.2 1.9 1.7 3.8 1.3 1.4 6.9 1.8 3.3 2.3 1.6 2.4 3.7 1.9 2.5 1.6 3.3 2.7 3.6 6.2 3.3 1.5 3.0 2.7 2.3 31.6 34.5 26.1 58.3 36.0 28.6 31.5 36.4 37.9 15.8 20.8 26.0 0.0 12.6 0.7 19.8 0.8 12.7 92.3 15.9 21.0 5.9 0.3 10.0 2.1 179.3 1.1 0.0 0.0 0.0 0.5 1.5 10.1 2.3 0.0 0.2 36.5 2.4 1.8 0.3 303.7 24.5 2.5 1.7 0.0 0.0 16.4 1.7 0.0 51.6 16.2 10.2 6.5 2.0 8.8 2.2 0.9 0.1 0.0 0.0 17.9 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Endothelial cells: 13.2;Ito cells: 14.7;Rod photoreceptor cells: 10.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria NA NA Mitochondria "CAB012961: AB_2533144, HPA045069: AB_2679207" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 20.4 5.7 14.2 7.5 17.3 0.8 8.2 22.0 23.7 6.6 2.7 2.8 1.0 1.9 8.2 6.2 5.3 7.0 8.8 8.8 11.7 9.1 5.0 1.5 8.5 8.5 7.2 19.9 5.3 3.1 6.4 10.9 8.4 6.6 7.2 2.7 4.1 5.7 8.0 5.0 6.4 2.6 9.8 5.5 7.3 4.6 3.1 4.1 0.9 4.5 5.3 6.1 6.0 4.4 1.1 0.0 0.0 0.3 0.0 0.9 0.0 1.7 4.2 4.7 17.6 6.2 9.4 0.1 6.6 4.7 4.4 1.7 1.7 3.2 0.0 5.9 6.1 7.3 4.3 3.1 2.6 0.3 9.1 2.1 6.2 5.6 0.4 7.1 1.5 9.7 13.0 7.8 1.2 0.5 4.9 9.6 6.7 5.0 17.0 4.3 7.5 0.3 5.7 0.4 5.2 4.9 17.0 0.1 6.0 6.6 0.0 4.4 11.8 5.6 2.3 4.6 0.6 7.7 4.9 15.0 13.2 11.0 0.9 2.4 0.7 2.0 7.2 6.7 1.8 11.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.4 0.2 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 14.2 17.3 22.0 23.7 11.7 9.1 7.2 19.9 6.6 4.1 0.0 1.4 1.3 1.1 1.6 2.6 2.8 0.0 0.0 0.0 0.0 5.9 0.0 1.7 0.8 3.7 13.2 0.0 0.0 0.2 0.3 1.7 3.3 0.0 1.0 0.2 0.0 0.0 14.7 2.6 5.7 2.8 0.0 5.0 0.0 0.0 5.6 0.7 0.0 2.1 1.4 10.9 0.0 1.0 1.2 2.1 1.1 0.0 1.0 0.0 0.9 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261825 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 104.2" "Cell type enhanced" "Detected in many" 8 "Ito cells: 22.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 31 "NK-cell: 3.0" "Lineage enriched" "Detected in single" 31 "NK-cells: 3.0" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 35.4" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "CAB025483: , HPA054562: AB_2682524" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 3.0 1.6 4.5 2.1 4.5 1.0 1.8 9.0 7.0 2.1 1.4 2.1 1.6 2.0 5.4 5.1 3.3 2.9 2.4 5.1 3.9 3.6 2.5 1.0 2.1 2.0 3.5 5.7 3.0 1.4 1.2 7.0 2.3 2.6 2.9 1.1 2.2 1.4 3.7 104.2 0.9 1.5 4.2 2.6 1.6 1.5 1.6 2.4 0.0 1.3 10.8 1.1 2.4 1.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 10.4 6.4 2.5 7.5 5.7 6.3 3.5 8.0 6.9 13.4 8.5 9.3 3.3 19.6 10.9 8.8 8.0 7.0 11.1 1.6 2.6 5.6 15.6 12.8 19.5 11.5 18.1 12.0 25.4 13.5 2.9 3.0 0.0 7.3 15.2 1.8 11.3 18.2 6.2 5.7 0.0 16.0 7.5 3.5 10.5 18.3 6.7 19.9 7.9 1.4 8.6 2.9 6.2 0.2 9.9 1.9 3.4 14.0 7.9 13.9 12.5 3.0 5.0 4.2 3.2 10.5 3.5 11.3 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 4.5 4.5 9.0 7.0 3.9 3.6 3.5 5.7 2.6 2.4 0.0 5.6 1.3 0.4 0.7 5.1 7.8 2.5 1.4 0.0 0.0 0.0 0.3 1.7 0.4 0.3 9.5 0.0 0.0 0.0 1.8 2.8 3.0 10.4 1.0 4.9 1.6 1.7 22.1 2.8 1.3 6.1 0.8 0.0 1.0 0.0 5.1 0.6 0.0 3.5 6.5 1.7 6.5 2.4 0.2 9.7 0.5 0.3 1.0 0.2 0.0 MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 143.1;Late spermatids: 214.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 16.5;T-cells: 27.8" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.2;RPMI-8226: 27.9;RT4: 28.9" "Region enhanced" "Detected in some" "cerebellum: 6.5" "Region enriched" "Detected in some" 15 "cerebellum: 59.9" "HPA007667, CAB025854" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favorable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" 6.5 22.0 2.2 5.4 4.0 2.9 6.8 2.8 7.3 6.8 18.9 0.5 36.8 18.8 1.9 10.3 41.1 2.4 12.0 1.2 1.7 1.8 6.5 2.8 9.6 11.2 0.8 3.8 3.9 24.6 18.8 12.4 10.5 2.5 6.8 16.0 2.4 20.7 26.3 0.9 28.6 37.7 2.1 0.8 5.9 12.2 23.7 1.1 5.0 13.8 16.0 18.5 7.3 13.9 16.5 0.1 5.2 0.3 2.8 27.8 6.7 19.6 0.1 0.3 0.2 1.2 5.7 2.7 1.6 0.2 0.2 0.5 16.3 19.4 4.7 1.2 1.5 2.8 15.2 0.0 46.2 0.4 12.0 5.2 0.1 0.5 16.2 2.0 0.1 1.2 4.9 16.4 3.0 0.6 2.3 3.0 0.5 0.3 5.3 0.5 10.3 0.1 1.2 0.1 19.4 0.3 11.6 0.2 27.9 9.0 28.9 19.6 0.3 1.7 0.3 0.1 0.6 22.0 2.5 4.1 1.4 0.2 0.5 0.3 0.3 7.0 1.4 0.0 0.5 0.1 5.2 0.3 4.5 16.2 0.0 10.5 10.8 11.6 13.0 0.1 16.5 10.6 11.9 3.9 2.8 0.0 0.0 27.8 6.7 2.2 4.0 2.8 7.3 1.7 1.8 0.8 3.8 2.5 1.1 26.8 24.1 11.5 34.8 24.3 0.8 1.6 22.9 1.4 22.7 27.9 5.9 41.4 13.3 48.4 89.5 2.3 143.1 0.0 102.6 8.3 3.2 28.0 2.3 1.6 35.8 0.0 63.0 0.6 6.1 214.3 6.6 6.4 16.9 22.6 80.8 1.5 76.0 89.2 9.2 7.9 2.2 0.0 1.0 6.1 1.5 46.5 27.0 20.2 93.7 47.8 MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 32.1;neutrophil: 12.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 32.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" NA NA 7100000 "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" 21.5 20.6 11.7 18.4 15.5 49.9 20.7 26.5 18.1 22.0 20.5 12.5 11.9 16.9 38.8 12.1 24.0 18.9 16.0 16.4 9.3 9.5 16.0 29.8 21.5 29.0 12.0 11.3 17.7 18.5 15.0 27.2 27.3 10.2 23.4 18.3 17.0 16.7 16.5 21.2 25.6 22.5 26.0 10.6 35.5 18.2 11.1 10.3 34.1 20.9 17.6 20.8 25.0 30.0 2.3 4.0 32.1 4.9 3.0 2.8 2.1 18.5 10.2 11.0 17.7 25.1 25.0 24.2 19.4 25.3 23.0 24.0 24.9 9.6 15.0 19.3 21.3 11.0 13.3 18.1 16.8 24.1 16.9 14.5 34.7 14.5 20.8 13.8 21.9 21.0 17.6 16.4 16.6 16.5 19.2 26.1 26.0 19.2 18.9 15.7 8.8 22.4 26.3 6.7 11.4 10.2 26.7 17.9 13.9 16.2 25.6 8.3 7.0 17.5 13.1 20.3 14.1 15.4 40.9 18.3 20.7 12.0 13.0 17.7 9.3 21.2 15.1 9.4 43.2 16.9 32.1 4.9 3.0 2.4 3.5 2.8 1.5 2.2 2.6 4.0 2.3 2.5 2.4 12.3 3.0 4.7 1.9 2.6 2.1 11.7 15.5 26.5 18.1 9.3 9.5 12.0 11.3 10.2 10.3 29.8 11.5 18.2 10.6 14.2 19.3 23.5 7.6 16.0 19.4 17.4 29.5 38.2 1.7 12.1 2.6 20.2 25.7 0.0 9.9 14.8 20.9 9.0 20.7 39.4 22.3 11.1 16.1 21.5 58.1 3.7 22.7 30.0 10.1 19.8 22.5 12.2 17.6 20.3 25.1 14.0 24.3 12.9 11.5 6.3 7.7 16.7 20.0 23.5 15.6 8.8 MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716259-143722458 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.9;epididymis: 27.6;fallopian tube: 29.5" "Cell type enriched" "Detected in some" 6 "Ciliated cells: 85.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "pons and medulla: 26.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.2;HaCaT: 5.4;HeLa: 14.3;MCF7: 13.9;T-47d: 12.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Nucleoplasm, Cytosol" "Cell Junctions" "HPA002704: AB_1079307" "unprognostic (9.11e-2)" "unprognostic (1.38e-1)" "unprognostic (8.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.54e-2)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (2.59e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-1)" "unprognostic (9.51e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (5.78e-1)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" 0.6 0.1 3.6 0.3 8.1 0.1 1.1 0.2 2.1 4.5 0.4 8.7 5.2 0.5 2.2 27.6 1.3 29.5 0.4 1.1 5.4 4.6 3.9 0.2 7.4 0.5 0.2 1.5 4.7 2.0 9.1 4.2 0.6 26.9 0.9 0.4 1.6 3.0 2.4 0.2 4.9 0.7 0.5 0.4 0.5 0.9 7.3 2.4 0.1 8.4 0.5 0.4 0.5 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.7 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 7.2 0.0 1.3 0.0 0.0 5.4 0.1 0.2 0.0 1.1 1.6 0.0 14.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.3 2.7 0.0 0.0 13.9 0.0 0.0 2.0 1.2 1.1 0.0 3.0 0.4 0.9 1.3 4.0 4.0 0.0 2.8 0.0 0.2 12.5 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 8.1 0.2 2.1 5.4 4.6 0.2 1.5 26.9 2.4 0.0 8.3 0.0 0.2 0.3 0.0 0.8 0.0 85.6 13.6 0.0 0.0 0.0 0.0 0.6 12.6 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 2.7 0.7 0.3 0.1 0.0 0.1 0.0 MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 255.2;Enterocytes: 275.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 25.1;neutrophil: 11.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 25.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" 24.9 18.5 63.3 15.3 43.2 15.6 21.1 24.8 52.0 21.3 45.1 30.4 6.3 39.7 24.2 11.4 44.1 28.7 25.6 21.2 37.1 34.0 13.4 8.8 23.3 13.1 33.8 27.4 32.7 13.0 26.1 15.2 27.6 27.6 20.1 36.7 26.2 17.1 18.3 13.9 18.7 49.2 24.0 27.8 15.9 33.7 11.6 19.5 8.4 20.5 18.7 26.0 18.2 22.2 1.4 1.5 25.1 2.7 0.8 3.1 1.4 14.0 7.7 16.4 9.2 41.2 54.6 9.2 10.5 26.0 16.6 19.9 9.1 28.2 14.1 10.4 29.3 19.2 5.2 13.7 12.3 16.3 26.7 15.9 4.3 8.5 15.3 41.4 3.2 12.1 33.7 7.2 19.0 8.6 25.3 42.2 15.5 5.9 18.2 22.0 36.8 14.5 5.0 4.3 28.6 6.7 17.2 9.7 31.7 15.2 8.9 14.5 10.3 6.0 21.1 6.1 13.8 13.8 7.7 29.9 11.0 9.5 12.5 3.6 20.7 9.4 7.2 22.0 6.8 7.7 2.4 2.7 25.1 0.9 1.9 1.4 1.3 2.1 1.6 1.4 1.4 1.5 1.6 11.3 0.8 1.0 1.5 3.1 1.4 63.3 43.2 24.8 52.0 37.1 34.0 33.8 27.4 27.6 19.5 20.8 20.3 9.0 19.0 8.8 28.0 12.7 15.3 20.1 7.9 8.7 21.6 66.6 19.9 31.0 255.2 49.5 275.3 0.0 54.5 107.4 25.7 11.8 2.3 6.4 38.5 7.9 52.6 52.8 25.3 107.0 30.0 18.9 21.9 27.9 135.6 38.1 77.0 98.1 25.8 18.2 32.7 19.4 18.6 10.5 17.5 11.5 28.3 13.1 63.5 18.0 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560078-50731824 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.4;brain: 33.4;parathyroid gland: 43.5" "Cell type enhanced" "Detected in some" 15 "Cardiomyocytes: 20.1;Early spermatids: 20.2;Late spermatids: 42.4;Muller glia cells: 55.0" "Group enriched" "Detected in many" 5 "glioma: 15.2;melanoma: 3.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.0;HeLa: 4.5;NTERA-2: 3.0;SCLC-21H: 15.7;SH-SY5Y: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" NA NA "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 1.9 26.4 16.9 1.1 33.4 0.9 1.8 15.9 23.9 1.4 2.6 9.5 3.8 1.6 1.8 4.5 3.5 1.5 3.0 16.9 13.0 14.3 4.5 7.0 3.5 0.9 17.1 9.1 4.2 2.5 43.5 8.3 3.7 20.5 5.3 1.8 4.1 1.8 12.4 1.7 1.0 1.9 5.2 11.8 1.1 1.3 3.5 12.4 1.7 7.8 0.0 0.9 2.2 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 1.5 1.4 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.9 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 15.7 3.8 0.1 1.1 2.6 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 33.4 15.9 14.5 13.0 14.3 17.1 9.1 20.5 12.4 8.9 0.0 0.0 0.1 0.0 11.0 20.1 2.5 0.0 0.0 0.0 0.0 3.6 5.0 1.0 20.2 0.0 0.0 0.0 0.0 0.3 0.4 0.8 0.0 0.8 0.3 4.8 0.0 0.0 0.0 42.4 0.9 0.0 0.0 0.0 0.0 55.0 0.5 0.0 1.4 0.0 0.6 0.0 1.0 0.6 0.6 0.0 1.5 0.0 0.0 0.0 MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067372 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262, HPA047825" Approved Supported Supported Cytosol NA NA Cytosol "CAB005184: AB_2140298, HPA030262: AB_10601868, HPA047825: " "unprognostic (6.61e-2)" "unprognostic (1.75e-2)" "unprognostic (5.05e-2)" "unprognostic (3.40e-3)" "unprognostic (2.72e-1)" "unprognostic (5.52e-2)" "unprognostic (6.13e-2)" "unprognostic (2.32e-3)" "unprognostic (3.99e-2)" "unprognostic (8.54e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-3)" "unprognostic (2.03e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (2.31e-2)" 11.8 7.4 14.4 10.9 23.2 25.6 13.7 33.0 24.5 16.3 18.7 12.5 9.3 16.3 15.9 13.3 32.3 8.2 17.0 9.1 13.3 15.9 14.4 32.6 12.6 9.4 13.1 16.8 11.5 8.5 12.2 15.3 13.9 23.8 10.5 18.1 9.5 17.9 11.4 27.1 24.0 26.2 17.8 14.2 9.2 15.7 25.7 13.0 11.7 13.4 22.7 12.4 18.9 22.4 4.9 4.2 3.0 4.5 6.5 7.9 3.6 8.7 11.8 23.3 8.9 7.2 11.9 17.1 12.6 12.7 11.6 13.7 14.1 5.3 12.6 8.8 16.1 17.0 12.4 17.9 23.9 15.9 7.7 5.6 18.8 7.0 22.4 17.5 14.0 40.2 12.7 44.0 14.0 36.5 12.4 10.9 8.7 24.3 21.6 14.8 19.8 9.8 11.1 8.3 10.9 5.7 8.6 15.0 20.3 11.1 36.9 11.5 10.8 10.1 8.3 18.3 33.7 7.5 20.9 10.8 13.9 15.0 9.0 16.7 11.2 32.9 15.7 17.2 20.6 17.0 3.0 4.5 1.2 3.8 4.3 4.7 4.9 5.6 4.3 4.2 2.6 5.4 3.8 0.6 6.5 2.8 1.9 7.9 3.6 14.4 23.2 33.0 24.3 13.3 15.9 13.1 16.8 23.8 13.0 26.8 29.8 23.8 84.4 99.5 34.6 20.2 22.9 24.1 29.6 15.7 15.7 14.3 14.9 31.8 133.3 22.8 95.4 0.0 43.1 33.7 40.4 80.6 139.2 47.8 25.7 31.8 29.7 16.5 30.7 167.7 21.0 26.7 28.7 11.8 32.2 25.1 52.1 31.6 22.3 30.5 21.1 19.4 21.7 56.4 75.8 96.7 27.7 17.0 19.8 153.6 MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Sertoli cells: 25.8;Spermatocytes: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 24.1;SuSa: 29.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: AB_2673706" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.5 15.0 6.4 7.3 7.6 9.2 11.8 12.5 7.9 13.4 15.3 7.2 6.0 9.2 13.1 14.1 17.3 9.4 11.8 8.2 5.9 4.7 10.8 4.8 9.9 9.2 8.2 5.2 25.4 5.7 7.3 7.5 12.5 6.7 14.0 6.9 10.5 7.8 12.3 7.5 13.1 11.2 13.8 7.1 13.2 8.0 13.3 7.5 4.5 8.6 11.3 10.6 12.7 15.9 2.2 2.6 11.5 7.4 5.5 4.7 3.0 3.6 5.8 4.8 3.7 24.1 10.1 5.6 5.0 4.6 6.9 6.4 6.7 0.6 2.2 4.0 8.6 5.1 4.1 5.6 4.6 4.3 3.8 4.3 1.0 4.1 2.9 10.4 0.9 3.7 10.6 3.2 10.5 3.7 6.0 5.1 4.3 1.9 0.8 6.9 2.4 7.4 3.9 5.5 3.7 3.8 4.0 7.0 1.5 2.3 2.0 2.2 6.4 5.1 0.5 2.5 29.6 3.1 1.2 2.8 7.4 5.5 8.2 3.4 1.4 2.1 0.6 8.6 0.9 4.5 1.0 3.6 11.5 4.7 7.4 2.5 2.2 2.2 4.1 2.6 1.4 2.1 2.6 1.3 5.5 6.5 1.7 1.0 3.0 6.4 7.6 12.5 7.9 5.9 4.7 8.2 5.2 6.7 7.5 6.0 3.5 6.2 5.5 4.8 2.0 1.7 0.0 1.4 2.3 5.2 2.0 4.8 5.0 7.1 6.3 7.1 9.0 0.0 5.3 6.9 8.3 5.5 2.3 1.3 6.7 0.0 10.3 6.7 6.7 5.9 10.6 6.3 3.3 2.8 5.7 14.5 6.2 13.5 11.0 3.0 2.0 25.8 8.6 31.4 10.6 3.8 4.2 4.4 6.1 5.2 MAPK8 "JNK, JNK1, PRKM8, SAPK1" ENSG00000107643 "Mitogen-activated protein kinase 8" P45983 10 48306639-48439360 "Cancer-related genes, Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004463, CAB069396" Approved NA NA "CAB004463: AB_675868, CAB069396: AB_1619977" "unprognostic (7.49e-2)" "unprognostic (1.47e-1)" "unprognostic (2.74e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (8.66e-4)" "unprognostic (4.23e-2)" "unprognostic (5.98e-2)" "unprognostic (4.31e-3)" "unprognostic (2.33e-1)" "unprognostic (6.06e-2)" "prognostic favorable (8.66e-4)" "unprognostic (1.58e-1)" "unprognostic (9.95e-2)" "unprognostic (1.85e-2)" "unprognostic (1.01e-3)" 13.4 11.7 15.3 11.5 18.5 13.3 22.1 33.6 35.2 15.2 13.9 12.9 19.5 16.7 17.1 10.8 16.1 12.4 15.1 11.2 20.0 18.0 20.1 23.6 11.7 12.0 15.9 16.7 18.9 15.3 12.7 23.7 12.2 23.6 13.0 14.3 12.4 17.2 15.9 18.9 10.8 17.7 14.6 13.7 9.6 12.2 23.4 12.2 20.5 22.3 9.0 13.8 11.8 13.0 4.5 4.3 5.2 4.3 4.7 5.7 3.5 16.0 4.3 14.5 8.3 5.6 6.6 11.3 24.2 16.6 14.5 11.9 5.0 16.6 5.8 6.6 13.5 7.6 9.8 5.0 9.3 19.0 34.7 8.3 8.3 5.0 6.8 9.2 14.2 9.8 5.5 10.7 10.8 21.4 8.6 13.3 16.1 13.3 10.7 9.4 4.7 17.3 7.6 9.1 5.8 3.2 11.4 15.0 5.8 8.9 6.2 24.4 19.4 9.4 7.9 10.9 9.8 8.6 6.8 11.4 10.8 26.0 8.2 18.2 3.4 8.3 11.8 7.5 15.1 6.2 0.0 3.3 3.0 4.1 2.8 4.7 4.5 5.7 5.0 3.3 2.9 5.6 3.9 5.2 4.7 4.3 4.3 2.9 3.5 15.3 18.5 33.6 35.2 20.0 18.0 15.9 16.7 23.6 12.2 3.0 11.3 7.8 38.8 39.8 58.6 8.3 22.9 14.7 14.8 7.0 29.5 11.7 10.0 24.2 142.4 17.8 21.0 0.0 22.3 5.8 15.8 35.2 11.5 16.3 8.8 66.7 29.7 8.6 9.9 66.1 13.6 16.2 20.3 31.5 12.5 21.2 25.4 15.0 9.6 19.2 34.4 6.5 25.8 22.7 25.1 32.0 13.2 11.5 11.5 38.7 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "basophil: 13.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.2" "Cell line enhanced" "Detected in all" "HDLM-2: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008910 Enhanced NA NA "CAB008910: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favorable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 10.3 12.4 22.9 9.6 31.8 10.3 11.4 48.7 41.4 10.8 12.4 10.6 4.7 10.1 8.7 9.5 8.7 8.8 7.8 14.0 24.3 25.0 12.2 9.7 10.8 10.0 22.0 21.0 8.5 25.9 16.3 8.8 10.9 29.4 11.7 15.3 7.0 9.9 13.1 20.5 6.3 10.4 11.4 16.8 8.6 12.3 9.4 10.3 7.1 15.4 5.1 11.3 9.9 7.3 1.4 1.4 13.2 2.4 1.3 3.1 0.3 17.2 14.3 12.6 15.8 12.5 14.1 27.2 16.6 14.8 14.0 14.1 18.7 12.3 18.5 28.7 17.6 30.8 13.3 13.0 27.9 16.5 69.4 12.5 7.7 15.9 13.3 9.5 15.9 13.5 10.3 12.5 13.6 13.2 14.6 16.6 14.5 8.4 13.4 19.0 22.6 15.8 6.6 8.8 21.4 8.5 15.3 21.5 8.8 10.6 16.5 14.6 10.3 19.5 19.0 13.2 16.4 19.3 13.8 11.9 16.8 16.9 23.6 24.8 9.7 11.4 12.6 17.8 14.9 11.1 13.2 0.6 2.5 2.0 1.3 2.0 1.0 1.5 1.8 1.0 1.4 1.0 1.2 0.9 1.3 2.4 1.4 3.1 0.3 22.9 31.8 48.7 41.4 24.3 25.0 22.0 21.0 29.4 10.3 29.8 11.8 11.5 6.1 9.0 18.3 20.7 10.2 5.3 10.3 8.7 15.7 12.1 5.0 7.1 0.9 15.7 13.5 0.0 13.9 18.8 9.9 10.0 11.5 15.3 10.3 12.7 16.0 13.5 17.2 2.3 9.8 12.8 5.0 10.0 17.1 10.4 10.9 11.5 12.7 9.2 14.2 12.9 7.2 15.9 17.0 9.9 14.9 8.6 14.5 7.3 MAPKAPK2 ENSG00000162889 "Mitogen-activated protein kinase-activated protein kinase 2" P49137 1 206684944-206734283 "Cancer-related genes, Enzymes, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in all" 6 "dendritic cells: 18.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported Nucleoplasm,Centrosome NA NA Nucleoplasm Centrosome "CAB010297: AB_2250405, HPA045556: AB_2679367, HPA063708: AB_2685100, HPA064435: AB_2685263" "unprognostic (7.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (4.58e-6)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (6.96e-2)" "unprognostic (3.29e-2)" 23.0 25.3 11.6 21.2 15.7 58.6 23.9 11.1 14.5 19.3 25.6 17.2 14.5 25.7 20.0 18.5 23.5 17.3 26.0 89.2 12.3 8.7 33.7 26.7 26.7 21.5 16.7 6.5 23.3 19.1 16.9 22.8 13.6 15.7 20.2 14.4 17.8 19.8 14.4 62.9 18.3 32.9 18.3 14.6 37.7 23.1 21.3 14.6 26.9 24.3 25.2 28.2 22.9 46.1 1.1 18.7 3.2 1.1 2.3 1.6 0.5 21.2 8.4 11.7 13.2 34.6 20.3 14.6 14.8 33.7 22.7 21.4 16.1 10.4 10.2 10.4 29.9 14.2 16.1 8.7 15.8 16.3 11.9 6.6 17.2 10.5 10.3 26.7 25.4 57.6 28.0 20.2 21.8 24.1 18.9 18.5 13.9 19.8 46.7 18.3 26.4 10.2 18.4 13.5 7.5 11.8 26.2 24.6 3.3 17.1 13.1 9.4 12.1 17.5 29.6 20.5 22.8 14.4 24.7 17.6 20.5 17.3 23.7 20.2 60.9 54.0 8.3 23.2 15.5 6.7 1.1 0.7 1.4 1.6 1.1 1.5 1.0 1.2 1.5 0.6 1.1 0.6 1.1 3.2 2.3 1.0 18.7 1.4 0.5 11.6 15.7 11.1 14.5 12.3 8.7 16.7 6.5 15.7 14.6 50.6 53.7 28.9 47.2 75.9 11.3 97.2 40.8 6.7 29.6 29.6 19.6 5.0 13.3 28.0 71.3 26.3 27.4 23.3 50.4 7.0 28.6 55.9 34.6 34.4 22.4 0.0 59.3 21.5 27.7 20.1 21.0 27.9 32.1 12.6 32.0 17.7 50.5 21.2 16.3 21.0 14.8 25.8 48.7 11.8 4.1 63.0 13.8 37.4 24.1 68.1 MAPKAPK3 "3pK, MAPKAP3" ENSG00000114738 "Mitogen-activated protein kinase-activated protein kinase 3" Q16644 3 50611520-50649297 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 86.7;skeletal muscle: 70.1" "Cell type enhanced" "Detected in many" 9 "Cardiomyocytes: 193.9;Hofbauer cells: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 30.2;eosinophil: 23.0;intermediate monocyte: 50.0;myeloid DC: 27.1;neutrophil: 20.5;non-classical monocyte: 61.4;plasmacytoid DC: 16.9" "Group enriched" "Detected in all" 5 "dendritic cells: 27.1;granulocytes: 23.0;monocytes: 61.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm NA NA Nucleoplasm "HPA058275: AB_2683663" "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favorable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" 8.9 16.1 5.6 9.3 7.2 30.4 6.3 1.9 6.2 5.5 9.5 7.1 7.5 9.9 5.5 8.6 16.8 5.1 8.5 86.7 4.8 3.7 17.9 11.9 11.0 15.1 7.2 4.1 8.7 24.2 11.2 9.0 9.0 6.0 7.6 6.7 10.9 12.4 9.2 70.1 17.6 12.0 5.2 5.9 12.5 9.0 4.0 5.2 25.9 22.6 40.9 14.3 6.1 7.5 3.0 27.1 23.0 61.4 7.3 6.4 19.5 23.4 7.3 3.0 8.6 4.6 11.7 6.9 5.7 8.2 8.8 7.5 11.3 21.9 9.4 5.8 19.1 21.9 8.4 20.9 22.5 7.9 20.8 5.0 49.5 10.3 10.2 9.3 35.6 26.4 9.3 14.0 20.5 28.0 8.8 7.8 16.8 13.9 6.2 18.5 9.5 15.1 35.9 11.4 8.2 30.0 6.7 7.3 14.2 41.0 13.5 5.7 4.0 5.1 14.5 6.5 5.3 9.1 22.1 5.6 7.0 16.0 36.0 14.1 4.2 7.7 7.8 37.0 56.1 2.8 6.4 30.2 23.0 5.5 50.0 5.4 3.0 6.2 6.4 27.1 1.8 4.9 5.5 20.5 7.3 61.4 16.9 5.2 19.5 5.6 7.2 1.9 6.2 4.8 3.7 7.2 4.1 6.0 5.2 8.9 9.4 7.5 19.5 10.1 0.9 193.9 10.2 6.7 6.8 10.4 0.0 5.0 54.7 35.3 28.4 6.7 23.1 0.0 26.4 5.7 11.0 21.5 35.7 10.9 91.5 0.0 5.8 4.9 48.9 60.2 6.6 40.9 6.8 46.9 13.9 10.8 54.8 8.6 3.2 28.5 2.3 25.8 11.7 3.4 4.3 17.7 4.2 18.7 27.9 30.1 MAPKAPK5 PRAK ENSG00000089022 "Mitogen-activated protein kinase-activated protein kinase 5" Q8IW41 12 111841978-111902238 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "CAB004546: AB_627910, HPA015515: AB_1853569" "unprognostic (6.45e-2)" "unprognostic (7.29e-2)" "unprognostic (1.27e-3)" "unprognostic (1.09e-2)" "unprognostic (5.52e-2)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.98e-8)" "unprognostic (1.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (3.20e-1)" "unprognostic (6.03e-2)" "unprognostic (3.39e-2)" "unprognostic (9.41e-2)" "unprognostic (3.25e-2)" 20.7 26.2 21.4 17.5 26.4 24.1 21.7 23.7 28.3 17.3 28.8 26.1 21.9 26.3 25.8 22.8 20.8 17.5 22.7 20.7 17.7 15.2 21.7 21.5 18.9 19.4 22.3 20.4 21.3 24.5 19.8 20.4 21.0 17.3 18.7 32.9 23.6 23.3 20.5 33.2 23.0 28.4 21.1 18.0 18.4 19.8 16.7 22.0 19.3 20.5 15.1 19.3 19.9 16.5 4.9 4.1 3.2 11.4 3.9 6.8 2.5 14.9 19.8 19.2 16.1 13.9 14.1 29.3 15.0 18.1 23.0 16.0 25.6 12.3 22.6 11.1 17.6 13.7 14.9 25.2 15.7 21.6 15.0 13.8 20.1 13.8 20.5 16.8 25.2 14.2 14.8 22.6 22.0 26.2 17.5 16.9 20.6 27.7 8.9 16.8 16.8 25.0 39.9 27.3 36.8 14.0 24.8 14.0 21.7 18.3 21.7 23.7 20.1 17.0 29.0 20.8 18.3 23.5 28.9 14.7 13.1 13.2 13.4 18.7 18.3 22.4 26.7 15.9 18.4 18.5 1.3 4.8 3.2 6.5 3.5 3.5 4.9 4.3 4.7 3.3 4.0 6.8 5.1 2.5 3.9 11.4 4.1 6.6 2.5 21.4 26.4 23.7 28.3 17.7 15.2 22.3 20.4 17.3 22.0 3.0 17.2 13.8 19.4 18.2 45.9 15.7 22.9 9.4 15.9 3.5 39.3 26.2 11.6 25.6 11.1 15.5 36.7 0.0 25.7 28.0 17.4 20.5 2.3 11.1 17.5 22.3 35.2 16.5 15.8 5.6 14.4 16.6 8.5 24.4 39.9 19.2 27.7 28.8 16.6 16.8 34.7 19.4 17.9 18.0 36.8 18.6 25.2 22.3 30.8 24.3 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528183-220664461 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 7 "Bipolar cells: 23.6;Cardiomyocytes: 19.9;Cone photoreceptor cells: 29.5;Spermatocytes: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 35.7;SuSa: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain NA NA "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favorable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 14.3 5.6 11.4 4.6 13.5 0.9 9.0 15.2 22.7 9.8 6.7 4.7 6.4 2.1 7.8 26.6 9.4 5.9 5.0 19.1 10.0 12.5 4.7 1.5 4.8 2.3 10.3 12.4 3.7 3.0 5.8 12.1 3.9 13.2 7.2 4.1 6.2 5.0 11.3 4.2 3.5 3.4 10.1 7.1 3.2 4.3 16.0 4.6 0.4 8.4 5.3 5.7 8.8 14.9 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 4.5 1.2 0.0 0.0 1.9 1.5 2.2 1.6 2.4 0.0 0.0 0.0 0.0 0.0 3.3 2.3 9.5 6.2 1.1 0.0 7.0 0.0 2.4 0.0 0.0 0.7 0.9 0.7 5.3 0.0 2.9 0.8 0.2 2.3 0.0 0.0 0.0 0.0 0.0 0.0 8.8 4.5 2.2 0.0 7.1 0.0 0.0 35.7 6.6 5.8 0.3 0.3 0.4 11.1 0.7 0.0 0.0 0.0 3.5 4.8 6.2 0.0 0.0 0.0 1.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.4 13.5 15.2 17.5 10.0 12.5 10.3 12.4 13.2 4.6 0.0 0.3 0.5 2.4 3.1 23.6 19.9 0.0 1.4 2.3 3.5 29.5 1.7 0.0 1.6 5.5 3.0 1.1 0.0 0.0 1.8 3.1 1.7 0.0 0.0 0.2 9.5 8.6 4.3 0.3 3.0 2.0 0.0 0.0 0.0 0.2 15.1 0.1 0.0 6.0 0.0 10.6 0.0 15.1 17.9 5.2 2.9 0.8 0.0 0.4 3.9 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911019 "Enzymes, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 9.7 11.6 16.5 16.3 21.4 18.5 13.8 24.7 26.1 15.2 20.5 20.0 11.1 21.3 13.6 7.5 48.4 13.6 14.4 14.7 17.0 10.1 11.9 12.4 15.4 16.3 18.1 13.7 11.0 17.3 21.8 22.4 21.1 15.0 14.9 19.8 10.6 20.7 14.3 15.7 35.8 26.9 13.3 13.3 21.6 16.8 9.8 18.7 22.9 15.9 13.6 23.5 14.8 21.3 2.9 1.9 9.8 1.9 3.3 4.5 1.2 22.7 15.2 12.5 13.1 6.9 9.0 17.3 9.3 8.9 13.4 10.4 16.3 24.1 16.8 16.4 9.7 14.5 29.5 12.0 14.5 11.6 11.6 9.4 18.5 12.0 10.6 7.7 20.1 24.5 4.9 19.8 12.3 10.7 6.3 11.0 15.9 15.7 19.4 8.8 28.0 21.0 14.3 14.2 18.4 11.1 17.4 9.3 18.6 10.0 18.8 17.2 11.6 16.0 41.1 10.7 14.0 29.9 12.0 10.4 14.2 8.9 18.3 10.3 11.8 12.2 16.5 9.7 10.6 11.3 2.7 1.7 4.4 2.9 1.5 4.5 2.3 3.2 3.1 1.9 2.9 2.6 2.4 9.8 3.3 1.9 1.7 1.5 1.2 16.5 21.4 24.7 26.1 17.0 10.1 18.1 13.7 15.0 18.7 6.0 5.0 13.9 16.2 22.3 26.0 10.9 35.7 6.7 6.8 19.2 7.9 19.2 1.7 18.5 0.4 11.9 59.3 0.0 18.5 16.8 10.6 28.8 17.3 12.1 15.7 19.1 28.7 13.5 19.5 0.7 11.8 11.3 3.3 8.2 35.1 19.1 20.0 35.9 10.3 6.9 17.8 19.4 9.2 8.4 21.8 30.1 54.3 23.6 28.2 30.9 MARK3 "CTAK1, KP78, PAR-1A" ENSG00000075413 "Microtubule affinity regulating kinase 3" P27448 14 103385392-103503831 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 14 "eosinophil: 42.2" "Lineage enriched" "Detected in many" 23 "granulocytes: 42.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024652 Approved NA NA "HPA024652: AB_1853582" "unprognostic (6.86e-2)" "unprognostic (2.93e-1)" "unprognostic (7.70e-2)" "unprognostic (3.48e-2)" "unprognostic (8.41e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-3)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (2.29e-3)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (1.60e-1)" 20.8 31.9 24.6 20.9 29.5 62.7 19.7 59.1 30.2 25.3 20.8 33.2 19.9 17.4 28.5 28.4 24.4 23.1 22.2 33.6 24.9 22.4 20.3 20.1 25.9 20.8 29.6 23.3 24.6 30.7 28.1 30.9 20.5 27.4 19.3 20.0 23.6 18.3 23.1 40.9 19.9 19.2 26.8 20.9 26.8 26.9 24.1 30.3 29.1 25.8 23.1 23.0 20.8 29.0 1.2 1.2 42.2 1.1 0.8 1.8 0.4 13.4 16.3 23.7 17.9 28.5 22.3 20.5 23.8 25.2 28.9 27.8 12.8 21.1 16.0 15.1 22.4 12.5 25.3 25.9 25.7 36.9 18.6 11.5 20.7 17.3 16.0 53.8 23.5 13.8 25.9 23.8 23.4 47.9 26.4 26.7 16.0 21.2 37.4 21.6 36.0 16.1 20.9 17.4 22.7 24.6 21.1 24.3 12.8 25.5 28.6 20.9 20.9 25.3 17.4 23.2 28.1 23.6 20.2 23.0 15.5 11.1 28.9 21.2 24.2 30.7 19.2 18.9 19.0 20.9 0.4 1.1 42.2 1.1 0.8 0.9 1.2 1.6 1.8 1.1 0.9 1.8 1.4 3.1 0.8 0.7 1.2 1.6 0.4 24.6 29.5 59.1 30.2 24.9 22.4 29.6 23.3 27.4 30.3 53.6 64.4 40.2 43.5 39.3 70.1 69.8 35.7 25.4 52.4 36.6 153.2 26.8 10.0 40.4 26.7 50.1 30.4 186.9 36.6 26.3 42.6 53.5 47.3 26.8 26.4 55.6 30.0 47.3 26.0 38.0 56.4 44.1 35.4 50.5 28.7 36.1 46.0 29.2 55.5 15.8 90.5 32.3 43.7 40.2 55.6 45.7 41.1 42.6 28.4 99.3 MARK4 "FLJ90097, KIAA1860, MARKL1, Nbla00650, PAR-1D" ENSG00000007047 "Microtubule affinity regulating kinase 4" Q96L34 19 45079288-45305283 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Horizontal cells: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039186 Approved Supported Cytosol NA NA Cytosol "HPA039186: AB_10796223" "unprognostic (1.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (8.31e-8)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.05e-5)" "unprognostic (1.90e-1)" "unprognostic (2.16e-2)" "unprognostic (6.26e-2)" "unprognostic (5.64e-3)" "unprognostic (1.24e-3)" "unprognostic (7.50e-2)" "unprognostic (3.80e-2)" "unprognostic (6.89e-2)" "unprognostic (7.23e-2)" "unprognostic (4.65e-2)" "unprognostic (3.02e-2)" 11.8 13.0 19.4 10.3 26.0 8.4 15.2 21.9 28.6 11.4 10.2 9.0 12.9 6.6 14.0 17.5 13.5 12.9 13.4 14.7 22.2 15.7 8.7 13.5 11.7 10.5 14.3 21.6 21.0 16.8 13.7 12.9 12.1 15.0 12.2 6.3 14.1 12.1 14.2 40.7 20.6 7.5 14.1 10.8 12.4 10.3 32.1 12.3 11.2 10.5 11.5 9.4 13.7 17.9 1.0 2.8 3.5 2.9 1.8 4.3 1.2 8.9 3.8 15.1 11.0 10.8 17.2 4.2 6.6 10.4 9.9 9.3 2.3 5.1 4.3 5.7 12.1 8.2 6.1 10.7 9.7 5.6 7.9 8.8 8.6 4.7 8.2 19.9 2.1 7.5 21.4 13.8 8.3 9.6 17.5 13.2 9.6 10.9 10.8 10.7 7.5 7.6 6.7 6.5 7.4 3.3 29.6 4.9 2.8 9.3 7.2 28.4 12.5 9.8 8.7 5.1 15.3 4.1 12.5 10.7 8.9 6.8 6.0 4.3 12.1 9.6 4.9 9.5 4.0 7.1 3.5 2.9 0.7 3.4 2.2 0.7 0.9 1.2 4.3 0.8 1.0 2.3 2.6 2.9 1.8 2.0 2.8 2.4 1.2 19.4 26.0 21.9 22.7 22.2 15.7 14.3 21.6 15.0 12.3 11.9 1.9 3.0 9.5 22.1 20.9 7.3 10.2 0.0 2.3 8.7 23.6 3.3 10.0 7.8 2.1 10.5 3.3 0.0 5.3 1.1 7.5 8.5 2.3 10.9 5.8 112.8 5.8 18.4 8.4 4.1 15.0 6.1 3.3 2.8 6.0 13.2 7.3 3.2 13.1 5.6 14.6 0.0 7.3 0.5 6.1 21.1 9.6 6.9 3.4 14.0 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874951 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.0" "Cell type enhanced" "Detected in many" 13 "Bipolar cells: 22.6;Cone photoreceptor cells: 41.2;Early spermatids: 13.0;Horizontal cells: 14.3;Rod photoreceptor cells: 18.7" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "MAIT T-cell: 3.6;T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 3.6" "Cell line enhanced" "Detected in many" "AN3-CA: 15.0;SCLC-21H: 26.5;SH-SY5Y: 13.2;U-266/70: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 1.2 5.2 20.4 1.7 13.6 1.6 1.5 51.0 40.1 1.1 1.5 1.4 0.0 1.7 1.3 1.2 1.3 1.2 1.6 1.3 16.1 16.3 1.2 1.3 1.2 1.3 8.8 19.5 1.5 1.6 1.2 10.4 1.2 19.9 1.2 1.3 1.6 1.3 1.2 1.2 4.1 1.6 1.3 4.2 1.2 1.5 3.9 2.7 0.0 1.2 0.0 1.3 1.2 0.2 0.4 0.0 0.0 0.2 0.0 3.6 0.1 2.2 1.0 1.0 15.0 0.0 0.0 1.2 0.1 0.1 0.2 0.6 0.5 0.9 3.6 1.7 0.0 2.5 0.0 4.4 0.0 0.0 2.5 2.9 0.3 3.6 1.6 0.0 0.8 0.8 0.3 0.0 0.5 0.5 0.8 0.0 9.8 3.1 1.9 0.0 0.5 1.5 0.4 4.5 0.4 4.6 9.9 3.0 5.1 0.2 0.1 26.5 13.2 0.5 0.9 2.7 0.8 2.4 1.3 0.0 1.8 2.8 2.0 0.5 10.8 8.6 2.1 3.3 2.0 0.1 0.0 0.2 0.0 0.0 0.2 3.6 0.1 0.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 2.0 0.1 20.4 13.6 51.0 34.3 16.1 16.3 8.8 19.5 19.9 2.7 0.0 3.7 0.0 1.9 0.8 22.6 0.8 0.0 1.4 0.0 0.0 41.2 0.4 0.0 0.1 13.0 1.0 0.7 0.0 0.4 0.4 0.7 0.9 1.1 0.8 0.2 14.3 0.0 0.6 1.2 6.5 0.6 1.0 5.0 0.0 0.0 3.6 0.3 2.9 1.1 0.1 18.7 0.0 0.8 2.8 4.1 1.3 0.2 1.0 0.4 0.6 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036124 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 83.3" "Cell type enhanced" "Detected in many" 5 "Cardiomyocytes: 43.3;Cone photoreceptor cells: 51.1;Enterocytes: 45.1;Late spermatids: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "non-classical monocyte: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol NA NA Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 8.9 4.3 7.0 9.9 8.1 3.7 7.1 7.1 11.8 13.6 15.2 8.4 6.6 11.2 16.7 7.7 8.8 9.5 9.9 25.5 5.0 7.6 4.8 6.1 5.9 4.4 8.9 7.3 19.8 3.6 9.1 10.5 5.5 10.1 13.9 13.9 7.2 8.3 8.6 83.3 5.5 21.3 14.9 5.8 2.5 9.0 24.8 4.8 3.5 5.7 27.4 7.5 16.3 10.6 0.5 1.9 1.4 4.3 1.4 1.4 0.5 14.9 12.1 12.3 9.4 16.1 23.1 13.6 16.0 11.6 14.8 16.5 13.9 4.9 23.4 7.5 19.5 30.0 7.4 14.8 9.1 15.7 11.2 8.0 10.6 13.7 12.7 14.0 5.6 13.6 17.7 11.8 24.8 19.8 18.6 13.8 6.1 8.1 7.2 17.6 10.2 8.2 5.8 10.1 10.1 13.9 12.2 20.6 4.4 7.7 8.1 17.1 10.1 18.8 24.6 8.0 14.1 11.2 5.6 13.4 28.7 18.5 14.9 15.8 9.7 8.7 8.5 19.1 7.7 11.8 0.0 1.1 1.4 1.4 0.6 1.4 0.2 0.7 1.4 1.9 0.5 0.5 1.0 0.0 1.4 4.3 0.1 0.0 0.5 7.0 8.1 7.1 11.8 5.0 7.6 8.9 7.3 10.1 4.8 0.0 1.3 0.0 4.2 3.8 14.9 43.3 2.5 1.4 7.9 3.5 51.1 4.4 1.7 4.2 27.6 5.3 45.1 0.0 5.4 4.0 6.6 7.8 0.0 5.6 5.5 4.8 11.6 3.1 1.6 44.9 8.3 6.4 6.8 1.0 18.3 3.0 6.7 26.6 9.6 4.2 12.7 6.5 6.1 28.4 11.7 2.4 4.6 1.9 18.1 6.0 MAST3 KIAA0561 ENSG00000099308 "Microtubule associated serine/threonine kinase 3" O60307 19 18097793-18151692 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.5" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 21.5;Late spermatids: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035061, HPA035062" Uncertain Approved "Nuclear speckles" NA NA "Nuclear speckles" "HPA035061: AB_10670585, HPA035062: AB_10671508" "unprognostic (5.94e-3)" "unprognostic (4.75e-2)" "unprognostic (1.70e-1)" "unprognostic (1.02e-1)" "unprognostic (3.38e-1)" "prognostic favorable (2.97e-4)" "unprognostic (1.93e-1)" "unprognostic (4.63e-2)" "unprognostic (1.43e-1)" "unprognostic (3.21e-1)" "prognostic favorable (7.01e-4)" "unprognostic (2.58e-1)" "unprognostic (1.64e-3)" "unprognostic (1.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.58e-3)" "unprognostic (1.26e-3)" 4.6 3.5 20.7 8.3 36.1 12.3 1.8 1.1 72.5 3.8 5.3 19.0 0.2 9.1 3.6 4.9 2.2 4.9 3.1 2.1 19.7 9.3 3.6 6.4 4.6 9.9 13.0 33.6 4.6 14.3 7.1 7.7 2.6 13.0 2.7 4.4 0.7 4.6 4.2 2.6 6.9 8.8 3.0 7.9 11.4 3.9 2.1 12.5 1.8 2.4 0.3 9.4 3.3 2.4 4.4 10.3 23.2 9.7 5.8 8.4 3.1 3.3 5.0 2.3 10.1 6.8 5.5 5.5 3.4 2.2 2.4 3.5 5.0 4.7 8.7 5.2 3.4 2.6 1.8 3.3 1.9 1.7 7.4 4.1 4.0 5.2 7.9 5.8 2.1 13.3 6.3 5.7 3.6 1.4 3.3 1.1 6.0 4.0 5.7 2.7 6.0 4.4 7.0 2.4 7.4 6.2 12.1 2.0 6.4 1.8 1.5 3.8 6.2 4.8 2.8 2.0 1.7 3.2 4.9 4.0 3.1 3.3 13.0 1.4 6.2 8.4 8.0 6.8 11.2 2.8 0.1 4.5 9.4 8.4 5.6 6.2 4.1 4.7 3.3 2.1 4.4 3.7 6.4 23.2 5.8 9.7 10.3 5.0 3.1 20.7 36.1 1.1 72.5 19.7 9.3 13.0 33.6 13.0 12.5 6.0 10.3 7.8 0.7 0.5 3.2 1.1 7.6 0.0 3.4 8.7 2.0 0.5 3.3 2.8 9.1 1.6 20.0 0.0 9.2 1.2 2.2 0.8 2.3 12.5 6.9 0.0 2.4 7.4 21.5 24.6 3.7 7.9 5.0 6.4 6.9 0.8 6.1 8.6 6.3 8.7 0.6 0.0 1.8 0.6 2.8 1.9 0.3 9.6 8.6 0.6 MAST4 KIAA0303 ENSG00000069020 "Microtubule associated serine/threonine kinase family member 4" O15021 5 66596361-67169595 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Basal glandular cells: 428.6;Basal keratinocytes: 327.4;Glandular cells: 324.3;Suprabasal keratinocytes: 348.9;Urothelial cells: 641.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 12.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 17.8;HDLM-2: 22.6;HEL: 18.7;RT4: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000544 Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA000544: AB_1079315" "unprognostic (1.77e-2)" "unprognostic (6.24e-2)" "unprognostic (1.80e-1)" "unprognostic (4.99e-3)" "unprognostic (2.83e-2)" "prognostic favorable (5.18e-5)" "unprognostic (9.01e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-2)" "unprognostic (9.47e-2)" "unprognostic (5.03e-2)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (1.37e-2)" "unprognostic (2.63e-1)" "unprognostic (2.63e-1)" "unprognostic (3.08e-2)" 16.2 12.9 10.2 6.9 11.8 2.5 12.6 6.2 19.4 13.9 6.9 6.3 6.3 6.3 14.4 8.9 31.2 11.6 9.7 24.5 9.9 8.1 14.2 9.5 13.1 5.0 6.5 9.2 20.2 5.9 35.6 16.7 18.4 11.1 10.1 5.3 5.7 13.7 8.7 12.7 16.9 6.8 11.4 5.6 6.0 8.2 10.7 5.0 37.5 8.1 21.8 20.6 13.6 22.3 3.4 1.1 12.1 0.9 2.4 7.5 1.4 7.6 4.2 2.1 0.1 6.9 6.2 5.0 1.7 2.6 0.6 0.5 3.8 2.1 0.5 3.6 1.4 1.6 6.9 6.4 17.8 0.7 22.6 2.1 18.7 2.4 1.6 0.5 0.0 6.6 10.3 9.8 3.9 7.9 7.3 14.1 1.7 1.8 2.1 4.8 6.6 2.7 0.1 1.4 0.6 3.4 0.6 1.8 0.4 1.7 22.9 3.0 2.4 2.3 0.9 0.1 1.5 1.5 0.1 13.5 1.6 2.3 2.5 2.9 5.5 2.4 0.1 4.3 0.0 1.3 12.1 0.4 0.8 1.2 0.5 2.9 3.4 4.7 1.2 0.4 2.1 5.0 2.1 4.1 2.4 0.9 1.1 7.5 1.4 10.2 11.8 6.2 19.4 9.9 8.1 6.5 9.2 11.1 5.0 29.8 44.7 9.0 428.6 327.4 18.2 114.6 17.8 29.4 59.1 17.4 2.0 33.2 31.5 46.4 104.5 72.0 17.3 0.0 103.5 42.2 34.0 324.3 92.3 37.2 4.6 7.9 30.9 60.2 6.0 92.7 38.3 9.8 45.5 2.8 14.9 56.5 55.6 15.6 30.8 73.9 3.5 38.8 35.8 11.4 8.5 348.9 114.8 15.2 15.0 641.7 MASTL "FLJ14813, Gwl, THC2" ENSG00000120539 "Microtubule associated serine/threonine kinase like" Q96GX5 10 27154824-27186924 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027175, HPA054273" Approved Enhanced Nucleoplasm NA Yes Nucleoplasm "HPA027175: AB_1853591, HPA054273: AB_2682433" "unprognostic (4.10e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-2)" "unprognostic (3.14e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.81e-5)" "unprognostic (3.78e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (2.66e-1)" "unprognostic (1.79e-1)" 9.1 7.0 3.6 8.9 6.1 21.1 8.3 4.0 7.5 7.4 7.6 3.8 5.7 5.7 6.0 6.7 12.3 5.4 5.3 5.6 6.8 4.5 6.5 7.1 10.2 14.8 5.4 5.7 7.0 12.7 6.7 6.3 14.2 6.7 5.5 7.1 5.6 8.0 4.7 4.0 10.1 10.0 6.1 5.6 8.7 6.2 11.3 2.3 21.1 6.5 4.3 12.3 8.7 7.5 3.9 2.6 5.6 4.9 2.3 4.0 1.8 11.9 9.6 18.4 6.8 2.8 4.2 10.9 17.9 7.5 29.7 36.6 11.6 12.0 9.6 6.8 7.5 14.4 11.6 11.7 7.1 21.1 8.1 11.3 11.3 6.7 6.7 1.6 4.3 8.5 2.5 3.2 17.9 3.5 3.9 6.4 7.8 8.6 21.6 18.0 7.9 14.0 4.7 13.7 6.7 3.9 9.0 30.7 7.9 7.3 4.5 8.2 11.8 11.3 7.6 7.9 12.7 7.6 9.1 5.5 7.4 15.6 18.9 15.7 2.6 4.2 14.1 8.1 13.1 6.1 0.1 4.4 3.8 2.0 4.3 3.0 2.6 2.5 1.8 2.5 3.9 2.5 2.3 5.6 2.3 4.9 2.6 4.0 1.8 3.6 6.1 4.0 7.5 6.8 4.5 5.4 5.7 6.7 2.3 6.0 8.5 7.2 4.0 9.7 1.9 1.6 0.0 4.0 9.1 1.8 0.0 3.3 0.0 3.2 1.7 3.6 3.0 0.0 2.2 20.7 5.8 3.3 12.7 1.7 5.1 3.2 4.1 2.5 12.0 1.5 2.8 5.6 0.0 1.8 3.4 1.5 3.6 1.9 2.5 1.4 0.9 0.0 5.9 11.2 16.4 8.7 5.1 8.7 3.5 5.9 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 29.3;bone marrow: 19.1;brain: 27.4" "Group enriched" "Detected in many" 6 "granulocytes: 44.9;Hofbauer cells: 58.6;T-cells: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "gdT-cell: 19.4;NK-cell: 29.3" "Group enriched" "Detected in many" 54 "NK-cells: 29.3;T-cells: 19.4" "Cell line enhanced" "Detected in some" "HL-60: 41.6;HMC-1: 12.8;K-562: 18.5;MCF7: 13.5;NB-4: 29.0;SCLC-21H: 12.7;THP-1: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" NA NA Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favorable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 11.2 1.6 22.1 6.8 18.1 19.1 2.2 1.5 27.4 1.5 2.3 1.7 0.0 7.0 1.2 0.4 1.1 4.7 5.1 1.7 25.1 10.0 1.1 2.8 7.3 9.6 7.0 11.0 1.0 1.6 0.1 1.4 1.4 6.1 1.2 1.4 0.6 3.8 1.0 0.8 1.6 6.7 1.1 2.8 14.8 4.1 2.1 1.3 3.5 0.9 0.0 4.5 2.4 0.7 0.4 0.3 0.4 0.0 29.3 19.4 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.4 4.2 5.5 0.1 0.0 0.0 7.2 4.6 0.5 1.1 0.0 41.6 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 18.5 0.0 0.0 13.5 0.1 29.0 3.4 3.5 0.1 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.4 0.0 10.9 1.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 13.2 0.0 2.5 12.2 0.3 0.4 1.2 7.1 0.4 29.3 0.0 0.1 0.1 2.7 22.1 18.1 1.5 27.4 25.1 10.0 7.0 11.0 6.1 1.3 0.0 1.4 2.4 0.0 0.3 1.7 1.1 0.0 1.4 0.0 0.0 11.8 0.2 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.3 0.5 0.1 44.9 0.8 58.6 0.0 6.8 11.6 3.5 4.0 0.0 7.2 1.7 1.0 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.3 2.7 1.0 0.2 105.8 0.1 0.0 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.4" "Cell type enhanced" "Detected in many" 15 "Extravillous trophoblasts: 36.8;Spermatocytes: 10.2;Spermatogonia: 19.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "T-reg: 4.8" "Lineage enriched" "Detected in many" 5 "T-cells: 4.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA017214 Uncertain NA Yes "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.91e-7)" "prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 1.5 1.1 0.3 11.4 0.6 7.7 2.6 0.2 0.8 2.1 5.9 0.3 0.1 4.5 1.2 1.5 12.2 0.4 1.6 1.3 0.5 0.4 1.2 1.3 2.0 8.3 0.4 0.1 0.7 0.8 0.0 0.3 6.3 0.5 0.7 7.8 0.4 2.3 0.1 0.9 2.8 4.6 1.9 1.0 5.2 2.9 11.3 0.4 42.4 0.5 7.2 12.6 1.5 3.3 0.1 0.6 1.0 0.1 0.4 4.8 0.5 35.6 18.4 24.8 14.6 3.4 5.9 14.4 26.5 18.7 37.2 45.9 14.0 14.1 11.9 8.5 13.0 32.5 12.3 21.6 16.6 41.1 32.5 8.6 9.4 21.8 14.0 1.3 14.5 11.9 2.1 3.0 28.6 16.3 4.8 18.7 18.6 11.9 19.1 30.4 11.9 18.0 6.8 19.8 16.1 14.4 16.7 16.7 7.6 11.4 12.0 16.8 12.5 14.1 13.6 8.6 14.4 11.4 6.9 9.2 20.1 25.4 16.9 24.1 3.8 13.6 17.9 12.7 10.8 27.2 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.8 1.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.6 4.8 0.5 0.3 0.6 0.2 0.8 0.5 0.4 0.4 0.1 0.5 0.4 0.0 0.0 0.0 0.4 4.0 0.0 0.3 0.0 1.4 2.3 0.0 0.0 4.2 0.0 0.8 1.8 0.0 1.2 0.0 1.0 36.8 2.1 0.2 0.0 0.2 8.4 0.0 0.0 1.3 0.6 1.8 1.1 2.3 0.0 5.4 1.3 0.0 1.1 2.9 0.0 0.0 0.0 0.0 0.9 10.2 19.0 1.5 7.4 0.0 3.7 1.4 MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898479-112029561 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 15 "Ito cells: 36.8;Kupffer cells: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 10.3;non-classical monocyte: 6.4" "Lineage enriched" "Detected in single" 48 "monocytes: 10.3" "Cell line enhanced" "Detected in many" "CACO-2: 21.3;Hep G2: 22.1;HUVEC TERT2: 22.0;RT4: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" NA NA 29000000 "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: AB_2686759" "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favorable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" 20.1 55.1 13.1 12.5 17.8 1.9 31.8 6.2 13.8 10.8 13.8 6.8 27.7 11.5 11.3 25.4 8.4 12.8 11.7 7.1 16.5 6.3 14.2 18.9 12.7 30.3 8.1 10.1 12.9 9.0 23.9 14.3 18.4 18.6 14.1 7.9 20.4 6.8 24.9 6.4 6.4 12.8 13.6 12.2 38.4 12.3 17.3 9.8 1.7 9.9 2.0 8.4 14.1 26.6 0.0 0.2 0.1 10.3 0.0 0.0 0.3 0.5 0.9 4.4 10.0 0.2 0.1 7.1 0.0 0.1 0.5 1.0 21.3 1.3 0.1 4.7 0.0 4.6 0.1 5.8 0.0 0.8 0.8 3.1 3.8 0.0 22.1 0.1 0.1 0.9 0.2 0.0 5.1 0.3 2.3 22.0 0.8 1.2 2.0 1.7 1.0 0.0 5.0 2.7 0.6 3.4 1.4 1.2 1.7 11.2 13.1 0.1 4.2 0.1 0.3 1.7 1.6 0.0 0.2 3.3 0.6 2.0 0.0 0.0 1.7 2.5 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 6.4 0.1 0.0 0.3 13.1 17.8 6.2 13.8 16.5 6.3 8.1 10.1 18.6 9.8 3.0 20.1 0.8 2.9 1.4 0.6 2.1 5.1 1.4 11.4 0.0 2.0 2.6 1.7 0.8 1.6 7.1 1.6 0.0 0.8 1.0 4.1 2.0 0.0 8.9 23.6 0.0 0.0 36.8 92.6 1.5 4.6 11.0 0.0 0.0 2.3 8.6 1.7 1.9 6.3 1.9 9.2 6.5 11.3 0.5 1.5 1.1 15.8 0.8 1.8 1.4 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672390-116798386 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease mutation, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Alveolar cells type 2: 78.1;Club cells: 116.0;Urothelial cells: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 45.3;CAPAN-2: 49.5" "Group enriched" "Detected in many" 5 "amygdala: 3.5;basal ganglia: 9.9;cerebral cortex: 7.6;hippocampal formation: 8.0;olfactory region: 9.1" "Low region specificity" "Detected in many" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 179000000 70000000 "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 16.2 1.1 1.8 4.5 2.3 4.3 11.2 0.9 15.2 9.9 6.5 2.4 2.4 4.4 7.5 5.2 5.1 4.6 12.3 5.4 5.7 1.8 20.1 30.2 15.6 1.4 3.6 2.1 2.0 9.3 0.7 8.1 24.4 2.6 8.0 6.6 34.1 12.2 8.4 12.8 7.2 8.6 4.0 2.3 5.7 10.6 2.7 2.4 0.5 21.4 7.0 2.1 10.1 15.0 0.2 0.3 1.2 0.2 0.3 0.4 0.0 45.3 26.1 0.0 0.1 2.0 2.0 1.8 25.9 10.5 14.0 11.8 5.4 49.5 2.0 43.2 16.2 37.7 12.0 4.4 24.7 28.6 0.1 5.6 0.0 27.1 4.7 0.3 0.0 0.0 2.6 9.8 9.1 30.0 25.3 9.6 0.0 0.9 0.2 25.9 1.0 0.0 0.0 3.9 7.2 26.6 0.0 22.0 0.0 24.5 5.2 3.8 0.0 10.6 3.4 10.1 4.7 0.0 0.2 17.6 20.9 7.4 11.0 20.0 0.5 4.0 0.2 22.9 0.0 2.9 1.1 0.2 0.4 0.4 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.2 1.2 0.3 0.1 0.3 0.1 0.0 1.8 2.3 0.9 15.2 5.7 1.8 3.6 2.1 2.6 2.4 26.8 78.1 2.4 56.1 34.7 0.9 10.0 15.3 22.7 116.0 29.6 0.0 57.9 0.0 28.0 0.0 11.7 11.2 0.0 39.8 5.0 4.0 55.8 0.0 26.0 6.1 0.0 6.9 1.3 1.0 0.0 0.6 2.0 3.3 1.8 19.7 7.4 69.4 7.0 0.0 13.5 0.3 0.0 2.3 0.0 0.6 15.6 18.2 0.0 12.7 88.5 MINK1 "B55, MAP4K6, MINK, YSK2, ZC3" ENSG00000141503 "Misshapen like kinase 1" Q8N4C8 17 4833388-4898061 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056296 Approved NA NA "HPA056296: AB_2683090" "unprognostic (2.80e-1)" "unprognostic (3.83e-2)" "unprognostic (1.85e-1)" "unprognostic (6.62e-2)" "unprognostic (2.88e-1)" "unprognostic (3.26e-3)" "prognostic unfavorable (3.00e-4)" "unprognostic (4.64e-3)" "unprognostic (3.21e-1)" "unprognostic (2.78e-2)" "prognostic favorable (2.77e-4)" "prognostic unfavorable (9.27e-4)" "unprognostic (8.44e-3)" "unprognostic (2.49e-2)" "unprognostic (1.37e-1)" "unprognostic (2.47e-2)" "unprognostic (1.62e-1)" 12.7 14.8 31.4 18.2 46.8 14.9 14.2 30.8 43.5 15.2 26.0 32.6 8.8 33.1 12.4 7.7 40.0 14.3 15.6 9.0 28.4 12.8 13.8 10.0 23.3 17.1 28.6 27.3 27.5 21.5 16.5 15.4 17.4 29.0 14.3 20.7 14.5 21.1 11.3 8.3 47.3 31.1 11.4 24.8 20.0 22.3 14.5 30.9 9.0 12.7 14.6 16.8 14.9 24.1 2.6 1.2 6.4 1.6 0.3 3.0 2.3 18.8 34.5 8.0 13.1 12.8 9.3 23.2 15.0 13.8 12.0 10.1 13.1 13.1 13.4 17.4 15.8 11.9 38.2 6.0 27.1 5.9 19.3 16.8 9.6 21.9 10.2 8.4 3.5 18.8 9.9 20.3 11.3 10.5 10.2 13.0 4.5 10.3 11.7 8.8 11.2 5.7 8.1 6.3 12.3 11.2 7.2 6.7 8.1 18.4 19.3 8.4 6.7 15.6 13.0 9.8 9.2 11.7 4.9 18.7 12.8 5.8 21.7 14.3 6.7 5.4 2.7 11.5 7.7 8.6 0.0 1.6 6.4 2.7 1.6 3.0 2.6 2.8 2.1 1.2 1.5 2.0 0.8 1.3 0.3 0.8 0.8 2.8 2.3 31.4 46.8 30.8 43.5 28.4 12.8 28.6 27.3 29.0 30.9 0.0 1.3 1.9 12.1 36.5 6.4 1.4 12.7 1.4 3.4 5.2 37.3 15.1 5.0 7.8 2.6 8.8 31.0 0.0 9.0 10.5 7.3 11.7 8.1 8.1 17.6 12.7 18.0 13.5 12.1 5.4 15.0 8.8 15.1 45.1 29.6 6.5 11.9 42.1 13.8 7.5 15.5 12.9 4.4 5.0 9.4 52.9 16.4 6.9 27.3 18.7 MKNK1 MNK1 ENSG00000079277 "MAP kinase interacting serine/threonine kinase 1" Q9BUB5 1 46557408-46616843 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 72.3" "Cell type enhanced" "Detected in all" 6 "Hofbauer cells: 113.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB027355, CAB037310, HPA071293" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB027355: AB_2266303, CAB037310: AB_1854049, HPA071293: AB_2686382" "unprognostic (4.05e-3)" "prognostic favorable (7.05e-4)" "unprognostic (5.28e-2)" "unprognostic (3.47e-2)" "unprognostic (1.64e-1)" "unprognostic (7.38e-2)" "prognostic unfavorable (1.24e-5)" "unprognostic (3.50e-2)" "unprognostic (1.77e-1)" "unprognostic (2.60e-1)" "unprognostic (1.50e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (1.51e-5)" "unprognostic (7.02e-2)" "unprognostic (3.19e-2)" "unprognostic (4.67e-1)" "unprognostic (5.67e-3)" 17.6 12.0 10.7 16.2 10.5 16.8 12.1 13.7 12.3 9.2 12.6 11.0 9.6 9.7 11.9 13.3 12.2 11.1 11.4 12.3 10.8 7.0 9.4 10.8 16.1 16.3 9.9 9.8 10.7 72.3 8.6 11.3 15.4 11.0 9.9 13.3 11.9 10.6 7.7 12.8 10.2 12.7 13.3 8.1 25.6 11.7 7.6 8.7 12.5 8.8 15.8 10.9 10.9 14.5 4.9 6.0 33.3 12.1 5.0 22.0 6.1 19.5 13.2 8.8 9.7 7.9 11.7 11.7 9.9 9.9 12.0 16.4 15.3 8.0 12.9 12.2 9.9 13.5 23.7 14.7 16.2 12.9 22.2 13.0 27.3 15.2 13.0 12.3 14.6 22.2 15.4 11.2 15.6 8.6 6.5 14.0 15.9 14.2 9.5 6.5 12.8 10.4 13.0 6.0 11.3 15.7 9.6 18.4 12.9 12.9 20.5 6.2 5.5 19.1 17.3 16.0 18.3 11.7 16.3 11.4 4.4 0.9 13.6 11.0 8.1 13.5 11.0 8.5 18.8 8.0 3.9 12.1 14.3 7.5 11.5 22.0 4.6 6.6 6.8 6.0 4.9 4.8 7.0 33.3 5.0 8.1 4.4 4.4 6.1 10.7 10.5 13.7 12.3 10.8 7.0 9.9 9.8 11.0 8.7 11.9 22.1 17.5 15.7 12.4 17.9 15.5 15.3 10.7 18.2 21.0 2.0 19.4 6.6 16.1 13.0 14.3 23.5 23.3 32.1 29.7 19.5 15.8 11.5 20.2 113.5 17.5 16.1 18.4 71.2 17.5 19.8 58.2 10.1 16.2 11.9 6.5 28.0 14.0 34.3 10.2 4.6 6.5 14.4 16.8 15.5 9.7 15.4 24.9 14.7 19.5 MKNK2 "GPRK7, MNK2" ENSG00000099875 "MAP kinase interacting serine/threonine kinase 2" Q9HBH9 19 2037465-2051244 "Enzymes, Predicted intracellular proteins" "Apoptosis, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021875, CAB037253, HPA070499" Supported Supported "Nuclear bodies" No No "Nuclear bodies" "CAB037253: AB_1079401, HPA021875: AB_1854050, HPA070499: AB_2732157" "unprognostic (8.76e-2)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "prognostic favorable (4.86e-5)" "unprognostic (3.08e-1)" "unprognostic (1.59e-2)" "unprognostic (6.42e-3)" "unprognostic (1.35e-1)" "unprognostic (4.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.08e-1)" "unprognostic (6.56e-2)" "unprognostic (4.07e-2)" "prognostic favorable (4.01e-4)" "unprognostic (1.63e-1)" "unprognostic (1.60e-1)" "unprognostic (1.59e-1)" 30.3 15.6 7.6 24.2 8.5 31.9 31.1 16.6 9.7 12.5 22.7 6.5 21.4 13.1 9.3 18.4 42.1 11.0 21.7 33.3 7.5 5.7 10.3 22.0 24.5 16.9 10.3 3.3 13.8 53.1 8.3 13.4 16.7 9.2 18.8 8.4 14.2 35.2 32.5 207.5 19.3 15.1 13.0 7.0 27.8 16.7 9.1 9.1 16.0 32.3 47.1 32.8 21.2 63.6 10.7 5.9 26.9 8.0 6.1 7.5 2.2 13.4 15.1 6.4 14.1 47.8 17.4 14.4 7.9 5.7 5.7 5.8 9.7 23.5 19.0 11.0 16.0 5.9 16.6 8.1 23.2 2.6 25.8 7.5 7.7 12.7 10.3 80.4 15.0 13.8 18.4 56.5 10.8 23.0 13.3 13.5 12.8 13.1 34.0 3.9 7.8 8.9 12.5 16.8 10.2 16.5 17.2 1.8 23.9 10.1 8.7 8.9 10.6 18.7 27.6 34.0 7.5 11.4 18.6 20.2 2.1 8.2 8.4 9.5 55.3 21.4 18.5 16.8 11.3 3.8 2.7 6.1 5.7 5.6 6.3 5.1 10.7 5.8 6.2 4.8 10.2 3.7 4.5 26.9 6.1 8.0 5.9 7.5 2.2 7.6 8.5 16.6 9.7 7.5 5.7 10.3 3.3 9.2 9.1 35.7 53.3 43.1 91.9 73.3 45.8 46.4 30.6 16.0 11.4 34.9 23.6 21.3 8.3 25.3 6.2 35.4 94.0 23.3 48.2 31.0 32.0 121.4 28.8 50.0 30.9 39.7 144.2 58.3 34.6 10.0 18.7 27.4 54.0 19.8 92.4 38.7 46.8 69.1 19.1 18.2 43.0 19.4 34.0 15.5 21.8 102.4 47.3 39.5 64.3 110.6 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "vagina: 50.4" "Cell type enhanced" "Detected in many" 6 "granulocytes: 27.8;Macrophages: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 18.5 4.7 5.2 15.1 8.9 21.6 13.2 2.9 7.9 6.4 8.0 3.2 5.3 8.5 7.5 3.8 11.5 5.2 9.1 6.8 6.4 3.5 7.4 6.7 17.3 14.8 10.5 1.8 2.8 8.2 1.6 3.0 7.1 8.1 6.3 9.2 6.5 12.6 4.3 2.3 3.6 10.0 6.0 11.2 26.2 8.2 1.9 8.4 4.3 6.5 4.9 10.4 9.2 50.4 4.2 9.2 25.2 17.7 1.7 8.1 7.1 6.5 12.2 0.1 0.1 3.2 6.7 0.1 8.5 7.4 8.0 11.9 7.0 13.2 0.1 9.8 7.2 6.9 10.5 2.2 12.2 3.0 4.1 0.3 9.2 9.1 8.0 2.3 6.0 9.6 4.5 1.2 8.5 3.0 4.7 19.3 10.7 1.3 1.3 6.2 10.9 3.4 12.0 1.1 14.3 15.0 6.7 0.9 11.7 11.4 4.8 0.5 0.4 6.7 4.5 3.7 0.0 3.2 6.3 21.0 4.0 2.4 3.6 5.8 5.7 19.2 1.6 7.3 21.2 1.9 8.3 17.7 21.7 5.8 10.6 7.9 4.2 6.5 6.0 9.2 2.8 3.6 5.5 25.2 1.7 10.2 0.5 8.1 7.1 5.2 8.9 2.9 7.9 6.4 3.5 10.5 1.8 8.1 8.4 3.0 15.4 8.1 4.8 3.1 0.0 1.6 2.5 2.7 7.9 1.8 0.0 0.2 1.7 4.0 2.6 17.9 5.8 0.0 4.6 0.5 3.8 2.0 27.8 0.9 14.2 1.6 1.2 14.7 15.5 3.8 0.9 24.1 6.8 1.0 5.6 0.0 4.1 9.1 0.4 0.3 0.4 0.0 3.3 0.0 0.2 2.5 0.2 10.0 6.4 5.1 MOK "RAGE, RAGE1, STK30" ENSG00000080823 "MOK protein kinase" Q9UQ07 14 102224500-102305200 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "testis: 45.0" "Cell type enhanced" "Detected in many" 13 "Ciliated cells: 214.2;Cone photoreceptor cells: 174.7;Early spermatids: 171.0;Rod photoreceptor cells: 441.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBF TERT88: 28.6;hTEC/SVTERT24-B: 72.8;NB-4: 90.6;U-138 MG: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027292 Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA027292: AB_10600989" "unprognostic (8.16e-2)" "unprognostic (1.82e-1)" "unprognostic (6.68e-2)" "unprognostic (6.05e-3)" "unprognostic (1.34e-2)" "unprognostic (1.81e-2)" "unprognostic (4.43e-2)" "unprognostic (3.49e-4)" "unprognostic (2.19e-1)" "unprognostic (2.03e-2)" "unprognostic (2.93e-1)" "unprognostic (3.01e-3)" "unprognostic (5.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.48e-1)" 5.9 6.8 12.9 2.7 17.3 3.7 7.8 9.7 15.9 7.6 3.6 8.7 6.2 4.7 7.6 10.2 3.9 26.4 6.4 8.3 13.5 10.2 7.7 3.6 6.1 2.5 6.0 13.7 12.4 8.6 9.4 22.1 3.6 16.6 5.1 3.0 15.2 6.1 5.4 1.9 8.6 4.1 5.9 6.2 3.8 11.7 45.0 6.2 0.4 11.7 2.3 2.2 6.2 3.9 0.7 3.9 0.9 1.1 10.6 2.4 1.3 3.4 3.0 0.4 1.7 0.7 2.5 0.7 7.0 2.0 10.1 12.2 0.2 8.4 2.6 0.5 1.3 2.2 0.7 0.6 3.6 28.6 2.9 2.6 0.6 0.4 2.3 3.1 0.3 3.4 2.1 0.9 72.8 6.7 7.9 0.3 0.5 0.6 0.1 6.6 2.3 0.2 90.6 0.1 1.5 7.4 0.4 0.2 0.0 4.1 0.1 1.1 0.7 1.2 0.4 19.6 0.1 2.1 0.2 0.2 38.5 1.9 1.4 2.2 0.2 0.4 0.2 7.7 0.2 17.4 0.0 1.1 0.0 0.7 0.7 1.2 0.0 0.5 1.9 3.9 0.7 1.1 2.4 0.9 10.6 0.1 0.0 0.0 1.3 12.9 17.3 9.7 15.9 13.5 10.2 6.0 13.7 16.6 6.2 17.9 17.4 0.5 6.5 9.5 36.2 12.2 10.2 214.2 43.3 12.2 174.7 1.0 5.0 7.0 171.0 6.7 3.8 0.0 14.2 2.1 7.6 3.6 3.5 1.7 2.0 15.9 4.6 7.4 1.8 130.3 28.1 4.2 75.9 0.0 2.0 58.0 5.6 0.0 15.2 8.1 441.5 25.8 12.1 81.9 27.2 5.1 1.0 6.7 3.8 3.0 MOS ENSG00000172680 "MOS proto-oncogene, serine/threonine kinase" P00540 8 56112942-56113982 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 3.5" "Cell type enriched" "Detected in single" 8 "Early spermatids: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HAP1: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "unprognostic (3.28e-1)" 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 MST1R "CD136, CDw136, PTK8, RON" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 27.7;intestine: 34.3;skin 1: 28.7" "Cell type enhanced" "Detected in many" 7 "Alveolar cells type 1: 23.8;Enterocytes: 29.1;Mucus-secreting cells: 21.5;Pancreatic endocrine cells: 19.7;Paneth cells: 20.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "MAIT T-cell: 2.1" "Lineage enhanced" "Detected in single" "T-cells: 2.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.9;HaCaT: 19.8;HBEC3-KT: 21.6;hTCEpi: 30.3;RT4: 23.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" 1.7 0.1 0.4 7.5 0.6 0.0 2.4 0.5 0.7 1.8 20.5 0.7 2.0 11.2 1.2 1.3 6.1 0.6 27.7 0.9 0.5 0.1 1.4 0.4 5.0 1.1 0.4 0.6 0.5 4.1 0.0 1.3 0.8 0.9 1.7 9.7 2.5 2.1 0.4 0.5 28.7 34.3 0.7 0.4 0.6 19.1 1.9 0.4 7.7 1.3 6.0 4.5 4.3 3.5 0.2 0.0 0.0 0.0 0.6 2.1 0.0 12.9 5.0 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.2 35.9 0.5 3.1 0.2 0.0 19.8 0.0 21.6 0.0 0.3 0.3 0.0 8.5 0.3 0.3 0.0 0.4 0.1 30.3 0.1 4.3 0.1 0.0 0.0 0.2 0.1 0.0 1.8 0.0 0.0 0.1 11.6 10.5 0.9 0.0 0.3 13.3 23.1 0.3 0.0 3.6 8.4 0.0 0.0 6.6 0.3 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.4 0.6 0.5 0.7 0.5 0.1 0.4 0.6 0.9 0.4 23.8 10.1 0.0 2.2 7.8 0.0 1.2 0.0 2.7 9.1 0.0 0.0 0.1 0.0 5.2 13.7 0.0 29.1 0.0 8.7 0.4 0.4 1.7 0.0 0.0 0.1 0.0 4.1 0.0 0.0 7.9 0.3 0.0 0.0 1.0 21.5 0.0 19.7 20.4 0.0 0.0 0.0 0.0 0.4 1.6 0.8 4.1 0.0 0.0 12.4 4.6 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262507 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Sertoli cells: 38.8;Spermatocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol NA NA "Vesicles, Cytosol" "CAB069425: , HPA071227: AB_2686367" "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favorable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 11.3 13.9 18.7 13.0 22.5 12.3 14.9 25.2 25.2 11.3 14.5 18.2 10.4 11.2 13.8 23.6 13.1 10.5 15.7 14.2 14.5 13.6 15.8 19.4 10.8 14.3 14.0 14.4 10.7 16.6 26.5 16.0 12.5 15.5 15.2 17.1 14.4 14.2 15.2 24.6 16.5 13.6 15.2 10.4 15.4 13.1 38.6 13.1 16.6 13.2 9.9 15.7 11.7 10.2 3.9 4.0 3.0 6.4 2.6 5.6 2.3 15.2 13.9 18.7 14.2 22.7 10.8 9.4 12.9 12.4 17.3 17.0 14.2 14.1 17.0 11.1 15.2 10.7 18.2 25.3 19.8 22.4 13.5 18.5 22.6 28.7 17.9 14.2 21.9 16.8 13.8 15.1 24.7 25.1 8.2 21.8 16.4 25.2 14.6 12.0 17.4 15.1 16.8 14.2 16.0 13.1 15.2 22.1 11.4 15.3 13.9 18.9 13.9 27.6 15.0 16.9 21.5 12.2 13.0 23.3 15.1 13.7 11.5 17.3 14.4 13.4 33.4 10.9 23.8 15.9 0.7 2.9 3.0 5.2 6.4 4.3 3.9 3.0 2.7 4.0 3.4 3.6 3.1 2.0 2.6 3.3 3.1 5.6 2.3 18.7 22.5 25.2 25.2 14.5 13.6 14.0 14.4 15.5 13.1 14.9 10.2 5.2 4.5 3.1 0.0 25.7 2.5 2.7 10.3 8.7 0.0 6.5 1.7 6.3 31.2 7.8 7.9 0.0 5.4 5.9 5.1 7.5 12.7 13.0 6.1 0.0 9.9 5.5 7.3 29.3 7.2 6.0 8.5 5.4 6.8 0.0 8.6 3.5 7.8 4.3 0.0 38.8 6.9 48.4 31.3 5.0 8.2 6.5 9.5 5.5 MUSK ENSG00000030304 "Muscle associated receptor tyrosine kinase" O15146 9 110668771-110801620 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein, Kinase, Muscle protein, Receptor, Transferase, Tyrosine-protein kinase" "Congenital myasthenic syndrome, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skeletal muscle: 50.0" "Cell type enhanced" "Detected in some" 31 "Early spermatids: 2.7;Late spermatids: 3.3;Leydig cells: 4.9;Peritubular cells: 18.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "LHCN-M2: 19.8;RH-30: 20.1" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Not detected" "Not detected" NA NA "unprognostic (6.12e-2)" "unprognostic (9.01e-2)" "unprognostic (5.39e-2)" "unprognostic (3.66e-1)" "unprognostic (3.14e-1)" "unprognostic (1.20e-2)" "unprognostic (1.50e-2)" "unprognostic (2.46e-1)" "unprognostic (3.13e-1)" "unprognostic (7.58e-2)" "unprognostic (6.03e-5)" "unprognostic (4.58e-2)" "unprognostic (1.62e-1)" "unprognostic (9.67e-2)" "unprognostic (5.11e-2)" 7.5 0.3 0.6 5.8 0.7 0.0 0.2 0.1 0.2 0.3 6.8 0.0 0.0 2.3 0.2 4.0 3.8 0.1 2.1 3.2 0.9 0.7 0.2 0.5 4.2 0.9 0.2 0.1 0.3 0.3 0.0 0.2 0.6 0.3 1.9 5.3 0.0 0.4 0.0 50.0 0.3 5.0 3.0 0.3 0.2 2.6 5.9 0.0 0.0 0.3 1.4 3.9 3.6 2.9 0.0 0.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.4 0.0 0.2 0.0 20.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.2 0.9 0.7 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884331 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 191.1" "Cell type enhanced" "Detected in many" 16 "Peritubular cells: 649.2;Sertoli cells: 271.7;Smooth muscle cells: 829.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "basophil: 3.6;classical monocyte: 1.3;myeloid DC: 2.8;neutrophil: 4.5;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.8;granulocytes: 4.5;monocytes: 1.3" "Cell line enhanced" "Detected in many" "BJ: 36.4;BJ hTERT+: 55.1;fHDF/TERT166: 45.0;HBF TERT88: 29.0;hTERT-RPE1: 38.5;RPTEC TERT1: 59.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 3000000 "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 14.9 4.9 4.5 19.8 10.9 0.0 14.4 0.8 5.8 77.1 107.3 22.0 93.2 9.4 111.2 48.3 96.0 56.3 40.6 6.6 4.7 3.2 8.3 5.4 13.2 6.5 25.8 2.8 50.2 1.6 0.5 1.1 8.0 16.0 85.1 27.6 6.0 17.6 158.6 1.6 4.8 33.3 191.1 28.8 7.4 38.7 17.4 13.0 0.2 4.1 2.5 3.4 137.1 21.3 0.2 2.8 4.5 1.3 0.0 0.2 17.3 2.5 7.7 2.0 1.3 2.1 0.4 0.9 36.4 55.1 23.6 16.9 1.6 1.4 0.1 8.2 45.0 11.2 0.9 0.9 0.3 29.0 0.0 0.1 20.3 0.2 5.0 10.9 0.1 1.9 6.8 0.7 4.6 6.9 38.5 1.8 0.2 0.2 0.1 17.4 0.3 0.0 0.5 2.2 0.1 1.0 2.3 1.2 6.6 59.6 1.4 0.3 1.1 3.7 0.4 0.6 5.0 0.2 0.0 6.7 7.2 2.6 1.7 5.9 0.6 0.7 0.0 18.5 0.2 1.8 3.6 1.3 0.3 0.1 0.2 0.0 0.2 0.0 0.0 2.8 0.1 0.2 0.1 4.5 0.0 0.0 2.7 0.1 17.3 4.5 10.9 0.8 5.8 4.7 3.2 25.8 2.8 16.0 13.0 14.9 34.7 2.9 24.1 18.2 2.5 16.5 33.1 5.3 6.8 26.2 117.8 0.6 3.3 4.5 38.5 34.3 13.8 0.0 3.6 0.6 23.4 4.9 2.3 169.4 4.0 3.2 10.9 66.9 9.2 26.0 97.0 8.0 18.6 0.0 3.0 4.8 2.7 24.0 649.2 9.6 18.7 271.7 829.4 3.0 3.3 17.7 2.1 0.5 3.7 1.6 MYLK2 "KMLC, MLCK2, skMLCK" ENSG00000101306 "Myosin light chain kinase 2" Q9H1R3 20 31819308-31834689 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 176.1" "Cell type enhanced" "Detected in single" 29 "Hofbauer cells: 1.4" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 5.3;RH-30: 13.5;RPMI-8226: 10.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059704, HPA059890" Enhanced Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "HPA059704: AB_2684108, HPA059890: AB_2684153" "unprognostic (1.74e-2)" "unprognostic (1.87e-1)" "unprognostic (8.84e-2)" "unprognostic (5.27e-2)" "prognostic favorable (4.00e-4)" "unprognostic (5.58e-2)" "unprognostic (1.38e-7)" "unprognostic (2.29e-1)" "unprognostic (2.60e-3)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (7.25e-11)" "unprognostic (2.01e-1)" "unprognostic (3.15e-1)" "unprognostic (2.60e-2)" "unprognostic (2.70e-2)" 1.4 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 176.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.1 18.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.8 0.0 0.0 0.5 0.1 0.0 0.4 0.1 0.3 0.3 0.6 0.4 0.0 0.2 0.1 0.1 0.0 0.2 0.2 0.2 0.7 0.3 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 1.7 1.0 0.7 0.2 5.3 0.1 0.8 0.7 0.4 0.7 0.0 0.4 0.8 13.5 10.9 0.1 0.1 0.7 0.6 3.4 0.1 0.0 0.1 0.1 0.1 2.7 0.3 1.0 0.6 3.0 0.1 1.0 0.2 0.2 3.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46703369-46790407 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 62.2;skeletal muscle: 20.8;tongue: 31.1" "Cell type enriched" "Detected in some" 10 "Cardiomyocytes: 162.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons and medulla: 6.6" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 9.7;HEL: 29.1;K-562: 4.5;SK-BR-3: 6.1" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.8;hippocampal formation: 5.7" "Region enriched" "Detected in single" 5 "hippocampal formation: 5.2" HPA073447 Enhanced Approved Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA073447: AB_2732225" "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 0.7 0.0 1.7 0.1 0.0 0.1 0.2 0.2 0.0 3.8 0.0 0.0 0.1 3.4 2.0 0.8 0.1 62.2 1.5 1.4 0.4 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.5 0.2 6.6 1.0 0.0 0.0 1.3 0.0 20.8 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.3 0.0 0.1 31.1 1.1 0.1 0.0 1.2 0.9 2.6 0.7 1.2 0.7 0.2 0.0 0.1 0.1 0.1 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.7 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 1.6 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.0 6.1 0.2 2.9 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.0 2.5 0.7 0.6 0.6 0.4 0.4 0.7 0.5 0.5 0.3 1.2 0.7 0.7 2.6 1.2 0.5 0.9 0.3 0.2 0.7 1.7 0.1 0.2 1.5 1.4 0.1 0.4 6.6 0.3 0.0 3.5 0.0 0.7 0.0 0.5 162.4 0.0 16.0 6.8 0.0 2.0 1.4 0.0 0.0 7.4 0.0 0.0 0.0 0.2 0.4 1.4 0.6 1.1 0.0 0.4 0.0 0.0 0.6 0.0 3.2 0.6 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.9 0.2 0.0 0.2 0.0 0.0 0.2 MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2750966 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 23.6;tongue: 63.6" "Cell type enhanced" "Detected in some" 6 "Alveolar cells type 1: 3.0;Cholangiocytes: 2.5;Proximal tubular cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 6 "HEL: 12.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" 0.5 0.3 0.3 0.3 0.4 0.4 0.8 1.4 0.7 0.3 0.3 0.3 0.3 0.1 0.3 0.5 1.0 0.2 0.3 1.0 0.5 0.5 2.6 0.3 0.5 0.3 0.4 0.3 0.3 1.1 0.7 0.7 0.4 0.4 0.4 0.1 0.4 2.4 0.4 23.6 0.8 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 1.0 63.6 1.5 0.5 0.3 0.1 0.8 0.3 0.3 0.9 1.4 0.1 0.3 0.2 0.6 1.2 1.0 1.2 0.6 0.7 1.6 0.5 0.4 0.5 1.1 1.1 1.6 0.8 0.2 1.9 0.2 0.5 0.7 0.2 0.6 12.7 0.6 0.1 0.3 0.3 0.6 1.5 0.5 0.1 1.2 0.6 0.5 0.2 0.1 0.1 0.3 0.5 0.1 1.4 0.2 0.4 0.0 0.9 0.0 0.0 0.9 0.3 1.0 0.6 0.3 0.2 0.5 1.1 0.4 0.8 0.7 0.5 0.1 0.2 0.4 0.4 0.2 0.1 0.2 0.3 1.3 0.1 0.1 0.1 0.5 0.0 0.3 0.1 0.2 1.4 0.2 0.1 0.6 0.1 0.3 0.9 0.3 0.8 0.1 0.1 0.3 0.4 1.4 0.7 0.5 0.5 0.4 0.3 0.4 0.3 3.0 0.6 0.0 0.1 0.1 0.8 1.2 2.5 0.0 1.2 0.0 0.0 0.3 0.0 0.1 0.4 0.5 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.2 1.6 1.2 0.0 0.3 0.0 0.3 1.0 0.0 1.8 0.0 0.2 0.0 0.0 1.4 2.9 0.2 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.0 0.1 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934071-26212536 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 8.1;testis: 12.5" "Cell type enhanced" "Detected in some" 23 "Early spermatids: 127.9;Late spermatids: 34.5;Muller glia cells: 68.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 5.0;cerebral cortex: 1.9;hypothalamus: 1.3;pons and medulla: 5.4" "Cell type enriched" "Detected in single" 12 "naive B-cell: 1.1" "Lineage enriched" "Detected in single" 12 "B-cells: 1.1" "Cell line enhanced" "Detected in some" "AF22: 2.3;CAPAN-2: 2.2;HEK 293: 2.7;SCLC-21H: 2.5;U-2 OS: 4.4;U-698: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.8 0.7 0.4 0.3 5.0 0.5 1.5 0.3 1.9 2.1 0.6 0.1 0.7 0.4 0.3 3.2 0.9 1.1 0.3 0.3 0.5 1.3 0.9 0.2 1.0 0.3 0.2 0.0 0.5 2.1 0.2 8.1 0.2 5.4 0.5 1.1 3.8 0.2 0.6 0.3 2.2 0.6 1.0 0.4 0.3 0.9 12.5 0.8 0.0 1.3 1.4 0.9 0.5 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 1.5 0.0 0.0 1.2 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.0 0.3 1.9 0.5 1.3 0.2 0.0 5.4 0.8 0.0 0.3 0.0 0.3 1.5 0.9 0.6 0.0 0.0 4.5 0.0 0.0 0.0 1.7 0.5 127.9 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 1.7 0.0 0.0 34.5 1.1 0.0 0.0 0.0 0.2 68.5 0.3 0.0 1.1 1.4 3.4 0.0 0.0 20.0 5.8 0.9 0.0 0.0 0.0 0.1 MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 20.0;parathyroid gland: 12.6;retina: 21.6" "Cell type enhanced" "Detected in some" 20 "Cone photoreceptor cells: 80.5;Early spermatids: 23.6;Late spermatids: 18.5;Rod photoreceptor cells: 57.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "gdT-cell: 1.4;naive CD8 T-cell: 1.1" "Lineage enriched" "Detected in single" 5 "T-cells: 1.4" "Group enriched" "Detected in some" 10 "HDLM-2: 11.3;HEL: 10.4;RT4: 11.7" "Region enriched" "Detected in single" 5 "basal ganglia: 4.7" "Not detected" "Not detected" HPA045483 Approved NA NA "HPA045483: AB_2679344" "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" 0.2 0.2 0.3 0.0 0.3 0.0 0.2 0.2 0.3 0.6 0.2 0.0 4.6 0.0 0.3 20.0 0.3 0.5 0.0 0.3 0.3 0.5 8.5 0.2 0.3 0.5 0.3 0.3 0.4 2.2 12.6 1.0 0.0 0.3 0.3 0.0 21.6 1.4 1.1 0.2 0.5 0.2 0.5 0.2 0.3 0.2 4.2 0.0 0.0 2.2 0.0 0.8 4.4 0.3 0.1 0.3 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.3 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.2 0.3 0.3 0.5 0.3 0.3 0.3 0.0 0.0 0.3 0.0 0.3 0.6 2.9 0.4 0.0 0.0 0.0 3.5 80.5 0.0 11.6 0.3 23.6 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.3 18.5 0.3 0.2 0.0 0.0 0.2 1.6 0.1 0.0 0.4 0.1 57.8 0.0 0.1 0.9 0.2 0.4 0.1 0.0 0.0 0.1 NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169392857-169612629 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Ciliated cells: 85.6;Early spermatids: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA Cytosol "Nucleoplasm, Centriolar satellite" "HPA020873: AB_10671583, HPA040413: AB_10671169" "unprognostic (4.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (6.98e-2)" "unprognostic (3.10e-1)" "unprognostic (3.95e-1)" "unprognostic (3.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (4.06e-3)" "unprognostic (2.21e-1)" "prognostic favorable (1.42e-4)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.10e-2)" "unprognostic (3.46e-1)" 9.6 10.5 13.5 9.2 15.8 6.0 8.7 20.7 14.5 13.6 8.4 12.5 7.1 5.4 12.4 9.1 7.9 15.7 10.2 11.4 13.7 13.2 10.2 6.9 7.7 8.0 15.9 11.3 16.3 6.6 15.3 16.5 7.2 16.0 11.6 7.7 8.9 6.4 10.6 7.1 4.7 5.7 11.1 18.2 8.0 8.1 18.3 14.8 14.7 13.3 6.4 7.4 10.0 8.2 4.5 3.3 6.7 3.3 2.2 5.3 1.3 4.2 1.8 7.8 8.4 12.1 13.5 2.5 8.9 8.0 7.2 6.8 2.4 5.0 11.3 1.7 7.8 6.9 1.4 7.3 7.6 8.2 12.4 5.0 7.6 7.7 2.9 7.1 7.6 6.1 10.8 4.3 7.3 12.8 14.7 7.0 10.9 13.4 21.5 9.2 2.7 9.8 3.4 2.5 2.7 4.5 6.1 5.1 3.6 7.6 5.0 8.5 9.7 6.5 3.2 6.0 6.2 4.0 3.4 8.4 4.6 4.2 4.7 6.0 8.7 13.3 8.6 7.6 3.8 8.0 6.7 2.1 1.8 4.4 3.3 4.8 4.4 3.4 2.7 1.5 4.5 5.1 5.3 1.1 2.2 1.6 3.3 3.2 1.3 13.5 15.8 20.7 12.9 13.7 13.2 15.9 11.3 16.0 14.8 11.9 13.1 13.3 12.5 8.5 20.5 31.9 0.0 85.6 22.7 17.4 27.5 17.5 14.9 8.5 83.6 9.0 5.4 23.3 5.5 6.7 16.2 7.0 17.4 6.6 9.1 17.5 6.9 8.6 6.9 39.7 21.9 8.9 5.0 2.8 5.0 23.4 6.9 4.2 29.7 8.1 24.4 12.9 18.6 59.1 27.4 5.5 24.7 8.6 6.8 9.5 NEK10 FLJ32685 ENSG00000163491 "NIMA related kinase 10" Q6ZWH5 3 27110085-27369460 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 31.4" "Cell type enhanced" "Detected in many" 12 "Ciliated cells: 97.7;Cone photoreceptor cells: 82.5;Early spermatids: 98.7;Late spermatids: 45.8" "Cancer enriched" "Detected in single" 5 "breast cancer: 1.8" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 7.7;LHCN-M2: 10.6;U-2 OS: 9.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038941 Uncertain Approved Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA038941: AB_10673600" "prognostic favorable (4.20e-4)" "unprognostic (2.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.15e-2)" "unprognostic (3.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-2)" "unprognostic (2.20e-3)" "unprognostic (1.37e-1)" "unprognostic (7.67e-2)" "unprognostic (1.33e-2)" "unprognostic (1.38e-2)" "unprognostic (1.57e-3)" "unprognostic (2.14e-1)" 0.4 0.5 4.5 0.5 14.6 0.4 14.2 0.6 6.8 1.6 2.0 1.1 2.0 2.5 0.9 8.3 2.0 10.5 2.1 3.1 8.4 3.8 1.4 2.5 4.5 0.6 0.8 6.7 2.7 0.8 0.5 9.0 0.3 3.4 1.9 0.7 1.3 0.5 1.4 10.5 0.4 1.0 1.2 0.8 0.6 1.1 31.4 1.3 0.3 0.8 0.3 0.7 1.4 0.4 0.4 0.2 1.9 0.1 0.1 0.6 0.1 1.0 2.1 1.1 1.2 0.9 2.1 0.4 7.7 1.2 2.1 1.9 0.0 0.5 0.7 1.9 3.2 1.5 0.1 0.5 0.5 2.3 1.4 0.8 0.2 4.1 3.7 0.2 0.4 1.0 2.5 0.5 3.3 0.1 2.7 1.5 4.4 0.1 0.7 10.6 0.1 0.8 0.5 0.7 0.2 0.3 1.0 0.4 0.3 4.1 0.6 0.2 0.2 1.2 0.5 0.6 0.8 6.2 0.4 0.9 5.7 9.0 0.3 0.8 0.3 0.2 0.5 4.8 0.9 2.1 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.5 0.4 0.0 0.4 0.1 0.5 1.9 0.1 0.0 0.2 0.0 0.1 4.5 14.6 0.6 6.8 8.4 3.8 0.8 6.7 3.4 1.3 6.0 0.0 0.0 0.2 0.2 4.0 10.2 2.5 97.7 13.6 1.8 82.5 0.0 0.0 0.3 98.7 0.7 0.7 0.0 0.0 0.2 2.9 1.5 0.0 0.5 0.2 0.0 0.0 0.6 1.3 45.8 1.7 0.4 0.0 0.0 0.1 1.4 0.2 0.6 1.1 0.0 19.6 0.0 1.1 25.4 1.7 0.4 0.0 0.0 0.1 0.1 NEK11 FLJ23495 ENSG00000114670 "NIMA related kinase 11" Q8NG66 3 131026850-131350465 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.9" "Cell type enhanced" "Detected in many" 14 "Ciliated cells: 148.5;Early spermatids: 122.2;Late spermatids: 80.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016908 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA016908: AB_1854364" "unprognostic (9.15e-3)" "prognostic favorable (7.10e-4)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (4.85e-3)" "unprognostic (2.48e-5)" "unprognostic (5.38e-2)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "prognostic favorable (5.92e-6)" "unprognostic (2.46e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" 3.9 5.8 9.3 2.7 11.1 0.5 8.7 2.7 7.6 7.3 2.8 11.2 8.4 2.0 6.5 16.0 3.2 26.9 6.0 2.9 9.1 10.0 8.2 1.1 5.5 1.7 7.8 5.4 8.7 2.8 5.0 9.3 4.6 17.3 4.0 3.3 3.0 3.8 6.7 1.7 2.8 2.6 4.3 7.3 1.8 2.3 17.8 5.5 0.2 12.3 2.5 1.7 4.2 3.0 0.9 1.0 1.1 1.3 0.3 2.9 0.3 5.9 2.4 1.8 5.2 7.0 10.5 1.0 2.9 5.5 4.5 3.4 2.2 8.3 0.3 2.1 5.2 4.3 3.3 0.5 5.1 6.3 0.6 0.7 0.8 0.4 1.0 2.3 0.6 1.5 4.4 8.5 4.8 2.2 4.8 0.9 2.6 0.2 0.9 7.5 4.2 0.1 0.5 0.5 0.9 2.3 0.0 0.2 0.1 10.3 2.3 2.2 2.5 1.4 0.1 2.0 0.8 4.9 0.1 0.9 4.7 2.3 3.6 1.4 1.4 2.3 0.1 3.2 0.2 0.8 0.0 0.3 1.1 0.6 1.3 1.2 0.9 2.9 2.6 0.5 0.6 1.0 0.8 0.9 0.3 0.9 1.0 1.5 0.3 9.3 11.1 2.7 7.6 9.1 10.0 7.8 5.4 17.3 5.5 14.9 2.7 0.0 3.4 3.8 2.7 1.1 2.5 148.5 29.6 1.8 5.9 0.5 5.0 4.7 122.2 2.4 1.7 0.0 2.2 1.0 5.4 1.4 0.0 0.0 1.8 0.0 2.4 2.5 0.0 80.8 6.4 1.4 0.0 1.0 2.7 5.7 2.9 3.7 5.6 8.4 6.9 6.5 2.2 30.5 4.9 1.8 1.4 0.0 1.7 1.8 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.0;testis: 41.0" "Cell type enhanced" "Detected in many" 22 "Early spermatids: 44.4;Erythroid cells: 93.5;Spermatocytes: 191.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 3.2" "Not detected" "Not detected" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: AB_2685393" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (9.47e-6)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 1.1 0.7 0.6 6.7 0.5 7.4 1.3 0.3 0.9 0.9 2.5 0.3 0.3 3.4 0.3 1.2 4.2 0.7 1.4 0.9 1.0 0.3 0.6 0.6 1.0 3.9 0.3 0.3 0.6 0.3 0.0 0.3 1.2 0.4 0.9 3.6 0.4 1.0 0.3 0.3 1.8 3.0 0.6 0.6 1.6 1.1 41.0 0.4 14.0 0.3 1.5 4.8 0.6 1.6 1.8 0.9 2.7 0.5 3.9 4.3 0.9 30.7 22.2 17.0 12.2 1.0 1.7 18.8 11.9 11.2 21.0 18.1 11.8 30.3 16.4 5.7 9.2 13.3 16.5 14.8 8.9 26.5 25.0 12.3 7.8 19.4 15.9 0.1 15.4 10.7 0.5 1.1 16.1 17.4 5.1 13.5 16.7 21.4 28.8 21.0 8.6 16.8 10.4 16.1 19.9 11.4 16.6 26.1 24.9 7.3 8.8 15.4 17.1 17.2 19.2 14.9 15.2 29.6 9.2 7.0 10.5 20.8 20.6 31.9 11.9 22.0 21.7 9.1 11.9 17.4 2.7 0.5 0.4 0.5 0.3 0.2 1.5 0.6 0.3 0.1 1.8 1.1 0.7 2.4 3.9 0.4 0.9 4.3 0.9 0.6 0.5 0.3 0.9 1.0 0.3 0.3 0.3 0.4 0.4 0.0 0.3 0.8 0.5 2.6 0.7 0.4 0.0 2.7 3.4 0.0 0.0 0.9 0.0 0.1 44.4 0.1 1.1 93.5 0.2 11.4 0.2 0.3 0.0 0.0 4.7 3.2 0.0 2.5 2.8 28.5 2.3 1.1 0.0 0.0 1.2 0.8 0.0 0.8 0.7 0.0 1.9 6.5 0.0 191.1 25.4 1.5 1.1 0.7 2.3 0.9 NEK3 "HSPK36, MGC29949" ENSG00000136098 "NIMA related kinase 3" P51956 13 52132639-52159861 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatocytes: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019062, HPA043230" Enhanced Approved Microtubules NA NA Microtubules "HPA019062: AB_2670037, HPA043230: AB_2678374" "unprognostic (8.97e-2)" "unprognostic (2.54e-2)" "unprognostic (8.12e-2)" "unprognostic (1.84e-1)" "unprognostic (2.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (4.30e-3)" "unprognostic (1.16e-3)" "unprognostic (1.70e-2)" "unprognostic (1.17e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (4.15e-2)" "unprognostic (5.34e-2)" 7.7 2.8 7.1 5.4 12.9 7.1 7.3 3.2 7.1 7.0 13.8 20.4 3.1 7.8 9.1 5.8 3.9 6.0 6.4 5.0 8.7 5.2 6.1 5.7 7.2 4.2 14.0 9.5 7.9 6.4 2.2 3.7 14.8 11.3 5.4 15.0 6.8 5.2 5.0 4.1 5.4 11.7 7.3 9.6 3.9 4.6 14.7 13.3 2.4 5.0 2.7 4.3 6.5 6.0 4.4 7.8 5.9 7.7 2.0 3.5 1.6 0.2 1.4 13.2 7.5 4.2 6.6 0.2 4.2 4.3 5.1 5.7 5.1 7.3 0.0 0.2 5.3 4.2 0.9 0.2 3.2 3.1 8.7 6.9 1.0 1.4 13.7 5.4 12.7 6.8 4.8 5.9 2.6 12.2 3.7 7.8 0.6 1.8 4.4 5.2 3.6 0.6 15.3 12.9 2.7 0.3 0.3 1.1 4.8 7.3 1.3 1.3 9.1 1.9 4.0 8.9 13.0 1.7 16.3 6.7 0.7 4.3 4.0 4.5 4.7 1.6 8.8 1.1 5.0 7.2 5.9 7.7 5.3 2.1 6.6 1.3 4.4 2.5 1.3 7.8 2.5 1.7 0.6 0.5 2.0 1.5 6.9 3.5 1.6 7.1 12.9 3.2 7.1 8.7 5.2 14.0 9.5 11.3 13.3 6.0 6.2 1.9 3.8 2.5 2.2 6.1 7.6 8.1 7.9 7.0 0.0 10.1 11.6 5.4 6.3 21.2 18.6 0.0 15.1 12.1 7.0 4.2 9.3 6.2 15.3 3.2 5.8 20.9 9.9 2.7 6.6 7.9 11.8 34.3 14.6 3.7 11.3 14.0 6.3 5.0 5.8 0.0 7.6 40.9 27.9 3.0 4.0 1.3 17.2 4.8 NEK4 "NRK2, pp12301, STK2" ENSG00000114904 "NIMA related kinase 4" P51957 3 52708449-52770949 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.7" "Cell type enhanced" "Detected in many" 6 "Spermatocytes: 58.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015750, HPA058543" Enhanced Supported Cytosol NA NA Cytosol "HPA015750: AB_1854367, HPA058543: AB_2732623" "unprognostic (1.32e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.69e-5)" "unprognostic (9.65e-3)" "unprognostic (3.42e-1)" "unprognostic (6.64e-2)" "unprognostic (8.75e-3)" "unprognostic (2.27e-1)" "unprognostic (7.85e-2)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (3.74e-3)" "unprognostic (5.11e-2)" "unprognostic (2.85e-1)" "unprognostic (1.51e-2)" "unprognostic (8.39e-2)" 7.2 10.7 15.5 9.1 15.7 7.3 11.0 20.2 16.1 10.6 8.4 10.6 9.6 7.6 10.3 10.7 8.1 15.8 7.5 7.4 12.5 14.2 11.6 12.4 7.7 8.8 12.7 8.6 15.8 10.2 13.4 17.6 8.7 11.9 9.4 9.7 9.1 8.5 11.3 10.8 5.3 6.6 9.5 10.7 7.9 11.0 47.7 12.4 11.1 15.5 5.0 10.4 9.3 10.7 5.1 6.4 12.4 11.8 4.6 5.2 5.5 12.9 10.1 13.9 10.9 12.7 9.2 15.1 9.2 12.5 17.3 17.5 8.8 9.7 13.3 4.3 9.0 19.1 6.1 16.9 10.9 23.2 13.3 7.1 10.4 12.3 11.2 7.9 25.4 10.5 5.6 10.1 22.1 14.8 9.2 6.4 11.7 12.9 10.9 10.9 11.1 13.7 9.3 12.0 13.7 10.0 12.0 12.1 9.8 9.8 18.7 10.3 6.1 19.4 11.9 9.1 11.2 11.1 15.3 5.9 11.6 11.8 18.5 17.0 12.2 17.7 13.1 13.3 12.0 12.5 12.4 11.8 5.8 4.6 7.3 5.2 3.6 4.0 4.8 6.4 5.1 4.9 4.2 1.8 4.6 4.8 3.2 3.1 5.5 15.5 15.7 20.2 16.1 12.5 14.2 12.7 8.6 11.9 12.4 11.9 5.1 9.5 4.6 3.7 12.7 3.5 0.0 21.4 15.9 5.2 11.8 6.1 8.3 6.4 16.2 5.3 5.1 0.0 8.4 6.8 4.6 6.5 7.0 13.4 7.2 6.4 4.6 4.9 14.9 16.1 13.6 7.0 1.7 5.4 9.6 16.2 7.8 0.0 11.7 14.6 17.4 6.5 5.9 58.3 31.9 3.6 5.6 5.3 8.2 4.1 NEK5 ENSG00000197168 "NIMA related kinase 5" Q6P3R8 13 52033611-52129078 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 11.8;fallopian tube: 12.7;testis: 15.7" "Cell type enriched" "Detected in many" 4 "Ciliated cells: 172.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "JURKAT: 3.5;OE19: 6.4;T-47d: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035565, HPA041399" Enhanced NA NA "HPA035565: AB_10672095, HPA041399: AB_2677453" "unprognostic (4.14e-2)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (5.80e-3)" "unprognostic (2.80e-2)" "unprognostic (2.47e-1)" "unprognostic (3.57e-2)" "unprognostic (6.50e-2)" "unprognostic (8.82e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.94e-1)" "unprognostic (2.06e-3)" "unprognostic (1.83e-3)" "unprognostic (1.10e-1)" "unprognostic (1.19e-3)" "unprognostic (9.44e-3)" 0.6 0.3 3.2 1.4 3.2 0.7 0.9 0.4 2.6 0.9 0.4 5.4 0.3 0.5 2.5 3.0 0.4 12.7 0.5 1.3 3.2 1.6 0.9 0.3 4.9 0.5 0.7 1.3 2.8 0.5 0.9 5.3 0.8 11.8 1.5 0.4 0.3 0.5 0.3 0.6 0.5 0.4 0.5 0.9 0.4 0.3 15.7 2.1 0.0 0.7 0.0 0.3 0.4 0.4 0.9 1.1 2.5 0.5 0.6 0.4 0.0 0.4 0.5 0.3 1.7 0.2 1.1 2.2 0.0 0.0 0.0 0.2 0.1 1.1 0.5 0.2 0.0 0.1 0.4 0.2 0.4 0.0 0.1 0.3 0.6 0.6 0.4 0.3 1.1 1.3 0.3 0.8 0.1 0.6 0.4 0.2 3.5 1.2 0.8 0.0 1.3 0.6 0.8 0.5 6.4 0.6 0.2 0.1 0.0 1.9 0.5 0.6 0.8 0.4 0.0 1.0 1.0 3.3 1.3 0.4 0.2 0.2 0.2 0.2 0.3 0.2 0.3 0.1 0.2 0.3 2.5 0.5 0.1 0.3 0.3 0.4 0.5 0.2 0.2 0.1 0.9 0.3 0.3 0.9 0.6 0.1 1.1 0.2 0.0 3.2 3.2 0.4 2.6 3.2 1.6 0.7 1.3 11.8 2.1 0.0 1.3 2.2 1.7 0.0 8.0 1.6 2.5 172.6 21.6 7.0 13.7 2.2 1.7 1.1 43.0 1.7 0.8 0.0 2.6 1.5 1.1 3.2 2.3 0.9 1.0 12.7 1.7 0.6 0.0 24.4 2.0 0.8 0.0 1.0 0.3 2.4 0.7 0.0 2.1 1.0 11.4 6.5 0.3 21.1 12.0 0.1 1.6 0.0 1.0 0.8 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Extravillous trophoblasts: 103.8;Hofbauer cells: 99.7;monocytes: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Nucleoplasm, Cytosol" "Centriolar satellite" "CAB045993: AB_2150651, HPA056828: AB_2683250" "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 14.8 5.3 26.1 22.2 29.1 12.8 18.8 7.2 21.2 20.5 15.6 13.4 4.3 12.5 9.2 7.5 6.8 8.5 18.4 7.0 17.1 16.6 12.9 51.9 17.0 18.1 19.4 13.3 11.2 20.5 1.6 6.4 21.4 14.7 14.8 16.6 18.5 16.9 13.2 5.5 5.1 18.2 23.4 13.0 11.3 19.0 5.8 12.9 4.0 6.3 1.9 22.0 17.7 10.1 21.9 11.5 29.0 18.8 8.3 3.8 7.6 7.4 12.3 11.9 4.6 22.5 29.4 14.8 9.4 15.1 14.6 12.2 11.6 14.0 9.1 15.1 18.1 33.4 1.4 6.1 27.3 9.9 10.0 5.4 24.9 10.4 20.4 26.9 4.5 62.6 39.1 4.4 13.8 14.3 38.4 15.9 4.3 4.4 0.4 26.0 7.8 0.2 4.9 3.0 39.4 11.2 9.6 8.9 4.6 15.6 2.7 5.3 1.8 3.0 5.8 13.3 12.6 12.7 18.4 31.0 10.7 10.8 7.3 6.4 2.0 2.5 5.2 13.4 10.2 14.1 10.2 18.8 29.0 3.8 12.3 2.4 21.9 2.3 3.2 11.5 9.0 0.4 1.6 23.4 8.3 14.7 10.6 2.8 7.6 26.1 29.1 7.2 21.2 17.1 16.6 19.4 13.3 14.7 12.9 8.9 6.6 9.8 11.0 2.2 0.7 2.5 17.8 1.4 4.5 3.5 0.0 33.9 1.7 35.3 14.7 5.5 12.9 23.3 20.0 103.8 9.9 17.8 21.9 33.3 99.7 0.0 5.8 4.3 10.7 12.3 4.6 30.4 6.8 90.2 15.5 28.1 24.3 15.2 3.5 29.9 1.8 0.0 5.3 1.2 10.6 1.0 30.2 0.0 18.6 8.9 NEK7 ENSG00000151414 "NIMA related kinase 7" Q8TDX7 1 198156963-198322420 "Enzymes, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 6 "Cardiomyocytes: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 85.5;fHDF/TERT166: 115.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015520, HPA018193" Approved Supported Nucleoplasm Yes No Nucleoplasm "HPA015520: AB_1854371, HPA018193: AB_1854372" "unprognostic (2.08e-1)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (5.38e-2)" "unprognostic (4.26e-2)" "unprognostic (3.00e-2)" "unprognostic (2.14e-2)" "unprognostic (5.47e-2)" "unprognostic (4.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.46e-3)" "unprognostic (2.82e-1)" "unprognostic (1.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-2)" "unprognostic (1.56e-1)" 31.7 31.4 24.9 15.2 23.0 5.6 23.7 7.8 15.6 19.3 20.6 25.5 13.7 11.3 24.5 11.4 18.7 12.8 15.1 74.7 23.9 20.4 16.1 16.0 22.3 14.9 26.8 13.4 17.2 11.1 14.6 17.6 40.5 18.0 20.0 13.2 11.8 13.5 21.3 29.9 10.6 15.8 30.9 34.9 16.4 11.7 9.5 22.6 18.0 14.9 12.8 12.5 27.4 20.7 1.6 2.1 6.1 2.2 3.8 14.7 1.4 7.1 1.9 2.3 0.9 6.0 6.9 2.7 85.5 35.8 34.8 16.5 3.5 7.1 2.6 6.2 115.4 2.0 4.4 3.5 4.6 35.2 8.1 5.0 3.5 8.2 1.4 7.2 5.9 7.3 4.3 4.0 22.9 6.9 13.0 6.6 21.6 2.7 6.4 15.9 2.2 5.1 3.5 1.2 5.7 1.4 2.7 5.7 4.5 5.9 3.7 1.4 2.7 14.2 8.2 9.5 3.4 6.0 5.4 14.5 9.8 8.3 28.0 8.9 4.5 4.1 1.7 4.2 5.4 7.5 1.9 2.2 3.0 3.2 1.9 14.7 1.3 3.6 4.6 2.1 1.6 2.9 3.6 6.1 3.8 1.7 1.4 6.0 1.4 24.9 23.0 7.8 15.6 23.9 20.4 26.8 13.4 18.0 22.6 26.8 24.2 12.3 15.3 45.6 9.4 150.0 10.2 25.4 21.6 17.4 13.7 11.6 10.0 8.8 2.1 26.3 19.8 46.7 16.9 13.3 24.9 20.4 8.1 19.2 15.2 3.2 19.0 35.0 42.5 1.7 27.0 23.7 28.7 16.2 19.6 10.0 34.6 17.3 36.0 11.6 25.0 19.4 44.2 7.5 5.7 43.0 53.8 20.1 14.9 22.4 NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease mutation, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "plasmacytoid DC: 14.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040661, HPA040679" Approved NA NA "HPA040661: AB_10794065, HPA040679: AB_10796226" "unprognostic (2.63e-1)" "unprognostic (4.57e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (6.25e-2)" "unprognostic (2.23e-2)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "prognostic favorable (4.52e-4)" "unprognostic (7.85e-2)" "unprognostic (1.37e-1)" "unprognostic (1.51e-3)" "unprognostic (1.55e-1)" "unprognostic (4.87e-3)" "unprognostic (4.61e-2)" "unprognostic (3.58e-1)" "unprognostic (1.75e-1)" "unprognostic (4.67e-3)" 3.5 4.6 2.9 11.9 4.5 2.0 4.3 1.7 4.9 5.3 4.0 4.7 1.4 4.2 2.1 5.0 4.8 5.9 4.4 1.6 2.9 1.9 10.4 6.9 5.7 7.8 2.3 2.1 4.4 6.4 8.5 9.7 8.7 5.6 5.6 3.2 5.2 5.3 4.1 0.9 4.4 6.5 1.7 3.0 8.4 4.9 4.9 1.4 4.8 10.7 3.5 15.6 4.5 3.0 4.7 14.7 3.2 1.0 1.3 1.1 0.8 2.2 3.5 3.8 3.0 2.1 2.3 11.6 1.0 2.2 1.4 1.8 5.6 5.2 13.5 3.8 2.9 2.6 3.9 5.5 5.0 1.4 3.5 6.8 3.0 5.7 10.2 3.6 1.9 4.0 5.2 1.9 2.6 6.2 2.0 1.0 2.0 4.4 1.4 1.5 4.8 1.8 3.5 3.5 3.8 1.1 4.9 2.4 6.0 7.5 5.9 6.8 1.6 3.2 6.6 1.6 5.2 9.9 2.5 0.9 1.3 2.5 1.7 1.0 1.6 1.8 9.1 2.2 1.7 3.2 3.2 0.9 1.2 0.8 0.4 0.9 3.0 0.7 0.7 0.1 4.7 0.8 1.1 0.5 1.3 1.0 14.7 0.5 0.8 2.9 4.5 1.7 4.9 2.9 1.9 2.3 2.1 5.6 1.4 8.9 17.1 11.5 7.4 2.5 2.6 1.6 5.1 10.7 13.6 24.4 7.9 14.3 6.6 4.7 7.6 2.1 10.7 0.0 5.3 8.0 4.1 6.9 25.5 4.9 3.3 1.6 9.9 4.3 3.3 1.5 3.1 4.0 3.3 3.6 10.2 1.7 3.7 13.3 2.5 3.0 1.6 0.0 1.2 4.8 5.1 1.4 9.3 4.6 12.4 3.4 NEK9 "DKFZp434D0935, MGC16714, Nek8, NERCC" ENSG00000119638 "NIMA related kinase 9" Q8TD19 14 75079353-75127344 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001405 Approved Approved Mitochondria NA NA 190000 Mitochondria "HPA001405: AB_1079467" "unprognostic (1.00e-1)" "unprognostic (5.37e-2)" "unprognostic (9.97e-3)" "unprognostic (2.64e-2)" "unprognostic (3.86e-1)" "unprognostic (2.77e-1)" "unprognostic (1.12e-1)" "unprognostic (5.60e-3)" "unprognostic (2.81e-1)" "unprognostic (1.15e-1)" "prognostic favorable (5.63e-4)" "unprognostic (8.58e-2)" "unprognostic (1.36e-2)" "unprognostic (4.54e-2)" "unprognostic (9.22e-2)" "unprognostic (2.61e-1)" "unprognostic (1.57e-2)" 17.0 20.4 12.7 17.7 17.4 7.3 15.1 15.4 13.3 18.6 18.7 18.3 23.5 14.0 25.0 13.8 15.6 20.0 15.9 23.5 11.4 8.7 14.0 13.3 12.9 16.2 20.2 10.6 25.6 15.7 24.7 23.6 14.3 13.0 15.3 8.1 15.4 12.4 18.9 36.2 10.6 15.3 24.7 14.5 14.7 14.8 16.6 18.2 21.5 17.0 14.1 14.4 23.6 18.7 6.0 6.4 7.5 5.4 5.5 6.2 3.1 10.1 12.0 15.2 17.0 19.6 26.9 17.4 16.5 11.7 8.1 7.9 10.1 8.9 17.5 0.1 11.3 6.7 14.0 11.6 6.4 9.0 14.2 6.7 8.5 12.0 7.3 12.8 5.1 11.4 18.3 7.6 8.4 6.4 21.5 10.1 12.1 9.6 11.3 9.7 1.1 10.8 5.2 9.0 12.9 6.1 17.5 19.4 9.0 6.1 12.5 7.4 18.7 13.3 6.4 12.8 16.7 15.9 14.8 15.3 12.3 5.2 14.3 6.4 18.3 19.5 17.6 9.0 8.7 8.3 7.5 5.4 5.8 4.2 5.0 5.9 2.8 4.8 3.9 6.4 6.0 6.2 5.9 5.5 5.5 3.5 1.8 2.6 3.1 12.7 17.4 15.4 13.3 11.4 8.7 20.2 10.6 13.0 18.2 11.9 33.3 10.4 7.4 7.8 16.5 47.6 5.1 14.7 19.4 10.4 33.4 13.4 6.6 5.0 9.2 14.3 10.6 0.0 4.3 13.7 11.8 6.1 15.1 28.4 12.0 12.7 5.2 17.8 18.7 6.4 23.0 12.6 3.3 6.4 10.5 12.1 5.0 9.0 24.8 7.8 22.6 0.0 12.3 23.8 12.8 8.9 11.7 10.0 10.6 4.8 NIM1K "MGC42105, NIM1" ENSG00000177453 "NIM1 serine/threonine protein kinase" Q8IY84 5 43192071-43280850 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 23.7;pituitary gland: 9.7" "Cell type enhanced" "Detected in some" 16 "Bipolar cells: 7.1;Cone photoreceptor cells: 5.9;Horizontal cells: 17.5;Muller glia cells: 8.2;Rod photoreceptor cells: 6.1" "Cancer enriched" "Detected in some" 11 "glioma: 6.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-reg: 3.2" "Group enriched" "Detected in many" 10 "dendritic cells: 1.2;T-cells: 3.2" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 4.5;HDLM-2: 4.9;PC-3: 5.6;U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007695 Uncertain Approved Cytosol NA NA Cytosol "HPA007695: AB_2667897" "unprognostic (7.97e-2)" "unprognostic (9.79e-2)" "unprognostic (8.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (4.35e-2)" "unprognostic (1.35e-1)" "unprognostic (4.28e-2)" "unprognostic (8.84e-4)" "unprognostic (1.25e-1)" "unprognostic (1.55e-5)" "unprognostic (2.18e-1)" "unprognostic (2.66e-1)" "unprognostic (6.46e-3)" "unprognostic (4.98e-3)" 1.4 3.5 9.4 1.6 10.9 0.9 1.3 4.9 23.7 1.6 1.4 6.3 0.0 1.1 1.2 1.6 1.6 1.4 1.5 1.8 8.7 7.7 1.4 1.2 3.6 1.2 5.6 5.8 1.2 1.5 1.2 9.7 1.8 6.4 1.4 1.7 1.7 2.3 2.4 2.0 1.8 1.2 1.3 4.9 1.0 3.0 1.4 8.1 0.0 2.7 0.0 1.0 1.1 0.8 0.1 1.2 0.0 0.0 0.2 3.2 0.0 0.2 0.6 0.1 0.1 0.9 0.6 0.0 1.0 3.2 1.2 4.5 0.1 0.0 0.5 0.6 0.8 1.6 0.3 0.6 0.0 2.8 4.9 0.3 0.1 0.6 0.2 1.6 0.2 0.7 1.9 0.1 0.5 0.0 1.7 0.0 0.1 0.2 0.3 0.9 0.2 0.3 0.2 0.0 0.0 5.6 0.2 0.3 0.5 0.1 0.7 0.9 0.1 1.8 0.5 0.3 0.2 0.4 1.5 0.0 0.9 0.8 0.8 0.7 1.6 0.4 0.3 6.1 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.2 3.2 0.0 9.4 10.9 4.9 11.6 8.7 7.7 5.6 5.8 6.4 8.1 0.0 4.1 0.0 0.1 0.5 7.1 0.3 0.0 0.0 0.0 0.0 5.9 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.3 0.1 0.0 0.0 0.1 17.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.0 8.2 0.2 0.0 0.7 0.0 6.1 0.0 0.4 0.4 0.5 0.4 0.0 0.0 0.0 0.0 NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Bipolar cells: 93.3;Cone photoreceptor cells: 145.3;Early spermatids: 243.8;Late spermatids: 250.1;Rod photoreceptor cells: 92.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 32 "basophil: 17.6" "Lineage enriched" "Detected in single" 32 "granulocytes: 17.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018192, HPA056511" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: AB_1854525, HPA056511: AB_2683160" "unprognostic (7.19e-2)" "unprognostic (1.98e-1)" "unprognostic (5.54e-2)" "unprognostic (5.64e-3)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (2.59e-3)" "unprognostic (2.72e-2)" "unprognostic (4.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (5.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.92e-1)" "unprognostic (5.27e-2)" "unprognostic (6.57e-2)" 6.4 30.5 19.4 10.9 14.1 7.4 7.5 7.5 38.2 6.2 6.7 8.3 14.4 8.3 5.7 8.8 4.5 5.1 8.2 8.5 18.2 12.0 13.0 8.2 7.1 11.7 15.2 23.6 4.6 11.5 20.8 9.4 9.1 7.0 6.7 7.1 12.7 5.8 17.4 4.9 4.5 8.3 4.6 15.3 10.1 7.0 17.4 7.5 10.9 13.2 3.7 11.0 7.2 4.4 0.5 0.3 17.6 0.3 0.1 0.5 0.2 4.6 5.4 13.0 4.5 2.8 3.6 5.8 4.7 4.8 7.8 6.0 27.1 4.2 6.3 7.1 3.8 9.9 4.4 9.2 8.5 9.0 14.6 5.8 24.8 5.0 4.6 4.7 5.2 25.6 4.7 5.3 5.1 6.2 7.6 9.1 18.0 9.5 7.7 7.1 5.5 13.4 6.0 5.0 9.1 2.7 11.2 8.4 4.6 14.2 5.7 9.5 3.6 7.1 6.8 29.1 16.4 10.6 8.3 9.3 5.6 7.6 4.6 9.4 9.0 8.6 6.1 5.5 5.7 6.1 17.6 0.2 0.2 0.3 0.3 0.1 0.5 0.4 0.4 0.2 0.3 0.2 0.5 0.1 0.1 0.3 0.3 0.4 0.2 19.4 14.1 7.5 38.2 18.2 12.0 15.2 23.6 7.0 7.5 20.8 5.9 4.7 3.5 4.7 93.3 23.0 10.2 6.7 4.5 31.4 145.3 2.5 1.7 3.3 243.8 10.6 5.9 0.0 5.5 3.0 3.7 5.4 24.2 8.9 7.2 35.0 27.1 10.4 14.2 250.1 5.2 5.0 15.1 4.6 9.4 9.4 5.7 7.0 2.5 6.3 92.4 12.9 3.9 25.8 9.5 4.3 5.4 5.1 8.3 5.8 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678637-153693992 "Enzymes, FDA approved drug targets, Predicted membrane proteins" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 98.4" "Cell type enriched" "Detected in many" 10 "Ito cells: 136.2" "Cancer enhanced" "Detected in all" "ovarian cancer: 39.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "ASC diff: 60.5" "Region enriched" "Detected in many" 5 "olfactory region: 23.0" "Region enhanced" "Detected in single" "olfactory region: 11.1" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 41.1 4.3 0.5 5.9 0.9 0.1 98.4 0.5 0.8 8.1 8.2 0.3 7.3 1.2 16.8 11.1 8.7 25.0 9.3 19.6 0.9 0.5 28.7 3.7 34.8 8.6 0.7 0.0 19.5 4.2 7.8 4.5 11.8 2.5 4.9 1.5 2.0 2.0 9.0 6.9 3.4 4.6 15.6 2.2 1.2 5.0 6.4 0.2 0.8 7.6 5.1 1.1 11.6 26.5 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 60.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 10.0 0.0 7.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.7 0.0 0.0 0.8 0.0 0.0 0.0 0.6 0.0 2.0 0.4 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.5 0.8 0.9 0.5 0.7 0.0 2.5 0.2 0.0 5.8 0.0 0.4 1.3 0.0 4.8 5.1 0.0 0.0 14.0 0.0 0.1 0.0 0.6 8.0 14.2 0.0 0.0 0.0 0.9 3.9 0.4 0.0 1.5 0.2 0.0 0.0 136.2 6.0 7.9 9.5 0.0 0.0 9.0 0.0 0.0 0.7 0.0 3.9 2.8 0.0 0.0 0.9 0.2 0.1 0.9 0.6 0.0 0.0 0.0 NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35792154-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease mutation, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Cell type enhanced" "Detected in many" 5 "Leydig cells: 8.6;Muller glia cells: 8.2;Peritubular cells: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 6 "dendritic cells: 3.1;T-cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 27.6;ASC TERT1: 20.6;BJ hTERT+: 16.8;HSkMC: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" 9.0 4.8 3.8 1.9 6.4 0.0 7.2 32.7 11.2 29.2 7.8 1.8 4.4 1.8 22.6 9.8 5.3 7.6 5.7 7.6 3.7 4.2 3.7 8.4 4.7 2.3 2.5 5.1 8.0 1.3 2.7 7.9 7.1 11.8 8.3 4.0 8.3 3.3 9.5 7.7 6.2 3.7 17.1 3.9 2.6 4.5 5.5 4.0 0.9 3.2 2.4 2.0 6.2 8.9 0.4 3.1 0.0 0.0 0.1 2.1 0.1 0.0 1.6 1.9 0.0 27.6 20.6 1.2 7.7 16.8 6.2 6.7 4.0 2.7 1.1 2.0 15.0 11.6 0.7 2.3 0.2 5.6 1.3 0.7 1.0 1.8 2.0 15.0 0.1 0.0 20.4 1.1 6.9 0.5 6.1 10.1 1.7 0.5 0.1 11.6 0.5 0.3 0.4 2.6 0.8 2.8 1.3 0.1 0.5 1.0 0.8 0.5 0.6 0.2 0.0 0.3 3.1 0.1 0.0 6.5 6.6 5.1 2.1 0.7 0.2 0.3 3.0 8.4 0.3 3.7 0.0 0.0 0.0 1.1 0.0 0.0 0.4 1.2 0.6 0.0 0.0 0.5 0.4 0.0 0.1 0.0 3.1 2.1 0.1 3.8 6.4 32.7 11.2 3.7 4.2 2.5 5.1 11.8 4.0 3.0 4.3 0.0 0.6 1.0 4.0 0.6 0.0 1.4 0.0 0.0 2.0 0.3 0.0 0.4 0.1 2.3 0.1 0.0 0.7 0.1 5.7 1.7 1.1 5.7 0.3 3.2 0.0 2.5 0.3 0.0 8.6 0.0 0.0 0.0 0.9 8.2 0.5 3.1 7.4 0.6 2.1 0.0 1.9 2.8 2.0 1.4 0.2 0.0 1.0 0.3 NRBP1 "BCON3, MADM, MUDPNP, NRBP" ENSG00000115216 "Nuclear receptor binding protein 1" Q9UHY1 2 27427790-27442259 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029527, CAB033078" Supported Supported Cytosol NA NA 38000 Cytosol "CAB033078: AB_2154375, HPA029527: AB_10601379" "unprognostic (4.95e-3)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.38e-1)" "unprognostic (3.62e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (7.36e-2)" "unprognostic (1.44e-1)" "unprognostic (6.11e-2)" "unprognostic (3.13e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.84e-5)" "unprognostic (1.26e-1)" "unprognostic (2.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.48e-3)" 30.8 27.6 20.9 30.8 25.9 49.8 29.1 31.6 38.4 36.3 35.2 21.3 27.5 27.3 40.6 34.2 52.2 28.7 29.9 27.7 18.0 26.0 24.6 38.8 27.1 25.6 21.5 26.2 36.6 28.2 23.0 27.0 58.7 33.9 30.3 25.4 30.6 31.6 34.7 62.2 36.6 31.5 40.7 18.3 29.1 28.9 46.9 20.6 24.4 25.4 39.4 37.6 34.2 37.7 20.6 29.1 57.9 37.2 27.5 33.7 32.9 30.2 30.4 25.2 33.4 39.1 39.0 30.6 28.9 36.4 41.3 32.2 30.7 12.4 8.8 21.7 45.8 41.1 20.9 25.0 26.0 26.7 17.2 15.6 17.4 12.4 40.3 32.8 9.7 23.5 31.8 32.8 42.2 28.3 27.0 45.4 9.8 9.8 14.0 36.2 45.6 12.8 23.5 31.7 26.9 19.2 9.9 53.8 9.8 29.3 21.1 6.8 19.2 34.2 24.7 18.0 29.4 13.6 10.9 35.8 36.5 36.3 21.8 23.3 29.4 29.3 10.5 28.6 17.0 18.2 53.6 28.5 57.9 33.2 37.2 29.2 20.6 28.6 29.9 29.1 18.1 26.3 27.0 38.2 27.5 33.3 18.6 33.7 32.9 20.9 25.9 31.6 38.4 18.0 26.0 21.5 26.2 33.9 20.6 6.0 18.4 41.7 48.8 50.8 34.3 23.0 17.8 34.8 28.4 33.2 33.4 135.2 26.6 78.8 200.9 40.3 55.7 0.0 84.0 190.6 54.2 36.0 19.7 33.7 70.8 27.0 26.9 44.8 33.9 22.9 42.6 38.2 28.7 87.4 34.7 43.5 81.5 38.6 57.0 40.7 51.1 32.3 51.5 50.5 89.7 45.8 169.9 34.6 27.6 51.7 NRBP2 DKFZp434P086 ENSG00000185189 "Nuclear receptor binding protein 2" Q9NSY0 8 143833594-143840974 "Enzymes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.1" "Cell type enhanced" "Detected in many" 5 "Alveolar cells type 1: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "MAIT T-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020944, HPA029051, HPA029052" Approved Approved Cytosol NA NA Cytosol "CAB020944: , HPA029051: AB_2672886, HPA029052: AB_10602714" "unprognostic (1.84e-1)" "unprognostic (4.66e-2)" "unprognostic (2.54e-2)" "unprognostic (1.53e-3)" "unprognostic (1.01e-1)" "unprognostic (2.00e-2)" "unprognostic (4.03e-1)" "unprognostic (2.86e-1)" "unprognostic (3.97e-1)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (2.01e-5)" "unprognostic (3.86e-2)" "unprognostic (3.98e-1)" "unprognostic (4.56e-2)" "unprognostic (2.04e-1)" 18.5 10.7 21.6 6.8 21.1 1.9 10.0 17.5 32.6 7.6 13.3 47.5 8.7 8.8 11.2 10.0 9.9 14.6 11.3 15.2 23.5 14.9 14.0 18.9 14.9 4.9 30.9 23.6 10.7 10.4 8.4 8.8 6.1 30.2 17.8 6.9 10.1 22.1 15.5 7.6 23.0 9.3 12.3 54.1 7.5 10.1 6.1 27.5 1.0 9.0 3.6 3.8 8.2 7.8 0.5 0.0 0.0 0.4 0.0 1.5 0.3 5.9 7.4 6.7 8.3 10.5 16.2 1.5 12.1 5.3 4.4 6.4 1.7 5.5 0.6 3.2 14.4 3.3 9.5 3.9 4.2 1.7 7.1 2.9 1.1 19.6 3.0 10.8 0.0 2.8 20.7 10.0 2.3 2.2 14.9 6.1 2.1 3.7 7.8 9.3 2.5 0.5 0.3 2.5 6.0 4.1 2.0 6.2 2.7 6.0 2.0 2.4 4.9 15.5 7.9 6.0 4.5 11.3 0.4 14.0 2.6 8.0 12.5 3.9 4.3 0.2 0.1 13.9 2.4 3.5 0.0 0.4 0.0 0.2 0.2 1.5 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 21.6 21.1 17.5 21.4 23.5 14.9 30.9 23.6 30.2 27.5 41.7 10.7 0.8 6.0 8.1 14.2 8.1 28.1 5.3 13.6 10.4 13.7 0.7 0.0 4.0 0.3 7.1 5.1 0.0 3.6 0.9 5.8 9.0 0.0 32.1 2.4 15.9 8.6 7.4 4.1 0.0 26.7 3.2 10.1 4.6 8.4 23.2 4.7 3.5 20.1 2.8 10.6 12.9 10.3 1.1 2.3 8.0 0.7 2.9 4.5 3.7 NRK DKFZp686A17109 ENSG00000123572 "Nik related kinase" Q7Z2Y5 X 105822543-105958610 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 42.2;placenta: 64.8" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 56.0;Leydig cells: 105.0;Syncytiotrophoblasts: 56.8" "Cancer enriched" "Detected in some" 8 "testis cancer: 6.1" "Region enriched" "Detected in single" 10 "cerebellum: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 30.7;HSkMC: 5.9;RH-30: 7.0;RPTEC TERT1: 18.9;SuSa: 23.1" "Region enriched" "Detected in single" 28 "cerebellum: 16.0" "Low region specificity" "Detected in many" HPA017238 Uncertain Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA017238: AB_1854645" "unprognostic (2.64e-4)" "unprognostic (9.82e-2)" "unprognostic (5.98e-3)" "unprognostic (5.52e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (1.35e-2)" "unprognostic (6.08e-2)" "unprognostic (3.24e-2)" "unprognostic (5.28e-3)" "unprognostic (1.47e-3)" "unprognostic (1.14e-1)" "unprognostic (4.28e-2)" "unprognostic (6.80e-3)" 2.6 12.7 0.4 2.7 0.4 0.0 0.8 4.3 0.3 3.5 1.5 0.1 4.6 0.0 4.3 15.6 1.6 1.3 7.5 2.9 0.4 0.4 9.9 0.4 0.5 0.0 0.3 0.0 42.2 0.5 0.0 2.9 64.8 0.2 22.0 0.1 0.0 2.1 1.6 0.4 0.4 0.5 2.8 0.4 0.3 0.9 10.6 0.0 0.0 0.5 3.1 0.3 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 5.9 0.0 0.0 0.0 1.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 7.0 0.0 18.9 0.3 0.0 0.1 0.0 1.0 0.0 23.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 4.3 0.3 0.4 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 56.0 16.6 0.2 0.9 0.3 0.0 0.0 0.0 7.2 0.5 0.3 0.0 0.0 6.1 0.0 0.0 0.0 0.0 1.1 105.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.1 0.0 0.0 0.0 0.6 1.4 0.0 56.8 0.0 0.0 0.1 NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adrenal gland: 15.8;blood: 32.3;brain: 28.3" "Group enriched" "Detected in some" 8 "granulocytes: 56.4;Horizontal cells: 54.0" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Region enriched" "Detected in many" 5 "pons and medulla: 28.3" "Cell type enriched" "Detected in single" 127 "basophil: 32.3" "Lineage enriched" "Detected in single" 323 "granulocytes: 32.3" "Cell line enriched" "Detected in some" 4 "HMC-1: 42.1" "Region enhanced" "Detected in some" "basal ganglia: 8.2" "Low region specificity" "Detected in all" "CAB004606, HPA035799, HPA076570" Approved Approved Vesicles,Cytosol NA NA 140000 "Vesicles, Cytosol" "CAB004606: AB_628397, HPA035799: AB_2674788, HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" 1.0 15.8 0.5 0.8 6.0 0.9 0.4 0.0 0.7 0.9 1.1 0.1 0.0 0.8 1.6 2.0 0.7 0.6 2.1 1.5 0.0 1.2 2.9 0.2 1.9 0.3 2.1 0.6 0.3 0.3 0.3 1.1 0.5 28.3 2.2 0.2 3.1 1.2 0.5 0.7 0.2 0.4 1.1 1.2 0.2 1.0 2.4 1.5 0.4 0.3 0.0 0.4 0.7 0.8 0.0 0.0 32.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 6.8 0.0 0.0 0.0 0.0 42.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.6 1.2 0.0 0.1 0.0 0.0 0.8 9.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 32.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.0 0.0 0.6 0.0 1.2 2.1 0.6 28.3 1.5 0.0 2.2 0.0 0.0 0.0 6.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 56.4 0.0 0.1 54.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.2 2.5 0.1 0.0 0.0 0.0 0.0 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027070 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, Epilepsy, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;thyroid gland: 63.4" "Cell type enhanced" "Detected in many" 12 "Horizontal cells: 228.8;Leydig cells: 96.4;Muller glia cells: 248.1;Sertoli cells: 122.9;Smooth muscle cells: 96.9" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "AF22: 10.4;HaCaT: 3.7;RPTEC TERT1: 11.7;SH-SY5Y: 13.4;SuSa: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Approved Cytosol NA NA 13000000 Cytosol "CAB010346: AB_2155274, HPA007637: AB_1080385, HPA074873: " "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 19.8 2.7 66.1 2.0 56.7 1.2 33.2 15.1 133.8 6.4 4.4 27.4 0.0 1.4 3.0 3.3 5.6 3.7 18.7 5.8 61.0 30.7 12.5 2.1 6.3 2.7 32.4 41.4 6.6 18.9 1.6 3.0 2.1 34.1 3.8 3.1 2.0 8.6 11.9 2.0 7.2 1.6 3.0 22.1 6.5 1.4 2.4 34.1 0.0 63.4 2.6 3.4 3.5 3.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 11.7 0.8 0.9 13.4 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 66.1 56.7 15.1 45.6 61.0 30.7 32.4 41.4 34.1 34.1 0.0 0.3 0.0 1.0 50.4 24.4 8.7 0.0 2.7 0.0 8.7 5.9 0.0 23.2 26.5 1.5 4.5 0.0 0.0 0.6 0.1 10.6 0.9 0.0 0.0 0.2 228.8 0.0 5.5 0.0 1.7 96.4 1.2 16.9 1.0 0.0 248.1 0.5 7.2 45.3 7.9 9.1 122.9 96.9 0.7 1.1 21.5 0.0 0.0 5.4 0.8 NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.8" "Cell type enhanced" "Detected in many" 13 "Bipolar cells: 58.9;Early spermatids: 85.5;Late spermatids: 103.3;Sertoli cells: 51.8;Smooth muscle cells: 37.7" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "U-138 MG: 48.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli,Nucleoli rim" NA NA 11000000 "Nucleoli, Nucleoli rim" "Nuclear membrane" "CAB009233: AB_632555, HPA027484: AB_2672297, HPA048065: AB_2680245" "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" 20.8 7.4 22.0 2.5 28.1 1.5 6.2 30.4 41.8 7.0 4.0 8.4 1.3 2.0 12.4 6.7 3.4 9.5 3.9 5.5 22.0 11.1 5.1 2.0 5.7 3.1 11.2 18.7 5.1 2.9 1.6 7.9 2.8 14.7 6.8 4.7 8.0 11.5 8.7 1.9 2.9 2.5 7.7 13.7 4.1 3.0 13.8 13.7 0.0 2.5 0.7 4.3 7.1 4.8 0.7 0.4 1.3 0.5 0.5 0.8 0.0 0.0 6.1 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 48.6 0.9 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.1 1.2 0.5 0.4 0.3 0.1 0.2 0.4 0.3 0.3 0.1 0.7 0.4 0.4 1.3 0.5 0.1 0.4 0.8 0.0 22.0 28.1 30.4 28.9 22.0 11.1 11.2 18.7 14.7 13.7 0.0 0.0 0.0 5.9 0.5 58.9 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 85.5 0.7 0.0 0.0 0.0 0.0 1.7 0.6 0.0 0.0 0.9 1.6 0.0 1.8 0.0 103.3 3.1 0.2 0.0 0.0 0.0 8.9 0.0 0.0 25.8 0.0 2.7 51.8 37.7 8.8 1.9 0.1 0.1 0.0 0.0 0.1 NUAK1 "ARK5, KIAA0537, NuaK1" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063340-106140033 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;parathyroid gland: 18.6" "Cell type enhanced" "Detected in many" 12 "Cardiomyocytes: 46.0;Endothelial cells: 46.6;Ito cells: 119.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "AF22: 23.1;EFO-21: 23.1;RH-30: 33.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057143 Approved "Nucleoplasm,Nucleoli fibrillar center,Microtubules" Yes No "Nucleoli fibrillar center" "Nucleoplasm, Microtubules" "HPA057143: AB_2683349" "unprognostic (4.20e-2)" "unprognostic (8.42e-2)" "unprognostic (3.71e-2)" "prognostic unfavorable (9.83e-4)" "unprognostic (4.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (4.80e-2)" "unprognostic (9.91e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-1)" "unprognostic (1.31e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.31e-1)" "unprognostic (8.70e-2)" "unprognostic (4.47e-2)" 8.2 1.8 4.2 2.0 13.0 0.0 5.5 9.9 20.1 4.6 1.7 24.3 1.1 1.0 5.8 1.6 1.9 3.6 2.7 11.3 5.1 3.3 2.5 2.4 4.9 1.5 8.7 8.4 3.2 1.2 18.6 1.9 2.5 7.6 3.6 2.2 2.3 1.8 3.7 9.4 11.6 1.5 6.3 5.5 1.1 1.5 1.3 9.3 1.1 1.8 1.1 1.4 3.4 3.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 5.0 3.4 23.1 0.2 9.3 1.0 10.7 5.7 3.9 4.4 3.3 1.7 0.8 0.0 23.1 10.4 1.9 4.8 4.8 4.6 2.1 0.0 1.3 0.0 3.7 1.8 1.9 0.0 0.0 4.8 3.1 2.5 0.8 7.6 8.4 0.0 0.0 16.8 3.1 0.5 0.1 0.2 4.5 0.0 1.4 0.0 33.2 4.0 2.5 5.9 2.7 0.1 2.6 0.8 0.2 15.9 1.2 0.1 6.2 3.8 12.9 1.4 6.8 0.0 0.0 0.3 1.1 0.0 3.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.2 13.0 9.9 17.5 5.1 3.3 8.7 8.4 7.6 9.3 0.0 3.7 0.0 32.0 11.9 30.8 46.0 2.5 0.0 5.7 7.0 0.0 0.4 3.3 5.0 0.3 46.6 0.0 23.3 8.3 4.1 9.2 4.4 0.0 10.5 6.1 38.1 0.0 119.1 9.7 1.7 3.7 1.3 10.1 1.0 2.0 1.7 11.7 0.0 2.8 1.4 2.6 0.0 14.4 0.7 5.5 13.9 0.2 0.9 0.9 3.7 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302059-205321791 "Enzymes, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 42.4" "Cell type enhanced" "Detected in many" 6 "Collecting duct cells: 31.4;Ductal cells: 40.9;monocytes: 48.7;Mucus-secreting cells: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in all" "neutrophil: 42.4" "Group enriched" "Detected in all" 4 "B-cells: 15.3;granulocytes: 42.4;T-cells: 10.7" "Cell line enhanced" "Detected in many" "BEWO: 22.8;RPMI-8226: 17.6;RPTEC TERT1: 20.9;SuSa: 24.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favorable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 1.4 2.8 0.8 12.5 2.4 8.3 0.9 9.2 1.5 18.9 10.4 3.9 2.4 13.6 2.7 3.8 31.3 3.4 1.3 1.1 1.7 1.0 14.5 3.6 16.2 20.3 5.5 1.5 3.3 13.2 0.1 2.3 7.2 2.0 1.5 7.5 9.8 9.7 2.0 0.7 12.9 15.4 0.9 2.7 10.4 2.0 5.6 2.4 5.5 14.5 20.1 31.7 2.8 24.6 15.3 3.6 42.4 5.6 5.7 10.7 5.4 2.1 11.6 7.1 0.3 0.1 0.3 22.8 2.8 2.9 7.6 3.1 12.2 0.4 3.4 1.7 0.7 12.5 4.2 1.6 4.2 3.3 0.0 0.2 0.0 0.7 2.1 4.9 0.0 0.0 1.3 3.1 4.4 2.6 1.7 0.3 0.0 0.4 0.9 1.4 0.5 0.0 0.0 4.5 1.5 0.3 0.0 0.5 17.6 20.9 0.0 1.1 0.1 0.8 3.3 0.3 24.7 3.3 0.0 0.8 2.7 1.3 0.3 4.3 6.2 0.9 2.1 0.4 0.0 1.0 3.4 5.6 13.2 3.9 4.2 2.8 14.2 4.8 4.6 3.6 15.3 10.7 8.1 42.4 5.7 4.1 1.4 2.8 5.4 0.8 2.4 9.2 1.5 1.7 1.0 5.5 1.5 2.0 2.4 6.0 5.0 9.1 0.8 1.0 0.8 1.4 20.4 2.7 0.0 31.4 0.0 6.5 5.0 40.9 1.7 2.2 20.3 0.0 1.5 27.7 4.0 1.8 0.0 2.9 4.6 0.0 10.4 1.3 11.7 1.2 0.0 6.5 6.8 48.7 40.0 1.7 7.2 2.9 0.0 15.0 0.5 6.5 2.5 0.5 0.9 4.6 3.4 4.5 18.7 0.2 OBSCN "ARHGEF30, KIAA1556, KIAA1639, UNC89" ENSG00000154358 "Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" Q5VST9 1 228208130-228378874 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Calmodulin-binding, Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 180.2;tongue: 48.4" "Cell type enriched" "Detected in many" 14 "Cardiomyocytes: 136.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 16.0" "Low region specificity" "Detected in single" "HPA021186, HPA065801" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA021186: AB_1854761, HPA065801: " "unprognostic (8.47e-3)" "unprognostic (1.56e-1)" "unprognostic (9.99e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (5.30e-3)" "unprognostic (6.36e-2)" "unprognostic (4.54e-3)" "unprognostic (1.82e-1)" "unprognostic (8.81e-2)" "unprognostic (1.93e-2)" "unprognostic (3.38e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-2)" 2.5 0.9 0.5 0.9 4.4 0.6 0.7 3.1 0.6 0.6 0.8 0.5 0.5 0.6 0.8 4.4 2.4 1.0 0.6 21.2 0.5 0.7 1.6 0.5 1.0 1.0 0.5 0.5 1.7 1.4 0.4 2.4 0.5 0.9 1.7 0.3 5.2 2.6 1.1 180.2 1.1 0.8 0.5 0.6 1.4 0.5 0.7 0.6 0.5 2.2 48.4 3.5 0.6 0.7 1.0 1.1 0.1 0.4 0.6 3.2 0.7 2.9 2.8 8.0 4.5 0.2 0.1 5.6 1.5 0.5 1.0 0.9 2.0 2.1 5.7 8.1 0.5 0.6 1.0 0.4 1.1 0.2 2.2 5.1 1.9 16.0 0.0 2.0 1.3 6.1 3.0 1.0 0.4 0.2 5.4 0.4 9.4 5.3 1.3 0.3 5.0 2.1 1.6 8.8 0.8 1.8 8.1 0.1 1.3 4.6 1.5 3.0 9.0 0.2 2.9 1.1 2.4 8.0 3.7 0.7 0.0 9.3 0.2 0.1 4.7 0.9 1.4 0.0 0.8 2.1 0.1 0.4 0.0 0.9 0.1 0.9 0.5 0.9 0.7 0.9 1.0 3.2 0.5 0.1 0.6 0.1 1.1 0.8 0.7 0.5 4.4 3.1 0.6 0.5 0.7 0.5 0.5 0.9 0.6 0.0 5.6 0.0 5.9 1.9 3.2 136.5 2.5 1.4 4.5 5.2 9.8 0.1 10.0 2.9 3.8 1.6 0.4 0.0 0.4 0.4 1.5 1.9 6.9 0.5 0.1 0.0 0.0 1.3 0.0 4.0 2.8 0.3 1.7 0.0 1.7 9.7 1.0 0.0 4.2 4.2 2.8 0.0 1.2 0.1 2.5 1.5 1.0 1.8 1.1 3.4 OXSR1 "KIAA1101, OSR1" ENSG00000172939 "Oxidative stress responsive 1" O95747 3 38165089-38255488 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Urothelial cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008237, CAB017181" Supported Enhanced Cytosol NA NA 21000000 Cytosol "CAB017181: , HPA008237: AB_1079540" "unprognostic (2.16e-1)" "unprognostic (2.36e-2)" "unprognostic (1.79e-2)" "unprognostic (4.55e-3)" "unprognostic (9.89e-2)" "unprognostic (1.97e-2)" "unprognostic (3.53e-3)" "unprognostic (4.05e-2)" "unprognostic (4.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.95e-3)" "unprognostic (1.88e-2)" "unprognostic (1.87e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-2)" "unprognostic (1.71e-1)" "unprognostic (6.99e-3)" 17.6 16.8 9.4 18.3 13.4 24.2 15.9 17.4 14.9 16.8 15.4 9.2 35.7 12.4 14.9 14.7 31.6 11.6 18.9 15.5 11.9 9.0 18.3 17.6 14.6 13.9 13.6 9.3 16.7 12.3 23.7 15.3 21.4 12.3 16.5 16.8 13.0 15.1 23.9 32.6 17.4 21.4 17.0 12.9 15.8 14.0 11.2 13.2 26.2 14.2 24.1 19.6 23.5 19.2 2.3 4.4 10.1 4.8 5.0 4.7 1.6 17.7 8.1 16.3 11.3 11.4 13.2 18.5 15.7 21.6 22.8 24.8 10.5 11.6 19.7 8.0 18.8 9.8 11.1 21.8 16.2 30.1 20.8 8.9 21.5 17.3 11.4 13.6 13.3 13.2 10.4 19.1 21.0 34.1 21.5 14.2 25.5 16.3 11.4 39.0 5.0 25.6 9.6 17.1 11.5 9.7 8.9 13.6 15.2 14.0 13.5 8.5 13.1 17.2 43.6 10.7 18.7 14.3 8.7 12.9 14.3 14.2 21.7 23.2 8.7 10.3 14.5 19.7 16.6 28.5 10.1 2.8 6.1 3.3 4.8 3.5 1.9 4.0 3.1 4.4 2.3 3.0 3.7 5.5 5.0 4.1 2.5 4.7 1.6 9.4 13.4 17.4 14.9 11.9 9.0 13.6 9.3 12.3 13.2 11.9 26.3 13.3 24.0 39.2 11.8 26.6 2.5 12.0 27.3 26.2 19.6 9.4 16.6 25.2 3.1 17.1 28.7 0.0 12.5 15.6 14.9 44.7 15.1 17.8 13.4 20.6 23.2 12.3 32.9 1.4 8.9 28.2 6.8 33.3 18.0 7.6 33.8 24.6 12.0 19.4 5.5 12.9 26.7 12.7 15.0 45.4 27.6 17.5 15.3 110.3 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77321707-77474635 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 70.0;brain: 71.4" "Cell type enhanced" "Detected in many" 4 "granulocytes: 126.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 29.3;eosinophil: 45.0;intermediate monocyte: 28.7;myeloid DC: 42.3;neutrophil: 70.0;non-classical monocyte: 30.4" "Group enriched" "Detected in all" 11 "dendritic cells: 42.3;granulocytes: 70.0;monocytes: 30.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 200000 "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 5.4 6.0 30.5 13.8 39.5 22.9 7.8 49.1 71.4 9.8 18.2 8.4 2.3 18.2 9.1 13.3 9.9 9.8 13.2 5.3 19.0 16.9 11.3 6.0 6.9 7.5 12.8 40.6 10.4 9.2 11.8 10.8 11.9 39.2 12.2 20.2 5.4 10.4 8.8 34.0 6.7 18.9 11.6 7.8 11.7 17.1 11.1 6.6 7.6 17.7 3.9 9.4 10.5 10.4 2.7 42.3 70.0 30.4 4.3 2.4 12.2 11.4 7.7 16.8 7.6 6.8 11.5 13.4 13.1 9.4 12.4 14.7 11.0 15.3 10.2 4.8 11.3 16.2 5.9 11.7 13.8 19.7 11.8 9.4 10.8 5.2 0.7 4.5 18.2 16.0 8.5 8.4 14.6 21.7 11.0 2.9 12.0 7.1 18.0 22.6 0.8 11.6 8.4 24.7 47.4 6.6 17.8 21.7 0.4 3.1 9.5 7.2 7.1 7.0 3.0 5.5 17.3 13.4 8.3 0.2 8.3 14.4 44.3 10.9 49.6 25.5 6.8 6.9 12.2 8.9 0.3 29.3 45.0 1.9 28.7 1.5 2.7 1.4 1.8 42.3 1.9 1.3 2.4 70.0 4.3 30.4 3.6 1.1 12.2 30.5 39.5 49.1 71.4 19.0 16.9 12.8 40.6 39.2 6.6 3.0 21.5 16.1 27.9 10.5 48.2 3.1 33.1 41.5 33.0 24.4 7.9 23.0 38.1 26.3 31.5 3.0 46.3 0.0 49.4 46.4 13.1 25.6 126.2 10.9 45.2 1.6 36.2 3.1 43.9 20.0 13.3 71.3 28.7 94.6 47.0 14.0 41.8 55.2 12.4 28.6 6.7 12.9 18.2 25.6 42.1 9.2 79.4 12.2 47.1 27.2 PAK2 "PAK65, PAKgamma" ENSG00000180370 "P21 (RAC1) activated kinase 2" Q13177 3 196739857-196832647 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Growth regulation, Host-virus interaction" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007794 Approved Approved Nucleoplasm,Vesicles NA NA 590000 "Nucleoplasm, Vesicles" "CAB007794: AB_562363" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" "unprognostic (2.52e-1)" "unprognostic (2.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.80e-1)" "unprognostic (5.18e-3)" "unprognostic (1.85e-2)" "unprognostic (7.97e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.36e-4)" "prognostic unfavorable (9.58e-4)" "unprognostic (1.30e-3)" "unprognostic (4.57e-2)" "unprognostic (1.25e-2)" "unprognostic (1.70e-2)" "unprognostic (3.39e-1)" 28.7 18.9 22.4 27.6 23.5 21.4 56.5 17.4 20.7 19.5 23.0 27.8 17.4 19.0 22.6 19.2 23.4 17.9 20.7 29.0 22.6 22.0 19.5 34.3 35.7 50.2 26.8 13.5 19.9 16.6 30.5 13.0 27.6 22.8 17.7 23.0 12.9 19.6 21.2 34.2 16.3 25.2 23.0 32.1 34.6 18.4 15.9 24.8 44.9 16.9 19.1 31.9 24.1 32.7 6.6 13.7 25.9 12.6 6.6 10.8 7.0 36.0 12.9 18.1 13.3 12.9 17.1 27.0 18.3 15.1 19.9 18.1 30.6 18.5 23.1 52.3 18.4 20.3 18.5 19.2 17.4 30.8 10.4 9.3 34.2 14.9 24.0 26.2 33.2 32.9 13.6 14.3 17.8 37.9 21.1 19.6 25.7 16.4 28.8 19.3 38.0 31.6 17.2 10.8 19.4 19.5 28.9 10.3 20.9 17.4 25.3 10.6 12.1 24.5 17.3 13.8 14.6 60.5 24.1 20.2 16.5 9.2 17.3 26.9 19.6 34.6 56.9 13.7 33.3 15.7 16.5 10.3 24.5 6.3 12.6 8.5 6.4 7.3 7.1 13.7 6.6 5.4 6.3 25.9 6.6 10.8 5.1 10.8 7.0 22.4 23.5 17.4 20.7 22.6 22.0 26.8 13.5 22.8 24.8 74.5 44.7 76.2 49.3 86.5 39.1 56.5 63.7 88.3 47.8 78.5 49.1 41.1 28.2 62.3 49.4 78.8 52.5 0.0 51.3 82.8 47.0 116.6 143.4 125.4 90.3 52.4 43.1 63.3 144.6 51.0 56.4 118.7 32.1 120.0 42.8 58.0 77.2 48.4 42.8 60.3 40.6 38.8 52.3 24.2 41.4 75.4 29.2 71.3 38.3 112.3 PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 26.2;pancreas: 46.5;pituitary gland: 37.2" "Cell type enhanced" "Detected in many" 13 "Bipolar cells: 81.5;Leydig cells: 31.7;Peritubular cells: 76.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6 "MAIT T-cell: 4.3" "Lineage enriched" "Detected in single" 7 "T-cells: 4.3" "Cell line enhanced" "Detected in some" "EFO-21: 9.8;HAP1: 8.8;HDLM-2: 11.0;NTERA-2: 8.6;SCLC-21H: 11.2;SH-SY5Y: 7.0;U-2197: 6.8;U-251 MG: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Vesicles NA NA Vesicles "HPA044791: , HPA060219: AB_2684223" "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-4)" "unprognostic (2.46e-1)" "unprognostic (5.63e-3)" "unprognostic (7.29e-2)" "unprognostic (3.23e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-1)" "unprognostic (6.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.89e-4)" "unprognostic (5.71e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" 2.0 6.8 17.6 2.5 17.5 1.0 6.4 1.8 24.6 3.7 1.6 0.9 9.1 1.0 6.8 7.6 1.7 3.7 2.6 1.2 26.2 20.8 1.6 1.1 1.8 2.5 7.9 21.9 7.9 46.5 0.9 37.2 1.6 12.9 4.8 1.7 1.4 3.0 7.1 2.4 2.0 1.4 6.1 5.8 2.9 3.0 3.6 1.9 0.0 7.7 0.0 1.7 2.0 1.5 0.1 0.1 0.6 0.1 0.2 4.3 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 9.8 1.0 1.4 0.0 8.8 0.5 1.2 11.0 0.3 0.0 1.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 2.0 5.2 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.1 8.6 0.0 1.9 0.1 4.0 0.0 0.8 0.0 11.2 7.0 0.0 0.4 0.0 6.2 0.0 0.0 0.0 0.6 4.3 6.8 11.7 0.0 0.1 0.1 1.2 0.0 0.1 0.6 0.1 0.1 0.1 0.0 4.3 0.0 0.7 0.4 0.0 0.1 0.1 0.1 0.5 0.2 0.1 0.1 0.3 0.0 17.6 17.5 1.8 18.5 26.2 20.8 7.9 21.9 12.9 1.9 3.0 1.4 0.0 14.1 0.2 81.5 0.8 12.7 0.0 1.2 0.0 0.0 0.3 0.0 3.0 3.4 2.4 0.0 0.0 11.6 0.3 5.8 1.3 1.1 0.0 0.2 6.4 3.5 0.6 0.3 4.7 31.7 2.0 0.0 1.0 0.0 19.0 7.3 0.0 76.4 0.5 5.5 0.0 0.4 1.1 0.6 1.0 5.6 2.2 0.0 0.9 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 45.4;MCF7: 50.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavorable (9.85e-4)" "prognostic favorable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 6.8 11.1 11.0 12.7 12.3 4.8 11.9 13.7 12.4 17.3 19.6 13.7 19.9 26.0 12.2 17.3 20.1 15.3 16.5 8.1 10.9 8.1 19.4 17.0 18.7 5.4 13.7 7.7 13.8 29.6 11.2 17.0 23.0 10.3 29.6 8.1 19.7 40.9 18.5 10.3 18.6 25.1 9.0 8.3 7.9 18.6 22.3 12.5 8.8 15.2 10.1 14.7 11.5 15.0 2.8 3.4 4.2 2.5 3.6 4.5 1.9 17.9 45.4 6.8 10.3 2.1 2.3 20.5 8.6 3.5 5.8 5.9 29.7 15.3 4.1 13.1 5.4 7.6 6.6 3.7 6.8 2.2 10.9 10.4 4.8 8.3 14.4 3.4 4.9 7.1 2.7 3.0 5.4 3.9 3.8 7.5 6.3 9.7 3.2 3.4 50.0 5.2 5.4 12.3 15.9 10.9 5.3 5.3 3.1 5.6 19.8 21.7 15.0 8.7 39.0 9.7 3.7 17.3 8.2 12.5 9.9 17.0 11.3 15.3 3.7 3.5 3.4 12.1 2.9 11.8 1.0 2.5 4.2 2.6 1.4 3.6 2.2 2.9 4.5 3.4 2.8 2.2 2.2 2.1 3.6 2.1 2.9 3.0 1.9 11.0 12.3 13.7 12.4 10.9 8.1 13.7 7.7 10.3 12.5 0.0 1.0 0.5 15.0 12.8 14.8 1.2 20.4 6.7 0.0 17.4 23.6 35.6 26.6 18.7 2.7 15.8 35.5 0.0 17.2 46.7 10.8 17.8 5.7 10.5 8.3 20.6 43.0 12.3 5.6 4.9 10.9 2.5 6.8 14.4 30.6 14.1 16.5 40.3 9.9 10.6 13.1 0.0 7.2 5.7 17.7 16.4 54.7 8.7 29.9 20.6 PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537389-9839041 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 30.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "SCLC-21H: 10.2;SH-SY5Y: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020444 Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA020444: AB_1854947" "unprognostic (5.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.05e-1)" "unprognostic (8.63e-2)" "unprognostic (3.21e-1)" "unprognostic (3.04e-1)" "unprognostic (2.25e-4)" "unprognostic (3.76e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-1)" "unprognostic (3.35e-2)" "unprognostic (6.04e-2)" "unprognostic (4.58e-1)" 0.5 5.2 5.7 0.6 11.7 0.5 1.6 30.3 19.6 0.8 0.6 0.8 0.0 0.7 1.0 2.2 1.0 0.7 3.4 0.6 4.0 3.3 1.0 2.3 0.7 0.6 1.6 8.8 0.6 3.5 0.5 2.0 0.6 5.3 1.6 0.6 0.6 1.2 1.6 0.6 1.6 0.6 0.6 1.2 0.6 1.2 1.0 1.7 0.0 0.6 0.0 0.6 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 3.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 5.7 11.7 30.3 13.6 4.0 3.3 1.6 8.8 5.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40238759-40277487 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 22.2" "Cell type enhanced" "Detected in many" 11 "Cytotrophoblasts: 38.8;Suprabasal keratinocytes: 16.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 14.8;HaCaT: 23.0;hTCEpi: 14.1;SK-BR-3: 7.8" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.3 5.3 14.7 0.8 18.4 0.8 2.3 11.3 20.1 3.0 1.3 1.6 2.5 1.4 1.0 1.1 15.8 4.3 1.4 7.9 11.6 5.2 3.4 0.4 2.6 1.0 3.0 10.9 0.6 7.4 12.9 6.4 8.1 2.1 3.6 1.2 0.3 3.4 7.5 3.5 22.2 1.4 0.8 1.2 1.0 3.6 12.8 2.2 0.0 7.4 8.5 5.1 3.0 5.1 1.4 0.7 2.9 0.7 2.0 5.5 1.2 2.7 0.0 0.2 0.1 0.0 0.0 4.4 0.0 0.1 0.6 0.4 14.8 2.0 0.1 2.4 0.0 0.9 23.0 3.3 4.9 0.2 0.1 0.7 0.0 1.9 0.1 0.0 0.1 0.3 0.0 14.1 0.2 3.3 0.2 0.0 3.9 1.1 0.2 0.0 3.2 0.0 0.3 0.4 2.7 2.0 0.2 0.1 1.8 1.1 6.0 5.4 1.3 1.9 7.8 0.2 1.3 0.9 7.2 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.5 0.4 0.1 2.1 0.7 2.9 5.5 0.3 2.1 1.4 0.5 4.2 0.7 0.5 0.3 1.2 1.3 2.0 0.2 0.5 0.1 1.2 14.7 18.4 11.3 20.1 11.6 5.2 3.0 10.9 2.1 2.2 0.0 3.4 0.0 6.8 8.8 3.9 0.0 7.6 4.0 4.5 5.2 0.0 38.8 11.6 4.0 5.9 0.0 0.0 0.0 3.7 1.2 0.6 4.0 0.0 0.0 3.5 0.0 4.7 0.0 0.3 4.5 1.7 0.3 1.7 0.0 0.8 1.4 2.7 0.0 1.8 0.0 0.0 0.0 0.1 1.6 1.5 16.7 7.6 1.3 1.9 6.8 PAN3 ENSG00000152520 "PAN3 poly(A) specific ribonuclease subunit" Q58A45 13 28138506-28295335 "Enzymes, Predicted intracellular proteins" "mRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028817 Approved NA NA "HPA028817: AB_10602016" "unprognostic (3.25e-2)" "unprognostic (2.10e-1)" "unprognostic (3.55e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (7.39e-2)" "unprognostic (8.17e-2)" "unprognostic (1.52e-1)" "unprognostic (4.26e-3)" "unprognostic (5.78e-2)" "unprognostic (6.56e-2)" "unprognostic (2.29e-2)" "unprognostic (4.22e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (8.54e-2)" "unprognostic (2.42e-2)" 15.2 9.0 8.3 18.6 7.7 20.0 13.9 41.7 10.1 12.1 12.5 10.7 13.0 7.0 15.2 17.8 12.3 10.5 9.0 7.8 8.6 4.5 8.1 5.9 14.4 14.3 10.3 6.8 12.8 10.4 9.2 10.1 11.4 8.5 10.3 9.5 11.0 15.9 12.3 9.6 16.0 12.6 10.2 6.2 16.0 10.5 12.4 10.7 25.2 13.3 7.9 14.8 17.5 12.4 12.3 14.8 21.6 12.5 11.5 12.3 8.7 5.8 3.9 9.6 9.8 4.8 6.7 7.8 6.0 9.4 6.3 6.1 6.0 11.9 20.5 4.7 8.7 7.3 8.6 9.1 6.2 10.6 13.2 4.5 16.6 4.7 4.9 6.5 12.6 10.0 7.0 6.6 5.0 10.7 7.9 8.4 9.4 8.8 6.1 6.3 7.0 13.7 26.7 10.3 7.4 3.9 32.5 11.0 7.2 9.1 7.6 9.5 7.6 7.2 9.8 7.9 6.2 5.3 22.3 8.3 6.0 5.5 5.9 5.6 4.9 3.8 21.1 3.9 8.9 7.6 18.8 10.1 12.2 9.5 9.2 9.9 12.3 10.7 9.5 9.4 11.8 12.3 11.7 21.6 11.5 12.5 14.8 8.0 8.7 8.3 7.7 41.7 10.1 8.6 4.5 10.3 6.8 8.5 10.7 14.9 15.0 35.0 14.5 58.8 25.9 5.9 12.7 9.4 13.6 15.7 27.5 14.0 1.7 11.1 11.3 24.1 11.1 23.3 11.1 13.6 14.1 26.7 16.1 9.0 12.4 25.4 26.0 23.4 45.9 10.4 24.5 31.5 54.0 32.5 19.0 13.0 10.8 20.1 20.5 11.0 33.3 12.9 17.8 20.2 22.6 70.6 20.1 30.5 15.3 23.3 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.1;testis: 22.0" "Cell type enhanced" "Detected in many" 6 "Ito cells: 27.0;Peritubular cells: 23.0;Rod photoreceptor cells: 17.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 24.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA016450, HPA021079" Uncertain Supported Cytosol NA NA Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.5 1.1 2.4 10.3 24.1 8.9 3.1 6.3 5.2 2.2 2.1 2.2 2.1 3.8 2.9 6.7 3.1 7.2 3.3 1.1 2.9 2.7 3.7 1.3 3.0 14.5 1.3 1.6 1.9 3.3 4.4 4.9 1.1 3.6 12.1 2.8 4.7 2.7 1.8 2.0 4.9 3.9 1.4 1.6 4.4 3.4 22.0 7.2 9.0 4.8 1.9 9.9 2.7 1.9 7.1 1.1 4.8 1.0 2.7 6.0 3.0 5.0 6.8 9.2 11.6 0.8 1.4 12.3 4.8 1.5 4.5 6.3 5.5 5.1 2.6 1.0 1.1 10.0 12.6 10.4 4.2 3.3 10.6 9.9 7.2 12.6 9.7 0.5 9.8 11.3 0.7 3.3 4.6 1.3 1.9 3.2 11.2 9.3 3.6 3.1 5.7 11.6 10.3 10.2 5.9 4.1 18.5 9.3 3.2 1.7 11.4 16.3 4.9 2.9 5.6 2.1 5.1 4.7 7.1 4.2 6.1 5.6 7.8 6.4 4.8 4.9 12.4 3.8 7.4 5.6 4.8 1.0 0.7 1.7 0.6 1.5 7.1 5.9 5.3 1.1 6.6 3.7 3.9 1.3 2.7 1.0 0.7 6.0 3.0 2.4 24.1 6.3 5.2 2.9 2.7 1.3 1.6 3.6 7.2 3.0 9.3 10.6 1.0 2.4 2.3 2.8 2.5 6.7 1.2 3.5 3.9 0.8 0.0 1.2 7.7 2.4 1.8 0.0 1.8 1.5 0.9 2.5 3.5 1.0 1.6 1.6 0.0 27.0 5.3 2.2 5.5 1.9 11.8 1.0 2.9 1.6 0.6 0.0 23.0 1.0 17.7 0.0 0.3 14.7 12.7 1.3 0.2 13.1 2.7 0.7 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809620-27838095 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 19.4;testis: 67.9" "Group enriched" "Detected in many" 4 "Early spermatids: 218.2;Spermatocytes: 187.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 2.1;T-reg: 1.6" "Group enriched" "Detected in many" 10 "NK-cells: 2.1;T-cells: 1.6" "Cell line enhanced" "Detected in many" "A-431: 61.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 0.6 0.8 0.2 7.7 0.3 3.3 1.3 0.3 0.4 1.1 3.8 0.3 0.2 3.7 0.4 0.6 6.2 0.3 0.8 3.3 0.3 0.2 0.7 0.9 1.2 5.4 0.3 0.2 0.4 0.4 0.0 0.2 2.2 0.3 0.4 4.6 0.2 1.1 0.2 0.4 1.9 3.6 0.9 0.6 1.7 1.7 67.9 0.2 19.4 0.3 4.7 5.3 0.7 1.9 0.1 0.0 0.0 0.0 2.1 1.6 0.5 61.3 20.0 19.7 12.5 1.9 3.5 8.3 28.2 13.4 29.0 24.5 6.9 11.4 32.7 10.0 10.8 32.3 16.3 18.9 9.5 31.9 8.0 10.2 7.8 14.2 10.1 0.1 5.1 11.7 0.9 7.8 13.4 7.2 5.2 14.6 16.2 11.5 22.0 34.2 6.9 19.3 6.0 3.5 16.6 17.4 12.1 27.4 8.8 10.9 9.5 7.8 12.2 10.5 12.4 15.8 5.7 13.0 7.8 8.5 19.1 46.0 24.2 29.9 3.1 8.7 15.1 11.6 9.0 41.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 1.6 0.5 0.2 0.3 0.3 0.4 0.3 0.2 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.9 7.9 0.0 0.3 5.1 0.0 2.3 0.0 0.0 3.1 0.0 0.5 218.2 0.0 1.3 46.7 0.0 40.6 2.9 0.7 0.0 1.0 4.2 0.0 0.0 7.4 1.9 37.5 7.8 0.6 0.0 0.0 4.3 0.0 0.2 0.0 2.8 0.0 0.0 6.5 0.5 187.0 31.0 2.0 5.6 0.0 5.3 0.7 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229097-54298247 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 81.5" "Group enriched" "Detected in many" 9 "Fibroblasts: 171.4;Leydig cells: 416.6;Peritubular cells: 384.4" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 82.8;ASC TERT1: 38.8;BJ hTERT+: 48.0;fHDF/TERT166: 33.4;HHSteC: 28.0;HSkMC: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 150000 "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 35.0 12.4 12.6 16.1 7.6 0.9 17.2 2.4 20.1 33.2 19.1 9.2 6.4 9.6 27.6 14.6 21.9 22.5 16.2 15.3 8.9 7.4 22.8 8.4 24.1 26.9 9.2 4.0 81.5 6.8 1.6 2.1 25.1 7.2 18.6 15.2 19.2 8.5 8.3 11.9 7.0 17.4 19.7 8.8 51.6 13.6 19.0 9.3 0.5 11.3 12.8 4.3 35.9 24.6 0.9 0.4 2.5 0.4 0.3 0.8 0.3 0.0 0.0 0.2 0.1 82.8 38.8 0.1 4.3 48.0 0.0 0.1 11.5 0.0 0.1 0.1 33.4 0.1 0.1 3.3 0.0 0.0 0.4 0.1 0.1 0.1 0.2 28.0 0.0 0.0 70.4 0.0 5.5 0.0 0.9 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 6.7 0.0 0.1 0.0 0.3 0.1 0.0 0.1 15.2 0.5 16.6 0.0 0.0 0.0 0.1 0.4 0.0 0.3 2.5 0.4 0.2 0.5 0.2 0.2 0.6 0.8 0.4 0.0 0.9 0.7 0.4 2.3 0.3 0.3 0.4 0.2 0.3 12.6 7.6 2.4 7.3 8.9 7.4 9.2 4.0 7.2 9.3 0.0 0.3 0.9 0.3 15.1 0.7 4.0 0.0 0.0 0.0 0.0 0.0 1.3 1.7 2.9 1.6 3.3 0.0 0.0 5.8 1.2 171.4 0.4 0.0 0.8 2.8 0.0 0.0 38.1 0.6 3.7 416.6 1.6 21.9 8.2 0.0 18.3 12.2 0.0 384.4 0.0 0.4 0.0 13.2 1.1 3.5 13.8 1.1 0.0 0.0 0.8 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113837-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Sertoli cells: 1267.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "gdT-cell: 2.9;non-classical monocyte: 4.1" "Group enriched" "Detected in many" 8 "monocytes: 4.1;T-cells: 2.9" "Group enriched" "Detected in some" 4 "ASC diff: 173.0;ASC TERT1: 59.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 35000000 Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" 61.8 10.4 8.3 11.0 9.1 0.5 66.1 4.6 10.4 73.1 15.7 6.7 6.9 5.1 44.3 17.3 21.7 26.1 51.7 24.2 8.2 3.9 17.0 4.6 28.9 21.5 7.9 8.1 46.5 7.5 10.4 7.7 46.4 7.7 24.2 6.3 22.9 11.2 19.3 29.8 20.3 11.2 29.8 5.0 19.6 9.2 21.5 6.7 1.4 21.4 16.0 7.3 23.6 35.1 0.4 0.1 0.0 4.1 0.0 2.9 0.6 0.0 0.0 1.0 0.0 173.0 59.9 0.4 6.0 25.1 4.2 7.1 0.6 0.0 0.0 0.8 17.3 2.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.4 24.5 0.0 0.0 27.0 0.0 5.8 0.0 13.5 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 1.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.8 2.2 2.9 0.3 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 2.9 0.6 0.0 0.4 0.1 0.8 0.1 0.1 0.0 1.3 0.0 0.0 4.1 0.0 0.0 0.6 8.3 9.1 4.6 10.4 8.2 3.9 7.9 8.1 7.7 6.7 0.0 0.6 0.0 0.5 21.3 5.0 13.4 0.0 1.4 0.0 1.8 3.9 0.6 0.0 0.0 0.8 16.2 0.0 0.0 0.0 1.0 68.8 0.6 0.0 1.5 1.4 0.0 0.0 6.7 0.0 4.7 153.1 2.2 23.6 1.0 0.0 74.9 0.1 0.0 191.6 0.0 1.1 1267.6 273.4 1.1 1.5 13.4 0.7 1.0 0.4 0.9 PDIK1L CLIK1L ENSG00000175087 "PDLIM1 interacting kinase 1 like" Q8N165 1 26111165-26125543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Horizontal cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064157 Supported Nucleoplasm NA NA Nucleoplasm "HPA064157: " "unprognostic (1.09e-1)" "unprognostic (1.81e-3)" "unprognostic (2.99e-3)" "unprognostic (2.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.34e-3)" "unprognostic (3.93e-2)" "unprognostic (1.72e-3)" "unprognostic (7.29e-3)" "unprognostic (1.08e-1)" "unprognostic (2.42e-2)" "unprognostic (3.59e-1)" "unprognostic (1.34e-2)" "unprognostic (4.24e-3)" "unprognostic (2.94e-1)" "unprognostic (4.47e-1)" "unprognostic (1.78e-2)" 7.0 6.0 8.6 6.2 12.3 19.9 11.5 17.8 15.9 8.6 8.9 7.1 7.6 9.5 7.8 6.4 11.4 7.5 5.8 4.8 8.5 10.6 8.5 11.3 6.7 8.0 9.3 9.9 10.2 15.3 10.7 9.9 5.6 11.5 6.8 10.6 6.1 10.2 8.9 7.7 9.4 9.7 6.5 8.3 8.3 10.2 7.8 9.3 19.1 22.2 6.7 8.8 8.8 8.0 6.7 9.3 11.0 6.1 5.6 10.4 5.2 5.5 2.1 5.9 7.4 2.3 3.1 1.9 1.4 2.0 3.8 2.5 1.4 8.0 11.7 4.3 2.1 3.0 4.1 7.8 2.9 3.6 4.2 5.2 10.4 3.3 1.5 3.4 10.9 6.3 1.6 4.2 3.4 6.7 2.6 3.4 11.4 12.3 11.7 1.3 3.1 15.8 4.9 2.7 6.8 3.2 8.4 5.4 14.0 2.5 4.4 9.4 8.0 5.6 7.1 7.2 1.6 4.1 3.7 3.1 4.1 3.6 5.2 4.6 17.5 17.2 8.9 4.3 13.6 3.9 11.0 5.0 4.2 6.7 4.6 6.2 6.7 9.4 7.4 9.3 5.6 10.0 8.0 0.5 5.6 6.1 3.5 10.4 5.2 8.6 12.3 17.8 15.9 8.5 10.6 9.3 9.9 11.5 9.3 8.9 3.4 4.5 1.8 2.9 17.8 1.6 10.2 9.4 7.9 1.8 0.0 3.2 0.0 2.7 0.9 3.5 3.9 0.0 3.5 0.4 2.6 3.1 6.9 9.7 3.4 22.3 12.6 3.1 6.5 0.0 2.3 4.2 3.3 0.0 9.1 10.1 3.0 0.0 2.8 6.0 9.8 0.0 1.4 8.1 4.3 6.5 1.4 4.9 10.0 2.4 PDK1 ENSG00000152256 "Pyruvate dehydrogenase kinase 1" Q15118 2 172555373-172608669 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 96.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 5.9;granulocytes: 16.0;T-cells: 15.8" "Cell line enhanced" "Detected in many" "U-266/70: 32.0;U-87 MG: 32.7" "Low region specificity" "Detected in all" "CAB017554, HPA027376" Approved NA NA 22000 "CAB017554: AB_2161138, HPA027376: AB_1855139" "unprognostic (2.14e-1)" "prognostic unfavorable (7.30e-5)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "unprognostic (6.47e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (9.69e-3)" "unprognostic (6.44e-2)" "unprognostic (5.44e-3)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.10e-8)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" "unprognostic (2.56e-2)" "unprognostic (5.34e-2)" 9.9 16.2 6.8 11.0 10.5 13.4 16.7 7.1 15.6 7.3 15.3 3.3 2.9 15.5 5.4 8.0 11.2 4.4 5.8 27.6 6.9 5.2 6.8 14.2 6.1 21.4 7.2 5.2 19.5 7.2 3.4 7.5 7.9 7.2 6.5 13.1 7.6 14.1 7.6 9.6 24.7 8.4 5.2 10.7 14.2 12.5 11.0 6.7 10.3 5.1 5.0 20.8 18.0 9.8 5.9 2.3 16.0 2.2 1.4 15.8 6.2 14.4 0.6 3.7 9.3 1.5 2.3 5.3 12.7 10.3 6.4 13.7 3.7 3.1 13.7 7.0 3.9 5.3 6.3 2.5 7.9 20.5 2.7 5.1 16.7 3.4 4.3 2.7 8.3 6.2 3.0 2.9 4.4 7.5 8.9 3.4 7.3 3.5 9.5 8.4 1.5 5.2 10.4 9.1 2.9 4.0 5.5 6.1 22.1 3.3 4.6 7.0 8.0 3.3 3.9 4.8 3.3 2.5 3.4 3.9 10.2 3.3 5.3 3.4 32.0 18.5 11.3 32.7 6.0 2.0 12.2 2.2 16.0 2.5 1.5 3.0 4.7 4.2 2.8 2.3 5.9 15.8 9.6 8.5 1.4 1.9 0.4 8.0 6.2 6.8 10.5 7.1 15.6 6.9 5.2 7.2 5.2 7.2 6.7 3.0 5.3 32.2 5.4 44.5 26.8 32.3 5.1 1.4 2.3 3.5 45.2 9.1 5.0 7.7 96.0 8.9 6.0 0.0 3.3 9.6 8.4 5.5 5.7 11.9 8.7 52.4 7.5 23.9 12.9 34.3 3.1 8.8 28.7 5.4 5.2 7.6 9.0 14.0 3.5 1.5 18.9 6.5 12.3 6.3 7.7 37.9 3.4 12.5 6.0 2.1 PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 101.0" "Cell type enhanced" "Detected in many" 6 "Proximal tubular cells: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Approved Nucleoplasm,Mitochondria NA NA "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favorable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" 20.6 26.1 17.2 5.2 27.5 3.2 10.8 53.7 34.4 10.1 16.1 16.1 10.1 15.5 13.1 69.8 12.5 14.4 11.5 51.7 18.2 13.0 33.7 27.8 9.0 5.7 14.6 20.9 27.7 24.1 16.9 7.5 8.6 14.2 12.7 12.4 19.5 14.0 16.5 101.0 10.6 16.5 15.1 9.9 7.8 13.6 7.2 11.4 6.2 15.6 31.4 7.4 13.8 9.4 11.3 20.1 8.9 12.9 16.5 17.4 12.2 6.4 9.2 11.1 10.0 11.8 8.9 1.2 7.0 10.4 10.5 10.2 0.8 7.0 8.1 11.7 19.5 7.1 3.1 7.4 2.8 10.3 16.3 10.3 7.2 9.1 6.8 6.3 0.0 7.8 18.7 10.8 6.8 0.5 18.5 9.1 10.4 2.9 8.1 5.9 8.2 6.0 0.0 2.4 19.5 9.0 9.1 24.9 10.9 5.7 5.5 7.4 11.2 9.9 3.1 4.7 14.2 18.3 7.2 4.7 12.3 10.1 8.4 5.1 16.0 15.1 4.4 18.0 2.6 7.9 8.9 12.9 6.8 14.0 9.8 11.1 11.1 12.5 14.8 14.2 11.3 14.6 15.0 2.2 16.5 10.5 20.1 17.4 12.2 17.2 27.5 53.7 34.4 18.2 13.0 14.6 20.9 14.2 11.4 8.9 9.3 13.6 13.9 13.5 20.8 5.0 10.2 1.4 11.4 19.2 5.9 15.1 49.7 8.0 7.3 8.3 46.6 0.0 7.9 3.4 19.5 7.6 1.1 39.8 16.7 41.3 13.3 13.5 13.7 15.0 22.5 7.9 23.6 15.4 45.3 33.6 7.9 43.6 49.5 118.5 9.2 19.4 12.1 3.3 4.4 16.4 6.6 15.8 37.1 8.4 PDK3 ENSG00000067992 "Pyruvate dehydrogenase kinase 3" Q15120 X 24465221-24539837 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease mutation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Early spermatids: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046583, HPA072492" Approved Supported Nucleoli,Mitochondria NA NA Mitochondria Nucleoli "HPA046583: AB_2679707, HPA072492: AB_2686526" "unprognostic (5.41e-3)" "unprognostic (5.43e-3)" "unprognostic (5.35e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-3)" "unprognostic (5.38e-2)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.51e-1)" "unprognostic (5.57e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "unprognostic (1.02e-1)" "unprognostic (2.92e-1)" "unprognostic (2.28e-2)" "unprognostic (9.43e-3)" 9.6 5.6 5.7 9.8 17.3 16.3 12.8 3.3 23.6 8.0 14.7 5.5 5.6 13.6 7.3 15.7 9.5 13.2 7.0 16.9 12.5 6.8 13.7 11.1 11.2 13.4 6.2 13.7 11.0 7.3 12.8 14.1 7.7 14.9 8.3 10.1 9.9 19.3 5.2 3.9 14.2 15.6 8.6 6.1 17.9 12.7 23.1 4.8 12.5 6.2 4.1 14.9 10.3 9.2 4.5 7.2 36.4 10.9 7.1 11.0 6.7 9.0 4.6 3.9 6.6 0.1 0.0 4.1 2.7 2.4 3.7 6.5 0.4 11.1 9.2 1.9 0.7 10.5 2.1 11.3 6.9 10.0 7.8 5.4 4.9 5.3 2.6 1.3 4.2 4.8 0.7 3.1 0.9 0.9 0.4 5.5 9.6 0.9 14.0 0.5 17.0 7.8 5.4 7.0 9.7 5.4 4.0 7.0 13.5 3.2 17.7 2.5 3.2 14.7 6.0 4.6 6.2 8.3 1.6 0.2 2.6 3.8 4.8 3.2 9.0 6.9 11.0 7.1 6.4 5.4 9.4 8.9 21.3 7.6 10.9 11.0 4.5 6.2 6.2 7.2 4.1 4.9 5.7 36.4 7.1 10.4 2.3 5.1 6.7 5.7 17.3 3.3 23.6 12.5 6.8 6.2 13.7 14.9 4.8 3.0 1.3 2.9 8.6 4.0 3.4 6.3 0.0 1.4 2.3 1.8 0.0 4.0 3.3 3.6 53.4 2.8 4.5 0.0 4.5 26.4 3.2 5.2 5.7 4.2 13.2 7.9 4.1 4.3 18.9 22.4 3.4 9.6 15.1 8.2 2.4 3.2 2.8 0.0 5.3 11.3 3.9 0.0 9.2 6.4 6.3 3.9 14.9 14.9 3.3 7.1 PDK4 ENSG00000004799 "Pyruvate dehydrogenase kinase 4" Q16654 7 95583499-95596491 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 351.0;skeletal muscle: 497.0" "Cell type enhanced" "Detected in many" 11 "Cardiomyocytes: 766.1;Collecting duct cells: 359.4;Kupffer cells: 351.0" "Cancer enhanced" "Detected in all" "renal cancer: 107.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 14.2;eosinophil: 15.6;intermediate monocyte: 26.1;myeloid DC: 7.1;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 11 "dendritic cells: 7.1;granulocytes: 15.6;monocytes: 26.1" "Cell line enriched" "Detected in some" 7 "ASC diff: 107.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056731 Approved NA NA "HPA056731: AB_2683218" "unprognostic (3.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (5.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.47e-1)" "unprognostic (6.38e-2)" "unprognostic (2.24e-3)" "unprognostic (1.87e-2)" "unprognostic (8.75e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (9.15e-2)" "unprognostic (4.20e-2)" "unprognostic (1.12e-1)" 90.7 41.9 6.9 5.9 14.6 0.4 49.1 2.5 9.1 12.3 30.9 9.0 150.6 13.6 10.7 13.7 29.0 14.7 15.6 351.0 9.2 3.7 27.7 39.5 14.1 6.1 18.2 2.4 46.6 102.9 0.8 8.1 19.4 26.1 29.3 8.4 4.4 8.4 150.6 497.0 10.2 46.2 20.7 13.9 19.0 21.2 10.8 17.4 1.0 13.4 12.3 2.5 23.8 46.4 0.7 7.1 15.6 26.1 1.4 0.0 4.7 0.0 8.0 0.3 2.0 107.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 1.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.7 0.0 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.1 0.5 0.1 0.6 0.0 0.6 1.6 0.5 0.2 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 14.2 15.6 0.0 26.1 0.0 0.1 0.0 0.0 7.1 0.7 0.0 0.0 1.0 1.4 15.6 0.2 0.0 4.7 6.9 14.6 2.5 9.1 9.2 3.7 18.2 2.4 26.1 17.4 29.8 13.6 12.6 245.0 9.3 0.0 766.1 28.1 96.4 52.4 359.4 0.0 2.7 11.6 4.3 10.2 89.9 112.9 0.0 4.7 0.7 44.7 113.9 4.7 93.7 42.3 0.0 53.1 160.8 351.0 2.5 124.3 29.1 86.0 1.8 47.0 11.6 8.2 42.1 42.1 35.5 0.3 161.7 181.3 0.2 0.5 8.2 9.2 5.7 27.3 131.1 PDPK1 PDK1 ENSG00000140992 "3-phosphoinositide dependent protein kinase 1" O15530 16 2537964-2603188 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004272, HPA035199" Supported Supported Cytosol NA NA Cytosol "CAB004272: AB_626657, HPA035199: AB_2674514" "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (3.12e-3)" "unprognostic (4.21e-2)" "unprognostic (1.34e-1)" "unprognostic (4.69e-3)" "unprognostic (8.37e-2)" "unprognostic (3.18e-2)" "unprognostic (8.17e-2)" "unprognostic (3.70e-2)" "unprognostic (1.52e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.29e-14)" "unprognostic (2.04e-2)" "unprognostic (5.96e-2)" "unprognostic (1.95e-1)" "unprognostic (2.16e-1)" 11.1 14.9 21.0 11.6 31.9 14.2 14.2 29.6 26.4 10.5 15.6 14.5 10.4 17.2 13.0 14.0 13.8 15.3 10.8 14.8 17.2 13.5 17.6 12.6 13.4 13.5 11.3 20.6 14.8 28.2 34.5 13.9 17.1 16.7 13.6 15.3 12.8 16.5 13.2 18.2 14.1 19.1 12.9 10.9 13.7 13.4 14.2 10.1 14.1 16.1 10.6 13.9 12.3 13.3 5.1 9.1 14.7 9.4 5.4 6.0 4.5 8.5 11.0 13.8 9.1 14.2 11.9 14.6 14.3 9.2 12.8 10.8 11.0 10.3 14.1 9.8 13.8 10.9 13.6 16.4 10.3 12.2 25.1 11.1 7.5 14.5 18.2 12.4 12.3 19.7 10.8 19.0 13.8 9.2 12.4 11.7 12.9 13.9 11.5 15.0 18.1 12.4 8.7 8.7 16.0 9.8 25.4 13.7 12.8 12.4 7.7 21.7 11.2 18.5 21.3 7.7 9.2 19.7 15.5 14.3 14.0 13.9 13.6 12.3 15.3 14.6 22.1 6.7 8.6 12.1 3.9 7.9 9.0 5.1 9.3 4.8 5.1 4.7 6.0 6.7 4.5 5.3 4.9 14.7 5.4 9.4 9.1 2.3 4.5 21.0 31.9 29.6 26.4 17.2 13.5 11.3 20.6 16.7 10.1 14.9 18.4 17.1 18.3 23.7 56.0 28.1 43.3 21.4 14.8 10.4 51.1 38.1 11.6 20.5 12.0 15.5 32.9 0.0 20.5 24.1 22.4 24.3 7.0 38.5 22.9 69.9 20.7 23.9 46.7 21.8 29.4 21.5 20.3 30.7 31.7 39.4 25.3 17.5 41.8 34.2 41.5 45.3 18.6 36.7 40.5 29.7 87.5 17.5 27.9 19.6 PEAK1 "KIAA2002, sgk269" ENSG00000173517 "Pseudopodium enriched atypical kinase 1" Q9H792 15 77100656-77420144 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Alveolar cells type 1: 137.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "NK-cell: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026313, HPA026517" Approved NA NA "HPA026313: AB_1856801, HPA026517: AB_1856802" "unprognostic (1.15e-1)" "unprognostic (2.89e-1)" "unprognostic (1.05e-1)" "unprognostic (4.20e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (6.63e-3)" "unprognostic (1.90e-1)" "unprognostic (2.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.06e-1)" "unprognostic (9.75e-2)" "unprognostic (2.25e-3)" "unprognostic (5.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.33e-1)" "unprognostic (5.65e-3)" 21.5 6.0 14.3 8.7 13.2 9.7 12.4 8.4 14.1 15.1 9.3 12.3 6.2 7.2 16.1 8.7 6.6 7.5 12.2 18.5 12.3 7.5 6.6 4.9 20.5 7.5 13.8 8.8 9.8 5.8 7.6 4.2 19.5 9.8 8.4 10.2 13.7 7.0 9.5 8.8 8.4 9.1 14.8 10.1 41.8 6.7 11.5 15.9 2.7 8.3 9.0 5.7 10.0 12.2 0.9 0.6 1.1 0.6 5.5 1.4 0.4 2.6 3.8 9.2 2.1 17.3 18.7 3.2 14.2 9.8 7.6 7.6 3.0 2.3 2.0 2.5 20.4 2.9 1.3 7.3 2.2 8.7 2.0 3.8 3.7 5.7 1.8 6.3 2.2 2.0 14.3 2.2 14.6 2.4 8.3 21.1 3.3 4.8 2.0 8.1 1.0 1.2 2.4 4.2 1.8 1.0 2.5 5.5 1.4 2.2 4.7 2.0 2.5 5.5 1.2 9.5 10.5 0.8 1.5 25.8 16.2 7.8 6.7 6.0 3.2 4.4 2.9 2.8 5.2 8.6 0.4 0.6 1.1 0.7 0.2 1.4 0.9 0.2 0.2 0.3 0.8 0.3 0.3 0.6 5.5 0.2 0.6 0.2 0.4 14.3 13.2 8.4 14.1 12.3 7.5 13.8 8.8 9.8 15.9 137.0 38.5 5.6 7.4 19.5 17.0 40.3 10.2 56.2 45.5 1.8 11.8 2.8 0.0 5.6 12.1 29.4 16.1 0.0 4.7 1.6 38.5 5.2 16.3 3.2 15.1 19.1 2.9 33.2 19.7 10.8 18.4 17.1 11.8 5.4 10.3 31.5 8.3 8.6 15.2 3.1 20.6 12.9 25.0 10.6 11.7 15.7 5.3 5.1 9.7 8.1 PHKG1 PHKG ENSG00000164776 "Phosphorylase kinase catalytic subunit gamma 1" Q16816 7 56080283-56092996 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 105.6;tongue: 32.9" "Cell type enhanced" "Detected in many" 5 "Cholangiocytes: 50.9" "Cancer enriched" "Detected in many" 18 "glioma: 23.6" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012057 Enhanced NA NA "HPA012057: AB_1855305" "unprognostic (2.00e-3)" "unprognostic (1.09e-1)" "unprognostic (7.09e-3)" "unprognostic (5.87e-3)" "unprognostic (2.19e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (6.69e-3)" "unprognostic (2.10e-1)" "unprognostic (1.99e-1)" "unprognostic (9.14e-4)" "unprognostic (1.92e-1)" "unprognostic (7.97e-9)" "unprognostic (6.61e-3)" "unprognostic (2.34e-1)" "unprognostic (1.12e-2)" "unprognostic (3.85e-2)" 2.0 1.5 4.9 0.8 6.1 1.1 1.5 6.0 5.8 0.7 2.6 6.5 0.0 1.0 0.9 1.5 3.2 0.9 1.1 11.8 4.1 2.9 0.6 0.7 0.9 0.8 3.5 3.9 1.0 0.8 1.2 0.6 0.6 6.8 1.4 0.8 0.0 1.6 0.8 105.6 1.6 0.9 1.1 3.6 0.8 0.8 0.7 4.8 0.0 0.6 32.9 1.2 1.8 0.3 1.3 0.6 3.3 0.7 0.3 1.9 0.2 2.9 2.1 0.5 1.8 3.2 5.4 1.4 0.4 0.6 1.0 0.8 0.7 1.3 0.8 0.5 1.0 1.2 1.6 1.2 0.2 0.8 0.8 2.1 0.8 3.0 0.7 0.8 1.5 3.3 3.4 2.3 1.6 0.7 0.8 0.3 2.1 2.2 4.0 0.1 1.3 2.2 5.6 1.0 0.9 1.3 1.2 0.3 1.0 0.6 1.9 1.5 1.6 0.3 2.2 0.1 0.5 1.2 1.9 0.8 0.5 1.7 4.5 1.1 1.8 0.7 2.2 1.2 1.4 1.0 0.4 0.5 0.0 0.8 0.2 1.9 0.3 1.2 0.3 0.2 1.3 0.6 0.6 3.3 0.3 0.7 0.6 0.5 0.2 4.9 6.1 6.0 5.8 4.1 2.9 3.5 3.9 6.8 4.8 11.9 3.4 25.1 6.4 1.1 4.0 1.4 50.9 4.0 6.8 26.2 0.0 6.6 1.7 13.2 2.2 1.4 11.4 23.3 10.9 11.6 6.1 9.6 8.1 41.4 11.0 11.1 16.0 20.9 30.5 5.6 16.7 6.0 1.7 8.2 10.9 4.8 12.7 10.5 15.2 9.0 4.3 12.9 1.0 7.6 9.4 0.9 6.1 8.7 14.4 7.0 PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748270-30761176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood: 44.5;testis: 95.4" "Group enriched" "Detected in many" 6 "Early spermatids: 304.4;Late spermatids: 1171.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol NA NA Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favorable (7.90e-4)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favorable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favorable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" 4.3 8.3 8.7 6.9 8.0 15.9 5.8 9.1 12.0 4.7 7.9 7.3 9.0 6.8 5.6 7.8 5.3 6.8 7.2 6.4 9.0 9.3 8.2 11.0 5.8 6.8 8.6 9.2 4.7 5.1 17.3 8.5 6.3 11.8 7.7 7.6 6.4 7.0 9.9 6.4 8.4 7.3 6.3 5.8 6.9 7.2 95.4 7.3 5.5 8.6 5.5 7.7 5.2 4.7 8.8 21.2 44.5 22.7 23.5 16.8 17.6 13.7 9.0 7.6 9.3 7.1 5.8 17.1 9.6 14.4 13.2 15.1 7.8 6.9 11.9 11.4 9.9 6.7 13.2 7.9 12.2 10.6 6.4 21.9 6.5 15.0 21.8 11.0 10.0 9.3 7.8 6.6 12.6 5.9 6.3 13.4 8.5 8.8 6.9 9.5 31.5 11.8 14.8 10.5 9.9 10.5 16.0 11.9 15.8 15.1 15.5 10.2 7.0 7.8 21.8 9.2 7.2 17.1 8.7 7.9 8.1 9.0 10.1 8.8 13.9 7.5 8.1 16.1 19.6 6.5 14.0 22.7 44.5 16.2 22.4 13.3 8.8 11.6 16.4 21.2 8.5 10.4 12.1 18.2 23.5 15.9 18.2 16.8 17.6 8.7 8.0 9.1 12.0 9.0 9.3 8.6 9.2 11.8 7.3 11.9 23.7 12.6 12.5 18.7 8.9 10.6 2.5 25.4 29.6 17.4 9.8 26.7 23.2 11.4 304.4 9.9 23.2 0.0 21.4 32.3 12.9 24.0 12.7 19.5 25.4 19.1 15.6 9.2 22.4 1171.9 16.1 24.0 11.8 42.3 15.6 9.8 16.8 15.0 21.9 32.7 8.4 0.0 12.5 127.4 23.3 20.1 63.2 26.2 19.6 12.4 PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009985, CAB017804" Approved Supported Mitochondria,Cytosol NA NA Cytosol Mitochondria "CAB017804: , HPA009985: AB_1079610" "unprognostic (1.81e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-3)" "unprognostic (6.49e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-3)" "unprognostic (5.21e-2)" "unprognostic (4.50e-2)" "unprognostic (1.16e-2)" "unprognostic (2.48e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-2)" 20.1 12.3 13.7 11.5 13.4 25.7 22.4 17.1 24.5 12.9 14.0 5.2 5.7 6.5 15.3 7.9 11.6 11.1 13.2 14.2 18.4 9.7 11.7 10.8 13.2 13.8 9.8 15.7 15.4 9.2 24.7 11.6 16.5 16.3 10.7 8.9 7.2 10.9 10.9 15.2 12.0 10.5 12.8 14.4 16.2 10.6 9.3 9.8 29.6 11.0 7.3 13.9 15.1 15.7 6.2 2.6 7.8 3.8 2.4 5.0 1.1 14.6 5.0 8.0 7.4 19.0 22.2 5.9 9.4 12.7 9.3 14.7 4.3 10.9 13.4 16.1 11.2 13.2 6.0 6.6 8.1 13.5 22.4 5.8 18.4 5.5 3.8 9.1 10.3 10.5 14.0 8.6 10.2 11.7 10.4 13.3 9.7 9.1 15.0 13.3 5.8 7.9 9.3 6.4 7.3 6.8 12.0 8.1 16.1 7.3 9.0 4.5 7.7 10.2 9.1 12.2 7.3 15.2 8.9 14.0 8.7 5.7 13.7 9.3 7.3 10.3 24.1 7.9 7.8 5.1 2.1 3.8 1.6 5.0 2.9 3.9 5.8 4.2 2.8 2.2 6.2 4.6 3.8 7.8 2.4 3.0 2.6 4.1 1.1 13.7 13.4 17.1 24.5 18.4 9.7 9.8 15.7 16.3 9.8 29.8 23.2 13.7 15.2 13.1 26.3 15.4 7.6 18.7 17.0 7.0 29.5 8.1 1.7 9.8 1.7 21.4 4.9 0.0 11.9 5.0 18.3 27.3 30.1 17.4 9.5 36.5 2.4 29.4 21.2 1.6 30.2 16.4 13.5 16.2 9.6 15.6 13.1 12.7 37.1 11.2 26.2 25.8 22.1 9.6 7.6 13.0 7.3 14.0 9.2 27.6 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106907145 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 24.5;bone marrow: 27.8;lymphoid tissue: 40.8" "Cell type enhanced" "Detected in some" 8 "B-cells: 17.3;Early spermatids: 26.6;granulocytes: 19.7;monocytes: 24.4;T-cells: 17.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 12.4;HL-60: 12.1;HMC-1: 15.5;Karpas-707: 12.9;MOLT-4: 23.5;U-266/70: 31.5;U-937: 22.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Plasma membrane" Cytosol "HPA069976: AB_2686224" "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 5.0 1.8 2.2 16.0 3.1 27.8 2.3 0.8 1.7 1.7 4.1 2.7 0.0 2.8 1.7 2.0 2.0 1.8 3.5 1.7 1.7 1.5 1.9 1.5 4.3 13.1 3.0 1.0 1.7 1.5 0.6 1.4 2.0 2.5 2.2 2.6 1.9 3.1 0.5 1.1 1.3 6.1 1.9 6.4 17.4 2.5 7.6 3.0 40.8 2.3 0.9 21.2 4.1 1.5 6.2 5.6 14.2 24.5 5.3 5.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.6 0.0 0.0 0.0 12.1 15.5 0.0 0.0 0.0 0.0 0.0 4.8 7.4 8.6 12.9 0.0 0.0 23.5 4.6 0.0 0.0 0.0 6.2 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 1.2 0.0 0.1 0.0 0.0 31.5 0.0 11.7 0.0 22.2 2.9 4.6 3.4 14.2 5.6 10.6 5.1 4.7 2.6 4.2 5.6 6.2 2.8 3.8 13.9 5.3 24.5 4.9 2.6 3.6 2.2 3.1 0.8 1.7 1.7 1.5 3.0 1.0 2.5 3.0 0.0 2.6 17.3 0.0 0.7 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 26.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 19.7 0.5 5.9 0.0 0.0 1.8 11.0 12.8 0.6 13.3 6.8 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 3.1 0.3 0.1 17.5 0.0 0.0 PIK3R4 "p150, VPS15" ENSG00000196455 "Phosphoinositide-3-kinase regulatory subunit 4" Q99570 3 130678935-130746829 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036032, HPA036033" Approved Approved Vesicles,Microtubules NA NA Vesicles Microtubules "HPA036032: AB_10610281, HPA036033: AB_2674911" "unprognostic (7.50e-2)" "unprognostic (3.90e-3)" "unprognostic (1.68e-1)" "unprognostic (4.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (1.02e-3)" "unprognostic (7.26e-2)" "prognostic favorable (4.40e-6)" "unprognostic (8.25e-2)" "unprognostic (3.72e-1)" "unprognostic (2.27e-1)" "unprognostic (1.05e-1)" 15.5 16.2 11.6 11.6 15.9 10.6 14.9 14.7 17.2 16.5 13.1 14.9 9.5 10.3 18.8 12.0 12.9 15.6 12.0 12.2 9.7 10.0 14.9 28.2 13.7 12.4 12.0 11.4 17.8 12.0 40.7 20.6 14.4 17.3 14.1 11.6 14.1 14.0 15.4 14.8 16.0 13.4 14.6 12.1 18.5 13.3 14.9 11.8 29.7 18.1 10.2 13.6 16.5 13.9 8.4 9.6 12.0 8.5 11.5 13.7 7.0 14.3 9.1 13.4 9.7 19.9 15.9 9.3 10.7 12.9 14.8 17.2 11.8 12.2 16.9 13.5 10.8 11.8 20.6 22.0 16.6 23.3 10.2 8.2 13.8 10.5 8.2 9.1 20.9 6.9 10.9 12.0 15.8 10.0 9.3 13.7 9.9 16.0 8.6 13.0 12.6 17.1 6.4 16.9 13.0 9.0 12.0 15.6 15.2 9.7 11.8 12.4 9.1 15.4 9.7 10.8 16.5 13.4 9.2 10.8 11.4 9.9 12.8 8.5 10.1 9.1 22.3 12.5 8.0 10.5 12.0 7.2 9.2 9.4 8.4 13.7 8.4 8.6 6.9 9.6 5.7 10.1 9.0 6.0 11.5 8.5 3.4 9.3 7.0 11.6 15.9 14.7 17.2 9.7 10.0 12.0 11.4 17.3 11.8 6.0 5.4 0.0 3.4 3.4 8.2 7.5 15.3 14.7 11.4 10.4 13.7 4.6 1.7 4.1 3.4 6.7 5.3 0.0 5.1 3.1 3.5 3.7 9.2 15.6 5.1 4.8 2.9 8.0 6.7 2.7 8.9 3.8 5.0 5.4 6.2 8.0 5.3 5.8 11.0 4.9 12.0 6.5 3.2 10.8 12.7 3.9 3.5 4.6 5.8 2.5 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170203-37175426 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Suprabasal keratinocytes: 199.7;Urothelial cells: 399.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "basophil: 64.6" "Group enriched" "Detected in all" 5 "granulocytes: 64.6;T-cells: 19.0" "Cell line enhanced" "Detected in many" "HEL: 35.7;HMC-1: 66.4;K-562: 30.6;U-698: 119.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoli,Cytosol NA NA Cytosol Nucleoli "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 39.3 5.4 7.4 18.5 8.9 80.9 20.1 8.1 9.9 23.0 17.9 4.7 4.2 17.9 15.4 9.8 56.3 21.6 24.7 20.8 8.2 3.7 7.5 24.5 14.5 35.7 7.4 2.2 20.0 9.6 2.0 5.6 28.7 12.7 15.6 8.8 6.9 12.8 4.5 26.5 31.3 26.1 31.6 10.7 21.4 12.1 6.8 7.6 15.0 7.2 20.1 28.8 32.6 31.2 1.7 1.4 64.6 1.7 8.4 19.0 8.5 3.0 1.3 2.0 1.1 4.7 2.5 24.0 1.1 3.4 2.3 3.6 4.6 4.3 6.2 1.7 1.3 5.1 3.6 2.1 3.3 2.1 28.1 1.4 35.7 1.3 5.9 4.8 0.6 66.4 8.5 4.1 2.1 1.4 2.5 0.6 1.5 30.6 10.0 0.3 0.8 1.9 3.2 3.8 5.7 2.0 4.8 3.7 7.3 0.6 18.8 10.0 2.0 2.4 0.3 0.6 4.9 0.5 1.0 1.2 1.3 4.0 6.0 1.3 4.7 2.5 119.4 0.5 9.0 1.3 64.6 1.7 24.4 14.7 1.6 19.0 1.7 13.1 12.9 1.4 1.3 11.9 9.0 14.1 8.4 0.9 0.4 9.4 8.5 7.4 8.9 8.1 9.9 8.2 3.7 7.4 2.2 12.7 7.6 20.8 23.1 27.2 134.9 113.6 4.2 17.3 12.7 4.0 22.7 8.7 0.0 27.3 5.0 30.7 3.8 14.3 33.2 46.7 15.5 92.9 73.9 69.5 46.4 27.1 44.8 14.3 35.6 9.2 40.0 10.4 7.5 45.8 42.2 101.0 11.9 4.3 37.7 17.5 2.8 13.0 0.9 0.0 57.5 3.3 34.5 199.7 67.5 126.4 6.6 399.5 PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood: 63.4;lymphoid tissue: 71.2" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 48.0;B-cells: 109.2;Melanocytes: 89.4;monocytes: 163.3;T-cells: 70.8" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HDLM-2: 60.3;Karpas-707: 74.7;RPMI-8226: 73.6;U-266/70: 136.0;U-266/84: 120.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol NA NA Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favorable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" 3.6 3.4 4.3 37.2 7.2 30.4 3.4 7.1 7.9 4.5 13.4 2.1 2.2 29.5 2.8 4.3 10.0 5.6 8.3 3.1 5.6 6.7 5.2 5.4 10.6 59.7 3.8 4.6 5.4 3.0 1.0 4.9 2.4 6.7 3.6 17.7 6.1 16.9 4.9 1.5 3.0 19.2 2.2 3.1 71.2 14.7 5.7 1.3 39.4 4.8 3.6 47.9 24.6 3.3 26.0 2.9 46.9 3.0 17.0 63.4 13.2 1.8 1.6 0.8 1.7 0.3 0.2 1.3 1.1 1.4 1.6 1.4 1.4 1.4 8.0 0.5 0.5 0.6 1.1 2.7 1.0 1.5 60.3 2.1 9.7 1.6 1.4 0.7 2.3 6.5 0.6 0.9 1.7 1.0 1.3 0.6 1.0 10.2 74.7 0.9 1.3 0.8 4.8 18.2 0.6 2.5 1.0 0.6 73.6 1.6 0.2 0.6 0.8 1.2 0.8 0.8 4.3 2.1 3.1 0.3 0.4 0.2 0.3 1.1 136.0 120.2 15.3 1.5 2.0 0.4 46.9 1.5 14.3 12.5 1.9 21.2 26.0 34.4 17.6 2.5 15.9 36.9 23.0 38.3 17.0 3.0 2.9 63.4 13.2 4.3 7.2 7.1 7.9 5.6 6.7 3.8 4.6 6.7 1.3 11.9 48.0 109.2 9.5 18.0 2.3 2.0 0.0 14.7 12.5 3.5 2.0 5.3 3.3 2.8 1.4 4.3 4.0 0.0 3.1 5.0 7.5 4.0 22.0 5.4 6.3 11.1 12.6 3.1 9.1 1.4 1.7 18.6 89.4 163.3 6.6 2.3 1.6 3.5 3.9 5.4 2.2 0.0 8.1 2.1 1.5 12.0 2.1 70.8 8.1 3.9 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960513-49964080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Syncytiotrophoblasts: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 16.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 46.5;SK-BR-3: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol NA Yes Cytosol "HPA068758: AB_2686026" "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 32.5 15.5 6.8 19.9 16.7 62.4 50.5 7.6 11.9 16.4 22.6 11.3 20.9 15.9 14.4 17.6 25.0 15.9 37.8 23.6 7.5 7.9 29.1 25.7 38.3 29.4 21.1 4.9 13.9 36.4 4.8 14.9 31.4 15.1 28.4 7.6 9.7 27.6 22.7 39.9 31.3 20.9 12.2 10.1 25.4 33.6 13.0 13.5 9.7 19.1 19.9 19.0 25.6 18.3 6.1 5.7 16.9 4.0 1.2 4.5 1.9 7.3 4.9 3.3 6.2 2.6 1.9 18.9 4.6 7.5 5.6 4.0 8.1 6.3 13.2 5.9 1.2 11.3 6.3 6.3 3.5 2.0 9.9 26.2 5.4 11.7 9.8 12.2 11.7 10.5 3.7 11.7 3.4 5.8 3.0 18.0 9.0 7.4 46.5 1.6 16.5 5.9 20.9 6.9 7.7 7.9 27.7 5.5 15.6 2.9 5.6 11.8 8.2 9.0 41.3 28.9 3.2 5.4 15.6 4.7 3.5 15.0 5.7 7.5 23.9 15.2 11.2 8.7 6.6 9.4 0.0 3.1 0.1 1.9 3.2 2.3 3.4 4.4 3.8 2.5 6.1 4.1 1.7 16.9 1.2 4.0 5.7 4.5 1.9 6.8 16.7 7.6 11.9 7.5 7.9 21.1 4.9 15.1 13.5 59.6 91.3 64.7 240.2 201.8 30.4 27.9 68.8 20.1 45.5 76.8 2.0 51.0 71.3 44.7 2.1 87.2 56.5 0.0 46.7 226.7 51.4 225.9 70.2 37.5 64.3 58.8 93.7 59.5 30.8 4.1 30.0 74.6 102.9 46.9 56.5 11.1 57.1 46.3 10.6 48.8 15.3 25.8 117.4 19.9 37.3 178.9 326.1 26.6 49.6 261.0 PINK1 PARK6 ENSG00000158828 "PTEN induced putative kinase 1" Q9BXM7 1 20633455-20651511 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Parkinson disease, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 142.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 10.7" "Group enriched" "Detected in many" 4 "granulocytes: 10.7;monocytes: 4.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001931, CAB026191" Enhanced NA NA "CAB026191: , HPA001931: AB_1079620" "unprognostic (3.73e-3)" "unprognostic (2.29e-2)" "unprognostic (3.22e-1)" "unprognostic (4.33e-2)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-2)" "unprognostic (3.36e-2)" "unprognostic (3.51e-2)" "unprognostic (4.06e-3)" "unprognostic (3.34e-2)" "unprognostic (2.54e-1)" "prognostic favorable (1.11e-16)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (6.57e-2)" "unprognostic (1.08e-1)" 17.9 35.9 38.9 6.7 38.0 6.0 10.1 16.8 45.0 9.8 13.0 17.8 10.0 15.2 9.3 9.8 20.7 10.7 11.4 51.4 31.0 28.7 20.2 26.1 10.0 5.1 39.5 27.1 11.6 24.3 16.3 7.1 13.9 31.0 12.4 7.7 10.6 23.9 15.4 142.0 10.8 12.7 10.8 30.2 8.3 10.5 27.2 16.8 3.3 16.0 21.5 4.6 12.7 9.5 1.2 1.4 10.7 4.4 0.7 1.7 0.8 17.7 8.1 3.8 11.0 13.3 12.6 4.0 25.1 25.2 12.2 21.3 2.8 14.5 4.2 19.9 25.5 28.4 8.2 5.5 13.3 6.1 5.0 21.0 2.1 22.7 4.3 10.3 2.2 6.7 11.8 14.4 15.2 5.3 13.7 7.9 3.9 5.1 5.4 8.7 7.5 3.2 5.0 1.7 4.6 26.8 2.8 6.7 3.3 7.6 4.2 14.2 5.5 27.3 9.0 7.6 4.8 3.0 7.8 11.9 11.0 5.7 18.4 3.5 6.3 1.2 1.9 23.9 6.4 5.1 4.8 2.2 4.7 1.1 1.4 1.4 0.3 1.0 1.5 0.7 1.2 0.8 1.1 10.7 0.7 4.4 1.4 1.7 0.8 38.9 38.0 16.8 45.0 31.0 28.7 39.5 27.1 31.0 16.8 20.8 16.3 7.5 31.9 14.0 40.7 0.8 28.1 1.4 6.8 41.8 35.3 21.6 68.0 22.2 58.2 29.5 63.2 23.3 24.0 29.3 21.6 60.4 0.0 92.6 20.3 27.0 19.3 46.6 19.9 102.1 32.8 20.6 20.3 4.6 26.4 52.6 41.8 45.6 53.4 91.3 57.1 84.1 37.3 110.5 24.5 21.0 28.6 13.1 18.0 30.8 PKDCC "SgK493, Vlk" ENSG00000162878 "Protein kinase domain containing, cytoplasmic" Q504Y2 2 42048020-42058528 "Enzymes, Predicted secreted proteins" "Differentiation, Osteogenesis, Protein transport, Transport" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Intestinal endocrine cells: 69.1;Leydig cells: 127.4;Peritubular cells: 105.4;Rod photoreceptor cells: 93.6;Undifferentiated cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 31.2;ASC diff: 24.8;CACO-2: 36.9;HHSteC: 21.3;RH-30: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026427, HPA026442, HPA026526" Approved "Secreted to blood" NA NA 10000 "HPA026427: AB_10600773, HPA026442: AB_10601237, HPA026526: AB_10602416" "unprognostic (6.77e-2)" "unprognostic (3.35e-1)" "unprognostic (1.04e-2)" "unprognostic (3.59e-3)" "unprognostic (8.31e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (5.79e-3)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (2.14e-2)" "unprognostic (9.08e-2)" "unprognostic (2.62e-1)" "unprognostic (4.73e-3)" "unprognostic (2.58e-3)" 21.4 5.7 1.9 8.4 1.8 0.8 18.9 0.3 4.7 20.8 13.7 1.7 6.3 9.3 17.6 16.0 9.2 10.0 29.6 17.0 2.3 0.7 4.7 3.5 8.0 3.7 3.7 0.3 43.6 3.3 0.9 3.2 3.2 2.6 13.0 5.2 17.0 38.6 5.6 40.2 1.7 7.7 26.2 2.3 4.6 4.8 14.1 2.3 4.2 3.1 13.1 2.1 22.8 23.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 2.0 5.5 31.2 24.8 0.3 2.0 0.1 0.0 0.4 0.6 36.9 0.0 0.0 0.1 0.6 0.7 0.0 0.5 0.0 0.0 3.0 1.3 0.0 1.3 9.8 21.3 0.0 0.4 2.1 0.1 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.1 0.1 0.0 0.1 9.1 2.5 0.6 0.0 10.8 0.0 0.0 0.0 1.1 1.9 0.5 0.0 0.0 6.7 0.0 0.2 0.0 0.2 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.3 4.7 2.3 0.7 3.7 0.3 2.6 2.3 17.9 0.3 0.5 0.2 2.9 2.1 8.1 2.5 0.0 0.0 1.8 15.7 0.4 0.0 1.8 1.1 1.9 11.8 0.0 1.2 1.2 21.1 0.9 0.0 2.6 0.6 0.0 69.1 3.7 0.3 2.6 127.4 0.2 1.7 0.0 11.8 20.3 1.2 14.0 105.4 3.2 93.6 12.9 8.5 0.5 1.2 1.6 0.2 0.0 34.2 0.1 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980539 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 19.5;lymphoid tissue: 42.8;testis: 61.4" "Group enriched" "Detected in many" 6 "Extravillous trophoblasts: 39.8;Spermatocytes: 108.0;Spermatogonia: 40.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 5 "T-reg: 4.4" "Lineage enriched" "Detected in single" 5 "T-cells: 4.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 0.9 0.7 0.7 9.4 0.6 19.5 1.3 2.6 0.8 1.3 2.9 0.3 0.5 1.9 0.8 1.5 7.2 0.2 1.5 1.4 0.7 0.7 0.8 1.0 1.3 6.2 0.8 0.2 0.3 1.3 0.0 0.7 4.3 0.4 0.6 0.8 0.3 1.3 0.2 1.6 3.4 3.2 0.6 1.0 4.4 2.7 61.4 0.2 42.8 0.3 9.2 12.7 0.7 2.0 0.8 0.4 0.3 0.5 0.4 4.4 1.0 24.9 17.5 6.8 9.8 0.1 0.3 18.6 19.4 4.6 12.3 11.8 13.6 14.8 15.6 8.7 2.1 7.3 32.1 4.8 6.2 2.2 20.0 15.7 7.9 15.8 11.9 0.0 8.8 22.5 0.2 0.5 7.3 2.0 1.5 2.5 17.3 22.7 27.7 4.0 37.4 24.6 24.5 11.2 11.7 9.3 26.9 15.3 30.2 2.3 5.5 13.0 13.8 9.4 24.5 7.3 3.9 14.0 17.6 2.3 16.6 21.0 24.2 20.3 21.0 15.6 26.8 6.3 11.8 19.2 0.0 0.4 0.3 0.3 0.3 0.0 0.8 0.5 0.5 0.4 0.0 0.0 0.0 0.1 0.4 0.5 0.1 4.4 1.0 0.7 0.6 2.6 0.8 0.7 0.7 0.8 0.2 0.4 0.2 0.0 1.4 0.0 0.8 2.3 0.1 0.4 2.5 0.0 2.3 1.8 5.9 3.0 0.0 1.1 11.2 0.3 0.2 0.0 0.5 39.8 0.4 0.5 0.0 0.2 10.2 0.0 1.7 0.0 1.3 7.5 0.3 1.3 0.0 1.0 1.2 0.3 0.3 0.0 0.4 0.0 6.7 0.0 0.0 108.0 40.5 0.5 6.2 0.7 3.5 0.4 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Approved "Plasma membrane,Focal adhesion sites,Cytokinetic bridge" NA NA "Plasma membrane" "Focal adhesion sites, Cytokinetic bridge" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 28.8 19.5 19.1 27.6 26.7 39.6 25.3 21.9 19.2 19.2 26.0 20.9 16.5 10.0 25.4 19.7 16.6 22.2 22.5 38.3 17.1 17.6 17.9 16.3 27.9 42.2 19.5 16.3 21.7 32.3 15.8 18.7 22.7 19.2 22.6 6.9 21.5 22.6 22.7 43.2 7.6 16.9 22.5 19.4 39.7 24.2 21.5 18.9 39.2 17.8 13.8 24.0 22.1 30.5 11.5 17.0 24.1 30.6 13.5 20.7 15.2 37.7 22.5 8.4 17.4 13.6 16.1 13.8 13.6 16.3 14.4 13.8 8.8 21.7 36.1 35.2 23.3 18.0 8.8 13.4 6.0 5.6 29.2 17.4 43.2 14.4 18.6 45.1 17.0 27.1 11.5 4.4 8.7 13.7 16.4 33.4 19.2 19.1 25.1 10.6 15.5 25.5 15.7 15.2 13.7 25.8 34.3 11.5 25.9 7.1 6.2 30.6 43.4 8.4 10.8 22.0 4.2 9.7 29.6 49.9 28.6 12.3 34.6 20.6 33.0 30.0 19.7 18.8 34.1 22.4 15.4 17.3 24.1 20.7 24.2 15.7 10.7 14.0 14.2 17.0 11.5 13.1 14.3 21.3 13.5 30.6 11.1 15.9 15.2 19.1 26.7 21.9 17.3 17.1 17.6 19.5 16.3 19.2 18.9 3.0 2.1 24.5 5.5 3.3 36.7 3.5 25.5 1.4 1.2 33.2 15.7 1.9 1.7 23.7 4.1 29.5 2.6 0.0 25.6 12.9 16.0 10.2 2.3 9.6 49.5 46.1 38.6 51.0 56.2 6.7 18.4 27.1 16.9 29.7 12.0 47.4 49.8 9.5 21.5 12.7 25.3 25.8 16.5 6.3 26.6 2.4 3.1 48.4 6.6 3.2 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "neutrophil: 35.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 35.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: AB_2674363, HPA057913: AB_2732617" "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 21.9 20.7 12.2 21.2 13.7 33.5 27.6 25.6 16.6 28.6 39.3 12.6 15.1 22.9 20.0 20.2 28.2 17.1 13.3 16.2 10.3 8.9 15.9 15.9 26.0 16.4 13.7 8.7 27.2 18.9 24.6 29.7 20.8 13.3 19.6 23.6 14.1 19.5 25.1 15.9 17.5 49.0 17.5 12.5 18.0 15.9 12.4 16.2 29.1 20.3 14.4 13.1 21.9 22.0 4.0 3.7 35.7 4.5 1.4 3.0 1.0 23.7 9.3 18.5 11.1 12.4 14.1 12.0 14.1 13.0 15.8 16.5 9.9 17.1 9.4 16.8 13.4 19.5 18.8 18.0 10.7 21.7 3.3 13.1 6.9 19.4 8.4 10.9 6.8 2.1 11.6 11.1 12.4 15.0 12.6 18.0 7.5 11.5 6.9 17.0 4.8 7.8 5.9 9.3 9.0 10.9 7.5 28.2 3.8 14.0 46.8 9.0 5.9 21.1 12.2 18.1 14.6 9.1 6.2 16.8 13.5 12.1 17.2 14.7 3.8 3.2 6.4 5.6 6.7 5.0 4.9 4.5 6.8 2.6 2.5 2.3 3.3 2.3 2.4 2.1 4.0 3.0 2.6 35.7 1.4 3.2 3.7 1.8 1.0 12.2 13.7 25.6 16.6 10.3 8.9 13.7 8.7 13.3 16.2 38.7 52.6 24.5 42.6 42.9 83.6 41.1 40.8 45.5 39.8 66.3 84.4 37.5 10.0 51.4 2.1 51.2 79.8 70.0 52.5 29.4 35.1 52.3 15.1 32.6 20.4 62.0 42.5 51.0 34.3 2.9 50.3 29.0 30.4 41.5 55.9 64.3 62.0 87.7 45.3 22.4 151.6 38.8 29.8 35.8 18.8 45.8 31.2 21.0 50.9 118.4 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702523-128720918 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Endothelial cells: 13.4;Extravillous trophoblasts: 5.1;Ito cells: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 33.4;REH: 20.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA Vesicles "HPA045390: AB_2679308, HPA058305: AB_2683674" "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 11.4 1.8 1.5 6.8 3.8 3.7 10.5 10.1 3.9 4.3 5.8 3.7 4.8 7.7 9.7 2.2 7.1 5.3 10.9 7.3 2.3 1.7 5.0 6.4 8.9 9.1 3.9 1.2 4.0 4.2 3.3 1.4 5.6 4.5 4.2 1.6 4.1 12.9 3.7 7.4 6.7 5.4 4.9 4.4 7.8 7.4 4.3 1.7 9.3 8.1 6.1 5.9 4.4 5.0 0.4 1.0 2.3 0.7 1.0 1.8 0.3 1.4 6.9 5.6 8.5 0.0 0.1 13.9 4.3 1.3 6.3 6.5 0.0 5.0 0.0 4.2 2.3 1.3 9.3 6.8 1.0 1.4 4.3 12.8 8.2 33.4 9.7 1.0 1.0 1.5 0.3 0.3 3.4 0.9 1.3 12.4 2.5 18.6 0.9 1.1 12.8 1.2 4.4 5.2 6.3 2.0 20.3 10.6 1.8 2.6 0.8 0.9 4.2 3.2 1.7 3.2 3.2 6.1 6.6 10.7 0.0 5.3 9.9 3.2 3.1 1.3 2.7 0.8 1.0 3.9 0.0 0.1 1.4 0.9 0.7 1.8 0.2 0.6 0.8 1.0 0.4 0.8 0.1 2.3 1.0 0.2 0.2 1.0 0.3 1.5 3.8 10.1 3.9 2.3 1.7 3.9 1.2 4.5 1.7 0.0 1.3 0.0 1.4 0.9 0.0 1.5 0.0 0.0 2.3 0.0 0.0 1.2 0.0 1.6 0.3 13.4 1.1 0.0 2.3 5.1 0.9 0.9 0.0 0.2 1.5 0.0 0.0 6.2 0.3 0.4 1.4 0.2 0.0 1.8 1.0 0.5 2.6 0.8 0.7 0.3 0.2 0.0 0.8 1.0 3.4 0.9 1.1 1.0 1.4 1.6 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 83.9;testis: 32.4" "Cell type enhanced" "Detected in many" 18 "Early spermatids: 86.9;Erythroid cells: 23.3;Extravillous trophoblasts: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "T-reg: 9.0" "Lineage enriched" "Detected in many" 5 "T-cells: 9.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA051638, HPA053229" Approved NA Yes "HPA051638: AB_2681561, HPA053229: AB_2682084" "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (2.70e-7)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 2.9 1.1 1.1 14.2 1.5 15.9 1.7 2.1 1.1 1.5 7.1 0.7 0.5 6.0 1.1 0.9 10.4 0.7 1.5 1.0 1.0 0.8 1.3 1.2 2.6 15.2 0.8 0.6 1.2 0.7 0.0 0.8 6.8 0.7 0.9 5.9 0.5 1.7 0.8 0.8 2.9 5.9 2.0 0.7 8.3 3.6 32.4 0.5 83.9 0.6 6.6 20.4 2.1 2.6 1.9 0.5 0.7 0.1 1.3 9.0 2.3 43.5 45.5 37.6 20.4 1.1 2.6 21.1 24.9 16.5 39.1 29.1 39.7 28.8 21.8 13.0 16.8 20.6 25.1 51.2 20.5 47.1 31.0 28.9 27.7 35.9 54.2 0.3 31.9 30.4 1.0 1.1 27.7 28.6 4.9 28.5 28.6 43.0 30.1 30.1 39.8 30.1 31.9 42.9 17.9 23.2 46.9 25.5 34.6 11.1 9.5 21.2 14.7 28.5 20.0 12.9 22.4 25.4 19.7 14.4 18.6 23.8 18.2 42.5 21.5 33.3 37.8 15.8 27.8 30.4 0.0 0.1 0.0 0.0 0.0 0.0 1.9 1.4 0.5 0.5 0.0 0.0 0.0 0.7 1.3 0.0 0.0 9.0 2.3 1.1 1.5 2.1 1.1 1.0 0.8 0.8 0.6 0.7 0.5 3.0 0.0 0.8 1.0 1.1 1.3 0.6 0.0 0.0 0.0 0.0 3.9 4.5 0.0 0.6 86.9 0.5 1.5 23.3 0.7 48.0 0.7 1.0 1.1 0.9 17.0 0.0 0.0 3.1 3.7 4.8 1.1 2.6 0.0 0.0 2.9 1.1 0.8 0.0 0.7 0.0 1.1 0.0 0.3 3.2 5.0 1.6 3.2 1.3 3.9 1.8 PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460260 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Extravillous trophoblasts: 180.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cell: 10.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 147.8;T-47d: 51.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: AB_2167745, HPA069329: " "unprognostic (4.82e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.75e-4)" "unprognostic (1.22e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (2.44e-2)" "unprognostic (1.06e-2)" "unprognostic (1.01e-1)" "unprognostic (3.11e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (6.56e-2)" "unprognostic (1.43e-1)" "unprognostic (3.46e-1)" "unprognostic (1.95e-3)" 11.4 3.7 19.6 4.0 40.2 4.4 23.4 1.3 39.4 20.6 5.7 3.7 5.0 5.1 19.2 7.1 17.7 9.5 18.2 28.1 18.8 5.1 6.9 17.6 17.7 3.8 4.2 20.6 11.8 12.6 3.8 3.3 25.9 8.7 8.7 8.7 12.6 22.1 6.2 8.7 20.9 6.1 15.4 2.7 54.7 4.7 19.8 7.4 1.0 8.9 16.6 7.5 14.2 15.5 1.2 2.9 3.0 1.6 10.4 1.2 0.6 16.4 14.9 5.2 0.4 2.7 4.5 2.0 3.5 5.9 11.7 6.8 1.1 14.6 0.0 23.2 12.6 28.5 20.7 0.2 8.1 10.7 0.0 0.4 0.0 6.7 1.2 14.8 0.0 0.4 2.6 11.3 4.5 12.7 147.8 23.5 0.0 0.0 0.5 23.1 6.0 0.0 0.0 0.9 1.6 2.4 0.8 14.3 0.0 30.8 3.3 0.3 0.7 10.8 2.1 9.5 9.7 51.9 0.2 30.0 3.2 8.7 1.4 28.1 0.0 0.0 0.0 2.5 0.0 14.4 3.0 0.7 2.3 0.1 1.6 0.0 1.2 0.7 0.0 2.9 0.9 1.2 0.6 1.9 10.4 0.6 2.0 0.5 0.6 19.6 40.2 1.3 39.4 18.8 5.1 4.2 20.6 8.7 7.4 17.9 18.6 2.7 128.0 125.8 2.8 105.2 22.9 18.7 68.2 17.4 3.9 55.6 8.3 96.4 5.7 109.7 37.3 0.0 69.2 180.6 32.4 45.1 9.2 6.0 13.5 0.0 80.9 51.5 8.9 2.3 11.8 11.2 23.6 5.4 25.3 3.5 71.6 40.7 10.3 2.5 2.7 0.0 79.3 72.4 10.4 90.5 108.6 6.4 24.3 54.0 PLK3 "CNK, FNK, PRK" ENSG00000173846 "Polo like kinase 3" Q9H4B4 1 44800225-44805990 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060318 Enhanced NA NA "HPA060318: AB_2684252" "unprognostic (1.06e-1)" "unprognostic (8.71e-2)" "unprognostic (3.69e-2)" "unprognostic (3.51e-3)" "unprognostic (3.09e-2)" "unprognostic (4.72e-2)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (5.12e-3)" "unprognostic (6.78e-2)" "unprognostic (7.67e-3)" "unprognostic (2.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" 14.8 7.6 4.4 16.3 18.8 8.6 10.0 2.4 6.4 8.6 5.3 13.9 3.2 4.0 9.9 5.8 23.9 8.5 21.6 6.8 10.5 6.0 6.7 9.0 14.9 10.0 9.9 2.5 7.8 10.7 15.6 9.0 29.6 14.8 6.4 4.0 7.6 8.2 6.8 7.0 16.6 7.0 6.0 15.2 9.1 6.1 4.5 5.6 4.6 8.4 25.0 18.2 9.9 9.5 1.3 4.2 2.8 5.1 0.6 11.0 3.5 4.1 2.7 4.2 1.9 3.1 10.1 7.8 9.7 13.7 3.7 3.7 1.6 5.8 5.0 4.1 7.9 12.0 3.7 2.3 13.2 2.1 8.1 0.7 5.6 1.5 3.6 15.2 1.8 7.2 7.9 8.0 11.0 10.8 12.9 11.6 1.8 2.8 2.1 8.3 2.7 3.7 1.6 2.8 2.5 3.3 4.4 2.8 7.3 13.2 1.5 3.2 2.0 2.6 4.5 10.7 6.7 0.4 1.7 14.8 2.3 5.7 4.5 5.7 5.8 2.7 1.3 4.9 2.9 4.5 0.0 2.9 0.8 1.7 5.0 2.1 1.3 9.9 4.2 4.2 1.1 11.0 4.9 2.8 0.6 5.1 1.8 10.5 3.5 4.4 18.8 2.4 6.4 10.5 6.0 9.9 2.5 14.8 5.6 11.9 41.5 19.3 51.6 39.2 5.3 2.2 12.7 9.4 12.5 5.2 2.0 13.1 0.0 17.7 0.6 29.7 73.5 0.0 11.3 19.2 25.9 18.8 78.3 5.4 35.4 6.4 50.8 24.5 18.9 0.4 9.2 52.8 11.8 10.8 21.9 5.4 18.2 66.6 4.9 2.3 9.6 25.8 26.8 1.7 4.9 29.4 49.5 24.5 28.1 55.0 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880861-127899195 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.5;lymphoid tissue: 21.7;testis: 21.7" "Cell type enhanced" "Detected in many" 14 "Early spermatids: 48.9;Erythroid cells: 23.3;Late spermatids: 60.1;Spermatocytes: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol NA NA "Centrosome, Cytosol" "HPA017327: AB_2669584, HPA035026: AB_10602080, HPA043198: AB_2732504" "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favorable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.4 1.3 1.5 4.7 2.4 16.5 2.2 0.5 2.2 2.0 3.2 0.3 0.6 2.3 1.3 1.3 5.4 1.1 1.2 2.0 1.2 1.3 1.5 0.9 1.5 5.9 1.2 1.4 1.5 0.9 0.3 0.6 5.0 2.6 1.4 3.7 0.8 1.7 0.7 0.4 2.7 3.2 1.9 1.8 2.7 1.6 21.7 1.0 21.7 1.0 2.1 6.0 1.5 2.2 0.7 0.7 1.5 0.8 1.4 4.0 0.8 11.8 5.6 21.1 10.8 0.7 2.1 9.6 11.6 8.2 15.5 16.0 7.8 12.2 16.0 4.3 6.4 12.6 7.8 14.8 9.3 23.9 12.4 6.1 14.5 9.0 7.3 0.2 20.4 17.1 0.6 0.9 14.1 6.5 2.8 11.9 12.3 16.8 21.4 13.0 8.2 31.4 9.1 9.8 12.1 6.4 16.4 14.7 5.5 5.1 7.6 11.6 9.6 7.3 6.7 3.5 9.3 5.4 8.8 5.1 12.2 11.8 8.3 14.4 11.0 12.1 22.8 6.2 15.5 13.5 0.0 0.4 1.5 1.6 0.8 1.1 0.3 1.8 1.7 0.7 0.7 0.6 2.3 0.0 1.4 0.3 0.4 4.0 0.8 1.5 2.4 0.5 2.2 1.2 1.3 1.2 1.4 2.6 1.0 0.0 1.1 0.8 0.6 1.4 2.1 0.5 0.0 2.7 0.0 1.8 0.0 3.6 0.0 0.6 48.9 0.4 0.0 23.3 0.3 10.4 0.7 0.4 1.1 0.2 3.1 0.0 2.4 0.6 1.0 60.1 2.6 1.6 0.0 1.8 1.9 1.1 0.1 0.0 0.4 0.3 0.7 0.0 0.3 27.0 12.1 0.6 3.2 1.8 2.1 0.9 PLK5 "PLK5P, SgK384ps" ENSG00000185988 "Polo like kinase 5" Q496M5 19 1524074-1536046 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 50.1" "Group enriched" "Detected in some" 5 "Leydig cells: 33.6;Peritubular cells: 63.6" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in all" 6 "cerebellum: 50.1" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 5.0" HPA035024 Enhanced NA NA "HPA035024: AB_2674418" "unprognostic (4.32e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (7.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-1)" "unprognostic (2.69e-1)" "unprognostic (8.38e-2)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" "unprognostic (3.36e-2)" "unprognostic (9.94e-3)" "unprognostic (2.18e-3)" "unprognostic (3.21e-1)" "unprognostic (7.49e-2)" "unprognostic (3.54e-2)" "unprognostic (4.01e-4)" 0.4 0.7 8.3 0.4 4.8 1.7 0.8 50.1 7.9 5.9 0.4 1.6 0.3 0.5 6.4 6.2 1.6 2.7 0.4 0.3 3.2 1.7 0.3 0.3 0.3 0.4 1.1 1.9 0.8 0.6 0.5 0.5 0.3 2.9 0.9 0.4 8.4 0.6 3.2 0.5 1.0 0.7 2.8 0.8 0.4 0.2 7.4 1.8 0.0 0.4 0.0 0.3 0.2 2.9 1.2 1.2 4.4 0.9 1.0 1.1 0.1 0.2 0.9 0.8 1.2 0.4 0.9 1.0 0.2 0.5 0.5 0.4 0.5 1.0 5.0 0.3 0.5 0.3 1.2 0.8 0.5 0.2 0.5 0.7 1.0 1.3 0.8 0.1 0.2 1.1 1.0 0.3 0.8 0.2 2.0 0.3 0.7 0.8 1.7 0.8 1.0 0.4 1.0 1.4 0.3 0.9 1.0 0.3 0.4 0.6 0.1 0.5 0.7 0.7 0.4 0.3 0.6 1.5 0.7 0.0 0.9 1.0 1.3 0.2 1.5 0.4 0.6 0.4 0.7 0.5 1.6 0.9 2.2 0.8 0.5 0.5 0.7 0.8 0.5 0.2 1.2 1.1 0.6 4.4 1.0 0.6 1.2 1.0 0.1 8.3 4.8 50.1 7.9 3.2 1.7 1.1 1.9 2.9 1.8 0.0 0.0 0.0 0.1 0.1 2.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 33.6 0.0 1.7 0.0 0.0 10.1 0.0 0.0 63.6 0.0 0.6 0.0 0.0 0.0 2.1 0.1 0.1 0.0 0.0 0.1 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669730-153689010 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4;seminal vesicle: 38.5" "Cell type enhanced" "Detected in some" 13 "Bipolar cells: 16.5;Cone photoreceptor cells: 21.6;Extravillous trophoblasts: 44.0;Rod photoreceptor cells: 19.4;Syncytiotrophoblasts: 41.4" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "AN3-CA: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.8 21.4 2.2 35.4 0.6 0.9 3.7 24.9 0.9 21.9 0.9 6.9 3.8 4.2 3.1 14.5 2.9 2.9 3.8 19.5 17.0 1.0 0.5 0.7 0.6 6.1 15.5 0.7 0.5 1.4 0.3 2.4 3.8 12.6 4.2 0.4 0.7 38.5 2.2 1.4 5.2 15.3 2.6 0.7 5.5 4.7 1.7 0.0 0.5 0.0 0.7 10.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.4 27.1 0.0 0.0 2.9 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.3 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.3 0.2 0.1 0.5 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.2 3.2 0.0 0.1 2.2 0.8 0.3 0.3 0.0 0.2 1.1 0.0 0.2 0.2 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 35.4 3.7 23.2 19.5 17.0 6.1 15.5 3.8 1.7 0.0 0.0 0.0 0.4 0.6 16.5 2.8 0.0 0.0 0.0 0.0 21.6 8.3 0.0 0.2 0.2 0.3 2.0 0.0 0.3 44.0 0.2 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.4 2.7 4.8 0.0 0.4 0.1 19.4 0.0 0.4 0.5 0.6 0.5 41.4 0.0 0.0 0.9 POMK "FLJ23356, SgK196" ENSG00000185900 "Protein-O-mannose kinase" Q9H5K3 8 43093506-43123434 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Kinase, Transferase" "Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" 8 "Bipolar cells: 1.4;Club cells: 2.3;Melanocytes: 1.7;monocytes: 1.8;Spermatogonia: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013321 Uncertain Approved Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA013321: AB_2668809" "unprognostic (1.66e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-1)" "unprognostic (4.37e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.56e-2)" "unprognostic (2.42e-1)" "unprognostic (2.50e-1)" "unprognostic (8.10e-2)" "unprognostic (1.23e-3)" "unprognostic (1.03e-1)" "unprognostic (2.32e-1)" "unprognostic (7.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.71e-3)" "unprognostic (2.10e-2)" 4.7 5.5 9.8 5.6 14.3 12.5 5.1 12.3 18.6 6.9 4.8 8.3 2.2 4.5 6.9 4.4 7.1 6.2 4.8 3.8 7.7 7.0 3.4 4.5 5.5 6.0 4.8 11.1 5.8 9.3 6.3 7.4 6.1 10.5 5.6 5.9 6.1 6.8 4.0 6.2 7.1 5.6 6.4 6.7 7.6 6.8 7.1 7.2 7.5 7.4 3.2 7.4 4.6 5.0 2.6 2.6 6.7 2.9 1.0 3.3 1.3 3.5 7.6 5.8 15.2 2.8 3.5 5.5 2.1 3.2 5.5 4.1 5.5 9.2 5.0 4.7 3.8 2.3 5.9 8.3 6.4 5.4 1.9 1.4 14.0 5.6 2.5 2.0 4.7 7.9 3.8 2.7 7.4 5.3 1.7 5.4 7.1 3.3 14.9 3.7 1.6 10.0 2.0 11.9 2.1 1.0 6.8 6.8 2.9 1.5 9.9 5.6 4.2 9.1 3.2 3.0 4.4 9.8 3.3 7.5 8.4 8.5 8.7 4.2 4.9 8.6 9.4 3.6 3.2 10.0 0.8 2.9 1.9 2.3 2.4 3.3 1.8 1.3 1.3 2.6 2.6 1.8 2.3 6.7 1.0 1.5 2.5 1.1 1.3 9.8 14.3 12.3 18.6 7.7 7.0 4.8 11.1 10.5 7.2 0.0 0.3 0.0 0.1 0.3 1.4 0.3 0.0 0.0 2.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.7 1.8 0.0 0.5 0.3 0.0 0.0 0.0 0.8 0.0 0.1 0.4 1.4 0.1 0.5 0.0 0.2 0.1 PRAG1 "DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223" ENSG00000275342 "PEAK1 related, kinase-activating pseudokinase 1" Q86YV5 8 8317736-8386498 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4" "Cell type enhanced" "Detected in some" 11 "Alveolar cells type 1: 8.9;Alveolar cells type 2: 6.2;Cytotrophoblasts: 6.4;Ductal cells: 6.6;Extravillous trophoblasts: 5.5;Hofbauer cells: 14.8;Pancreatic endocrine cells: 5.5" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 27.5;NTERA-2: 17.8;SuSa: 19.0" "Low region specificity" "Detected in all" "HPA011776, HPA012066" Uncertain Uncertain "Nucleoli,Focal adhesion sites" NA NA Nucleoli "Focal adhesion sites" "HPA011776: , HPA012066: AB_1847706" "unprognostic (7.04e-3)" "unprognostic (7.90e-2)" "unprognostic (2.32e-1)" "unprognostic (2.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.92e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-3)" "unprognostic (2.64e-3)" "unprognostic (5.19e-2)" "unprognostic (4.95e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (5.27e-2)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (5.22e-3)" 7.6 0.2 6.4 8.8 4.9 0.1 5.4 30.4 7.0 2.4 5.7 1.8 3.2 9.8 0.8 1.7 2.6 5.0 4.0 1.8 2.1 1.3 0.9 4.3 9.1 0.0 1.4 1.7 1.0 2.2 0.0 5.4 1.2 1.5 3.4 0.0 1.7 5.7 5.6 2.8 9.4 0.9 1.4 5.7 3.9 0.7 1.2 1.8 15.4 4.7 6.2 1.5 0.2 3.1 4.6 2.2 1.6 1.3 3.9 0.4 3.3 27.5 3.1 0.4 0.0 0.2 7.8 7.0 1.5 2.8 1.1 13.6 8.0 5.5 4.8 3.3 7.6 12.0 0.5 8.4 0.6 0.2 0.8 0.0 3.3 7.6 3.0 0.8 8.7 0.7 5.5 0.4 1.2 1.6 5.7 0.8 0.0 0.0 2.1 4.6 0.7 2.6 17.8 10.5 7.1 3.5 3.3 1.3 4.1 9.5 1.5 1.0 2.7 7.7 2.7 19.0 6.0 3.4 7.5 0.2 7.4 0.0 1.7 0.4 0.6 7.5 1.7 1.8 4.1 0.0 0.5 2.2 1.2 0.1 0.9 3.1 1.5 0.4 0.7 2.6 3.9 3.2 0.0 1.3 1.6 4.6 0.2 0.4 8.9 6.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 6.4 0.0 6.6 0.0 0.0 0.0 0.0 2.7 5.5 0.0 0.0 2.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.8 0.0 0.0 5.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759379-40798374 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 9 "Early spermatids: 230.0;Late spermatids: 337.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "CAB005050: AB_562037, HPA035409: AB_2674613, HPA064946: AB_2685390" "unprognostic (2.07e-1)" "unprognostic (1.41e-2)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (3.97e-1)" "unprognostic (1.05e-1)" "unprognostic (3.51e-2)" "unprognostic (7.53e-2)" "unprognostic (1.66e-2)" "unprognostic (2.88e-1)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (2.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-2)" 40.6 15.7 9.4 15.9 16.1 29.0 26.2 14.3 17.7 30.2 24.0 19.9 18.9 21.7 23.5 20.9 22.5 20.4 21.3 15.0 10.5 11.7 35.9 40.7 24.8 16.7 12.2 8.5 28.8 20.6 25.3 20.0 16.8 35.7 26.1 22.3 20.0 23.2 17.9 18.5 16.6 32.6 20.7 14.1 25.1 22.1 29.3 11.4 21.4 28.0 20.5 22.9 32.5 17.9 8.4 6.5 15.9 8.9 10.8 12.6 6.5 11.4 11.9 9.6 12.7 23.7 24.8 9.1 19.6 20.0 14.7 13.2 11.2 14.9 6.7 9.1 20.0 19.2 9.3 8.8 17.8 27.7 19.8 8.0 13.4 27.6 8.9 19.6 12.7 14.2 22.8 8.7 19.6 20.3 16.3 21.6 8.7 6.3 19.6 21.9 5.5 11.8 10.0 4.2 11.7 14.4 9.9 20.5 9.9 22.5 19.5 8.3 8.4 34.3 22.8 11.6 5.4 12.0 10.6 23.1 26.5 14.3 15.2 15.9 7.8 6.1 8.1 16.6 27.7 14.1 14.1 6.6 12.7 10.0 8.1 12.6 8.4 9.4 9.4 6.5 7.7 11.5 10.0 15.9 10.8 8.9 2.0 11.3 6.5 9.4 16.1 14.3 17.7 10.5 11.7 12.2 8.5 35.7 11.4 38.7 27.4 25.1 20.8 21.4 19.2 15.3 43.3 22.7 28.4 45.4 33.4 10.9 6.6 24.4 230.0 32.8 33.8 0.0 39.5 11.7 23.6 34.6 17.4 73.6 17.7 14.3 20.3 36.2 21.5 337.0 28.1 24.1 33.7 36.1 27.4 15.4 29.5 31.7 24.4 26.4 25.7 0.0 33.0 20.4 16.8 28.5 15.6 28.8 30.2 28.0 PRKAA2 "AMPK, AMPKa2, PRKAA" ENSG00000162409 "Protein kinase AMP-activated catalytic subunit alpha 2" P54646 1 56645322-56715335 "Enzymes, Predicted membrane proteins, Transporters" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 40.2" "Cell type enhanced" "Detected in many" 16 "Cardiomyocytes: 309.5;Rod photoreceptor cells: 106.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044540 Approved Supported "Nuclear speckles,Golgi apparatus" NA NA "Nuclear speckles" "Golgi apparatus" "HPA044540: AB_2678977" "unprognostic (4.17e-3)" "unprognostic (1.62e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (4.80e-4)" "unprognostic (9.35e-2)" "unprognostic (1.92e-3)" "prognostic unfavorable (5.30e-4)" "unprognostic (7.30e-2)" "unprognostic (3.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.97e-1)" "unprognostic (8.64e-2)" "prognostic favorable (4.95e-5)" "unprognostic (1.30e-2)" "unprognostic (4.52e-2)" "unprognostic (1.57e-2)" "unprognostic (1.85e-1)" 2.4 2.1 3.7 1.2 6.3 0.7 4.1 7.2 8.1 2.2 5.5 1.2 2.4 1.2 3.0 3.2 6.3 3.5 2.6 39.1 4.2 2.9 14.5 1.4 2.0 0.8 2.4 6.2 2.5 2.6 10.4 2.6 1.2 5.0 4.6 2.2 6.0 4.5 3.5 40.2 1.4 2.1 7.2 1.9 1.9 3.2 1.7 0.8 0.0 4.0 12.3 0.8 4.4 2.1 0.2 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.7 2.0 0.0 0.7 0.5 2.3 1.8 1.4 2.4 4.2 3.7 4.7 0.0 0.6 0.6 7.4 0.0 7.7 0.0 7.1 0.0 8.5 0.0 6.9 5.2 0.0 0.0 0.1 0.6 0.0 3.5 0.3 5.7 0.8 1.9 0.0 0.0 1.0 0.1 0.0 0.0 5.5 0.0 5.4 0.0 0.0 0.0 13.9 1.2 2.0 5.4 5.7 0.1 0.0 6.2 3.2 0.0 0.0 1.5 2.3 2.7 6.2 0.0 0.0 0.0 4.5 0.0 1.1 0.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 3.7 6.3 7.2 8.1 4.2 2.9 2.4 6.2 5.0 0.8 8.9 3.7 0.0 5.9 0.8 39.3 309.5 22.9 10.7 15.9 47.1 47.1 0.8 46.4 9.1 2.3 11.7 1.0 0.0 4.1 0.3 3.5 15.6 2.3 6.4 0.1 25.4 13.8 3.7 0.0 1.9 6.4 0.9 5.0 0.0 7.7 16.8 6.7 0.0 27.6 74.2 106.6 6.5 21.2 7.2 2.8 0.4 0.3 0.0 5.2 11.2 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cardiomyocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" NA NA 1300000 Cytosol "Cytokinetic bridge" "CAB010361: AB_2268772, HPA071185: AB_2686356" "unprognostic (1.08e-1)" "prognostic favorable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favorable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 25.6 43.4 19.6 17.8 22.7 9.1 34.1 29.1 39.6 20.6 17.5 16.0 16.2 13.4 19.8 15.6 20.9 18.8 16.4 91.6 20.7 29.4 14.7 34.5 16.5 28.2 21.6 27.5 47.0 15.6 20.8 24.6 15.4 26.9 16.6 16.2 18.4 15.5 24.9 92.4 13.4 14.4 29.0 16.2 28.1 13.9 24.4 11.1 15.2 15.7 26.2 14.8 21.1 17.3 1.7 2.4 8.6 5.3 0.7 1.7 1.2 26.2 15.3 34.7 41.3 30.7 32.7 6.3 28.0 25.9 39.8 36.5 18.6 9.4 11.4 22.7 44.3 19.4 17.2 24.4 26.5 37.8 20.7 12.3 20.9 28.9 18.0 26.3 12.9 22.2 31.1 12.8 31.6 11.0 24.6 33.5 18.7 19.6 29.8 40.6 38.9 29.0 9.7 12.4 26.6 34.1 26.2 32.0 26.3 19.4 16.7 27.4 17.5 25.3 15.5 11.5 17.5 22.1 12.5 25.9 47.0 13.1 62.9 26.1 20.6 21.1 16.8 31.5 19.6 17.6 0.3 3.4 0.4 1.7 5.3 0.8 1.7 0.9 1.1 2.4 1.3 1.2 1.7 8.6 0.7 4.6 1.6 0.8 1.2 19.6 22.7 29.1 39.6 20.7 29.4 21.6 27.5 26.9 11.1 6.0 4.3 11.5 6.1 7.8 40.4 110.4 28.1 4.0 2.3 14.0 25.5 5.8 6.6 10.7 25.7 21.6 16.0 0.0 16.2 4.8 14.3 7.3 0.0 30.1 29.0 3.2 16.8 31.9 44.8 12.8 45.5 32.4 13.5 7.2 14.3 24.1 13.5 7.0 48.8 9.6 23.0 19.4 17.3 25.7 6.4 9.8 6.8 7.2 11.4 6.4 PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 85.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010363, HPA029754, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" NA NA 1500000 Cytosol "Cytokinetic bridge" "CAB010363: AB_2170182, HPA029754: AB_10601491, HPA071185: AB_2686356" "unprognostic (9.38e-2)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.49e-4)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "prognostic favorable (1.89e-6)" "unprognostic (1.22e-1)" "unprognostic (3.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.48e-1)" 7.0 21.5 40.0 10.5 57.0 6.2 8.0 54.7 85.5 9.4 23.6 16.9 3.9 4.8 8.7 17.6 8.1 5.2 11.5 10.1 43.1 52.1 10.6 9.0 6.9 16.2 38.3 33.5 8.3 11.9 12.2 18.3 5.1 35.5 13.8 22.6 4.9 32.9 12.7 3.2 2.6 6.3 12.6 47.7 14.6 14.2 3.6 25.9 25.5 11.1 1.8 15.3 13.5 4.6 13.5 7.1 17.1 5.4 25.9 27.6 22.0 3.1 6.3 10.1 12.1 11.7 10.3 4.7 15.6 11.9 8.0 7.5 0.1 2.8 16.6 10.8 12.2 14.6 2.2 4.7 5.1 8.5 16.1 2.6 36.5 8.6 1.2 11.5 14.4 0.8 6.1 2.3 7.7 4.3 11.6 36.6 6.2 1.1 9.6 12.9 0.6 18.7 7.6 9.9 0.0 4.4 14.5 15.7 10.0 19.4 11.2 3.3 12.9 8.6 3.3 9.5 7.9 3.0 3.0 32.4 11.1 8.6 11.2 11.8 7.1 8.5 16.7 5.3 15.4 13.8 17.1 2.7 5.8 23.3 3.6 18.7 13.5 17.3 20.6 7.1 10.2 26.4 27.6 1.5 25.9 5.4 4.1 15.9 22.0 40.0 57.0 54.7 58.2 43.1 52.1 38.3 33.5 35.5 25.9 0.0 1.0 20.3 6.7 4.5 44.0 38.9 15.3 4.0 5.7 14.0 33.4 1.4 28.2 6.9 2.4 8.4 61.7 0.0 10.3 1.0 11.0 15.2 57.7 14.8 23.2 44.5 20.8 26.4 52.7 2.6 13.8 32.7 15.1 1.0 61.1 36.9 13.3 28.8 20.5 15.6 30.0 12.9 13.7 5.9 6.9 2.5 0.6 69.2 52.4 6.5 PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012529-69014113 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 27.4" "Group enriched" "Detected in some" 8 "Early spermatids: 55.1;Late spermatids: 73.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CACO-2: 1.3" "CAB004530, HPA071185" Supported Uncertain "Cytokinetic bridge,Cytosol" NA NA Cytosol "Cytokinetic bridge" "CAB004530: AB_628137, HPA071185: AB_2686356" "unprognostic (2.74e-1)" "unprognostic (3.61e-2)" "unprognostic (7.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 1.5 0.0 0.0 0.0 0.0 0.0 PRKCA PKCA ENSG00000154229 "Protein kinase C alpha" P17252 17 66302636-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Rod photoreceptor cells: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 17 "dendritic cells: 1.4;monocytes: 2.7;T-cells: 4.0" "Cell line enhanced" "Detected in many" "U-87 MG: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" NA NA 1900000 Cytosol "Plasma membrane" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" 4.0 19.6 26.5 9.0 22.8 2.5 3.0 10.8 33.9 7.0 13.8 19.0 3.5 14.6 14.8 6.7 4.7 6.1 10.8 5.8 31.6 15.6 16.7 6.5 6.0 8.4 18.7 15.6 20.4 5.5 1.7 6.0 6.5 17.6 17.2 11.2 7.0 3.1 22.3 6.6 3.8 12.7 13.7 15.0 7.9 7.9 3.7 14.4 0.4 4.5 1.3 5.9 9.5 9.5 0.0 1.4 0.1 2.7 0.1 4.0 1.0 2.3 12.5 2.6 2.6 6.3 16.1 0.3 13.4 8.8 9.7 8.3 1.4 1.5 3.1 3.6 21.7 16.3 0.3 1.3 1.6 21.2 5.2 3.0 0.0 7.4 6.5 8.6 3.9 21.1 7.0 0.6 12.1 10.4 14.2 8.3 15.1 8.1 0.0 15.0 0.7 7.8 2.4 1.0 6.1 6.7 1.4 19.1 0.0 3.4 2.1 1.5 8.6 4.4 2.6 0.1 2.8 0.3 5.5 24.8 16.9 9.8 10.5 8.4 0.0 0.0 0.3 53.7 0.0 8.3 0.1 0.6 0.0 0.5 0.8 1.5 0.0 2.5 1.2 1.1 0.0 4.0 2.3 0.0 0.1 2.7 1.4 0.5 1.0 26.5 22.8 10.8 28.2 31.6 15.6 18.7 15.6 17.6 14.4 0.0 9.6 3.9 15.4 9.4 33.9 7.9 40.8 5.3 4.5 38.4 2.0 3.3 6.6 11.3 2.5 3.0 24.2 0.0 5.9 2.8 11.0 12.4 20.7 11.9 19.7 9.5 8.1 36.8 8.2 1.3 49.5 7.7 10.1 1.8 32.8 43.1 7.2 20.1 45.6 16.8 77.1 25.8 17.0 1.1 1.7 9.2 12.7 24.1 21.3 12.3 PRKCB "PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835946-24220611 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.2;lymphoid tissue: 31.2" "Cell type enhanced" "Detected in many" 11 "B-cells: 149.8;Bipolar cells: 172.0;Horizontal cells: 74.7;Kupffer cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 41.7;HMC-1: 41.8;K-562: 59.4;THP-1: 18.8;U-937: 16.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol NA NA 3400000 Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: AB_2680357, HPA054203: AB_2682416" "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.0 1.9 13.9 20.8 55.6 20.4 1.8 14.1 57.2 4.1 4.7 4.4 0.6 4.9 3.5 1.2 3.2 2.6 3.9 1.5 23.4 7.8 1.8 3.7 5.4 31.0 11.0 20.4 1.2 1.4 0.9 1.4 2.5 8.3 6.2 4.4 3.5 1.9 8.4 1.2 4.6 9.1 5.8 7.3 31.2 3.8 6.4 6.4 24.1 3.9 0.0 27.7 7.6 1.7 23.6 18.5 21.8 14.6 20.1 19.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 41.7 2.0 0.0 0.0 6.0 41.8 0.0 0.2 0.0 0.0 0.0 0.0 7.2 59.4 0.1 0.0 0.0 13.1 13.2 0.4 0.0 0.0 12.5 0.1 2.4 0.1 3.6 7.3 0.0 0.0 0.0 0.6 0.2 0.0 18.8 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 16.8 0.0 17.5 7.6 14.4 14.5 10.7 6.7 23.6 9.5 17.2 6.2 22.1 7.8 19.0 21.8 20.1 14.6 18.5 6.7 7.5 13.9 55.6 14.1 57.2 23.4 7.8 11.0 20.4 8.3 6.4 3.0 8.2 149.8 3.5 5.4 172.0 1.7 5.1 2.7 1.2 1.8 2.0 0.1 0.0 0.0 16.3 1.4 1.7 0.0 0.2 0.2 1.3 0.7 69.4 1.6 41.0 74.7 0.0 16.5 192.8 10.0 0.0 22.7 3.3 6.4 0.7 9.9 0.0 9.5 0.4 0.1 7.3 0.0 2.2 3.6 3.7 12.5 0.7 57.5 1.2 4.3 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 17.7;classical monocyte: 22.9;eosinophil: 17.0;intermediate monocyte: 22.2;myeloid DC: 17.6;neutrophil: 20.7;non-classical monocyte: 15.3;plasmacytoid DC: 8.5" "Group enriched" "Detected in all" 7 "dendritic cells: 17.6;granulocytes: 20.7;monocytes: 22.9" "Cell line enhanced" "Detected in all" "SK-BR-3: 64.7;THP-1: 46.1" "Group enriched" "Detected in many" 5 "basal ganglia: 124.2;thalamus: 366.1" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 300000 Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 27.8 33.4 9.4 29.7 11.5 30.3 17.6 5.7 10.7 10.3 27.8 10.1 43.7 21.4 5.5 21.3 18.3 16.1 33.7 11.9 8.3 3.7 16.5 4.5 29.2 24.5 10.2 5.6 8.1 13.4 6.1 5.1 7.5 7.1 17.9 16.1 10.3 14.1 40.7 3.9 17.1 42.9 17.4 10.2 32.1 24.8 9.6 8.0 10.5 26.9 13.4 26.3 22.9 12.7 3.1 17.6 20.7 22.9 2.4 1.5 6.4 7.9 3.0 1.2 2.1 9.2 5.3 11.4 4.8 6.1 5.9 5.8 7.4 7.8 20.4 2.1 10.4 10.3 3.6 8.1 11.8 4.9 17.8 6.1 11.3 4.2 7.9 5.9 14.9 25.7 4.1 8.6 6.1 5.6 5.3 5.1 2.2 2.2 2.9 8.5 19.5 1.6 25.5 3.2 11.9 5.6 1.7 3.1 4.9 6.4 17.0 2.0 1.4 3.6 64.7 9.9 6.3 5.4 46.1 7.4 2.9 3.6 3.8 4.5 4.5 6.9 10.5 6.8 25.8 5.5 17.7 22.9 17.0 1.5 22.2 1.0 3.1 1.1 1.2 17.6 2.9 0.8 0.7 20.7 2.4 15.3 8.5 1.1 6.4 9.4 11.5 5.7 10.7 8.3 3.7 10.2 5.6 7.1 8.0 3.0 19.7 17.6 21.2 26.0 0.0 4.5 12.7 16.0 17.0 14.0 0.0 2.5 3.3 7.6 26.7 1.8 56.8 0.0 9.6 13.5 8.7 14.8 5.7 1.7 38.4 1.6 25.5 3.7 43.0 59.4 8.3 35.2 10.1 21.6 29.0 1.8 10.3 49.1 6.3 10.9 0.0 6.5 9.4 5.2 1.9 24.3 7.3 7.5 20.6 28.8 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 36.5" "Group enriched" "Detected in many" 5 "Early spermatids: 209.3;Late spermatids: 297.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "naive B-cell: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 19.4;TIME: 19.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 5.5 7.4 15.3 7.2 14.2 9.3 8.1 28.8 36.5 6.6 5.5 3.8 5.9 3.6 5.6 4.6 4.7 7.6 4.7 7.7 22.5 10.0 12.8 15.5 17.5 6.9 6.0 15.0 4.1 4.2 16.3 6.0 10.4 9.1 3.6 4.7 3.7 3.6 8.6 7.2 3.0 3.7 6.2 4.4 4.9 4.4 7.2 3.7 1.5 6.5 1.2 5.4 5.0 6.5 5.5 2.2 1.7 1.4 0.9 1.3 0.6 5.4 2.0 2.9 2.9 4.4 5.2 2.3 3.8 7.0 3.2 3.5 0.5 5.4 8.2 3.6 4.0 4.6 1.3 1.8 2.0 4.6 4.9 3.5 0.0 1.4 1.1 5.0 0.6 2.9 4.6 2.3 4.8 3.5 2.7 11.8 1.8 1.1 2.0 3.7 2.8 2.6 0.3 1.0 3.0 1.0 19.4 13.8 8.8 2.9 3.7 2.0 4.4 1.7 5.8 12.5 1.1 4.7 1.9 19.5 6.3 6.6 4.6 3.8 0.0 0.0 6.9 5.2 4.6 6.3 0.0 1.2 1.7 1.0 0.4 1.1 3.6 0.7 0.7 2.2 5.5 1.3 0.4 0.4 0.9 1.4 0.9 0.0 0.6 15.3 14.2 28.8 33.2 22.5 10.0 6.0 15.0 9.1 3.7 6.0 8.6 20.1 6.3 4.4 47.5 9.3 12.7 22.7 27.3 10.4 13.7 0.3 3.3 3.0 209.3 9.9 4.5 0.0 3.3 6.9 8.0 5.7 6.9 7.3 2.6 11.1 7.5 12.3 17.0 297.3 4.9 11.1 13.5 7.2 5.3 7.0 3.0 3.5 5.6 21.3 6.7 12.9 6.6 2.7 2.2 4.3 2.4 4.3 6.2 7.1 PRKCG "MGC57564, PKCC, PKCG, SCA14" ENSG00000126583 "Protein kinase C gamma" P05129 19 53879190-53907652 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 49.9" "Cell type enhanced" "Detected in some" 15 "Early spermatids: 3.7;Horizontal cells: 4.8;Spermatocytes: 2.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.8;OE19: 8.5;SH-SY5Y: 3.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054560 Enhanced NA NA "HPA054560: AB_2682523" "unprognostic (7.14e-2)" "unprognostic (5.42e-2)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.96e-2)" "unprognostic (4.46e-2)" "unprognostic (2.09e-1)" "unprognostic (2.64e-2)" "unprognostic (7.48e-3)" "unprognostic (2.68e-1)" "unprognostic (2.22e-7)" "unprognostic (2.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" 1.0 0.9 28.0 1.1 49.9 2.2 0.9 12.1 39.2 0.9 1.3 1.6 0.0 1.5 1.0 0.9 1.0 1.4 1.0 0.9 49.7 4.4 0.9 0.9 1.0 0.9 2.9 20.8 0.9 3.5 2.1 0.2 0.9 0.7 0.9 1.2 0.0 0.9 1.0 1.0 0.9 1.3 1.1 1.4 0.9 1.8 4.4 2.1 1.3 0.9 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 4.8 1.0 0.0 0.0 0.2 0.1 0.6 0.3 0.0 0.0 1.2 1.3 0.2 1.4 0.0 0.5 0.4 2.3 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.5 0.0 0.9 0.0 1.2 0.0 0.1 0.0 0.5 0.4 0.1 0.8 8.5 0.4 0.8 0.5 0.0 0.9 0.0 0.0 3.3 1.3 0.1 0.0 1.7 1.6 0.0 0.8 0.0 1.6 0.0 0.0 1.4 0.3 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.0 49.9 12.1 28.5 49.7 4.4 2.9 20.8 0.7 2.1 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 4.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.0 0.0 0.0 0.0 0.2 0.1 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Endothelial cells: 56.0;Erythroid cells: 70.0;Ito cells: 55.9;T-cells: 137.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "gdT-cell: 30.0;MAIT T-cell: 23.9;memory CD4 T-cell: 23.0;memory CD8 T-cell: 35.3;naive CD4 T-cell: 28.5;naive CD8 T-cell: 27.6;NK-cell: 27.3;T-reg: 18.6" "Group enriched" "Detected in many" 14 "NK-cells: 27.3;T-cells: 35.3" "Cell line enhanced" "Detected in many" "BEWO: 30.4;HUVEC TERT2: 39.9;MOLT-4: 26.5;RT4: 16.8;TIME: 26.1" "Group enriched" "Detected in many" 6 "basal ganglia: 25.0;thalamus: 19.5" "Low region specificity" "Detected in many" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 17.5 5.4 5.0 21.6 22.0 11.2 14.7 2.8 6.1 13.6 10.3 6.2 6.9 5.1 19.1 7.0 20.1 8.6 12.7 10.1 6.8 4.4 8.1 5.5 24.1 27.6 5.9 2.5 7.1 5.9 8.8 15.5 22.7 7.2 9.8 5.0 9.1 24.7 10.8 9.1 15.9 16.0 10.5 5.7 25.9 6.0 4.3 6.4 54.6 15.1 10.6 34.6 13.2 14.4 0.4 2.2 1.5 0.7 27.3 35.3 17.9 6.4 2.2 0.3 1.7 1.0 0.2 30.4 0.1 0.5 0.3 0.3 0.7 3.8 0.1 4.6 0.0 0.6 4.4 0.2 4.9 0.5 0.8 2.9 0.0 0.7 0.2 0.4 0.0 0.9 0.8 5.1 0.2 3.5 0.4 39.9 12.9 0.0 0.1 2.3 11.7 26.5 0.2 0.5 4.6 3.1 2.2 1.1 0.0 0.0 16.8 1.1 1.9 0.7 5.9 3.6 5.6 5.8 0.5 26.1 0.7 5.2 0.8 0.3 0.5 0.1 0.2 1.1 0.4 1.3 0.1 0.7 0.5 30.0 0.4 23.9 0.4 23.0 35.3 2.2 0.3 28.5 27.6 1.5 27.3 0.2 0.7 18.6 17.9 5.0 22.0 2.8 6.1 6.8 4.4 5.9 2.5 7.2 6.4 6.0 10.7 4.6 15.8 16.7 0.2 3.9 10.2 10.7 18.2 0.0 0.0 23.4 3.3 4.6 25.5 56.0 1.7 70.0 5.9 16.9 3.7 13.1 1.1 1.0 5.6 0.0 11.3 55.9 11.1 3.6 1.7 9.0 15.1 5.4 2.6 9.3 4.4 2.9 6.3 0.8 0.3 0.0 4.1 0.0 2.1 23.3 40.4 137.1 0.7 24.4 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222365-170305981 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: AB_2676124" "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favorable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 10.3 7.5 11.4 5.9 15.5 2.1 9.5 14.8 16.6 12.5 11.1 7.0 6.0 10.4 13.1 8.4 20.6 15.1 10.5 10.1 9.5 7.7 13.0 6.7 14.8 3.9 5.6 9.4 15.2 7.7 12.4 14.7 9.8 11.0 16.3 12.2 7.3 25.8 12.6 12.7 11.0 11.6 12.5 6.8 6.1 30.2 15.0 5.3 12.6 23.1 8.4 9.9 16.3 13.0 1.9 1.8 1.0 1.3 5.8 4.8 1.4 34.3 8.7 8.8 9.4 7.8 10.9 14.2 8.8 13.0 11.7 12.7 12.7 16.8 10.5 29.1 12.3 16.1 16.1 16.5 17.3 20.1 7.6 10.2 9.7 11.0 7.0 12.4 8.7 4.4 9.8 12.1 10.0 15.7 19.0 9.1 5.8 10.7 8.7 11.7 11.8 12.6 3.4 18.4 36.7 9.7 9.2 13.5 17.3 18.4 10.5 14.0 11.4 19.0 25.0 8.6 13.6 27.5 6.0 9.6 12.2 9.4 11.4 14.5 15.0 14.4 15.0 8.8 6.9 4.7 0.1 1.3 1.0 2.6 1.2 4.0 1.8 3.6 4.8 1.8 1.9 3.9 2.2 0.7 5.8 1.1 1.8 2.3 1.4 11.4 15.5 14.8 16.6 9.5 7.7 5.6 9.4 11.0 5.3 68.5 56.0 2.2 46.0 50.7 15.9 14.9 25.5 22.7 46.6 47.1 13.7 23.8 21.6 13.9 5.5 18.0 21.2 0.0 19.5 22.1 25.6 78.7 8.1 17.8 8.9 14.3 28.2 16.5 20.8 3.6 21.6 10.0 16.9 6.4 28.1 8.1 36.5 17.5 26.9 15.1 9.3 19.4 11.4 12.9 15.1 55.7 17.3 5.7 27.7 69.1 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood: 19.7;lymphoid tissue: 32.1;skeletal muscle: 63.4" "Cell type enhanced" "Detected in many" 19 "Alveolar cells type 2: 6.5;Distal tubular cells: 6.6;T-cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "gdT-cell: 12.7;MAIT T-cell: 9.8;memory CD4 T-cell: 13.5;memory CD8 T-cell: 13.2;naive CD4 T-cell: 10.7;naive CD8 T-cell: 10.0;NK-cell: 6.5;T-reg: 19.7" "Group enriched" "Detected in many" 11 "NK-cells: 6.5;T-cells: 19.7" "Cell line enhanced" "Detected in some" "HEL: 29.8;JURKAT: 21.2;MOLT-4: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA 200000 "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" 0.9 0.7 3.6 9.4 4.3 3.1 0.8 0.9 5.2 1.3 1.1 7.4 0.1 1.2 1.8 5.4 1.6 2.6 1.3 0.5 4.4 4.0 4.6 0.9 3.3 6.6 4.0 2.2 1.1 7.7 0.3 1.0 0.4 2.7 1.4 1.3 5.4 2.8 1.0 63.4 0.6 2.5 0.8 3.6 3.4 1.4 0.9 4.5 32.1 9.1 7.5 6.8 1.9 0.8 0.0 0.1 1.1 0.2 6.5 19.7 5.2 0.0 2.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.2 1.8 0.2 0.0 0.0 0.0 0.0 1.8 3.1 0.0 0.0 2.0 29.8 0.0 0.2 0.3 1.4 0.3 0.1 1.9 0.1 0.1 0.0 0.2 21.2 6.5 0.0 0.0 0.0 22.3 4.2 3.1 0.2 0.0 4.3 0.7 0.0 6.3 1.5 0.2 1.1 0.0 0.0 0.0 1.9 0.0 3.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 1.1 0.1 0.1 12.7 0.2 9.8 0.0 13.5 13.2 0.1 0.0 10.7 10.0 0.8 6.5 0.0 0.0 19.7 5.2 3.6 4.3 0.9 5.2 4.4 4.0 4.0 2.2 2.7 4.5 3.0 6.5 0.0 0.1 0.0 1.6 0.3 0.0 1.4 1.2 1.8 0.0 0.0 6.6 0.2 1.8 0.0 0.0 0.0 0.7 0.1 0.3 0.0 1.1 0.0 0.4 0.0 1.7 1.3 1.5 4.5 0.0 0.5 0.0 0.0 0.3 1.5 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.9 2.0 0.0 0.0 25.4 0.3 0.1 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050470-2185395 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.6;placenta: 93.0" "Group enriched" "Detected in many" 4 "Late spermatids: 539.8;Syncytiotrophoblasts: 926.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "eosinophil: 15.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 15.0" "Cell line enhanced" "Detected in many" "BEWO: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.2 7.8 15.9 3.0 31.8 1.4 3.9 39.8 43.6 3.2 8.6 17.1 2.3 20.0 1.7 5.5 10.1 6.5 3.1 6.4 15.5 6.4 11.3 6.8 22.3 5.0 12.2 23.6 1.9 8.5 9.8 12.0 93.0 27.3 5.8 7.5 2.6 7.0 3.0 0.4 8.8 18.4 1.2 8.4 6.9 6.1 17.5 13.5 0.6 14.1 0.9 5.0 4.0 4.6 0.4 0.3 15.0 0.3 0.8 2.6 0.3 7.3 4.7 1.7 8.7 0.0 0.0 23.0 0.5 0.2 5.5 0.3 11.9 16.0 0.0 14.6 1.8 4.8 12.9 9.9 12.3 3.9 0.5 11.0 0.0 7.6 15.8 1.6 0.0 5.7 0.3 7.4 0.0 4.2 0.0 0.0 1.9 3.2 0.1 0.1 9.0 0.4 0.0 3.3 20.2 11.4 0.0 0.0 2.5 9.4 7.8 12.0 9.7 6.0 13.4 2.5 14.9 9.4 2.0 0.0 0.0 6.9 0.0 0.0 3.5 0.6 0.1 0.6 0.1 8.3 0.3 0.0 15.0 0.6 0.3 2.6 0.3 1.0 0.6 0.0 0.4 0.8 0.4 1.2 0.8 0.0 0.3 0.8 0.3 15.9 31.8 39.8 43.6 15.5 6.4 12.2 23.6 27.3 13.5 113.2 71.1 0.8 10.2 11.6 22.8 1.2 2.5 21.4 26.1 7.0 3.9 84.1 6.6 10.9 181.6 6.0 56.7 0.0 9.3 48.8 3.1 16.4 8.1 12.5 12.7 58.8 9.8 6.7 1.0 539.8 8.9 3.3 6.8 5.4 22.1 15.6 12.2 31.6 8.1 19.0 21.6 0.0 2.2 15.8 26.8 11.7 926.6 7.7 25.3 11.9 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Distal tubular cells: 24.9;Early spermatids: 31.1;Erythroid cells: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 18.2;fHDF/TERT166: 19.3;HSkMC: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" 7.4 10.6 8.0 5.3 9.7 0.7 19.0 4.9 8.9 5.1 8.7 5.1 24.1 3.1 8.3 9.0 3.5 6.8 9.0 6.3 9.8 5.9 15.1 2.3 14.9 1.6 5.6 6.6 15.7 7.3 35.7 9.2 4.5 10.8 20.1 3.5 4.9 3.5 24.4 3.1 2.7 3.5 19.7 16.4 2.4 4.8 16.1 8.6 0.5 8.2 2.9 1.8 14.1 12.2 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.6 4.1 18.2 17.0 0.1 12.3 9.5 12.6 6.8 0.0 0.5 0.0 1.2 19.3 4.3 0.1 6.0 1.4 6.9 0.0 4.2 0.0 0.1 0.4 9.2 0.0 0.1 18.0 0.6 0.9 1.5 6.5 2.5 0.0 1.2 0.4 11.8 1.4 0.0 0.0 2.5 0.0 6.4 0.0 7.1 3.2 13.5 5.7 3.6 7.2 2.1 0.0 4.7 4.9 0.0 0.1 6.4 12.0 4.9 1.0 3.5 0.0 0.0 0.0 3.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 8.0 9.7 4.9 8.9 9.8 5.9 5.6 6.6 10.8 8.6 0.0 6.1 0.0 3.8 0.5 1.2 1.4 7.6 0.0 0.0 12.2 5.9 0.0 24.9 1.5 31.1 4.5 0.0 23.3 3.6 0.1 3.8 16.3 0.0 1.5 0.2 1.6 2.9 12.3 2.6 12.4 6.9 0.3 6.8 0.0 0.2 16.1 3.2 0.0 12.0 3.7 2.8 0.0 4.7 3.4 4.9 0.6 0.2 0.0 0.0 0.9 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 58.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" 17.1 7.6 7.0 25.8 6.5 18.1 18.0 2.5 6.8 16.8 13.7 5.8 18.7 13.7 14.8 16.5 23.4 15.6 17.4 7.4 6.3 3.1 13.2 9.1 21.3 24.8 7.5 2.7 17.0 12.5 10.3 17.2 20.1 6.6 14.8 7.7 11.9 15.6 21.5 7.5 26.8 19.8 11.7 6.8 34.8 15.2 6.6 7.2 41.5 18.7 10.5 33.0 17.4 37.5 6.6 0.4 7.3 1.0 2.9 6.1 1.9 8.8 13.7 5.4 6.6 4.5 3.6 7.0 4.6 7.3 9.6 10.6 7.6 8.6 10.3 8.1 6.1 5.2 13.2 4.8 12.3 3.0 8.7 7.1 10.8 4.2 3.9 6.0 7.9 16.1 4.4 6.0 5.5 4.7 7.2 16.9 9.7 6.9 14.9 3.9 9.3 15.1 25.6 4.6 12.8 7.0 9.9 2.6 16.7 5.9 13.2 3.5 11.0 8.6 7.2 1.8 5.9 5.7 3.1 8.0 4.1 8.2 3.4 3.7 14.6 58.2 5.1 4.3 6.5 4.3 0.9 1.0 3.4 5.6 0.9 4.9 6.1 5.7 6.1 0.4 6.6 5.1 4.9 7.3 2.9 0.7 0.0 4.0 1.9 7.0 6.5 2.5 6.8 6.3 3.1 7.5 2.7 6.6 7.2 8.9 13.5 45.5 26.8 19.6 5.8 11.5 17.8 4.0 10.3 8.7 0.0 11.1 6.6 16.0 0.9 29.2 30.9 23.3 24.3 11.4 10.0 21.5 13.9 7.3 7.7 1.6 20.7 36.2 12.7 2.4 10.9 7.2 11.8 5.4 17.7 6.1 22.1 24.6 6.3 7.1 4.5 12.9 5.9 2.8 15.8 23.3 24.8 23.0 11.2 24.6 PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324808 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Rod photoreceptor cells: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029529 Uncertain Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA029529: AB_10602082" "unprognostic (1.39e-1)" "unprognostic (7.34e-2)" "prognostic favorable (4.84e-4)" "unprognostic (1.23e-2)" "unprognostic (5.61e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.81e-1)" "unprognostic (7.62e-3)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" 16.1 22.1 9.5 20.7 10.7 5.3 35.1 4.8 9.2 17.2 18.0 7.2 7.2 6.0 19.2 16.0 9.8 11.3 10.0 11.6 12.7 6.1 9.9 8.4 20.4 22.3 11.4 3.7 15.0 7.6 12.9 20.7 11.1 10.3 14.4 8.3 27.8 11.1 13.3 19.1 11.5 12.1 16.5 15.4 22.0 10.5 16.8 10.8 16.2 11.8 9.3 21.2 12.4 17.7 16.4 8.2 5.7 8.3 6.3 11.5 3.4 12.8 5.4 14.5 11.9 11.1 18.6 10.6 8.3 15.5 9.4 9.6 8.7 4.5 18.8 7.0 12.4 14.1 5.1 9.8 10.2 12.7 24.3 14.4 12.4 8.4 5.8 4.5 8.8 7.6 8.8 5.2 14.9 9.8 8.7 16.7 6.3 10.4 23.2 10.9 2.1 3.8 6.9 15.3 0.1 5.3 13.0 22.9 16.1 6.2 14.4 10.9 28.3 8.0 4.6 48.8 7.8 4.9 8.1 16.1 27.0 14.0 10.7 9.3 26.5 49.1 22.0 9.4 3.7 16.2 5.7 8.3 5.5 10.5 6.6 9.1 12.4 8.8 8.4 7.8 16.4 10.4 11.5 1.5 6.3 3.3 8.2 4.1 3.4 9.5 10.7 4.8 9.2 12.7 6.1 11.4 3.7 10.3 10.8 38.7 16.2 38.3 20.7 33.7 29.6 7.1 15.3 5.3 13.6 17.4 64.8 9.1 3.3 10.9 42.2 44.7 5.4 0.0 9.0 28.2 34.8 27.0 77.1 11.3 11.1 41.3 18.1 38.1 28.4 78.9 31.1 24.5 47.2 12.6 6.1 16.0 12.3 3.5 29.0 7.1 110.0 25.8 26.9 56.0 44.5 20.8 8.1 27.4 11.0 32.3 PRKDC "DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, p350, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic polypeptide" P78527 8 47773108-47960183 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, Ribosome biogenesis" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm NA NA 1100000 Nucleoplasm "CAB005167: AB_2172845, HPA035174: AB_2674504" "unprognostic (3.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (7.70e-3)" "unprognostic (5.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.60e-2)" "unprognostic (7.76e-3)" "unprognostic (7.77e-2)" "unprognostic (2.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (2.15e-2)" 21.3 20.5 16.0 22.3 22.0 27.4 30.2 16.5 23.1 19.6 20.6 17.3 18.1 12.0 26.2 14.5 27.4 24.4 13.0 21.1 20.8 15.2 16.7 18.4 17.0 33.6 16.6 18.2 24.6 23.8 33.4 29.4 20.5 17.3 17.9 20.3 17.8 17.9 17.8 34.0 23.9 18.4 27.0 20.3 24.4 19.1 20.5 15.9 44.4 20.8 15.9 27.9 21.3 19.1 17.0 13.9 7.1 11.5 11.5 11.3 2.3 32.9 28.2 27.5 26.1 17.1 18.2 11.6 14.0 13.8 19.8 19.5 18.4 10.9 31.5 12.2 17.2 14.7 18.8 36.3 19.2 31.0 6.9 22.5 61.8 25.4 22.5 7.4 23.5 12.9 13.1 6.3 31.1 32.7 7.6 20.3 21.9 41.1 13.3 21.8 15.5 33.1 19.4 30.2 23.1 8.6 16.2 21.6 11.1 9.9 28.4 13.8 17.5 43.3 14.1 13.6 17.7 20.2 16.2 23.5 25.9 22.0 20.4 28.1 11.6 14.8 45.3 14.6 26.7 20.9 6.7 8.1 3.5 8.7 6.3 10.9 12.6 10.8 8.8 5.9 17.0 11.3 10.3 7.1 11.5 11.5 13.9 7.4 2.3 16.0 22.0 16.5 23.1 20.8 15.2 16.6 18.2 17.3 15.9 35.7 26.0 39.5 30.4 34.1 100.6 65.8 25.5 52.2 39.8 40.1 117.8 48.3 14.9 34.6 26.1 40.5 10.5 0.0 30.9 53.5 37.0 37.2 43.9 39.8 32.1 98.5 24.8 33.7 41.6 10.8 52.6 32.7 18.6 29.7 26.8 69.1 30.3 14.0 65.4 18.7 102.0 51.8 28.8 106.0 117.5 35.5 27.6 38.3 45.0 27.8 PRKG1 "PGK, PKG, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase, cGMP-dependent, type I" Q13976 10 50990891-52298350 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 43.8;Late spermatids: 40.9;Peritubular cells: 37.1;Sertoli cells: 38.8;Smooth muscle cells: 47.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21 "basophil: 8.0" "Lineage enriched" "Detected in single" 24 "granulocytes: 8.0" "Cell line enhanced" "Detected in many" "AN3-CA: 11.6;BJ hTERT+: 15.9;fHDF/TERT166: 13.1;U-138 MG: 9.7;U-87 MG: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol NA NA 33000 "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 8.0 10.9 5.2 6.6 7.3 0.8 6.9 2.8 5.4 19.2 14.4 2.1 6.8 2.9 22.8 10.7 6.0 9.9 12.6 14.8 7.0 4.9 4.4 2.1 19.5 2.6 3.1 4.8 8.9 2.6 13.7 8.4 11.0 4.6 9.5 6.2 6.2 6.4 9.4 24.9 2.8 5.3 28.2 2.7 2.7 5.9 5.0 3.1 0.2 9.2 12.7 1.2 13.4 15.8 0.1 0.1 8.0 0.1 0.3 0.0 0.1 0.0 0.1 1.5 11.6 5.6 5.3 0.0 5.0 15.9 1.6 2.4 0.1 0.8 0.2 0.0 13.1 1.7 0.1 0.0 0.0 1.5 0.0 4.3 0.8 0.3 0.0 4.8 0.0 0.0 6.8 0.0 4.2 0.1 0.4 0.0 0.0 0.0 0.1 4.4 0.1 0.0 0.0 3.3 0.0 2.0 0.0 3.1 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.1 1.6 0.1 0.0 0.0 9.7 1.7 4.9 2.9 1.2 0.6 0.0 8.6 0.0 2.0 8.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.1 5.2 7.3 2.8 5.4 7.0 4.9 3.1 4.8 4.6 3.1 14.9 9.6 0.0 1.4 0.8 6.8 29.7 0.0 1.4 0.0 3.5 0.0 0.8 0.0 1.8 43.8 3.7 2.6 0.0 3.3 0.9 13.0 0.4 4.6 0.0 0.3 0.0 0.0 4.3 0.0 40.9 30.2 0.3 3.3 0.0 4.3 23.0 3.5 11.4 37.1 0.0 1.3 38.8 47.0 0.7 0.6 0.5 1.8 0.0 3.2 0.7 PRKG2 "cGKII, PRKGR2" ENSG00000138669 "Protein kinase, cGMP-dependent, type II" Q13237 4 81087370-81215117 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.3" "Cell type enhanced" "Detected in some" 22 "Alveolar cells type 1: 32.8;Enterocytes: 13.8;Paneth cells: 8.6" "Cancer enhanced" "Detected in some" "melanoma: 4.1" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "basophil: 2.0;MAIT T-cell: 2.2" "Group enriched" "Detected in many" 4 "granulocytes: 2.0;T-cells: 2.2" "Cell line enhanced" "Detected in some" "ASC diff: 5.2;ASC TERT1: 4.0;HEL: 20.8;hTCEpi: 4.1;SCLC-21H: 6.4" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved NA NA "CAB018739: AB_2284387, HPA007386: AB_1079678" "unprognostic (6.14e-2)" "unprognostic (2.77e-1)" "unprognostic (2.14e-1)" "unprognostic (5.01e-4)" "unprognostic (4.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.13e-1)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (4.00e-3)" "unprognostic (1.06e-1)" 4.7 0.4 5.2 0.4 2.9 0.6 2.2 0.8 5.3 1.4 7.7 1.2 0.7 12.2 0.6 0.6 3.8 0.6 0.4 6.3 2.9 3.3 0.7 0.3 4.3 0.3 2.5 1.9 0.3 1.8 0.0 12.1 0.2 9.3 12.7 3.8 1.4 0.8 4.6 0.3 2.1 34.3 0.7 1.3 0.3 1.3 1.7 2.4 0.0 1.3 0.0 0.6 1.2 1.3 0.4 0.0 2.0 0.0 0.4 2.2 0.4 0.1 0.3 0.1 0.0 5.2 4.0 0.0 0.3 0.0 0.0 0.0 0.4 2.4 0.0 0.2 0.9 0.0 0.1 0.3 1.6 0.0 0.4 0.0 20.8 0.6 0.0 0.0 0.0 0.0 0.6 4.1 0.0 0.0 1.1 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.1 0.0 0.9 6.4 0.0 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 2.2 0.2 0.5 0.3 0.0 0.4 0.8 0.9 0.0 0.4 0.0 0.0 0.0 0.4 5.2 2.9 0.8 5.3 2.9 3.3 2.5 1.9 9.3 2.4 32.8 1.6 0.0 0.6 0.0 0.0 2.6 0.0 1.4 3.4 0.0 0.0 0.0 0.0 0.1 5.3 0.0 13.8 0.0 0.0 0.1 0.0 0.7 1.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.0 0.6 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.2 PRKX PKX1 ENSG00000183943 "Protein kinase, X-linked" P51817 X 3604370-3713608 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "granulocytes: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 38.8" "Low region specificity" "Detected in all" HPA015324 Supported Supported Nucleoplasm No No Nucleoplasm "HPA015324: AB_1855715" "unprognostic (1.07e-1)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.63e-1)" "unprognostic (2.45e-1)" "unprognostic (3.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.33e-2)" "unprognostic (4.14e-1)" "unprognostic (1.68e-1)" "unprognostic (2.68e-1)" "unprognostic (2.92e-1)" "unprognostic (1.07e-3)" "unprognostic (2.15e-2)" "unprognostic (9.91e-2)" "unprognostic (2.52e-1)" "unprognostic (1.70e-2)" 4.3 1.3 12.3 7.5 15.8 5.4 11.2 4.4 12.3 6.9 5.2 5.4 11.5 4.1 7.3 8.4 13.6 16.5 3.9 4.0 14.0 7.4 14.2 2.0 8.4 9.5 27.9 5.6 4.8 4.1 3.2 2.3 6.6 22.7 3.7 5.2 3.1 6.5 5.3 1.6 9.9 6.0 3.0 17.6 10.0 3.1 6.1 22.7 6.1 28.8 3.2 8.0 3.7 11.2 2.5 2.8 12.2 4.1 3.3 3.8 1.7 4.5 4.2 11.6 8.6 2.2 3.0 10.6 2.7 1.0 1.3 1.8 6.2 3.1 0.4 2.7 2.1 2.8 3.1 10.7 8.1 2.3 5.0 7.5 5.0 3.2 0.1 2.3 6.4 38.8 2.0 8.7 1.4 5.3 3.7 13.1 6.3 5.8 6.5 4.4 3.9 7.3 5.7 7.7 3.5 4.8 13.7 11.1 8.5 10.7 3.8 7.8 5.0 2.8 1.8 2.7 19.0 1.4 5.1 7.1 1.2 2.0 1.9 1.8 0.1 0.3 5.8 0.7 5.8 3.0 12.2 3.1 1.8 3.5 3.3 3.8 2.5 3.7 3.3 2.3 2.4 3.1 3.3 0.8 3.3 4.1 2.8 2.5 1.7 12.3 15.8 4.4 12.3 14.0 7.4 27.9 5.6 22.7 22.7 3.0 13.1 6.5 16.9 19.1 0.6 1.4 25.5 17.4 9.1 5.2 0.0 17.4 11.6 10.4 7.2 17.0 7.7 0.0 2.7 3.8 9.7 9.1 85.2 1.7 15.1 1.6 4.6 11.1 19.0 34.3 18.4 20.8 5.0 6.4 11.4 2.1 4.7 10.5 20.5 5.1 0.7 32.3 22.0 1.6 21.7 23.5 6.5 25.5 22.2 16.5 PRPF4B "KIAA0536, PR4H, Prp4" ENSG00000112739 "Pre-mRNA processing factor 4B" Q13523 6 4021267-4064983 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020638 Approved Supported "Nuclear speckles" NA NA "Nuclear speckles" "HPA020638: AB_1855774" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (4.95e-2)" "unprognostic (2.20e-1)" "unprognostic (3.59e-3)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (8.68e-3)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.50e-3)" "unprognostic (8.90e-2)" "unprognostic (2.34e-1)" "unprognostic (7.63e-3)" "prognostic favorable (6.82e-5)" 23.2 21.6 19.6 24.0 20.5 8.5 21.4 35.6 26.8 18.3 19.3 6.0 14.7 12.0 22.2 14.2 23.6 14.7 13.6 16.3 16.5 11.7 15.0 14.5 13.0 15.4 14.5 14.1 19.1 14.4 20.9 30.9 17.1 21.0 14.9 15.7 5.3 22.7 20.4 45.7 16.3 16.4 14.9 23.7 19.0 13.6 11.6 20.2 21.8 21.1 11.3 17.4 21.4 22.2 9.7 13.6 7.5 11.9 11.8 9.1 3.9 14.7 12.8 20.2 13.8 11.5 10.7 9.8 14.3 15.7 15.6 15.8 12.2 7.5 24.1 18.0 16.1 12.8 13.2 25.4 12.4 22.5 11.3 18.6 27.1 14.7 10.9 8.8 29.9 14.8 9.7 8.2 11.1 6.9 7.6 15.5 11.8 37.1 8.9 15.3 8.6 21.9 10.0 12.1 12.9 11.9 24.9 19.5 23.4 10.0 16.6 15.7 10.3 16.6 10.4 12.6 16.8 16.2 15.0 16.6 15.4 8.9 10.1 13.8 10.1 15.8 28.1 8.4 13.7 18.7 7.5 11.9 3.6 7.6 9.9 9.1 9.7 8.6 9.0 10.2 9.3 8.0 8.0 6.1 11.8 8.7 13.6 6.3 3.9 19.6 20.5 35.6 26.8 16.5 11.7 14.5 14.1 21.0 20.2 101.3 91.8 89.2 53.8 74.1 81.8 69.0 61.1 89.7 101.2 92.5 84.4 51.4 61.3 56.7 8.7 82.4 58.2 46.7 49.5 40.6 50.2 53.8 86.8 76.7 36.1 100.1 72.3 68.2 59.0 11.9 91.5 57.7 33.7 71.3 57.5 80.9 52.5 57.5 83.8 50.1 181.0 58.2 43.9 67.7 79.4 79.8 53.2 69.3 57.5 63.7 PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893272-67929678 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053927, HPA062763" Approved Supported "Nuclear speckles,Cytosol" NA NA "Nuclear speckles" Cytosol "HPA053927: AB_2682312, HPA062763: " "unprognostic (2.57e-2)" "unprognostic (8.91e-3)" "unprognostic (1.88e-1)" "unprognostic (5.79e-2)" "unprognostic (3.26e-1)" "unprognostic (3.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.66e-2)" "unprognostic (9.85e-3)" "unprognostic (8.32e-2)" "prognostic favorable (4.28e-10)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (4.15e-2)" "unprognostic (3.90e-3)" 14.3 18.3 13.6 14.0 16.6 4.8 15.1 13.3 13.3 11.0 14.7 17.7 24.0 14.0 19.2 14.6 17.7 20.2 19.3 17.8 12.2 8.4 18.8 15.1 13.1 10.4 16.2 12.7 21.2 35.3 33.2 13.0 9.8 16.1 14.3 11.4 16.2 19.0 14.8 19.9 14.0 15.2 16.3 11.3 12.8 19.1 31.7 15.0 12.5 14.9 12.9 8.6 14.8 18.7 4.0 5.2 4.5 5.8 5.2 5.6 3.5 7.4 13.3 15.2 16.7 23.6 12.0 9.8 9.0 13.7 9.6 8.5 10.0 10.8 7.0 13.7 15.1 7.6 11.3 8.7 9.2 3.2 2.7 9.8 8.0 9.9 12.7 16.2 7.6 4.8 22.0 16.1 11.3 11.9 12.9 13.9 13.3 12.2 3.0 9.9 16.6 10.3 4.9 14.5 8.1 8.3 15.9 5.8 14.5 11.2 9.3 13.2 15.7 27.9 7.6 9.1 6.3 14.0 13.9 12.2 10.8 3.8 9.0 4.5 9.2 4.9 15.2 13.0 5.1 11.8 0.0 4.3 4.5 5.6 5.8 3.8 4.0 3.9 5.3 5.2 3.5 3.4 4.3 2.7 5.2 3.6 3.8 2.3 3.5 13.6 16.6 13.3 13.3 12.2 8.4 16.2 12.7 16.1 15.0 0.0 2.2 5.1 2.5 1.0 10.7 1.7 7.6 4.0 2.3 5.2 5.9 5.2 10.0 5.5 10.8 2.9 8.1 0.0 6.5 4.0 3.9 3.5 5.8 7.7 4.1 6.4 10.4 4.3 5.6 16.9 4.4 1.2 5.0 3.6 6.3 8.2 6.9 3.5 7.4 6.3 6.7 12.9 4.7 3.5 5.7 1.4 4.9 3.1 6.3 1.4 PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86048373-86088621 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "kidney: 1.9;placenta: 1.2;testis: 2.0" "Cell type enhanced" "Detected in single" 35 "Rod photoreceptor cells: 1.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "HEL: 14.3" "HPA015095, HPA056839" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: AB_1855815, HPA056839: " "unprognostic (1.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA 32000 "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 22.6 20.4 36.0 14.4 42.3 3.1 19.3 20.5 40.8 24.9 17.9 55.7 23.5 14.5 20.2 29.9 14.6 18.7 18.4 20.0 43.5 23.9 22.3 17.0 21.5 13.0 41.4 31.4 19.4 18.2 33.1 13.0 42.1 30.0 19.2 20.7 11.0 21.9 25.5 17.9 13.5 16.3 21.9 38.0 12.2 17.5 21.2 46.1 2.8 22.5 10.2 14.0 22.2 17.8 8.6 7.2 1.8 3.9 5.2 5.7 4.1 14.5 23.1 32.1 11.5 13.5 14.5 20.7 14.4 20.0 13.4 13.2 10.1 12.0 8.8 32.6 18.3 18.9 17.1 18.8 32.8 20.4 0.1 8.8 19.5 12.8 13.9 18.5 0.0 9.2 9.8 16.2 16.8 23.7 35.4 39.6 12.5 19.6 0.2 17.9 25.2 0.2 0.1 12.4 31.5 25.8 12.9 17.6 0.4 28.4 33.1 12.7 15.9 22.4 7.2 14.5 29.6 17.0 0.3 23.9 13.3 25.0 15.6 16.1 0.0 0.1 0.9 17.2 0.1 17.9 1.8 3.9 0.0 0.3 1.6 0.0 6.8 0.8 0.1 5.3 8.6 5.7 2.0 1.7 5.2 0.9 7.2 0.2 4.1 36.0 42.3 20.5 40.8 43.5 23.9 41.4 31.4 30.0 46.1 29.8 24.9 2.7 51.7 29.7 51.6 26.2 33.1 25.4 20.5 52.4 56.9 27.2 19.9 23.3 34.0 35.8 21.0 0.0 20.0 45.5 28.2 67.2 9.2 14.7 6.8 63.5 24.8 33.7 11.7 33.3 22.2 7.9 23.6 1.0 23.1 41.5 33.4 21.0 20.5 22.6 56.8 97.0 121.7 43.2 62.8 22.6 27.8 1.8 21.0 67.4 PTK2B "CADTK, CAKB, FAK2, PTK, PYK2, RAFTK" ENSG00000120899 "Protein tyrosine kinase 2 beta" Q14289 8 27311482-27459391 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.7;brain: 65.2" "Cell type enhanced" "Detected in many" 5 "Kupffer cells: 73.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 37.7;REH: 41.9" "Group enriched" "Detected in many" 4 "amygdala: 202.9;basal ganglia: 236.9;cerebral cortex: 189.7;hippocampal formation: 443.3;olfactory region: 185.5" "Low region specificity" "Detected in all" "CAB003850, HPA026091, HPA026276" Approved Supported "Plasma membrane,Cytosol" NA NA 84000 "Plasma membrane, Cytosol" "CAB003850: AB_562205, HPA026091: AB_10599739, HPA026276: AB_10601234" "unprognostic (2.36e-2)" "prognostic favorable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (7.36e-3)" "unprognostic (3.72e-2)" "unprognostic (3.11e-2)" "unprognostic (2.70e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-2)" "unprognostic (3.32e-1)" "unprognostic (2.40e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "prognostic favorable (5.11e-4)" "unprognostic (3.33e-3)" 7.2 4.7 20.4 24.3 30.0 46.7 4.9 65.2 48.3 5.4 14.5 7.8 5.0 16.6 4.3 4.7 7.9 6.8 6.4 4.7 30.5 7.0 6.8 5.0 11.5 35.6 4.3 25.4 2.4 5.4 5.2 5.3 4.1 3.9 10.1 11.9 8.3 12.6 6.7 2.2 15.1 18.4 5.5 4.8 32.0 10.8 4.3 3.7 37.8 5.6 2.9 35.4 13.0 6.0 26.9 18.7 24.0 25.8 14.7 19.0 21.5 11.1 3.1 0.8 0.9 24.0 1.7 6.5 0.9 0.6 0.6 0.8 2.9 6.5 37.7 1.2 1.7 0.9 10.3 0.3 9.4 0.3 2.5 0.2 7.8 3.0 0.6 4.9 8.3 14.0 13.0 14.0 0.8 5.4 4.0 0.3 10.9 9.1 26.3 0.6 1.1 14.3 16.8 0.6 9.7 0.8 41.9 0.2 25.8 2.6 8.8 6.0 1.1 4.0 2.8 1.5 2.1 3.3 21.6 5.3 0.4 0.8 0.7 0.3 21.1 9.1 20.4 1.6 18.1 0.7 22.3 23.7 18.0 19.0 22.4 12.5 25.5 9.6 13.3 18.7 26.9 12.1 14.2 24.0 14.7 25.8 6.2 9.5 21.5 20.4 30.0 65.2 48.3 30.5 7.0 4.3 25.4 3.9 3.7 3.0 30.9 54.0 32.1 33.5 4.1 3.1 12.7 13.4 13.6 14.0 0.0 2.4 0.0 6.4 1.1 7.5 48.3 0.0 7.0 23.9 3.8 16.5 27.7 21.8 20.9 7.9 7.5 3.1 73.4 0.8 1.4 42.5 8.5 34.3 18.6 3.4 9.4 35.1 0.7 14.7 4.0 0.0 1.6 4.2 5.5 26.3 1.6 39.9 14.9 14.8 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537370 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.0;intestine: 24.2;skin 1: 24.2" "Cell type enhanced" "Detected in many" 12 "Alveolar cells type 2: 34.1;Enterocytes: 90.1;Mucus-secreting cells: 39.1;Paneth cells: 65.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 10.6;CAPAN-2: 20.4;HaCaT: 16.6;hTCEpi: 22.5;OE19: 27.4;RT4: 13.0;T-47d: 12.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.7 0.0 0.4 5.3 0.4 0.0 1.7 0.4 0.4 7.6 18.1 0.5 0.8 13.6 0.6 0.5 44.0 0.0 11.7 0.4 0.4 0.0 0.8 1.7 1.1 0.4 0.4 0.4 0.4 1.4 0.0 0.4 0.6 0.4 2.2 7.4 0.4 7.6 0.4 0.4 24.2 24.2 0.9 0.4 0.4 12.5 0.4 0.4 0.4 0.4 18.9 17.2 6.5 15.0 1.3 4.5 1.2 2.4 0.3 1.9 0.9 10.6 1.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 20.4 0.0 3.6 0.0 0.0 16.6 0.0 0.0 0.0 2.6 0.2 0.0 4.3 0.0 0.0 0.0 3.4 0.0 22.5 0.0 0.1 0.1 0.0 0.0 0.1 1.2 0.1 5.9 0.0 0.1 0.1 27.4 7.7 0.0 0.6 0.2 0.0 13.0 0.1 1.1 1.2 4.0 0.0 0.0 12.5 0.8 0.1 0.1 0.2 0.4 0.1 0.2 0.0 0.0 0.2 0.2 0.5 1.2 2.4 0.4 0.5 1.7 1.9 1.2 0.4 0.1 4.5 1.3 0.4 0.6 1.2 0.3 1.3 0.3 0.5 0.9 0.4 0.4 0.4 0.4 0.4 0.0 0.4 0.4 0.4 0.4 11.9 34.1 0.0 2.8 5.3 2.0 0.4 12.7 9.4 17.0 0.0 2.0 0.2 0.0 1.4 0.0 0.3 90.1 0.0 1.4 0.1 0.4 1.3 9.2 1.5 0.7 0.0 5.2 0.6 4.1 0.0 0.3 2.8 0.0 0.0 39.1 2.4 10.3 65.1 0.0 0.1 3.9 0.0 0.4 0.2 0.2 13.6 0.1 0.0 18.8 13.8 PTK7 CCK4 ENSG00000112655 "Protein tyrosine kinase 7 (inactive)" Q13308 6 43076268-43161719 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Early spermatids: 314.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 9 "plasmacytoid DC: 13.8" "Lineage enriched" "Detected in many" 9 "dendritic cells: 13.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003222 Approved "Secreted to blood" NA NA 10000000 "HPA003222: AB_1079713" "unprognostic (1.80e-1)" "unprognostic (7.49e-3)" "unprognostic (6.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.15e-2)" "unprognostic (5.85e-3)" "unprognostic (9.81e-3)" "unprognostic (1.47e-3)" "unprognostic (7.15e-2)" "unprognostic (5.11e-3)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (9.12e-2)" "unprognostic (5.70e-3)" 5.4 1.8 1.4 3.5 3.4 0.8 12.2 3.5 4.9 30.9 4.8 3.4 8.9 2.1 37.7 36.9 11.7 14.3 14.5 3.5 2.2 3.9 10.1 0.8 18.7 4.3 1.3 2.7 42.6 16.3 9.0 9.0 20.9 4.2 18.2 3.3 13.9 15.0 10.9 0.4 13.6 3.4 16.4 3.2 12.4 4.6 14.9 1.4 28.7 19.3 8.1 6.2 9.5 17.6 0.0 13.8 0.3 0.0 0.7 1.5 0.8 2.1 0.6 21.1 35.0 22.7 23.3 30.0 22.6 36.5 19.8 25.4 19.0 7.6 0.0 17.9 26.3 14.4 24.5 9.4 21.5 12.6 0.1 11.7 2.0 4.3 25.5 34.5 0.0 0.1 33.3 19.5 26.1 8.3 34.6 2.5 8.5 1.3 0.0 9.0 1.6 7.6 3.0 9.8 0.2 1.7 7.7 30.0 0.0 15.3 10.5 12.1 23.0 3.6 0.3 11.7 23.2 12.9 4.6 1.6 21.2 13.4 0.1 12.2 0.1 0.2 0.7 4.9 0.0 3.5 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.1 1.5 0.2 0.7 0.0 13.8 0.0 0.8 1.4 3.4 3.5 4.9 2.2 3.9 1.3 2.7 4.2 1.4 14.9 12.5 0.0 16.8 15.3 1.4 1.6 2.5 2.7 6.8 12.2 53.0 18.9 1.7 19.2 314.6 1.0 0.2 0.0 6.2 1.9 31.6 10.9 1.1 0.0 3.1 0.0 20.7 1.8 0.0 38.8 17.0 1.1 15.1 1.0 1.2 19.8 8.6 3.5 17.3 0.5 1.7 12.9 9.5 2.4 18.5 9.2 6.9 0.7 2.6 9.7 PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426126 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 81.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 48.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Approved Supported "Plasma membrane,Centriolar satellite,Cytosol" NA NA Cytosol "Plasma membrane, Centriolar satellite" "HPA024068: AB_1855967" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-3)" "unprognostic (5.03e-3)" "prognostic favorable (5.68e-4)" "unprognostic (3.90e-1)" "unprognostic (8.09e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" 9.3 9.4 20.7 17.0 51.4 33.6 7.6 22.6 31.4 28.9 8.9 81.1 2.4 6.3 14.2 5.3 6.6 8.0 9.6 7.5 33.7 19.9 10.4 5.7 8.2 23.8 68.6 23.4 11.1 8.5 13.7 6.1 17.5 43.9 6.0 6.4 4.4 8.8 7.7 7.6 7.5 7.7 11.8 55.9 13.5 8.3 6.7 56.6 3.7 40.3 2.5 26.1 9.8 13.1 31.3 18.8 31.8 22.5 8.7 11.2 13.4 4.3 2.5 1.9 3.5 26.9 23.9 5.7 6.9 14.7 6.7 9.4 1.2 0.9 22.8 1.6 11.7 9.7 1.3 6.0 4.4 7.1 5.7 3.8 3.9 3.1 1.7 31.4 33.9 6.9 20.4 10.6 8.4 14.6 23.6 5.9 14.6 4.8 7.5 12.0 1.6 7.4 35.0 2.3 1.3 6.3 12.8 3.3 4.1 4.2 2.4 1.7 1.2 4.7 3.4 5.5 3.6 11.5 35.1 6.0 8.4 3.5 15.9 7.3 5.9 5.8 22.7 12.1 48.2 3.5 14.6 20.1 29.4 11.2 16.2 9.9 29.0 8.1 9.4 18.8 31.3 7.1 8.4 31.8 8.7 22.5 13.5 8.7 13.4 20.7 51.4 22.6 31.4 33.7 19.9 68.6 23.4 43.9 56.6 8.9 4.6 34.0 4.9 12.6 29.2 11.8 7.6 8.1 6.8 22.7 19.6 13.3 28.2 5.9 60.8 14.3 6.3 23.3 5.0 6.5 30.9 6.4 19.6 6.8 12.0 19.1 7.5 18.4 24.8 27.6 28.4 16.3 16.9 8.2 5.2 29.3 3.5 3.5 23.7 9.1 20.8 19.4 15.5 14.0 19.4 11.4 29.4 15.9 4.4 3.2 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664226 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 53.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002640, CAB019291" Approved Approved "Nuclear speckles" NA NA "Nuclear speckles" "CAB019291: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 19.5 15.6 15.1 14.7 17.1 32.2 17.5 35.2 18.9 19.9 20.3 21.1 19.6 18.4 24.9 15.7 24.6 18.6 20.2 39.3 15.3 11.0 21.7 36.2 19.7 15.7 16.0 13.4 24.9 31.3 30.7 16.9 24.8 14.3 18.8 19.2 25.0 18.3 18.4 79.7 23.9 29.6 23.7 13.8 22.1 23.7 16.7 17.8 27.7 26.9 27.9 26.1 20.5 20.4 6.6 9.3 53.9 9.9 8.5 8.6 7.7 15.4 17.8 27.1 21.0 23.6 19.1 54.6 23.6 40.0 31.3 35.5 13.9 12.8 16.2 11.3 36.5 16.9 9.9 28.5 20.9 32.6 28.3 22.4 21.8 21.4 12.9 23.9 21.2 20.7 17.6 21.2 32.2 26.1 21.6 22.4 24.9 15.8 42.6 30.1 26.4 27.2 15.7 27.6 19.3 24.2 22.0 23.8 20.4 18.7 23.4 8.5 17.8 19.3 18.7 12.5 22.0 31.0 28.1 16.0 21.5 20.5 18.0 26.2 33.2 52.9 34.9 18.5 24.8 22.8 11.3 9.7 18.4 7.4 9.9 7.5 6.6 7.3 7.2 9.3 6.3 7.5 7.6 53.9 8.5 9.6 4.2 8.6 7.7 15.1 17.1 35.2 18.9 15.3 11.0 16.0 13.4 14.3 17.8 20.8 36.5 39.7 31.1 30.6 51.6 25.8 28.1 25.4 21.6 26.2 62.8 34.3 11.6 22.9 7.1 29.1 32.5 0.0 32.0 39.8 32.9 38.2 33.5 36.5 25.2 41.3 28.2 31.3 36.8 3.4 36.2 34.2 25.3 29.7 29.6 32.1 28.8 34.8 38.9 15.7 84.2 32.3 33.0 17.7 27.4 38.0 52.1 38.3 29.5 36.9 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077027-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 63.9" "Cell type enriched" "Detected in some" 44 "Horizontal cells: 74.7" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "non-classical monocyte: 6.7" "Group enriched" "Detected in many" 13 "dendritic cells: 2.1;monocytes: 6.7" "Cell line enhanced" "Detected in some" "MCF7: 18.0;NB-4: 11.8;SH-SY5Y: 91.8;THP-1: 27.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "midbrain: 95.5" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 260000 "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 15.2 1.1 1.8 1.3 0.7 1.2 4.1 9.0 1.9 3.1 0.9 1.1 1.5 0.9 0.6 1.2 0.7 1.0 1.2 1.5 5.8 1.0 11.7 0.7 0.8 17.5 1.2 0.8 1.3 63.9 6.3 0.8 16.8 2.2 1.5 2.8 13.6 2.0 4.5 1.1 2.6 1.1 2.8 0.6 2.1 2.0 0.0 0.1 0.8 5.1 0.6 1.9 1.4 0.2 2.1 0.0 6.7 0.0 0.3 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 11.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 91.8 0.0 0.0 0.0 0.1 1.3 27.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 6.7 2.1 0.3 0.4 1.1 1.3 4.1 9.0 1.5 5.8 17.5 1.2 16.8 0.0 0.0 0.3 0.0 0.5 0.2 0.1 1.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.2 1.7 1.0 1.2 1.1 0.8 0.1 74.7 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.4 1.1 0.5 0.0 0.0 0.0 0.1 RIOK1 "AD034, bA288G3.1, FLJ30006, RRP10" ENSG00000124784 "RIO kinase 1" Q9BRS2 6 7389496-7418037 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Spermatogonia: 78.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017866, HPA051446" Enhanced Supported Cytosol NA NA Cytosol "HPA017866: AB_2669670, HPA051446: AB_2681488" "unprognostic (2.33e-2)" "unprognostic (1.24e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.41e-5)" "unprognostic (2.23e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (3.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.85e-5)" "unprognostic (2.33e-1)" "unprognostic (2.09e-1)" "unprognostic (6.12e-3)" "unprognostic (2.59e-2)" 13.8 10.6 7.7 13.2 13.0 17.5 13.1 12.2 13.5 12.7 11.6 7.3 4.0 7.3 15.4 6.0 15.6 12.3 8.5 11.8 8.0 8.1 8.7 11.7 10.1 14.2 11.6 9.4 13.8 15.3 7.7 17.8 13.9 13.3 10.7 9.6 7.2 10.2 10.3 18.8 12.5 9.9 15.5 9.4 14.4 10.3 21.3 9.2 19.2 10.1 14.7 16.8 10.9 12.6 15.4 14.9 7.7 11.1 18.6 15.0 8.2 7.6 4.4 7.2 16.8 11.2 9.2 11.0 9.6 6.5 9.0 7.4 12.9 3.9 19.9 17.1 7.8 7.8 7.8 18.1 7.7 11.5 13.1 19.5 10.6 7.1 13.8 9.5 30.5 13.9 6.8 10.7 9.7 20.0 4.3 7.9 15.0 27.0 4.7 8.4 10.0 20.7 14.5 15.4 14.2 10.5 15.9 9.4 21.6 5.0 7.4 24.0 11.8 8.1 4.9 14.0 19.4 7.4 10.1 7.9 9.8 7.4 6.5 14.5 6.4 12.2 29.6 3.0 15.7 15.0 7.7 8.5 5.9 11.5 11.1 13.8 15.2 11.9 12.1 14.9 15.4 13.7 15.0 1.7 18.6 9.7 12.4 11.3 8.2 7.7 13.0 12.2 13.5 8.0 8.1 11.6 9.4 13.3 9.2 6.0 26.6 22.4 26.7 46.9 9.2 20.4 2.5 25.4 45.5 7.0 9.8 29.8 3.3 13.2 34.2 23.9 5.8 0.0 10.2 28.8 22.0 11.9 32.4 8.9 20.4 4.8 6.9 17.2 6.5 6.5 18.4 16.7 16.9 11.8 10.4 5.5 10.9 5.8 18.7 9.0 10.4 19.4 26.4 55.6 78.8 56.7 23.3 22.0 15.3 20.6 RIOK2 FLJ11159 ENSG00000058729 "RIO kinase 2" Q9BVS4 5 97160867-97183260 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA005681 Uncertain Approved "Plasma membrane,Cytosol" NA NA Cytosol "Plasma membrane" "HPA005681: AB_1856286" "unprognostic (6.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-2)" "unprognostic (8.04e-2)" "unprognostic (1.38e-1)" "unprognostic (4.51e-2)" "unprognostic (2.71e-3)" "unprognostic (3.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.11e-1)" "unprognostic (8.76e-2)" "unprognostic (6.63e-2)" "unprognostic (1.26e-3)" "unprognostic (3.60e-1)" "unprognostic (9.98e-2)" "unprognostic (1.43e-2)" "unprognostic (1.39e-2)" 22.2 20.1 14.8 17.1 17.5 24.4 19.7 26.3 18.6 19.1 17.0 8.9 14.0 17.3 17.5 17.1 17.0 15.0 10.7 19.6 15.7 13.4 21.0 23.6 13.3 17.6 20.0 11.1 20.7 21.5 15.1 37.5 15.8 19.7 19.5 17.3 10.3 18.7 16.6 24.9 13.3 20.2 16.3 20.7 22.5 16.4 14.8 18.6 25.8 21.7 20.7 17.4 20.7 21.0 15.2 17.8 9.4 18.7 17.8 24.1 13.5 8.8 10.4 9.7 18.8 12.8 14.0 15.5 22.3 13.8 15.8 21.0 14.2 15.6 19.6 25.4 10.0 24.9 10.5 16.5 13.0 21.7 13.8 9.1 9.8 20.1 19.8 11.5 18.6 13.8 9.2 10.2 19.3 19.6 12.1 12.8 14.6 14.8 12.7 18.1 14.8 21.8 22.3 11.5 5.3 11.2 24.5 18.9 28.8 12.4 8.1 12.1 9.0 13.5 14.1 15.4 15.1 14.7 17.8 13.7 20.3 14.1 16.1 24.3 12.5 16.2 44.0 12.1 19.1 18.5 7.0 16.0 9.4 16.3 18.7 22.3 15.2 20.7 17.8 17.8 11.0 22.5 24.1 3.2 17.8 13.4 17.8 18.5 13.5 14.8 17.5 26.3 18.6 15.7 13.4 20.0 11.1 19.7 18.6 8.9 10.9 13.0 14.3 23.5 16.4 15.9 12.7 10.7 11.4 7.0 11.8 16.7 14.9 14.2 1.1 14.0 7.0 0.0 13.1 19.4 15.8 9.9 27.6 7.8 15.9 12.7 9.2 6.2 11.0 1.8 12.4 11.5 5.0 13.6 11.2 12.3 10.5 10.5 15.2 12.2 17.2 6.5 21.7 20.7 20.2 16.6 14.5 14.4 12.1 11.4 RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23452823-23486603 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: AB_1079815, HPA024184: AB_1856289" "unprognostic (7.99e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.48e-2)" "unprognostic (8.98e-3)" "unprognostic (1.01e-1)" "unprognostic (5.10e-2)" "unprognostic (4.20e-1)" "prognostic unfavorable (4.10e-4)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (5.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.71e-2)" 10.1 8.7 6.9 11.7 7.7 52.4 10.9 8.9 10.1 14.7 21.4 8.5 5.9 15.6 8.8 9.3 41.0 7.8 10.7 11.5 6.1 5.5 10.5 19.9 10.1 10.7 9.1 6.2 7.6 10.7 7.5 11.6 21.4 11.6 6.8 14.7 6.0 14.9 7.0 40.0 13.3 36.5 15.2 10.5 8.9 12.9 22.7 7.6 11.1 7.3 16.0 16.5 13.7 21.5 11.7 11.0 21.7 21.5 8.3 11.2 10.0 14.8 5.8 6.1 7.9 11.1 12.4 11.0 14.9 11.0 10.6 10.2 6.7 16.1 10.3 19.6 16.6 10.8 19.5 10.3 17.0 16.4 10.2 4.3 9.6 10.9 8.4 27.8 27.0 8.4 14.8 32.4 18.8 26.0 12.1 14.7 6.5 13.9 13.0 15.9 7.9 9.3 4.4 5.6 21.7 11.7 10.5 12.7 12.5 12.1 19.5 14.2 10.2 19.1 8.7 10.9 15.9 7.7 14.6 23.1 17.5 4.4 7.7 9.6 23.5 19.7 15.3 10.3 12.5 13.1 21.7 13.5 8.0 9.1 19.6 6.9 8.2 7.6 7.9 11.0 11.7 6.1 6.9 9.3 8.3 21.5 5.1 11.2 10.0 6.9 7.7 8.9 10.1 6.1 5.5 9.1 6.2 11.6 7.6 74.5 51.9 21.7 78.2 107.0 43.0 61.7 43.3 56.2 67.1 24.4 53.0 38.5 21.6 40.3 191.3 39.6 193.3 116.8 45.8 56.7 46.6 92.4 61.2 72.5 37.1 27.0 60.3 33.7 55.0 227.3 20.8 49.5 40.5 47.7 85.9 17.1 98.8 75.8 28.3 40.3 43.8 6.5 38.7 23.6 9.5 125.6 73.9 34.1 42.3 194.9 RIPK1 RIP ENSG00000137275 "Receptor interacting serine/threonine kinase 1" Q13546 6 3063991-3115187 "Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Inflammatory response, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010302, HPA015257" Supported Supported "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "CAB010302: AB_2178118, HPA015257: AB_1856294" "unprognostic (1.24e-1)" "unprognostic (6.83e-2)" "unprognostic (1.87e-1)" "unprognostic (7.75e-2)" "unprognostic (6.08e-2)" "unprognostic (1.01e-2)" "unprognostic (1.26e-2)" "unprognostic (1.96e-1)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (5.00e-2)" "unprognostic (3.29e-1)" "unprognostic (9.65e-3)" "unprognostic (3.44e-1)" "unprognostic (9.01e-2)" "unprognostic (1.38e-2)" "prognostic favorable (6.71e-4)" 24.5 12.0 6.9 15.7 12.4 10.5 28.0 11.9 11.0 16.4 18.9 9.6 22.9 14.5 16.8 17.7 17.1 13.5 17.9 12.3 7.5 6.8 18.5 36.7 16.7 19.8 11.8 6.6 13.2 19.9 14.4 17.9 24.4 10.2 17.8 16.6 10.9 21.1 18.7 11.4 18.9 24.8 21.3 6.9 19.4 15.8 9.0 9.4 18.6 18.5 15.2 19.2 15.0 20.4 4.1 3.2 6.6 3.9 6.6 7.6 2.1 9.5 6.8 10.3 10.6 22.0 14.1 5.7 15.0 20.4 15.9 18.3 9.2 6.6 8.9 14.5 21.5 16.7 11.0 12.8 12.3 17.4 18.4 6.9 11.5 4.5 6.7 12.4 9.9 14.7 19.0 11.0 14.7 10.7 13.0 13.7 5.5 12.9 5.1 15.3 12.3 6.8 10.8 6.5 11.5 8.5 8.3 7.6 10.0 14.2 19.1 8.9 8.8 9.9 6.2 16.6 21.9 11.4 7.1 16.6 17.4 9.3 6.6 11.1 7.9 10.2 9.5 7.3 5.5 19.2 1.1 3.0 6.4 6.1 3.7 4.9 2.0 4.9 7.6 3.2 4.1 4.1 5.4 6.6 6.6 3.9 2.9 5.7 2.1 6.9 12.4 11.9 11.0 7.5 6.8 11.8 6.6 10.2 9.4 6.0 8.1 8.8 8.6 9.7 3.4 6.9 12.7 21.4 20.5 8.7 11.8 7.3 5.0 8.1 1.6 15.8 13.6 0.0 11.3 5.6 9.8 8.2 10.4 12.3 10.1 4.8 6.3 11.6 5.1 0.4 6.4 11.1 3.3 17.2 15.4 7.2 10.3 10.1 5.6 8.2 21.0 19.4 15.1 0.9 2.5 8.7 10.0 12.5 9.3 12.2 RIPK2 "CARD3, CARDIAK, RICK, RIP2" ENSG00000104312 "Receptor interacting serine/threonine kinase 2" O43353 8 89757747-89791063 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015273, HPA016499" Approved Enhanced Cytosol NA NA Cytosol "HPA015273: AB_1856299, HPA016499: AB_1856300" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (1.67e-1)" "unprognostic (6.20e-2)" "unprognostic (1.43e-3)" "prognostic unfavorable (6.33e-5)" "unprognostic (2.06e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (5.00e-6)" "unprognostic (6.39e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-2)" "unprognostic (5.08e-2)" "unprognostic (1.05e-2)" "prognostic favorable (8.05e-4)" 12.0 5.5 9.3 11.2 7.9 13.6 10.0 3.0 9.3 9.7 7.9 10.6 5.2 3.5 10.9 7.8 8.3 7.0 17.3 11.6 9.2 8.6 7.7 10.4 18.7 10.9 11.8 5.8 8.9 13.2 14.7 7.3 20.8 9.1 10.7 5.6 4.6 10.2 5.8 3.1 10.4 6.9 10.4 16.5 14.2 8.3 5.6 11.5 5.1 8.5 4.9 11.8 15.0 7.6 7.5 6.9 19.4 11.2 3.8 5.5 4.3 10.3 3.6 1.8 2.6 4.5 6.3 3.4 11.5 19.6 6.1 7.9 3.1 5.4 8.0 17.9 6.4 4.9 2.5 4.9 3.8 11.3 5.7 4.9 6.7 1.7 3.1 12.7 2.4 3.3 5.0 3.1 8.7 28.1 6.5 6.4 0.0 3.2 2.6 5.6 2.1 0.0 5.1 1.0 4.7 8.5 1.7 2.6 3.9 14.3 4.6 0.3 2.0 2.7 7.2 5.4 2.5 7.0 3.0 5.7 3.7 3.5 6.3 5.3 5.3 2.4 4.8 9.1 0.2 2.4 8.8 5.7 19.4 3.6 10.6 4.1 7.5 5.5 4.7 6.9 4.3 5.2 5.5 4.5 3.8 11.2 2.3 1.2 4.3 9.3 7.9 3.0 7.4 9.2 8.6 11.8 5.8 9.1 11.5 32.8 17.8 13.4 31.1 51.2 2.4 2.8 5.1 10.7 22.7 3.5 0.0 10.6 5.0 66.4 5.0 9.5 2.3 0.0 53.1 35.2 38.5 46.3 42.7 2.6 39.0 3.2 0.0 5.5 25.3 1.6 7.2 48.6 18.6 50.5 5.2 10.0 41.2 0.0 5.6 6.7 0.1 12.9 22.7 8.1 10.9 42.2 70.0 12.7 6.6 40.4 RIPK3 RIP3 ENSG00000129465 "Receptor interacting serine/threonine kinase 3" Q9Y572 14 24336021-24340045 "Enzymes, Predicted intracellular proteins" "Apoptosis, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.8" "Cell type enhanced" "Detected in many" 7 "Enterocytes: 20.6;Exocrine glandular cells: 30.8;Paneth cells: 17.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 7.6;HDLM-2: 4.3;OE19: 11.3;SK-BR-3: 12.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (1.12e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-2)" "unprognostic (1.11e-1)" "unprognostic (5.26e-3)" "unprognostic (9.58e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-2)" 7.6 1.3 1.8 9.7 2.4 4.3 6.0 0.9 1.6 4.5 13.6 1.8 1.4 10.6 3.7 3.8 9.2 3.2 12.7 2.6 2.7 0.6 3.8 1.3 6.4 7.2 3.9 0.8 1.7 8.4 0.5 0.9 3.7 2.3 3.7 11.8 3.6 7.5 1.7 2.1 5.9 25.8 2.1 3.8 15.1 9.2 1.6 3.6 7.2 8.7 6.1 13.3 4.6 5.6 3.5 5.2 6.3 8.8 3.9 9.1 4.3 0.0 0.0 0.0 0.0 2.9 3.2 0.0 0.7 3.9 0.0 0.0 0.1 7.6 0.1 2.0 0.3 0.0 1.9 0.0 0.1 0.0 4.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.3 1.3 0.0 0.1 0.0 0.0 0.0 0.5 0.0 11.3 0.0 0.0 0.0 1.3 1.4 0.0 0.0 0.0 0.0 12.5 0.0 0.0 2.2 3.3 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 2.6 5.1 6.3 6.3 7.7 6.4 3.5 5.4 6.2 5.2 3.5 2.9 4.0 2.6 3.9 8.8 2.6 9.1 4.3 1.8 2.4 0.9 1.6 2.7 0.6 3.9 0.8 2.3 3.6 3.0 10.8 1.9 1.6 1.3 0.0 0.4 2.5 1.4 1.2 3.5 0.0 0.3 3.3 6.3 0.1 2.9 20.6 0.0 30.8 0.2 1.8 0.6 11.6 0.0 11.0 0.0 5.8 0.0 10.0 0.0 0.0 6.3 3.3 10.8 9.2 0.0 15.3 17.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 1.3 0.2 8.7 6.5 2.3 RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767106 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease mutation, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 9 "naive CD4 T-cell: 1.5;neutrophil: 2.2" "Group enriched" "Detected in many" 17 "granulocytes: 2.2;T-cells: 1.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 15.9;GAMG: 20.8;HaCaT: 23.5;hTCEpi: 15.8;RPTEC TERT1: 14.2;RT4: 15.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030942 Enhanced NA NA "HPA030942: AB_2732462" "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.22e-5)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" 1.0 0.2 0.2 0.8 0.2 0.1 3.3 0.2 0.2 6.7 9.4 0.3 12.0 6.8 1.7 6.5 42.1 4.2 17.1 1.1 0.4 0.2 10.8 17.3 5.4 0.4 0.2 0.1 1.8 14.4 4.7 6.8 2.8 1.1 10.6 1.3 4.8 10.2 14.8 0.2 11.7 11.6 2.0 0.3 0.2 11.2 2.7 0.0 8.1 13.6 12.3 26.6 5.2 11.0 0.0 0.0 2.2 0.1 0.0 1.5 0.2 6.8 4.4 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.1 0.1 11.4 15.9 0.0 6.7 1.4 20.8 23.5 0.3 9.5 0.0 0.0 4.7 0.0 3.3 4.2 0.0 0.0 0.0 0.0 15.8 0.1 2.1 0.0 0.0 7.1 0.0 0.0 0.0 5.0 0.9 0.0 0.4 4.5 13.1 0.0 0.0 1.1 14.2 15.1 2.3 0.1 7.7 7.8 7.1 0.7 4.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 5.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.1 2.2 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.2 0.4 0.2 0.2 0.1 1.1 0.0 26.8 10.8 0.0 26.1 14.1 0.0 1.0 12.7 17.4 14.8 3.5 0.0 7.0 8.3 10.8 0.4 0.0 17.3 0.0 9.0 4.7 0.7 20.1 2.3 16.1 0.9 0.0 21.8 0.0 1.6 1.1 0.0 0.6 6.8 0.0 13.4 0.0 14.2 8.7 0.0 10.0 0.9 0.0 0.3 1.1 0.6 13.2 2.1 0.0 9.8 19.5 RNASEL "PRCA1, RNS4" ENSG00000135828 "Ribonuclease L" Q05823 1 182573634-182589256 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Sertoli cells: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002633, CAB010906" Approved Supported Cytosol NA NA Cytosol "CAB010906: AB_477444, HPA002633: AB_1856314" "unprognostic (3.46e-2)" "unprognostic (9.10e-2)" "unprognostic (7.74e-2)" "unprognostic (1.13e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" "unprognostic (5.43e-2)" "unprognostic (1.99e-1)" "unprognostic (1.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.81e-1)" 8.1 10.8 7.4 9.5 10.9 3.7 8.3 5.7 7.7 12.5 9.3 6.7 8.5 8.0 12.4 11.9 10.0 8.8 8.0 5.8 7.0 5.3 9.9 3.9 8.4 10.1 7.7 3.3 14.0 5.3 13.5 18.0 8.5 10.1 10.5 10.8 13.3 10.5 10.3 4.1 6.3 12.2 9.6 7.4 10.5 8.8 3.5 6.7 13.3 13.3 2.8 11.0 13.9 11.0 5.0 7.2 26.9 13.5 5.0 9.2 4.9 2.3 3.3 1.4 0.5 7.7 13.4 2.6 4.5 5.7 4.7 4.3 1.9 5.2 5.1 8.0 5.1 2.1 4.3 3.4 4.7 1.8 4.1 2.8 6.0 1.2 0.2 3.9 11.1 11.9 9.5 10.8 2.5 0.7 3.0 2.0 7.6 2.1 4.0 4.0 3.4 3.2 4.6 1.1 7.6 0.9 4.8 1.1 2.6 4.9 3.1 0.7 0.2 4.1 5.0 3.9 3.8 5.1 12.4 2.6 2.4 1.9 2.6 2.5 3.5 1.2 0.6 3.8 6.8 3.5 16.8 7.2 24.6 4.9 7.6 6.4 5.0 5.8 5.2 6.0 3.8 9.2 6.7 26.9 5.0 13.5 7.2 4.6 4.9 7.4 10.9 5.7 7.7 7.0 5.3 7.7 3.3 10.1 6.7 6.0 3.4 2.4 2.7 0.9 1.9 1.2 2.5 8.1 5.7 3.5 3.9 3.4 6.6 5.6 0.0 3.6 6.3 0.0 1.6 2.6 3.7 2.7 5.7 1.5 5.5 1.6 2.4 3.1 10.0 0.0 2.6 4.6 0.0 1.0 7.1 9.1 2.6 3.5 6.0 6.1 6.3 19.4 2.1 0.1 0.9 0.9 2.2 6.9 3.0 4.2 ROCK1 p160ROCK ENSG00000067900 "Rho associated coiled-coil containing protein kinase 1" Q13464 18 20946906-21111851 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Early spermatids: 335.7;Late spermatids: 390.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004562, HPA007567, HPA045639" Approved NA NA 240000 "CAB004562: AB_628223, HPA007567: AB_1856393, HPA045639: AB_2679401" "unprognostic (7.86e-2)" "unprognostic (2.86e-2)" "unprognostic (1.22e-1)" "unprognostic (6.63e-2)" "unprognostic (9.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-1)" "unprognostic (8.89e-3)" "prognostic unfavorable (9.93e-4)" "unprognostic (3.85e-2)" "unprognostic (8.93e-3)" "unprognostic (3.04e-2)" "unprognostic (5.47e-2)" "unprognostic (3.19e-1)" "unprognostic (1.28e-1)" 19.3 9.7 9.7 16.3 9.7 40.0 15.1 18.3 11.0 13.9 12.6 7.1 14.4 10.1 16.0 14.9 13.3 14.4 11.7 11.9 10.3 5.6 10.5 9.2 17.0 20.5 10.1 6.0 13.7 9.5 11.2 12.2 11.5 10.3 14.2 9.4 9.5 9.4 9.8 7.9 8.5 11.6 27.7 10.7 17.3 12.0 6.6 12.4 24.8 10.9 9.6 11.2 17.9 21.0 5.4 5.3 17.9 5.0 2.6 5.1 2.0 6.4 4.0 4.0 3.9 7.6 8.2 6.6 9.0 4.4 4.0 4.4 6.7 2.8 8.0 6.5 10.6 2.2 5.3 3.6 5.2 8.2 11.3 4.2 6.4 7.4 2.9 3.9 17.6 10.0 5.9 4.8 6.0 4.9 3.3 6.1 3.2 3.6 8.3 4.7 4.1 8.3 3.8 3.4 4.3 6.8 11.8 4.7 3.1 3.9 6.0 4.7 3.7 7.2 4.9 3.6 3.8 4.8 6.7 10.1 8.2 6.8 7.3 7.3 11.4 5.1 9.2 6.1 7.6 5.0 2.8 5.0 6.3 5.1 3.1 4.1 3.7 3.8 3.9 4.0 5.4 3.7 3.6 17.9 2.6 3.6 5.3 3.2 2.0 9.7 9.7 18.3 11.0 10.3 5.6 10.1 6.0 10.3 12.4 89.3 78.4 61.5 52.6 41.1 96.1 123.9 25.5 57.6 86.4 31.4 123.7 47.6 13.3 52.8 335.7 72.9 30.7 0.0 33.3 52.8 65.1 50.5 69.5 41.2 54.5 57.2 95.0 46.1 128.2 390.9 90.3 132.9 62.4 85.6 37.7 47.5 51.9 60.4 130.4 14.9 135.4 168.1 157.5 68.9 76.9 32.0 35.9 96.4 35.1 57.6 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179761-11348330 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 3700000 Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 26.9 7.8 14.6 9.5 21.9 4.4 21.4 26.1 26.4 16.6 16.5 5.6 8.6 12.3 22.4 11.0 12.4 13.2 11.9 12.3 13.4 7.6 11.4 12.3 16.7 6.8 7.2 16.7 15.1 8.6 12.9 14.8 18.4 10.3 14.4 20.3 5.6 10.3 14.4 28.0 8.7 13.8 42.9 7.1 12.6 10.7 5.8 9.6 5.9 10.5 5.1 6.2 22.1 20.8 2.5 3.0 3.6 2.2 3.5 3.3 0.9 6.6 16.2 13.4 13.1 24.3 17.1 8.6 15.8 14.8 10.3 10.9 15.3 14.6 8.4 9.4 24.9 12.5 7.4 9.7 9.1 16.3 11.9 5.8 16.7 27.9 30.5 8.7 9.3 4.8 13.3 5.8 12.7 9.1 8.4 16.4 4.6 14.5 3.4 15.3 5.6 6.8 4.8 7.4 14.1 10.0 8.2 29.5 2.7 5.6 18.9 6.3 6.8 31.0 10.8 10.8 10.6 4.4 5.2 22.3 21.3 15.4 8.4 13.8 2.7 3.3 7.5 9.2 11.0 29.6 3.6 1.8 1.7 2.7 2.2 3.3 1.6 2.2 1.8 1.3 2.5 1.9 2.1 3.0 3.5 1.7 3.0 1.8 0.9 14.6 21.9 26.1 26.4 13.4 7.6 7.2 16.7 10.3 9.6 107.2 64.4 9.3 35.3 35.4 33.2 94.7 35.7 41.5 86.4 21.0 55.0 22.5 1.7 25.4 6.5 88.7 62.6 0.0 34.0 15.9 43.2 45.6 26.7 37.6 16.5 76.3 20.4 58.9 19.8 3.5 40.6 24.0 21.9 8.2 82.3 34.2 30.5 38.6 73.9 13.6 42.5 129.4 101.5 21.4 17.7 24.3 26.3 11.4 40.0 38.2 ROR1 NTRKR1 ENSG00000185483 "Receptor tyrosine kinase like orphan receptor 1" Q01973 1 63774022-64181498 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase" "Deafness, Disease mutation, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 31.2" "Cell type enhanced" "Detected in many" 10 "Alveolar cells type 1: 47.6;Intestinal endocrine cells: 20.6;Leydig cells: 25.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "cerebellum: 13.0" "Group enriched" "Detected in some" 5 "NK-cell: 3.3;plasmacytoid DC: 1.1" "Group enriched" "Detected in many" 5 "dendritic cells: 1.1;NK-cells: 3.3" "Cell line enhanced" "Detected in many" "ASC diff: 19.8;ASC TERT1: 24.8;CACO-2: 16.9;HHSteC: 18.8;HSkMC: 20.3;NTERA-2: 20.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057016 Approved Microtubules "Intracellular and membrane" NA NA 2800000 Microtubules "HPA057016: " "unprognostic (5.15e-2)" "unprognostic (1.19e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-1)" "unprognostic (7.11e-3)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "unprognostic (3.84e-1)" "unprognostic (3.20e-2)" "unprognostic (2.02e-2)" "unprognostic (3.64e-3)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.87e-2)" "unprognostic (5.15e-2)" 5.5 1.7 1.3 3.5 2.7 0.4 3.4 13.0 2.8 16.7 8.8 2.2 4.4 2.0 14.2 5.0 4.9 5.5 10.7 10.6 1.3 1.1 3.6 0.8 9.7 1.1 1.0 2.4 8.3 9.8 31.2 3.6 2.9 3.0 10.9 3.9 7.9 2.8 6.3 2.1 4.5 4.1 17.8 1.1 3.1 9.2 2.7 0.9 1.8 1.5 4.6 2.1 10.2 8.8 0.4 1.1 0.1 0.1 3.3 0.1 0.0 7.1 5.6 2.8 0.4 19.8 24.8 1.9 1.4 3.9 0.8 2.0 16.9 2.3 0.1 3.2 3.3 1.4 1.5 0.0 1.3 0.5 0.0 1.8 0.0 0.7 0.2 18.8 0.0 0.0 20.3 5.2 10.4 12.2 4.0 0.3 0.2 0.0 0.1 5.2 0.1 0.1 0.0 20.6 5.2 2.8 0.1 0.1 4.4 4.1 0.1 1.6 6.6 0.4 0.1 2.9 10.0 0.0 0.0 3.9 1.6 2.9 11.0 2.9 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.1 3.3 0.1 1.1 0.0 0.0 1.3 2.7 13.0 2.8 1.3 1.1 1.0 2.4 3.0 0.9 47.6 8.0 0.0 1.8 3.4 1.7 8.5 2.5 1.4 2.3 1.8 0.0 0.2 0.0 5.3 7.8 1.3 0.0 0.0 13.4 0.7 7.6 1.5 0.0 0.0 5.8 0.0 20.6 1.3 0.0 4.7 25.6 0.0 3.3 0.0 2.3 4.9 10.7 0.0 13.8 2.8 0.0 6.5 12.0 0.7 1.2 4.0 0.2 0.0 2.6 0.9 ROR2 "BDB, BDB1, NTRKR2" ENSG00000169071 "Receptor tyrosine kinase like orphan receptor 2" Q01974 9 91563091-91950162 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease mutation, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 4 "Basal glandular cells: 9.7;Fibroblasts: 9.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 6 "pons and medulla: 6.6" "Cell type enriched" "Detected in single" 6 "MAIT T-cell: 3.9" "Lineage enriched" "Detected in single" 6 "T-cells: 3.9" "Cell line enhanced" "Detected in many" "AF22: 12.3;HHSteC: 32.4;HSkMC: 26.9;U-266/70: 18.7;U-266/84: 12.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "cerebellum: 13.5" HPA021868 Uncertain NA NA "HPA021868: AB_1856406" "unprognostic (9.38e-3)" "unprognostic (4.69e-1)" "unprognostic (2.26e-1)" "unprognostic (8.48e-3)" "unprognostic (1.23e-1)" "unprognostic (2.38e-1)" "unprognostic (2.06e-1)" "unprognostic (1.31e-1)" "unprognostic (8.03e-2)" "unprognostic (2.03e-1)" "unprognostic (5.76e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (9.86e-7)" "unprognostic (2.16e-3)" "unprognostic (9.13e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (1.25e-2)" 4.4 4.3 0.7 5.3 1.1 0.0 3.6 0.2 0.8 23.4 20.7 2.9 11.1 1.9 29.1 9.1 8.0 8.1 18.7 8.5 1.0 0.9 2.0 0.5 4.2 0.7 0.3 0.0 19.1 3.1 20.3 1.3 7.1 6.6 20.3 2.1 11.0 1.2 13.1 1.1 2.9 6.2 30.0 0.3 4.7 10.5 5.2 0.3 2.6 7.9 1.9 3.3 23.7 18.1 0.6 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.1 12.3 0.0 2.7 0.2 3.5 0.2 3.2 2.1 3.9 0.0 0.0 0.0 0.0 0.6 1.9 0.1 2.5 0.0 0.9 0.0 2.0 0.0 9.4 0.0 32.4 0.0 0.0 26.9 0.0 2.8 0.0 0.0 0.0 0.1 6.8 0.0 0.0 0.2 0.0 1.7 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.6 0.2 0.0 0.0 2.7 7.3 0.1 0.0 0.0 2.4 1.0 0.0 18.7 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.2 0.8 1.0 0.9 0.3 0.0 6.6 0.3 0.0 0.0 0.0 9.7 2.7 1.9 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 3.5 1.1 0.0 0.0 1.3 0.1 9.1 8.3 1.1 0.0 0.7 0.0 2.9 0.6 0.0 6.0 5.5 0.0 5.0 2.8 2.8 6.8 0.8 0.0 8.5 0.0 0.2 6.5 3.9 1.0 6.8 1.9 0.3 0.0 0.8 4.4 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117288300-117425855 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 38.6;lung: 20.2" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 14.9;Alveolar cells type 2: 56.7" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Group enriched" "Detected in some" 10 "cerebral cortex: 7.4;olfactory region: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "GAMG: 16.3;HSkMC: 8.7;hTCEpi: 18.1;LHCN-M2: 12.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA Vesicles "HPA049098: AB_2680628, HPA072424: AB_2686519" "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.3 0.2 0.2 0.0 0.4 0.0 0.2 0.2 7.4 0.2 0.4 0.0 7.9 0.0 0.2 38.6 0.2 0.2 0.0 0.2 0.2 0.2 0.4 0.2 20.2 0.0 0.2 2.5 0.2 0.2 0.0 0.3 0.7 0.0 0.2 0.3 0.0 0.2 2.3 0.2 0.7 0.3 0.0 0.2 0.2 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 8.7 18.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.6 0.0 2.2 1.4 0.1 1.7 0.0 0.0 0.0 1.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 7.4 0.2 0.2 0.2 2.5 0.0 0.0 14.9 56.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 RPS6KA1 "HU-1, p90Rsk, RSK, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 45.2" "Cell type enhanced" "Detected in many" 6 "Enterocytes: 85.8;monocytes: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.9;U-937: 32.2" "Region enriched" "Detected in all" 5 "cerebellum: 60.4" "Low region specificity" "Detected in all" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "CAB003852: AB_289590, HPA007981: AB_1079850" "unprognostic (1.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.61e-3)" "prognostic favorable (7.20e-7)" "unprognostic (7.35e-2)" "unprognostic (3.69e-1)" "unprognostic (6.93e-3)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.84e-4)" "prognostic favorable (4.58e-4)" "unprognostic (4.77e-2)" "unprognostic (7.61e-2)" "prognostic favorable (8.33e-4)" 11.0 8.2 6.3 24.2 9.7 15.8 5.0 14.4 6.3 4.9 23.2 11.1 4.4 24.5 2.1 3.6 8.9 6.0 8.0 3.4 5.3 5.1 13.6 5.4 26.1 32.7 10.3 3.5 2.1 10.1 10.0 7.4 3.3 8.6 8.6 15.8 3.6 19.0 5.5 1.1 9.0 45.2 2.8 7.9 27.0 9.7 2.7 9.0 15.9 13.9 4.9 17.3 6.2 4.5 5.0 22.0 40.1 18.0 7.9 8.3 17.1 9.9 3.5 2.8 3.7 0.1 0.0 3.8 0.8 1.6 4.2 4.1 4.0 8.2 18.5 4.6 0.5 5.1 11.7 6.4 22.9 3.0 15.3 4.1 20.3 8.6 7.1 1.3 23.9 29.9 0.7 8.4 3.9 7.0 1.9 1.8 7.4 3.4 6.7 0.2 5.5 0.8 23.6 7.3 19.3 11.1 12.8 3.6 8.1 12.1 2.7 4.1 1.6 7.0 6.6 3.2 3.1 4.2 20.6 1.2 0.2 5.4 0.7 3.3 4.2 4.9 10.1 2.5 32.2 4.1 9.6 18.0 40.1 8.3 16.4 6.9 4.9 6.1 7.3 22.0 5.0 3.9 5.5 34.5 7.9 17.3 8.6 6.0 17.1 6.3 9.7 14.4 6.3 5.3 5.1 10.3 3.5 8.6 9.0 14.9 23.5 13.7 7.4 16.6 1.3 1.2 10.2 10.7 5.7 8.7 3.9 1.2 6.6 15.5 1.8 4.2 85.8 0.0 16.3 14.5 1.9 13.9 32.2 3.8 43.9 0.0 15.6 12.3 57.1 0.5 0.0 36.8 1.7 68.5 34.3 0.4 21.8 41.9 0.0 13.6 1.7 6.5 2.1 1.1 2.7 10.2 3.4 41.5 32.9 6.8 RPS6KA2 "HU-2, RSK, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Horizontal cells: 271.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 4 "eosinophil: 17.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 17.5" "Cell line enhanced" "Detected in many" "ASC diff: 48.4;ASC TERT1: 35.5;HHSteC: 35.9;HSkMC: 31.9;hTERT-HME1: 38.6;hTERT-RPE1: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: AB_2679203, HPA054237: AB_2682425" "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favorable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 15.4 6.5 26.8 5.3 35.5 6.9 12.7 12.1 21.5 13.5 7.1 20.3 11.5 4.3 18.3 5.2 14.0 11.9 12.5 40.9 25.0 18.3 9.9 3.3 24.6 10.6 22.4 18.4 20.9 30.2 32.6 18.0 12.1 22.7 10.6 7.4 11.1 9.0 10.5 14.4 7.5 7.2 15.8 37.2 16.5 10.4 5.1 25.7 0.8 24.8 3.5 4.9 15.5 10.2 0.4 3.9 17.5 1.6 3.3 0.6 0.2 1.9 0.0 3.9 5.7 48.4 35.5 0.0 4.1 8.1 2.3 3.2 0.0 1.2 0.2 1.3 14.6 1.8 1.7 2.0 9.0 2.1 0.8 0.5 0.0 8.5 0.1 35.9 0.1 1.6 31.9 6.5 12.5 38.6 70.4 12.6 4.1 0.0 0.0 9.5 0.4 0.1 0.4 1.0 1.9 2.3 0.6 2.0 5.7 2.4 2.1 2.1 15.2 1.4 3.9 5.3 1.0 0.1 3.0 4.6 8.3 0.8 22.8 1.2 1.1 1.7 0.5 5.5 0.2 7.8 0.1 0.5 17.5 0.5 0.7 0.2 0.3 0.5 0.2 0.7 0.4 0.6 0.3 0.4 3.3 1.6 3.9 0.4 0.2 26.8 35.5 12.1 21.5 25.0 18.3 22.4 18.4 22.7 25.7 20.8 34.5 0.0 4.1 4.1 34.9 54.9 22.9 2.7 13.6 34.9 7.9 0.1 10.0 12.8 12.0 47.2 0.5 0.0 20.9 0.2 8.0 9.4 2.3 11.6 7.2 271.7 5.2 38.6 5.0 48.4 4.9 4.7 18.6 3.6 5.5 8.3 22.7 1.4 4.2 4.4 15.4 12.9 6.9 3.2 1.1 3.0 0.2 1.3 1.2 5.8 RPS6KA3 "CLS, HU-3, MRX19, RSK, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Supported Nucleoplasm,Nucleoli,Cytosol No No Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" 19.7 12.5 9.9 23.0 12.5 8.2 16.5 15.2 12.1 11.4 23.2 4.4 22.1 13.7 12.4 10.1 13.6 12.7 15.7 21.3 9.7 8.8 14.1 25.8 21.6 34.0 9.9 10.0 12.7 14.0 36.6 9.8 11.0 10.2 14.5 18.8 7.7 14.3 11.3 45.2 11.7 23.7 16.1 11.7 25.8 11.8 4.8 9.7 29.4 13.5 15.0 18.2 20.3 19.0 4.2 8.6 12.5 6.9 8.3 11.3 2.7 12.9 22.7 8.6 4.4 8.4 14.8 2.6 11.2 17.1 8.4 11.6 25.7 16.7 8.5 3.9 11.8 12.3 9.2 9.8 9.5 15.7 7.1 7.8 10.0 14.3 69.0 8.6 19.5 10.4 9.4 7.6 13.2 16.7 7.4 30.4 9.0 6.6 24.4 8.8 6.1 12.6 6.0 6.2 16.9 13.7 6.7 18.2 9.8 7.3 10.9 4.0 3.9 15.1 4.6 16.4 11.2 0.0 5.8 16.9 9.2 6.4 29.1 6.3 19.5 11.9 9.5 17.4 9.7 21.7 12.5 4.7 9.5 6.3 6.9 11.3 2.9 7.3 6.9 7.0 4.2 5.0 6.0 7.5 8.3 6.9 8.6 3.5 2.7 9.9 12.5 15.2 12.1 9.7 8.8 9.9 10.0 10.2 9.7 41.7 68.2 18.2 31.8 48.3 33.6 19.4 38.2 21.4 51.2 15.7 21.6 3.3 3.3 23.3 0.1 48.1 43.4 0.0 26.0 5.7 28.8 47.0 42.8 61.1 20.6 12.7 24.0 29.4 46.1 1.1 12.0 60.4 35.4 20.8 53.4 26.6 30.0 46.0 19.8 23.7 8.7 19.4 35.0 3.3 7.7 48.6 3.0 56.7 46.1 54.2 RPS6KA4 "MSK2, RSK-B" ENSG00000162302 "Ribosomal protein S6 kinase A4" O75676 11 64359148-64372215 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Cytotrophoblasts: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "plasmacytoid DC: 12.6" "Lineage enriched" "Detected in many" 4 "dendritic cells: 12.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008649, HPA023225" Approved Supported Nucleoplasm,Cytosol No No Nucleoplasm Cytosol "CAB008649: AB_1619460, HPA023225: AB_1854144" "unprognostic (2.30e-1)" "unprognostic (7.05e-2)" "unprognostic (2.03e-1)" "unprognostic (4.07e-2)" "unprognostic (2.40e-1)" "unprognostic (7.47e-2)" "prognostic unfavorable (8.17e-4)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.45e-1)" "unprognostic (9.03e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-3)" "unprognostic (1.98e-2)" "unprognostic (3.93e-3)" "unprognostic (5.25e-2)" "unprognostic (1.09e-1)" "unprognostic (2.85e-1)" 14.9 9.1 13.3 15.7 17.1 13.2 7.6 37.6 22.7 7.7 12.4 13.1 5.8 14.0 11.0 6.9 18.5 8.1 10.5 7.8 10.9 10.1 8.7 9.6 10.9 15.0 16.7 9.9 6.5 9.2 5.7 4.7 16.6 9.8 8.3 8.4 10.0 10.9 8.9 16.3 17.3 15.4 9.8 11.5 22.2 18.3 3.3 13.5 7.6 6.7 16.7 16.4 9.7 8.8 0.5 12.6 1.4 3.0 0.3 1.0 2.1 28.1 15.8 2.3 5.7 5.1 4.8 32.6 15.0 7.9 11.8 5.8 15.6 14.8 2.9 17.5 8.6 15.0 26.1 2.7 12.2 5.8 8.9 5.3 6.6 13.5 7.9 5.1 6.7 12.4 4.7 11.5 10.0 8.2 4.2 7.1 5.4 2.7 4.1 5.9 25.8 6.0 10.5 2.5 10.9 33.3 11.8 9.4 9.4 8.1 13.0 3.4 2.7 15.5 9.5 13.0 3.4 11.1 8.3 14.1 16.1 20.2 29.0 13.3 4.9 3.8 2.9 10.6 7.7 8.1 1.1 3.0 1.4 0.9 2.4 1.0 0.5 0.7 0.7 2.7 0.4 0.4 0.4 0.2 0.3 1.4 12.6 0.6 2.1 13.3 17.1 37.6 22.7 10.9 10.1 16.7 9.9 9.8 13.5 3.0 4.0 5.7 4.6 10.8 6.3 11.8 5.1 0.0 1.2 3.5 3.9 60.8 5.0 13.7 0.2 7.4 17.0 0.0 21.8 31.5 9.1 7.1 19.5 6.4 26.9 7.9 8.1 11.6 29.2 0.7 10.3 15.3 8.5 12.6 11.6 3.1 40.7 10.7 6.3 7.3 2.0 0.0 9.2 0.7 7.2 9.4 39.0 8.7 13.9 8.5 RPS6KA5 "MSK1, RLPK" ENSG00000100784 "Ribosomal protein S6 kinase A5" O75582 14 90847862-91060636 "Enzymes, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "granulocytes: 86.9;Syncytiotrophoblasts: 93.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 30.1;SK-BR-3: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001274, HPA001780, CAB025458" Approved Enhanced Nucleoplasm NA NA Nucleoplasm "CAB025458: , HPA001274: AB_1079417, HPA001780: AB_2666432" "unprognostic (3.05e-2)" "unprognostic (2.19e-3)" "unprognostic (4.27e-4)" "unprognostic (1.98e-3)" "unprognostic (4.79e-2)" "unprognostic (4.20e-4)" "unprognostic (3.70e-2)" "unprognostic (5.80e-4)" "unprognostic (6.70e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "unprognostic (1.38e-4)" "unprognostic (5.73e-3)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (1.75e-1)" 4.9 2.4 8.3 13.0 21.6 5.8 16.3 32.9 12.2 7.0 11.0 12.0 4.2 9.3 11.8 2.6 11.9 8.9 6.7 6.1 9.0 7.9 4.5 4.1 6.1 7.3 12.8 9.7 10.2 4.9 12.0 6.9 14.9 11.0 8.0 11.7 2.8 8.7 9.9 14.3 6.6 9.8 19.4 17.1 7.4 9.8 5.2 13.7 4.8 8.6 7.8 7.7 11.6 7.3 5.8 2.5 20.0 3.2 8.4 7.1 2.2 1.2 1.7 2.0 1.3 0.0 0.4 8.7 0.7 1.1 2.3 3.4 0.9 2.3 5.9 2.5 2.2 1.6 3.8 1.7 1.7 4.8 0.9 3.1 5.9 1.7 0.2 0.0 5.8 30.1 0.5 3.6 1.4 1.1 0.5 2.5 4.1 0.6 6.7 2.3 2.5 1.8 2.9 0.6 3.7 2.7 3.2 9.6 3.0 2.5 2.2 10.1 3.2 2.5 15.1 8.5 1.8 2.9 1.9 0.5 0.7 1.3 0.6 2.9 2.9 2.8 5.1 1.4 4.3 9.5 10.5 2.7 7.8 3.6 2.1 5.9 4.4 4.8 3.5 2.5 5.8 5.6 3.0 20.0 8.4 3.2 1.0 7.1 2.2 8.3 21.6 32.9 12.2 9.0 7.9 12.8 9.7 11.0 13.7 17.9 27.4 40.7 37.9 35.8 29.4 14.1 12.7 37.5 29.6 7.0 15.7 31.0 0.0 8.9 5.5 19.6 27.6 0.0 4.6 4.7 13.2 25.2 86.9 6.8 6.4 25.4 15.6 14.1 16.1 2.1 13.0 16.9 18.6 2.8 17.9 12.9 3.0 11.5 11.0 2.8 29.2 12.9 27.6 13.1 23.7 40.5 93.5 39.5 18.8 42.3 RPS6KA6 RSK4 ENSG00000072133 "Ribosomal protein S6 kinase A6" Q9UK32 X 84058346-84187907 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ductus deferens: 20.7" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 19.9;Collecting duct cells: 17.4;Cone photoreceptor cells: 23.6;Intestinal endocrine cells: 24.0;Rod photoreceptor cells: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 11.0;PC-3: 11.9;RH-30: 14.6;SH-SY5Y: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002852, HPA003904" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Nucleoplasm, Mitochondria" Nucleoli "HPA002852: AB_1079854, HPA003904: AB_1079853" "unprognostic (1.17e-1)" "unprognostic (1.02e-2)" "unprognostic (3.44e-1)" "unprognostic (4.93e-4)" "unprognostic (1.71e-1)" "unprognostic (3.04e-3)" "unprognostic (2.09e-2)" "unprognostic (2.50e-1)" "unprognostic (2.86e-1)" "unprognostic (4.88e-2)" "unprognostic (3.38e-3)" "unprognostic (2.88e-1)" "unprognostic (2.12e-9)" "unprognostic (4.44e-3)" "unprognostic (1.30e-2)" "unprognostic (2.34e-2)" "unprognostic (8.49e-3)" 0.7 2.9 5.9 1.0 12.2 0.0 2.3 4.7 5.1 3.1 4.5 1.1 20.7 1.7 2.7 4.0 1.5 4.0 1.9 1.2 5.1 2.9 9.2 0.9 0.8 0.2 1.5 3.3 4.9 3.4 13.5 9.1 0.5 4.4 4.3 3.7 1.5 3.0 15.0 1.4 2.3 2.0 1.7 1.0 0.6 2.4 2.6 2.7 0.8 14.5 0.9 0.6 3.3 2.3 1.2 0.8 2.4 0.5 0.7 2.8 0.1 0.0 3.7 3.6 0.0 3.4 3.4 0.0 7.7 4.1 3.4 2.9 2.8 3.0 0.0 0.0 4.1 0.0 0.1 9.1 6.1 8.1 0.0 4.6 0.0 0.1 0.0 3.1 0.0 0.0 1.9 0.0 0.0 3.8 3.8 0.8 0.0 0.0 0.2 2.7 0.0 1.3 0.1 11.0 0.0 11.9 0.0 14.6 0.0 0.6 8.5 0.0 11.7 0.0 4.2 0.0 5.2 2.0 0.0 0.0 0.1 4.4 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 2.4 0.4 0.5 0.5 0.3 0.4 1.2 0.4 0.7 0.8 0.6 0.4 0.4 1.1 0.7 0.5 0.4 2.8 0.1 5.9 12.2 4.7 5.1 5.1 2.9 1.5 3.3 4.4 2.7 8.9 2.4 2.0 4.4 0.2 19.9 2.0 12.7 6.7 3.4 17.4 23.6 2.1 1.7 0.4 0.4 0.6 3.4 0.0 1.1 0.6 0.3 7.4 0.0 1.5 0.2 1.6 24.0 1.3 0.0 0.0 4.0 0.0 0.0 0.0 5.0 2.8 1.3 2.9 5.6 3.3 18.2 0.0 0.6 3.7 6.3 0.4 1.9 0.0 5.3 4.2 RPS6KB1 "p70(S6K)-alpha, PS6K, S6K1, STK14A" ENSG00000108443 "Ribosomal protein S6 kinase B1" P23443 17 59893046-59950564 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "MCF7: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003838, CAB018346, HPA039442" Approved Supported Nucleoplasm NA NA Nucleoplasm "CAB003838: AB_562325, CAB018346: AB_632156, HPA039442: AB_2676510" "unprognostic (2.25e-1)" "unprognostic (4.52e-2)" "unprognostic (1.91e-3)" "unprognostic (1.35e-2)" "unprognostic (9.81e-2)" "unprognostic (1.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.70e-1)" "unprognostic (5.86e-2)" "unprognostic (1.66e-1)" "unprognostic (3.67e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.09e-7)" "unprognostic (3.45e-1)" "unprognostic (2.09e-1)" "unprognostic (3.98e-2)" "unprognostic (1.52e-3)" 18.4 18.3 16.6 23.2 19.5 20.5 18.4 25.7 24.2 18.1 18.2 13.1 18.4 13.1 19.6 16.5 25.4 14.5 14.9 14.2 15.7 12.6 13.5 20.0 14.8 17.3 20.3 17.5 21.6 22.3 24.5 18.9 20.3 17.6 16.7 15.0 10.1 17.3 21.5 50.3 15.8 14.1 19.3 19.8 17.6 17.5 10.7 20.0 17.8 16.8 18.4 22.0 18.5 20.8 8.9 12.8 25.9 11.1 9.4 13.5 8.3 10.9 10.6 9.1 8.6 6.3 9.2 6.9 10.1 9.4 8.9 10.0 8.7 5.5 13.2 12.6 8.4 10.7 5.7 12.0 9.1 14.4 7.3 13.4 9.0 6.9 9.9 9.3 13.9 9.1 9.4 7.0 10.3 7.6 7.4 11.6 8.5 11.9 8.5 6.6 76.1 16.5 5.9 6.1 9.6 8.2 9.8 15.4 12.3 7.4 8.1 6.6 8.0 8.5 5.0 5.4 11.0 9.8 7.7 10.0 8.7 14.5 7.0 13.4 15.4 13.0 14.9 6.6 8.6 6.9 25.9 10.1 9.0 11.4 10.2 13.5 8.9 10.5 13.0 12.8 8.6 12.3 12.9 10.0 9.4 11.1 8.0 9.5 8.3 16.6 19.5 25.7 24.2 15.7 12.6 20.3 17.5 17.6 20.0 20.8 32.2 20.1 17.7 29.3 16.3 13.7 17.8 25.4 38.7 3.5 17.7 20.8 3.3 10.9 2.6 18.8 10.1 0.0 14.1 15.1 21.8 21.4 22.0 12.4 10.6 17.5 12.7 11.1 14.8 2.1 14.7 18.0 10.1 16.2 16.1 11.9 13.7 10.5 17.0 7.2 18.5 25.8 22.8 11.1 13.1 28.0 25.5 20.3 13.4 24.3 RPS6KB2 "KLS, P70-BETA, p70S6Kb, STK14B" ENSG00000175634 "Ribosomal protein S6 kinase B2" Q9UBS0 11 67428460-67435408 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010010, CAB019404" Approved Supported Cytosol NA NA Cytosol "CAB019404: AB_331355, HPA010010: AB_1856469" "unprognostic (1.38e-1)" "unprognostic (2.36e-3)" "unprognostic (8.50e-2)" "unprognostic (2.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.41e-1)" "unprognostic (9.01e-3)" "unprognostic (5.10e-2)" "unprognostic (1.22e-1)" "unprognostic (9.49e-3)" "unprognostic (7.66e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.03e-7)" "unprognostic (1.28e-2)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (2.66e-1)" 8.7 14.1 8.5 12.8 9.2 18.0 11.2 12.9 11.5 13.1 13.0 12.5 12.3 19.8 10.2 10.1 36.1 11.0 10.7 10.7 8.8 4.2 11.3 27.8 10.7 12.0 11.4 8.7 9.5 18.7 9.6 11.7 13.8 8.7 17.2 9.9 11.7 18.1 15.8 25.0 41.4 17.7 8.8 7.6 18.6 17.1 7.5 8.8 21.8 11.4 28.6 21.8 10.1 15.6 15.7 27.1 16.4 28.3 17.8 20.7 20.2 21.3 16.2 8.9 15.0 4.1 8.0 11.7 10.3 13.0 19.4 13.5 25.3 14.4 7.9 18.0 10.1 12.1 16.0 10.0 15.8 7.8 13.6 26.6 12.7 20.7 20.6 14.0 16.1 15.7 10.1 16.6 10.2 10.5 4.9 14.4 21.0 20.4 21.2 9.7 32.8 24.7 25.3 9.5 31.4 20.9 18.3 12.3 37.5 9.0 12.3 13.4 14.4 10.7 29.7 22.1 5.4 34.9 13.4 6.0 10.1 10.8 24.5 11.5 19.0 15.6 12.7 16.6 10.1 12.7 9.7 22.6 16.4 15.7 25.2 15.9 15.7 14.9 15.3 27.1 14.3 10.9 11.9 15.1 17.8 28.3 18.7 20.7 20.2 8.5 9.2 12.9 11.5 8.8 4.2 11.4 8.7 8.7 8.8 8.9 18.6 37.3 23.0 44.3 24.7 1.1 40.8 4.0 9.1 7.0 9.8 63.1 36.5 40.3 10.4 15.8 75.3 23.3 56.9 74.1 22.2 38.7 27.6 48.6 53.5 31.8 44.4 16.0 37.6 22.0 18.7 27.9 18.6 55.1 53.9 19.0 40.6 63.3 16.3 27.7 26.0 19.4 22.7 13.1 13.8 55.7 86.6 44.9 49.3 30.7 RPS6KC1 humS6PKh1 ENSG00000136643 "Ribosomal protein S6 kinase C1" Q96S38 1 213051233-213274773 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Late spermatids: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026531, HPA031565" Approved Supported Endosomes,Lysosomes NA NA "Endosomes, Lysosomes" "HPA026531: AB_10601497, HPA031565: AB_2673935" "unprognostic (3.90e-2)" "unprognostic (5.90e-2)" "unprognostic (3.22e-1)" "unprognostic (4.88e-2)" "unprognostic (2.42e-1)" "unprognostic (9.81e-2)" "unprognostic (1.32e-2)" "unprognostic (1.64e-1)" "unprognostic (4.10e-2)" "unprognostic (3.34e-1)" "unprognostic (4.18e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (8.10e-2)" "unprognostic (5.48e-2)" "unprognostic (2.98e-2)" "unprognostic (4.44e-2)" 12.0 14.1 15.6 10.0 19.4 6.4 17.1 13.5 19.4 14.1 13.1 12.6 8.8 9.2 15.9 8.4 10.3 11.8 11.6 9.4 17.3 15.6 9.8 10.8 13.6 7.5 17.8 16.8 14.4 13.5 19.9 16.7 12.3 15.3 17.6 10.1 7.3 8.9 17.7 14.1 6.7 8.7 18.5 22.3 11.0 12.5 26.5 13.2 6.8 10.4 6.1 7.8 14.6 16.0 2.5 8.7 13.7 6.8 4.0 3.3 2.2 7.3 6.4 10.5 11.3 10.5 15.6 9.2 9.7 14.3 15.1 17.4 5.2 8.2 4.7 6.6 14.6 9.9 6.1 12.7 7.9 11.5 9.8 4.7 12.6 7.5 7.1 9.7 7.9 15.0 10.2 6.9 13.2 7.2 12.7 12.5 4.6 16.2 7.3 15.4 4.0 3.3 2.6 15.2 6.6 7.2 3.9 9.9 4.5 6.9 7.4 6.1 15.9 10.5 8.3 13.9 18.7 11.9 3.3 11.6 10.3 9.5 11.8 6.3 4.3 8.2 3.6 4.4 3.1 10.5 13.7 4.6 3.3 2.8 6.8 2.3 2.5 2.3 2.4 8.7 1.9 1.5 3.3 0.5 4.0 6.3 1.0 1.6 2.2 15.6 19.4 13.5 19.0 17.3 15.6 17.8 16.8 15.3 13.2 8.9 4.3 1.4 2.2 2.6 17.1 8.9 7.6 4.0 4.5 0.0 13.7 2.6 0.0 4.4 25.9 6.5 4.0 0.0 6.8 3.3 6.9 4.5 7.0 8.1 6.1 19.1 3.5 10.4 8.6 33.0 10.3 9.8 6.8 6.4 3.2 6.6 5.4 2.8 7.1 4.6 18.9 12.9 5.1 13.4 17.2 3.9 3.2 5.1 3.7 2.6 RPS6KL1 MGC11287 ENSG00000198208 "Ribosomal protein S6 kinase like 1" Q9Y6S9 14 74903954-74923396 "Enzymes, Predicted intracellular proteins" "Kinase, Ribonucleoprotein, Ribosomal protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.1" "Cell type enhanced" "Detected in many" 10 "Bipolar cells: 67.9;Cone photoreceptor cells: 78.5;Horizontal cells: 38.1;Rod photoreceptor cells: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.0;naive CD4 T-cell: 1.9;naive CD8 T-cell: 2.0;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 26 "B-cells: 2.0;dendritic cells: 5.4;T-cells: 2.0" "Cell line enhanced" "Detected in many" "HMC-1: 13.0;SCLC-21H: 24.9;SK-BR-3: 14.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027451, HPA027794" Approved Approved Nucleoplasm NA NA Nucleoplasm "HPA027451: AB_10599304, HPA027794: AB_10602098" "unprognostic (2.71e-2)" "unprognostic (9.33e-3)" "unprognostic (3.36e-1)" "unprognostic (1.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.44e-2)" "unprognostic (7.49e-4)" "unprognostic (2.06e-1)" "unprognostic (1.54e-1)" "unprognostic (4.09e-3)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "unprognostic (1.33e-2)" "unprognostic (1.14e-1)" "unprognostic (7.03e-2)" "unprognostic (7.52e-2)" 4.2 7.5 14.7 2.3 13.6 4.2 5.7 18.2 29.1 2.1 4.8 9.0 2.2 3.8 5.1 8.8 5.3 2.5 3.7 10.2 14.3 13.7 2.3 2.1 2.5 2.5 11.1 15.3 1.5 6.7 4.0 10.6 1.4 8.4 2.8 5.6 5.9 3.2 5.4 12.7 1.2 2.8 6.9 8.8 1.7 2.0 11.4 6.8 0.0 3.8 1.2 2.5 1.9 0.8 2.0 5.4 0.1 0.0 0.0 2.0 0.1 2.3 0.3 1.0 3.8 0.1 0.0 4.5 0.4 0.2 1.8 0.5 5.6 1.6 0.0 3.5 0.7 0.5 0.3 1.8 0.3 2.4 0.0 0.8 1.9 0.8 4.2 4.7 2.2 13.0 0.3 3.2 2.0 0.0 0.0 5.9 0.0 2.7 0.7 0.1 7.6 0.0 0.8 0.8 0.7 3.7 1.8 0.0 7.2 1.8 0.0 24.9 3.0 0.3 14.4 2.4 2.0 1.4 1.5 4.0 0.1 0.2 3.1 0.0 10.1 5.3 5.3 1.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.2 2.0 0.4 0.1 0.0 0.4 1.9 2.0 0.1 0.0 0.0 5.4 0.0 0.1 14.7 13.6 18.2 18.2 14.3 13.7 11.1 15.3 8.4 6.8 0.0 0.0 0.0 1.8 0.7 67.9 5.1 0.0 5.3 0.0 3.5 78.5 1.4 1.7 1.2 6.5 2.6 2.0 0.0 5.3 1.1 1.0 1.6 0.0 2.1 3.0 38.1 6.4 1.3 0.0 5.6 2.0 1.2 3.3 0.0 1.5 4.0 3.1 1.5 2.5 0.8 72.2 6.5 2.7 22.3 15.8 1.1 1.1 1.3 2.5 1.3 SBK1 Sbk ENSG00000188322 "SH3 domain binding kinase 1" Q52WX2 16 28292519-28323849 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 31.1;lymphoid tissue: 22.1;skeletal muscle: 39.6" "Cell type enriched" "Detected in many" 8 "Cone photoreceptor cells: 76.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 4.3;MAIT T-cell: 1.4;memory CD4 T-cell: 1.2;memory CD8 T-cell: 2.4;naive CD4 T-cell: 1.4;naive CD8 T-cell: 3.0;NK-cell: 1.4;T-reg: 1.4" "Group enriched" "Detected in many" 10 "NK-cells: 1.4;T-cells: 4.3" "Cell line enhanced" "Detected in some" "AF22: 15.3;AN3-CA: 11.0;NTERA-2: 15.8;REH: 16.7;SCLC-21H: 24.3;SH-SY5Y: 22.9" "Region enriched" "Detected in all" 5 "cerebellum: 306.7" NA NA "unprognostic (5.15e-2)" "prognostic favorable (6.88e-4)" "unprognostic (2.08e-1)" "unprognostic (6.22e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-2)" "unprognostic (5.71e-3)" "unprognostic (3.66e-3)" "unprognostic (1.17e-1)" "unprognostic (1.62e-2)" "unprognostic (2.87e-2)" "unprognostic (6.38e-2)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (3.50e-2)" "unprognostic (7.91e-2)" "unprognostic (5.03e-3)" 0.9 2.0 8.0 1.8 7.3 2.0 1.7 31.1 17.5 1.7 1.2 1.5 0.0 1.1 1.9 1.3 1.5 1.6 1.0 1.8 9.9 5.6 1.6 0.9 1.8 2.7 6.0 4.0 1.1 2.7 4.2 4.1 0.8 8.3 2.6 1.2 1.4 3.8 1.0 39.6 1.4 1.1 0.9 3.1 2.8 1.6 2.3 3.1 22.1 2.6 0.0 1.7 1.2 0.3 0.2 0.2 0.2 0.1 1.4 4.3 0.4 0.1 0.2 15.3 11.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.7 0.3 0.1 0.0 0.3 0.3 4.6 0.1 0.0 1.5 0.5 0.0 0.1 0.4 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.1 5.8 0.0 1.0 0.0 1.8 7.0 0.1 15.8 1.0 0.1 16.7 0.8 0.1 0.1 0.9 24.3 22.9 0.4 1.4 0.2 1.9 1.7 0.0 0.4 0.0 2.4 0.2 0.1 0.2 0.0 0.2 0.1 0.2 0.9 0.2 0.1 0.1 4.3 0.0 1.4 0.0 1.2 2.4 0.0 0.2 1.4 3.0 0.1 1.4 0.1 0.2 1.4 0.4 8.0 7.3 31.1 17.5 9.9 5.6 6.0 4.0 8.3 3.1 3.0 0.3 0.0 0.8 0.6 9.4 3.1 2.5 2.7 3.4 0.0 76.6 0.0 1.7 6.1 1.0 0.0 0.0 0.0 4.8 0.0 0.4 1.5 0.0 0.2 0.1 0.0 5.8 0.0 0.0 3.1 0.6 0.0 0.0 0.0 0.3 4.2 4.7 0.0 0.0 0.5 2.7 0.0 0.3 1.4 2.3 0.1 0.1 2.5 0.8 0.3 SBK2 SGK069 ENSG00000187550 "SH3 domain binding kinase family member 2" P0C263 19 55529733-55537089 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 27 "heart muscle: 45.7;tongue: 20.8" "Group enriched" "Detected in some" 6 "Early spermatids: 1.3;Late spermatids: 1.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.4;Hep G2: 3.2;MCF7: 4.5;NTERA-2: 8.9;RH-30: 8.3;U-2 OS: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030631 Enhanced NA NA "HPA030631: AB_10602088" "unprognostic (1.33e-1)" "unprognostic (1.85e-3)" "unprognostic (4.57e-1)" "unprognostic (3.49e-1)" "unprognostic (5.43e-3)" "unprognostic (4.18e-3)" "unprognostic (2.08e-1)" "unprognostic (6.58e-2)" "unprognostic (1.05e-1)" 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.7 20.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.4 1.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 4.5 0.0 0.0 8.9 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 4.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SBK3 SgK110 ENSG00000231274 "SH3 domain binding kinase family member 3" P0C264 19 55540656-55545543 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "heart muscle: 24.2" "Cell type enriched" "Detected in single" 25 "Cardiomyocytes: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.4;CACO-2: 3.3;CAPAN-2: 5.6;NTERA-2: 2.5;RH-30: 4.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA078322 Approved Mitochondria NA NA Mitochondria "HPA078322: AB_2732379" "unprognostic (2.15e-1)" "unprognostic (1.99e-3)" "unprognostic (2.71e-1)" "unprognostic (1.39e-3)" "unprognostic (7.52e-2)" "unprognostic (2.83e-1)" "unprognostic (5.47e-5)" "unprognostic (4.64e-3)" "unprognostic (7.24e-2)" "unprognostic (1.65e-1)" "unprognostic (3.38e-1)" "unprognostic (3.08e-3)" "unprognostic (1.21e-2)" "unprognostic (4.92e-2)" "unprognostic (2.41e-1)" "unprognostic (1.79e-1)" 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.1 24.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.8 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.3 3.3 5.6 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.8 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.0 0.0 0.0 2.5 0.1 0.6 0.2 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 1.3 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCYL1 "GKLP, HT019, MGC78454, NKTL, NTKL, P105, TAPK, TEIF, TRAP" ENSG00000142186 "SCY1 like pseudokinase 1" Q96KG9 11 65525077-65538704 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Syncytiotrophoblasts: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015015 Uncertain Supported Cytosol NA NA Cytosol "HPA015015: AB_1856643" "unprognostic (5.56e-2)" "unprognostic (1.16e-1)" "unprognostic (1.03e-1)" "unprognostic (3.99e-1)" "unprognostic (1.23e-2)" "unprognostic (7.87e-2)" "unprognostic (1.23e-2)" "unprognostic (5.06e-2)" "unprognostic (1.14e-1)" "unprognostic (7.23e-2)" "unprognostic (4.41e-1)" "unprognostic (4.29e-1)" "unprognostic (7.86e-3)" "unprognostic (6.49e-3)" "unprognostic (4.27e-1)" "unprognostic (8.29e-2)" "unprognostic (2.29e-3)" 24.1 35.5 24.1 20.2 24.4 22.8 49.4 24.6 47.3 25.0 21.6 19.0 27.8 22.5 26.9 30.0 24.1 26.7 21.4 35.8 25.1 21.1 24.1 61.4 22.4 22.9 21.7 23.9 34.1 40.7 27.0 24.3 30.7 19.6 24.7 14.3 24.9 34.0 30.3 51.2 23.6 19.8 23.0 17.1 24.7 24.4 31.4 20.6 18.0 27.3 20.2 20.2 24.9 24.1 10.7 15.5 27.9 13.7 11.1 14.7 12.1 19.9 17.2 13.9 19.2 25.5 22.3 19.0 24.8 33.8 29.7 23.3 24.8 12.1 14.4 25.2 32.2 25.3 18.3 14.6 18.7 10.4 16.9 18.7 16.9 18.9 28.4 36.3 11.1 24.5 30.8 18.5 25.5 19.0 21.0 19.4 14.9 17.6 20.4 18.4 43.5 14.8 25.6 13.3 13.5 24.1 15.1 10.8 26.4 18.3 17.9 12.9 13.6 15.3 33.9 27.0 8.9 33.6 14.1 19.1 23.6 15.9 38.2 14.6 28.3 19.7 15.0 27.4 9.3 16.5 1.9 13.7 17.6 14.7 13.2 11.8 10.0 13.8 14.6 15.5 10.7 11.2 10.5 27.9 11.1 8.5 11.3 9.5 12.1 24.1 24.4 24.6 47.3 25.1 21.1 21.7 23.9 19.6 20.6 17.9 11.8 17.1 26.0 19.5 23.4 5.6 15.3 10.7 13.6 19.2 11.8 53.7 31.5 31.7 20.6 21.5 42.3 0.0 37.5 60.7 33.0 37.9 25.3 33.7 33.9 15.9 29.3 23.4 18.4 17.2 42.3 21.4 28.7 44.1 26.8 20.3 31.3 24.6 42.8 30.5 17.4 12.9 34.2 22.4 22.6 20.3 115.9 19.1 29.9 27.8 SCYL2 "CVAK104, KIAA1360" ENSG00000136021 "SCY1 like pseudokinase 2" Q6P3W7 12 100267140-100341724 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021050 Approved NA NA "HPA021050: AB_1846175" "unprognostic (7.01e-3)" "unprognostic (3.04e-2)" "unprognostic (4.34e-3)" "unprognostic (4.01e-2)" "unprognostic (3.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.27e-2)" "unprognostic (8.19e-2)" "unprognostic (5.32e-2)" "unprognostic (1.31e-1)" "unprognostic (1.34e-2)" "unprognostic (1.93e-2)" "unprognostic (4.44e-1)" "unprognostic (2.72e-1)" "unprognostic (3.46e-1)" "unprognostic (1.60e-1)" "unprognostic (2.18e-1)" 22.7 20.3 19.6 17.5 16.8 19.8 18.3 21.0 20.2 16.9 23.5 13.9 19.5 20.9 18.9 23.7 26.2 16.2 17.3 20.2 13.7 15.2 26.1 35.1 21.2 15.9 12.6 15.7 19.0 19.4 28.1 30.3 31.3 16.2 19.8 28.6 13.3 22.0 17.8 24.6 17.9 23.2 18.5 14.8 19.0 20.8 17.4 11.5 31.7 17.4 16.1 20.3 28.0 21.4 4.4 8.1 13.3 8.1 10.8 7.5 4.7 18.0 13.9 22.6 18.7 14.5 15.4 21.7 18.6 20.2 17.0 14.4 13.3 9.3 11.3 8.9 22.1 11.7 15.5 17.6 13.1 20.4 17.6 12.0 36.2 9.6 9.6 12.9 16.8 35.6 11.4 20.8 19.1 22.2 20.3 21.2 12.6 19.0 9.6 18.1 13.7 14.0 14.7 14.6 10.2 16.0 11.1 16.7 10.9 15.6 28.8 14.4 13.2 21.5 21.8 17.3 24.9 31.8 13.4 21.0 14.8 8.6 13.9 11.9 11.4 15.2 13.9 7.4 12.0 16.9 13.3 6.1 11.7 5.3 8.1 6.8 4.4 5.7 5.0 8.1 3.4 6.3 6.5 8.6 10.8 6.5 2.6 7.5 4.7 19.6 16.8 21.0 20.2 13.7 15.2 12.6 15.7 16.2 11.5 14.9 29.9 10.4 18.0 31.9 17.5 26.5 10.2 13.4 29.6 19.2 25.5 25.0 5.0 14.4 4.8 18.2 24.5 23.3 18.6 17.8 16.2 30.4 27.6 33.4 21.9 14.3 20.8 14.1 31.4 3.1 12.4 26.2 15.1 19.0 29.0 10.4 18.6 31.7 14.5 21.0 16.7 0.0 16.1 21.8 10.3 30.4 49.7 14.1 31.2 40.6 SCYL3 "PACE-1, PACE1" ENSG00000000457 "SCY1 like pseudokinase 3" Q8IZE3 1 169849631-169894267 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005624 Approved Uncertain "Nuclear bodies,Microtubules" NA NA Microtubules "Nuclear bodies" "HPA005624: AB_1854916" "unprognostic (2.35e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-2)" "unprognostic (8.36e-2)" "unprognostic (7.13e-2)" "unprognostic (2.72e-3)" "unprognostic (1.31e-1)" "unprognostic (2.12e-2)" "unprognostic (2.85e-2)" "unprognostic (7.17e-2)" "unprognostic (8.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.20e-3)" "unprognostic (3.54e-1)" "unprognostic (1.75e-1)" "unprognostic (4.60e-2)" "prognostic favorable (8.85e-4)" 10.8 11.4 8.5 15.4 10.6 5.0 15.8 10.5 11.9 12.1 14.6 11.0 14.6 10.7 12.6 14.0 14.4 10.6 11.0 7.8 7.3 6.5 12.1 18.0 11.8 13.7 9.3 7.8 13.0 12.8 22.7 14.4 15.8 9.5 13.2 13.9 12.3 15.5 13.8 14.6 14.1 14.9 13.0 7.3 12.6 11.3 9.1 8.9 17.2 13.3 9.5 16.0 16.0 12.7 8.3 13.6 12.3 4.3 11.8 10.5 5.9 3.4 4.5 7.0 4.8 9.0 6.5 8.0 5.4 7.1 6.3 6.0 4.1 6.7 7.1 4.0 5.6 3.5 8.1 4.1 4.8 5.7 13.1 3.8 4.9 5.0 2.6 6.4 7.1 6.4 6.3 4.8 4.4 6.1 6.0 6.0 8.0 7.8 9.5 6.0 2.7 5.7 5.5 5.6 23.5 2.2 5.3 3.8 8.5 6.7 6.3 5.2 7.6 4.3 14.3 8.5 10.3 8.0 6.6 4.4 4.6 3.0 5.4 4.3 12.8 11.3 8.5 3.4 5.4 5.0 12.3 3.7 9.7 8.0 3.9 10.5 8.3 10.4 8.7 6.0 7.3 9.2 7.5 8.2 11.8 4.3 13.6 9.5 5.9 8.5 10.6 10.5 11.9 7.3 6.5 9.3 7.8 9.5 8.9 6.0 11.8 5.2 1.7 2.2 9.6 3.4 22.9 2.7 9.1 1.8 9.8 14.5 8.3 5.3 2.9 5.8 10.8 0.0 8.0 4.3 4.3 3.7 5.7 8.6 5.5 9.5 8.7 7.4 10.8 1.5 4.0 5.3 1.7 7.2 12.7 8.9 5.8 10.5 5.3 4.9 17.6 6.5 4.1 7.2 6.4 1.6 9.7 10.2 9.9 2.3 SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169246-134318112 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 141.3" "Cell type enhanced" "Detected in many" 5 "Ito cells: 455.4;Syncytiotrophoblasts: 484.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.7;eosinophil: 45.9;neutrophil: 26.2" "Group enriched" "Detected in many" 7 "granulocytes: 45.9;monocytes: 11.7" "Cell line enhanced" "Detected in many" "HHSteC: 51.2;RPTEC TERT1: 78.5;SK-MEL-30: 50.9;TIME: 61.1;U-266/84: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" NA NA "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: AB_2681407" "unprognostic (2.05e-2)" "prognostic favorable (5.26e-4)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (5.62e-2)" "unprognostic (4.03e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-1)" "unprognostic (5.82e-3)" "unprognostic (9.10e-2)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" 45.6 35.5 16.8 12.8 43.2 15.8 22.9 10.6 25.0 18.4 62.3 51.7 10.8 14.2 14.9 11.2 30.0 16.1 47.8 12.5 22.9 9.6 37.5 51.1 31.2 8.4 48.8 16.6 47.2 47.8 141.3 4.7 19.2 28.3 18.3 11.3 45.8 26.2 18.4 12.4 25.8 131.8 13.6 40.3 7.6 31.1 12.2 50.1 6.2 22.3 24.8 20.4 26.1 31.7 0.6 4.0 45.9 11.7 0.9 0.7 3.1 0.6 1.1 0.7 0.0 8.8 2.2 1.0 12.6 26.3 16.5 13.5 1.9 1.7 2.1 1.9 13.0 8.1 0.4 1.1 2.0 12.2 0.0 0.5 0.1 31.4 1.4 51.2 0.1 1.1 13.2 12.6 16.2 21.0 6.6 27.6 0.3 4.0 32.0 5.9 0.1 0.1 0.4 0.8 3.2 1.3 0.4 1.5 0.2 78.5 0.2 0.3 3.1 39.6 0.1 50.9 7.6 0.1 0.3 61.1 4.8 2.1 29.5 2.7 6.0 56.0 6.5 4.5 1.9 6.5 0.6 11.7 45.9 0.2 6.8 0.5 0.6 0.4 0.2 4.0 0.4 0.5 0.6 26.2 0.9 3.7 0.2 0.7 3.1 16.8 43.2 10.6 25.0 22.9 9.6 48.8 16.6 28.3 50.1 35.7 233.2 40.3 98.2 162.8 10.8 19.4 96.8 24.1 99.0 64.6 33.4 39.9 18.3 60.3 7.2 107.9 230.9 0.0 151.5 27.8 58.7 45.7 257.3 17.5 283.4 0.0 10.2 455.4 148.5 5.6 14.1 322.4 254.8 6.4 46.9 4.3 52.7 129.6 14.9 92.1 28.6 12.9 39.1 48.4 7.5 101.6 484.9 9.6 6.4 68.4 SGK2 ENSG00000101049 "SGK2, serine/threonine kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.1;kidney: 39.1;liver: 32.9" "Cell type enhanced" "Detected in many" 15 "Distal tubular cells: 64.6;Enterocytes: 26.9;Hepatocytes: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 10.3;CAPAN-2: 8.0;Hep G2: 10.4;OE19: 34.0;RPTEC TERT1: 14.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm NA NA Nucleoplasm "HPA008859: AB_2668159, HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favorable (5.65e-4)" 11.4 0.7 2.8 4.3 9.9 0.2 3.1 1.0 10.2 1.4 21.3 33.1 0.9 17.8 1.0 19.7 0.7 1.6 7.9 0.7 4.3 2.5 39.1 32.9 0.6 0.5 6.9 5.1 3.2 14.1 0.5 1.7 0.5 13.7 1.4 23.4 0.0 0.9 1.8 0.4 3.2 20.7 1.0 14.2 0.7 11.9 1.0 6.0 0.0 1.0 0.2 0.2 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.5 8.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 10.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 34.0 0.0 0.0 0.0 0.0 14.7 1.7 0.1 0.4 0.0 0.7 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 9.9 1.0 10.2 4.3 2.5 6.9 5.1 13.7 6.0 0.0 0.0 0.0 0.1 0.1 0.8 2.2 12.7 0.0 0.0 10.4 0.0 3.4 64.6 3.9 0.1 0.1 26.9 0.0 5.4 1.0 0.2 0.1 0.0 26.9 0.6 6.4 1.7 1.3 1.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 2.6 8.4 0.4 15.7 0.8 0.0 0.0 0.0 0.2 0.1 14.3 0.0 5.9 0.1 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66667596-66862022 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "monocytes: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006699, HPA027146" Supported Supported Nucleoplasm,Vesicles NA NA Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favorable (5.52e-6)" "prognostic favorable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favorable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 6.5 5.9 13.9 8.7 20.9 7.7 23.9 9.8 14.8 12.0 10.0 24.0 8.7 8.6 8.0 10.3 7.6 7.8 7.8 5.4 16.1 10.2 14.9 13.6 9.9 8.5 28.8 9.3 9.8 15.6 29.2 14.8 5.9 14.6 7.8 10.7 17.2 7.0 7.7 6.1 12.4 10.8 6.0 32.8 8.2 7.2 8.9 21.9 8.3 17.3 4.3 6.8 6.1 8.0 5.8 13.8 21.4 15.7 6.9 13.3 8.0 11.6 3.0 0.5 1.9 3.5 7.0 6.5 7.4 7.1 4.1 4.3 5.3 7.8 8.8 1.8 8.1 11.0 3.8 6.1 4.3 5.1 4.9 10.3 7.9 2.2 5.2 3.5 7.1 9.4 3.3 3.9 1.9 6.8 3.8 6.5 7.0 1.5 4.2 7.7 1.8 5.6 4.4 1.7 6.7 4.1 9.8 4.4 5.9 5.4 2.6 2.5 2.0 3.3 5.0 11.2 5.2 23.5 14.2 7.7 3.9 3.4 3.3 2.8 5.2 10.1 10.1 4.5 12.0 4.0 21.4 15.7 6.2 8.1 9.3 13.3 3.7 8.4 8.5 13.8 5.8 9.0 6.9 2.5 6.9 4.4 7.7 5.3 8.0 13.9 20.9 9.8 14.8 16.1 10.2 28.8 9.3 14.6 21.9 6.0 22.6 7.8 5.6 11.7 1.7 5.6 7.6 16.0 11.4 10.4 17.7 7.0 13.3 5.8 0.6 9.8 10.5 0.0 15.8 1.2 4.5 8.9 14.0 18.3 21.3 0.0 15.5 17.2 34.8 1.1 3.7 32.9 8.5 45.1 7.0 3.5 12.1 9.7 7.4 30.7 1.6 0.0 3.1 4.1 11.3 13.8 4.0 15.8 8.2 4.7 SIK1 "msk, SNF1LK" ENSG00000142178 "Salt inducible kinase 1" P57059 21 43414483-43427189 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Cell cycle, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 34.5" "Cell type enhanced" "Detected in many" 17 "Alveolar cells type 2: 112.3;Basal keratinocytes: 268.2;Melanocytes: 91.1;Suprabasal keratinocytes: 369.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "memory B-cell: 2.0;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 10 "B-cells: 2.0;dendritic cells: 1.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 16.9;HeLa: 28.1;hTCEpi: 21.8;LHCN-M2: 21.9;U-266/84: 15.9" "CAB023801, HPA038211, HPA078064" Approved Approved Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "CAB023801: , HPA038211: AB_2675894, HPA078064: " "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (3.31e-3)" "unprognostic (3.00e-1)" "unprognostic (5.02e-2)" "unprognostic (7.97e-3)" "unprognostic (1.51e-1)" "unprognostic (7.30e-3)" "unprognostic (2.35e-3)" "unprognostic (4.97e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-1)" "unprognostic (3.89e-1)" "unprognostic (9.94e-3)" "unprognostic (3.88e-2)" "unprognostic (2.89e-1)" "unprognostic (1.82e-1)" 8.8 2.3 3.0 3.6 3.0 5.9 7.5 3.0 3.0 13.5 3.0 3.0 3.0 0.0 3.0 3.0 12.9 5.5 10.7 7.1 3.0 0.8 3.0 12.3 5.4 3.0 3.0 3.0 13.7 7.3 3.5 5.7 8.2 3.0 3.9 0.1 3.0 4.6 9.8 5.0 34.5 3.0 3.3 3.0 4.0 5.3 3.0 3.0 3.0 3.9 3.0 3.0 10.5 6.1 2.0 1.6 0.0 0.1 0.0 0.1 0.1 0.5 1.7 2.0 0.0 0.1 0.8 0.8 0.9 0.3 1.7 1.3 2.4 0.0 2.5 0.7 0.2 9.5 11.2 1.6 16.9 1.0 0.1 0.5 0.7 28.1 0.9 2.3 0.7 0.1 1.0 21.8 0.4 5.2 9.9 0.3 0.0 0.1 0.5 21.9 0.1 0.4 1.7 0.8 0.0 1.5 0.0 0.3 2.5 1.9 6.3 0.0 0.0 11.0 1.9 0.4 0.3 1.1 0.3 3.7 0.4 2.0 0.1 0.0 4.3 15.9 0.5 4.7 2.1 0.4 0.0 0.1 0.0 0.1 0.0 0.1 2.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 3.0 3.0 3.0 3.0 3.0 0.8 3.0 3.0 3.0 3.0 26.8 112.3 2.4 0.6 268.2 0.2 9.3 7.6 9.4 17.0 12.2 0.0 0.5 0.0 2.8 0.0 2.2 14.2 0.0 1.8 1.0 5.2 0.4 18.5 7.8 1.7 0.0 26.6 1.8 3.7 0.0 0.0 4.0 91.1 2.8 15.1 0.5 5.0 23.0 0.0 0.0 0.1 0.0 10.8 0.0 0.5 369.5 2.1 1.3 18.6 1.0 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602391-111730853 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Cone photoreceptor cells: 62.8;Rod photoreceptor cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 32.8 10.7 10.1 6.6 17.2 4.0 22.5 10.6 17.3 10.0 9.9 15.1 5.2 7.7 9.5 7.0 7.9 9.7 12.7 14.5 10.5 10.3 14.6 24.4 13.6 5.4 9.7 9.9 16.4 37.8 22.0 28.6 7.5 11.9 8.4 8.3 14.9 15.4 8.6 35.1 8.7 7.7 8.7 9.6 5.8 19.6 4.2 13.0 4.4 11.1 7.9 5.8 8.6 10.0 2.2 2.7 2.8 3.6 2.2 3.5 2.1 5.9 4.0 7.0 7.5 34.8 10.3 4.1 5.2 7.5 4.0 4.6 13.4 6.4 4.7 7.3 6.1 4.7 8.4 5.4 3.9 5.2 3.5 2.3 5.1 3.5 6.6 7.5 4.9 3.3 10.0 5.8 5.8 7.6 8.0 4.7 4.7 4.7 6.9 6.2 2.8 5.1 4.5 2.4 5.0 3.9 6.9 7.4 5.6 8.9 5.4 3.3 7.7 7.7 3.1 3.1 6.6 7.7 4.0 6.5 8.8 5.3 5.6 7.1 2.0 1.5 9.9 2.8 7.0 5.9 1.1 3.3 2.8 3.5 3.6 1.9 2.0 2.5 2.5 2.7 2.2 1.4 2.0 1.4 2.2 2.9 1.5 2.4 2.1 10.1 17.2 10.6 16.4 10.5 10.3 9.7 9.9 11.9 13.0 17.9 32.3 9.1 6.7 13.1 14.4 16.6 22.9 13.4 11.4 15.7 62.8 3.5 5.0 7.1 12.4 18.0 9.5 46.7 6.7 4.1 14.4 5.8 9.2 34.2 4.8 30.2 17.3 9.8 12.4 9.7 10.6 8.6 18.6 2.8 10.2 13.3 9.2 8.6 13.8 20.7 60.3 0.0 13.7 3.2 5.9 10.5 4.3 7.4 9.9 6.5 SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967201-104029233 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 4 "Urothelial cells: 181.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015757 Approved Approved "Plasma membrane,Cytosol" NA NA 17000 "Plasma membrane, Cytosol" "HPA015757: AB_1857236" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.67e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.95e-1)" "prognostic favorable (3.95e-5)" "unprognostic (8.48e-2)" "unprognostic (3.95e-1)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" 15.2 11.2 13.7 11.0 36.7 14.6 16.1 16.7 13.1 16.6 19.0 9.9 10.9 9.1 17.0 12.1 40.2 12.1 13.6 17.2 10.6 7.1 14.9 12.2 17.1 10.1 11.2 13.4 17.2 12.5 22.6 13.1 17.4 12.8 19.3 13.6 11.4 19.8 12.7 19.3 16.6 15.5 29.8 13.0 12.1 15.7 10.2 12.8 12.0 15.8 21.6 12.5 24.9 23.6 1.4 2.2 6.5 1.4 1.3 3.6 0.7 21.6 12.7 15.1 10.8 16.4 22.9 6.4 13.5 18.0 10.1 9.5 8.0 23.3 11.5 8.5 13.9 8.6 23.6 8.0 17.1 14.8 9.2 11.0 11.7 10.4 6.7 12.3 13.9 10.1 11.7 22.5 13.6 39.9 14.1 18.1 7.5 14.6 8.0 13.2 7.5 9.7 7.7 3.7 14.0 8.1 9.5 18.6 6.0 13.2 25.0 3.5 6.2 11.7 11.4 11.2 8.0 5.9 10.1 27.3 7.4 7.8 13.6 15.8 9.7 11.8 7.3 11.0 18.8 4.7 1.2 1.4 3.3 3.6 1.2 3.6 1.1 2.2 2.2 1.2 1.4 1.5 2.5 6.5 1.3 1.0 2.2 1.4 0.7 13.7 36.7 16.7 13.1 10.6 7.1 11.2 13.4 12.8 12.8 166.7 108.1 23.8 57.3 50.6 27.3 89.7 28.1 66.9 138.8 41.8 23.6 27.8 3.3 28.4 6.3 53.4 45.3 23.3 46.5 11.5 39.3 60.5 32.5 21.7 17.3 23.8 17.7 41.7 24.0 11.0 43.1 31.1 8.5 37.9 31.8 23.4 61.5 54.9 59.4 11.3 24.1 6.5 34.9 42.3 39.1 59.8 43.8 21.8 29.4 181.1 SMG1 "ATX, KIAA0421, LIP" ENSG00000157106 "SMG1, nonsense mediated mRNA decay associated PI3K related kinase" Q96Q15 16 18804853-18926454 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Nonsense-mediated mRNA decay" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006870, HPA031623, HPA073972" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA006870: AB_1079725, HPA031623: AB_2673962, HPA073972: AB_2686648" "unprognostic (6.34e-2)" "unprognostic (5.88e-2)" "unprognostic (5.98e-2)" "unprognostic (2.66e-1)" "unprognostic (2.44e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-1)" "unprognostic (2.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (8.32e-3)" "unprognostic (7.28e-2)" "unprognostic (1.05e-1)" "unprognostic (2.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" 4.7 3.0 2.1 4.5 3.5 11.7 6.2 13.2 3.0 4.4 4.5 3.1 5.4 5.1 5.5 4.0 3.0 4.5 2.3 2.2 4.6 5.4 4.1 6.2 2.3 6.3 4.5 7.2 3.9 3.1 4.2 5.0 4.7 3.3 21.1 14.4 5.0 3.9 3.4 4.5 4.3 4.0 6.0 5.8 5.2 4.9 7.1 4.6 19.1 5.6 2.3 6.1 1.0 23.5 15.8 14.9 10.5 17.1 18.1 11.1 11.0 10.9 12.0 13.5 13.9 8.7 32.5 15.9 15.3 12.7 13.4 17.1 9.6 19.2 20.9 10.7 14.8 13.9 17.7 13.9 19.9 11.7 10.6 16.3 24.9 30.0 11.9 16.8 17.7 22.7 18.1 13.2 12.6 13.7 11.9 15.9 8.6 9.1 15.9 20.1 11.1 10.4 18.5 13.5 10.4 17.1 11.6 12.1 12.8 9.3 12.7 21.2 18.1 12.1 11.1 16.3 9.3 12.0 21.4 12.0 15.5 10.8 19.1 2.5 3.4 6.1 2.8 2.9 3.7 4.0 4.3 2.5 7.1 5.4 4.7 7.6 2.3 5.6 4.6 3.7 1.0 71.5 85.2 53.9 67.9 171.7 51.1 42.5 20.4 48.2 92.1 26.2 70.7 16.8 3.3 19.5 15.5 65.3 48.7 23.3 20.4 15.0 55.9 71.2 38.1 39.9 21.0 39.7 37.7 36.8 38.1 15.4 27.6 61.1 37.1 36.1 38.6 20.1 26.6 57.5 24.8 12.2 43.3 45.3 56.7 45.2 29.8 178.7 25.1 60.7 35.2 83.0 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Ito cells: 86.5;Sertoli cells: 122.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 51.9;TIME: 30.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 31.5 8.8 9.8 13.1 14.4 41.0 22.6 34.5 21.1 17.6 14.4 7.9 5.9 12.8 20.9 10.5 16.2 11.5 16.4 13.9 11.0 11.0 16.8 20.3 24.7 19.8 11.4 10.6 15.1 18.0 18.4 16.2 26.2 22.5 12.1 9.9 14.7 10.7 9.4 12.5 24.5 17.0 18.7 9.8 25.4 11.2 13.9 7.2 48.4 24.8 13.5 14.4 15.8 19.3 3.2 3.0 20.9 5.5 8.1 10.7 6.5 3.3 2.0 3.8 3.6 11.3 4.0 3.6 3.6 6.1 3.9 3.8 2.8 4.8 5.3 2.8 4.5 2.6 2.1 4.4 7.7 4.1 6.0 3.6 6.0 3.8 3.2 5.9 6.7 6.7 4.5 5.3 4.4 7.5 4.0 51.9 6.1 2.6 6.1 3.5 1.7 6.8 5.9 4.2 1.8 9.3 4.7 2.8 5.5 10.1 5.7 2.7 5.6 3.1 3.3 4.3 3.4 2.3 8.6 30.2 3.4 3.5 3.9 4.1 9.9 7.1 4.5 2.4 8.1 4.9 4.8 2.8 5.4 7.6 5.5 10.7 2.8 6.7 7.6 3.0 3.2 10.1 10.1 20.9 8.1 5.0 0.9 7.1 6.5 9.8 14.4 34.5 21.1 11.0 11.0 11.4 10.6 22.5 7.2 29.8 30.3 12.9 9.7 46.9 49.8 14.5 22.9 16.0 18.2 15.7 15.7 6.3 10.0 9.2 40.0 52.3 28.4 0.0 7.8 2.7 11.8 9.9 13.9 21.3 11.3 28.6 10.4 86.5 27.6 4.9 11.5 16.6 21.9 4.6 8.9 15.6 8.4 8.2 11.0 10.4 17.2 122.9 26.4 10.7 15.7 44.8 6.9 41.7 8.5 15.4 SPEG "APEG1, BPEG, KIAA1297, MGC12676, SPEGalpha, SPEGbeta" ENSG00000072195 "SPEG complex locus" Q15772 2 219434846-219498287 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 88.7" "Cell type enhanced" "Detected in many" 9 "Cardiomyocytes: 55.0;Late spermatids: 30.8;Sertoli cells: 45.3;Smooth muscle cells: 36.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 27.9;U-87 MG: 14.6" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles NA NA Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 7.7 7.1 10.1 9.1 7.7 1.2 4.2 10.4 9.8 19.2 45.1 4.1 10.5 5.7 31.6 14.1 13.5 19.0 17.4 17.8 8.7 5.3 2.0 1.4 3.0 1.7 4.0 8.0 7.0 2.9 4.7 10.5 4.8 5.5 16.7 4.5 6.7 7.8 23.0 88.7 2.2 9.2 45.2 9.1 1.9 16.1 3.0 3.9 0.0 2.0 16.8 1.6 22.5 12.6 0.0 0.3 0.0 0.0 0.0 0.5 0.7 3.6 0.3 1.8 3.1 0.9 2.9 1.2 7.7 5.2 5.2 3.9 2.8 1.3 0.0 2.8 5.6 2.9 4.5 1.5 1.8 2.0 0.4 1.2 0.4 3.3 0.1 1.3 0.0 0.6 8.2 2.7 4.7 1.1 27.9 0.0 2.0 2.7 0.0 3.7 1.0 0.0 11.0 3.9 0.1 1.4 1.8 4.2 0.6 5.0 0.0 2.1 9.6 0.5 0.0 0.1 9.2 0.3 0.1 0.1 13.0 13.2 1.5 12.1 0.4 0.0 0.1 14.6 0.1 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.7 10.1 7.7 10.4 9.8 8.7 5.3 4.0 8.0 5.5 3.9 0.0 2.1 0.0 5.6 2.9 1.1 55.0 5.1 0.0 0.0 1.8 2.0 0.8 0.0 1.2 17.7 1.4 5.9 0.0 1.0 0.7 8.5 2.7 0.0 2.4 1.0 4.8 6.4 3.7 6.6 30.8 9.8 1.7 3.3 1.8 3.3 6.5 0.3 2.9 17.7 2.3 0.8 45.3 36.2 1.1 2.6 1.3 1.1 0.0 2.4 3.5 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "intermediate monocyte: 5.3;non-classical monocyte: 4.4" "Group enriched" "Detected in many" 6 "dendritic cells: 3.0;monocytes: 5.3" "Cell line enhanced" "Detected in many" "A549: 35.9;HBEC3-KT: 33.4;RT4: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA 20000000 "Plasma membrane, Cell Junctions" "Nucleoplasm, Cytosol" "CAB004023: AB_2106059, HPA030875: AB_2673640" "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.63e-4)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favorable (5.22e-5)" 6.9 17.5 12.8 11.1 12.0 5.4 9.9 6.4 16.0 16.0 16.4 3.5 15.1 29.5 20.3 9.7 16.2 14.2 42.1 5.8 11.3 6.6 13.4 2.9 10.4 7.0 3.3 9.9 15.8 19.1 6.6 11.3 6.3 5.1 19.9 13.1 13.1 7.5 22.5 3.4 7.7 28.1 27.2 3.6 12.2 29.8 27.3 4.8 4.0 6.6 10.5 10.4 26.4 20.0 0.3 3.0 0.1 5.3 0.6 0.1 1.6 7.7 35.9 8.3 7.4 3.1 5.0 17.2 7.2 6.2 8.8 5.6 13.5 7.0 0.2 4.5 13.0 10.0 14.2 4.9 33.4 3.4 0.0 4.5 2.0 1.3 20.9 7.5 0.1 3.1 5.3 11.4 5.7 7.7 9.8 8.0 4.6 0.2 0.0 1.4 5.3 1.9 0.2 3.9 21.5 32.6 8.4 2.2 0.2 3.7 34.4 7.7 27.9 8.1 11.4 8.9 6.6 10.2 2.8 11.6 10.5 7.1 3.8 6.4 0.1 0.2 0.1 7.4 0.0 7.8 0.0 2.6 0.0 0.0 5.3 0.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.1 0.6 4.4 3.0 0.1 1.6 12.8 12.0 6.4 16.0 11.3 6.6 3.3 9.9 5.1 4.8 3.0 1.7 4.4 10.8 7.2 5.4 1.6 15.3 1.4 0.0 12.2 2.0 1.6 1.7 9.7 1.3 1.4 30.0 0.0 16.2 7.0 8.2 11.2 0.0 0.9 5.8 3.2 16.1 1.3 6.9 1.5 10.0 12.1 1.7 7.2 25.9 4.1 29.0 18.1 16.3 9.5 4.7 12.9 6.4 0.2 0.7 8.0 1.9 0.0 14.9 27.7 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 10.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in single" "naive B-cell: 1.1" "Lineage enriched" "Detected in single" 8 "B-cells: 1.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.5;MCF7: 4.7;OE19: 7.0;RT4: 9.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: AB_2686650" "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.3 0.0 0.3 0.5 0.3 0.0 1.1 1.1 0.3 0.3 1.8 0.3 0.3 0.4 0.3 10.2 0.4 0.0 0.3 0.3 0.3 0.0 0.9 0.3 0.3 0.3 0.3 0.3 0.3 2.7 0.0 0.3 0.3 0.3 2.2 0.0 0.3 2.5 0.3 0.3 1.7 0.8 0.3 0.3 2.5 4.2 0.9 0.3 0.3 0.3 0.3 0.8 1.5 0.3 1.1 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 5.5 0.2 2.2 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.2 0.0 7.0 0.8 0.0 0.2 0.0 0.0 9.7 0.8 0.9 0.3 2.0 0.4 0.0 2.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 1.1 0.3 0.3 0.0 0.3 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SRPK1 SFRSK1 ENSG00000096063 "SRSF protein kinase 1" Q96SB4 6 35832966-35921342 "Enzymes, Predicted intracellular proteins" "Chromosome partition, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 8 "Early spermatids: 311.7;Late spermatids: 401.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016431, HPA056486" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Nucleoplasm, Cytosol" "Plasma membrane" "HPA016431: AB_1857478, HPA056486: AB_2683148" "unprognostic (4.65e-3)" "unprognostic (6.82e-3)" "unprognostic (2.54e-3)" "unprognostic (1.01e-3)" "unprognostic (7.74e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.23e-2)" "unprognostic (2.54e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (6.53e-5)" "unprognostic (7.28e-2)" "unprognostic (2.21e-3)" "unprognostic (9.24e-2)" "unprognostic (4.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.55e-3)" 13.5 7.1 8.1 15.4 11.7 32.1 11.7 22.5 17.8 12.8 23.8 7.8 10.8 20.3 15.2 7.9 24.9 8.9 10.8 8.7 8.9 7.8 17.8 18.9 14.9 14.6 8.0 8.3 9.5 26.0 11.7 17.7 27.9 9.6 10.5 28.7 12.4 17.6 9.4 19.9 26.2 25.7 11.3 7.9 19.0 13.9 32.7 7.6 21.0 8.5 17.0 19.8 15.2 15.7 4.3 2.8 24.6 3.4 5.0 6.7 2.9 29.9 11.4 16.8 25.0 9.4 12.3 21.2 18.4 17.8 17.2 18.3 32.0 10.1 40.0 15.6 11.3 20.0 15.4 32.8 21.9 31.0 27.3 23.6 21.0 13.4 27.7 8.3 31.1 10.4 7.9 12.0 19.8 26.0 13.7 21.6 22.9 44.5 17.0 14.4 10.6 32.0 24.2 13.7 18.3 12.5 22.5 20.1 24.7 17.3 50.4 35.8 13.1 18.9 18.0 12.7 17.8 10.1 20.7 15.6 16.2 12.7 11.0 23.1 10.0 22.1 37.6 6.4 36.1 14.4 24.5 2.1 13.7 4.3 2.5 6.1 4.3 5.7 5.7 2.8 3.3 4.8 5.2 24.6 5.0 3.4 1.6 6.7 2.9 8.1 11.7 22.5 17.8 8.9 7.8 8.0 8.3 9.6 7.6 8.9 26.3 24.4 65.1 37.5 33.6 21.8 12.7 32.1 38.7 21.0 35.3 43.2 24.9 50.7 311.7 24.1 38.6 23.3 58.8 43.3 21.3 68.6 7.0 40.0 19.1 9.5 44.4 11.1 17.1 401.7 20.4 16.9 15.1 36.1 44.8 13.4 78.7 42.1 23.3 44.4 84.4 6.5 23.1 154.9 90.6 36.5 33.2 34.8 87.4 132.9 SRPK2 SFRSK2 ENSG00000135250 "SRSF protein kinase 2" P78362 7 105110704-105399308 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 69.3" "Group enriched" "Detected in many" 6 "Early spermatids: 1076.1;Late spermatids: 1865.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 58.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 58.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015522, HPA020876" Enhanced Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA015522: AB_1857479, HPA020876: AB_1857480" "unprognostic (9.75e-2)" "unprognostic (1.68e-2)" "unprognostic (1.12e-1)" "unprognostic (4.64e-2)" "unprognostic (3.54e-1)" "unprognostic (1.30e-1)" "unprognostic (5.14e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" "unprognostic (2.31e-1)" "unprognostic (5.38e-2)" "unprognostic (7.95e-2)" "unprognostic (4.72e-2)" "unprognostic (2.87e-2)" "unprognostic (3.44e-1)" 9.9 12.1 24.8 10.1 27.6 7.1 13.3 28.4 47.1 12.7 9.4 21.0 7.8 8.2 13.2 11.9 11.9 10.9 11.6 10.4 26.4 28.6 10.3 10.1 9.2 11.5 27.2 30.2 13.0 10.5 11.9 15.3 12.0 27.3 14.0 10.9 7.9 10.1 11.1 7.9 16.9 8.2 13.3 23.1 12.0 11.3 69.3 32.3 22.1 11.3 4.7 14.0 13.6 9.7 12.2 7.3 58.2 8.1 10.0 11.9 6.0 13.3 8.9 14.2 28.1 15.2 17.2 7.9 13.1 15.3 13.1 15.3 6.9 11.4 8.5 16.7 16.9 14.7 8.0 14.3 13.8 16.8 14.7 12.7 12.0 8.4 6.0 17.6 11.4 18.0 11.9 25.7 11.1 20.9 12.7 22.5 20.3 11.8 34.8 14.5 25.2 42.2 8.7 11.7 7.6 9.7 13.7 15.6 18.4 18.9 20.7 20.8 14.4 14.8 22.3 13.8 19.6 8.3 8.0 14.7 24.2 17.6 23.0 12.2 38.2 37.6 20.9 9.5 11.8 18.0 11.2 8.1 26.0 11.9 5.5 7.1 12.2 9.0 8.9 7.3 11.6 8.5 9.7 58.2 10.0 6.2 6.4 10.1 6.0 24.8 27.6 28.4 38.7 26.4 28.6 27.2 30.2 27.3 32.3 26.8 28.5 33.3 51.2 189.1 70.3 20.1 33.1 48.2 27.3 22.7 47.1 40.1 23.2 44.1 1076.1 52.5 12.9 0.0 40.5 30.6 44.1 65.7 40.4 25.1 41.0 117.6 27.6 43.0 45.7 1865.0 71.1 31.8 55.6 40.5 32.1 65.3 32.7 21.0 90.2 21.7 65.2 45.3 45.3 237.2 50.3 90.3 53.9 56.8 23.6 46.7 SRPK3 "MSSK1, STK23" ENSG00000184343 "SRSF protein kinase 3" Q9UPE1 X 153776412-153785732 "Enzymes, Predicted intracellular proteins" "Differentiation, Myogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 73.4" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 23.8;Cone photoreceptor cells: 7.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in single" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RH-30: 31.4;U-266/70: 13.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "unprognostic (1.79e-3)" "unprognostic (6.21e-2)" "unprognostic (1.79e-2)" "unprognostic (7.24e-2)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-1)" "unprognostic (4.47e-4)" "unprognostic (2.83e-1)" "unprognostic (1.71e-1)" "unprognostic (4.10e-4)" "unprognostic (8.70e-2)" "unprognostic (5.38e-7)" "unprognostic (1.97e-2)" "unprognostic (1.97e-1)" "unprognostic (3.83e-2)" "unprognostic (1.07e-4)" 1.6 1.8 1.3 0.9 1.8 0.8 0.3 7.7 1.5 0.9 4.5 1.1 0.2 1.3 2.5 3.3 2.6 0.7 1.7 16.7 2.0 1.8 0.2 0.2 0.4 0.8 2.0 0.7 0.7 0.7 1.0 5.8 0.3 1.1 2.8 0.8 0.9 2.9 0.5 73.4 2.3 1.3 4.0 2.0 0.8 1.3 0.5 0.9 0.3 0.6 18.3 1.6 2.0 0.8 0.4 2.6 0.9 0.3 0.1 0.6 0.3 3.2 4.4 0.8 2.2 0.0 0.1 1.0 0.4 0.0 0.2 0.0 3.7 0.6 3.3 0.4 0.4 0.3 0.9 0.0 0.1 0.0 2.8 3.1 1.7 2.7 0.6 0.0 0.8 5.1 2.8 0.0 0.0 0.0 0.2 0.0 4.7 2.2 3.9 0.9 7.0 0.6 4.8 0.8 0.2 1.2 1.5 31.4 0.9 0.0 1.5 5.3 2.5 0.0 2.3 1.0 0.3 2.9 3.8 0.1 1.2 2.8 2.3 0.4 13.0 2.1 2.2 0.6 6.2 1.6 0.8 0.3 0.2 0.5 0.1 0.6 0.2 0.1 0.1 0.0 0.4 0.1 0.1 0.9 0.1 0.0 2.6 0.0 0.3 1.3 1.8 7.7 1.5 2.0 1.8 2.0 0.7 1.1 0.9 0.0 0.0 0.0 1.0 0.6 2.2 23.8 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.7 0.0 0.0 2.8 0.0 0.2 0.0 2.7 0.0 0.1 0.4 0.0 0.0 0.2 0.3 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042073-172188386 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" 7 "Kupffer cells: 78.5;T-cells: 70.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 27.5" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 24000 "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: AB_2669151" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favorable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 15.0 4.7 2.6 25.8 4.4 38.3 13.5 27.5 3.0 3.6 5.0 4.8 3.4 4.7 4.4 4.4 3.6 4.2 11.0 9.0 2.4 2.5 5.3 4.5 15.4 40.9 5.4 1.9 3.5 4.1 2.5 3.7 16.2 4.5 4.3 4.0 5.6 7.8 2.5 3.1 9.0 12.2 5.7 4.6 33.0 6.2 13.1 3.5 20.6 4.6 3.1 23.7 9.5 11.3 5.0 10.3 22.3 30.8 7.4 18.0 15.6 7.8 7.3 4.5 6.8 5.3 6.6 11.6 10.2 8.5 7.4 6.9 3.8 10.4 9.5 5.4 12.6 15.7 9.2 2.0 12.5 4.8 12.3 3.4 11.4 3.0 2.1 7.6 11.5 13.5 6.5 2.7 10.1 8.4 2.7 6.4 3.7 1.0 13.3 5.2 12.6 8.2 25.8 1.8 3.9 5.8 13.6 3.6 6.2 3.0 9.9 3.1 3.8 5.9 8.3 28.0 5.9 2.9 24.4 8.9 8.3 4.2 5.8 5.5 11.2 16.5 6.0 10.9 17.7 52.3 7.1 10.8 10.0 18.0 21.4 13.3 5.0 9.4 12.8 10.3 4.4 5.6 9.6 22.3 7.4 30.8 3.2 12.2 15.6 2.6 4.4 27.5 3.0 2.4 2.5 5.4 1.9 4.5 3.5 3.0 12.8 25.0 7.9 6.0 3.8 3.6 2.5 5.3 5.7 1.8 5.9 2.8 1.7 4.4 1.7 17.8 8.4 0.0 5.3 25.1 7.4 6.7 26.7 2.1 30.8 44.5 11.5 20.3 78.5 2.7 2.6 39.2 8.5 9.0 15.0 3.1 7.9 7.0 1.4 1.5 2.2 12.9 8.2 5.7 6.8 3.6 4.2 70.5 4.7 9.5 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228435 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 11 "Early spermatids: 124.0;Late spermatids: 234.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "neutrophil: 11.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847" "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favorable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 13.4 13.7 13.5 11.8 12.4 19.3 16.7 17.8 16.0 12.2 16.1 8.3 19.8 18.1 10.8 8.7 15.1 10.0 11.8 15.3 12.6 9.8 10.7 22.1 9.4 12.5 9.7 10.4 11.0 16.8 10.7 11.6 12.2 9.9 12.2 5.3 11.9 16.0 12.2 49.2 16.8 18.0 7.7 7.6 16.9 15.5 59.8 7.5 11.8 12.4 14.5 19.0 11.4 9.8 2.7 1.9 11.7 6.3 1.9 1.8 0.5 21.2 10.3 7.8 14.8 7.4 6.7 16.5 10.4 10.9 9.8 10.4 8.4 14.9 13.9 11.5 10.8 4.4 13.8 7.7 16.0 3.0 26.0 18.8 14.2 0.6 10.5 16.0 14.3 23.9 12.2 11.7 7.5 11.2 8.9 9.8 11.1 26.6 19.2 5.5 15.9 13.7 14.5 15.0 7.3 12.7 21.8 8.4 15.6 8.8 15.6 18.1 13.1 0.0 7.7 11.2 4.7 12.1 23.5 13.2 10.1 11.5 19.8 16.5 37.8 15.9 10.4 10.1 19.1 10.4 2.0 4.2 4.5 0.6 6.0 0.4 2.7 1.0 1.8 1.9 1.0 1.0 0.9 11.7 1.9 6.3 1.0 0.7 0.5 13.5 12.4 17.8 16.0 12.6 9.8 9.7 10.4 9.9 7.5 6.0 13.6 11.1 6.4 14.8 23.6 11.8 17.8 2.7 6.8 22.7 17.7 6.7 6.6 8.1 124.0 14.7 29.5 0.0 11.9 4.5 10.4 14.2 2.3 25.2 12.9 17.5 14.5 16.0 22.2 234.7 22.7 10.4 15.1 17.2 29.2 19.3 13.0 25.9 19.4 8.6 19.8 12.9 20.8 49.9 19.4 13.6 7.3 8.6 33.0 10.9 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA Cytosol "Nucleoplasm, Plasma membrane" "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favorable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 10.2 19.0 15.7 12.8 20.3 13.3 14.6 8.8 21.0 11.5 16.2 15.2 20.5 17.2 11.4 22.1 16.0 18.3 15.5 13.0 14.5 11.9 19.5 30.1 11.4 24.6 14.2 13.2 13.2 24.5 16.5 15.1 14.0 13.3 14.3 13.7 12.8 19.0 16.3 9.9 12.2 14.2 11.5 12.3 15.9 16.8 18.9 12.7 27.2 19.8 12.8 17.0 12.9 10.3 7.9 7.8 5.8 7.6 14.5 11.2 9.7 7.4 9.8 8.6 7.3 21.5 21.0 9.9 9.6 13.3 8.2 8.2 11.4 16.6 4.3 13.5 16.0 13.1 7.7 10.0 16.0 4.4 10.5 11.5 9.7 8.9 9.8 19.5 9.2 11.4 22.4 25.7 11.3 29.9 16.2 9.9 10.1 12.1 11.8 14.0 13.7 10.0 20.1 8.0 13.5 6.0 9.5 9.7 12.6 17.1 8.6 6.9 8.8 3.4 13.7 19.7 6.5 14.3 19.5 7.6 11.2 7.9 9.1 9.2 14.6 6.2 10.3 12.4 9.8 9.8 2.0 7.6 5.8 6.0 4.2 6.8 7.8 7.5 11.2 7.8 7.9 7.8 10.0 5.2 14.5 3.6 6.7 8.4 9.7 15.7 20.3 8.8 21.0 14.5 11.9 14.2 13.2 13.3 12.7 6.0 6.4 22.9 15.0 8.8 7.4 7.8 28.1 5.3 5.7 7.0 15.7 20.2 58.0 33.5 69.7 11.7 27.6 0.0 51.6 21.3 17.4 15.1 8.1 39.4 25.1 12.7 24.8 11.6 19.1 56.4 14.1 15.7 20.3 43.3 36.3 18.3 30.3 42.9 12.7 72.1 18.4 0.0 12.2 38.1 6.9 9.8 10.8 30.5 35.9 14.0 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43626786 "Enzymes, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 43.3" "Cell type enhanced" "Detected in many" 10 "Basal glandular cells: 549.3;Urothelial cells: 279.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Nuclear speckles" "Plasma membrane" "HPA018138: AB_2669784, HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 7.1 10.1 6.1 43.3 8.2 20.2 8.4 7.9 7.2 4.8 9.3 3.7 2.0 6.1 5.3 4.2 10.1 4.7 8.6 17.7 5.7 5.6 6.7 8.1 15.2 36.6 6.6 2.6 7.3 14.3 1.5 6.3 37.2 5.7 6.2 5.3 3.6 8.6 3.4 10.7 4.8 12.3 5.8 5.3 27.8 11.0 9.0 2.8 30.1 7.3 6.8 37.7 10.3 8.1 10.8 1.4 11.5 0.9 12.7 11.4 2.9 4.4 5.5 5.0 3.4 6.3 8.3 2.1 15.9 17.3 8.7 8.9 4.8 3.2 7.1 25.1 13.3 17.8 9.1 3.8 21.2 12.2 17.5 4.3 6.3 4.1 5.9 4.7 10.8 4.2 6.8 25.0 11.5 10.6 34.5 16.3 7.7 7.4 24.4 10.0 2.0 17.6 5.0 7.7 2.6 18.1 6.1 3.2 14.0 15.2 3.3 2.7 6.1 7.2 3.3 4.6 10.7 3.8 5.5 16.3 19.0 7.2 11.2 17.8 14.8 7.3 10.2 19.3 9.6 30.2 0.7 0.4 11.5 5.8 0.2 5.8 10.8 6.1 9.7 0.3 10.1 11.4 10.2 6.4 12.7 0.9 1.4 3.2 2.9 6.1 8.2 7.9 5.9 5.7 5.6 6.6 2.6 5.7 2.8 113.2 27.8 121.1 549.3 161.6 3.0 25.4 5.1 52.2 81.9 19.2 9.8 44.4 28.2 110.3 36.3 19.4 29.1 0.0 82.8 19.7 31.9 134.1 39.1 7.7 15.8 0.0 6.9 16.5 16.2 8.8 5.5 19.9 33.7 55.1 27.8 8.1 75.9 56.1 2.5 9.7 25.2 6.5 55.6 45.1 29.6 118.9 55.8 186.8 10.0 279.4 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133566-196176503 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 62.0;bone marrow: 103.4;lymphoid tissue: 72.2" "Cell type enhanced" "Detected in many" 5 "B-cells: 158.6;granulocytes: 189.5;Kupffer cells: 142.8;Macrophages: 145.8;T-cells: 178.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 36.3;HMC-1: 36.8;Karpas-707: 34.1;U-698: 39.5" "Region enriched" "Detected in many" 6 "cerebellum: 71.1" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" NA Yes "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 21.0 4.1 3.2 42.8 3.8 103.4 10.1 3.2 3.3 8.2 18.8 1.1 3.8 8.5 3.4 3.9 8.9 6.3 8.6 5.7 3.3 2.2 7.2 2.9 26.2 53.7 2.3 1.8 3.1 5.0 0.7 3.8 6.5 1.7 6.8 5.7 3.5 16.7 6.1 3.4 10.9 31.8 5.3 2.7 59.3 6.0 4.6 1.4 72.2 7.5 7.0 56.2 11.3 6.0 16.9 13.6 62.0 27.0 10.3 28.4 19.0 3.2 2.2 3.4 1.2 15.0 5.7 3.8 7.7 11.6 8.5 8.9 6.8 1.1 36.3 7.1 4.4 2.2 2.2 1.4 3.3 10.4 6.4 3.8 3.4 2.9 0.6 4.5 13.7 36.8 7.2 3.3 10.5 5.5 12.1 3.5 8.6 2.6 34.1 21.1 1.7 17.8 31.0 1.9 5.9 5.2 2.9 20.7 11.0 5.0 7.6 1.3 1.3 1.9 1.9 1.6 5.5 1.3 7.2 4.2 8.3 4.1 5.9 4.3 14.0 22.6 39.5 6.2 4.7 3.6 35.9 19.7 40.2 12.0 20.7 15.3 13.3 21.5 14.5 13.6 16.9 28.4 23.1 62.0 10.3 27.0 9.7 18.5 19.0 3.2 3.8 3.2 3.3 3.3 2.2 2.3 1.8 1.7 1.4 83.4 80.3 158.6 22.9 53.1 0.3 2.2 10.2 34.8 52.4 10.4 0.0 5.9 3.3 5.2 4.6 11.6 59.1 46.7 2.5 20.9 21.2 28.7 189.5 2.4 23.5 0.0 2.9 7.4 142.8 2.0 5.2 145.8 55.6 40.5 11.0 0.9 7.9 38.6 4.2 1.4 0.2 6.5 20.5 28.6 24.9 55.5 4.2 178.5 10.5 39.9 STK24 "MST-3, MST3, MST3B, STE20, STK3" ENSG00000102572 "Serine/threonine kinase 24" Q9Y6E0 13 98445185-98577940 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026435, HPA026502" Enhanced Supported Nucleoli,Cytosol No No 2800000 "Nucleoli, Cytosol" "HPA026435: AB_1854151, HPA026502: AB_1854152" "unprognostic (3.49e-2)" "unprognostic (2.39e-2)" "unprognostic (1.78e-1)" "unprognostic (3.44e-2)" "unprognostic (2.86e-1)" "unprognostic (3.25e-2)" "unprognostic (9.67e-3)" "prognostic unfavorable (6.23e-6)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.81e-4)" "unprognostic (9.62e-2)" "prognostic favorable (6.91e-5)" "unprognostic (3.10e-2)" "unprognostic (4.49e-2)" "unprognostic (3.88e-2)" "unprognostic (1.12e-2)" 28.6 14.2 15.0 29.7 16.9 19.1 34.8 12.2 21.0 36.3 37.4 12.1 23.0 31.9 24.6 26.5 68.4 20.4 41.3 30.0 14.7 12.8 30.5 14.2 23.9 31.2 10.6 10.1 20.0 20.6 12.4 13.9 38.4 14.7 28.3 28.8 36.8 30.8 21.6 18.8 60.6 67.9 34.8 9.2 31.7 30.2 22.1 7.6 38.2 28.2 41.6 48.5 39.2 45.4 8.1 11.2 11.4 13.4 1.5 13.7 6.7 36.0 11.3 20.0 18.5 30.8 18.5 28.5 16.9 23.8 23.7 23.2 33.0 49.1 25.7 8.6 21.1 14.9 32.7 18.5 37.3 22.7 64.1 9.5 27.5 14.4 18.9 43.6 27.6 19.5 11.9 59.6 18.6 54.9 25.1 20.4 20.3 9.9 17.8 15.5 15.7 20.6 11.4 17.9 49.1 8.5 26.1 12.3 13.9 22.9 32.6 11.7 16.8 10.7 17.3 22.8 31.9 20.8 26.9 27.4 15.1 11.0 12.3 19.4 17.4 9.1 9.6 23.5 16.7 24.8 5.8 13.4 6.1 6.1 10.6 7.2 6.6 11.4 8.7 11.2 8.1 7.8 6.1 11.4 1.5 12.7 7.5 13.7 6.7 15.0 16.9 12.2 21.0 14.7 12.8 10.6 10.1 14.7 7.6 11.9 24.3 29.0 62.3 63.0 20.3 2.8 68.8 34.8 44.3 64.6 53.0 35.6 21.6 29.9 2.5 26.3 110.9 0.0 47.8 36.3 36.7 53.4 18.4 22.9 24.7 9.5 40.9 27.0 68.7 3.4 24.7 40.1 54.0 16.2 70.9 22.1 67.8 59.4 28.7 31.9 11.4 38.8 29.0 1.8 3.6 71.8 16.7 21.8 51.8 117.9 STK25 "SOK1, YSK1" ENSG00000115694 "Serine/threonine kinase 25" O00506 2 241492674-241509730 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 164.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047147 Uncertain NA NA "HPA047147: AB_10966137" "unprognostic (1.75e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (6.03e-4)" "unprognostic (3.42e-2)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (3.91e-8)" "unprognostic (6.16e-2)" "unprognostic (7.15e-3)" "unprognostic (1.11e-1)" "unprognostic (2.58e-3)" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-1)" "unprognostic (3.19e-1)" "unprognostic (4.58e-1)" 17.8 13.6 22.3 14.2 26.0 16.3 12.9 22.3 35.3 16.4 17.1 17.0 13.0 14.6 17.7 15.9 19.3 15.4 16.7 19.0 19.4 20.0 17.3 13.5 13.4 13.5 16.3 20.4 17.5 19.2 18.9 17.1 15.6 16.4 15.1 12.9 13.5 14.2 17.6 164.2 15.3 14.2 17.3 12.6 15.8 16.1 16.8 14.4 15.2 20.0 24.6 12.6 14.6 16.6 15.0 13.6 13.7 16.4 21.5 19.9 10.6 18.7 11.9 23.9 29.6 29.4 20.6 36.7 31.3 21.1 23.9 27.4 13.3 16.6 7.1 8.8 41.7 21.7 16.0 33.6 34.1 29.1 26.7 35.3 20.0 25.3 34.3 26.7 12.1 15.5 29.5 24.5 23.1 18.6 29.4 53.9 26.4 30.8 6.4 43.7 19.7 18.0 18.9 33.3 17.5 17.2 30.3 30.4 10.7 21.0 15.9 40.2 18.4 15.2 11.5 19.6 28.3 9.2 21.6 62.8 18.1 22.1 20.7 22.2 13.2 2.9 12.1 17.5 10.0 20.5 13.7 14.8 11.5 16.9 13.4 15.5 14.5 15.5 17.5 13.6 15.0 12.0 11.6 5.5 21.5 16.4 10.7 19.9 10.6 22.3 26.0 22.3 35.3 19.4 20.0 16.3 20.4 16.4 14.4 20.8 36.6 14.1 25.2 22.7 49.3 31.3 33.1 16.0 19.4 24.4 25.5 71.0 23.2 38.2 10.6 44.7 31.6 46.7 29.7 65.7 31.3 25.3 25.3 21.2 39.2 30.2 34.0 44.8 29.8 9.6 30.2 21.3 18.6 65.9 34.9 46.4 36.1 52.6 37.4 37.8 36.1 45.3 29.9 72.8 32.6 26.6 43.8 25.4 41.9 24.5 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023265-132075943 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Cytotrophoblasts: 44.8;Syncytiotrophoblasts: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 41.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Yes No Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: AB_2684163" "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 5.4 1.4 1.1 13.5 5.1 25.9 3.3 3.8 1.1 18.0 6.4 0.3 34.8 3.7 42.3 29.6 11.7 6.0 5.2 1.9 1.2 2.3 3.5 3.2 6.7 12.8 1.2 0.3 4.7 4.0 10.2 5.8 50.7 1.2 11.5 4.8 2.2 6.3 22.4 1.2 5.1 6.1 19.1 1.5 8.5 4.7 5.2 0.8 44.7 2.3 6.8 10.2 18.0 6.6 8.4 6.2 26.4 11.6 22.0 13.3 10.2 9.1 3.2 0.4 0.0 1.5 1.4 21.0 0.3 1.1 0.1 0.1 8.4 8.3 12.5 5.7 2.0 6.5 10.4 23.4 14.7 0.0 10.8 19.1 18.0 7.9 7.9 1.4 37.6 1.5 2.0 8.8 0.0 9.9 4.4 4.1 17.2 8.0 11.8 3.5 8.1 38.7 35.0 18.8 6.2 1.2 28.0 11.6 16.1 9.5 14.8 7.8 8.6 5.5 5.0 0.2 17.0 6.4 9.9 0.1 3.8 4.0 11.4 13.5 9.1 14.2 13.9 3.4 41.0 1.9 26.4 5.1 16.6 13.3 6.7 13.0 8.4 9.1 11.3 6.2 7.3 11.8 12.2 10.0 22.0 11.6 2.3 4.0 10.2 1.1 5.1 3.8 1.1 1.2 2.3 1.2 0.3 1.2 0.8 20.8 14.1 8.6 27.8 0.0 0.0 1.1 5.1 12.0 14.8 10.4 0.0 44.8 3.3 4.4 0.4 0.4 0.9 0.0 6.3 28.5 4.9 17.5 10.5 3.0 10.7 0.0 1.2 0.6 10.1 0.0 3.1 7.2 0.0 9.0 6.4 0.0 8.6 3.5 2.1 1.2 0.0 6.5 2.9 1.1 2.3 0.0 49.4 17.5 6.3 15.3 STK3 "KRS1, MST2" ENSG00000104375 "Serine/threonine kinase 3" Q13188 8 98401403-98942827 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Early spermatids: 118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" 5 "dendritic cells: 8.3;granulocytes: 9.0;monocytes: 8.7" "Cell line enhanced" "Detected in many" "A-431: 37.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007120, CAB025316" Uncertain Approved "Intermediate filaments,Rods & Rings" NA NA "Intermediate filaments, Rods & Rings" "CAB025316: , HPA007120: AB_10601664" "unprognostic (7.88e-3)" "unprognostic (1.96e-1)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-4)" "unprognostic (2.95e-1)" "unprognostic (1.12e-3)" "unprognostic (9.68e-3)" "prognostic unfavorable (4.25e-4)" "unprognostic (6.71e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (9.21e-5)" "unprognostic (9.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (9.72e-2)" 16.5 16.6 6.5 8.1 12.4 2.5 20.5 2.6 10.6 17.2 13.1 10.5 14.2 4.6 22.2 13.1 9.0 16.0 12.6 10.0 7.4 4.1 14.7 12.0 16.2 10.8 12.8 3.6 22.8 10.7 15.1 18.9 53.1 9.9 15.0 6.0 8.2 10.8 16.4 11.6 10.0 10.8 23.5 12.9 8.2 9.5 10.1 11.4 3.4 10.6 7.9 5.9 16.4 24.3 1.9 8.3 9.0 8.7 1.8 1.8 2.9 37.3 7.0 7.5 9.8 24.2 12.1 7.5 13.0 11.7 12.2 10.6 5.2 15.9 0.0 11.4 12.9 6.4 15.1 5.2 11.2 19.7 9.0 6.6 10.0 3.5 3.5 8.3 3.3 8.7 8.0 19.4 6.2 17.0 8.0 5.2 5.9 4.2 5.4 8.8 4.7 8.3 4.0 2.2 25.8 2.7 7.4 6.4 3.2 13.8 4.7 1.9 4.3 8.3 9.6 8.0 10.0 7.9 5.4 3.9 8.2 5.2 12.4 7.2 4.3 6.5 2.7 7.4 4.2 13.0 2.1 8.6 4.5 1.3 8.7 1.4 1.9 0.8 1.8 8.3 1.3 1.1 0.7 9.0 1.8 5.4 3.4 0.1 2.9 6.5 12.4 2.6 10.6 7.4 4.1 12.8 3.6 9.9 11.4 35.7 32.0 4.7 38.6 38.8 6.0 15.1 22.9 33.5 42.1 27.9 13.7 36.5 19.9 17.3 118.9 30.2 17.6 0.0 16.5 49.2 41.3 37.6 16.2 18.4 16.1 9.5 8.7 22.1 14.6 63.7 84.3 20.2 23.6 7.2 7.6 15.1 19.7 9.5 69.6 20.3 14.2 38.8 39.6 17.0 11.9 35.4 54.1 8.2 9.3 31.1 STK31 "SgK396, TDRD8" ENSG00000196335 "Serine/threonine kinase 31" Q9BXU1 7 23710167-23832513 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "testis: 56.0" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 163.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "CACO-2: 20.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023194 Enhanced NA NA "HPA023194: AB_1857590" "unprognostic (4.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.50e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.42e-3)" "unprognostic (2.92e-1)" "unprognostic (1.29e-6)" "unprognostic (7.83e-2)" "unprognostic (9.21e-3)" "unprognostic (1.46e-1)" "unprognostic (3.65e-1)" 0.1 0.0 0.1 0.1 0.7 0.0 0.1 0.8 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.1 56.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 20.1 2.5 0.0 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.8 0.1 0.2 0.0 0.1 0.1 0.1 0.1 3.0 1.4 0.0 0.2 0.1 1.7 0.4 2.5 6.7 4.5 0.0 0.0 0.5 0.0 0.2 16.5 0.0 0.3 0.0 0.6 0.1 0.0 0.3 0.0 0.8 0.2 0.0 1.2 0.0 0.0 12.3 3.1 0.0 0.0 0.0 0.2 1.3 0.4 0.8 2.8 0.0 1.2 0.0 0.0 163.1 32.6 0.1 0.5 0.0 0.4 0.4 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387852 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 19.7;brain: 21.1;retina: 31.9" "Cell type enhanced" "Detected in some" 14 "Early spermatids: 5.0;Melanocytes: 15.1;Muller glia cells: 4.6" "Cancer enhanced" "Detected in many" "melanoma: 11.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.2" "Group enriched" "Detected in some" 5 "RT4: 9.8;SK-MEL-30: 34.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 2.1 19.7 4.8 1.3 7.1 0.4 2.3 21.1 7.7 1.2 1.8 6.2 0.6 1.2 1.6 5.6 1.0 1.3 4.3 1.6 4.9 12.6 6.3 0.6 2.1 0.5 12.1 2.2 5.1 4.2 0.4 8.5 0.7 20.7 2.1 1.1 31.9 1.2 1.8 0.6 2.9 1.1 1.4 12.4 0.8 1.4 2.1 6.9 0.0 15.7 0.5 0.5 4.1 2.1 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.1 3.8 9.8 0.9 0.4 0.0 0.1 34.7 0.1 0.0 0.0 0.1 0.0 0.6 0.4 0.4 1.1 0.2 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 4.8 7.1 21.1 2.3 4.9 12.6 12.1 2.2 20.7 6.9 0.0 1.6 0.0 0.2 1.3 1.2 0.4 0.0 0.0 1.2 1.8 0.0 0.0 1.7 1.2 5.0 0.0 0.0 0.0 2.4 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.4 0.9 0.0 15.1 0.0 0.0 4.6 4.1 0.0 3.9 3.0 0.9 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.6 STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051442-5500998 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.6;lymphoid tissue: 33.6" "Cell type enhanced" "Detected in some" 25 "Distal tubular cells: 14.9;Early spermatids: 83.1;Late spermatids: 31.4;Proximal tubular cells: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive B-cell: 1.3;plasmacytoid DC: 3.5" "Group enriched" "Detected in many" 4 "B-cells: 1.3;dendritic cells: 3.5" "Cell line enhanced" "Detected in some" "GAMG: 11.9;HUVEC TERT2: 11.7;REH: 10.3;U-2197: 18.7;WM-115: 47.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA015820 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Nucleoplasm, Nuclear bodies" Cytosol "HPA015820: AB_1858913" "unprognostic (4.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.08e-2)" "unprognostic (1.35e-1)" "unprognostic (8.12e-3)" "unprognostic (9.96e-2)" "unprognostic (1.64e-4)" "unprognostic (1.27e-1)" "unprognostic (1.27e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.63e-8)" "unprognostic (8.10e-3)" "unprognostic (5.04e-2)" "unprognostic (3.62e-2)" "unprognostic (1.67e-3)" 5.2 0.8 6.0 2.1 4.8 2.3 7.3 1.0 5.8 6.0 2.1 5.2 1.6 1.2 5.7 1.6 2.3 2.5 4.7 0.9 4.5 7.6 23.6 0.5 1.3 2.8 5.3 2.2 1.2 4.9 0.8 0.8 5.1 4.2 2.3 2.2 3.0 2.9 1.9 2.1 3.6 1.6 7.0 3.9 0.6 9.5 7.1 2.9 33.6 2.8 2.1 1.9 4.2 6.1 1.3 3.5 0.0 0.5 0.0 0.0 0.0 0.0 5.8 0.3 0.0 0.2 0.4 0.0 4.0 0.5 2.7 0.1 0.0 0.0 0.0 0.9 8.2 11.9 0.0 0.6 0.0 1.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.1 11.7 0.6 0.0 0.0 1.4 0.0 0.0 0.8 1.7 0.0 0.0 10.3 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 3.5 0.3 0.0 0.0 3.0 0.0 1.2 18.7 0.0 0.4 0.0 0.0 0.0 0.0 47.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 6.0 4.8 1.0 5.8 4.5 7.6 5.3 2.2 4.2 2.9 0.0 0.6 0.0 0.1 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.8 83.1 1.6 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 31.4 1.4 0.9 5.0 0.0 0.0 0.0 0.3 0.0 1.1 13.3 0.0 0.0 0.3 0.9 3.0 0.9 0.0 0.0 0.0 0.0 STK32C "MGC23665, PKE, YANK3" ENSG00000165752 "Serine/threonine kinase 32C" Q86UX6 10 132207492-132331847 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017894 Uncertain NA NA "HPA017894: AB_1857591" "unprognostic (2.11e-1)" "unprognostic (8.40e-2)" "unprognostic (4.80e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.65e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (1.68e-6)" "unprognostic (2.03e-1)" "unprognostic (7.79e-2)" "unprognostic (2.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.31e-6)" "unprognostic (8.65e-2)" "unprognostic (3.20e-1)" "unprognostic (5.05e-2)" "unprognostic (1.36e-1)" 6.8 8.2 23.5 6.4 23.5 6.1 7.1 8.3 31.6 4.1 4.9 6.3 6.0 5.0 4.6 15.5 3.4 9.4 7.8 7.0 17.9 12.8 6.3 4.2 7.3 8.5 9.2 16.1 5.8 7.0 6.2 6.7 4.8 7.7 4.6 4.7 3.2 5.6 5.5 11.3 7.1 4.7 4.9 7.7 10.7 4.8 26.1 8.1 8.7 4.9 3.0 6.1 4.6 3.6 5.5 14.5 25.0 11.2 3.2 4.9 3.6 32.1 21.1 6.5 16.3 9.1 11.6 1.3 6.8 5.3 8.6 11.1 4.7 22.5 7.1 5.1 7.8 10.9 7.4 9.4 2.7 8.4 4.2 15.1 4.1 21.6 22.3 11.5 3.7 15.5 8.7 10.3 7.8 8.9 11.0 7.5 12.1 7.2 5.0 9.2 9.7 4.7 14.2 4.2 5.9 15.4 5.7 4.1 2.2 11.2 5.6 17.0 13.3 4.8 4.5 9.5 4.0 5.2 9.0 5.0 7.1 7.1 8.9 5.3 9.3 1.7 17.7 15.5 3.6 3.4 25.0 10.7 9.2 3.5 11.2 4.5 3.6 2.9 4.0 14.5 5.5 3.6 2.9 1.4 3.2 9.5 8.3 4.9 3.6 23.5 23.5 8.3 31.6 17.9 12.8 9.2 16.1 7.7 8.1 0.0 11.1 5.2 5.5 4.6 8.8 2.9 2.5 14.7 5.7 12.2 11.8 2.8 16.6 5.0 222.3 8.3 2.6 0.0 7.5 2.0 7.3 7.5 15.1 4.9 13.1 35.0 18.4 11.1 20.5 53.0 8.3 18.4 11.8 6.4 5.5 7.3 6.0 4.0 6.3 9.7 14.6 6.5 5.3 31.4 17.2 4.4 1.3 9.2 7.9 6.2 STK33 ENSG00000130413 "Serine/threonine kinase 33" Q9BYT3 11 8391868-8594289 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.4" "Cell type enhanced" "Detected in many" 12 "Ciliated cells: 245.0;Late spermatids: 113.1;Rod photoreceptor cells: 83.4;Spermatocytes: 126.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 7.1;naive B-cell: 4.4" "Lineage enriched" "Detected in many" 5 "B-cells: 7.1" "Cell line enhanced" "Detected in many" "Daudi: 14.0;hTERT-RPE1: 14.2;Karpas-707: 13.1;SCLC-21H: 14.7;U-251 MG: 14.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA015742, HPA056855" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA Nucleoplasm "Nucleoli, Cytosol" "HPA015742: AB_1857592, HPA056855: AB_2683257" "unprognostic (2.57e-2)" "unprognostic (2.80e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (3.57e-1)" "unprognostic (1.40e-1)" "unprognostic (7.28e-2)" "unprognostic (3.85e-4)" "unprognostic (1.23e-1)" "unprognostic (8.06e-2)" "unprognostic (1.33e-3)" "unprognostic (9.46e-2)" "prognostic favorable (4.89e-6)" "unprognostic (2.39e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.90e-2)" 0.9 6.1 4.7 1.6 7.5 1.1 0.6 6.1 4.4 5.4 5.3 6.8 7.7 2.6 9.6 15.3 2.3 30.7 4.5 11.4 6.6 6.1 7.7 0.4 5.3 2.3 4.9 2.7 10.3 4.6 20.4 29.9 0.3 17.7 5.3 1.3 14.8 1.6 8.9 2.6 0.3 2.5 7.0 6.7 1.2 4.4 34.4 4.6 4.5 14.6 1.5 1.8 3.7 1.4 7.1 0.7 0.0 0.0 0.2 1.4 0.3 0.0 2.0 9.7 0.0 0.0 0.0 0.0 1.7 1.9 4.2 3.9 1.1 0.0 14.0 7.3 0.3 5.5 0.0 4.3 1.3 3.7 0.0 11.9 0.0 2.6 3.3 1.6 7.8 0.0 0.4 0.0 0.1 0.0 14.2 0.3 6.9 0.0 13.1 0.1 0.0 0.2 0.0 6.9 0.0 0.0 5.2 1.3 8.8 3.8 0.0 14.7 3.9 0.0 0.0 0.1 2.7 0.0 0.8 0.0 0.0 6.6 0.1 14.8 3.1 12.4 0.2 4.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.1 0.0 1.4 0.0 4.4 0.0 1.1 0.0 0.2 0.0 0.7 0.2 0.3 4.7 7.5 6.1 4.4 6.6 6.1 4.9 2.7 17.7 4.6 17.9 12.6 5.4 1.1 0.0 19.2 34.4 10.2 245.0 47.8 19.2 66.8 0.1 3.3 7.5 72.9 1.3 0.0 0.0 4.4 2.7 0.3 0.2 1.1 0.0 0.2 1.6 8.7 0.0 0.0 113.1 4.0 0.4 0.0 0.0 1.3 30.6 4.5 0.0 15.9 11.9 83.4 0.0 0.2 126.9 25.1 0.0 0.0 0.0 2.9 0.0 STK35 "bA550O8.2, CLIK1" ENSG00000125834 "Serine/threonine kinase 35" Q8TDR2 20 2101611-2177038 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 27.8;testis: 37.6" "Cell type enhanced" "Detected in many" 18 "Early spermatids: 169.1;Horizontal cells: 278.1;Late spermatids: 665.5;Muller glia cells: 155.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026452, HPA051673" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Nucleoplasm, Nuclear bodies" "HPA026452: AB_2671861, HPA051673: AB_2681569" "unprognostic (2.25e-2)" "unprognostic (2.97e-1)" "unprognostic (2.87e-2)" "unprognostic (1.30e-2)" "unprognostic (3.25e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (9.46e-6)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (3.05e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-1)" "unprognostic (4.39e-2)" "unprognostic (1.74e-1)" "unprognostic (4.67e-1)" "unprognostic (1.40e-1)" "unprognostic (4.99e-2)" 5.3 6.0 10.3 3.6 14.3 4.3 5.1 6.1 13.7 3.7 4.3 3.1 2.5 4.2 4.5 3.5 8.0 5.1 4.3 5.2 5.9 4.8 4.4 5.7 4.2 3.3 4.4 7.6 3.9 5.9 5.3 6.5 3.5 4.0 3.8 5.2 27.8 6.1 4.0 3.5 6.3 4.6 4.9 4.5 4.1 4.1 37.6 4.4 1.7 5.4 6.1 4.5 4.1 3.7 1.8 2.0 3.2 1.4 0.8 2.7 1.2 15.1 12.9 10.0 17.2 4.6 6.4 12.2 6.2 7.7 8.3 8.6 16.9 11.8 10.4 5.1 7.7 13.0 22.9 11.8 14.3 9.5 4.1 5.6 9.9 4.5 18.3 5.9 8.9 4.6 5.5 12.6 13.3 11.5 7.7 7.9 10.1 9.5 8.6 5.4 6.7 11.1 12.6 18.6 12.1 8.7 9.7 9.0 6.6 7.5 15.2 16.7 8.1 11.1 19.9 9.9 12.2 9.8 8.9 6.6 14.3 9.8 7.1 9.8 7.6 9.8 7.3 7.6 9.7 6.2 0.0 1.2 0.7 1.9 1.0 2.5 1.7 2.7 1.3 2.0 1.8 2.6 2.2 3.2 0.8 1.4 1.7 1.3 1.2 10.3 14.3 6.1 13.7 5.9 4.8 4.4 7.6 4.0 4.4 11.9 9.8 1.9 4.0 10.3 110.1 11.0 0.0 0.0 6.8 3.5 141.4 6.0 1.7 5.5 169.1 7.7 8.1 0.0 5.9 9.9 6.4 5.1 9.2 7.8 5.0 278.1 5.8 4.3 6.0 665.5 6.4 3.9 6.8 1.8 7.6 155.8 8.1 11.5 5.6 3.1 88.5 0.0 4.6 14.9 11.5 10.3 4.8 6.4 9.9 5.1 STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672026-218702716 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.2" "Cell type enhanced" "Detected in many" 8 "Ciliated cells: 20.1;Cone photoreceptor cells: 35.3;Spermatocytes: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol NA NA Cytosol "HPA027409: AB_10600223, HPA027453: AB_10601893, HPA030058: AB_10601225" "unprognostic (8.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (5.20e-4)" "unprognostic (1.55e-1)" "unprognostic (5.83e-3)" "unprognostic (9.04e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.99e-3)" 4.8 10.0 7.5 4.7 11.4 2.0 6.4 7.9 11.1 9.1 7.4 7.0 11.9 4.1 14.4 13.3 5.0 13.9 9.8 3.3 6.3 3.5 10.1 4.4 6.9 3.9 2.3 6.6 13.6 9.7 12.3 23.2 3.9 7.6 9.5 6.3 9.3 7.3 8.3 3.3 4.6 5.8 7.8 5.5 4.9 7.9 63.2 4.2 3.5 11.4 3.7 5.0 9.3 7.1 1.8 1.6 3.2 1.9 2.2 1.6 1.7 2.5 5.8 12.8 10.9 14.0 10.9 7.9 7.0 5.6 8.9 8.4 7.6 4.2 3.4 9.8 7.3 6.0 5.2 8.8 7.3 7.9 1.4 7.3 3.3 17.6 10.5 6.8 4.6 5.6 11.7 5.5 8.7 6.2 23.8 6.7 4.5 7.6 4.3 7.4 5.9 2.7 5.8 7.7 3.2 3.7 5.1 5.5 3.4 10.9 12.9 10.4 8.9 5.4 8.9 3.6 13.9 9.0 3.8 6.3 12.4 4.6 4.7 4.7 5.5 4.2 1.8 7.7 2.2 5.1 0.0 1.9 3.2 1.5 1.2 0.9 1.8 1.1 1.3 1.6 0.6 1.1 1.6 0.2 2.2 1.4 1.3 1.0 1.7 7.5 11.4 7.9 11.1 6.3 3.5 2.3 6.6 7.6 4.2 8.9 4.6 1.7 1.0 1.0 7.7 2.8 5.1 20.1 1.2 3.5 35.3 1.4 0.0 2.9 11.3 2.1 2.0 0.0 2.2 1.3 1.8 1.3 1.1 4.9 2.3 1.6 2.4 4.3 2.8 4.1 5.5 1.2 0.0 1.0 4.4 5.6 1.9 3.7 4.6 3.3 9.8 6.5 2.1 26.8 8.2 0.9 0.7 1.5 3.8 0.4 STK38 NDR ENSG00000112079 "Serine/threonine kinase 38" Q15208 6 36493892-36547470 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004673, HPA038623, HPA051324" Uncertain Approved Cytosol NA NA Cytosol "CAB004673: AB_425892, HPA038623: AB_10967059, HPA051324: AB_2681442" "unprognostic (3.58e-3)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (6.76e-3)" "unprognostic (8.25e-2)" "unprognostic (1.47e-2)" "unprognostic (2.88e-3)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (1.98e-2)" "unprognostic (3.80e-1)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (3.13e-3)" 19.1 8.4 12.4 39.8 10.0 19.4 32.8 18.8 12.7 16.0 26.3 7.8 14.9 17.0 18.8 16.4 28.1 14.6 18.3 15.3 12.1 7.0 15.0 17.3 21.7 45.9 11.9 6.4 12.3 9.5 7.8 11.0 15.4 9.0 17.0 27.1 11.3 24.8 18.7 14.9 21.8 29.1 28.1 13.1 25.1 16.4 24.4 11.0 34.3 10.6 13.4 28.5 22.4 19.8 10.6 13.1 33.2 30.5 25.8 27.6 22.4 17.8 13.2 14.0 15.1 28.3 21.6 12.2 20.0 16.2 20.8 21.0 10.1 12.3 24.1 15.5 29.7 17.3 19.2 11.6 8.3 24.6 9.8 9.9 17.2 17.2 9.1 14.0 6.5 9.5 14.2 21.9 16.1 10.4 24.0 13.0 12.3 14.0 14.1 29.6 10.7 10.5 17.0 5.8 21.3 11.8 40.8 17.0 6.4 19.7 22.5 16.4 7.8 24.3 11.2 14.0 16.4 12.0 17.2 12.5 16.9 15.0 13.5 12.9 11.8 21.0 17.0 3.8 25.4 16.3 33.2 19.8 15.0 27.6 22.6 21.5 10.6 22.9 24.1 13.1 8.1 20.5 22.3 27.1 25.8 30.5 6.6 21.4 22.4 12.4 10.0 18.8 12.7 12.1 7.0 11.9 6.4 9.0 11.0 17.9 16.5 10.8 8.5 11.9 2.5 15.1 22.9 37.5 50.0 7.0 0.0 11.8 1.7 16.1 5.8 12.4 32.4 0.0 11.2 15.4 19.9 11.5 12.7 13.6 11.7 4.8 13.8 11.1 28.5 4.1 25.0 31.7 16.9 9.0 22.9 6.1 19.6 25.9 28.3 13.6 8.5 12.9 13.7 23.6 9.6 18.4 12.8 23.6 22.1 22.5 STK38L "KIAA0965, NDR2" ENSG00000211455 "Serine/threonine kinase 38 like" Q9Y2H1 12 27243968-27325959 "Enzymes, Predicted intracellular proteins" "Actin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 19.3;granulocytes: 32.2;monocytes: 13.0" "Cell line enhanced" "Detected in all" "HDLM-2: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038623, HPA051324" Approved Approved Cytosol NA NA Cytosol "HPA038623: AB_10967059, HPA051324: AB_2681442" "unprognostic (2.14e-2)" "unprognostic (1.01e-1)" "unprognostic (9.94e-2)" "unprognostic (2.43e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (4.68e-2)" "unprognostic (5.56e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (5.82e-4)" "unprognostic (1.16e-1)" "unprognostic (3.41e-2)" "unprognostic (1.09e-1)" "unprognostic (1.95e-1)" "unprognostic (5.05e-2)" "unprognostic (1.05e-2)" 21.2 8.4 11.0 14.6 10.9 10.9 27.2 9.6 14.6 13.0 26.3 5.7 9.7 8.4 23.9 18.2 16.8 14.8 18.2 30.2 10.9 7.8 8.9 8.5 10.8 7.8 11.1 11.8 9.6 8.9 30.2 15.2 10.6 11.9 15.3 15.0 6.8 14.0 10.9 9.1 10.8 14.6 52.3 17.0 7.6 15.6 7.5 10.1 10.0 8.8 10.5 9.8 21.9 22.7 4.5 19.3 32.2 13.0 4.0 4.0 5.3 4.2 5.8 15.1 6.7 6.9 4.7 11.2 2.7 4.0 1.7 2.5 7.3 3.2 9.9 6.5 2.4 5.2 7.9 6.8 4.7 2.7 57.8 5.6 6.1 7.0 3.6 5.8 15.0 7.1 5.7 4.9 6.4 8.2 11.2 13.9 12.8 7.4 7.8 3.5 3.0 9.8 16.3 17.9 11.2 8.8 3.7 17.6 7.6 2.5 8.1 2.4 8.1 12.2 7.5 4.7 15.4 3.7 5.1 5.4 6.0 5.3 8.6 7.4 2.8 2.8 10.4 3.0 7.0 2.4 6.0 13.0 22.9 4.0 11.1 2.8 4.5 3.1 3.9 19.3 3.4 3.8 3.1 32.2 4.0 8.1 8.2 4.0 5.3 11.0 10.9 9.6 14.6 10.9 7.8 11.1 11.8 11.9 10.1 17.9 14.4 9.8 27.4 31.5 11.3 44.5 10.2 9.4 20.5 8.7 2.0 10.0 8.3 41.2 13.6 21.5 19.7 0.0 35.8 7.9 16.0 21.3 16.3 13.0 27.6 9.5 18.5 18.4 33.1 2.3 6.1 48.1 20.3 45.1 27.7 7.5 51.1 31.7 11.3 10.5 6.4 19.4 50.7 6.5 12.1 28.0 23.2 12.5 20.5 39.1 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168248141 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Cell type enhanced" "Detected in many" 5 "Glandular cells: 65.7;Urothelial cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: AB_2684616, HPA062802: AB_2684870" "prognostic favorable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 6.2 2.1 8.4 4.6 11.0 1.3 3.5 9.3 14.1 4.3 9.1 8.3 1.7 10.5 2.3 4.7 14.1 1.9 5.9 7.6 9.8 7.4 2.9 0.8 2.4 7.3 12.3 9.7 3.2 9.9 5.0 8.2 1.2 14.2 9.9 11.7 7.1 22.8 3.8 2.2 3.4 6.1 4.3 19.0 2.5 11.2 35.5 5.5 7.2 2.2 1.8 8.0 5.6 5.3 0.7 1.0 0.0 0.7 1.9 3.4 0.5 6.7 4.1 15.5 4.9 9.5 14.1 1.5 17.0 12.5 11.4 10.6 0.0 22.0 18.7 4.7 11.0 9.9 17.7 9.9 12.4 14.3 5.9 6.1 7.7 4.5 13.8 17.8 10.4 0.8 9.7 17.7 13.5 14.1 13.8 7.7 14.7 0.1 0.0 23.9 3.9 18.1 3.7 10.7 14.0 8.6 25.8 6.1 1.5 8.6 16.8 22.9 9.7 5.9 0.9 6.9 7.7 3.1 7.6 7.3 13.8 4.3 9.7 11.1 0.0 0.0 15.0 10.5 9.3 9.3 0.0 0.7 0.0 2.5 0.4 1.3 0.7 1.9 3.4 1.0 0.7 0.4 2.0 0.0 1.9 0.3 0.3 3.3 0.5 8.4 11.0 9.3 14.1 9.8 7.4 12.3 9.7 14.2 5.5 3.0 12.3 0.8 21.2 3.4 13.8 25.8 22.9 6.7 7.9 5.2 15.7 0.1 18.3 9.7 21.3 3.5 23.2 0.0 19.9 0.0 7.3 65.7 0.0 0.0 3.5 19.1 21.9 3.1 5.1 13.5 9.5 5.2 16.9 1.0 13.9 26.9 26.4 17.3 10.6 3.8 25.3 6.5 7.2 19.9 7.7 3.9 0.2 15.2 20.4 55.5 STK4 "KRS2, MST1, YSK3" ENSG00000101109 "Serine/threonine kinase 4" Q13043 20 44966474-45079959 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "monocytes: 469.7;T-cells: 231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004038, HPA015270" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB004038: AB_2144632, HPA015270: AB_1854150" "unprognostic (2.77e-1)" "unprognostic (1.10e-1)" "unprognostic (8.83e-2)" "unprognostic (8.49e-3)" "unprognostic (2.95e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (1.70e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.96e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.28e-1)" "unprognostic (5.70e-2)" "unprognostic (3.96e-1)" "unprognostic (1.18e-2)" 9.5 8.8 10.4 24.5 11.5 39.5 8.1 7.5 13.4 7.8 8.6 10.3 5.4 8.1 9.3 6.5 8.9 7.3 9.4 6.1 9.3 8.8 6.3 7.4 18.8 30.6 10.5 9.1 8.3 6.4 5.9 9.3 8.2 7.7 7.5 10.6 7.4 9.3 8.7 4.2 11.4 16.1 8.2 12.0 29.1 9.6 7.4 9.6 32.3 8.0 4.9 36.6 11.5 8.7 10.8 6.9 40.6 13.3 10.3 14.5 7.9 11.8 8.0 10.3 7.3 6.3 7.9 7.1 10.5 16.0 17.7 16.1 22.7 6.5 28.9 9.1 7.4 14.9 12.6 10.8 14.0 22.8 12.9 5.7 21.1 11.7 16.0 11.1 27.1 30.0 6.4 11.6 16.6 18.2 8.9 6.5 19.6 9.7 16.7 8.9 9.3 20.2 18.3 6.2 7.7 5.5 13.1 11.3 13.4 6.5 8.1 4.9 6.0 15.5 9.0 11.8 8.2 8.2 17.1 8.3 13.4 13.0 15.4 12.0 21.8 17.1 32.3 13.1 13.0 9.8 24.4 7.6 20.5 14.5 7.7 14.4 10.3 13.8 13.3 6.9 10.8 14.3 11.9 40.6 10.3 13.3 3.9 13.3 7.9 10.4 11.5 7.5 13.4 9.3 8.8 10.5 9.1 7.7 9.6 14.9 24.0 181.6 40.4 49.5 24.2 7.0 15.3 16.0 18.2 40.1 49.1 20.3 8.3 14.1 4.8 32.3 20.5 0.0 15.3 21.4 24.3 25.1 129.5 19.1 53.0 41.3 24.6 22.7 103.3 3.6 21.0 108.8 126.5 469.7 17.4 20.3 16.0 25.9 15.9 10.9 64.0 12.9 30.2 36.4 43.8 46.3 16.2 231.2 17.4 36.3 STK40 "MGC4796, SgK495" ENSG00000196182 "Serine/threonine kinase 40" Q8N2I9 1 36339624-36385896 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Late spermatids: 181.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "neutrophil: 19.2" "Group enriched" "Detected in all" 5 "granulocytes: 19.2;monocytes: 8.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008026 Uncertain Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA008026: AB_1857603" "unprognostic (3.32e-1)" "unprognostic (3.00e-1)" "unprognostic (6.47e-2)" "unprognostic (4.55e-1)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (2.69e-3)" "unprognostic (6.09e-2)" "unprognostic (2.09e-1)" "unprognostic (5.96e-2)" "prognostic favorable (5.59e-4)" "unprognostic (1.19e-1)" "unprognostic (2.75e-2)" "unprognostic (7.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" 22.9 7.2 9.8 15.3 9.4 9.2 26.5 8.9 11.1 10.2 19.1 7.4 16.7 9.4 11.8 12.2 22.3 11.3 18.2 25.6 10.0 7.1 14.3 23.5 16.6 15.4 13.1 7.4 22.2 34.4 9.2 14.7 19.2 12.1 15.7 9.1 9.0 25.1 17.7 53.9 17.2 10.8 26.0 10.3 17.2 17.0 32.0 8.9 9.2 14.6 20.7 16.6 19.5 26.6 2.4 2.7 19.2 8.5 1.6 2.9 2.4 7.1 3.1 15.7 16.3 11.1 6.5 8.8 7.2 9.8 8.8 9.5 17.2 10.3 30.2 5.9 6.7 9.3 7.2 14.3 3.1 6.5 13.1 11.2 19.7 2.9 21.9 11.1 11.5 26.3 5.8 11.9 6.7 3.5 4.7 5.5 23.4 24.2 11.0 5.4 11.2 11.9 15.2 10.1 12.9 4.3 13.7 10.7 20.0 5.5 8.0 19.3 9.8 5.5 8.7 24.1 10.4 5.9 13.6 9.1 5.5 11.6 16.2 15.9 11.5 6.4 25.5 28.9 10.1 18.1 1.0 3.0 4.9 2.6 6.7 2.9 2.3 1.7 1.7 2.7 2.4 1.0 1.5 19.2 1.6 8.5 2.6 1.0 2.4 9.8 9.4 8.9 11.1 10.0 7.1 13.1 7.4 12.1 8.9 11.9 18.3 19.8 48.5 54.5 12.0 21.1 2.5 6.7 7.9 10.4 3.9 4.7 14.9 14.5 92.4 11.0 27.7 0.0 27.1 8.3 15.3 55.1 12.7 19.5 21.4 9.5 22.4 12.9 20.3 181.6 21.3 21.3 28.7 14.4 12.9 4.5 23.4 14.4 31.5 10.5 9.5 25.8 30.9 12.6 8.7 65.9 47.8 14.6 10.8 43.7 STKLD1 "C9orf96, MGC43306, SGK071" ENSG00000198870 "Serine/threonine kinase like domain containing 1" Q8NE28 9 133376367-133406096 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 16.2" "Cell type enhanced" "Detected in many" 16 "Early spermatids: 27.3;Late spermatids: 39.6;Spermatocytes: 15.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029902 Uncertain NA NA "HPA029902: AB_10603554" "unprognostic (6.65e-2)" "unprognostic (9.43e-3)" "unprognostic (7.54e-4)" "unprognostic (8.15e-2)" "unprognostic (9.51e-2)" "unprognostic (1.39e-2)" "unprognostic (1.99e-2)" "unprognostic (1.41e-3)" "unprognostic (6.05e-2)" "unprognostic (2.94e-4)" "unprognostic (1.92e-4)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "unprognostic (4.69e-2)" "unprognostic (3.65e-1)" "unprognostic (5.86e-2)" "unprognostic (4.52e-2)" 0.4 0.4 0.4 0.2 1.4 0.5 0.4 0.7 2.2 0.4 0.3 2.2 1.3 0.5 0.9 2.1 0.3 0.6 0.5 0.3 0.8 0.3 0.3 0.4 0.3 0.8 0.5 1.3 0.8 0.4 0.1 0.3 0.5 1.5 0.5 0.1 0.8 0.6 0.4 0.6 0.8 0.5 0.3 0.5 0.4 0.4 16.2 0.7 0.0 0.3 0.0 0.3 0.3 0.3 0.6 0.4 0.0 0.2 0.2 0.6 0.0 0.0 0.6 0.4 0.7 0.5 0.5 1.1 0.2 0.0 0.1 0.2 0.9 0.3 0.3 0.2 0.0 0.6 0.6 0.1 0.0 0.0 0.4 0.8 0.7 0.9 0.5 0.3 0.5 0.4 0.4 0.1 0.0 0.1 0.4 0.0 1.5 0.8 1.0 0.0 0.2 0.6 0.8 0.3 0.6 1.0 0.3 0.3 0.8 0.1 0.1 1.0 1.0 0.3 0.9 2.2 0.3 1.3 0.3 0.6 1.0 0.6 0.9 0.1 2.2 2.2 0.6 0.4 0.4 0.3 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.4 0.2 0.1 0.6 0.6 0.2 0.0 0.2 0.1 0.4 0.0 0.0 0.4 1.4 0.7 2.2 0.8 0.3 0.5 1.3 1.5 0.7 0.0 0.0 0.0 1.1 0.0 3.3 1.2 2.5 0.0 1.2 0.0 2.0 3.6 8.3 0.4 27.3 0.5 0.0 0.0 1.0 0.6 0.3 0.7 0.0 1.0 0.8 1.6 0.0 0.0 0.3 39.6 2.0 0.0 0.0 0.0 0.3 1.2 0.3 0.0 1.8 1.7 2.3 0.0 0.2 15.1 3.4 0.0 2.7 0.0 0.7 0.6 STRADA "LYK5, NY-BR-96, Stlk, STRAD" ENSG00000266173 "STE20-related kinase adaptor alpha" Q7RTN6 17 63682336-63741986 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 13 "monocytes: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031637 Approved Supported Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA031637: AB_10601718" "unprognostic (1.59e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-3)" "unprognostic (5.52e-2)" "unprognostic (8.91e-2)" "unprognostic (7.56e-5)" "unprognostic (6.79e-4)" "unprognostic (3.68e-2)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "prognostic favorable (5.34e-5)" "unprognostic (7.29e-2)" "prognostic unfavorable (6.08e-7)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "prognostic favorable (6.43e-4)" 13.3 17.7 19.4 14.6 23.7 17.5 13.0 25.0 28.4 15.2 13.2 27.1 8.7 9.5 16.1 20.6 14.3 20.9 14.5 15.1 18.9 20.2 14.7 13.0 13.9 19.6 20.9 21.7 18.5 12.5 21.9 17.5 14.4 26.0 13.8 13.1 22.2 12.6 16.7 10.3 20.1 12.0 19.1 19.4 20.7 12.6 55.4 21.4 16.2 13.3 8.9 21.3 12.9 12.8 11.2 16.2 18.6 10.0 15.6 11.7 7.5 7.2 21.7 18.9 19.0 18.6 13.9 7.4 13.8 12.7 19.9 17.8 5.7 8.4 11.0 8.6 11.7 9.9 6.0 12.5 13.3 19.8 12.2 12.1 21.8 15.2 13.4 13.2 20.6 15.7 14.5 11.5 22.6 13.1 13.3 22.0 17.3 13.9 11.8 18.8 13.4 24.2 14.1 9.4 6.2 12.4 15.8 30.1 13.5 17.8 14.3 20.7 23.2 9.4 15.5 15.1 20.4 11.4 15.0 17.6 19.0 13.5 15.3 11.4 11.8 12.6 13.9 14.2 12.5 14.9 18.6 9.5 8.6 10.5 7.1 9.7 11.2 9.7 11.7 16.2 9.0 9.6 8.5 11.4 15.6 10.0 13.7 7.2 7.5 19.4 23.7 25.0 28.4 18.9 20.2 20.9 21.7 26.0 21.4 8.9 8.2 2.2 0.1 0.0 1.5 0.5 0.0 2.7 4.5 8.7 0.0 1.5 0.0 6.0 1.1 0.6 1.6 0.0 2.5 0.7 0.7 0.3 2.3 0.0 1.3 1.6 0.0 0.6 0.3 1.6 0.6 4.6 0.0 29.7 1.6 1.0 3.9 2.5 1.4 0.6 3.7 0.0 1.4 2.7 0.5 0.4 2.1 1.0 1.9 0.1 STRADB "ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK" ENSG00000082146 "STE20-related kinase adaptor beta" Q9C0K7 2 201387858-201480846 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 8 "Erythroid cells: 186.9;Proximal tubular cells: 173.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026549, HPA028520" Approved Uncertain Aggresome,Cytosol NA NA Cytosol Aggresome "HPA026549: AB_1844779, HPA028520: AB_10604100" "unprognostic (6.34e-2)" "unprognostic (2.48e-1)" "unprognostic (2.63e-1)" "unprognostic (3.56e-3)" "unprognostic (4.04e-2)" "unprognostic (7.64e-2)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (2.63e-3)" "unprognostic (2.65e-2)" "unprognostic (6.21e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.08e-1)" "unprognostic (7.83e-2)" "prognostic favorable (4.45e-4)" "unprognostic (4.93e-2)" 13.8 28.6 13.8 7.9 11.7 32.7 9.2 8.8 13.5 6.4 13.7 16.9 4.9 18.8 10.3 9.5 8.9 5.7 7.9 15.2 15.3 11.5 35.2 50.5 7.2 10.1 15.8 11.0 7.8 9.1 3.9 14.1 11.6 12.7 7.1 15.9 10.1 7.1 7.7 48.3 4.4 21.3 7.4 21.0 7.3 4.7 7.8 9.4 8.3 9.7 7.8 7.7 6.2 6.2 24.1 10.4 9.7 8.6 16.3 10.4 9.6 3.9 6.8 11.9 15.2 19.4 24.6 8.4 8.0 14.0 11.2 17.0 9.0 3.8 0.0 5.3 12.7 13.8 4.0 11.5 7.6 20.3 4.6 9.4 4.8 3.2 19.9 14.7 5.6 5.4 20.8 6.9 14.3 12.8 20.9 8.4 9.2 10.2 1.7 60.3 2.1 5.1 9.8 16.0 3.7 7.0 7.0 4.6 2.9 9.5 3.2 2.0 9.8 5.5 4.2 23.6 22.7 2.2 10.8 8.1 6.9 5.3 8.7 6.1 6.7 11.8 1.8 11.6 2.5 6.4 3.4 8.0 9.7 6.0 8.6 5.4 16.7 8.0 8.6 10.4 24.1 10.4 10.3 1.6 16.3 7.5 4.6 9.5 9.6 13.8 11.7 8.8 13.5 15.3 11.5 15.8 11.0 12.7 9.4 8.9 3.4 20.8 6.4 1.9 10.4 29.0 15.3 5.3 3.4 14.0 78.5 41.3 33.2 9.4 3.0 4.9 62.6 186.9 13.6 22.9 10.8 10.0 5.7 77.9 16.8 11.1 16.3 3.1 17.8 5.8 10.0 8.3 15.1 17.2 23.2 13.5 11.0 26.2 3.5 173.8 17.1 6.5 4.1 27.0 44.7 1.3 23.3 9.6 22.7 7.7 STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618939-10674318 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8;stomach 1: 16.0" "Cell type enhanced" "Detected in some" 8 "Ciliated cells: 8.1;Enterocytes: 12.5;Mucus-secreting cells: 8.3;Paneth cells: 9.5;Undifferentiated cells: 6.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.5;HDLM-2: 10.9;HMC-1: 12.1;HUVEC TERT2: 16.6;TIME: 15.4" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA040468: AB_2676998, HPA048569: AB_2680446" "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" 0.6 0.3 2.6 2.3 10.6 1.0 3.8 0.1 13.4 2.2 14.4 0.7 0.5 2.1 0.5 1.1 8.9 1.9 6.2 0.1 1.8 1.6 0.5 0.3 1.2 2.4 1.8 4.2 0.4 0.3 0.0 8.4 3.4 2.1 10.6 15.8 0.0 7.8 2.6 0.2 2.6 10.3 0.6 0.6 1.0 16.0 0.3 0.7 0.0 0.4 0.6 2.8 4.3 3.6 0.0 0.0 0.4 0.0 12.5 1.9 0.2 3.0 0.1 0.0 0.4 0.0 0.0 0.9 4.9 0.5 2.3 2.2 1.6 18.5 0.2 3.1 1.2 2.9 0.8 1.0 5.1 4.9 10.9 0.3 0.7 1.3 0.1 0.0 1.4 12.1 0.2 0.3 3.4 0.2 0.4 16.6 0.1 0.2 0.2 5.3 1.7 0.1 0.8 2.7 7.5 1.3 0.0 1.4 0.2 1.6 9.5 0.6 0.0 2.8 2.9 0.0 4.5 2.3 0.3 15.4 0.6 2.6 0.3 0.6 0.0 0.6 0.1 2.1 0.1 3.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.3 0.4 12.5 0.0 0.0 0.0 0.2 2.6 10.6 0.1 13.4 1.8 1.6 1.8 4.2 2.1 0.7 0.0 2.1 0.0 0.6 0.2 0.4 0.4 2.5 8.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 12.5 0.0 0.2 0.5 0.0 5.9 1.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 3.6 9.5 0.0 0.0 0.3 0.0 0.1 0.0 0.9 0.9 0.2 0.7 6.8 4.8 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in many" 6 "B-cells: 53.8;Hofbauer cells: 63.0;Kupffer cells: 79.3;Macrophages: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 21.4;eosinophil: 23.3;intermediate monocyte: 19.0;memory B-cell: 23.1;myeloid DC: 24.9;naive B-cell: 17.5;neutrophil: 32.8;NK-cell: 8.7;non-classical monocyte: 16.4;plasmacytoid DC: 18.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 39.4;HEL: 22.7;HL-60: 31.3;HMC-1: 20.9;REH: 26.2;THP-1: 24.1;U-698: 18.6;U-937: 22.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 1000000 "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.2 3.3 6.0 38.1 9.6 18.2 6.7 1.1 4.5 3.7 10.3 6.7 1.5 12.3 2.3 6.7 16.2 6.9 6.6 5.5 7.2 3.2 8.6 2.5 13.7 36.4 9.1 2.5 2.1 8.9 25.9 3.1 5.0 6.1 4.1 8.3 2.8 8.9 1.8 1.4 8.3 22.2 3.5 11.3 38.5 7.4 5.5 7.9 30.5 18.1 7.8 32.2 8.6 7.5 23.1 24.9 32.8 21.4 8.7 0.1 10.2 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 39.4 1.1 0.0 1.3 6.1 0.8 3.2 0.0 0.0 5.4 22.7 0.0 0.0 0.0 31.3 20.9 0.0 4.5 0.0 0.4 0.0 0.0 4.9 0.6 3.2 0.0 4.8 0.0 13.7 0.2 14.8 0.0 26.2 0.0 10.8 0.8 5.9 2.1 1.8 0.0 2.8 0.0 0.1 2.5 24.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.6 0.0 22.1 0.0 1.4 21.4 23.3 0.1 19.0 0.1 23.1 0.0 0.0 24.9 17.5 0.0 0.0 32.8 8.7 16.4 18.5 0.0 10.2 6.0 9.6 1.1 4.5 7.2 3.2 9.1 2.5 6.1 7.9 11.9 22.7 53.8 3.7 3.1 0.9 1.6 12.7 12.0 17.0 14.0 0.0 1.2 13.3 12.6 5.5 1.1 18.4 0.0 10.9 1.3 1.1 1.8 40.6 0.9 63.0 0.0 9.9 4.9 79.3 4.7 0.6 66.0 11.8 24.4 23.8 0.0 15.3 28.1 0.0 0.3 0.1 6.5 1.0 0.7 0.7 5.0 1.1 5.3 24.7 6.5 TAOK1 "FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1" ENSG00000160551 "TAO kinase 1" Q7L7X3 17 29390464-29551904 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007669 Approved Uncertain Vesicles NA NA 13000 Vesicles "HPA007669: AB_1080201" "unprognostic (1.46e-1)" "unprognostic (7.15e-3)" "unprognostic (2.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.28e-2)" "unprognostic (4.31e-2)" "unprognostic (1.15e-1)" "unprognostic (6.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.85e-2)" "unprognostic (5.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" 17.2 11.5 19.1 11.9 25.0 12.7 13.3 20.1 24.4 15.8 11.9 22.2 7.9 7.1 14.9 10.8 12.7 11.0 11.6 15.3 18.7 15.5 13.6 10.6 13.2 11.1 30.0 17.6 13.5 9.3 31.7 13.7 14.3 21.8 12.0 10.7 10.9 11.1 13.3 15.0 13.8 9.8 17.7 21.0 13.0 10.8 14.3 23.5 11.7 17.7 6.0 11.2 14.5 17.1 2.4 4.8 5.5 2.1 1.4 3.0 0.9 13.7 24.5 19.3 8.2 14.4 18.3 8.1 13.0 13.9 11.9 12.6 13.2 4.8 8.5 12.7 21.1 12.8 10.8 17.6 9.0 21.6 17.8 13.0 13.6 14.1 7.0 10.5 15.0 12.6 12.0 11.6 17.6 18.1 12.6 16.3 8.7 13.9 7.8 15.6 9.2 11.8 5.6 8.2 7.6 6.3 10.9 27.2 5.9 11.3 19.9 10.7 13.1 22.3 20.9 13.4 20.4 15.1 13.9 23.6 18.3 14.9 16.0 18.2 7.2 15.4 9.9 13.4 9.4 16.5 1.7 1.9 1.5 2.0 2.1 1.6 1.6 2.0 2.4 1.7 2.4 3.0 2.2 5.5 1.4 1.9 4.8 1.2 0.9 19.1 25.0 20.1 22.7 18.7 15.5 30.0 17.6 21.8 23.5 44.7 47.4 18.4 23.0 39.5 53.4 78.7 30.6 24.1 38.7 43.6 92.3 15.2 13.3 23.9 10.7 41.3 21.4 0.0 20.9 13.5 47.9 34.5 27.7 23.6 25.9 49.3 36.1 51.5 65.2 12.5 36.8 44.8 38.8 23.4 20.1 35.6 30.2 21.2 50.9 15.9 48.3 25.8 36.8 55.4 33.6 40.1 31.5 19.8 18.0 38.2 TAOK2 "KIAA0881, MAP3K17, PSK, PSK1, TAO1, TAO2" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973641-29992261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Ito cells: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Nucleoplasm, Cytosol" Nucleoli "HPA010650: AB_1080204" "unprognostic (7.30e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.51e-4)" "prognostic favorable (3.87e-5)" "unprognostic (8.46e-2)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-1)" "prognostic favorable (4.78e-4)" "unprognostic (3.85e-3)" "prognostic favorable (3.66e-4)" "unprognostic (7.42e-3)" "unprognostic (3.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.37e-1)" 27.8 24.1 26.2 15.1 26.7 12.3 17.7 29.2 30.6 13.5 13.6 21.5 11.8 18.5 16.8 13.0 12.4 14.1 15.1 17.6 25.0 18.2 13.9 10.4 23.0 14.4 22.1 22.7 15.8 16.3 26.2 18.7 22.5 20.7 13.6 9.6 15.0 17.1 15.9 22.8 20.0 19.3 14.8 14.9 26.3 16.0 21.2 20.2 14.0 15.9 9.8 11.5 12.8 18.0 2.6 3.3 4.8 2.8 2.0 3.2 2.0 11.2 21.5 11.8 18.6 13.9 9.3 18.1 20.7 11.1 14.0 13.1 17.2 15.1 12.2 17.6 14.9 9.4 17.6 10.7 10.4 7.6 18.9 22.7 13.1 21.7 17.2 10.1 12.9 25.3 10.9 9.1 14.9 6.0 9.8 23.4 11.7 11.8 12.4 13.3 20.8 15.0 18.3 11.4 8.4 14.5 27.7 17.1 11.3 8.8 10.6 13.9 11.2 11.8 15.8 6.2 7.9 19.8 14.6 32.6 24.2 11.2 17.1 11.9 18.1 11.6 11.5 14.8 14.8 17.6 1.3 2.8 1.5 2.9 2.7 3.1 2.0 2.9 2.6 1.8 2.6 1.6 1.4 4.8 2.0 1.4 3.3 3.2 2.0 26.2 26.7 29.2 30.6 25.0 18.2 22.1 22.7 20.7 20.2 8.9 11.5 2.2 4.2 9.5 13.3 8.1 5.1 4.0 7.9 8.7 37.3 6.7 1.7 7.6 3.1 27.6 23.3 0.0 10.2 4.8 9.3 5.8 3.5 9.7 8.4 9.5 12.6 44.2 12.4 2.1 11.5 5.5 6.8 4.6 14.9 8.7 12.7 14.2 12.0 6.4 19.2 6.5 7.6 21.1 17.2 8.4 10.1 9.2 13.3 5.7 TAOK3 "DPK, JIK, MAP3K18" ENSG00000135090 "TAO kinase 3" Q9H2K8 12 118149801-118372945 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" 5 "Rod photoreceptor cells: 324.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017160 Approved Uncertain Mitochondria NA NA Mitochondria "HPA017160: AB_1851994" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "unprognostic (7.38e-2)" "unprognostic (2.76e-2)" "unprognostic (8.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.08e-2)" "unprognostic (4.14e-3)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" 14.6 16.2 31.9 24.1 31.0 30.8 14.6 44.3 33.5 11.6 21.2 17.2 10.3 23.1 15.2 11.4 16.0 9.8 16.9 15.1 27.8 31.7 14.0 15.3 19.4 26.3 25.7 20.8 17.5 10.9 20.2 23.6 11.9 20.7 25.6 21.3 12.0 13.6 14.6 18.5 17.0 31.6 15.3 23.7 24.2 20.9 8.9 28.6 28.3 18.1 9.9 26.9 18.5 18.3 20.9 22.4 38.2 37.8 36.4 27.8 17.1 8.3 5.8 4.3 3.8 10.7 13.1 4.9 8.8 10.0 5.1 6.7 2.9 13.0 25.6 2.9 11.7 7.4 7.6 3.7 7.8 8.0 9.2 3.2 30.2 2.9 3.8 12.5 30.9 42.6 8.8 9.4 16.1 23.7 10.8 16.3 15.3 17.5 3.0 9.3 5.9 16.3 20.3 1.7 3.9 3.1 9.5 5.9 2.7 4.8 14.5 0.8 4.3 8.1 3.7 11.2 2.0 7.6 23.2 25.3 8.8 1.5 8.2 7.5 2.9 2.8 20.3 12.5 21.4 11.8 38.2 17.0 37.6 27.8 23.3 26.2 20.9 21.2 24.1 22.4 19.3 18.8 24.5 37.7 36.4 37.8 20.9 19.3 17.1 31.9 31.0 44.3 33.5 27.8 31.7 25.7 20.8 20.7 28.6 32.8 78.2 81.8 42.2 31.3 72.1 47.4 63.7 6.7 30.7 43.6 200.3 29.7 59.7 35.4 11.4 29.2 94.6 23.3 52.0 83.1 34.9 47.7 159.8 52.0 71.7 38.1 24.1 26.4 84.7 8.2 35.9 117.0 33.7 141.5 60.6 40.4 64.9 98.2 44.9 27.2 324.3 45.3 40.5 20.5 22.8 27.5 36.6 86.3 58.2 47.4 TBCK "HSPC302, MGC16169" ENSG00000145348 "TBC1 domain containing kinase" Q8TEA7 4 106041599-106321495 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 25.3;BJ hTERT+ SV40 Large T+ RasG12V: 44.5;HBF TERT88: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039951, HPA051611" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Nucleoplasm, Nucleoli fibrillar center" "HPA039951: AB_10795300, HPA051611: AB_2681550" "unprognostic (1.65e-1)" "unprognostic (2.60e-2)" "unprognostic (8.47e-2)" "unprognostic (1.12e-1)" "unprognostic (8.06e-2)" "unprognostic (1.13e-3)" "unprognostic (1.55e-1)" "unprognostic (3.81e-1)" "unprognostic (8.68e-2)" "unprognostic (1.85e-1)" "unprognostic (3.67e-2)" "unprognostic (1.80e-1)" "prognostic favorable (3.20e-4)" "unprognostic (8.17e-3)" "unprognostic (1.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.29e-1)" 12.8 19.0 14.2 7.6 15.2 3.4 10.0 16.3 15.2 13.5 8.3 10.0 11.0 4.4 10.9 14.9 10.6 13.0 13.2 9.3 12.1 11.1 17.8 10.5 9.6 6.9 15.0 8.5 17.5 8.2 12.6 24.2 13.7 12.1 11.9 9.1 9.0 9.1 14.6 4.2 8.5 7.2 13.3 10.3 8.5 8.1 12.0 13.8 18.5 13.9 4.6 8.9 14.5 10.7 10.7 6.3 11.9 6.8 5.9 8.4 4.2 0.9 2.5 5.2 1.9 19.6 12.3 0.9 3.9 6.3 25.3 44.5 4.5 3.9 1.7 5.9 13.2 3.7 2.3 3.5 4.8 30.4 2.4 1.0 5.4 2.1 4.7 5.1 2.2 3.2 11.4 4.0 2.3 4.0 11.1 6.6 3.2 4.2 2.1 7.7 3.4 2.8 2.1 1.2 6.6 1.8 2.1 3.2 3.6 6.6 4.5 2.8 2.2 3.4 2.4 3.4 7.3 3.4 4.9 3.7 4.5 2.2 1.0 1.9 1.0 2.8 3.7 6.2 3.3 2.3 11.9 6.4 6.3 6.2 6.8 7.2 6.2 6.8 8.4 6.3 10.7 7.4 6.7 0.5 5.9 4.6 6.1 6.7 4.2 14.2 15.2 16.3 15.2 12.1 11.1 15.0 8.5 12.1 13.8 17.9 28.0 8.9 5.8 2.1 19.0 6.7 5.1 14.7 20.5 14.0 19.6 9.6 3.3 3.8 35.4 8.2 3.8 0.0 0.8 5.5 7.0 4.2 10.5 4.4 5.8 11.1 5.2 9.8 4.7 28.9 10.3 4.3 5.0 2.8 6.4 10.1 2.1 5.8 12.0 6.9 15.8 0.0 3.8 10.4 8.2 2.0 6.2 6.9 5.5 4.2 TBK1 NAK ENSG00000183735 "TANK binding kinase 1" Q9UHD2 12 64451880-64502108 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease mutation, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045797, HPA060211" Uncertain Enhanced Nucleoplasm,Vesicles NA NA Nucleoplasm Vesicles "HPA045797: AB_2679457, HPA060211: AB_2684222" "unprognostic (4.73e-2)" "unprognostic (8.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.48e-4)" "unprognostic (1.69e-1)" "unprognostic (2.54e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (4.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.26e-2)" "unprognostic (9.56e-3)" 19.1 23.3 13.7 16.8 17.1 32.3 19.1 17.8 20.5 14.9 18.3 10.0 14.1 18.0 17.0 15.1 15.3 13.8 15.6 11.7 14.7 15.6 15.4 20.8 17.8 18.3 20.2 13.6 15.6 11.1 13.1 27.2 40.6 21.1 16.3 12.9 10.1 15.0 18.3 24.8 12.1 21.4 17.2 18.8 24.6 14.5 27.9 16.9 3.4 13.3 12.6 16.7 18.4 19.6 9.7 8.2 22.5 11.9 16.3 11.8 5.9 13.4 15.4 8.8 12.8 15.8 16.0 19.4 14.7 21.5 13.9 13.2 8.7 8.2 18.8 12.8 15.9 20.1 12.7 11.3 12.4 16.4 17.3 10.8 20.2 11.2 12.0 17.3 20.6 25.2 12.0 11.3 13.9 13.4 24.1 18.5 7.2 15.4 27.4 17.9 16.4 0.6 16.1 17.6 12.3 9.0 9.6 9.8 18.1 15.1 24.4 7.4 10.7 19.4 20.0 14.3 15.3 20.4 15.0 17.1 12.5 12.1 10.0 14.4 17.4 30.2 18.3 15.8 11.4 16.1 22.5 7.3 16.6 11.0 11.9 11.8 9.7 8.0 11.0 8.2 7.6 2.8 7.1 15.1 16.3 10.6 1.9 9.5 5.9 13.7 17.1 17.8 20.5 14.7 15.6 20.2 13.6 21.1 16.9 17.9 15.6 14.7 23.9 9.7 18.4 10.0 7.6 18.7 19.4 21.0 9.8 24.9 10.0 17.0 24.8 24.1 10.7 0.0 20.6 24.3 13.6 35.1 41.6 14.3 18.1 17.5 16.6 16.5 19.0 20.1 17.8 26.2 13.5 27.9 8.0 13.0 14.3 10.2 19.4 11.6 15.8 25.8 17.8 49.9 12.9 13.0 77.5 25.8 9.3 32.4 TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269864 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 8 "Cholangiocytes: 12.7;granulocytes: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basophil: 13.3;eosinophil: 11.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 13.3" "Cell line enhanced" "Detected in many" "HEL: 10.6;HMC-1: 16.7;U-266/70: 16.7;U-266/84: 11.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" NA NA "Plasma membrane" "HPA005733: AB_1857878, HPA024657: AB_2671637" "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favorable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" 3.9 4.5 0.8 7.2 1.1 9.8 5.1 0.6 2.0 3.4 4.8 0.5 8.4 2.8 3.0 21.6 9.5 3.6 2.1 3.3 0.9 0.9 4.0 5.7 6.4 7.0 1.5 0.3 2.9 2.9 2.6 6.4 2.0 3.2 2.0 2.5 3.0 6.8 4.7 2.1 8.1 6.5 3.0 1.2 6.7 2.2 5.5 0.6 4.4 4.4 5.8 11.1 3.2 6.5 0.9 1.3 13.3 0.6 2.9 0.4 0.3 2.3 0.6 0.0 0.0 0.0 0.0 0.1 0.4 1.8 1.1 2.3 0.0 1.8 1.5 1.7 0.0 0.0 0.5 0.9 0.0 1.5 0.1 0.7 10.6 0.8 0.1 0.0 1.7 16.7 0.0 0.2 1.4 0.0 1.1 0.0 0.5 5.8 0.4 3.3 0.8 1.0 3.8 0.3 1.1 0.7 2.4 2.2 0.0 2.8 0.7 0.0 0.2 0.5 0.3 0.4 0.9 0.6 3.4 0.0 0.0 0.0 2.3 0.0 16.7 11.9 2.1 0.0 2.4 0.1 13.3 0.5 11.0 0.1 0.6 0.3 0.9 0.1 0.4 1.3 0.6 0.4 0.4 0.4 2.9 0.1 0.1 0.0 0.3 0.8 1.1 0.6 2.0 0.9 0.9 1.5 0.3 3.2 0.6 6.0 5.0 0.8 1.5 2.3 0.5 1.6 12.7 0.0 4.5 0.0 0.0 1.3 0.0 1.3 3.9 0.6 2.2 0.0 0.9 0.1 0.9 1.1 18.5 3.2 4.0 0.0 2.9 0.0 4.5 1.7 0.0 2.8 1.7 0.0 1.4 5.0 0.9 0.0 0.4 1.8 2.4 6.5 0.7 0.7 1.1 2.6 0.7 2.5 2.0 1.3 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230175 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease mutation, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Endothelial cells: 58.3;Ito cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in single" "neutrophil: 2.2" "Lineage enhanced" "Detected in single" "granulocytes: 2.2" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 36.5;NTERA-2: 18.2;TIME: 39.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 8300000 "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 28.6 7.8 8.1 4.6 5.9 0.4 17.9 3.4 5.4 10.8 4.7 4.6 3.4 3.2 14.5 5.3 6.7 5.9 9.1 13.0 7.1 6.1 25.4 8.7 27.8 2.9 6.9 3.4 6.1 4.5 3.5 4.0 36.3 6.9 5.4 4.7 12.4 3.4 5.5 7.8 3.0 5.3 10.6 5.3 23.4 4.0 3.7 3.5 0.3 9.7 8.4 2.4 6.4 12.4 0.0 0.1 2.2 0.6 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.2 2.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.0 0.0 0.7 0.0 0.0 0.7 0.0 0.9 0.3 0.0 36.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.8 0.0 0.0 39.6 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 8.1 5.9 3.4 5.4 7.1 6.1 6.9 3.4 6.9 3.5 3.0 2.2 0.0 0.0 1.3 0.0 7.8 0.0 0.0 1.2 1.8 0.0 0.4 0.0 0.0 0.6 58.3 0.0 0.0 0.0 1.5 2.4 0.2 0.0 0.8 0.2 0.0 0.0 110.5 10.4 0.4 0.6 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.2 0.0 0.4 0.0 0.2 1.1 1.1 0.0 0.0 0.0 TESK1 ENSG00000107140 "Testis-specific kinase 1" Q15569 9 35605305-35610041 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (5.17e-2)" "unprognostic (2.82e-1)" "unprognostic (4.96e-3)" "unprognostic (5.18e-2)" "unprognostic (2.04e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (1.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.66e-3)" "unprognostic (1.22e-2)" "unprognostic (2.56e-1)" "unprognostic (5.57e-2)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-3)" 30.9 19.4 13.5 10.8 20.5 5.6 25.4 13.4 26.4 14.3 15.2 15.0 9.7 13.7 15.3 13.4 11.0 12.0 13.0 12.8 13.7 13.1 10.5 10.0 11.5 10.7 14.1 10.3 17.0 16.0 13.1 15.7 12.3 12.6 15.1 8.8 14.2 14.6 21.0 47.2 13.7 12.7 16.9 7.3 11.0 12.9 28.4 12.9 9.2 13.0 12.3 9.0 16.6 20.9 1.0 2.3 0.3 1.8 2.1 4.9 1.5 9.5 8.9 6.1 10.2 24.6 10.3 7.0 10.9 9.8 10.2 6.5 5.2 2.7 17.4 6.2 10.9 27.1 3.3 3.9 7.9 1.9 11.2 5.2 2.5 8.5 4.5 14.4 2.1 8.4 10.0 12.5 7.9 10.9 10.9 7.1 8.6 2.9 6.3 10.1 10.5 4.8 10.6 3.8 8.8 10.5 7.5 3.7 4.1 7.5 4.4 5.0 6.1 6.2 7.6 4.6 4.4 9.0 3.2 6.2 22.6 9.7 16.2 6.5 3.8 5.4 6.5 16.4 2.5 5.1 0.0 1.8 0.3 3.4 0.4 3.0 0.8 1.4 4.9 2.1 1.0 1.5 1.6 0.0 2.1 0.8 2.3 0.3 1.5 13.5 20.5 13.4 26.4 13.7 13.1 14.1 10.3 12.6 12.9 6.0 7.7 5.9 5.6 12.8 10.4 1.9 5.1 4.0 3.4 7.0 7.9 3.2 1.7 5.6 33.3 8.7 14.2 0.0 9.0 7.2 8.9 13.5 1.1 9.3 13.1 12.7 9.1 4.9 4.1 27.1 11.2 8.4 13.5 2.8 12.4 11.3 8.3 8.2 13.4 6.1 12.2 6.5 7.8 13.0 5.9 12.2 2.7 6.9 6.1 6.8 TESK2 ENSG00000070759 "Testis-specific kinase 2" Q96S53 1 45343883-45491166 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Spermatocytes: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 13.1;RT4: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm NA NA Nucleoplasm "HPA027257: AB_10602477, HPA063869: AB_2685137" "unprognostic (2.95e-1)" "prognostic favorable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 5.5 3.3 6.1 5.9 17.4 12.6 9.6 7.8 12.6 7.7 8.4 25.7 4.0 11.9 4.7 5.7 9.1 4.1 3.9 5.8 9.6 5.1 3.5 9.7 5.5 6.0 19.2 4.7 14.4 4.6 6.7 4.1 8.3 13.2 22.1 10.1 7.6 11.2 5.7 10.1 17.1 14.8 4.4 18.7 6.3 5.6 11.7 14.8 4.2 5.1 3.2 7.2 8.2 9.7 7.5 2.0 15.9 5.9 1.1 3.7 2.6 1.6 0.0 0.8 0.0 3.2 1.7 13.1 0.6 4.3 1.9 3.2 3.6 1.5 5.3 0.6 1.6 4.9 2.0 3.4 2.7 1.5 3.7 4.3 3.6 1.8 2.7 1.7 1.2 9.9 1.8 2.9 2.1 3.0 2.9 1.5 7.1 0.6 10.9 1.3 0.6 3.0 2.4 3.4 1.5 1.5 4.4 0.1 1.4 1.7 12.8 0.3 1.4 3.4 6.4 12.2 8.1 10.0 1.5 0.0 0.2 2.0 1.6 1.1 7.2 4.2 1.0 1.0 0.0 0.8 9.4 3.8 10.6 2.4 2.8 1.7 7.5 2.2 1.6 2.0 5.7 3.7 2.1 15.9 1.1 5.9 1.1 1.5 2.6 6.1 17.4 7.8 12.6 9.6 5.1 19.2 4.7 13.2 14.8 0.0 3.2 2.4 6.5 6.9 2.3 1.1 5.1 1.4 3.4 0.0 13.7 6.5 0.0 1.0 18.1 2.9 12.4 0.0 2.3 2.5 2.2 12.9 6.9 5.5 5.9 0.0 4.1 1.3 4.6 5.2 2.6 4.5 3.3 2.8 5.3 1.1 1.0 7.4 1.8 0.6 2.8 6.5 4.7 26.8 5.7 7.4 12.4 4.4 4.9 7.3 TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "testis: 52.7" "Cell type enhanced" "Detected in many" 15 "Early spermatids: 13.5;Spermatocytes: 29.0;Spermatogonia: 15.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 9.1;Karpas-707: 11.9;MCF7: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" Vesicles "HPA030620: AB_10601598, HPA077020: AB_2732327" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-1)" "unprognostic (9.49e-2)" "unprognostic (2.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.61e-3)" "unprognostic (2.67e-2)" "unprognostic (8.10e-2)" "unprognostic (1.76e-9)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (5.00e-3)" "unprognostic (5.88e-2)" 0.1 0.1 0.2 0.1 0.3 1.5 0.1 0.9 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.1 0.4 0.2 0.0 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.5 0.2 0.0 52.7 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.8 0.2 0.1 0.0 0.2 2.6 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.2 0.0 0.2 0.0 0.4 0.0 0.2 9.1 1.4 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.1 11.9 0.0 4.8 0.4 0.1 0.6 0.1 0.1 0.5 0.4 1.8 0.0 0.1 1.4 0.2 0.0 0.1 0.6 0.4 0.4 0.1 0.0 0.1 0.3 0.0 0.0 2.1 0.5 1.1 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.8 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.9 0.2 0.3 0.2 0.2 0.1 0.4 0.1 0.0 0.0 0.0 1.2 0.8 0.4 1.4 5.1 0.0 2.3 1.8 0.0 0.9 0.0 0.0 13.5 0.2 0.0 0.0 0.0 0.7 0.6 0.6 1.1 0.4 3.1 0.0 0.0 1.8 1.2 3.6 0.3 2.4 3.3 0.0 0.0 0.5 0.1 0.0 0.4 0.0 1.1 0.0 0.9 29.0 15.8 0.1 0.9 0.0 0.0 0.3 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Early spermatids: 114.1;Late spermatids: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 11.1 6.9 10.3 11.5 14.6 20.0 15.4 12.6 11.3 14.4 20.0 11.0 5.5 7.4 18.8 8.0 13.2 10.9 14.9 9.7 7.8 7.5 16.0 9.8 19.2 18.9 15.8 4.3 13.3 8.8 6.5 13.5 50.9 14.1 12.3 9.2 10.4 10.2 12.2 8.4 6.6 11.0 28.6 17.9 13.9 25.5 11.4 12.4 10.8 7.7 8.1 11.5 13.0 10.2 1.6 2.0 13.1 2.4 4.0 8.3 1.9 3.4 5.2 31.4 9.7 7.3 5.4 4.7 11.7 12.9 11.0 12.3 5.2 2.5 7.6 3.6 9.1 8.7 8.1 10.6 9.1 14.8 19.9 3.3 11.4 5.7 4.6 12.1 7.0 27.9 11.2 9.8 17.1 8.1 6.9 1.9 2.9 15.8 3.2 15.0 5.3 1.0 8.0 6.7 3.2 3.1 2.8 68.5 3.2 2.7 0.8 8.5 9.9 9.1 40.7 12.2 13.5 7.5 9.6 3.6 8.2 7.1 35.0 7.1 3.3 3.3 5.2 17.2 12.1 7.0 13.1 2.4 9.1 8.3 1.6 7.2 1.6 3.6 6.1 2.0 1.3 3.5 6.7 4.9 4.0 1.9 1.4 2.2 1.9 10.3 14.6 12.6 11.3 7.8 7.5 15.8 4.3 14.1 12.4 6.0 9.1 9.3 6.5 20.9 7.2 6.3 5.1 1.4 10.3 57.6 0.0 17.0 0.0 14.1 114.1 14.5 3.3 23.3 27.1 5.9 46.2 13.4 29.9 11.5 43.1 0.0 9.2 8.0 20.9 74.1 8.9 36.3 33.7 19.0 6.6 2.9 25.9 3.5 12.7 12.2 1.6 32.3 22.2 8.0 10.5 14.2 16.2 11.5 7.2 8.4 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606502-30694142 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease mutation, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 14 "Endothelial cells: 188.8;Ito cells: 564.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;ASC TERT1: 82.2;HSkMC: 70.9;LHCN-M2: 67.2;TIME: 61.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 560000 "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 91.8 24.6 6.7 24.6 10.3 7.3 88.3 3.6 7.3 36.5 42.6 9.8 18.6 13.2 42.6 23.3 36.2 28.4 42.6 73.5 6.9 5.2 32.6 21.9 52.6 75.7 12.6 3.7 22.2 26.0 17.4 10.3 24.2 9.9 35.2 17.5 27.9 22.5 19.5 34.9 17.0 31.3 37.2 12.0 68.7 26.8 15.4 8.2 19.3 40.9 16.8 26.9 48.0 82.0 5.3 6.8 20.0 6.6 1.4 19.7 3.9 2.5 14.7 0.9 0.0 54.5 82.2 2.5 12.8 18.0 4.4 4.4 3.3 13.6 0.3 46.2 17.1 5.2 5.1 0.6 18.7 7.3 1.0 1.3 1.4 1.7 16.5 23.3 2.3 12.1 70.9 16.6 19.0 18.4 20.2 47.6 1.7 0.3 0.0 67.2 0.2 2.3 1.7 0.4 12.8 5.9 2.1 5.9 0.3 23.6 6.0 0.0 0.9 3.8 1.0 3.6 1.2 0.0 2.5 61.6 21.7 5.4 9.8 4.8 0.5 0.0 2.0 13.0 2.5 8.7 6.9 2.9 20.0 3.5 3.0 3.2 4.0 5.4 4.2 2.6 5.3 19.7 9.1 12.6 1.4 6.6 6.8 1.2 3.9 6.7 10.3 3.6 7.3 6.9 5.2 12.6 3.7 9.9 8.2 134.0 83.8 41.5 14.2 33.2 1.9 64.1 48.4 12.0 53.4 26.2 0.0 5.3 3.3 11.4 2.0 188.8 9.7 0.0 13.8 4.3 48.1 7.3 28.9 45.3 27.1 0.0 8.1 564.1 139.2 2.0 30.5 46.1 28.7 1.8 11.9 0.2 25.3 10.8 44.6 5.6 0.9 32.3 36.0 0.3 1.1 26.7 3.1 39.4 13.0 9.0 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300993-43323108 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Endothelial cells: 81.7;Ito cells: 106.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "basophil: 3.4;NK-cell: 5.4" "Group enriched" "Detected in many" 22 "granulocytes: 3.4;NK-cells: 5.4" "Group enriched" "Detected in some" 5 "EFO-21: 28.5;HUVEC TERT2: 63.1;TIME: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 75000000 "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 39.4 5.4 3.9 6.6 6.0 1.0 43.6 2.5 6.0 10.8 8.4 4.5 4.2 4.5 18.6 10.9 7.8 10.2 11.1 15.1 4.9 4.2 9.4 10.8 22.0 13.1 6.4 3.1 7.0 3.0 2.7 5.1 39.9 5.5 8.6 3.0 6.9 6.0 6.9 17.8 4.2 5.8 12.1 5.3 14.8 5.1 5.1 3.8 1.1 13.9 10.2 3.1 9.0 14.7 0.0 0.2 3.4 0.0 5.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 10.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 63.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.3 0.0 0.0 2.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 54.8 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.4 0.0 0.1 0.0 0.0 3.9 6.0 2.5 6.0 4.9 4.2 6.4 3.1 5.5 3.8 0.0 6.2 0.0 0.6 1.9 0.3 3.4 0.0 6.7 3.4 0.0 0.0 0.1 0.0 0.0 1.5 81.7 0.0 0.0 0.2 0.1 1.4 0.6 19.7 0.9 0.4 0.0 0.0 106.2 8.6 1.5 2.0 1.6 1.7 0.0 0.0 0.2 0.0 0.0 0.7 0.8 0.7 0.0 0.9 0.7 0.1 1.3 0.2 6.9 0.0 0.6 TLK1 "KIAA0137, PKU-BETA" ENSG00000198586 "Tousled like kinase 1" Q9UKI8 2 170990823-171231314 "Enzymes, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016043 Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA016043: AB_1858027" "unprognostic (2.13e-2)" "unprognostic (3.87e-1)" "unprognostic (7.36e-2)" "unprognostic (6.00e-3)" "unprognostic (2.00e-1)" "unprognostic (6.78e-2)" "unprognostic (2.47e-2)" "unprognostic (7.60e-2)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (2.57e-1)" "unprognostic (1.11e-1)" "unprognostic (6.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.55e-1)" "unprognostic (2.63e-1)" "unprognostic (1.53e-1)" 13.8 20.1 22.0 32.9 21.0 14.4 26.2 18.3 23.2 19.6 20.2 8.4 22.3 13.7 16.1 16.1 14.1 14.4 16.2 12.7 20.6 19.3 19.5 21.4 22.1 33.7 21.7 20.8 21.5 19.8 37.8 21.0 36.0 18.3 18.0 18.2 10.8 16.4 30.3 18.6 15.4 18.9 20.5 18.7 26.0 19.9 24.2 12.2 28.0 25.7 11.1 21.7 21.9 19.1 10.5 5.3 11.3 5.5 9.5 12.3 6.6 8.6 8.5 12.3 9.6 8.8 8.8 13.6 12.1 17.6 12.2 10.2 11.7 14.2 18.0 9.9 18.1 13.2 7.4 15.6 13.5 13.4 21.4 7.8 20.8 10.6 15.1 9.5 26.3 10.5 9.6 13.8 24.2 16.0 13.0 13.3 11.6 21.3 15.4 7.3 10.8 22.1 8.4 11.3 8.4 4.8 16.7 14.9 18.6 10.0 16.7 14.0 10.9 13.1 9.3 8.9 8.7 7.6 9.2 18.1 10.9 13.4 7.1 9.4 12.9 21.7 32.7 13.5 10.9 10.9 11.3 3.9 6.5 6.6 3.0 9.1 10.5 10.7 7.2 3.5 10.5 12.3 8.1 5.0 9.5 5.5 5.3 10.0 6.6 22.0 21.0 18.3 23.2 20.6 19.3 21.7 20.8 18.3 12.2 47.6 23.8 55.6 30.2 36.7 31.7 26.5 28.1 33.5 29.6 48.8 56.9 70.8 74.6 24.8 57.8 27.4 38.0 23.3 28.2 44.9 25.5 42.8 26.5 30.0 23.9 42.9 23.0 12.3 25.7 21.5 40.0 26.9 35.4 15.4 31.6 25.5 28.4 34.8 42.1 38.3 72.6 0.0 28.8 29.9 22.6 34.3 146.2 48.0 28.0 31.4 TLK2 "MGC44450, PKU-ALPHA" ENSG00000146872 "Tousled like kinase 2" Q86UE8 17 62458658-62615481 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.9" "Cell type enhanced" "Detected in all" 5 "Late spermatids: 128.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "unprognostic (2.50e-2)" "unprognostic (2.12e-1)" "unprognostic (7.06e-2)" "unprognostic (1.48e-2)" "unprognostic (9.53e-3)" "unprognostic (6.57e-2)" "prognostic unfavorable (9.40e-4)" "unprognostic (4.53e-2)" "unprognostic (5.28e-2)" "unprognostic (2.32e-1)" "unprognostic (2.82e-2)" "unprognostic (4.78e-2)" "unprognostic (5.32e-2)" "unprognostic (9.79e-2)" "unprognostic (4.32e-2)" "unprognostic (4.88e-1)" "unprognostic (7.30e-2)" 7.4 6.4 8.3 7.3 7.2 12.0 12.5 7.8 14.0 5.8 7.8 4.0 3.1 7.4 9.0 3.1 9.0 6.2 9.9 17.8 7.7 7.4 5.7 5.0 6.9 8.7 7.7 7.3 8.5 8.9 5.6 6.9 9.0 10.4 6.6 5.3 7.5 8.6 8.7 11.7 8.7 10.1 6.5 8.6 8.9 6.7 47.9 5.7 4.1 11.7 3.1 10.0 8.5 7.2 4.6 3.6 8.6 2.8 6.6 4.9 1.5 15.8 14.6 25.2 26.6 8.2 10.7 14.7 17.5 13.6 20.7 19.0 15.1 14.2 31.0 9.0 11.4 18.3 10.8 17.7 7.5 19.8 16.4 14.1 21.1 13.7 15.2 14.7 22.2 13.4 9.2 10.2 13.9 16.9 12.7 10.2 17.7 20.8 14.1 11.1 34.5 31.6 7.9 16.0 9.3 12.2 21.7 33.2 9.8 9.8 15.9 27.2 36.7 14.9 10.2 22.4 22.1 17.3 20.0 13.8 29.1 27.7 13.1 19.7 16.4 20.4 28.4 12.0 11.4 15.2 3.7 2.8 8.6 2.5 2.2 2.6 4.5 4.4 3.1 2.5 4.6 3.5 4.6 5.5 6.6 2.4 3.6 4.9 1.5 8.3 7.2 7.8 14.0 7.7 7.4 7.7 7.3 10.4 5.7 29.8 22.4 16.6 13.3 20.1 58.1 26.4 12.7 38.8 12.5 14.0 78.5 9.5 10.0 8.7 90.3 13.1 14.6 23.3 8.6 9.8 15.0 18.6 19.7 8.3 10.8 27.0 17.2 11.1 14.2 128.6 19.5 18.0 16.9 10.0 14.2 23.8 12.6 23.0 16.6 6.3 82.2 6.5 16.0 73.9 28.9 19.2 12.7 14.1 15.1 20.0 TNIK KIAA0551 ENSG00000154310 "TRAF2 and NCK interacting kinase" Q9UKE5 3 171061339-171460408 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.9" "Cell type enhanced" "Detected in many" 7 "granulocytes: 79.9;Muller glia cells: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 23 "basophil: 4.4;eosinophil: 10.5;gdT-cell: 4.2;MAIT T-cell: 5.2;memory CD4 T-cell: 5.0;memory CD8 T-cell: 3.7;naive CD4 T-cell: 6.7;naive CD8 T-cell: 3.8;NK-cell: 2.7;T-reg: 5.3" "Group enriched" "Detected in many" 29 "granulocytes: 10.5;NK-cells: 2.7;T-cells: 6.7" "Cell line enhanced" "Detected in many" "AF22: 19.9;HEL: 27.0;HMC-1: 30.8;WM-115: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012128, HPA012297" Approved Supported Nucleoplasm,Cytosol NA NA 9100 Nucleoplasm Cytosol "HPA012128: AB_1858226, HPA012297: AB_1858225" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (1.32e-1)" "unprognostic (5.90e-2)" "unprognostic (5.25e-2)" "unprognostic (9.23e-2)" "unprognostic (4.91e-2)" "unprognostic (2.41e-3)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (5.91e-2)" "unprognostic (1.96e-2)" "unprognostic (3.34e-3)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (2.13e-2)" "unprognostic (3.97e-2)" 2.2 5.4 29.0 7.4 30.9 4.9 3.6 21.1 26.1 1.9 10.9 12.2 4.1 25.8 4.3 2.1 5.6 4.3 7.1 11.2 30.9 14.8 5.6 4.6 11.3 7.9 11.4 18.3 2.6 5.2 0.7 9.0 3.1 13.6 5.6 9.5 3.5 2.9 7.3 23.2 1.6 25.6 6.0 14.5 5.8 9.2 10.7 21.1 3.7 7.1 2.2 6.9 6.4 2.6 0.2 0.0 10.5 0.1 2.7 6.7 1.1 0.3 0.5 19.9 2.1 0.3 0.0 4.7 4.1 1.2 3.3 2.2 17.8 7.4 0.0 1.5 3.8 3.0 6.1 2.8 1.1 3.6 0.1 4.4 27.0 1.5 0.0 9.5 5.3 30.8 2.9 3.0 1.9 0.4 7.7 19.8 4.5 9.7 0.0 0.5 0.4 1.7 6.8 8.2 14.2 7.7 0.0 5.1 7.1 6.4 0.0 0.9 1.0 2.5 0.2 4.4 2.2 9.0 1.3 0.2 0.0 3.5 9.0 3.0 0.0 0.0 0.0 0.9 6.0 23.0 4.4 0.1 10.5 4.2 0.0 5.2 0.0 5.0 3.7 0.0 0.2 6.7 3.8 0.1 2.7 0.1 0.0 5.3 1.1 29.0 30.9 21.1 22.2 30.9 14.8 11.4 18.3 13.6 21.1 6.0 37.9 0.5 1.4 2.3 9.3 25.7 25.5 2.7 12.5 8.7 13.7 4.7 5.0 9.2 29.5 1.6 26.2 0.0 6.8 1.8 4.4 0.6 79.9 6.8 2.5 0.0 12.7 1.3 5.6 33.0 2.3 3.3 1.7 0.0 9.4 79.4 4.8 16.5 6.0 14.9 27.7 0.0 7.6 2.8 1.0 1.4 2.1 31.2 15.3 2.4 TNK1 ENSG00000174292 "Tyrosine kinase non receptor 1" Q13470 17 7380534-7389774 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" 5 "Enterocytes: 10.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 6.4;cerebellum: 11.4;cerebral cortex: 4.0;pons and medulla: 4.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 6 "B-cells: 1.6;T-cells: 3.8" "Cell line enhanced" "Detected in many" "HaCaT: 10.5;HBEC3-KT: 7.0;hTCEpi: 7.9;T-47d: 8.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA012065, HPA056452" Uncertain Approved "Cell Junctions" NA NA "Cell Junctions" "HPA012065: AB_1858165, HPA056452: " "unprognostic (4.90e-2)" "unprognostic (1.93e-1)" "unprognostic (2.95e-1)" "prognostic favorable (4.28e-4)" "unprognostic (2.84e-1)" "unprognostic (1.60e-1)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.20e-1)" "unprognostic (2.52e-2)" "unprognostic (2.43e-1)" "unprognostic (3.10e-1)" "prognostic favorable (6.40e-4)" "unprognostic (1.77e-3)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.52e-4)" 3.4 0.6 1.1 2.2 6.4 0.4 7.9 11.4 4.0 5.4 11.7 0.4 7.7 7.1 5.1 5.3 7.2 3.5 6.3 2.0 1.0 0.4 4.6 6.9 3.2 2.7 1.5 0.8 4.4 6.8 5.4 2.7 2.5 4.3 8.9 4.5 7.7 10.5 4.8 1.8 8.3 11.3 5.1 0.7 2.4 9.6 2.2 0.6 0.6 11.6 5.7 5.2 4.5 4.4 1.6 0.1 0.4 0.0 0.0 3.8 0.6 6.4 1.0 0.2 0.4 0.0 0.0 4.4 0.2 0.0 0.4 0.4 3.3 3.0 0.0 2.6 0.3 0.1 10.5 0.0 7.0 0.1 0.7 1.5 0.0 3.7 1.9 0.4 0.0 0.3 0.1 7.9 0.0 1.2 0.2 0.0 2.8 0.8 0.0 0.0 4.9 0.6 0.0 0.9 5.6 0.9 0.2 0.2 0.7 4.9 3.0 0.2 0.5 3.6 5.3 1.0 0.3 8.7 0.1 1.7 0.2 0.8 0.2 0.0 0.5 1.0 0.1 0.1 0.4 0.5 0.0 0.0 0.0 1.0 0.0 1.9 1.6 1.8 1.2 0.1 1.5 3.3 3.8 0.4 0.0 0.0 0.0 0.8 0.6 1.1 6.4 11.4 4.0 1.0 0.4 1.5 0.8 4.3 0.6 6.0 4.3 0.5 2.1 2.3 1.2 0.8 2.5 0.0 2.3 1.8 0.0 0.2 0.0 4.4 1.1 0.7 10.4 0.0 5.9 0.4 1.0 4.0 0.0 2.5 0.1 0.0 2.9 1.3 0.0 0.6 1.1 0.1 0.0 0.0 6.3 0.2 6.4 6.5 0.4 1.4 2.4 0.0 0.9 0.6 0.9 2.0 0.6 1.0 6.4 1.8 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 10 "Cone photoreceptor cells: 47.1;Horizontal cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041954 Approved Approved Cytosol NA NA Cytosol "HPA041954: AB_10794164" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavorable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.00e-4)" 9.2 7.6 36.3 16.2 27.6 38.9 8.5 20.7 43.7 6.0 6.3 17.6 3.8 6.6 8.0 6.6 13.0 10.7 6.5 10.6 28.4 21.8 4.1 7.2 9.3 18.1 21.6 31.8 8.6 7.8 5.1 19.3 8.4 20.0 10.8 3.9 5.3 16.8 8.2 30.5 37.1 6.9 7.6 10.3 17.0 12.1 7.7 21.8 3.4 4.6 9.8 12.8 7.7 12.3 6.1 3.1 6.3 3.2 0.9 1.9 1.2 31.9 3.1 5.2 5.5 7.2 4.6 31.1 6.2 5.9 3.7 3.4 4.9 24.7 9.3 21.6 8.4 6.3 11.4 4.5 7.6 1.1 21.9 5.7 8.4 10.4 3.5 3.2 4.3 4.2 3.4 12.2 5.1 6.1 10.6 4.7 3.5 3.4 12.9 3.4 23.5 1.8 15.7 4.9 8.5 11.5 5.4 6.2 9.4 3.3 15.5 6.3 6.4 4.0 16.2 7.9 5.2 26.5 5.4 7.6 8.6 5.0 4.4 17.1 28.2 3.0 5.8 7.7 14.0 6.3 2.0 2.4 0.9 1.9 3.2 1.1 2.7 1.8 1.0 1.1 6.1 1.4 1.3 6.3 0.9 2.8 3.1 0.2 1.2 36.3 27.6 20.7 33.3 28.4 21.8 21.6 31.8 20.0 21.8 6.0 4.8 11.8 6.8 6.2 26.5 12.8 5.1 5.3 11.4 0.0 47.1 10.6 1.7 3.5 0.8 7.5 6.9 0.0 4.5 2.6 5.3 7.2 1.1 13.5 7.2 93.8 5.8 9.8 20.5 0.8 6.1 11.4 5.0 9.0 1.4 6.6 19.1 3.5 6.0 1.4 20.9 0.0 5.5 3.9 10.0 9.3 3.5 8.9 3.3 16.3 TNNI3K CARK ENSG00000116783 "TNNI3 interacting kinase" Q59H18 1 74235401-74544428 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "heart muscle: 44.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 23.4;Early spermatids: 20.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "intermediate monocyte: 2.3;plasmacytoid DC: 1.9" "Group enriched" "Detected in many" 5 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 1.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.8;HSkMC: 2.6;OE19: 2.8;RPTEC TERT1: 2.6" NA NA "unprognostic (1.04e-2)" "unprognostic (1.34e-2)" "unprognostic (3.83e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-1)" "unprognostic (3.40e-2)" "unprognostic (3.05e-1)" "unprognostic (2.48e-3)" "unprognostic (2.00e-1)" "unprognostic (9.66e-2)" "unprognostic (5.04e-2)" "unprognostic (1.80e-1)" "unprognostic (3.59e-3)" "unprognostic (4.88e-3)" "unprognostic (1.20e-1)" "unprognostic (8.80e-2)" "unprognostic (8.77e-2)" 0.7 0.6 1.1 0.5 1.5 0.0 1.0 6.0 1.7 0.5 0.5 0.5 0.5 0.2 0.5 1.7 0.5 0.7 0.5 44.6 1.1 1.3 2.2 0.5 0.5 0.5 0.6 0.5 0.7 0.5 0.3 0.6 0.5 0.9 0.5 0.3 0.5 0.5 1.2 0.5 0.9 0.5 0.6 0.5 0.5 0.1 1.8 0.5 0.5 0.6 0.5 0.5 0.5 0.5 0.3 1.9 0.0 2.3 0.0 1.0 0.1 0.0 0.6 0.7 0.0 0.5 1.5 0.0 0.0 1.3 0.3 1.0 0.0 3.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.5 2.6 1.5 0.2 0.0 0.0 0.5 0.3 0.0 0.8 1.1 0.0 0.2 0.2 1.1 2.8 0.0 0.2 0.0 0.0 2.6 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.8 1.3 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.5 0.3 0.0 0.2 0.0 0.1 2.3 0.0 0.1 0.3 1.0 0.1 0.3 0.2 0.4 0.0 0.0 0.2 1.9 0.0 0.1 1.1 1.5 6.0 1.7 1.1 1.3 0.6 0.5 0.9 0.5 0.0 0.0 0.0 0.1 0.8 1.2 23.4 0.0 0.0 0.0 1.8 0.0 0.0 1.7 0.1 20.4 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 1.6 0.0 0.0 0.0 5.4 0.9 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.7 3.3 0.2 0.0 1.7 0.4 1.1 0.3 0.1 0.0 0.0 0.1 TP53RK "BUD32, C20orf64, dJ101A2.2, Nori-2p, prpk" ENSG00000172315 "TP53 regulating kinase" Q96S44 20 46684365-46689779 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 70.6" "Low region specificity" "Detected in all" "CAB004688, HPA015837" Approved NA NA "CAB004688: AB_426116, HPA015837: AB_1855776" "unprognostic (9.45e-2)" "unprognostic (3.73e-1)" "unprognostic (9.76e-2)" "prognostic unfavorable (6.70e-5)" "unprognostic (4.41e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (9.16e-3)" "unprognostic (6.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-1)" "unprognostic (5.72e-2)" "unprognostic (1.25e-2)" "unprognostic (3.37e-2)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (1.74e-2)" 11.2 14.5 12.7 12.6 15.3 9.6 16.8 8.1 20.3 14.1 11.7 13.7 5.3 8.8 14.8 8.9 16.9 12.2 12.6 9.9 12.1 11.3 12.7 13.6 10.6 18.2 13.1 12.8 15.3 10.1 11.8 15.7 14.9 12.1 15.5 11.4 12.6 13.8 12.2 12.4 16.8 11.2 12.7 10.6 13.2 13.3 26.4 11.8 21.9 16.6 13.1 21.1 14.3 12.7 14.7 19.1 21.7 12.4 16.2 18.5 12.2 4.0 2.8 5.9 5.2 6.3 5.2 5.4 5.7 5.3 7.5 5.5 7.9 2.6 9.7 8.6 4.7 6.8 6.3 7.5 6.5 6.6 2.4 3.8 9.8 2.8 7.0 8.3 6.3 70.6 6.9 8.0 5.2 5.2 3.5 4.9 4.1 6.6 4.3 6.4 6.0 9.5 10.5 4.8 5.8 9.4 5.6 5.3 5.7 5.0 4.4 7.1 3.7 6.9 13.9 27.6 3.2 5.0 7.0 5.0 8.8 5.1 5.7 6.3 4.7 5.8 7.7 5.1 4.8 4.1 21.7 12.4 20.6 13.7 11.5 15.8 14.7 14.8 15.6 12.6 14.2 16.4 14.0 2.0 16.2 10.2 19.1 18.5 12.2 12.7 15.3 8.1 20.3 12.1 11.3 13.1 12.8 12.1 11.8 8.9 12.5 16.4 45.5 45.1 8.7 5.7 12.7 5.3 10.3 8.7 11.8 36.5 23.2 24.6 176.8 13.1 10.9 0.0 20.7 62.1 26.2 45.0 23.0 12.1 23.0 14.3 12.6 12.3 13.1 26.3 20.4 12.4 35.4 20.8 14.8 8.0 29.4 3.5 15.2 25.4 9.8 6.5 23.7 35.2 15.3 54.1 74.1 17.5 12.3 49.2 TRIB1 "C8FW, GIG2, TRB1" ENSG00000173334 "Tribbles pseudokinase 1" Q96RU8 8 125430321-125438405 "Enzymes, Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.2;thyroid gland: 90.7" "Cell type enhanced" "Detected in many" 6 "Alveolar cells type 2: 192.3;Basal glandular cells: 267.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 10.8;neutrophil: 5.8;non-classical monocyte: 3.7;T-reg: 3.1" "Group enriched" "Detected in many" 11 "granulocytes: 10.8;monocytes: 3.7;T-cells: 3.1" "Cell line enhanced" "Detected in many" "HEL: 55.1;U-266/70: 33.8;U-266/84: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063982 Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane, Cytosol" "HPA063982: AB_2685165" "unprognostic (1.90e-3)" "unprognostic (1.45e-1)" "unprognostic (8.80e-3)" "unprognostic (1.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.57e-2)" "unprognostic (4.12e-2)" "unprognostic (1.62e-2)" "unprognostic (6.81e-3)" "unprognostic (9.36e-2)" "unprognostic (2.97e-3)" "unprognostic (1.94e-1)" "unprognostic (1.04e-2)" "unprognostic (5.55e-2)" "unprognostic (2.08e-2)" 26.7 6.5 5.9 17.6 6.5 84.2 13.3 4.3 6.1 10.4 12.4 4.4 6.6 4.9 6.2 6.7 10.9 10.9 21.0 11.1 4.3 4.0 16.6 63.5 28.9 14.6 4.2 3.9 6.4 23.6 20.9 7.2 15.5 4.5 12.1 13.3 15.0 14.5 9.1 22.3 10.4 16.9 11.3 3.1 15.9 18.5 5.6 3.1 9.2 90.7 17.6 12.1 12.4 9.0 0.2 0.5 10.8 3.7 0.0 3.1 0.1 4.1 4.7 0.6 1.3 1.3 2.7 7.5 2.7 3.8 2.0 0.6 6.3 5.5 7.5 2.5 1.9 12.1 3.1 2.0 2.6 1.7 3.3 9.9 55.1 2.1 12.3 3.5 27.5 5.0 2.6 4.0 8.2 18.8 9.8 5.8 0.1 4.8 24.0 0.2 4.4 2.5 4.3 4.6 9.9 9.2 5.2 0.9 8.2 16.2 15.8 4.0 1.5 6.6 7.2 26.2 4.3 1.9 1.3 3.0 2.2 2.8 2.1 3.3 33.8 33.7 10.5 3.9 0.2 5.1 0.0 0.9 10.8 0.0 1.2 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 5.8 0.0 3.7 0.3 3.1 0.1 5.9 6.5 4.3 6.1 4.3 4.0 4.2 3.9 4.5 3.1 125.0 192.3 11.2 267.7 89.0 20.4 14.4 17.8 33.5 64.8 15.7 0.0 9.2 10.0 31.3 0.4 32.9 172.0 0.0 21.2 17.2 32.4 153.9 29.9 128.8 29.9 20.6 107.4 8.6 53.9 1.4 0.3 47.3 54.0 40.5 87.2 21.4 42.4 51.5 0.4 21.6 3.4 0.0 14.4 0.0 1.3 56.1 25.6 4.5 56.6 79.9 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Exocrine glandular cells: 89.7;Muller glia cells: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-reg: 24.8" "Group enriched" "Detected in many" 9 "B-cells: 7.1;NK-cells: 9.5;T-cells: 24.8" "Cell line enhanced" "Detected in many" "AN3-CA: 41.0;HEL: 40.3;K-562: 54.8;SK-MEL-30: 40.0;WM-115: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Nucleoplasm, Cytosol" "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 19.6 30.9 13.2 17.7 13.3 7.0 23.2 23.2 23.0 10.8 12.3 10.5 6.7 8.7 23.0 22.6 8.1 11.6 14.5 18.2 15.0 10.8 24.8 10.6 18.9 33.0 13.4 16.2 52.3 14.4 6.6 11.3 23.0 15.5 16.3 6.9 35.7 9.9 13.6 6.9 8.2 11.9 17.6 10.4 38.9 19.5 13.9 10.1 37.3 12.1 6.2 33.4 21.9 23.2 7.1 0.6 1.5 0.1 9.5 24.8 4.5 0.0 0.0 31.3 41.0 11.3 10.4 0.0 1.7 1.6 1.1 1.8 0.2 3.4 3.5 1.2 3.7 0.2 0.5 2.3 3.5 0.9 3.9 6.4 40.3 0.1 0.6 14.0 2.2 15.4 9.6 3.6 4.5 1.2 11.1 4.9 5.3 54.8 0.0 1.7 0.3 5.1 9.6 14.8 1.5 4.0 0.0 10.4 1.4 7.1 5.1 26.9 12.8 0.2 1.6 40.0 9.8 0.0 0.2 3.0 14.9 7.5 0.1 3.8 0.0 0.0 5.0 8.0 7.9 54.9 0.8 0.1 1.5 7.3 0.0 8.8 5.3 14.4 7.7 0.6 7.1 8.5 5.2 0.3 9.5 0.1 0.0 24.8 4.5 13.2 13.3 23.2 23.0 15.0 10.8 13.4 16.2 15.5 10.1 3.0 8.8 8.0 10.2 5.5 46.7 13.3 20.4 6.7 11.4 15.7 29.5 1.9 6.6 13.3 3.9 36.4 0.0 0.0 89.7 0.1 7.1 10.3 33.5 5.4 4.4 19.1 0.0 63.3 5.3 10.7 71.7 2.5 28.7 1.8 0.0 115.1 49.1 0.0 70.0 0.7 66.1 51.8 22.5 0.9 2.7 4.6 0.7 20.8 0.0 11.1 TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 39.0;salivary gland: 47.5" "Cell type enhanced" "Detected in many" 8 "Ductal cells: 49.9;Hepatocytes: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 88.9;hTCEpi: 55.1;hTERT-HME1: 64.0;SK-MEL-30: 80.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm NA NA Nucleoplasm "HPA015272: AB_1858269, HPA055442: AB_2682818" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.70e-4)" "prognostic unfavorable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" 4.8 8.7 1.6 2.8 1.5 9.7 6.0 3.8 4.2 2.5 1.8 1.2 3.6 1.0 2.1 3.1 9.8 1.1 2.7 3.0 1.4 2.0 3.3 39.0 8.2 7.3 1.0 2.4 4.4 13.8 2.0 10.5 6.2 1.6 3.9 1.6 3.7 47.5 5.3 1.5 6.5 2.5 1.3 0.7 7.9 4.4 2.7 0.6 6.7 27.2 4.1 7.0 2.7 5.3 15.5 4.7 3.3 4.4 6.6 11.4 5.1 11.1 5.7 0.7 1.6 1.9 2.5 4.8 3.3 8.9 3.2 6.6 11.7 5.6 4.8 3.3 3.0 14.3 9.0 3.1 14.9 2.9 1.8 2.2 3.7 1.2 19.1 88.9 9.4 1.8 10.3 55.1 6.0 64.0 2.2 6.1 12.2 12.9 21.7 0.3 10.4 0.5 11.4 1.7 16.5 18.5 2.1 0.9 10.4 3.7 4.5 2.1 3.3 0.7 27.1 80.8 1.0 7.8 25.0 3.5 1.7 3.0 0.0 5.1 7.6 9.8 8.6 1.5 8.3 6.1 2.5 4.4 1.0 10.0 3.4 7.1 15.5 9.3 11.4 4.7 10.2 10.7 7.6 3.3 6.6 1.7 2.1 6.4 5.1 1.6 1.5 3.8 4.2 1.4 2.0 1.0 2.4 1.6 0.6 3.0 1.0 7.6 7.2 6.1 3.8 1.2 10.2 2.7 1.2 1.8 3.9 13.1 0.0 49.9 0.0 5.8 0.0 23.3 19.2 4.3 1.5 10.5 4.7 25.3 5.6 0.0 1.2 8.0 2.1 0.0 1.7 4.0 6.8 1.8 6.5 0.5 23.3 2.3 1.4 0.0 6.7 6.5 4.1 1.9 2.2 4.6 5.9 5.0 0.6 4.8 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143702-14532128 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease mutation, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 5 "Leydig cells: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 63.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol No No Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: AB_2685315" "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 29.7 13.7 27.6 15.8 18.9 5.8 30.3 32.6 29.7 13.7 18.5 11.3 9.2 8.3 23.1 19.3 10.4 12.2 25.2 15.1 18.9 15.0 11.7 12.6 15.8 10.9 11.0 17.7 28.9 11.5 17.2 19.6 13.7 12.3 16.3 16.5 23.3 10.5 14.0 19.8 16.0 15.6 22.7 11.6 24.2 13.7 11.3 11.5 7.4 10.0 11.9 12.3 15.6 16.9 3.8 2.7 0.3 1.9 4.3 0.6 0.4 12.3 4.4 10.7 5.1 23.0 30.2 12.3 11.5 13.7 9.2 10.6 2.8 4.9 2.8 8.6 15.5 22.5 3.8 1.8 5.4 19.1 7.9 2.5 1.5 12.0 3.5 11.9 3.8 4.3 14.1 5.7 32.5 10.4 8.7 8.1 1.9 0.3 1.9 22.3 2.3 0.0 2.6 2.7 1.3 4.0 2.8 6.5 9.5 9.0 5.6 4.9 19.7 9.7 2.5 5.1 14.1 1.5 0.6 18.8 17.8 11.3 12.9 13.5 0.0 0.6 3.6 63.2 2.5 4.2 0.3 1.5 0.0 0.1 1.9 0.3 2.0 0.0 0.0 1.4 3.8 0.0 0.0 0.0 4.3 1.4 2.7 0.6 0.4 27.6 18.9 32.6 29.7 18.9 15.0 11.0 17.7 12.3 11.5 17.9 23.4 9.0 13.2 14.5 29.9 15.7 10.2 16.0 22.7 10.4 13.7 7.6 0.0 18.3 1.9 24.8 13.6 0.0 12.1 17.8 12.4 32.5 17.3 15.3 13.2 27.0 17.3 11.1 12.3 2.4 72.8 16.8 5.0 6.4 21.7 7.1 29.1 16.1 40.3 2.9 3.0 6.5 11.5 2.8 6.4 12.0 6.9 4.6 17.1 20.1 TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 16.1;intestine: 19.5" "Group enriched" "Detected in many" 4 "Enterocytes: 28.8;Paneth cells: 10.5" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 16.1;neutrophil: 6.6" "Lineage enriched" "Detected in single" 30 "granulocytes: 16.1" "Cell line enhanced" "Detected in some" "BEWO: 7.7;HeLa: 4.5;Karpas-707: 2.6;RT4: 7.4;U-266/70: 2.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (7.80e-2)" "unprognostic (9.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (5.72e-4)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (8.10e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-2)" 2.9 0.0 1.3 0.5 1.2 2.5 1.1 1.3 1.2 0.8 13.3 0.2 1.0 7.2 0.4 0.2 0.6 0.4 1.0 0.5 1.9 1.2 3.1 0.2 1.5 0.2 2.6 0.0 0.4 0.2 3.8 4.9 0.2 1.6 1.7 17.5 0.4 1.1 0.0 1.6 0.8 19.5 0.7 5.0 3.9 0.2 1.7 0.5 1.6 0.3 1.1 2.1 0.5 0.6 0.3 0.3 16.1 0.1 0.5 0.1 0.0 0.1 1.7 0.2 0.2 0.0 0.0 7.7 0.1 0.0 0.0 0.1 2.1 0.2 0.6 0.0 0.1 0.3 0.3 0.5 0.5 0.0 0.1 0.2 0.2 4.5 0.3 0.1 0.1 0.2 0.3 0.2 0.0 0.0 0.1 0.2 0.3 0.0 2.6 0.1 0.9 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.3 0.0 7.4 0.3 0.0 0.0 0.1 0.1 0.4 0.3 0.0 0.0 0.2 1.1 0.2 0.0 2.8 0.0 0.2 0.1 0.1 0.3 16.1 0.1 1.9 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 6.6 0.5 0.1 0.3 0.0 0.0 1.3 1.2 1.3 1.2 1.9 1.2 2.6 0.0 1.6 0.5 0.0 1.7 0.0 1.7 0.1 0.2 0.6 0.0 1.4 2.3 3.5 0.0 0.2 0.0 0.0 2.5 0.7 28.8 0.0 0.0 0.1 0.3 1.1 0.0 0.0 0.0 0.0 3.5 4.9 0.3 0.4 0.0 0.2 0.0 0.0 3.3 0.1 0.0 10.5 0.4 0.0 2.3 0.0 0.3 1.5 2.3 0.9 0.1 0.0 2.6 0.9 TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686815 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 91.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: AB_2681749" "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" 13.3 10.8 6.6 14.7 9.0 12.8 12.1 19.5 9.3 11.8 11.7 8.1 9.7 9.9 16.5 10.7 9.4 11.0 8.2 19.1 5.5 4.9 16.0 20.0 10.8 10.6 12.4 5.2 16.6 11.6 91.8 14.6 14.3 10.2 9.7 10.3 28.6 11.5 13.5 10.8 11.7 12.8 12.8 9.8 11.1 10.3 6.9 10.0 14.5 12.6 6.9 12.6 12.9 12.3 7.0 4.7 4.4 3.4 5.7 7.6 2.0 8.5 8.5 7.1 7.9 20.6 15.5 8.7 10.8 15.0 6.9 9.1 11.7 4.7 18.6 5.3 12.4 17.8 14.4 9.5 7.9 9.9 10.3 5.7 14.8 13.1 6.1 18.8 15.3 11.5 14.4 9.4 7.8 14.7 10.1 5.5 11.8 16.7 14.3 12.5 13.4 9.8 7.5 5.4 11.8 5.3 10.8 9.9 9.1 9.6 20.2 5.9 7.5 7.4 11.9 14.5 13.1 7.4 16.7 8.4 11.0 5.2 50.9 12.4 9.7 21.5 17.9 11.9 31.3 10.2 3.8 3.4 3.9 6.6 3.2 7.6 5.6 4.8 4.4 3.7 7.0 4.4 5.2 4.4 5.7 3.2 4.7 4.8 2.0 6.6 9.0 19.5 9.3 5.5 4.9 12.4 5.2 10.2 10.0 17.9 25.3 18.2 14.9 28.0 22.9 21.4 28.1 24.1 7.9 12.2 11.8 18.5 3.3 9.7 25.2 18.5 16.9 23.3 11.1 8.0 17.0 21.2 16.3 35.0 12.7 20.6 17.7 15.4 18.6 17.9 24.5 17.0 18.6 14.4 17.3 9.1 12.8 12.9 19.1 9.6 21.5 12.9 13.7 13.6 19.4 21.1 13.6 17.5 16.3 9.0 TSSK1B "FKSG81, SPOGA4, STK22D, TSSK1" ENSG00000212122 "Testis specific serine kinase 1B" Q9BXA7 5 113432554-113435031 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "testis: 59.9" "Group enriched" "Detected in some" 101 "Early spermatids: 408.3;Late spermatids: 766.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.3;EFO-21: 2.1;RT4: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA027827 Enhanced NA NA "HPA027827: AB_10603138" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.6 0.1 0.2 0.0 1.0 0.0 0.0 0.0 0.2 0.0 1.3 0.2 2.1 0.0 0.4 0.4 0.2 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.6 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.6 0.1 0.0 0.1 0.1 0.3 0.0 0.4 0.0 0.5 0.2 0.2 0.3 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 408.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 766.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 5.8 3.2 0.0 0.0 0.0 0.0 0.0 TSSK2 "FLJ38613, SPOGA2, STK22B" ENSG00000206203 "Testis specific serine kinase 2" Q96PF2 22 19130808-19132623 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "testis: 95.7" "Group enriched" "Detected in some" 70 "Early spermatids: 1437.9;Late spermatids: 2322.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "NK-cell: 1.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 1.6;HL-60: 1.8;SCLC-21H: 3.5;THP-1: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 95.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.0 1.6 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.8 0.0 0.6 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.7 3.3 0.8 1.4 0.5 0.0 0.2 0.1 0.9 0.3 0.0 0.3 1.2 0.0 0.0 1.0 0.4 0.0 0.0 0.5 0.1 0.8 0.3 0.7 0.2 0.5 0.2 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1437.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2322.2 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 6.5 0.0 26.9 11.5 0.0 0.0 0.0 0.0 0.0 TSSK3 "SPOGA3, STK22C" ENSG00000162526 "Testis specific serine kinase 3" Q96PN8 1 32351521-32364312 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 68.1" "Group enriched" "Detected in some" 52 "Early spermatids: 242.3;Late spermatids: 839.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA037516 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA037516: AB_2675517" "unprognostic (5.71e-2)" "unprognostic (1.42e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-1)" "unprognostic (7.69e-2)" "unprognostic (2.02e-4)" "unprognostic (2.06e-1)" "unprognostic (1.98e-3)" "unprognostic (2.05e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (9.20e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.68e-3)" 1.1 2.0 0.8 1.7 0.8 8.2 1.1 3.9 0.8 1.3 0.9 0.8 1.4 2.5 1.8 2.9 0.8 1.3 1.0 0.9 0.8 0.0 0.9 1.3 1.4 2.4 0.8 0.8 2.0 1.2 0.0 0.8 0.8 1.0 1.0 0.0 0.8 1.4 0.8 1.7 3.4 2.9 0.8 0.8 3.4 1.2 68.1 0.8 0.8 1.3 0.8 0.8 0.9 1.1 0.6 0.1 0.1 0.7 0.3 2.3 0.1 2.3 2.3 6.0 3.5 0.0 1.2 5.4 0.7 1.1 0.0 0.0 0.5 1.2 1.2 0.9 0.0 1.0 3.7 0.0 0.0 0.0 3.5 7.2 2.7 9.8 3.7 4.4 1.1 3.4 0.1 0.9 0.0 1.3 6.3 0.0 4.6 3.1 5.8 0.0 0.6 1.4 1.5 1.5 0.4 1.2 1.9 1.7 4.4 0.0 1.9 1.8 3.8 0.8 2.8 4.1 4.4 1.9 2.7 2.9 2.1 3.4 3.0 2.4 8.5 2.8 1.8 3.7 3.9 0.5 0.0 0.1 0.0 1.1 0.7 0.0 0.0 0.2 0.0 0.1 0.6 2.3 0.9 0.1 0.3 0.5 0.0 0.0 0.1 0.8 0.8 3.9 0.8 0.8 0.0 0.8 0.8 1.0 0.8 0.0 0.3 0.0 0.4 0.1 0.1 0.3 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.2 242.3 0.0 0.0 0.0 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 839.4 8.6 0.0 0.0 0.0 0.3 0.9 0.2 0.0 8.9 0.6 1.4 6.5 0.0 10.3 3.8 0.0 0.2 0.0 0.2 0.2 TSSK4 "C14orf20, STK22E" ENSG00000139908 "Testis specific serine kinase 4" Q6SA08 14 24205697-24208362 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 46.1" "Cell type enriched" "Detected in some" 15 "Early spermatids: 178.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060660, HPA077103" Approved Approved "Cell Junctions" NA NA "Cell Junctions" "HPA060660: AB_2684339, HPA077103: AB_2732332" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.52e-1)" "unprognostic (5.69e-2)" "unprognostic (2.36e-1)" "unprognostic (3.38e-5)" "unprognostic (1.06e-1)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-3)" "unprognostic (3.42e-1)" "unprognostic (4.30e-2)" "unprognostic (6.28e-2)" "unprognostic (8.98e-2)" "unprognostic (7.26e-2)" 0.6 0.9 0.6 1.7 0.6 3.1 0.6 1.5 1.8 0.6 0.6 0.6 0.6 1.5 0.8 0.9 1.4 0.8 1.7 0.6 0.6 0.4 0.6 0.6 0.8 2.8 0.6 0.6 0.8 0.9 0.0 0.6 0.6 0.6 0.6 0.0 0.6 1.4 0.6 1.0 4.7 1.6 0.6 0.6 1.5 0.6 46.1 0.6 0.6 1.4 0.6 0.6 1.0 0.6 2.1 1.7 2.0 1.0 1.8 2.0 0.7 1.0 4.1 4.0 1.5 0.1 0.0 4.3 1.6 0.1 0.0 0.0 2.1 3.7 3.1 0.9 0.1 0.8 3.8 0.0 0.1 0.0 1.6 3.1 3.5 4.8 3.0 0.0 1.5 3.8 0.0 0.0 0.0 0.6 3.6 0.1 3.7 1.3 2.0 0.0 3.8 3.6 1.7 0.7 0.9 3.2 3.0 1.6 2.7 0.0 5.3 2.2 2.1 2.7 2.5 0.8 1.8 1.6 1.8 1.4 2.9 1.8 3.8 1.3 4.3 4.8 4.8 1.0 2.8 0.9 0.0 1.0 2.0 2.0 1.0 0.7 2.0 1.6 1.6 0.6 2.1 1.6 1.7 2.0 1.8 0.9 1.7 0.7 0.7 0.6 0.6 1.5 0.6 0.6 0.4 0.6 0.6 0.6 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 178.8 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.1 0.0 0.0 0.0 TSSK6 "CT72, FLJ24002, SSTK" ENSG00000178093 "Testis specific serine kinase 6" Q9BXA6 19 19512418-19515685 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "testis: 50.8" "Cell type enriched" "Detected in some" 5 "Late spermatids: 5597.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (2.12e-1)" "unprognostic (7.89e-2)" "unprognostic (7.26e-2)" "unprognostic (6.64e-2)" "unprognostic (3.39e-1)" "unprognostic (7.20e-5)" "unprognostic (3.38e-1)" "unprognostic (5.51e-3)" "unprognostic (5.17e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-4)" "unprognostic (2.28e-2)" "unprognostic (5.34e-3)" "unprognostic (2.74e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-3)" "unprognostic (9.89e-2)" 0.9 1.2 1.0 1.2 1.5 1.3 1.0 0.9 1.9 0.9 1.1 2.2 1.6 2.1 0.9 3.7 1.1 1.1 1.0 0.7 1.2 0.8 1.8 2.2 0.7 1.2 2.5 1.0 0.9 3.3 1.1 1.0 0.6 1.3 1.4 0.6 0.9 1.3 1.0 1.0 2.7 1.9 1.2 1.9 2.1 1.7 50.8 1.7 3.1 2.0 0.1 1.7 1.1 1.0 3.1 1.0 2.2 0.7 0.4 3.8 0.8 1.6 2.7 0.1 1.1 0.4 1.0 8.0 1.1 0.5 0.6 0.3 4.2 1.3 1.4 2.0 0.0 0.5 1.4 0.5 1.1 0.2 1.0 1.9 0.7 1.7 0.9 1.2 0.9 3.2 0.6 1.0 0.6 1.9 0.6 0.3 5.4 1.9 0.8 0.0 0.5 3.4 2.0 3.7 0.8 4.4 2.7 0.7 1.2 0.1 0.5 0.6 2.9 1.6 0.4 1.4 0.4 2.6 0.7 0.3 2.0 0.6 3.9 1.7 3.5 1.4 0.8 2.2 1.2 1.9 0.0 0.6 2.2 0.8 0.2 1.1 3.1 1.7 2.0 0.3 1.9 3.8 2.1 1.1 0.4 0.7 1.0 1.0 0.8 1.0 1.5 0.9 1.9 1.2 0.8 2.5 1.0 1.3 1.7 0.0 0.0 0.0 0.2 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1053.4 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.3 0.6 5597.9 44.3 0.0 1.7 0.0 0.0 0.0 0.1 0.0 53.7 0.1 0.0 19.4 0.6 51.3 21.7 0.1 0.1 0.0 0.0 0.0 TTBK1 KIAA1855 ENSG00000146216 "Tau tubulin kinase 1" Q5TCY1 6 43243680-43288259 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9" "Cell type enhanced" "Detected in some" 17 "Bipolar cells: 6.7;Horizontal cells: 4.8;Proximal tubular cells: 1.9" "Cancer enhanced" "Detected in some" "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "SCLC-21H: 21.3;SH-SY5Y: 8.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031735, HPA031736" Enhanced Supported Nucleoplasm,Cytosol NA NA Cytosol Nucleoplasm "HPA031735: AB_2674019, HPA031736: AB_10670294" "unprognostic (1.68e-1)" "unprognostic (7.88e-3)" "unprognostic (7.01e-2)" "unprognostic (1.62e-3)" "unprognostic (2.18e-1)" "unprognostic (2.24e-4)" "unprognostic (2.46e-3)" "unprognostic (3.01e-2)" "unprognostic (3.09e-1)" "unprognostic (1.85e-1)" "unprognostic (3.01e-2)" "unprognostic (2.12e-4)" "unprognostic (7.42e-2)" "unprognostic (3.68e-1)" "unprognostic (1.32e-1)" "unprognostic (2.64e-3)" "unprognostic (3.04e-4)" 1.1 3.9 12.4 1.3 12.9 0.9 1.0 14.9 28.9 1.0 1.4 8.2 0.0 4.6 1.0 1.0 1.0 1.1 1.4 1.3 10.3 7.5 1.7 3.5 1.1 1.2 7.1 12.5 1.0 1.4 1.6 7.7 1.0 9.0 1.3 1.3 0.7 1.0 1.2 1.0 1.0 6.8 1.1 6.2 1.2 1.3 2.3 8.3 0.0 1.0 0.0 1.3 1.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.0 21.3 8.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 12.4 12.9 14.9 21.7 10.3 7.5 7.1 12.5 9.0 8.3 0.0 0.0 0.0 0.0 0.0 6.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.1 4.8 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.9 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 TTBK2 "KIAA0847, SCA11" ENSG00000128881 "Tau tubulin kinase 2" Q6IQ55 15 42738734-42920809 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.8" "Cell type enhanced" "Detected in many" 7 "Early spermatids: 69.2;Late spermatids: 113.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018113, HPA049866" Approved Uncertain "Intermediate filaments" NA NA "Intermediate filaments" "HPA018113: AB_1858421, HPA049866: AB_2680923" "unprognostic (2.15e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (7.73e-2)" "unprognostic (4.26e-1)" "unprognostic (6.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.78e-2)" "unprognostic (8.62e-2)" "unprognostic (3.46e-2)" "unprognostic (7.29e-2)" "unprognostic (3.63e-2)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" 6.7 7.3 8.7 5.1 14.0 8.0 6.0 17.8 22.0 7.0 7.2 10.9 3.8 3.3 8.5 6.2 4.2 7.8 6.2 10.7 9.4 11.5 6.1 4.3 6.1 5.5 11.1 14.8 11.5 3.3 9.0 13.9 8.8 24.7 8.2 5.6 7.6 4.8 6.5 11.6 6.3 4.6 8.4 10.9 7.1 4.9 41.8 10.8 3.6 6.7 1.9 5.4 6.8 8.7 2.5 1.4 1.3 3.0 2.1 3.1 0.7 6.2 3.4 9.3 4.9 6.4 6.6 1.9 5.1 7.3 4.4 6.6 4.6 1.5 4.0 6.5 4.9 8.9 4.2 8.1 6.0 6.8 13.0 5.7 5.0 7.7 1.9 5.0 7.1 8.6 5.2 6.2 4.0 21.0 9.6 5.5 5.4 7.5 6.5 4.2 0.8 4.7 5.0 2.6 1.5 3.8 7.9 8.8 2.0 5.6 3.8 6.9 7.8 12.5 0.9 2.6 6.7 3.2 8.8 6.7 5.7 5.7 7.1 7.1 7.6 10.1 6.0 4.2 5.5 3.6 0.4 3.0 1.2 1.7 1.4 3.1 1.5 1.6 1.3 0.8 2.5 2.1 1.5 1.3 2.1 1.5 1.4 0.5 0.7 8.7 14.0 17.8 22.0 9.4 11.5 11.1 14.8 24.7 10.8 6.0 10.2 7.4 11.8 9.5 31.0 14.2 15.3 33.5 9.1 8.7 35.3 3.5 0.0 4.9 69.2 12.8 3.6 23.3 3.7 2.6 13.1 11.0 18.5 6.8 6.4 42.9 13.7 12.9 13.9 113.0 15.5 15.4 11.8 9.0 4.9 15.0 6.5 2.9 19.1 4.5 38.8 12.9 18.9 39.4 7.1 8.2 2.6 8.7 5.2 5.5 TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.3;testis: 31.7" "Cell type enhanced" "Detected in many" 15 "Early spermatids: 19.9;Erythroid cells: 23.3;Spermatocytes: 63.4;Spermatogonia: 28.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "T-reg: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010166, CAB013229" Enhanced Approved Nucleoli,Cytosol NA Yes "Nucleoli, Cytosol" "CAB010166: AB_632567, CAB013229: AB_2533230" "unprognostic (4.27e-2)" "unprognostic (8.71e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (1.44e-5)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.84e-10)" "unprognostic (1.56e-3)" "unprognostic (7.95e-2)" "unprognostic (2.02e-3)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.54e-1)" "unprognostic (0.00e+0)" "unprognostic (3.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" 1.1 1.4 0.3 3.2 0.4 13.9 1.0 0.3 0.4 1.0 2.7 0.2 0.2 2.2 0.5 1.0 6.5 0.3 0.4 1.5 0.4 0.3 0.9 0.6 1.2 4.6 0.4 0.2 0.4 0.5 0.0 0.3 3.0 0.6 0.6 3.6 0.3 1.2 0.6 0.3 2.0 2.8 0.7 0.8 2.1 1.8 31.7 0.2 58.3 0.5 2.6 5.4 0.8 1.8 1.7 0.0 1.1 0.0 1.1 4.0 0.8 13.3 8.0 24.0 19.6 1.1 3.5 13.6 15.5 9.5 22.7 27.8 10.9 10.2 19.8 12.1 6.6 23.8 17.3 21.1 9.5 31.6 18.0 17.0 18.3 10.6 8.9 0.0 21.5 11.9 0.4 1.0 15.8 10.1 3.3 12.8 27.9 19.9 20.4 19.2 9.9 12.2 15.5 14.1 12.0 9.7 11.0 43.8 8.2 5.7 8.6 16.5 9.7 9.1 9.9 5.6 13.5 9.3 16.3 5.3 10.2 10.2 6.6 24.7 4.6 15.5 11.0 3.6 20.0 8.7 0.0 0.0 1.1 0.6 0.0 0.6 0.9 1.0 1.6 0.0 1.7 0.3 0.5 0.3 1.1 0.0 0.0 4.0 0.8 0.3 0.4 0.3 0.4 0.4 0.3 0.4 0.2 0.6 0.2 3.0 0.6 0.0 0.5 1.1 0.0 0.7 0.0 4.0 3.4 0.0 2.0 4.1 3.3 0.4 19.9 0.1 0.2 23.3 0.2 13.1 0.8 0.2 1.1 0.0 5.2 0.0 1.7 0.0 2.4 12.8 0.9 1.2 0.0 9.0 1.0 0.3 0.4 0.0 0.7 0.0 1.2 6.5 0.2 63.4 28.5 0.3 3.1 0.0 1.2 0.7 TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease mutation, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 136.5;skeletal muscle: 713.8;tongue: 227.0" "Cell type enriched" "Detected in many" 134 "Cardiomyocytes: 19161.7" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 4.9" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced NA NA 25000000 "CAB022682: , HPA007042: AB_1080292, HPA030048: AB_2732451" "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" 23.7 0.3 0.2 0.3 0.3 0.9 0.3 0.2 0.4 0.2 0.2 0.0 0.0 0.2 0.2 21.3 8.3 0.2 0.3 136.5 0.2 0.2 0.2 0.2 0.4 0.4 0.2 0.0 0.3 0.4 0.2 0.3 0.3 0.0 0.7 0.2 0.0 11.6 0.2 713.8 0.3 0.2 0.2 0.3 0.3 0.2 0.4 0.0 0.0 5.6 227.0 15.8 0.3 0.2 7.0 0.3 1.9 0.3 5.0 7.3 0.1 0.7 0.3 1.9 1.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 1.8 0.3 2.4 0.6 0.0 1.8 1.8 0.0 0.0 0.0 2.4 2.0 3.7 2.7 1.1 0.0 0.3 0.8 2.4 0.0 0.0 0.0 1.7 1.4 1.8 2.2 1.2 0.4 0.4 1.6 2.5 0.4 0.2 1.8 1.3 4.9 1.3 0.0 0.6 1.1 1.7 0.4 1.3 0.0 1.7 0.8 2.4 1.6 0.0 0.0 0.9 0.4 3.6 0.4 3.5 0.1 1.1 0.9 1.9 0.3 0.7 0.5 0.2 0.2 6.9 1.2 0.9 0.2 7.0 2.7 3.5 1.3 5.0 0.2 0.3 7.3 0.1 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 14.9 142.6 2.2 0.2 0.8 28.9 19161.7 17.8 5.3 11.4 0.0 19.6 0.4 1.7 7.7 35.3 0.7 0.0 0.0 23.6 0.2 0.5 0.1 9.3 0.5 0.2 15.9 4.1 2.5 0.0 4.3 1.1 0.4 0.0 0.0 0.0 10.3 0.9 0.0 4.2 0.0 26.3 0.0 1.4 5.7 0.2 0.1 0.3 4.9 0.0 0.0 TXK "BTKL, PSCTK5, PTK4, RLK, TKL" ENSG00000074966 "TXK tyrosine kinase" P42681 4 48066393-48134256 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood: 43.5;lymphoid tissue: 49.1;placenta: 28.4" "Cell type enriched" "Detected in some" 9 "T-cells: 43.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "NK-cell: 43.5" "Group enriched" "Detected in many" 26 "NK-cells: 43.5;T-cells: 17.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.8;HMC-1: 11.3;U-266/70: 5.5;U-266/84: 6.8;WM-115: 25.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062482 Approved Vesicles NA NA Vesicles "HPA062482: AB_2684778" "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (9.24e-3)" "unprognostic (1.09e-2)" "unprognostic (2.58e-4)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (1.50e-1)" "unprognostic (6.39e-3)" "unprognostic (8.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (2.59e-1)" "unprognostic (2.04e-2)" 1.8 1.5 0.3 15.3 0.4 3.9 1.5 0.2 0.6 0.8 2.1 0.3 0.2 1.3 1.3 11.6 2.4 2.6 1.7 0.7 0.2 0.4 2.1 2.8 4.0 49.1 0.5 0.5 0.5 1.0 0.4 1.3 28.4 0.6 0.9 1.0 1.0 6.1 0.2 0.5 1.7 7.9 0.4 0.4 17.8 1.0 1.7 0.2 14.0 1.9 0.2 19.3 2.4 1.4 0.0 0.1 1.1 0.0 43.5 17.5 10.6 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 4.8 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.4 0.2 0.1 2.4 0.0 0.0 0.0 0.3 11.3 0.0 0.0 0.1 0.0 0.8 0.1 0.4 0.2 0.0 0.7 0.0 0.0 2.1 0.0 0.6 0.8 0.3 0.0 0.0 1.4 1.3 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.2 0.4 0.0 0.0 0.3 0.1 5.5 6.8 0.4 0.0 0.4 25.4 1.1 0.0 0.3 13.2 0.0 17.4 0.0 6.8 6.4 0.0 0.0 17.5 11.9 0.8 43.5 0.0 0.1 5.1 10.6 0.3 0.4 0.2 0.6 0.2 0.4 0.5 0.5 0.6 0.2 0.0 2.6 0.8 0.5 0.3 0.0 0.2 2.5 0.0 0.0 0.0 3.9 0.2 1.7 1.3 4.3 0.1 0.0 0.0 0.0 0.1 0.5 0.4 1.1 1.0 1.2 0.0 0.0 4.3 5.1 1.3 0.3 0.5 1.7 0.0 0.0 2.3 0.2 0.0 0.0 0.6 0.4 0.0 0.0 0.4 0.2 1.0 0.5 43.1 0.2 0.6 TYK2 JTK1 ENSG00000105397 "Tyrosine kinase 2" P29597 19 10350529-10380676 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Distal tubular cells: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 63.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005157 Uncertain Approved Cytosol NA NA Cytosol "HPA005157: AB_1858480" "unprognostic (1.60e-2)" "unprognostic (6.12e-3)" "unprognostic (3.67e-2)" "prognostic favorable (9.62e-4)" "unprognostic (7.61e-2)" "prognostic favorable (1.05e-5)" "unprognostic (1.20e-2)" "unprognostic (6.16e-3)" "unprognostic (4.93e-2)" "unprognostic (1.90e-2)" "prognostic favorable (1.02e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (2.10e-3)" "unprognostic (1.78e-1)" "unprognostic (4.19e-1)" "prognostic favorable (4.16e-4)" 16.8 19.0 22.9 36.0 22.6 49.4 17.5 24.4 23.9 17.8 19.4 26.7 13.9 20.0 19.3 20.2 15.0 16.8 21.8 17.0 18.3 14.0 24.0 34.4 27.5 31.5 24.7 17.4 20.0 21.3 19.0 24.8 13.9 19.1 21.1 18.6 21.6 24.4 15.4 15.6 24.4 23.8 16.7 17.9 47.9 18.5 6.4 22.8 33.9 20.9 13.5 34.7 16.7 15.1 5.8 15.8 22.9 13.4 5.3 9.1 7.3 8.6 12.7 7.6 11.9 10.1 14.3 7.3 11.9 12.2 15.1 16.7 9.7 5.8 13.2 14.1 13.3 10.4 8.8 9.2 14.0 8.0 23.3 14.2 24.4 25.3 23.9 15.9 10.2 28.2 13.8 9.9 17.2 10.2 9.5 14.6 17.5 10.2 37.0 13.3 27.3 15.0 63.2 2.4 8.6 22.2 15.0 6.5 13.5 12.3 28.0 7.2 8.8 11.6 12.3 8.5 6.2 6.8 17.4 12.4 20.4 7.3 23.5 14.0 30.5 23.7 12.1 10.2 21.4 11.4 6.6 13.4 17.0 9.1 10.2 5.9 5.6 5.5 8.1 15.8 5.8 3.8 5.1 22.9 5.3 9.7 9.0 6.8 7.3 22.9 22.6 24.4 23.9 18.3 14.0 24.7 17.4 19.1 22.8 11.9 19.9 6.7 4.8 6.0 8.4 23.6 12.7 5.3 10.3 8.7 3.9 6.0 44.7 6.5 1.4 7.5 10.2 0.0 9.5 6.9 9.4 5.5 18.5 20.2 13.0 0.0 4.6 14.1 30.7 6.4 6.9 18.0 15.1 15.4 8.3 7.4 9.1 11.5 9.2 19.5 9.7 0.0 8.6 1.4 4.3 6.4 5.6 19.2 9.0 4.9 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583586 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.2;ovary: 48.2" "Cell type enhanced" "Detected in many" 9 "Leydig cells: 41.1;Peritubular cells: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 5.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.0" "Cell line enhanced" "Detected in many" "BEWO: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 6400000 "HPA071245: AB_2686371" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 18.3 4.1 18.7 2.1 16.6 1.5 7.7 27.3 39.2 2.3 1.8 25.6 1.2 2.3 5.0 4.2 12.7 11.7 3.1 2.5 15.1 7.8 6.4 1.6 3.2 1.9 19.6 18.2 48.2 9.5 1.3 0.8 5.9 14.0 3.3 1.7 1.7 2.4 6.7 1.4 13.0 2.9 4.8 23.1 5.4 3.6 17.9 16.6 0.0 1.8 2.2 4.1 2.9 2.8 1.2 1.0 5.0 0.9 1.0 0.8 0.2 4.8 3.2 10.1 11.0 9.5 6.4 33.9 7.0 4.5 7.0 6.5 17.8 1.6 0.1 9.0 5.6 9.8 11.4 11.2 1.7 3.2 2.7 7.5 1.4 10.1 8.5 6.6 2.4 0.2 2.0 3.6 5.3 1.8 2.8 5.1 4.7 8.8 2.1 3.8 4.6 1.1 0.4 23.2 7.5 3.2 14.9 9.1 1.8 0.6 9.3 12.1 3.4 6.5 10.5 7.8 15.3 8.6 2.8 4.0 13.9 6.1 10.2 10.5 0.8 1.6 1.4 8.4 16.0 8.3 2.6 0.9 0.8 0.6 0.5 0.6 0.7 0.6 0.8 0.3 1.2 0.7 0.7 5.0 1.0 0.5 1.0 0.5 0.2 18.7 16.6 27.3 32.7 15.1 7.8 19.6 18.2 14.0 16.6 3.0 1.4 0.9 6.2 6.1 1.2 3.7 2.5 0.0 0.0 3.5 5.9 2.4 0.0 3.4 2.7 4.9 0.9 0.0 3.1 8.9 5.6 4.8 0.0 0.2 1.0 0.0 1.7 12.3 0.6 4.0 41.1 1.1 8.5 0.0 0.1 6.5 3.7 0.0 44.2 1.5 3.9 0.0 2.8 2.4 5.4 9.5 15.8 0.0 1.6 4.7 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529629 "Enzymes, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071190 Approved "Nucleoplasm,Golgi apparatus,Midbody" Yes No "Nucleoplasm, Golgi apparatus" Midbody "HPA071190: AB_2686358" "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 21.6 22.0 23.5 18.9 26.2 30.1 23.5 10.8 30.5 14.3 16.3 17.2 30.8 16.3 11.5 12.9 16.0 12.9 12.1 11.4 27.0 31.8 27.9 32.4 16.9 24.3 30.6 20.3 12.1 11.8 25.0 12.5 16.5 33.4 14.7 17.4 14.1 15.9 22.9 30.6 11.5 21.8 9.6 20.5 21.3 16.8 10.4 14.1 23.0 17.1 11.7 24.1 16.1 12.8 5.7 4.3 4.5 9.2 5.9 8.5 4.0 21.1 9.9 5.2 12.7 14.9 11.8 11.7 28.0 15.3 23.0 16.6 6.4 13.3 17.3 24.5 20.9 11.2 12.3 9.9 15.5 37.1 23.7 7.2 17.1 12.3 5.8 11.5 24.9 20.0 12.1 16.4 22.6 21.7 16.1 13.2 12.0 14.9 24.1 39.4 8.9 13.2 6.6 6.9 15.9 13.4 8.5 23.3 14.4 15.3 21.9 9.5 8.8 24.7 23.0 18.0 7.5 19.9 28.0 20.5 26.3 14.9 18.1 39.0 25.0 34.7 20.5 21.9 12.2 23.8 4.5 3.3 3.7 8.2 8.6 8.5 5.4 6.2 6.8 3.6 5.7 6.3 7.1 2.0 5.9 9.2 4.3 4.9 4.0 23.5 26.2 10.8 30.5 27.0 31.8 30.6 20.3 33.4 14.1 17.9 32.1 50.1 25.7 26.2 21.7 29.4 56.0 41.5 50.0 50.6 11.8 22.6 48.0 23.2 35.7 30.8 40.7 0.0 20.2 32.6 19.3 44.8 45.0 71.0 27.6 22.3 32.1 35.0 64.6 34.6 19.8 51.7 27.0 44.1 35.0 13.6 28.8 34.8 18.4 49.4 21.6 0.0 27.3 23.4 22.0 21.5 18.8 52.2 31.1 52.1 ULK1 "ATG1, ATG1A" ENSG00000177169 "Unc-51 like autophagy activating kinase 1" O75385 12 131894651-131923167 "Enzymes, Plasma proteins, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 7 "Horizontal cells: 50.9;Rod photoreceptor cells: 87.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "neutrophil: 6.9;plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063990 Approved Cytosol NA NA Cytosol "HPA063990: AB_2685167" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (2.52e-3)" "unprognostic (2.21e-3)" "unprognostic (8.01e-3)" "unprognostic (5.48e-2)" "unprognostic (2.74e-2)" "unprognostic (5.04e-3)" "unprognostic (3.94e-3)" "unprognostic (2.03e-2)" "unprognostic (9.09e-3)" "unprognostic (8.19e-2)" "unprognostic (6.25e-2)" "unprognostic (2.38e-1)" "unprognostic (2.75e-1)" "unprognostic (1.82e-2)" "unprognostic (3.16e-1)" 10.9 18.6 14.6 9.2 49.6 33.2 8.9 24.0 24.4 14.4 11.8 6.9 13.3 11.7 16.5 10.7 9.8 10.6 16.2 17.4 11.5 8.3 9.0 15.8 9.0 8.3 7.9 12.0 18.2 59.6 13.8 23.8 17.2 11.6 13.4 4.0 13.9 18.1 13.4 33.4 24.3 11.5 10.2 5.4 16.5 11.4 11.4 11.4 13.8 10.7 9.6 6.5 12.1 10.9 0.6 6.4 6.9 1.7 0.2 0.8 0.6 5.2 16.9 7.8 9.7 3.5 2.9 10.7 8.3 6.0 3.6 2.9 3.6 5.4 1.4 8.8 5.8 7.2 5.2 1.7 3.3 1.0 5.6 10.2 3.5 13.8 4.9 6.6 2.5 7.8 5.3 9.1 3.9 1.6 9.9 4.4 10.8 4.6 4.2 2.3 11.9 15.6 14.7 8.6 2.4 16.2 11.8 2.8 6.9 2.1 6.5 19.9 11.0 8.9 9.2 4.6 8.3 13.9 17.1 8.3 8.5 5.1 14.8 3.8 18.6 6.7 1.9 14.4 4.4 9.8 0.2 1.7 2.3 0.8 0.7 0.2 0.1 0.7 0.7 0.3 0.6 0.5 0.5 6.9 0.2 0.7 6.4 0.5 0.6 14.6 49.6 24.0 24.4 11.5 8.3 7.9 12.0 11.6 11.4 14.9 16.7 11.8 5.7 12.8 23.0 18.0 17.8 4.0 11.4 7.0 37.3 4.0 1.7 8.0 0.7 12.0 5.2 0.0 10.9 2.6 9.3 12.0 3.5 23.1 4.8 50.9 18.4 6.2 11.9 1.9 11.5 5.4 5.0 3.6 15.4 12.6 18.3 7.0 14.9 2.4 87.3 12.9 10.3 3.9 5.9 16.9 14.4 8.3 8.3 6.9 ULK2 "ATG1B, KIAA0623, Unc51.2" ENSG00000083290 "Unc-51 like autophagy activating kinase 2" Q8IYT8 17 19770829-19867936 "Enzymes, Predicted intracellular proteins" "Autophagy, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Late spermatids: 51.2;Spermatocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "intermediate monocyte: 6.9;non-classical monocyte: 5.8" "Lineage enriched" "Detected in many" 4 "monocytes: 6.9" "Cell line enhanced" "Detected in many" "SuSa: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037021 Approved NA NA "CAB037021: AB_1841237" "unprognostic (1.47e-1)" "unprognostic (1.88e-1)" "unprognostic (2.56e-1)" "unprognostic (1.03e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-1)" "unprognostic (6.53e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.11e-3)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-1)" "unprognostic (1.38e-2)" 10.3 7.1 15.5 4.4 19.1 2.8 7.6 15.5 21.8 9.3 7.2 28.3 6.7 3.1 9.5 8.4 6.8 11.5 7.7 8.3 15.0 10.9 7.0 3.7 8.8 4.6 15.8 12.0 12.4 7.5 14.2 4.2 8.5 15.9 9.0 4.8 8.5 5.3 11.0 13.5 7.8 3.6 9.9 28.3 7.1 5.5 33.0 14.6 2.0 7.0 1.4 3.8 7.7 6.3 0.1 1.4 0.5 6.9 0.4 1.6 0.6 7.5 7.8 11.2 1.5 6.6 12.4 0.0 6.3 7.8 6.6 6.2 0.1 1.6 0.0 3.3 8.1 7.5 3.6 0.0 1.3 6.3 6.2 8.1 0.2 3.3 0.0 8.6 0.0 3.8 8.0 9.8 3.3 2.8 5.8 4.6 0.0 0.0 0.0 5.5 2.1 0.0 0.3 1.6 0.1 2.0 0.4 0.0 0.0 4.8 3.3 2.8 11.7 9.9 1.3 3.5 29.0 7.7 2.9 7.3 0.0 1.0 2.4 3.8 0.0 0.0 0.0 1.0 0.0 2.3 0.0 1.5 0.3 0.6 6.9 0.2 0.1 1.0 1.0 1.4 0.1 1.6 1.0 0.5 0.4 5.8 0.1 0.2 0.6 15.5 19.1 15.5 21.8 15.0 10.9 15.8 12.0 15.9 14.6 17.9 10.2 0.0 4.2 6.5 15.9 9.5 7.6 8.1 7.9 7.0 7.9 6.4 3.3 3.0 27.9 2.9 0.7 0.0 2.9 2.6 9.0 6.0 0.0 1.7 7.1 14.3 2.4 3.7 16.1 51.2 13.0 5.1 8.5 4.6 3.2 5.6 2.3 3.2 11.7 4.5 10.6 12.9 11.3 38.8 20.5 8.4 2.4 3.8 2.1 3.4 ULK3 "DKFZP434C131, FLJ90566" ENSG00000140474 "Unc-51 like kinase 3" Q6PHR2 15 74836116-74843346 "Enzymes, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 6 "Bipolar cells: 75.1;Horizontal cells: 84.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040474 Approved NA NA "HPA040474: AB_2677003" "unprognostic (3.67e-2)" "unprognostic (8.90e-3)" "unprognostic (2.65e-3)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (2.07e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (1.47e-2)" "unprognostic (4.18e-2)" "prognostic favorable (7.47e-4)" "unprognostic (1.97e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-2)" "unprognostic (1.63e-1)" "unprognostic (1.16e-1)" "unprognostic (4.97e-3)" 7.0 11.7 11.8 8.4 15.4 2.9 7.4 21.3 20.4 7.9 13.8 9.0 9.0 7.9 5.3 9.5 33.9 6.7 9.6 14.1 11.8 8.9 13.4 9.3 6.4 7.9 11.2 15.3 4.9 14.7 12.1 12.3 5.7 21.1 8.2 14.4 10.4 10.4 7.4 19.1 24.6 20.3 7.2 5.8 9.9 11.1 6.0 7.6 4.2 6.1 10.9 13.7 8.6 10.6 3.8 4.2 3.8 7.8 5.8 12.6 4.9 3.9 10.7 5.6 9.7 6.4 4.2 3.7 3.1 4.5 6.5 7.1 4.2 8.9 8.5 6.0 3.5 7.5 4.0 15.6 4.3 2.7 16.2 15.4 25.2 13.6 5.1 9.3 6.0 16.2 5.5 8.6 5.7 5.4 2.4 9.8 11.8 6.9 9.2 5.3 5.8 4.4 6.2 6.2 9.3 5.5 13.0 6.8 16.1 4.2 5.0 10.4 13.2 6.1 5.8 19.3 5.9 8.4 15.1 5.5 8.7 5.6 8.6 6.7 12.8 11.6 6.2 4.9 17.7 7.5 3.8 3.6 1.4 12.6 7.8 10.1 3.8 7.4 10.3 4.0 3.5 8.1 5.5 0.9 5.8 6.2 4.2 9.7 4.9 11.8 15.4 21.3 20.4 11.8 8.9 11.2 15.3 21.1 7.6 8.9 11.7 3.7 6.8 9.0 75.1 15.1 7.6 2.7 2.3 12.2 15.7 7.1 16.6 9.2 0.8 8.4 42.8 0.0 10.2 2.5 7.3 8.4 20.7 11.0 13.7 84.2 10.9 13.5 6.3 1.5 12.0 6.5 5.0 19.0 17.8 18.4 10.1 16.4 11.0 13.3 54.3 0.0 7.6 9.4 19.8 19.1 4.8 17.0 20.4 7.2 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962430 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 279.5;Late spermatids: 329.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 4.3 4.8 5.1 4.7 8.3 10.3 4.2 4.3 5.4 11.9 2.8 5.9 6.0 2.1 10.7 10.9 2.8 12.3 3.1 13.1 5.2 3.0 5.4 3.4 5.5 4.2 3.1 4.2 4.5 3.6 13.5 19.7 9.0 5.8 4.4 2.8 6.7 4.2 4.5 1.4 3.5 3.3 5.1 5.7 4.4 3.4 27.5 3.4 6.3 7.1 1.7 8.4 4.0 6.0 6.4 5.1 10.7 6.3 2.6 10.3 5.2 7.3 1.7 2.7 3.0 1.1 1.7 4.6 2.5 2.6 3.1 2.6 0.9 2.2 8.6 1.4 5.8 3.0 3.7 3.2 1.9 2.8 1.1 0.9 1.6 5.4 2.9 3.9 5.6 1.7 1.6 2.2 15.0 3.1 3.9 2.1 5.9 1.9 7.2 2.2 5.9 7.0 4.5 3.3 1.8 3.1 1.6 8.5 3.7 6.5 7.1 1.4 9.9 2.6 1.2 2.1 1.8 3.0 1.8 6.2 2.0 2.2 13.2 2.1 4.3 8.0 3.6 11.0 5.9 2.4 5.7 5.8 5.8 8.0 6.3 6.5 5.6 8.6 7.2 5.1 6.4 6.5 9.2 10.7 2.6 3.2 4.6 10.3 5.2 5.1 8.3 4.3 5.4 5.2 3.0 3.1 4.2 5.8 3.4 8.9 5.8 1.9 2.8 1.8 5.4 12.8 5.1 53.5 4.5 3.5 51.1 2.8 0.0 2.3 279.5 4.4 1.1 0.0 2.1 3.9 3.3 1.2 1.1 5.9 6.5 11.1 1.7 1.8 4.1 329.6 6.1 5.6 0.0 6.4 1.1 11.2 2.8 0.0 3.9 5.0 25.1 6.5 3.3 29.9 8.7 3.1 3.5 4.4 1.7 0.8 VRK1 ENSG00000100749 "Vaccinia related kinase 1" Q99986 14 96797304-96931722 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 39.0" "Cell type enhanced" "Detected in many" 8 "Erythroid cells: 93.5;Spermatocytes: 141.1;Spermatogonia: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No Nucleoplasm Cytosol "HPA000660: AB_1080579, HPA017929: AB_1858770" "unprognostic (1.03e-1)" "unprognostic (1.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.24e-3)" "unprognostic (5.42e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" "unprognostic (5.47e-2)" "unprognostic (5.14e-2)" "unprognostic (1.60e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (4.56e-2)" "unprognostic (3.36e-2)" "unprognostic (1.58e-1)" 6.0 4.4 7.1 9.8 17.1 39.0 8.7 8.6 10.2 6.1 7.8 4.4 4.1 5.2 5.9 5.7 9.4 6.9 3.3 6.0 7.4 6.5 6.2 4.3 4.5 18.3 6.9 6.1 5.9 3.7 3.8 5.1 7.1 6.7 5.3 9.1 4.1 4.8 4.1 4.3 6.4 6.9 5.4 6.1 15.7 6.7 33.3 6.9 33.0 4.9 6.1 18.4 5.9 5.7 20.8 13.5 20.1 9.5 28.5 22.3 12.5 15.8 9.1 22.7 10.1 2.7 5.0 14.1 12.0 9.3 19.2 19.2 10.9 15.8 40.4 8.1 7.1 11.8 17.6 21.2 15.7 26.5 23.0 11.3 25.1 6.0 11.1 3.0 48.4 15.8 2.7 2.8 14.5 10.6 3.9 13.3 31.0 21.4 25.6 16.5 18.1 38.4 20.8 14.5 12.1 17.5 36.0 39.7 13.7 8.8 16.4 16.0 9.1 10.6 10.8 8.1 11.9 12.4 19.2 7.1 8.8 7.8 15.1 12.0 13.4 15.8 39.1 13.7 21.2 10.4 20.1 7.6 14.5 15.1 9.3 18.4 20.3 17.6 18.5 9.9 20.8 19.1 19.3 4.5 28.5 9.5 13.5 22.3 12.5 7.1 17.1 8.6 10.2 7.4 6.5 6.9 6.1 6.7 6.9 3.0 2.9 30.5 11.8 14.9 12.3 10.6 15.3 42.8 13.6 14.0 7.9 19.7 10.0 9.8 13.3 11.3 2.4 93.5 16.8 39.6 10.4 5.3 27.7 2.4 16.3 9.5 2.9 6.2 9.7 10.8 5.2 11.5 11.8 12.6 8.0 5.2 7.6 0.0 9.2 8.4 6.6 19.4 11.3 141.1 122.1 12.2 12.6 26.7 11.2 8.4 VRK2 ENSG00000028116 "Vaccinia related kinase 2" Q86Y07 2 57907651-58159920 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046459, HPA047503" Approved Supported "Endoplasmic reticulum" NA NA "Endoplasmic reticulum" "CAB046459: AB_1858773, HPA047503: AB_2680071" "unprognostic (1.87e-1)" "unprognostic (5.84e-2)" "unprognostic (4.65e-2)" "unprognostic (1.33e-3)" "unprognostic (1.27e-1)" "unprognostic (1.60e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (3.90e-2)" "unprognostic (4.76e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (3.48e-1)" "unprognostic (1.62e-1)" "unprognostic (2.99e-1)" "unprognostic (3.56e-1)" 18.7 17.7 10.9 21.9 28.3 14.9 16.1 2.4 15.1 15.6 13.5 27.3 16.3 9.9 18.4 16.7 26.8 13.2 10.9 21.6 14.4 8.9 12.4 15.2 15.6 19.5 29.2 13.5 14.2 20.0 16.1 18.7 16.1 18.7 15.7 15.6 9.3 20.5 17.6 21.5 12.8 12.9 20.1 19.0 20.1 13.5 12.5 31.2 13.6 17.4 16.7 23.0 18.1 19.4 19.7 17.0 21.6 21.3 11.3 12.2 9.2 14.2 9.5 1.1 6.3 7.1 13.1 19.7 13.2 13.2 9.1 9.3 19.4 15.1 17.4 17.4 11.6 15.0 10.9 13.8 14.4 13.7 31.2 9.3 19.6 7.7 13.8 11.3 16.6 11.7 7.2 17.2 14.6 21.1 10.9 26.2 2.4 19.2 11.2 15.2 8.2 0.1 12.7 12.0 22.6 4.8 19.0 4.8 11.8 15.1 11.7 3.8 0.1 20.9 12.5 10.5 10.9 8.8 10.2 14.6 0.2 30.3 8.2 0.2 16.5 13.0 9.3 7.4 20.6 15.0 13.7 16.8 21.6 10.1 21.3 12.2 19.7 9.8 11.8 16.6 19.0 7.4 9.5 6.0 11.3 20.6 17.0 11.5 9.2 10.9 28.3 2.4 15.1 14.4 8.9 29.2 13.5 18.7 31.2 20.8 9.1 14.1 11.3 8.8 1.0 17.1 10.2 30.8 15.9 17.4 0.0 19.7 13.3 22.0 16.8 15.0 2.9 46.7 22.8 18.5 8.5 8.1 16.3 6.8 17.1 0.0 6.3 4.9 17.7 6.5 5.5 21.4 10.1 49.5 4.3 4.6 21.8 7.8 5.6 7.1 3.6 6.5 13.7 8.3 12.6 7.3 16.2 12.7 7.1 12.2 VRK3 ENSG00000105053 "Vaccinia related kinase 3" Q8IV63 19 49976467-50025946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 77.2" "Group enriched" "Detected in all" 6 "Early spermatids: 469.4;Late spermatids: 1260.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056489 Approved Supported Nucleoplasm,Vesicles NA NA "Nucleoplasm, Vesicles" "HPA056489: AB_2683150" "unprognostic (2.09e-1)" "unprognostic (3.14e-2)" "unprognostic (1.26e-1)" "unprognostic (4.94e-3)" "unprognostic (1.23e-1)" "unprognostic (2.22e-3)" "unprognostic (9.78e-2)" "unprognostic (3.47e-1)" "unprognostic (8.79e-2)" "unprognostic (2.48e-1)" "unprognostic (1.31e-2)" "unprognostic (1.43e-1)" "prognostic favorable (1.83e-4)" "unprognostic (9.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.06e-1)" "prognostic favorable (5.66e-4)" 9.7 11.9 9.2 9.4 12.7 10.7 8.3 12.0 14.1 8.9 13.4 11.9 9.3 13.4 15.7 10.8 8.4 18.0 12.2 7.4 9.3 11.1 16.7 16.2 8.5 13.4 10.4 9.9 11.2 11.5 7.1 11.8 10.7 9.8 9.4 11.7 14.2 14.3 8.5 11.8 7.7 17.3 7.5 11.0 12.8 10.9 77.2 9.1 24.7 14.1 6.0 12.9 9.9 8.0 24.5 19.7 47.3 20.9 33.5 30.1 18.1 16.0 16.7 12.3 13.2 16.3 15.1 12.8 11.6 13.9 17.3 19.1 8.9 18.0 19.4 8.3 11.2 12.1 12.0 11.4 9.9 14.0 16.9 23.4 15.1 10.1 15.4 12.3 18.8 26.6 13.5 14.9 10.0 10.6 15.5 14.2 21.3 18.3 29.0 12.4 6.8 25.4 12.7 6.6 28.6 14.4 20.5 12.9 24.8 14.7 17.0 13.8 6.7 11.4 14.0 12.6 11.4 12.9 20.1 10.7 17.7 10.3 7.1 9.0 18.8 23.9 10.2 14.2 11.7 12.1 37.0 17.8 32.4 23.8 18.8 19.1 24.5 21.7 22.7 19.7 21.9 22.1 20.4 47.3 33.5 20.9 18.8 30.1 18.1 9.2 12.7 12.0 14.1 9.3 11.1 10.4 9.9 9.8 9.1 6.0 29.4 27.3 13.1 6.0 34.9 7.1 20.4 56.2 26.1 14.0 135.5 38.6 26.6 25.3 469.4 15.8 62.6 23.3 28.7 31.8 13.8 24.2 17.4 37.6 29.7 30.2 21.4 25.2 25.0 1260.7 20.4 23.9 13.5 47.7 27.2 28.4 29.0 71.9 24.4 60.6 112.4 12.9 10.5 91.2 49.8 9.5 47.9 33.7 27.6 26.7 WEE1 WEE1A ENSG00000166483 "WEE1 G2 checkpoint kinase" P30291 11 9573681-9593457 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" 4 "Basal glandular cells: 165.0;Suprabasal keratinocytes: 167.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004619, HPA068845" Approved Approved Nucleoli No No Nucleoli "CAB004619: AB_628447, HPA068845: AB_2686048" "unprognostic (6.04e-2)" "unprognostic (1.90e-3)" "unprognostic (1.09e-2)" "unprognostic (9.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-2)" "unprognostic (3.79e-3)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-2)" "unprognostic (3.21e-3)" "unprognostic (3.73e-1)" "prognostic unfavorable (5.19e-4)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (2.08e-1)" "unprognostic (3.80e-1)" 6.9 3.5 2.0 26.1 2.1 6.6 27.4 5.3 1.6 12.8 18.0 2.5 15.4 3.7 21.9 14.3 22.1 12.4 20.2 23.0 2.0 2.2 6.8 19.3 10.2 10.9 1.8 1.2 11.1 4.4 4.9 6.1 42.7 4.7 17.0 4.7 5.9 12.8 17.8 12.0 33.3 10.4 22.9 2.4 8.0 12.5 28.3 2.0 35.9 12.0 26.8 26.4 19.8 14.7 8.5 0.1 6.4 0.0 2.1 7.8 0.6 14.4 5.6 21.5 11.9 18.9 9.5 42.6 17.9 13.8 10.0 10.0 10.2 17.8 33.9 6.7 7.8 9.4 17.5 14.7 6.9 12.8 12.1 12.0 13.3 9.0 6.8 2.0 20.1 13.3 3.1 7.5 4.7 16.6 10.4 6.2 13.2 21.6 23.6 17.4 3.4 20.5 10.9 32.4 10.0 6.4 19.8 16.9 7.3 7.9 30.5 8.1 10.6 12.1 14.3 8.7 26.8 9.0 9.6 7.1 18.1 12.6 7.3 14.2 5.5 16.5 44.8 7.7 11.1 12.6 0.0 0.0 6.4 2.0 0.0 0.2 8.5 2.0 3.3 0.1 3.6 0.1 1.6 0.1 2.1 0.0 0.1 7.8 0.6 2.0 2.1 5.3 1.6 2.0 2.2 1.8 1.2 4.7 2.0 47.6 26.9 13.5 165.0 156.6 1.8 53.3 66.2 49.5 56.9 40.1 0.0 78.4 11.6 22.0 18.2 13.0 34.2 23.3 11.8 154.6 38.6 75.9 6.9 86.3 14.7 1.6 58.5 9.2 1.6 29.5 10.9 8.4 16.9 2.8 32.0 9.3 20.6 25.7 10.3 6.7 4.4 6.5 22.1 42.6 52.9 167.1 114.8 13.1 37.4 55.3 WEE2 FLJ16107 ENSG00000214102 "WEE1 homolog 2" P0C1S8 7 141708353-141731271 "Enzymes, Predicted intracellular proteins" Meiosis "Kinase, Transferase, Tyrosine-protein kinase" "Disease mutation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" 21 "Distal tubular cells: 1.7;Proximal tubular cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "CACO-2: 8.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA027418, HPA054280" Uncertain Enhanced Nucleoplasm,Cytosol NA NA Nucleoplasm Cytosol "HPA027418: AB_10603144, HPA054280: " "unprognostic (6.35e-2)" "unprognostic (1.47e-1)" "unprognostic (1.89e-1)" "unprognostic (3.18e-1)" "unprognostic (2.33e-1)" "unprognostic (4.00e-2)" "unprognostic (2.90e-1)" "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (3.02e-2)" "unprognostic (2.61e-1)" "unprognostic (1.76e-2)" "unprognostic (1.73e-1)" "unprognostic (3.25e-2)" "unprognostic (2.66e-1)" "unprognostic (6.07e-2)" "unprognostic (2.88e-3)" 0.6 0.1 0.5 0.3 1.0 0.0 0.4 0.8 0.6 0.6 0.1 0.0 0.7 0.0 1.3 0.7 1.6 1.3 0.5 0.6 1.3 0.1 0.3 1.6 0.6 1.2 1.1 0.0 1.0 0.0 0.3 0.0 0.9 0.0 0.7 2.8 0.4 0.0 0.8 0.4 0.8 1.3 2.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.2 0.4 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.4 0.1 0.1 0.0 0.3 1.0 0.3 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.3 0.5 1.6 1.2 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 0.2 0.1 1.7 1.1 0.5 0.0 0.4 0.7 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.4 0.6 0.0 0.1 0.1 0.6 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752593-911452 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein kinase inhibitor, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046541, HPA059157" Enhanced Supported Cytosol NA NA Cytosol "HPA046541: AB_2679690, HPA059157: AB_2683935" "unprognostic (1.40e-1)" "unprognostic (1.54e-2)" "unprognostic (4.82e-2)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (7.68e-2)" "unprognostic (1.05e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (4.38e-1)" "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" 30.0 12.4 49.3 19.1 47.5 28.9 45.4 22.5 36.7 21.2 12.6 42.6 10.6 8.5 15.9 19.4 45.5 16.9 16.5 38.5 53.7 36.4 45.6 18.0 33.0 34.3 62.3 27.1 18.5 11.3 29.1 12.7 20.3 41.4 17.1 14.3 12.0 15.4 20.3 43.4 31.3 10.3 22.3 82.8 16.9 15.7 23.8 38.8 23.9 16.7 17.4 24.5 18.9 26.5 3.7 2.6 10.9 7.1 2.1 5.2 1.9 14.1 26.8 35.4 3.3 25.6 24.6 13.5 14.1 17.0 15.3 14.3 15.0 16.1 20.0 5.0 30.2 18.6 10.7 23.9 16.3 21.6 34.5 14.3 44.5 35.6 13.0 18.8 24.0 19.4 19.0 24.8 25.3 45.4 17.0 20.7 18.8 20.3 48.2 23.1 13.0 43.2 4.0 28.9 12.0 6.4 20.6 39.3 5.3 22.0 30.6 10.3 12.1 32.9 21.4 9.5 49.5 23.5 24.7 22.8 19.0 22.0 26.6 20.7 7.4 12.2 30.2 18.1 12.7 15.4 0.9 2.7 2.6 3.8 4.0 5.2 3.0 4.3 3.6 2.6 3.7 2.3 4.1 10.9 2.1 7.1 1.7 4.9 1.9 49.3 47.5 22.5 36.7 53.7 36.4 62.3 27.1 41.4 38.8 95.3 107.5 34.5 38.1 100.2 81.8 197.8 58.6 61.6 53.4 85.5 141.4 27.8 72.9 26.9 18.6 99.1 21.1 210.2 21.1 25.9 54.1 46.4 50.8 62.5 49.6 79.4 56.4 45.4 101.9 17.5 57.2 66.8 35.4 48.7 24.6 57.2 32.3 29.8 52.3 16.5 92.4 12.9 41.9 139.7 38.1 118.8 23.8 69.2 21.9 46.1 WNK2 "KIAA1760, NY-CO-43, PRKWNK2, SDCCAG43" ENSG00000165238 "WNK lysine deficient protein kinase 2" Q9Y3S1 9 93184916-93320572 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.9;pancreas: 18.3;salivary gland: 19.5;skeletal muscle: 23.7" "Cell type enhanced" "Detected in many" 9 "Cone photoreceptor cells: 151.2;Rod photoreceptor cells: 101.2" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 5 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "Daudi: 11.5;Hep G2: 18.8;SCLC-21H: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015555, HPA016519, CAB017813" Enhanced Approved Cytosol NA NA Cytosol "CAB017813: , HPA015555: AB_2669218, HPA016519: AB_2669380" "unprognostic (5.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.79e-3)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (4.48e-3)" "unprognostic (6.51e-2)" "unprognostic (1.44e-1)" "unprognostic (4.38e-4)" "unprognostic (1.62e-1)" 0.0 0.7 3.9 0.9 3.8 0.0 1.2 9.5 7.2 0.7 7.5 7.4 1.3 1.5 2.1 6.6 0.1 21.9 4.0 4.2 0.0 0.0 0.0 0.0 2.6 0.0 18.3 0.8 7.5 0.9 4.9 4.8 19.5 5.5 23.7 3.0 6.2 1.6 1.1 0.5 3.0 1.5 0.0 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 0.3 0.0 4.4 4.0 2.9 8.2 0.0 0.0 5.6 0.0 0.0 0.0 0.0 1.6 0.1 11.5 1.5 0.0 0.8 0.2 6.5 0.0 0.0 0.0 7.5 0.0 3.5 18.8 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 7.3 0.0 0.0 6.0 0.1 0.1 7.3 4.4 0.2 0.0 0.0 9.3 0.0 0.7 23.9 9.4 1.5 6.5 0.6 0.8 0.8 1.3 0.1 0.0 3.1 0.1 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.1 1.1 57.3 56.7 30.6 5.3 9.1 0.0 151.2 11.9 0.0 11.7 0.9 0.5 34.4 0.0 8.0 5.6 1.1 12.9 0.0 0.0 2.9 1.6 31.2 0.6 1.0 1.9 0.9 0.0 1.7 1.0 57.9 60.6 3.3 42.1 5.6 0.7 101.2 12.9 4.4 0.4 6.6 4.8 13.0 0.0 51.8 6.4 WNK3 PRKWNK3 ENSG00000196632 "WNK lysine deficient protein kinase 3" Q9BYP7 X 54192823-54358642 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 31.6;testis: 26.7" "Cell type enhanced" "Detected in many" 15 "Cardiomyocytes: 178.0;Spermatogonia: 48.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "naive CD4 T-cell: 1.9" "Group enriched" "Detected in many" 10 "B-cells: 1.1;T-cells: 1.9" "Cell line enhanced" "Detected in some" "AF22: 5.9;AN3-CA: 4.5;HAP1: 6.8;NTERA-2: 11.9;SiHa: 5.8;SuSa: 5.3;U-2 OS: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077678 Approved Approved Vesicles NA NA Vesicles "HPA077678: AB_2686850" "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (2.44e-1)" "unprognostic (7.87e-5)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (1.85e-2)" "unprognostic (3.32e-2)" "unprognostic (3.38e-1)" "unprognostic (3.03e-2)" "unprognostic (5.78e-4)" "unprognostic (2.22e-1)" "unprognostic (2.64e-2)" "unprognostic (5.61e-2)" "unprognostic (9.99e-2)" "unprognostic (7.63e-2)" "unprognostic (8.74e-2)" 0.9 5.0 3.9 0.9 4.3 0.8 1.7 3.0 3.6 1.5 0.7 1.7 13.9 1.0 1.3 31.6 1.1 1.8 1.1 1.5 3.9 3.4 2.8 8.7 0.9 1.0 2.3 3.0 5.7 0.9 2.2 14.0 1.2 3.9 2.2 0.7 1.3 1.2 4.8 0.7 0.9 0.7 1.5 3.3 1.0 1.2 26.7 3.5 0.0 1.7 0.0 0.8 1.3 1.9 1.1 0.0 0.1 0.0 0.1 1.9 0.1 0.0 0.0 5.9 4.5 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 6.8 0.1 0.2 0.0 1.2 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.0 0.2 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 2.8 0.8 0.0 1.2 0.2 1.9 1.8 5.8 0.0 0.7 5.3 0.5 0.0 0.3 0.0 5.2 0.0 1.2 0.0 4.0 0.0 1.6 0.0 2.6 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 1.1 1.9 0.4 0.1 0.1 0.0 0.0 0.0 0.1 3.9 4.3 3.0 3.6 3.9 3.4 2.3 3.0 3.9 3.5 0.0 2.9 0.8 4.6 3.3 24.5 178.0 2.5 0.0 5.7 7.0 13.7 0.2 5.0 1.4 4.2 3.1 0.0 0.0 0.0 0.3 3.1 4.8 5.8 41.5 0.1 33.4 0.0 17.8 0.6 14.6 14.7 0.5 0.0 0.0 0.0 20.7 0.3 0.0 41.1 3.1 40.9 6.5 3.3 30.2 48.2 1.0 0.1 0.0 0.0 1.1 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780678-42796936 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease mutation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.1;ovary: 14.6" "Group enriched" "Detected in some" 7 "Distal tubular cells: 135.9;Mucus-secreting cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in single" "memory CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 19.9;K-562: 22.2;TIME: 21.4;WM-115: 14.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.1 0.0 0.8 5.8 0.2 0.0 2.6 0.6 0.3 0.7 12.9 0.4 0.4 2.1 0.2 2.8 8.7 0.5 1.0 0.2 2.6 0.0 28.1 0.2 0.4 0.1 0.1 0.3 14.6 1.0 0.0 2.4 0.0 1.7 11.1 11.7 12.2 1.4 1.2 0.0 0.5 3.3 0.4 0.8 0.1 2.6 0.4 0.2 0.0 0.0 0.2 2.0 0.3 0.4 0.4 0.0 0.0 0.3 0.0 1.0 0.0 1.2 0.6 0.2 0.0 0.2 0.1 2.9 7.4 2.9 2.8 0.9 0.4 0.5 0.2 4.4 19.9 0.7 0.0 0.1 0.2 4.8 0.4 1.0 0.0 0.0 2.9 4.7 0.0 0.4 2.5 0.4 4.0 1.2 1.4 0.2 0.2 22.2 0.7 0.0 0.6 0.0 0.5 0.2 1.2 5.1 0.3 0.7 0.0 0.0 0.3 0.0 0.1 0.0 0.1 1.0 2.7 1.4 1.6 21.4 0.2 1.9 0.2 0.1 3.6 3.1 0.7 0.0 1.2 14.5 0.0 0.3 0.0 0.0 0.0 0.7 0.4 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.3 2.6 0.0 0.1 0.3 1.7 0.2 0.0 1.1 0.0 0.1 0.0 0.2 0.7 2.5 5.3 1.2 7.0 0.0 0.0 135.9 0.0 0.0 0.0 1.1 0.0 0.2 0.1 0.0 6.5 4.6 0.0 0.0 0.0 12.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 39.6 0.0 0.1 2.9 0.4 0.5 0.3 0.0 0.3 0.7 0.8 0.4 0.0 0.0 13.3 0.1 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "basophil: 14.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 14.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA 4300000 "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 26.2 13.1 17.0 9.4 15.6 2.6 47.2 6.7 12.8 15.8 23.8 8.9 13.7 18.2 13.1 17.4 22.0 10.7 14.9 17.9 14.8 12.4 22.6 43.2 23.6 13.7 15.8 6.6 13.2 21.4 16.7 10.7 31.3 16.8 12.2 17.3 6.5 23.7 21.0 10.6 12.3 24.8 18.8 16.8 34.5 15.5 13.6 12.0 8.1 16.8 15.6 7.1 21.9 17.5 0.1 0.1 14.7 0.0 1.0 2.5 0.6 14.4 7.2 22.8 17.8 13.7 17.0 26.8 9.6 19.7 11.4 15.7 17.1 10.7 0.0 10.3 16.3 14.6 8.5 21.3 17.1 22.4 0.0 7.2 4.3 7.1 11.9 11.1 3.3 7.7 13.0 18.4 17.2 19.2 14.2 38.4 2.4 18.7 6.4 16.2 9.9 2.0 4.3 14.4 8.8 9.2 2.5 17.9 1.2 16.6 17.2 4.6 5.4 19.9 15.1 12.6 15.7 10.4 6.9 33.0 28.1 31.2 21.2 25.9 5.6 2.7 0.8 10.6 4.7 16.6 14.7 0.0 0.9 2.5 0.0 1.6 0.1 0.5 1.4 0.0 0.0 1.2 1.9 0.0 1.0 0.0 0.1 0.1 0.6 17.0 15.6 6.7 12.8 14.8 12.4 15.8 6.6 16.8 12.0 23.8 30.8 1.5 33.5 53.3 6.2 16.5 20.4 26.8 34.2 27.9 5.9 28.2 3.3 25.6 20.2 77.6 27.4 0.0 34.0 20.3 31.2 52.1 12.8 33.4 4.3 3.2 21.9 41.1 5.6 7.9 17.0 5.3 23.6 1.0 35.7 16.3 40.3 21.0 12.0 38.5 8.0 19.4 20.6 12.8 11.7 43.4 38.1 15.2 31.0 58.7 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713560-97739862 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease mutation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "blood: 37.4;lymphoid tissue: 107.1" "Cell type enriched" "Detected in many" 4 "T-cells: 96.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 41 "gdT-cell: 37.4;MAIT T-cell: 25.4;memory CD4 T-cell: 19.6;memory CD8 T-cell: 29.2;naive CD4 T-cell: 14.3;naive CD8 T-cell: 21.9;NK-cell: 26.4;T-reg: 19.9" "Group enriched" "Detected in many" 53 "NK-cells: 26.4;T-cells: 37.4" "Group enriched" "Detected in some" 11 "JURKAT: 39.8;MOLT-4: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB002625, HPA003134" Enhanced NA NA "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favorable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favorable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favorable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 2.2 0.5 0.3 18.1 0.6 11.2 1.5 0.7 0.6 1.2 3.7 0.7 0.3 2.9 1.2 1.1 1.7 1.5 2.8 0.9 0.4 0.8 2.2 2.3 5.8 28.1 0.8 0.6 0.9 1.3 0.0 0.7 0.9 0.6 2.1 0.6 1.0 5.5 1.0 0.7 1.0 12.3 0.7 0.7 24.8 3.2 1.4 0.6 107.1 2.5 1.1 20.8 3.0 1.7 0.4 0.2 0.5 0.2 26.4 37.4 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.8 0.0 0.2 0.0 0.0 57.4 0.1 0.0 0.0 0.0 2.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.1 37.4 0.1 25.4 0.0 19.6 29.2 0.0 0.4 14.3 21.9 0.5 26.4 0.2 0.2 19.9 14.3 0.3 0.6 0.7 0.6 0.4 0.8 0.8 0.6 0.6 0.6 8.9 22.3 1.4 0.0 1.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.4 0.1 2.3 0.6 1.7 0.0 0.0 3.1 0.8 0.7 0.0 1.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.4 1.7 1.3 0.0 96.4 0.0 0.1